alopecia and hair restoration

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    Copyrighted by dr. Mohamed El Rouby

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    Management of Alopecia

    An Overview:

    Anatomy and Physiology

    Androgenetic Alopecia

    Classification Systems

    Medical Therapy

    Surgical Therapy

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    Hair

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    Scalp Layers

    S:skin

    C: subcutaneoustissues, connectivetissue,

    A: aponeurosis,

    L: loose areolar

    tissue,

    P: periosteum.

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    Blood and Nervous Supply

    Frontal

    Supratrochlear

    Supraorbital

    Temporal

    Superficial temporal Zygomaticotemporal

    Parietal

    Retroauricular

    Auriculotemporal/Great

    Auricular/LesserOccipital

    Occipital

    Occipital

    Greater occipital

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    Hair Follicles

    Embryonic development

    at 9-12 weeks

    Ectoderm

    Hair matrix cells Melanocytes

    Mesoderm

    Erector pili

    Dermal papilla

    Follicular Sheath

    Blood Vessels

    C i h d b d M h d El R b

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    Hair Shaft

    Cuticle

    Medulla

    Cortex

    Sheath

    C i ht d b d M h d El R b

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    Hair Density

    5 million follicles

    100,000-150,000 on thescalp

    Birth: 1135/cm2

    1 year: 795/cm2

    20-30: 615/cm2

    30-50: 485/cm2

    80-90: 435/cm2

    C i ht d b d M h d El R b

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    Follicular Units

    1-4 terminal hairs

    1-2 vellus hairs

    Sebaceous glands

    Erector pili muscles

    Blood vessels

    Nerves

    Connective tissue

    C i ht d b d M h d El R b

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    Hair Growth Cycle

    C ight d b d M h m d El R b

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    Types of Alopecia

    Androgenetic Alopecia

    Alopecia Areata

    Cicatricial Alopecia

    Traumatic Alopecia

    Diffuse Alopecia

    Copyrighted by dr Mohamed El Rouby

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    Androgenetic Alopecia

    Male Pattern Balding

    Female Pattern Balding

    PathophysiologyMiniaturization of

    follicles

    Decreased anagen/

    increased telogen

    Increased latency

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    Androgenetic Alopecia

    Autosomal dominantvariable penetrance

    30% of white men by

    age 3050% of white men by

    age 50

    Copyrighted by dr Mohamed El Rouby

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    Androgenetic Alopecia

    Site-specific action of androgensPubic/axillary/chest/beard:

    vellus terminal

    Scalp: terminal vellus

    Mentestosterone

    Womenadrenal androgens

    5-alpha reductase

    Testosterone dihydrotestosteroneWhy the pattern of hair loss?

    Increased follicle susceptibility

    Copyrighted by dr Mohamed El Rouby

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    Norwood Classification (men)

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    Ludwig Classification (Women)

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    Medical Therapy

    MinoxidilAntihypertensive

    Side effect: hyper-

    trichosis

    Topical 2%, 5%

    Stop progressionand reverse

    changesDelayed onset

    Prolonged use

    FinasterideSpecifically inhibits

    5-alpha reductase,type 2

    Lowers dihydro-testosterone levels

    1mg/day

    Side effect:

    decreased libidoNot used in women

    Copyrighted by dr. Mohamed El Rouby

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    Why treat?

    Lower self-esteem

    Mental distress

    Stereotypes

    Older

    Weaker

    Less productive

    Less attractive

    Less virile

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    Patient evaluation for surgery

    Expectations?

    Motivations?

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    Patient evaluation for surgery

    Donor Hair

    Type I

    Type II

    Type III

    Type IV

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    Patient evaluation for surgery

    Age

    Is NOT a contra-

    indication forsurgery

    Established pattern

    Hair color

    Co-existing medicalconditions

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    C py g by a by

    Surgical Therapy

    Scalp reduction

    Scalp flaps

    Hair grafting

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    py g y y

    Scalp Reduction

    Unger and Unger, 1978

    Many patterns

    Sagittal midline ellipse

    Y Lateral pattern

    Transverse ellipse

    Crescent ellipse

    S, J, C, U, T,I

    Easy to perform

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    py g y y

    Scalp Reduction--Pitfalls

    TensionExcessive reduction

    Tissue necrosis,widened scar

    Raposio &Nordstrom

    500-1,500 gr

    Galeotomies

    40% reduction intension

    Stretch-back Tendency for the

    remaining baldscalp to expand

    after a reduction 10-50% of the

    reduction

    2 months

    Copyrighted by dr. Mohamed El Rouby

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    py g y y

    Scalp extenders

    Frechet, 1993

    1mm thick silastic,

    two rows titaniumhooks

    200% stretch

    Memory

    Effect: negativestretch-back

    Copyrighted by dr. Mohamed El Rouby

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    py g y y

    Anchoring Galeal Flaps

    Raposio, et al., 1998

    Leave galea attachedto one scalp flap

    Create 3 2x3cmgaleal flaps

    Suture flaps toundersurface of

    opposite galea80-88% reduction instretch-back

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    py g y y

    Nordstrom Suture

    Nordstrom et al., 2001

    Silicone polymersuture, 2mm

    diameter, cuttingneedle

    Running, buried,mattress suture

    Negative stretch-back3x greater than withextenders

    Copyrighted by dr. Mohamed El Rouby

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    Tissue Expanders

    Increases total hair-bearing surface area

    Placement/Incisions

    Filling

    Useful in conjunction

    with scalp reductionsor scalp flaps

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    Scalp Flaps

    Lateral

    Temporoparietal

    Occipital (TPO),AKA Juri

    Preauricular

    Free flap

    Copyrighted by dr. Mohamed El Rouby

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    Juri Flap

    Uses: recreatefrontal hairline

    Parietal branch of

    superficialtemporal artery

    Flap

    Pedicle: 2-2.5cm

    Width: 4-6cmLength: 23-25cm

    Delay

    Copyrighted by dr. Mohamed El Rouby

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    Juri Flap

    Design hairline

    Elevate flap

    Close donor site

    Inset flap

    Resect bald scalp

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    Free Juri Flap

    Advantages

    1. Avoid delay

    2. Avoid revision

    around pedicle

    3. More naturalpattern of frontal hair

    growth

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    Hair grafting

    Okura, 1939

    Orentreich, 1959

    Punch graft

    Strip graft

    Follicular-unit graft

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    Punch grafting

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    Punch grafting

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    Strip Grafting

    Vallis, 1964

    Free composite graft

    Reconstruct frontal

    hairlineDimensions

    Length

    WidthUn-operated

    Previousoperation

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    Strip Grafting

    Vallis, 1964

    Free composite graft

    Reconstruct frontal

    hairlineDimensions

    Length

    WidthUn-operated

    Previousoperation

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    Follicular-unit Grafting

    Minigrafts

    3-4 hairs/graft

    Micrografts

    1-2 hairs/graft

    Barreras technique

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    Follicular-unit Grafting

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    Follicular-unit Grafting

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    Follicular-unit Grafting

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    Follicular-unit Grafting

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    Follicular-unit Grafting

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    Follicular-unit Grafting

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    Follicular-unit Grafting

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    Follicular-unit Grafting

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    Follicular-unit Grafting

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    Revision Surgery

    Removal

    Repositioning

    Reduction

    Addition

    Scar revision

    Copyrighted by dr. Mohamed El Rouby

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    Conclusion

    Wide variety of methods for the correctionof alopecia

    Dont forget medical management

    Individualize treatment plans

    Counseling, Counseling, Counseling

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