an efficient synthesis of aryl α-keto esters

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2005

Oxocarboxylic acids and estersQ 0460 An Efficient Synthesis of Aryl α-Keto Esters. — A new access to synthetically

important α-keto esters is based on the diazo transfer oxidation of esters such as (I), (III) and (VI) and subsequent oxidation of the resulting diazo group. The process can be conducted in one pot or with isolation of the intermediate α-diazo ester. — (MA, M.; LI, C.; PENG, L.; XIE, F.; ZHANG, X.; WANG*, J.; Tetrahedron Lett. 46 (2005) 22, 3927-3929; Key Lab. Bioorg. Chem. Mol. Eng., Minist. Educ., Coll. Chem., Peking Univ., Beijing 100871, Peop. Rep. China; Eng.) — Mais

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