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    Anesthesia for Spine

    Surgery

    Irene P. Osborn, M.D.

    Mount Sinai Medical Center

    New York, NY

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    Lecture Goals

    Overview of modern concepts in

    understanding of the spinal cord disease

    Review controversies in anesthesia for spine

    surgery

    Provide strategies for improving patient care

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    Why spine? 29.9 million people reported

    musculoskeletal impairments.

    Back/spine was most frequent,

    representing 51.7%. Impairment is

    most prevalent in 45-64 year old group.

    AAOS, Musculoskeletal

    Conditions in the U.S., Feb1992

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    Changing times

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    General Indications for Spine

    Surgery Neurologic dysfunction (compression)

    Structural instability

    Pathologic lesions

    Deformity

    Pain

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    Spinal Cord Anatomy Structure

    Blood supply

    Autoregulation?

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    Normal C-Spine Films

    Lateral view

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    Typical Pathologies

    Disc lesions

    Spinal canal

    stenosis

    Tumors

    Trauma

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    Spinal Cord Injury: Incidence/

    Etiology

    10, 000 new

    cases/year in US

    Males> females

    Causes:

    MVA- 40-50%Falls- 20%

    Recreational activities-

    7-15%

    violence

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    Cervical Spine Injury Occurs in 10% of head-injured patients

    Suspect when patient is flaccid, has

    diaphragmatic breathing, hypotension,bradycardia

    Minimize head movement during airway

    management In-line stabilization, rather than in-line

    traction, during laryngoscopy

    Criswell JC, et al: Anaesthesia 1994; 49:900-903

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    Suspected Cervical Spine Injury

    Neck pain

    Neurologic symptoms, signs

    Unconscious

    Mechanism of injury

    Intoxication Spondylosis, rhumatoid arthritis

    Significant head injury, facial fractures

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    Secondary Injury Activation of

    biochemical,

    enzymatic andmicrovascular

    Hemorrhagic necrosis,

    edema, inflammation

    Vascular stasis,decreased spinal cord

    blood flow, ischemic

    cell death

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    Anesthetic management acute

    SCI Airway evaluation

    Neurologic evaluation

    Pulmonary evaluation

    Cardiac evaluation and resuscitation

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    Neurologic Deterioration

    Associated with Airway

    Management in a Cervical Spine-Injured Patient

    Hastings RH, Kelly SD

    Anesthesiology vol 78:580, 1993

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    Details Unrecognized C-

    spine injury

    Pt becamequadriplegic after

    mask ventilation,

    repeated

    laryngoscopy andeventually

    cricothyroidotmy

    Hastings,Anesthesiology 1993

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    Use of the Intubating LMA-

    Fastrach in 254 Patients withDifficult to Manage Airways

    Ferson DZ, Rosenblatt WH, Osborn I,

    Ovassapian A.

    Anesthesiology 2001 vol 95:1175

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    Patients with Immobilized

    Cervical Spines 70 cases

    67 under general

    anesthesia

    2 awake/topicalized

    1 unconscious

    No new neurologic

    deficits

    Ferson et al,

    Anesthesiology 2001

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    Cervical spine motion: a fluoroscopic

    comparison during intubation with

    lighted stylet,GlideScope, andMacintosh laryngoscope.

    Turkstra et al.

    Anesth Analg 2005; 101: 9105

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    Tracheal intubation in patients with

    cervical spine immobilization:

    a comparison of the Airwayscope, LMA

    CTrach, and the

    Macintosh laryngoscopes

    M. A. Malik, R. Subramaniam, S.

    Churasia1,C. H. Maharaj, B. H. Harteland J. G. Laffey

    BJA 2009

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    Cervical Disc: Airway

    Strategies Talk to patient

    H/O extremity

    weakness/tingling

    Elicited symptoms

    with movement

    Neutral position isbest

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    Conditions associated with risk

    of cervical spine pathology

    Downs syndrome

    Rheumatoid arthritis

    Ankylosing spondylitis

    Psoriatic arthritis

    Trauma

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    On the Incidence, Cause, andPrevention of Recurrent Laryngeal

    Nerve Palsies During Anterior CervicalSpine Surgery

    Apfelbaum RI, et al: Spine Volume 25(22), 15 November 2000, pp 2906-2912

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    Laterality Right > Left

    Levels Lower Cervical Level

    Multiple Levels More Level Higher Incidence

    ETT Pressure Higher Pressure or Failure to Deflate

    FactorLeading To Possible Higher

    Incidence of RLN Injury

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    Risk Factors for Postoperative

    Airway Compromise

    Duration of surgery

    Amount of blood transfusion

    Obesity, airway pressure

    Operations of greater than 4 cervicallevels or involving C2

    Epstein NE. J Neurosurg

    94:185 2001

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    AnestheticT

    echnique Supine induction

    Maintenance with any

    combination ofopioids, muscle

    relaxants, volatile

    agents

    Careful prone

    positioning

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    Thorocolumbar Spine Disease Anterior or lateral

    pathology

    Multiple spinesegments

    Scoliosis, tumors,traumatic fractures

    Potential largeintraoperative bloodloss

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    Methods of Reducing Blood Loss

    and Limiting Homologous

    Transfusions

    Proper positioning to reduce intraabdominal

    pressure

    Surgical hemostasis

    Deliberate hemodilution (?)

    Preoperative donation of autologous blood

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    Prone Position Restriction of

    diaphragm

    by abdominal contents and weight of pt

    against thorax

    Create restrictivedefect

    Increased peakinspiratory pressure(barotrauma)

    Obstruction of Inf

    Vena Cava

    Decreases preload Increases perivertebral

    venous pressure

    (prone may improve

    oxygenation whenabdomen hangs free-

    chest roll or frame)

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    Prone Position Surgery Despite induced hypotension, some patients

    continue to bleed

    Pressure on the abdominal contents may be

    transmitted to the inferior vena cava and to

    the epidural venous system, causing

    increased bleeding

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    Flexed Prone Position Brachial plexus may be

    stretched

    Ulnar nerve not properly

    padded

    Eye damage from pressure

    Nose pressure

    Excessive compression to

    inferior vena cava(minimized by paddingunder inf iliac spine andchest rolls)

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    The Effect of Patient

    Positioning on Intraabdominal

    Pressure and Blood Loss inSpinal Surgery

    CKPark

    Anesth Analg 2000;91:552

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    Wilson Frame Maintains flexed

    position for spinal

    surgery Intrabdominal

    pressure may be

    increased if supporting

    pads are not properlyplaced

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    Blood loss during spinal surgery Group 1

    Blood loss (ml) 878

    # of patientstransfused = 5

    Fluid replacement

    2175 ml

    Operating time (min)

    136

    Group 2

    Blood loss (ml) 436

    # of patientstransfused = 1

    Fluid replacement1865 ml

    Operating time (min)134

    Park Anesth Analg 2000;91

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    Conclusions

    IAP and intraoperative blood loss were less

    in the wide vs. narrow width of the Wilson

    frame

    Blood loss per vertebra tended to increase

    with an increase in IAP in the narrow pad

    support

    Park Anesth Analg 2000;91

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    Jackson

    Table

    Frame based table

    Allows abdomen and

    chest to hang freely May allow 180 degree

    rotation

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    Lumbar spine surgery Preoperative

    pain/disability

    Intraoperativepositioning

    Anesthetic technique

    Blood loss

    Postoperative pain

    management

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    Support Devices Head & Neck

    44

    Surgical pillow/ foam

    donut,C-shaped face

    piece, horseshoe head

    rest, Prone Positioner,

    Prone View Helmet. C-Shaped Face Piece

    Horseshoe Head Rest Mayfield Tongs

    Mayfield tongs: moststable; recommended

    in cervical disc disease

    Prone Positioner

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    Ischemic Optic Neuropathy Rare but increasing

    Decreased perfusion

    Increased venouspressure

    Increased external

    pressure

    Decreased oxygen

    carrying capacity

    Williams, et al. Anesth Analg 1995 80:1018

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    Injuries:E

    ye

    46

    Corneal abrasions

    Orbital edema

    Postoperative visual loss ( POVL)

    Rare; unclear etiology

    ASA Closed Claims Project 12 : management of

    anesthesiologists frequently implicated

    ASA Professional Liability Committee created the

    POVL Registry 13 in 1999

    12ASA Closed Claims Project http://www.asaclosedclaims.org/13American Society of Anesthesiologists Task Force on Perioperative Blindness: Practice advisory for perioperative

    visual loss associated with spine surgery: a report by the American Society

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    POVL Registry

    47

    SPINE 72%

    Distribution of cases from the

    ASA POVL Registry

    Goal: Identify risk factors associated with POVL

    Retrospective analysis of patients who reported visual loss < 7

    days postop

    PION 60%AION 20%

    Distribution of 93 ophthalmic lesions

    associated with POVL after spine surgery

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    POVL

    48

    Ischemic Optic

    Neuropathy (ION)

    Central Retinal Artery

    Occlusion (CRAO)

    Etiology Intraop BP

    Prolonged surgery

    Blood loss Crystalloid infusion

    Direct external pressure

    Emboli

    Mechanism Ischemia

    Orbital edema stretch

    and compression of ON

    Ocular perfusion pressure

    ClinicalFeatures

    PainlessBilateral

    Light perception

    Visual fields

    PainlessUnilateral

    Periorbital swelling or

    ecchymosis

    ASA Closed Claims Project

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    ASA Closed Claims Project

    Profound visual loss

    Vision loss is usually

    unilateral. Vision loss is

    usually total.

    Visual loss in spine

    surgeries

    85% Ischemic Optic

    Neuropathy (ION)

    11% Central retinal artery

    occlusion (CRAO)

    4% Other Diagnoses

    www.asaclosedclaims.orOverview

    Pain Management

    Major Risks

    Equipment

    MAC

    Visual Loss

    Medication

    Premiums

    ASA Closed Claims Project

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    ASA Closed Claims Project

    Visual loss in spine

    surgeries

    85% Ischemic Optic

    Neuropathy (ION)

    11% Central retinal artery

    occlusion (CRAO)

    4% Other Diagnoses

    CRAO can result from

    pressure on the globe.

    www.asaclosedclaims.orOverview

    Pain Management

    Major Risks

    Equipment

    MAC

    Visual Loss

    Medication

    Premiums

    ASA Closed Claims Project

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    ASA Closed Claims Project

    Over two-thirds of

    cases reported to the

    POVL Registry wererelated to spine

    surgery in the prone

    position.Lee LA, et al. The American Society of Anesthesiologist Postoperative

    VisualLoss Registry: Analysis of 93 Spine Surgery Cases with

    Postoperative VisualLoss. Anesthesiology. 2006 Oct; in press.

    www.asaclosedclaims.orOverview

    Pain Management

    Major Risks

    Equipment

    MAC

    Visual Loss

    Medication

    Premiums

    ASA Closed Claims Project

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    ASA Closed Claims Project

    Ischemic opticneuropathy was the

    most common (89%)

    cause ofvisual loss

    after spine surgery in

    the prone position.

    www.asaclosedclaims.orOverview

    Pain Management

    Major Risks

    Equipment

    MAC

    Visual Loss

    Medication

    Premiums

    Lee LA, et al. The American Society of Anesthesiologist Postoperative

    VisualLoss Registry: Analysis of 93 Spine Surgery Cases with

    Postoperative VisualLoss. Anesthesiology. 2006 Oct; in press.

    ASA Closed Claims Project

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    ASA Closed Claims Project

    1000 ml estimated

    blood loss

    6 hours anesthetic

    duration

    www.asaclosedclaims.orOverview

    Pain Management

    Major Risks

    Equipment

    MAC

    Visual Loss

    Medication

    Premiums

    Lee LA, et al. The American Society of Anesthesiologist Postoperative

    VisualLoss Registry: Analysis of 93 Spine Surgery Cases with

    Postoperative VisualLoss. Anesthesiology. 2006 Oct; in press.

    In 96% of prone positionspine cases, at least one of

    the following was present:

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    Postoperative Vision Loss-

    Risk Factors Atherosclerotic disease

    Hypotension Anemia

    Excessive blood loss

    Long duration of surgery Head dependent positioning

    Cheng MA Neurosurgery

    46:625, 2000

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    Cardiovascular Support

    Maintain MAP above 70 mmHg

    Fluid management-blood & crystalloid

    Pressors if needed

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    Spine Surgery- Monitoring

    Routine

    Arterial line

    CVP/ PA catheter

    Neurophysiologic

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    Monitoring the Spinal Cord

    SSEP

    MEP

    Wake up test

    EMG

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    Indications for SSEPs

    Spinal

    instrumentation

    Scoliosis correction Spinal cord

    operations

    Aortic surgery

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    Spine surgery: Times of

    Increased Risk

    Spinal distraction

    Sublaminar wiring

    Induced hypotension

    Inadvertent cord compression

    Certain instrumentation (Lugue rods)

    Ligation of segmental arteries

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    Dorsal /

    Posterior

    Ventral /

    Anterior

    MEP

    MEP

    SSEP

    SSEP

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    Damage in the territory of the anterior

    spinal artery might theoretically occur

    without causing significant impairment ofthe dorsal sensory tracts, particularly when

    the spine is approached from the anterior

    side.May DM, Jones SJ,Crockard HA.

    Somatosensory evoked potential monitoring in cervical surgery:

    identification of pre- and intraoperative risk factors associated with neurological deterioration.

    JNeurosurg1996;85:5667

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    SSEP

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    Loss of SSEP & MEP

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    Caveats for MEP monitoring

    You CAN intubate

    with non-depolarizing

    agent (there will betime for it to wear off)

    When closing,

    administer NMB to

    allow decrease ofhypnotic agents

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    Anesthetic Considerations

    Patients often on chronic pain medication

    Hypotension may occur with acute blood loss

    Dexmedetomidine

    Use perioperatively

    May decrease narcotic use Hemodynamic stability

    Patients comfortable postoperatively

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    Pain management strategies

    IV PCA

    Multimodal therapy

    Epidural opioids(catheter placed by

    surgeon)

    Cooperation with pain

    service

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    Lumbar spine surgery

    Performed by

    neurosurgeons and

    orthopedics Minimally invasive

    techniques

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    The ProSeal laryngeal mask airway in

    prone patients: a retrospective audit of

    245 patients

    Patients positioned prone for induction

    Mask ventilation followed prone insertion Digital insertion in 237 pts,GEB technique

    in 8 pts

    No complications- ONLY for experienced

    practitioners!

    Anesth Intensive Care

    2007:35

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    Caveats for prone LMAs

    Have good technique

    Avoid light anesthesia

    Position carefully andconfirm placement

    tests

    Have stretcher

    available (just in

    case!)

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    Conclusions

    Understand and appreciate the anatomy and

    physiology of the spinal cord

    Communicate with your surgeons

    Explore new techniques but remember to

    perfuse and monitor the patient