anti-diabetic phytodrugs

Presented by Dr. Sudhakar KokateDirector PPRC, India

Emerging trends

in

Phyto-drugs

for

Diabetes control

PPRC/INDIA 01

PPRC/INDIA 02

Diabetes

Most common endocrine disorder

Multi-factorial disease

Affects health-care systems

Also affects the quality of life and life

expectancyPPRC/INDIA 03

Estimation to affect > 221 million by the year

2010

About 300 million by 2014

Diabetic patients increasing globally with the

advance in time

Diabetes

PPRC/INDIA 04

Characteristics

Disorder of the carbohydrate, fat and protein

metabolism

Hyperglycaemia

Abnormalities in lipid metabolism

Oxidative stressPPRC/INDIA 05

Diab

etes

is ca

used

by

PPRC/INDIA 06

Effects of Diabetes

The chronic hyperglycaemia leads to severe complications that affect:

–Eyes

–Kidney

–Nerves

–ArteriesPPRC/INDIA 07

If not controlled

Develop micro & macro vascular complications :

Cardio-vascular diseases

Blindness

Renal failure

Limb amputation

Poor wound healingPPRC/INDIA 08

PPRC/INDIA 09

Types of diabetes

Insulin – dependant: IDDM

Non – insulin dependant: NIDDM

PPRC/INDIA 10

Drugs for diabetes control

Acarbose Oral

Amaryl Oral

Byetta SubQ

Chlorpropamide Oral

DDAVP Oral

Desmopressin Oral

Exenatide SubQ

Fortamet Oral

Fortamet Oral

Glipizide Oral

GlucaGen Inj

Glucotrol Oral

Glimepiride Oral

Humulin R Inj

PPRC/INDIA 11

Drugs for diabetes control

Onglyza Oral

Prandimate Oral

RIOMET Oral

Sitagliptin Oral

Tradjenta Oral

Vitcoza SubQ

& many more…………..

Humalog SubQ

Insulin Lispro SubQ

Janumet Oral

Januvia Oral

Lantus SubQ

Miglitol Oral

Novolin R In

PPRC/INDIA 12

PPRC/INDIA 13

The exploitation of plants

has received more prominence

worldwide

WHY?????

PPRC/INDIA 14

Reasons

Health benefits

Easy availability

Curing varied diseases

Economical

Effective

No side effects

PPRC/INDIA 15

Diab

etes

cont

rol

PPRC/INDIA 16

PPRC/INDIA 17

PPRC/INDIA 18

PPRC/INDIA 19

Herbs / Medicinal plants

used in

Diabetes Control

PPRC/INDIA 20

Acacia nilotica

PPRC/INDIA 21

PPRC/INDIA 22

Acalypha ciliata

PPRC/INDIA 23

PPRC/INDIA 24

Adiantum capillus veneris

PPRC/INDIA 25

PPRC/INDIA 26

Aegle marmelos

PPRC/INDIA 27

PPRC/INDIA 28

Aesculus hippocastanum

PPRC/INDIA 29

PPRC/INDIA 30

Allium species

PPRC/INDIA 31

PPRC/INDIA 32

Aloe vera

PPRC/INDIA 33

PPRC/INDIA 34

Andrographis paniculata

PPRC/INDIA 35

PPRC/INDIA 36

Anemarrhena asphodeloides

PPRC/INDIA 37

PPRC/INDIA 38

Angelica archangelica

PPRC/INDIA 39

PPRC/INDIA 40

Aralia elata

PPRC/INDIA 41

PPRC/INDIA 42

Asteracantha longifolia

PPRC/INDIA 43

PPRC/INDIA 44

Azadirachta indica

PPRC/INDIA 45

PPRC/INDIA 46

Bixa orellana

PPRC/INDIA 47

PPRC/INDIA 48

Borassus flabellifer

PPRC/INDIA 49

PPRC/INDIA 50

Bougainvillea spectabilis

PPRC/INDIA 51

PPRC/INDIA 52

Boussingaultia baselloides

PPRC/INDIA 53

PPRC/INDIA 54

Brassica species

PPRC/INDIA 55

PPRC/INDIA 56

Bridelia ferruginea

PPRC/INDIA 57

PPRC/INDIA 58

Calligonum comosum

PPRC/INDIA 59

PPRC/INDIA 60

Camellia sinensis

PPRC/INDIA 61

PPRC/INDIA 62

Caralluma tuberculata

PPRC/INDIA 63

PPRC/INDIA 64

Cassia fistula

PPRC/INDIA 65

PPRC/INDIA 66

Chrysanthemum morifolium

PPRC/INDIA 67

PPRC/INDIA 68

Cinnamomum tamala

PPRC/INDIA 69

PPRC/INDIA 70

Coccinia indica

PPRC/INDIA 71

PPRC/INDIA 72

Colchicum luteum

PPRC/INDIA 73

PPRC/INDIA 74

Commelina communis

PPRC/INDIA 75

PPRC/INDIA 76

Cuminum cyminum

PPRC/INDIA 77

PPRC/INDIA 78

Curcuma longa

PPRC/INDIA 79

PPRC/INDIA 80

Cyamopsis tetragonoloba

PPRC/INDIA 81

PPRC/INDIA 82

Daucus carota

PPRC/INDIA 83

PPRC/INDIA 84

Dioscorea dumetorum

PPRC/INDIA 85

PPRC/INDIA 86

Eriobotrya japonica

PPRC/INDIA 87

PPRC/INDIA 88

Eugenia jambolana /

Syzygium cumini

PPRC/INDIA 89

PPRC/INDIA 90

Ficus benghalensis

PPRC/INDIA 91

PPRC/INDIA 92

Galega officinalis

PPRC/INDIA 93

PPRC/INDIA 94

Geranium core-core

PPRC/INDIA 95

PPRC/INDIA 96

Gymnema sylvestre

PPRC/INDIA 97

PPRC/INDIA 98

Hexachlamys edulis

PPRC/INDIA 99

PPRC/INDIA 100

Hibiscus vitifolius

PPRC/INDIA 101

PPRC/INDIA 102

Holarrhena antidysenterica

PPRC/INDIA 103

PPRC/INDIA 104

Inula racemosa

PPRC/INDIA 105

PPRC/INDIA 106

Ipomoea batatas

PPRC/INDIA 107

PPRC/INDIA 108

Juglans regia

PPRC/INDIA 109

PPRC/INDIA 110

Juniperus communis

PPRC/INDIA 111

PPRC/INDIA 112

Lagerstroemia speciosa

PPRC/INDIA 113

PPRC/INDIA 114

Laurus nobilis

PPRC/INDIA 115

PPRC/INDIA 116

Lycii cortex&

Lycii folium

PPRC/INDIA 117

PPRC/INDIA 118

Lupinus termis

PPRC/INDIA 119

PPRC/INDIA 120

Malva verticillata

PPRC/INDIA 121

PPRC/INDIA 122

Moringa oleifera

PPRC/INDIA 123

PPRC/INDIA 124

Mimosa pudica

PPRC/INDIA 125

PPRC/INDIA 126

Momordica charantia

PPRC/INDIA 127

PPRC/INDIA 128

Mori folium

PPRC/INDIA 129

PPRC/INDIA 130

Morinda lucida

PPRC/INDIA 131

PPRC/INDIA 132

Morus alba

PPRC/INDIA 133

PPRC/INDIA 134

Murraya koenigii

PPRC/INDIA 135

PPRC/INDIA 136

Musa sapientum

PPRC/INDIA 137

PPRC/INDIA 138

Nelumbo nucifera

PPRC/INDIA 139

PPRC/INDIA 140

Nicotiana glutinosa

PPRC/INDIA 141

PPRC/INDIA 142

Ocimum sanctum

PPRC/INDIA 143

PPRC/INDIA 144

Olea europaea

PPRC/INDIA 145

PPRC/INDIA 146

Opuntia ficus indica

PPRC/INDIA 147

PPRC/INDIA 148

Papaver somniferum

PPRC/INDIA 149

PPRC/INDIA 150

Parkia speciosa

PPRC/INDIA 151

PPRC/INDIA 152

Panax notoginseng

PPRC/INDIA 153

PPRC/INDIA 154

Peganum harmala

PPRC/INDIA 155

PPRC/INDIA 156

“BE WITH US”

Thank You!!