all-cause and cause-specific mortality in people using ... · violence 10 x . excess mortality...
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All-cause and cause-specific mortality in people using
extra-medical opioidsSarah Larney, Lucy Thi Tran, Janni Leung, Thomas Santo Jr., Damian Santomauro, Matt Hickman, Amy Peacock, Emily
Stockings, Louisa Degenhardt
@SarahLarney
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2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016
Deat
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00,0
00Opioid overdose deaths per 100,000,
Australia
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Aim: estimate all-cause and cause-specific mortality rates and excess mortality
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97 cohorts – 117 publications28 countries (5 LMIC)N 35 – 306,786person-years 29 - 687,673
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All-cause crude mortality rate:1.7 per 100 py
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All-cause deathsoccur at 10 xexpected rate
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Drug-related deaths: highest cause-specific mortality 0.5 per 100 py
40-60 x expected rate
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Excess mortality across causes:
AIDS-related 19 x
Liver-related 9 x
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Excess mortality across causes:
Suicide 8 x
Unintentional injuries 7 x
Violence 10 x
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Excess mortality across causes:
Respiratory 11 x
Cardiovascular 5 x
Cancer 3 x
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Poisoning 32% NCD 24%Infectious diseases 20%
Trauma 18%
Unknown 7%
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Poisoning 32%
Other NCD 13%
Cancer 7%Liver 5%
HIV 15%
Other trauma 10%
Unknown 7%
Suicide 8%Other ID 4%
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Multiple strategies to address multiple
exposures
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