2016 0302嶋根先生報告書2 - ncnp...61.5%>&2013 º>' ? }85.8%>&2015...

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1995 11 5,000

3502015 9 10

3085 61.7% 3076 52.3% 43.3

3. 61.5% 2013 85.8% 201556.9%

4. 1.5% 1.0% 0.5% MDMA0.1%0.1% 0.3% 2.4%

5. 47.9 41.3 44.1 MDMA40.0

45.4 45.7 40.8 45.56. 138 95 50

12 MDMA 12 312013

7. 9394 MDMA 42 58

8. 1 34.3% 1995 62.9% 2015

- 7 -

3 1.6% 1999 2.5% 2015 9. 1 1995 4.0% 2007 7.7

2015 6.1% 2007 2.7%2011 1.9% 2015 2.9%

1

20%

MDMA2013

MDMA

258

160%

26 7

1990 19921,100 1993

3,000 19943,300

1-3 1995

114-13

2014 9 10 1

14)

- 8 -

2,297 20155

2014 12

2015

5,000 ( 350) 2

2015 9 10 10 4

15 645000

1) 11

2) 65 A

23

21 20 11 10 11 10 11

11 27 4

126 1

1

15 6480,038,406

3) 5,000 65

10 16

4) 122

11

2

1 = 15

64

5) 22

- 9 -

6)

2

15 64

A2014-149

41)

2) 1 30

3) 1 30

4)

4

121) Prevalence

prevalence

prevalence1~6

2) 7 133) 14 204)

21 275) 28346) 35 417) 42488)

49 559) 56

6210)

63 6911)

70 7612)

77 8313) 2~33 84 91

- 10 -

30

(1) NSAIDs(2)

/(3)

®

2) 1211 10 60

7 7/

/

2 t 3ANOVA

15

5,000 3,08561.7% 1915

45.8%31.3% 10.9%

B42.9%

49.1% 8.2%13.2% C

60 63.2% 20 31.5%

2038.7% 60 18.9%

2018.1% 60 5.7%

D

61.2% 58.7%35.0% 35.7%

37.2%35.7% 35.6%

14.6% 17.2%

1 1995 20151995 78.9%

2003 70%2005 60%

2007 2013 50%60%

76 403076

5247

5076

7 1347

30.8%52.3% 47.7%

43.3 4024.4% 50 22.6% 30

18.0% 45.7%14.2% 12.8%

38.6%30.2%

13.2%6.9%

68.1%2.7%

1

- 11 -

25.6%5 13.8%

6 1420 93.8%

1 80.2% 30 67.0%30

70.9%61.3% 75.0%

59.7%20 76.7% 10 14.9%

3079.4%

81.8%1 2

72.0%59.8% 1

26.2% 30 23.2%30

33.6%21.3%

37.9% 11.8%30 29.1%

10 2.7% 30

36.3%51.5%

45.0% 22.8%

31.2%

21 2771.3% 55.6%

55.3% 164.7%

63.0% 37.1%

5, 28 341 62.9%

30 26.9%3 2.3%

4.5%1.5%

1.5% 3.0%2.0% 60 3.6%

5.1%3.4%6.2%

4.7% 2.3%

3.3%

39.3%25.7%

12.9%0.9% 0.1%

39.5% 10.9%

39.8%30

97.9%0.6%

5, 35 411

5.6% 30 4.2%3 3.0%

5.7% 1.3%1.3% 3.4%

2.8% 604.0%

12.3%6.2%

5.7% 2.9%

- 12 -

5.1%

4.4% 0.1%

3.2%2.2% 1.5%

0.03%

82.3%6.5%

5, 42 481 6.1%

30 4.3% 32.8%

3.8%0.6%

3.4% 2.4%60 5.1%

11.2%5.7%

7.1%2.6%

5.1%

4.5%0.1%

5.1%0.03%

80.9%

6.7%30

3.9%

495596.1% 93.2%90.5% 88.0% 87.4%

4.4% 5.3%

97.9% 96.0%92.3% 78.5%

78.0%60.8%

89.9%

82.7%

1.2%

89.9%

0.7%

1, 56 620.4%

0.3% 1

0.3%0.2% 0.1%

1.5%

0.5%0.2% 30 0.7%

0.5%3.1%

0.9%

- 13 -

0.3%5

0.9%85.8%

56.9%

76.5%77.8%

52.3%61.9% 10

49.1% 60 62.6%

60.7%50.0%

66.5%46.9%

65.2%46.9%

57.2%35.5% 5.8%

1.1%

2,4, 63 69

2.4%2.0% 1.0% MDMA 0.6%

0.2% 0.2%0.6% 4.1%

3.1% 0.5%0.7% 30 1.4%1.0%1.5%

1.9%2 3 1.1%

4.5% 2.7% 2.5%MDMA 1.4% 1.3%

1.2% 1.6%5.9%

3.1% 1.0%2.1% 20 30

2.4% 2.4%3.1%

1.9%3 5

2.5%

3, 70 76

52.4% 14.6%13.1% MDMA 13.0%

11.5% 11.1%21.8% 53.5%

25.0% 18.2%22.2% 60 11.2% 3024.1% 13.4%23.2% 18.0%

33.3%5 25.3%

1, 77 83 E1

1.5%1.0% 0.5% MDMA 0.1%

0.1% 0.3%2.4%

- 14 -

47.941.3 44.1 MDMA40.0

45.4 45.740.8 45.5

1 0.1%0.1% 0.0% MDMA 0.0%

0.0% 0.0%0.0% 0.1%

2,3, 84 11 2011 85.0%

2013 81.9% 2015 79.8%10 1

10 1 200750.6%

2015 25.2%4,5

2009 66.4%65.0% 2011 64.0%

2013 59.8% 201520

20 200171.2% 42.9%

20156,7 84 1

1 2001 36.0%2015 26.9%

10 2013 2.6%2015 4.5%

8,9, 851

34.3% 199562.9% 2015

31.6% 1999

2.5% 201510,11, 85

1 2007

2.6%1999 2.9% 2013 3.1% 2015

12,13, 851 1995 4.0%

2007 7.72011 5.6% 2015 6.1%

2007 2.7%2011 1.9% 2015 2.9%

14,15

2.9% 2009 2.8% 20112.4% 2013 1.5% 2015

20132015

16,17

1.7% 2009 1.4% 20110.9% 2013 0.8% 2015

2013 201520 50 60 10

3018

1

2013 2015

19

- 15 -

20.1%51.5% 2 2031

32, 86,87

2013 20150.9% 1.0% MDMA 0.4% 0.6%

33, 89,900.4% 2013

0.3% 20151.9% 1.5% 1.1% 1.0%

MDMA 0.3% 0.1%

87

229191 94

16 20MDMA 58 52

201393 94 MDMA

42 58

90

138 9550

12 MDMA 1231

2013

2013 50%61.7%

47 3085

1995

0.4% 20130.3% 2015 1

0.1% 2013 0% 2015

31 201340

- 16 -

2,297 2015 5

61.5% 2013 85.8% 2015

56.9%

20%

5

MDMA 2013

MDMA

90

20132015 10 30

MDMA

1 62.9%1 2007

BZBZ

etizolam flunitrazepamtriazolam

14) 3

30

0.6% BZ 3.9%

- 17 -

12,297 2015 5

20%

1) 4

4pp.9-23, 1993.

2) 5

5pp.5-26, 1994.

3)6

6pp.5-34, 1995.

4)

7

7 1 pp.5- 35, 1996.

5)

9

9 1 pp.7- 48, 1998.

6)11

pp.17-70, 2000.3. 7)

13

pp.15-77, 2002.3. 8)

15

pp.17-87, 2004.3.

9)17

pp.17-105, 2006.

- 18 -

10)19

pp.15-95, 2008. 11)

(2009 ) 21

pp.15-95, 2010.

12)(2011

23

pp.15-95, 2012. 13)

2013 25

17-94,2014. 14)

26

95-128,2015.

1)

YAKUGAKUZASSHI 136(1) 79-872016.

2)37 6 4

8 2015. 3)

. Be! 120 , , ,

p42-47, 2015. 4)

26 1 44-49 2015.

1)

S52

1352015.3.25-28.

H.

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A

1 1995-2015

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B

C

D

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2 1 2005-2015

3 1 2005-2015

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4 1999-2015

5 1999-2015

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6 1 2001-2015

7 1 2001-2015

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8 1 1995-2015

9 1999-2015 3

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10 1 1995-2015

11 1999-2015 3

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12 1 1995-2015

13 1999-2015 3

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14 2009-2015

15 1999-2015

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16 2009-2015

17 1999-2015

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18 1 1995-2015

19 1999-2015

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20 1999-2015

21 1999-2015

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22 1999-2015

23 1999-2015

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24 1999-2015

25 1999-2015

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26 1999-2015

27 1999-2015

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28 1999-2015

29 1999-2015

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30 MDMA 1999-2015

31 MDMA 1999-2015

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32 1995-2015

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33 1995-2015

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