alkyl halides - faculty.kfupm.edu.sa · only alkyl halides with sp3 hybridized head carbons undergo...
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![Page 1: Alkyl Halides - faculty.kfupm.edu.sa · Only alkyl halides with sp3 hybridized head carbons undergo nucleophilic subsitiution reactions Title: Mar 28 10:49 AM (14 of 36)](https://reader030.vdocuments.us/reader030/viewer/2022011813/5e432bacc8909b705724d3a1/html5/thumbnails/1.jpg)
Ch 5 Alkyl Halides;
Substitution and Elimination reactions
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Is Organic Chemistry onlybased upon Memorization?
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No, Organic Chemistryis based upon Understanding!
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The Relationship between STRUCTURE and REACTIVITY
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The Relationship between STRUCTURE and REACTIVITY
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ALKYL HALIDES
SUBSTITUTION ELIMINATION
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Leaving group
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Title: Mar 28 10:49 AM (8 of 36)
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Title: Mar 28 10:49 AM (9 of 36)
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General Case
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reaction of a nucleophile and an alkyl halide
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reaction of a nucleophile and an alkyl halide
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Title: Mar 28 10:49 AM (13 of 36)
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Only alkyl halides with sp3 hybridized head carbons undergo nucleophilic subsitiution reactions
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Title: Mar 28 10:49 AM (15 of 36)
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Title: Mar 28 10:49 AM (16 of 36)
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What is(are) the major product(s) of the following reaction?
(A) (B)
(A) & (B)
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INVERSIONof stereochemistry
Stereochemistry of the reaction
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Title: Mar 28 10:49 AM (19 of 36)
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Title: Mar 28 10:49 AM (20 of 36)
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Rate of Reaction =
reactions have 2nd order Kinetics
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Title: Mar 28 10:49 AM (22 of 36)
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Title: Mar 28 10:49 AM (23 of 36)
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Title: Mar 28 10:49 AM (24 of 36)
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Title: Mar 28 10:49 AM (25 of 36)
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Title: Mar 28 10:49 AM (26 of 36)
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Tertiary alkyl halides DO NOT undergo reactions
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Title: Mar 28 10:49 AM (28 of 36)
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Title: Mar 28 10:49 AM (29 of 36)
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Title: Mar 28 10:49 AM (30 of 36)
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Rate of Reaction =
reactions have 1st order Kinetics
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What is(are) the major product(s) of the following reaction?
(A) & (B)
(A) (B)
ol ol
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Title: Mar 28 10:49 AM (33 of 36)
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Title: Mar 28 10:49 AM (34 of 36)
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Title: Mar 28 10:49 AM (35 of 36)
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Title: Mar 28 10:49 AM (36 of 36)