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Vendredi 8 mars 2019
12h-13h30
Hôpital du Saint-Sacrement, salle L0-19 sanofi-aven tis
« Genome wide meta-analysis of parent-of-origin effects of asthma, atopy and airway
hyperresponsiveness in four cohorts »
Aida Eslami, Ph.D. Postdoctoral Research Fellow Dr. Denise Daley's research group Centre for Heart and Lung innovation Providence Heart + Lung Institute St. Paul's Hospital, Burrard Building Vancouver, BC
Invitée par le comité de recrutement de l’axe Santé des populations et pratiques optimales en santé
IRIS 1645359
Objectifs d'apprentissage :
- Genomic imprinting (parent-of-origin effects)
Résumé de la conférence :
Asthma is a complex disease caused by a combination of genetic and environmental factors. The main genetic effects of the common Single Nucleotide Polymorphisms (SNPs) identified by Genome-Wide Association Studies (GWAS) do not fully explain the heritability of asthma. Genomic imprinting (parent-of-origin effects) is a potential mechanism which may explain this missing heritability. We aimed to identify candidate genomic regions for imprinting in asthma, atopy and airway hyperresponsiveness.
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