ACHIEVEMENT REWARDS FOR COLLEGE SCIENTISTS

SCHOLAR DIRECTORY2012-2013

SAN DIEGO CHAPTER

ARCS® Foundation, Inc.AT A GLANCE

ARCS - Achievement Rewards for College Scientists.A Scholar must be a U.S. citizen and must maintain a 3.5 GPA.

A Scholar must be enrolled as a full-time graduate student specializing in science, engineering or medical research. ARCS Foundation raises money to provide awards to students studying at SDSU, TSRI, UCSD, and USD.

The individual university selects academically outstanding students who demonstrate exceptional promise of makingcontributions to the advancement of science, and to the material and intellectual welfare of all people.

Awards are not need-based and are for the discretionary use of the Scholar.ARCS Foundation is a national 501(c)(3) nonprofit organization.

ARCS Foundation is an all-volunteer women’s organization.100% of every dollar donated goes to Scholar Awards.

Since 1985, the San Diego Chapter has awarded $7,584,500 in 1023 awards to 486 individual Scholars.

ARCS Foundation, Inc., San Diego Chapter Board of Directors

2012-2013

President . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .Robin LubyPresident-Elect . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .Diane Chalmers

Vice PresidentsAdministration . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .Mary FitzCommunications . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .Marti ShowleyFund Development . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .Sharon ArbelaezMembership . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .Maureen LambertiMembership Operations . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .Lois ThompsonSpecial Events . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .Joy FryeUniversity Relations . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .Diane Chalmers

Recording Secretary . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .Helga MooreCorresponding Secretary . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .Kim JohnsonTreasurer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .Marcia BorgmanAssistant Treasurers

Operations . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .Ann DynesDonations . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .Christine Gutheil

DirectorsBusiness Giving . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .Patty FullerFoundation Giving . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .Carolyn WaggonerMember Giving . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .Jeanne LarsonMeetings and Properties . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .Virginia ChaseyPublications . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .Mary Lou QuickStrategic Planning . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .Holli GarrettWeb Site . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .Toni Nickell

Community Advisory Council Liaison . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .Joan EvangelouParliamentarian . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .Nancy Bildsoe

Special ChairsDatabase . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .Andy CorrentiEditing . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .Nancy Bildsoe, Lois Thompson, Toni Nickell, Robin LubyHistorian . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .Adrienne McCulloughMailing . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .Connie AdelmanNew Members . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .Karen LudwigPublic Relations . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .Darlene DaviesRoster . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .Mary Lou Quick, Toni NickellScholar Recognition Event . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .Virginia ChaseyScientist of the Year Dinner . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .TBD

University LiaisonsSDSU . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .Barbara HartungTSRI . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .Toni NickellUCSD . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .Priscilla MoxleyUSD . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .Deborah Mandabach

Our MissionARCS Foundation advances science and technology in the United States by providing financial awards to

academically outstanding U.S. citizens studying to complete degrees in science, engineering and medical research.

About ARCSARCS® Foundation, Inc.—Achievement Awards for College Scientists—is a distinguished national nonprofit volunteerwomen’s organization consisting of 17 geographically diverse, autonomous chapters committed to a commonmission and operating under the auspices of a national board. Through partnerships with 55 of America’s most highlyranked universities, ARCS Foundation provides financial awards to those U.S. undergraduate and graduate studentsjudged to be most capable of innovative research in science, engineering and medical research. Our Scholar Awardmodel provides flexible and unrestricted funding that is often a game changer for these fledgling researchers. It isuniquely structured to support scientific advancement by supporting individual potential.

The Foundation was formed by a small group of women in Los Angeles in 1958 in response to the Russian launch ofSputnik and the need to spur U. S. supremacy in the technology race. Over the 54-year history of ARCS Foundation,the Chapters across the country have provided 14,188 Scholar Awards totaling $82,828,057.

One hundred percent of scholar award contributions—from corporations, endowments, individuals,foundations, members of ARCS® Foundation and unsolicited gifts of money designated

for Chapters’ Scholar Funds—goes to fund these motivated students.

Since the San Diego chapter began in l985, 1,023 Scholar Awards totaling $7,584,500 have been awarded to graduateand undergraduate students attending San Diego State University, The Scripps Research Institute, University ofCalifornia, San Diego, including Scripps Institution of Oceanography, and University of San Diego.

About the ScholarsThe San Diego Chapter ofARCS Foundation is proud tointroduce our 2012-2013 ARCSScholars. This year the SanDiego Chapter awarded$397,500 to 57 ARCSFoundation Scholars: 12Scholars from San Diego StateUniversity; 8 from The ScrippsResearch Institute; 31 fromUniversity of California, SanDiego; and 6 from Universityof San Diego.

These merit Scholars repre-sent America’s future. Wewelcome them as they join theranks of outstanding scientistsand engineers who are contri-buting to the advancement ofscience and technology and to keeping the U.S. competitive throughout the world.

San Diego Arcs Foundation Scholars pursue Undergraduate and Graduate degrees in a wide range of subjects.Beyond the generalized area of science, engineering, and medical research, these Scholars are specializing inastronomy, biochemistry, botany, cell and molecular biology, chemistry, computer science, ecology, engineeringgenetics, marine biology, mathematics, oceanography, physics and many more.

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2012-2013 Community Advisory CouncilThe purpose of ARCS® Foundation, Inc. San Diego Chapter Community Advisory Council (CAC) is to assist the

organization in achieving their mission. The CAC is composed of distinguished professionals drawn from diversescience and technology industries represented in San Diego. Through the members of the Council, the chapter has

access to a larger network of individuals, businesses and professional organizations interested in the advancement ofscience and technology. They help the chapter accomplish its goals, promote activities and facilitate fundraising. Forthe ARCS Scholar, the Council organizes activities that enrich the Scholars’ professional experience and serves as a

bridge to the entrepreneurial community. We thank them for their continued support.

June Chocheles, President, Chocheles Consulting GroupChairman

Duane Roth, CEO, CONNECTHonorary Chairman

Shirley Adams, Vice President, Director Information Technology, General DynamicsJon Berg-Johnsen, Corporate Business Development, Lockheed Martin Corporation

Katie Collins, Director of Development, J. Craig Venter InstituteLynn Congemi, Vice President, SAIC

Maria Fischer, CEO, Bien Tech InternationalPatricia Fuller, Consultant, Fuller Communications

Ken Garcia, New Professionals Group & Organizational Development Systems Center, SPAWARHolli Garrett, President, Clean Energy Principles

Andrew Hewitt, President, Manhattan Renewable EnergyPat Kelly, AFCEA Educational Committee Chair, Vice President, Sonalysts,

Diane Klotz, Director/Office of Training and Academic Services, Sanford Burnham Medical Research InstituteJennifer Landress, CMP, Senior Vice President & Chief Operating Officer, BIOCOM

Terry Magee, Executive Vice President, Wavestream CorporationTerrance J. McKearney, President, The Ranger Group

Terry Moore, Chairman & Founder, The VC Roundtable, Managing Partner, Moore Venture Partners LPJoseph Panetta, President & CEO, BIOCOM

Nancy Pearson, Director of Engineering, Northrop Grumman Information SystemsLisa Petrillo, Communications Specialist, Energy and Advanced Concepts, General Atomics

James Rohr, Educational Outreach Coordinator, SPAWAR Systems CenterJohn Schierer, Corporate Vice President, Human Resources, Cubic Corporation

Ann Siemens, Principal, Siemens & Associates, Inc.Roger Webb, President, TVA Networks, Inc.

Karen Winston, Vice President, Programs, CONNECT

Our Community Supporters“Cymer’s support of ARCS and the talented graduate students at SanDiego’s outstanding academic institutions aligns well with our vision tocreate innovative technology that makes the world a better place to live.We are proud to be associated with a very worthy cause, and look forwardto seeing ARCS scholars make a significant mark in their fields of interest.” BLAKE MILLER, Vice President, MarketingCymer, Inc.

“Union Bank is proud to be associated with ARCS for over 10 years inproviding scholarship opportunities to academically excellent students.Recognition of significant achievement in promoting the educationalmission and vision of the ARCS scholars aligns with the Union Bankstrategic mission.” MARLA BLACK, Senior Vice PresidentUnion Bank

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“We're extremely grateful to the ARCS Foundation for theirpartnership and support of our students. Working together, we canhelp develop the scientists and engineers who will lead ourcountry's future scientific and economic development.”

Elliot Hirschman, PresidentSan Diego State University

“The importance of attracting the brightest students into advancedgraduate programs in science cannot be underestimated. We aregrateful to ARCS Foundation for its support of our students inKellogg School of Science and Technology who demonstrate bothacademic excellence and passion for biomedical research. ARCSFoundation support for students at Scripps Research since 1997 hashad great impact, and we are honored to continue that partnershipto develop the scientific leaders of the twenty-first century. ARCSScholar awards provided to Scripps Research are essential to theultimate success of these talented students and their quest tobecome leaders in industrial and government laboratories, thusadvancing discovery and technology in the United States.”

Michael Marletta, PresidentThe Scripps Research Institute

“At UC San Diego, we appreciate the generous support of ARCSFoundation, which provides Scholar awards for our graduate anddoctoral students conducting research in the sciences, engineeringand medical fields. Together, we are educating our future leaders sothey can go on to greatly impact our community, nation and worldthrough their discoveries and innovations.”

Pradeep K. Khosla, ChancellorUniversity of California, San Diego

“Your generosity promotes the University of San Diego’s mission tooffer motivated and capable students superb science and health careeducation. The philanthropy of ARCS is a gift to the entire communityby providing it with science and health care professionals.”

Mary E. Lyons, PresidentUniversity of San Diego

Words from University Presidents

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Ways to Help ARCS Foundation Scholars100% of each contribution is awarded directly to the Scholar.

ARCS Foundation provides a unique vehicle for supporting Scholars in science, medicine, and engineeringwithout incurring administrative overhead. Member dues and event underwriting cover all operating expenses.Members who donate their time provide all administrative services.

There are two ways to support ARCS Scholars studying to complete their degrees in science, medicine, andengineering. The first is to make an annual gift to the Scholar Award Fund. The entire amount is awarded within ayear of receipt. The second way to support Scholars is through a gift to the Endowment Fund. The principalcontinues to accrue interest in perpetuity; Scholar Awards are made from the interest.

I. Annual Gifts to the Scholar Award FundGifts to ARCS Foundation Scholar Award Fund support continuing and new Scholars at San Diego StateUniversity, The Scripps Research Institute, University of California, San Diego, and University of San Diego.Gifts to the Scholar Award Fund may be made by check, credit card, or through gifts of appreciatedsecurities. Gifts received during the fiscal year (July 1 - June 30) are awarded at the beginning of thefollowing academic year.

II. Gifts to ARCS Foundation Endowment Fund Gifts to ARCS Foundation Endowment build an investment fund, the earnings of which provide a permanentsource of income essential for supporting a portion of the Award Fund in perpetuity. Whenever anEndowment grows by $150,000, the interest earned generates a $7,500 Award. The Virginia L. Grady Fund,Wally Schirra Memorial Endowment Fund and the ARCS Endowment Fund are examples of permanentlyendowed Scholar Awards.

ARCS Legacy Society: ARCS Legacy Society comprises donors who have provided for ARCS Foundation intheir estate plans, thereby insuring the future of ARCS Scholars. For further information about how tobecome a member of the Legacy Society, contact Marti Panarisi at (858) 756-9572.

Memorial & Honorary Gifts: Gifts may be made in memory of a loved one, or in recognition of anindividual on the occasion of a birthday, anniversary, or special event. All memorials and honorariahelp build the Endowment.

TO GIVE ONLINE:Go to the ARCS website: www.arcsfoundation.org/san_diego

Click the turquoise “Donate” button found at the bottom of this homepage. Then click the blue “Donate Now” button found at the bottom of the linked page.

FOR MORE INFORMATION, PLEASE CONTACT:

Robin Luby | President rbluby@earthlink.net | (858) 459-9455

or Sharon Arbelaez | Vice President, Fund Development

sjarbelaez@hotmail.com | (858) 452-6541

ARCS Foundation, Inc.San Diego Chapter

P.O. Box 8394, Rancho Santa Fe, CA 92067-8394sandiego@arcsfoundation.org--emailwww.arcsfoundation.org/san_diego

A Nonprofit Charitable Organization | Federal I.D. No. 33-0164533 | Corporate No. 1367672

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ARCS® Foundation, Inc., San Diego ChapterMAJOR DONORS

Cumulative Gifts 1985 through June 2012

STELLAR BENEFACTORS – $1,000,000 AND ABOVEThe Reuben H. Fleet Foundation Fund

Virginia Lynch Grady

GALAXY BENEFACTOR – $500,000 AND ABOVEThe Donald C. & Elizabeth M. Dickinson Foundation

ALBERT EINSTEIN PATRON – $250,000 - $499,999Blasker-Rose-Miah Fund

International Systems, LLC/Allan Wegner and Bob Whalen

THOMAS EDISON PATRON – $100,000 - $249,999

MARIE CURIE CIRCLE – $50,000 - $99,999

GALILEO CIRCLE – $25,000 - $49,999

The Thomas C. Ackerman FoundationThe Beyster Family Foundation

The Favrot FundKathryn Crippen Hattox Fund

The Legler Benbough FoundationDale & Marge Myers Fund

Margaret L. RouletteEllen Browning Scripps Foundation

Timkin-Sturgis FoundationUnion Bank

WD-40 Company

The Atkinson Family FoundationEmily Bagnall

Karen & Bob Bowden/Bowden Family FoundationCubic Corporation

Cymer, Inc.Dr. Charles C. & Sue K. Edwards Foundation

Cecil & Ida Green FoundationJack Heckel

Hervey Family Non-endowment Fund

Jackie LeiszMaurice J. Masserini Charitable Trust

The Collins Companies Foundation/Diane & Tyler MillerThe Parker Foundation

Pfizer La JollaScience Applications International Corporation (SAIC)

Pat & Bob WhalenBetty Jo & Hal Williams

Carlos & Sharon ArbelaezCharles & Ruth Billingsley Foundation

The Burnham FoundationConexant Systems, Incorporated

The Education Financing Foundation of CaliforniaBecki & Ed Etess

Samuel H. French III & Katherine Weaver French FundConnie K. Golden

The Heller Foundation of San DiegoJanet & Dan La Marche

Richard G. Lambert M.D. Foundation for EducationDr. & Mrs. William McColl

Nancy & Bill NorgrenOak Industries

Thomas & Audrey Pine FoundationMrs. Walter J. Podbielniak

The George Smedes Poyner FoundationMrs. Donald Roon/Roon Foundation, Inc.

Marti & Larry ShowleyLois S. Thompson

The Thursday Club FoundationTitan Corporation

The Robert G. & Gloria R. Wallace FamilyWells Fargo Bank

Our greatest gratitude to these major donors who have made a significant contribution to the future of science, engineering and medicine by supporting ARCS Scholars.

=The San Diego Foundation

= Fund Managed by Union Bank

The above amounts include donations to the ARCS Scholarship and Endowment Funds.

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ARCS® Scholars 2012-2013$7,500 Graduate Scholar Awards: 46$5,000 Graduate Scholar Awards: 8

$5,000 Undergraduate Scholar Awards: 2$2,500 Undergraduate Scholar Award: 1 (half a year)

NAME DEGREE AREA OF CONCENTRATION SPECIALIZATION

Martis Cowles Ph.D. Cell & Molecular Biology Stem Cells, Neurodegenerative Disease

Charles Granger M.S. Physics Electro-Optics

Michael Gurney Ph.D. Cell and Molecular Biology Autophagy, Inflammation

Marcel Hetu Ph.D. Analytical Chemistry Cancer, Alzheimer's Disease

Manna Iwabuchi Ph.D. Analytical Chemistry Parkinson's Disease, Disease Detection

Pearl Quijada Ph.D. Cell & Molecular Biology Stem Cells, Heart Injury

Chelsea Rochman Ph.D. Ecology Plastics, Pollution Detection

John Ruedas Ph.D. Cell & Molecular Biology Understanding Lethal Viruses

Lucie Nguyen Sharpsten Ph.D. Computational Science Statistics, Glaucoma

Ginger Tsueng Ph.D. Cell & Molecular Biology Coxsackievirus, Immune System

Stan Walls Ph.D. Cell & Molecular Biology Saturated Fats

Robert Wilson Ph.D. Inorganic Chemistry Synthesis, X-ray Diffraction

Jessica Bruhn-Johannsen Ph.D. Structural Biology Henipavirus, Innate Immune Response

Katharine Duncan Ph.D. Organic Chemistry Pain Relief, Stroke, Marijuana

Laurie Gay Ph.D. Chemical & Biological Sciences Cancer, Blood

Sarah LeBoeuf Ph.D. Biological Sciences Cancer Biology

Joseph Nagano Ph.D. Chemistry Drug-Like Molecules, Better Therapeutics

Aaron Sather Ph.D. Organic Chemistry Uranium, Purifying Water

Joshua Silverman Ph.D. Biophysics Cell Growth

John Tat Ph.D. Cell & Molecular Biology Cell Cycle Regulation, Cancer Therapeutics

Thanks to our DonorsThe San Diego Chapter of ARCS Foundation, Inc. gratefully acknowledges the

members and donors who volunteer their time and give generously of their

resources. Without their understanding of the importance of planting trees (growing

Scholars), we could not celebrate these 57 outstanding individuals.

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NAME DEGREE AREA OF CONCENTRATION SPECIALIZATION

Jessica Buckley B.A./B.S. Mechanical Engineering Machines, Industry

Elizabeth Light Ph.D. Nursing Science Maternal-Child Health, Reproductive Health

Connor Lind B.A./B.S. Mechanical Engineering International Development

Catherina Madani Ph.D. Nursing Science Palliative Care, Pulmonary Hypertension

Tawni Paradise B.A./B.S. Engineering Engineering

Christine Sloan Ph.D. Nursing Science Palliative Care, Pediatric Patients

Rebecca Asch Ph.D. Biological Oceanography Climate Impacts on Fisheries

Aereas Aung Ph.D. Cellular Mechanics Muscle Development

Patrick Blachly Ph.D. Physical Chemistry Computer-Aided Drug Design

Jordan Carlson Ph.D. Health Behavior Science Physical Activity

Phillip Compeau Ph.D. Mathematics Genome Rearrangements, BioinformaticsEducation

Casey Conger Ph.D. Physics Universe Development

Laura Connelly Ph.D. Materials Science & Engineering Alzheimer's Disease

Chris DeBoever Ph.D. Genetics and Genomics Cancer Genomics

Russ DeKelver Ph.D. Cell & Molecular Biology Cancer, Blood Cell Development

Jennifer Emond Ph.D. Public Health Nutrition Breast Cancer

Kathleen Fitzpatrick Ph.D. Biomedical Sciences HIV, Immune System

Wes Gifford M.D./Ph.D. Neuroscience Neurodegeneration, Neurodevelopment, NextGen Sequencing

Erilynn Heinrichsen Ph.D. Biomedical Science Metabolism, Hypoxia

Stephanie Huelga Ph.D. Bioinformatics & Systems Biology RNA Processing

Katie LeVan Ph.D. Biological Sciences Ecological Effects of Invasive Species

Cameron Nowzari Ph.D. Mechanical Engineering Robotic Networks, Self-Triggered Control

Morgan Nunn Ph.D. Chemistry Water, Solar System

Jason Oberg Ph.D. Computer Science Hardware Security

Matthew Ondeck Ph.D. Materials Science & Engineering Cell Substrate Stiffness

Gabriel Reyes-Rodríguez Ph.D. Organic Chemistry Structure, Mechanism, and Reactivity

Kate Rogers Ph.D. Biomedical Sciences Pharmacology, Drug Discovery

Janelle Shane Ph.D. Electrical Engineering Photonics, Imaging

Lauren Shipp Ph.D. Marine Biology Embryonic Development, Toxicology

Matthew Bronson de Stadler Ph.D. Engineering Science Turbulence, Numerical Simulation

Ludovic Vincent Ph.D. Bioengineering Stem Cell Environment

Katherine Walsh Ph.D. Mathematics Knot Theory

Spencer Wei Ph.D. Biomedical Sciences Breast Tumors, Cancer Types

Daniel Whisler Ph.D. Structural Engineering Blast, Composites, FEA

Matthew Wingert Ph.D. Mechanical Engineering Nanomaterials, Energy Transport

Jennifer Young Ph.D. Bioengineering Tissue Stiffness, Stem Cells

David Zimmermann Ph.D. Mathematics Functional Analysis

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REBECCA ASCHUniversity of California, San DiegoScripps Institution of Oceanography

Degrees:M.S. in Oceanography, University of Rhode IslandB.A. in Anthropology, Smith College

Scholar Sponsors:Hervey Family Non-endowment Fund

About the Scholar:Rebecca is investigating changes in the seasonal timing ofwhen 43 fish species spawn, using a unique dataset that hassurveyed California waters over the past 60 years. Climatechange is modifying seasonal patterns of ecosystems aroundthe world, leading to the earlier onset of spring conditions anda delayed start of fall. Fish production is affected by thetemporal coincidence between spawning and upwelling, whichresults in enhanced primary production. When there is amismatch between these events, young-of-year fish mayexhibit lower survival and growth. Rebecca enjoys hiking, yoga, reading, and making jewelry.

Benefits to Society:Of the 43 fish species examined by Rebecca, 11 are commer-cially important to fisheries with a combined value of $31.6million for ex-vessel landings. Other fish species areecologically important because they serve as prey forendangered and threatened species of marine mammals andseabirds. One way through which climate change may impactthese fishes is by altering the seasonal timing of spawning.Many fishes have evolved to spawn when spring temperaturessurpass a certain level. The timing of spawning often coincideswith periods when there is an abundant supply of plankton tofeed the offspring of fishes. During some years, there is amismatch in these events, in which fishes spawn either beforeor after the abundance of plankton peaks. During those years,the survival of young fishes is often poor, negatively affectingthe viability of fisheries. Since each species of plankton and fishmay respond differently to climate change, global warmingcould lead to increased mismatches between the timing of fishreproduction and plankton blooms, with negativeconsequences for communities that depend on fisheries.

Awards and Honors:California Sea GrantDr. Nancy Foster ScholarshipJoint Trawl AwardJohn A. Knauss Marine Policy FellowshipMacMillan Fellowship in Fisheries OceanographySally Richardson Award for Best Student Presentation

Publications and Posters:Davison, P.; Asch, R.G. Plastic ingestion by mesopelagic fishesin the North Pacific Subtropical Gyre. Marine Ecology ProgressSeries 2011, 432, 173-180.

Checkley Jr., D.M.; Dickson, A.G.; Takahashi, M.; Radich, J.A.;Eisenkolb, N.; Asch, R. Elevated CO2 enhances otolith growth inyoung fish. Science 2009, 324, 1683.

AEREAS AUNGUniversity of California, San DiegoJacobs School of Engineering

Degrees:B.S. in Bioengineering, University ofCalifornia, San Diego

Scholar Sponsors:The Jerry D. and Cheryl Sawatzke Routh FamilyFoundation

About the Scholar:Aereas is researching the role of cell-matrix interactions duringthe differentiation of stem cells. Improved understanding of this“mechano-biology” of stem cells will establish an addeddimension which also must be accounted for to better harnessthe regenerative potential of stem cells. Aereas enjoys readingand listening to music and he would like to learn how to playthe violin.

Benefits to Society:By initially understanding the fusion process between muscleprecursor cells, we can gain insight into how the naturalprocess of muscle development should occur. This will serve asa strong foundation to further understand muscle homeostasis,cell-transplantation-based repair and regeneration, anddegenerative diseases by varying the cell types that areanalyzed with this method. In this manner, we can, in thefuture, comprehend how diseased or aged muscle cells deviatefrom the natural fusion process, giving immeasurable clinicalinsights into the restoration or maintenance of muscle health.

Awards and Honors:Robert C. Byrd Scholarship

REU Summer Research Award

Summer Research Scholarship, California Institute of Technology

Tau Beta Pi

Publications and Posters:Aung, A.; Gupta, G.; Ghassemian, M.; Varghese, S.Osteoarthritic chondrocyte-secreted morphogens inducechondrogenic differentiation of human mesenchymal stemcells. Arthritis and Rheumatism 2011, 63, 148-158.

Ayala, R.; Zhang, C.; Yang, D.; Aung, A.; Hwang, Y.S.; Shroff,S.S.; Arce, F.T.; Lal, R.; Arya, G.; Varghese, S. Engineering thecell-material interface for controlling stem cell adhesion,migration, and differentiation. Biomaterials 2011, 32, 3700-3711.

Lim, H.L.; Chuang, J.C.; Tran, T.; Aung, A.; Arya, G.; Varghese, S.Dynamic Electromechanical Hydrogel Matrices for Stem CellCulture. Advanced Functional Materials 2010, 21, 55-63.

Zhang, C.; Aung, A.; Liao, L.; and Varghese, S. A novel singleprecursor-based biodegradable hydrogel with enhancedmechanical properties. Soft Matter 2009, 5, 3831-3834.

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PATRICK BLACHLYUniversity of California, San DiegoPhysical Sciences

Degrees:M.S. in Chemistry, University ofCalifornia, San DiegoB.A. in Chemistry, Grinnell College

Scholar Sponsors:The Donald C. & Elizabeth M. Dickinson Foundation

About the Scholar:Pat is investigating a protein vital to the survival of malaria-causing parasites. By understanding the structure of thisprotein, small molecules can be designed that are able to bindto the drug target. The atoms that comprise the small moleculeare chosen to optimally interact with specific atoms on thetarget protein. This work can be done in collaboration with cellbiologists to test whether the proposed drugs actually kill themalarial parasite. His computer-aided drug design cuts downthe time and efforts needed to predict the structures of drugsfor binding to a specific target. Pat enjoys water sports and hasplayed collegiate polo.

Benefits to Society:Broadly speaking, Pat’s research will help to improve theefficiency and accuracy of computational drug designprotocols, which in turn should help streamline the earlyphases of drug development. More specifically, Pat’s work intrying to develop inhibitors for proteins vital to the function ofmalarial-causing parasites and bacteria may help in thediscovery of potent anti-malarial and anti-bacterial drugs.

Awards and Honors:NIH Molecular Biophysics Training Grant

Publications and Posters:Blachly, P.G.; Francisco J.S. A theoretical study of reaction ofOH radicals with Cysteine and Homocysteine. J. Phys. Chem. A.(In Progress).

Williams, S.L.;* Blachly, P.G.;* McCammon, J.A. Measuring thesuccesses and deficiencies of constant pH moleculardynamics: A blind prediction study. Prot. Struct. Funct. Bioinf.2011. (In print). (* co-first authors)

Liessmann, M.; Hansmann, B.; Blachly, P.G.; Francisco, J.S,Abel, B. Primary steps in the reaction of OH radicals withbiomolecules at low temperatures: Perspectives fromexperiment and theory. J. Phys. Chem. A. 2009, 113, 7570-7575.

Blachly, P.G.; McCammon, J.A. Moving forward with constantpH molecular dynamics: Enhancing sampling with oscillatingaccelerated molecular dynamics, 2011 International Conferenceon Biophysics, La Jolla, CA.; June 2011.

Blachly P.G.; Hernandez-Soto, H. Theoretical study of thepropensities of magnesium and calcium silicates to act assurfaces, 237th American Chemical Society National Meeting,Salt Lake City, UT, March 2009.

JESSICA BRUHN-JOHANNSENThe Scripps Research InstituteKellogg School of Science and Technology

Degrees:B.A. in Biochemistry, Biophysics andMolecular Biology, Whitman College

Scholar Sponsors:Webster and Helen Kinnaird, Paul Bechtner Foundation

About the Scholar:Jessica’s research is in regard to the Hendra and Nipah virusinfections, which at this point have no therapeutics or vaccinesfor treatment and prevention, even though these viruses areamong the world’s most deadly. Determining the molecularmechanisms behind host-virus interactions is important tounderstanding the basic biology driving their virulence and inidentifying potential drug candidates. Finding a way to blockthe viral proteins bound to host factors can allow the immunesystem a chance to fight off the infection. Jessica enjoyssurfing, rock climbing and rafting.

Benefits to Society:Hendra and Nipah viruses are newly emergent pathogens withmortality rates as high as 90%. Part of what makes theseviruses so deadly is their ability to stop the immune systemfrom fighting off the infection. These viruses produce threerelated proteins that block the immune response. Jessica istrying to better understand how these proteins work bydetermining their three-dimensional structures. Informationprovided by these studies should help guide the developmentof much-needed antiviral therapeutics.

Awards and Honors:The Scripps Research Institute Dean's Fellowship

Delia and Donald Baxter Fellowship

Perry Research Award

American Chemical Society Award in Analytical Chemistry

Walter Brattain Scholarship

Publications and Posters:Correia, B.E.; Ban, Y.A.; Holmes, M.A.; Xu, H.; Ellingson, K.;Kraft, Z.; Carrico, C.; Boni, E.; Sather, D.N.; Zenobia, C.; Burke,K.Y.; Bradley-Hewitt, T.; Bruhn-Johannsen, J.F.; Kalyuzhniy, O.;Baker, D.; Strong, R.K.; Stamatatos, L.; Schief, W. Computationaldesign of epitope-scaffolds allows induction of antibodiesspecific for a poorly immunogenic HIV vaccine epitope.Structure. 2010, 18(9), 1116–26.

Correia, B.E.; Ban, Y.A.; Friend, D.J.; Ellingson, K.; Xu, C.; Boni,E.; Bradley-Hewitt, T.; Bruhn-Johannsen, J.F.; Stamatatos, L.;Strong, R.K.; Schief, W.R. Computational protein design usingflexible backbone remodeling and resurfacing: case studies instructure-based antigen design. J. Mol. Biol. 2011, 405(1), 284-97.

Bruhn, J.F. Creating a chimera: studying multiple sclerosisthrough a myelin basic protein-actin fusion protein. WhitmanCollege. 2009.

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JESSICA BUCKLEYUniversity of San DiegoEngineering Program

Scholar Sponsors:Bob & Pat Whalen

About the Scholar:Jessica is pursuing research that analyzes the kinematics andoptimization of straight-line mechanisms. The PeaucellierMechanism, the center of the study, turns rotational motioninto linear motion, necessarily creating a perfectly straight lineby its geometry. The goal of this research has been to createthe longest possible line at a relatively constant speed byvarying the ratio of link lengths that make up this mechanismand to observe the effects of changing its configuration. Thisproject will enable standards to be created of the size of themechanism based on the desired output motion, which will beuseful in situations requiring perfectly straight lines, such asprecision engine piston motion and guiding operationsperformed on a mechanized assembly line. In her spare time,Jessica enjoys sailing, windsurfing, and playing rugby.

Benefits to Society:With the constant drive to maximize production and efficiency,the natural goal of mechanism research is optimization: howcan smaller machines do more work as quickly as possibleand for as long as possible? By optimizing a mechanism suchas the Peaucellier Mechanism, industry standards can becreated to find the optimal relationships between mechanismparts and output stroke or line length. The PeaucellierMechanism is currently being used to guide pistons in somediesel engines, and assembly line production is another goodapplication of the mechanism: as parts move along aconveyor belt at a constant velocity, a properly optimizedPeaucellier Mechanism can guide other mechanisms tooperate on the parts at the same velocity. The use of an exactstraight-line mechanism is most beneficial when themechanism is fully optimized.

Awards and Honors:Academic Excellence, Mechanical Engineering

Tau Alpha Zeta

Pi Tau Sigma

Publications and Posters:Buckley, Jessica. An Investigation Into Straight-LineMechanisms: Optimizing the Peaucellier Mechanism; NationalConference on Undergraduate Research: Ithaca, NY, 2011.

JORDAN CARLSONUniversity of California, San DiegoSchool of Medicine

Degrees:M.A. in Health Psychology, San Diego StateUniversityB.A. in Psychology, University of Kansas

Scholar Sponsors:Timken-Sturgis Foundation

About the Scholar:Jordan’s research focuses on identifying and promotingenvironmental as well as policy approaches to improvingphysical activity and nutrition. By incorporating evidence-based public health into decision-making in schools,neighborhoods, and workplaces, people will face fewer barriersto being physically active and eating a healthier diet. This willresult in reduced risk for chronic conditions such as diabetes,cardiovascular diseases, and obesity.

Benefits to Society:Jordan's research will first help identify and understand bestapproaches to improving environments and policies related tophysical activity and nutrition in schools and in neighborhoods.Second, his research will involve working with decision makersto adopt and implement healthier practices. By incorporatingevidence-based public health into decision making aroundschools and neighborhoods, as well as other settings such asworkplaces, people will face fewer barriers to being physicallyactive and eating a healthy diet, and ultimately have less riskfor chronic diseases such as diabetes, cardiovascular disease,and obesity.

Awards and Honors:The California Endowment Research Grant

Publications and Posters:Carlson, J.A.; Sallis, J.F.; Chriqui, J.F.; Schneider, L.; McDermid,L.C.; Agron, P. State policies about physical activity minutes inphysical education or during the school day. Journal of SchoolHealth (in press).

Sallis, J.F.; Carlson, J.A.; Mignano, A. Promoting youth physicalactivity through PE and after-school programs. AdolescentMedicine: State of the Art Reviews (in press).

Carlson, J.A.; Sallis, J.F.; Conway, T.L.; Saelens, B.E.; Frank, L.D.;Kerr, J.; Cain, K.; King, A.C. Interactions between psychosocialand built environment factors in explaining older adults'physical activity. Preventive Medicine. 2012, 54(1), 68-73.

Sallis, J.F.; Millstein, R.A.; Carlson , J.A. Community design forphysical activity. In Dannenberg, A.; Frumkin, H.; Jackson, R.(Eds.). Making healthy places: designing and building forhealth, well-being, and sustainability. Washington DC: IslandPress 2011; 22-49.

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PHILLIP E. C. COMPEAUUniversity of California, San DiegoPhysical Sciences

Degrees:M.A. in Pure Mathematics, University ofCalifornia, San DiegoMaster of Advanced Study inMathematics, Cambridge UniversityB.S. in Mathematics, Davidson College

Scholar Sponsors:ARCS Foundation Endowment Fund

About the Scholar:Phillip is researching combinatorial models for genomerearrangements, which are rare large-scale mutations that drivespecies evolution. Phillip is also active in the bioinformaticseducation community and has recently co-founded Rosalind, awebsite that serves as a platform for beginners to learnbioinformatics through programming and problem solving.Phillip was once a professionally ranked tennis player and isnow an avid golfer.

Benefits to Society:The human genome was sequenced in 2001 at a cost of $3billion (and led to an economic boom whose value hassurpassed $500 billion). In the ten years since this monu-mental scientific event, several more mammalian genomeshave been sequenced at an exponentially decreasing cost. TheGenome 10K Project, founded in 2009, aims to sequence 10,000animal genomes to create a "zoo" of genomes. With eachgenome containing billions of nucleotides, the most advancedanalytic techniques are required to examine the data derivedfrom tens of trillions of nucleotides. Furthermore, a new brandof biologist is needed to handle the increasingly quantitativetasks arising from modern biology, calling for a revolution inthe traditional biology curriculum. Resources like Rosalind willhopefully help facilitate this revolution by providing freeeducation for students who have never had access to such aplatform, and it will serve as a resource for massively scalinguniversity biology education.

Awards and Honors:Thomas Smith ScholarshipPhi Beta Kappa

Publications and Posters:Compeau, P.E.C.; Pevzner, P.A.; Tesler, G. How to apply deBruijn graphs to genome assembly. Nature Biotechnology.2011, 29, 987-991.

Compeau, P.E.C.; Pevzner, P. Genome reconstruction: A puzzlewith a billion pieces. Chapter appearing in Bioinformatics forBiologists (textbook). Expected publication September 2011.

Compeau, P.E.C. Girth of pancake graphs. Discrete AppliedMathematics 2011, 159 (15), 1641-1645.

Heyer, L.J.; Poet, J.L.; Broderick, M.L.; Compeau, P.E.C.; Dickson,J.O.; Harden, W. L. Bacterial computing: Using E. coli to solvethe burnt pancake problem. Math Horizons 2010, 17(3), 5-10.

Compeau, P.E.C. A simplified view of DCJ-indel distance.Lecture Notes in Computer Science 2012, 7534, 365-377.

CASEY CONGERUniversity of California, San DiegoPhysical Sciences

Degrees:M.S. in Physics, University of California, San DiegoB.A. in Physics, Cornell University

Scholar Sponsors:Beyster Family Foundation Fund IV

About the Scholar:Casey is studying slight fluctuations and variations of radiationthroughout the Cosmic Microwave Background. These slightvariations are hypothesized to be the fluctuations of energyfields in the early universe. Since these variations took place onsuch a small scale, they need to be explained by quantum fieldtheory, physicists’ best theory to explain the behavior of matteron very small scales. Cosmology holds very deep questionsthat only recently have begun to be critically explored andtested. Casey admits that physics occupies most of his time,although he does enjoy reading.

Benefits to Society:Physics has done an extremely good job describing the worldas we see it now; Cosmology, however, attempts to explainhow the universe got to the state in which we currently see it.Until very recently, Cosmology has largely been metascience,overflowing with theories and no way to test them. Butphysicists are in the dawn of a precision age in Cosmology,where they now have accurate data to discriminate against andrule out different theories. Therefore, while Casey’s research willnot help us build a better iPod or let cars get 200 miles to thegallon, it is instead investigating a very deep question, whichdue to recent experiments, has only begun to be criticallyexplored and tested.

Awards and Honors:Fellowship for Excellence in Physics

The Benson Leister Scholarship

The National Science and Mathematics Access to Retain Talent Grant

John and Elizabeth Holmes Teas Scholarship

Lane Granville B. Memorial Scholarship

Robert W. and Ann M. Emery Endowed Scholarship

Donald L. and Ellen Eberly Endowed Scholarship in Science

Publications and Posters:Chen, K.; Cole, J.; Conger, C.; Draskovic, J.; Lohr, M.; Klein, K.;Scheidemantel, T.; Schiffer, P. Granular materials: packing grainsby thermal cycling. Nature 2006, 442.

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LAURA CONNELLYUniversity of California, San DiegoJacobs School of Engineering

Degrees:M.S. in Materials Science and Engineering,University of California, San DiegoB.S. in Materials Science and Engineering,Cornell University

Scholar Sponsors:Ellen Browning Scripps Foundation

About the Scholar:Laura is studying the structure of proteins associated withneurodegenerative diseases, specifically the amyloid betapeptide seen in Alzheimer’s disease. Through the use of atomicforce microscopy, she is identifying changes in the mechanicaland structural properties of specifically mutated forms ofamyloid beta. The findings from these studies may directlyinfluence the design and development of therapeuticinterventions to control or prevent amyloid beta-relateddiseases. In addition, she is implementing microscopy designimprovements to better observe the properties and behavior ofamyloid beta and other proteins of interest. Outside of the lab,Laura can be found running half-marathons or attending theconcerts of her favorite bands.

Benefits to Society:The benefits to society from Laura’s research are widespreadand significant. The information provided by her studies willdirectly aid the development of therapeutics for Alzheimer'sdisease. The aim of her research is to provide vital informationon the toxic mechanisms of Alzheimer's disease, therebyfacilitating the design and development of drugs to specificallytarget these mechanisms. Laura’s work will promote advance-ments in diagnosis and prevention and will provide a greaterunderstanding of disease symptoms. The findings of thesestudies may also have relevance to other neurological diseases,including Parkinson's disease and Huntington's disease.

Awards and Honors:National Defense Science and Engineering Graduate FellowshipNational Science Foundation Graduate Research FellowshipPowell FellowshipUCSD Gordon Scholar

Publications and Posters:Jang, H.; Connelly, L.; Teran Arce, F.; Ramachandran, S.; Kagan,B.; Lal, R.; Nussinov, R. Mechanisms for the insertion of toxic,fibril-like ‚-amyloid oligomers into the membrane. JACS,submitted July 2012.

Connelly, L.; Jang, H.; Teran Arce, F.; Ramachandran, S.; Kagan,B. L.; Nussinov, R.; Lal, R. Effects of point substitutions on thestructure of toxic Alzheimer’s ‚-amyloid channels: atomic forcemicroscopy and molecular dynamics simulations J. Biochem.2012, 51, 3031-3038.

Connelly, L.; Jang, H.; Teran Arce, F.; Capone, R.; Kotler, S.; Kagan,B.; Nussinov, R.; Lal, R. Atomic force microscopy and MDsimulations reveal pore-like structures of all-D-enantiomer ofAlzheimer’s-amyloid peptide: relevance to the ion channelmechanism of AD pathology J. Phys. Chem. B 2012, 11, 1728-1735.

MARTIS COWLESSan Diego State UniversityCollege of Sciences

Degrees:B.S in Biology, San Diego State University

Scholar Sponsors:Ellen Browning Scripps Foundation

About the Scholar:Martis is researching the regenerative capacity of the planarianSchmidtea mediterranea to model stem cell-based nervoussystem regeneration. Planarians are flatworms well known fortheir ability to regenerate all tissue types, including the nervoussystem, following amputation or injury. Martis is alsoinvestigating molecular mechanisms underlying planarian stemcell differentiation into various neuronal fates during tissuehomeostasis and regeneration. This study will provide insightsinto the basic mechanisms that underlie basic stem cell-basedtissue replacement and prove useful in treating neuro-degenerative diseases.

Benefits to Society:Neurogenesis was once believed to only occur duringdevelopment, but adult neurogenesis has now been observedin most animals (including humans). This new appreciationholds promise for the development of stem cell-basedtherapies to treat neurodegenerative diseases or spinal cordinjuries.

Awards and Honors:Best Student Poster Award, Society for Developmental Biology

Regional Meeting

President’s Award, San Diego State University Student Research Symposium

2nd Place, California Student Research Competition

Publications and Posters:Cowles, M.W.; Hubert, A.; Zayas, R.M. A Lissencephaly-1-likegene is required for mitotic progression in the planarianSchmidtea mediterranea. (In preparation).

Cowles, M.W.; Hubert, A.; Zayas, R.M. A Lissencephaly-1-likegene is required for stem cell maintenance in the planarianSchmidtea mediterranea, 70th Society for DevelopmentalBiology Annual Meeting, Chicago, IL.; July 21-25, 2011.

Cowles, M.W.; Hubert, A.; Zayas, R.M. A planarian ortholog ofLissencephaly-1 is required for stem cell maintenance. SanDiego State University Student Research Symposium, Abs.#466, San Diego, CA. March 4-5, 2011.

Cowles, M.W.; Zayas, R.M. Identification and functional analysisof neuronal migration genes in planarians. San Diego StateUniversity Student Research Symposium, Abs. #362, SanDiego, CA. March 5-6, 2010.

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CHRISTOPHER DEBOEVERUniversity of California, San DiegoBioinformatics and Systems Biology

Degrees:B.S. in Mathematical Biology, HarveyMudd College

Scholar Sponsors:The Heller Foundation of San Diego

About the Scholar:Chris uses next generation RNA-sequencing and high-throughput genomics to study cancer etiology and progression.He is searching for the changes that cause chronic lymphocyticleukemia (CLL) to transform from a dormant, less active cancer,to a more aggressive cancer that requires treatment. His hopeis to design a signature that predicts whether patients willrequire treatment soon after diagnosis. Understanding howCLL evolves to an aggressive disease may lead to newtherapeutic targets. When not on his computer, Chris enjoyscamping, sports, and playing guitar.

Benefits to Society:The sequencing revolution in biology has provided us with awell-documented flood of data. Processing, interpreting, andutilizing these data presents unique challenges but also offersthe ability to study biology at an unprecedented level ofbreadth and depth. Next generation sequencing technology isused to characterize and study cancer at a deeper level thanever before. Using sequencing, we can group patients fortreatment, identify potential drug targets, and definerelationships between specific cancer mutations and treatmentefficacy. As more data are collected and methods are refined,society will eventually move into an era of personalized cancerdiagnosis and treatment, where cancer profiling via sequencingand other genomic approaches will be the standard of care.

Awards and Honors:UCSD Genetics Training Program

California Institute for Regenerative Medicine (CIRM)Interdisciplinary Stem Cell Training Program

Sigma Xi

Publications and Posters:DeBoever, C; Reid, E.G.; Wang, X.; Dumaop, W.; Smith, E.N.;Carson, D.; Richman, D.; Masliah, E.; Frazer, K.A. Wholetranscriptome sequencing enables discovery and analysis ofviruses in archived primary central nervous systemlymphomas. (in preparation).

Nevarez, P.A.; DeBoever, C.M.; Freeland, B.J.; Quitt, M.A.; Bush,E.C. Context dependent substitution biases vary within thehuman genome. BMC Bioinformatics, 11(1), 462.

DeBoever, C.; De Roes, B. How to skew(er) a parametric curve.Mathematics Teacher, 102(3): 231-237.

RUSSELL DEKELVERUniversity of California, San DiegoDivision of Biological Sciences

Degrees:B.A. in Molecular and Cell Biology,University of California, Berkeley

Scholar Sponsors:The Collins Companies, Ty & Diane Miller

About the Scholar:Russ is researching how specific genetic events contribute toacute myeloid leukemia (AML). Chromosomal translocations arecommon in AML, and the resulting fusion proteins alter cellulargene expression and signal pathways to promote leukemiadevelopment. Using both cellular and in vivo mouse models, hecan determine which pathways are critical for leukemiadevelopment so that targeted therapies can be developed thatare more effective and have fewer side effects than radiation andchemotherapy. When out of the lab, Russ enjoys backpacking,running and playing basketball with his classmates.

Benefits to Society:AML is the most common form of leukemia in adults, and it isestimated that nearly 14,000 new cases will be diagnosed thisyear in the United States alone. Though survival rates varydepending on age and a number of other factors, on averagethere is a 25-50% chance of surviving 5 years after diagnosis.The majority of patients are treated with radiation andchemotherapy, which have some very harmful side effects, orthrough stem cell transplantation, for which it is often difficultto find an appropriate donor.The goal of this research is toidentify new drug targets and develop new methods oftreatment for this disease. Russ hopes that this will increaseboth the quality of life of patients during their treatment andtheir chance of survival afterwards.

Awards and Honors:NIH Cellular and Molecular Genetics Training Grant Recipient

AAAS/Science Program for Excellence in Science

Publications and Posters:Ahn, E.Y.; Higashi, T.; Yan, M.; Matsuura, S.; Lo, M.C.; Shia, W.J.;DeKelver, R.C.; Zhang, D.E. SON regulates GATA-2 throughtranscriptional control of the miR-23a~27a~24-2 cluster (inpreparation).

Ahn, E.Y.; DeKelver, R.C.; Lo, M.C.; Nguyen, T.A.; Matsuura, S.;Boyapati, A.; Pandit, S.; Fu, X.D.; Zhang, D.E. SON controls cellcycle progression by coordinated regulation of RNA splicing.Molecular Cell 2011, 42, 185-98.

DeKelver, R.C.; et al. Functional genomics, proteomics, andregulatory DNA analysis in isogenic settings using zinc fingernuclease-driven transgenesis into a safe harbor locus in thehuman genome. Genome Res. 2010, 20, 1133-42.

DeKelver, R.; Yan, M.; Ahn, E.Y.; Speck, N.A.; Zhang, D.E.Relative importance of NCoR and SON interactions with NHR4domain of AML1-ETO in leukemogenesis. 17th InternationalRUNX Workshop. Hiroshima, Japan, 2010.

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KATHARINE DUNCANThe Scripps Research Institute Kellogg School of Science and Technology

Degrees:B.A. in Chemistry, Amherst College

Scholar Sponsors:Reuben H. Fleet Foundation Fund

About the Scholar:The active ingredient of marijuana, tetrahydrocannabinol, THC,mimics the action of naturally occurring molecules of the bodyin response to pain stimulus. This research aims to find a wayto exploit the endocannabinoid system to produce effective,long-lasting relief from pain without the adverse andpsychotropic side effects. The regulation of endocannabinoidshas the potential for management of pain, anxiety, sleepdisorders, epilepsy, stroke, and chronic inflammatory disorders.Katherine enjoys outside activities and is a member of akickball team.

Benefits to Society:The origin of marijuana’s potency as a homeopathic, and highlycontroversial, medicine is that the active ingredient delta- 9-tetrahydrocannabinol (THC) mimics the action of similarnaturally occurring molecules (endocannabinoids) produced bythe body in response to pain stimulus. But in addition todecreasing sensitivity to pain, THC causes a number of otherside effects as it activates signaling pathways in other parts ofthe body and brain, including cognitive and motor dysfunction,anxiety, and increased heart rate and blood pressure. The aimof Katharine’s research is to find a way to exploit theendocannabinoid system to produce effective, long-lastingrelief from pain without the adverse and psychotropic sideeffects. The goal is to modulate the concentrations of theseendocannabinoids, thus increasing their effects in a variety ofphysiological processes including mood, memory, appetite, andpain sensation.

Awards and Honors:Forris Jewett Moore Fellowship

Gustavus and Louise Pfeiffer Research Foundation Graduate Student Fellowship

The Scripps Research Institute Dean’s Fellowship

American Institute of Chemists Prize

Publications and Posters:Wolfe, A. L.; Duncan, K. K.; Parelkar, N. K.; Weir, S. J.; Vielhauer,G. A.; Boger, D. L. A novel, unusually efficacious duocarmycincarbamate prodrug that releases no residual byproduct. J. Med.Chem. 2012, 55 (12), 5878.

Leggans, E. K.; Barker, T. J.; Duncan, K. K.; Boger, D. L.Iron(III)/NaBH4-mediated additions to unactivated alkenes:synthesis of novel 20’-vinblastine analogues. Org. Lett. 2012, 14(6), 1428.

Gotoh, H.; Duncan, K. K.; Robertson, W. M.; Boger, D. L. 10’-fluoro-vinblastine and 10’-fluorovincristine: synthesis of a key series ofmodified vinca alkaloids. Med. Chem. Lett. 2011, 2(12), 948.

JENNIFER EMONDUniversity of California, San Diego Graduate School of Public HealthDegrees:M.S. in Statistics, University ofMassachusetts, Lowell, MAB.A. in Epidemiology, University of Massachusetts, Amherst, MA

Scholar Sponsors:Hervey Family Non-endowment Fund

About the Scholar:Jennifer is concentrating on encouraging dietary and physicalactivity changes among breast cancer survivors. She examineswhich carbohydrate subtypes relate to breast cancer recurrenceand how changes in hormones like estrogen, testosterone,insulin, and insulin-like growth factor (IGF), in relation to carbo-hydrate intake, impact tumor tissue growth. She presentlyleads an immunohistochemical analysis to determine howexpression of the IGF-1 receptor in primary breast tumor tissuemediates the relationship between carbohydrate intake andbreast cancer recurrence. Jennifer’s free time is spent with herhusband and daughter.

Benefits to Society:Many breast cancer survivors are motivated to make positivelifestyle changes after their diagnosis. Survivors are motivated tobetter understand how diet may influence breast tumor growth,and many survivors make dietary changes in an attempt toimprove prognosis. However, there are many mixed messagesregarding how specific foods may impact prognosis, andsurvivors are often confused as to which advice to follow. Onepopular area of study is carbohydrate intake and breast cancergrowth. There are several subtypes of carbohydrates and variousfood groups that contribute carbohydrates to the diet. These foodgroups also have varying levels of other macronutrients such asfat and protein. Therefore, it is important to differentiate foodgroups based on the carbohydrate content of specific subtypesinstead of simply identifying total carbohydrate content. Byunderstanding how the intake of specific carbohydrate subtypesmay impact prognosis and through which biological mechanismsthis may occur, we are better informed to provide breast cancersurvivors with appropriate advice about dietary changes after abreast cancer diagnosis.

Awards and Honors:Ruth L. Kirschstein National Research Service Award pre-

doctoral fellowUCSD Transdisciplinary Research in Energetics and Cancer

(TREC) Scholar

Publications and Posters:Emond, J.A.; Patterson, R.E.; Natarajan, L.; Laughlin, G.A.; Gold,E.B.; Pierce, J.P. Sex hormone concentrations and the risk ofbreast cancer recurrence in postmenopausal women withouthot flashes. Cancer Epidem Biomar. 2011, 20, 939-945.

Emond, J.A.; Madanat, H.N.; Ayala, G.X. Do Latino and non-Latino grocery stores differ in availability and affordability ofhealthy food items in a low income, metropolitan region?Public Health Nutr. 2011, 7, 1-10.

Caan, B.C.; Emond, J.A.; Su, I.; Patterson, R.E.; Flatt, S.W.; Gold,E.B.; Newman, V.A.; Rock, C.L.; Thomson, C.; Pierce, J.P. Theeffect of post-diagnosis weight change on hot flash statusamong early stage breast cancer survivors. J Clin Oncol. 2012,30, 1492-1497.

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KATHLEEN FITZPATRICKUniversity of California, San DiegoSchool of Medicine

Degrees:B.S. in Biochemistry, Molecular Biology, Biology, and History, University of Wisconsin, Madison

Scholar Sponsors:Kenneth & Marjorie Blanchard

About the Scholar:Kathleen is studying HIV and how the immune system reacts toinfection. Her work specifically focuses on understanding thecomponent that can prevent the spread of infection bytethering viruses to the surface of infected cells. HIV contains afactor that disrupts the tethering activity, allowing release andspread of infection. By understanding how the body naturallytries to contain infection, we will understand the potentialpoints of weakness in the viral replication cycle. Kathleen is anavid road cyclist.

Benefits to Society:By understanding more about the way the body naturally triesto contain an infection, scientists understand more aboutpotential points of weakness in the viral replication cycle.Researchers can potentially use this information to designtherapeutics to enhance this interaction. Additionally, it isimportant to understand the context of this molecular tether inan uninfected individual and its global use in the immunesystem so potential side effects of drugs designed to modifythis protein are fully understood.

Awards and Honors:California HIV/AIDS Research Dissertation Scholar

Conference on Retroviruses and Opportunistic Infections Young Investigator

Publications and Posters:Fitzpatrick, K.; Skasko, M.A.; Deerink, T.J.; Crum, J.; Ellisman,M.H.; Guatelli, J.C. Direct restriction of virus release byincorporation of the Interferon-induced protein BST-2 into HIV-1particles. PLoS Pathog. 2010, 6(3), e1000701.

Tokarev, A.; Skasko, M.; Fitzpatrick, K.; Guatelli, J. Antiviralactivity of the Interferon-Induced cellular protein BST-2/Tetherin. AIDS Research and Human Retroviruses 2009,25(12).

Mitchell, R.S.; Katsura, C.; Skasko, M.A.; Fitzpatrick, K.; Lau, D.;Ruiz, A.; Stephens, E.B.; Margottin-Goguet, F.; Benarous, R.;Guatelli, J.C. Vpu antagonizes BST-2-mediated restriction of HIV-1 release via beta-TrCP and endolysosomal trafficking. PLoSPathog. 2009, 5(5).

Schmitz, R.J.; Hong, L.; Fitzpatrick, K.E.; Amasino, R.M.; DICER-LIKE 1 and DICER-LIKE 3 redundantly act to promote floweringvia repression of FLOWERING LOCUS C in Arabidopsis thaliana.Genetics 2007, 176(2), 1359-62.

LAURIE GAYThe Scripps Research InstituteKellogg School of Science and Technology

Degrees:B.S. in Biology, California PolytechnicState University, San Luis Obispo

Scholar Sponsors:Webster & Helen Kinnaird, Paul Bechtner Foundation

About the Scholar:Laurie is investigating the interaction of cancer cells with thehost environment, including the blood vessels and blood cellswhich may protect the metastatic cells, preventing them fromleaving the blood stream. Blood platelets have long beenknown to play a supportive role in cancer and metastasis, yetthe precise mechanisms that platelets contribute to tumorgrowth and the metastatic process remain elusive. She ishighly motivated to perform experiments that can advancepreventative treatment and effective therapies. Laurie enjoysreading modern literature, tennis and running in the TorreyPines State Park.

Benefits to Society:The primary goal of this project is to identify key host cells andtheir functions that contribute to the survival of breast cancercells within the circulatory system and during exit from theblood stream and metastatic growth. There is both anopportunity and a critical need for breakthrough research inthis field since 90% of cancer-related deaths are due tometastasis. Laurie is strongly motivated to perform the plannedexperiments in hopes of advancing preventative treatment andeffective therapies. She is convinced that results from her studywill advance the cancer field significantly, contributing to animprovement of human health in situations where otherwisethere are few treatment options available. If successful, resultsfrom her studies will provide mechanistic insight into theprocess of metastasis and could lay a foundation for new andeffective therapies to prevent and treat metastatic disease.

Awards and Honors:NIH Clinical and Translational Science Awards Traineeship

Network for Women in Science, Public Relations Officer

Publications and Posters:Gay, L.J.; Felding-Habermann, B. Contribution of platelets totumour metastasis. Nature Reviews Cancer 2011, 11, 2, 123-34.

Pertz, O.C.; Wang, Y.; Yang, F.; Wang, W.; Gay, L.J.; Gristenko,M.A.; Clauss, T.R.; Anderson, D.J.; Liu, T.; Auberry, K.J.; Camp,D.G.; Smith, R.D.; Klemke, R.L. Spatial mapping of the neuriteand soma proteomes reveals a functional Cdc42/Rac regulatorynetwork, Proceedings of the National Academy of Sciences ofthe United States of America, 2008;105,6, 1931-1936.

Gay, L.J.; Goeske, G.; Black, M.; Adams, N. Sequencing andexpression of checkpoint Kinase 1 in Strongylocentrotuspurpuratus, American Society for Cell Biology, San Francisco,CA., 2006 22.

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WESLEY GIFFORDUniversity of California, San DiegoSchool of Medicine

Degrees:B.S. in Neuroscience, University ofCalifornia, Los Angeles

Scholar Sponsors:Larry & Mara Ybarrondo, ARCS Foundation

About the Scholar:Wes is working on problems associated with amyotrophiclateral sclerosis (ALS). He is developing new animal and invitro stem cell models to study mechanisms of disease that canalso be used to test novel drug therapies. He is involved with amulti-lab and biotech collaboration aimed at creating a stemcell-based transplant therapy for ALS. Simultaneously, he isresearching how the many different cell types in the nervoussystem are generated by using genome sequencing techno-logies that are destined to become a mainstay in future clinicalmedicine. When not working, Wesley enjoys spending time inthe mountains.

Benefits to Society:Research on ALS over the past two decades has focused on arare subtype of disease. In contrast, Wesley’s research takesadvantage of a recent discovery that links a newly identifiedgene to the vast majority of cases. By establishing new diseasemodels based on mutations in this new gene, the scientificcommunity will be able to study more relevant features of thedisease and hopefully develop new therapies. In addition, themethods employed and optimized by Wesley for a collaborativeproject designed to generate a cell transplant therapy for ALSwill have an impact on how human cell transplants aremonitored, regardless of the particular disease being studied.Moreover, his work to study cell type diversity in the nervoussystem will improve our understanding of the different celltypes in the spinal cord that are responsible for coordinatedbody movement.

Awards and Honors:Rose Hills Foundation Graduate Fellowship

H.A. and Mary K. Chapman Charitable Trust Scholar

California Institute for Regenerative Medicine GraduateFellowship

Phi Beta Kappa

Publications and Posters:Gifford, W.D.; Hayashi, M.; Sternfeld, M.; Tsai, J.; Alaynick, W.A.;Pfaff, S.L.. Spinal Cord Patterning. (Book chapter inComprehensive Developmental Neuroscience, in press).

Macfarlan, T.S.; Gifford, W.D.; Driscoll, S.; Lettieri, K.; Rowe,H.M.; Bonanomi, D.; Firth, A.; Singer, O.; Trono, D.; Pfaff, S.L.Embryonic stem cell potency fluctuates with endogenousretrovirus activity. Nature. 2012, Jul 5;487(7405):57-63.

Bruno, I.; Karam, R.; Huang, L.; Bhardwaj, A.; Lou, C.H.; Shum,E.Y.; Gifford, W.D., Pfaff, S.L.; Wilkinson, M.F. Identification of amicroRNA that activates gene expression by repressingnonsense-mediated RNA decay. Mol Cell. 2011, May20;42(4):500-10.

CHARLES GRANGERSan Diego State UniversityCollege of Sciences

Degrees:B.S. in Physics, Sonoma State University

Scholar Sponsors:Cymer, Inc.

About the Scholar:Charles is studying diffractive optical elements used in a largevariety of laser-based systems due to their ability to split,pattern, and shape beams, and their capability for wave frontcorrection and their creation of optical vortices. Polarizationcontrol is increasingly important in fiber-optic communications,remote sensing and lithography. His aim is to improve theability to independently control the polarization of multiplebeams generated from one source. In his free time, Charlesenjoys surfing, bouldering, and backpacking.

Benefits to Society:The research Charles is doing involves passing a laser beamthrough a programmable liquid crystal display and using thedisplay to manipulate characteristics of the laser beam,including its direction and intensity. He uses a liquid crystaldisplay where each pixel is individually programmed to make apattern on the screen. The laser light passing through ismanipulated depending on the pattern on the display. Thebeam can be split into a number of beams, redirected, focusedas if passing through a lens, or have any number of morecomplex tricks applied. His research will focus on enhancingthe control of these beams by finding a way to individuallycontrol the polarization, which is becoming increasinglyimportant in a number of applications for lasers.

Awards and Honors:Wilmia Tyler Trott Memorial Scholarship

Albuquerque AFRL Directed Energy Scholars SummerInternship

Publications and Posters:Davis, J.A.; Albero, J.; Moreno, I.; Cottrell, D.M.; Granger, C.E.;McCormick, K. Asymmetric grating beam splitters with phasecontrol. (in preparation)

Granger, C.E. Measuring the anti-guiding parameter inquantum well mid-infrared optically pumped semiconductorlasers. Directed Energy Test and Evaluation Conference,Sheraton Uptown, Albuquerque, NM, Aug 7, 2012.

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MICHAEL GURNEY, JR.San Diego State UniversityCollege of SciencesDegrees:M.S. in Cell and Molecular Biology, SanDiego State UniversityB.S. Biochemistry and Cell Biology, University of California, San DiegoA.A. University Studies, Grossmont College

Scholar Sponsors:ARCS Foundation, Betty Jo Williams

About the Scholar:Michael is researching how lowering caloric intake has thepotential to decrease inflammation, improve aspects ofimmune function, and decrease the amount of dead tissuefollowing heart attack. If inflammation is left unchecked, it hasa profound impact on how our bodies repair themselves andhow long we live, how our bodies repair themselves followinginjury and how we handle infectious disease. Michael spendshis spare time biking, walking and reading.

Benefits to Society:For his doctoral thesis, Michael is examining the interactionbetween inflammation, autophagy, and aging. Autophagy andinflammation work against each other to promote cellularfunction, survival, and tissue repair following an acute stress,such as heart attack or infection. As organisms age, theseprocesses become dysregulated and the likelihood ofsuccessful tissue repair or survival following injury declines,implying that tweaking the autophagy and inflammationpathways could improve survival and tissue repair. Michaelrecently demonstrated that autophagy declines while othershave shown increased inflammation with age. Periodic fastingis thought to increase autophagy (and probably decreaseinflammation). Upon intermittently fasting middle-aged miceuntil they were elderly, Michael found partial restoration ofsome immune cell function and a decline in the tissue damagedone by heart attack in old mice, making fasting a possibletherapy to improve heart attack survival, mitigate age-relatedinflammatory diseases, or perhaps increase vaccine efficacy inthe elderly.

Awards and Honors:Grossmont President Honors

UCSD President Honor

Navy Achievement Medal

Navy Good Conduct Medal

Phi Beta Kappa

Publications and Posters:Gurney, M.A.; Linton, P.J. Autophagy and Immunology. 2012.(Book chapter in Autophagy in Health and Disease)(in press).

Burnside, K.; Lembo, A.; Harell, M.; Gurney, M.A.; Xue, L.; Binh,T.; Connelly, J.; Jewel, K.; Schmidt, B.; de los Reyes, M.; Tao, W.;Doran, K.S.; Rajagopal, L. The serine/threonine phosphataseStp1 is important for post-transcriptional regulation ofhemolysin and virulence of Group B Streptococci. J. Biol.Chem. 2011, 286(51), 44197-44210.

ERILYNN HEINRICHSENUniversity of California, San DiegoSchool of Medicine

Degrees:B.A. in Biology, Luther College

Scholar Sponsors:The Samuel I. & John Henry Fox Foundation, ARCS Foundation

About the Scholar:Erilynn is researching the genetics of obesity and hypoxia (lowoxygen), using Drosophila melanogaster (fruit flies) as a model.She has characterized the phonotypic changes that occur whenflies are exposed to a high-fat diet and hypoxia, both aschallenges and interacting factors. Using this model, shehopes to uncover the genetic mechanisms underlying thealtered phenotype due to obesity and hypoxia. This knowledgeof the genetic response to a high-fat diet, with or withouthypoxia, can be translated into vertebrate models and impactour treatment and understanding of the associated humanconditions. Erilynn enjoys cycling, hiking and ocean kayaking.

Benefits to Society:Over 60% of the population in the United States is estimated tobe obese or overweight, and with obesity comes many diseasecomplications, including sleep apnea, atherosclerosis,cardiovascular diseases and stroke. Several of thesecomplications also involve hypoxia, yet the fundamental basicmechanisms underlying the interaction of obesity and hypoxiaremain unknown. Drosophila, as a model organism, offerstremendous power in uncovering and studying fundamentalmechanisms, given the abundance of molecular tools availableto delve into the roles of specific genes and the conservation ofbiochemical pathways. In this research, Erilynn has shown thatthe detrimental effects of a high-fat diet are clear in a Drosophilamodel, and there appears to be both deleterious andcompensatory cross talk occurring between hypoxia and thehigh-fat diet. With the climbing global obesity levels and lack ofunderstanding of the interaction between obesity and hypoxia,developing an animal model that lends itself to an investigationof this interaction is vital, as it allows us to deepen ourknowledge of what genes and pathways play a role in theresponse to these conditions.

Awards and Honors:National Science Foundation GK-12 Socrates FellowAssociation of Women in Science Scholarship RecipientUCSD Genetics Training Grant RecipientWigeland Scholarship for study in ScandinaviaPhi Beta Kappa

Publications and Posters:Heinrichsen, E.T.; Haddad, G.G. Role of high-fat diet in stresstolerance of Drosophila. PLoS One. 2012, 7(8), e42587.

Azad, P.; Zhou, D.; Russo, E.; Haddad, G.G. Distinct mechanismsunderlying tolerance to intermittent and constant hypoxia inDrosophila melanogaster. PLoS One. 2009, 4(4), e5371.

Riley, B.M.; Mansilla, M.A.; Maher, B.S.; Russo, E.T.; Vieira, A.R.;Daack-Hirsch; S.; Marazita, M.L.; Murray, J.C. Mutations ingenes in FGF signaling pathway contribute to cleft lip andpalate. Proc Natl Acad Sci. 2007, 104, 4512–4517.

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MARCEL HETUSan Diego State UniversityCollege of Sciences

Degrees:M.S. in Chemistry, San Diego StateUniversityB.S. in Chemistry, San Diego State University

Scholar Sponsors:ARCS Foundation, Betty Peabody

About the Scholar:Marcel is using lasers to detect proteins associated withneurodegenerative and autoimmune diseases. The highselectivity and sensitivity of the lasers make it possible toidentify biomarkers in the early stages of disease. Theprocedure uses extremely small sample sizes, such as a singlecell, and utilizes a multi-photon non-linear laser wave mixingtechnique. He has studied biomarkers associated with cancer,HIV and Alzheimer’s disease. Marcel has also used lasers todetect explosives. This technology has the potential to savelives by reporting the presence of explosives from longdistances. Marcel has varied interests, among them hiking thetrails throughout San Diego County.

Benefits to Society:This work could make significant contributions to society.Current diagnostic measurements for disease require multiplevials of blood to be collected and often involve costly and time-consuming work-up for more advanced measurements such asviral loads. This technique requires only a single cell to makemeasurements of the cell’s protein content. The sensitivity ofthe technique allows for the development of early detectiondiagnostic methods. High sensitivity, selectivity, and smallsample size requirements makes the technique ground-breaking for the way diseases could be discovered and treated.

Awards and Honors:Sigma Xi

Publications and Posters:Hetu, M. H. Synthesis and reactivity of new transition metalcomplexes for environmentally and biologically relevantchemistry. M.S. Thesis, San Diego State University, San Diego,CA, 2009.

Liang, H.; Zhang, Y.; Hetu, M. Phosphate diester hydrolysispromoted by new Cu(II) alkoxide complexes. InorganicChemistry Communications 2007, 10, 204-208.

Zhang, Y.; Liang, H.; Zakharov, L. N.; Das, S. K.; Hetu, M.Carboxyester hydrolysis promoted by Cu(II) complexes ofpyridyl-amine carboxylate-pendant ligands. Inorganica ChimicaActa 2007, 360, 1691-1701.

STEPHANIE HUELGAUniversity of California, San DiegoBioinformatics and Systems Biology

Degrees:B.S. in Bioinformatics, University ofCalifornia, Santa Cruz

Scholar Sponsors:ARCS Foundation, Susan Hoekenga &Edward Gergosian

About the Scholar:Stephanie analyzes thousands of gigabytes of sequencing datato understand how RNA binding proteins affect RNAprocessing events. She is especially interested in identifyingthe cause of RNA processing defects that occur in many humandiseases in hopes of aiding in drug design. While Stephaniespends most of her time performing bioinformatic analyses,she also does bench experiments generating data andvalidating her findings. Stephanie is an avid rock climber andenjoys hiking and yoga.

Benefits to Society:Many human diseases result from the mis-regulation of RNAprocessing, such as Spinal Muscular Atrophy, and AmyotrophicLateral Sclerosis. By understanding how RNA binding proteinsaffect the processing of RNA in these diseases, we can help toefficiently target drug design to these proteins to repair themis-regulation, and potentially reverse the effects of thesediseases. The success of this research has the added bonus ofhelping deconvolute the complexities of RNA processing byRNA binding proteins, a field of great scientific interest to manyresearch groups.

Awards and Honors:National Science Foundation Graduate Research Fellowship

National Institute of General Medical Sciences Ancillary TrainingProgram Travel Scholarship

Cancer Cell Biology Training Grant, UC San Diego

National Science Foundation AGEP Fellowship, UC San Diego

Publications and Posters:Wilbert, M.W.; Huelga, S.C.; Kapeli, K.; Stark, T.J.; Liang, T.Y.;Chen, S.X.; Yan, B.Y.; Nathanson, J.L.; Hutt, K.R.; Lovci, M.T.;Kazan, H.; Vu, A.Q.; Massirer, K.B.; Morris, Q.; Hoon, S.; Yeo, G.W.LIN28 binds messenger RNAs at GGAGA motifs and regulatessplicing factor abundance. Molecular Cell, 2012. (in press)

Huelga, S.C.; Yeo, G.W. Alternative Splicing in Stem Cells. InComputational Biology of Embryonic Stem Cells; Zhan, M., Ed.;Bentham Science Publishers, 2012. p 147-160.

Huelga, S.C.; Vu, A.Q.; Arnold, J.D.; Liang, T.Y.; Liu, P.P.; Yan, B.Y.;Donohue, J.P.; Shiue, L.; Hoon, S.; Brenner, S.; Ares, M.; Yeo,G.W. Integrative genome-wide analysis reveals cooperativeregulation of alternative splicing by hnRNP proteins. CellReports, 2012.

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MANNA IWABUCHISan Diego State UniversityCollege of Sciences

Degrees:B.A. in Liberal Arts, International ChristianUniversity

Scholar Sponsors:Samuel H. French III & Katherine Weaver French Fund

About the Scholar:Manna’s project involves the study of alpha synuclein, a proteinrelated to Parkinson’s disease. The plan is to develop ultra-sensitive laser-based detection methods for these importantproteins. So far these studies indicate that alpha synuclein andserotonin can be detected by this method with better chemicalselectivity levels, enhanced detection sensitivity levels andhigher spectral and spatial resolution levels as compared tocurrently available methods. These new tools for early detectionwould scientifically help Parkinson’s patients over the world.Manna enjoys cooking, swimming and working out in the gym.

Benefits to Society:Manna is especially interested in the early detection of proteinsrelated to Parkinson’s disease. Since Manna’s great grandfatherand grandparents suffered from Parkinson’s, she has first-handknowledge of the challenges associated with the disease.Currently, there is no specific cure, although some medicaltreatments are available that could slow the progressive courseof the disease. In her grandmother’s case, it took too manyyears to diagnose Parkinson’s disease, causing her to miss theideal time window for brain surgery. Manna is very motivatedto study and develop new ultrasensitive nonlinear laser-basedmethods to detect Parkinson’s disease at much earlier stagesbefore the symptoms appear. These new tools for earlydetection could significantly help Parkinson’s patients all overthe world.

Awards and Honors:Harry E. Hamber Memorial Scholarship

Wilmia Tyler Trott Memorial Scholarship

International Christian University Dean's List

Publications and Posters:Jimenez, J.; Gregerson, M.; Neary, T.; Hetu, M.; Iwabuchi, M.;Tong, W. Multi-photon nonlinear laser wave-mixing detection ofchemical and biological agents. SACNAS National Conference,San Jose, CA., Oct 27-30, 2011.

Iwabuchi, M.; Hetu, M.; Neary, T.; Tong, W. Sensitive analysis ofalpha synuclein by laser wave-mixing detection and capillaryelectrophoresis. CSUPERB Annual Symposium, Santa Clara,CA., January 7, 2012.

Iwabuchi, M.; Neary,T.; Hetu, M.; Wu, H.; Warren, A.; Tong, W.Ultrasensitive analysis of biomarkers by nonlinear laser wave-mixing detection and capillary electrophoresis. American Chem-ical Society National Meeting, San Diego, CA, March 25, 2012.

SARAH LEBOEUFThe Scripps Research InstituteKellogg School of Science and Technology

Degrees:B.S. in Biology, University of Texas atAustin

Scholar Sponsors:Union Bank

About the Scholar:Sarah’s research focuses on understanding what changes intumor metabolism to promote a malignant phenotype in breastcancer. Her goal is to understand how the class of NAD+dependent protein deacetylases, called sirtuins, function ascellular sensors of metabolism, and how changes in theiractivity may promote breast cancer progression. She is alsoexploring ways to ‘normalize’ tumor metabolism as a possibletherapeutic approach.

Benefits to Society:Sarah is studying how changes to tumor cell metabolismcontribute to breast cancer progression. During transformation,cells undergo several metabolic changes that may contribute todisease progression. Understanding changes that promote amalignant phenotype will give scientists and doctors a betterunderstanding of breast cancer progression and metastasis.Sarah is studying specifically how a group of proteins calledsirtuins, which modify the function and activity of a widevariety of other cellular proteins, regulate tumor metabolism.

Awards and Honors:NIH Clinical and Translational Science Awards Traineeship

The Scripps Research Institute Dean's Fellow

Signature Science Excellence in Chemistry Research Award

Publications and Posters:Santidrian, A.F.; Yagi, A.M.; Ritland, M.; Seo, B.B.; LeBoeuf, S.E.;Yagi, T. Felding-Habermann, B.; Enhancement of theNAD+/NADH redox balance by mitochondrial complex 1 activityand NAD+ precursor treatment inhibit breast cancerprogression and metastasis. (submitted)

Chung, M.I.; Peyrot, S.M.; LeBoeuf, S.E.; Park, T.J.; Marcotte,E.M.; Wallingford, J.B. RFX2 is broadly required for ciliogenesisduring vertebrate development. Developmental Biol. 2012, 1,155-165.

Umail, A.P.; LeBoeuf, S.E.; Newberry, R.W.; Kim, S.; Tran, L.;Rome, W.A.; Tian, T.; Taing, D.; Hong, M.; Kwan, Heymann, H.;Anslyn, E.V. Discrimination of flavonoids and red wine varietalsby arrays of differential peptidic sensors. Chemical Sci. 2010, 2,439-445.

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KATHERINE LEVANUniversity of California, San DiegoDivision of Biological Sciences

Degrees:B.S. in Biology, Tufts UniversityB.A. in Spanish, Tufts University

Scholar Sponsors:The Thomas C. Ackerman Foundation

About the Scholar:Katie is studying the ecological consequences of invasion bythe Argentine ant. Her work with this introduced species willclarify the side effects of exotic species on pollination of plantsand on food webs. A better understanding of the competitionbetween introduced ants and the native species will result inthe implementation of removal campaigns that minimizedamage to ecosystems and decrease the need for pesticides.When Katie is not working in the field, she is an avid hiker andenjoys backpacking and camping in the outdoors.

Benefits to Society:Katie’s research on an important invasive species will helpscientists better understand the consequences of anintroduction for biodiversity and ecosystem services(particularly biocontrol and pollination). Some of her datasuggest that aphids can distract the Argentine ant fromforaging in flowers, increasing pollination services for plantsthat host aphids. This led to increased seed production inplants. If follow-up experiments support this assessment, thenfarmers growing pollen-limited (pollinator-dependent) cropsmay be able to increase their yield and decrease pesticide usein areas with Argentine ants and aphids. Better management ofinvasive species starts with research that informs scientist ofthe role they fill in their new habitat. From this starting point,we can implement more effective removal campaigns thatminimize damage to native ecosystems.

Awards and Honors:NSF Graduate Research Fellow

Mildred Mathias Awardee

Jeanne M Messier Research Fellow

Highest thesis honors, Tufts University

Publications and Posters:LeVan, K.E.; Hung, K.J.; McCann, K.R.; Ludka, J.; Holway, D.A.Floral visitation by the Argentine ant reduces pollinatorvisitation and seed set in the coast barrel cactus, Ferocactusviridescens. (submitted)

Wilson, E.E.; Sidhu, C.S.; LeVan, K.E.; Holway, D.A. Pollenforaging behaviour of solitary Hawaiian bees revealed throughmolecular pollen analysis. Mol Ecol. 2010, 19(21): 4823-4829.

LeVan, K.E.; Fedina, T.Y.; Lewis, S.M. Testing multiplehypotheses for the maintenance of homosexual copulatorybehavior in flour beetles. J Evol Biol. 2009, 22: 60-70.

South, A.; LeVan, K.; Leombruni, L.; Orians, C.M.; Lewis, S.M.Examining the role of cuticular hydrocarbons in firefly speciesrecognition. Ethol. 2008, 114 (9): 916-924.

ELIZABETH LIGHTUniversity of San DiegoHahn School of Nursing and Health Science

Degrees:M.S. in Nursing Science, University of San DiegoB.S. in Nursing Science, Syracuse University

Scholar Sponsors:The Beyster Family Foundation Fund IV

About the Scholar:Elizabeth’s goal is to identify strategies that will reduce thelong-term adverse consequences of poor maternal andreproductive health in minorities and underserved populations.Her research aims to increase women’s awareness of theimportance of positive health practices before, during, and afterpregnancy to improve maternal-child health outcomes. Sheaims to maximize access, reduce treatment barriers, andimprove public health impact. Elizabeth enjoys spending timewith her husband and her daughter.

Benefits to Society:Diversity remains a significant challenge in healthcare withresearch on women’s health in pregnancy and the postpartumperiod, and disparities are a public health priority globally.Elizabeth’s research will examine the factors surroundingmaternal-fetal attachment and maternal health practices.Maternal-fetal attachment describes the relationship between apregnant woman and her fetus. There is limited researchexamining this relationship in general and, more specifically,among diverse populations of women. Examining maternal-fetal attachment can elucidate this dynamic and complex bond.Identifying the various elements of maternal behaviors andhow they inform women’s choices can provide insight intowomen’s health issues in order to improve maternal-childhealth outcomes.

Awards and Honors:Dean’s Merit Scholar

Blystone Family Scholarship

Sigma Theta Tau International Honor Society for Nursing

Nurse of Excellence Award, Neonatal Intensive Care Unit, RadyChildren’s Hospital San Diego

Publications and Posters:Light, E. Viewing Women’s Health from an Alternative Lens.Neonatal Network: The Journal of Neonatal Nursing. (In Press)

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CONNOR LINDUniversity of San DiegoSchool of Arts and Sciences

Scholar Sponsors:WD-40 Company

About the Scholar:Connor is designing solutions for energy poverty, sanitation,and water security to improve the quality of life in ruralcommunities around the world. He is using basic engineeringprinciples to understand the local culture that will eventuallylead to improvements in these critical features for thepreservation of health and life.

Benefits to Society:Connor’s research interests include the applications of

engineering to the developing world.

Awards and Honors:USD Alcala Merit Scholarship

USD Outstanding Engineering Sophomore Award

USD Academic Achievement Award

CATHERINA ANNE MADANIUniversity of San DiegoHahn School of Nursing and Health Science

Degrees:M.S. in Nursing Science, University of San DiegoB.S. in Nursing Science, University of Massachusetts, Amherst

Scholar Sponsors:Reuben H. Fleet Foundation Fund, ARCS Foundation

About the Scholar:Catie is facilitating nurses in the prevention of burnout andcompassion fatigue in caring for suffering patients over aprolonged period of time by assessing the impact of palliativecare integration into an intensive care unit. She is also lookingat the occurrence of depression in a pulmonary arterialhypertension (PAH) population to better elucidate the need forpalliative care in their treatment. Her aim is to remedy thepaucity of nursing research in the care of pulmonary arterialhypertension patients. Catie enjoys biking, hiking, andspinning. She has been on medical missions to Santiago,Chile, and Ensenada.

Benefits to Society:Up to 1 in 5 Americans die in an ICU setting. Compassionfatigue is a phenomenon that results from expending highlevels of energy and compassion over a prolonged period tothose who are suffering, often without experiencing thepositive outcomes of seeing patients improve. Palliative careproviders becoming involved in ICU care earlier may help toameliorate the helplessness that is often experienced by nursescaring for end-stage patients. Recruiting and sustaining aquality nursing-workforce requires considerable resources.Therefore, steps to prevent nurse burnout or compassionfatigue are a good investment for an organization that placesan emphasis on caring for patients with cancer.

Awards and Honors:Dean's Merit Scholar

UC Center for Health Quality and Innovation Proposal Grant

Sigma Theta Tau

Zeta Mu

Publications and Posters:Madani, C.A. The Incidence of Reperfusion Pulmonary Injury inPatients who have Undergone Pulmonary Endarterectomy:Distal Versus Proximal Disease, 21st World Congress of theWorld Society of Cardio-Thoracic Surgeons, Berlin, Germany,June 12-15, 2011.

Madani, C. Impact of palliative care education and consults onthe incidence of ICU nurses' moral distress. Podium Presentionat the 2012 San Diego Evidence Based Practice Conference.September, 2012.

Madani, C. Impact of palliative care education and consults onthe incidence of ICU nurses' moral distress. PosterPresentation: Sigma Theta Tau International Nursing HonorSociety Odyssey Conference, Nov 2012, Ontario CA.

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JOSEPH NAGANOThe Scripps Research InstituteThe Kellogg School of Science andTechnology

Degrees:B.S. in Chemistry, Brown University

Scholar Sponsors:Reuben H. Fleet Foundation Fund

About the Scholar:Joe’s research focuses on the development of irreversible,covalent inhibitors for various metabolic enzymes in the serinehydrolase super-family. Using activity based protein profilingcoupled with medicinal chemistry, selective inhibitors ofindividual serine hydrolases can be developed in a high-throughput manner. These inhibitors can be used in mouse andcellular models to down-regulate the activity of the targetenzyme, leading to distinct behavioral, physiological andmetabolic effects. Joe plays on an Ultimate Frisbee team.

Benefits to Society:Joe’s studies will benefit society in providing a better under-standing of biochemical systems related to cardiovasculardisease, cancer, drug metabolism, and brain health. Knowledgeof these molecular systems will allow for smarter developmentof drugs that affect these pathways.

Awards and Honors:Ellen Browning Scripps Foundation Fellowship Award

The Scripps Research Institute Dean’s Fellowship

American Chemical Society Division of Organic Chemistry Summer

Undergraduate Research Fellowship

James J. Burke Jr. Presidential Scholarship

George I. Alden Trust Undergraduate Teaching and Research Award

Publications and Posters:Nagano-Gerace, J.; Seto, C. Towards the synthesis of aSerine/Threonine Phosphatase activity-based probe. 239th ACSNational Meeting, San Francisco, CA., 2010 March 21-25, 2010.

CAMERON NOWZARIUniversity of California, San DiegoJacobs School of Engineering

Degrees:C.Phil in Mechanical Engineering,University of California, San Diego

M.S. in Mechanical Engineering, University of California, San Diego

B.S. in Mechanical Engineering, University of California, Santa Barbara

Scholar Sponsors:Reuben H. Fleet Foundation Fund

About the Scholar:Cameron’s research is in artificial intelligence of robots; mostspecifically, how to efficiently extract information from theworld and optimally use that information. His work will seekout pertinent information only, using this small subset to takedesired actions. Most information that is fed to robots isthrough expensive wireless communication; however,Cameron’s algorithms have the potential of reducing theamount of communication and the energy spent by up to 60-90% of standard methods. He breaks from the intensity of hiswork through travel and weekend camping trips.

Benefits to Society:This research is very necessary to make the theory of net-worked autonomous robots a reality. Without event or self-triggered control, the bandwidth required for communicationbetween two or more agents becomes unrealistic very quickly.With this type of management of information and communi-cation with others only when it is absolutely necessary,engineers can incorporate much larger networks using lessenergy while still maintaining performance.

Awards and Honors:O. Hugo Schuck Best Paper Award for Theory

Best Student Paper Award Finalist

California Space Grant Consortium Graduate Fellowship

Jacobs School of Engineering Alumni Fellowship

Research Expo Semi-Finalist Poster Award

Publications and Posters:Nowzari, C.; Cortes, J. Self-triggered optimal servicing indynamic environments with acyclic structure. IEEE Transactionson Automatic Control, 2012. (under review)

Nowzari, C.; Cortes, J. Self-triggered coordination of roboticnetworks for optimal deployment. Automatica 2012, 48 (6),1077-1087.

Nowzari, C.; Cortes, J. Robust optimal decision policies forservicing targets in acyclic digraphs. Conference on Decisionand Control, Maui, Hawaii, 2012. (in publication)

Nowzari, C.; Cortes, J. Self-triggered coordination of roboticnetworks for optimal deployment. American ControlConference, San Francisco, California, 2011, pp. 1039-1044.

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MORGAN NUNNUniversity of California, San DiegoDepartment of Physical Science

Degrees:B.S. in Chemistry, Georgia Institute of Technology

Scholar Sponsors:ARCS Foundation, Arthur and Jeanette Pratt Memorial Fund

About the Scholar:Morgan’s research includes quantifying water in meteorites andlunar rock samples by extraction of volatiles through stepwisepyrolysis. By measuring the oxygen isotopic ratios in the water,information can be obtained about the formation and equili-bration history of the meteorite parent body or the moon. Theseresults can help determine which processes controlled theformation of our solar system. Morgan enjoys running, reading,traveling and studying other languages.

Benefits to Society:The benefits of Morgan’s research will allow us to moreaccurately predict where water can exist, thereby narrowing thesearch for extraterrestrial planets that could be habitable. AsNASA’s “follow the water” slogan reflects, where there is water,there is likely to be life. Consequently, understanding theformation and distribution of water in our solar system is oneof the most fundamental and important challenges scientistsface today.

Awards and Honors:Zonta International Amelia Earhart Fellowship

HOPE Scholarship Recipient

Dr. Richard W. Fink Memorial Scholarship

Chemical Rubber Company Award in Freshman Chemistry

Publications and Posters:Nunn, M.; Thiemens, M. Oxygen Isotopic Analyses of Water inBjurböle Matrix and Chondrules, 74th Meteoritical SocietyMeeting, London, UK, Aug 8-12, 2011.

JASON OBERGUniversity of California, San DiegoJacobs School of Engineering

Degrees:M.S. in Computer Engineering, Universityof California, San Diego

B.S. in Computer Engineering, University of California, Santa Barbara

Scholar Sponsors:ARCS Foundation

About the Scholar:Jason is researching the security of computer applications thatwe rely on for both our safety and personal health. Theseinclude automobiles, commercial airlines, implantable medicaldevices, and many others. His research resolves part of theproblem by providing techniques and tools for evaluatingsecurity of the hardware in a formal way. This will allow thedesigners of these systems to be confident in the security oftheir hardware, opening the door for more versatile, compact,and secure systems.

Benefits to Society:Developing methods and tools for evaluating the security ofhardware opens the doors for more versatile, compact, andsecure systems. Traditionally, if a designer has two parts of asystem (e.g. user and flight-control system on an airline) whichhave stringent security requirements, he/she simply makes twoof them. This not only makes things physically larger, but alsoincreases the system complexity. Jason’s research takes a stepforward in solving this problem, showing that mix-trustedhardware components can be intertwined in a provably secureway. By showing information-flow isolation, it can be proventhat it is not possible for a less secure device to affect a moresecure one (excluding physical phenomena such as observingthe power consumed). This opens the doors to more versatileand complex systems with strong security. Not only will thisresearch help our current systems become more reliable, butfuture systems will be able to handle aspects of our lives whichwe never thought possible.

Awards and Honors:Harold J. and Mary E. Miller Engineering Scholarship

The International Engineering Consortium William L. EverittAward of Excellence

National Science Foundation Graduate Research Fellowship

Jacobs School of Engineering Undergraduate Mentor

Publications and Posters:Oberg, J; Kastner, R. Information Flow Isolation in a Mix-trustedSystem on Chip. (submitted)

Oberg, J.; Eguro, K.; Bittner, R.; Forin, A. Random decision treebody part recognition using FPGAs. The International Conferenceon Field-Programmable Logic and Applications, 2012

Oberg, J.; Hu, W.; Irturk, A.; Tiwari, M.; Sherwood, T; Kastner, R.Information flow isolation in I2C and USB. In Proceedings ofthe Design Automation Conference, 2011.

Oberg, J.; Hu, W.; Irturk, A.; Tiwari, M.; Sherwood, T; Kastner, R.Theoretical analysis of gate level information flow tracking. InProceedings of the Design Automation Conference, 2010.

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MATTHEW ONDECKUniversity of California, San DiegoJacobs School of Engineering

Degrees:M.S. University of California, San DiegoB.S. Carnegie Mellon University

Scholar Sponsors:Hervey Family Non-endowment Fund

About the Scholar:Matthew is developing a material for use in stem cell researchsimulating disease and developmental states. Stem cellsdifferentiate based on cues within the tissue, one being thetemporal and spatial variance in stiffness of the cell’s substrate.Evidence has shown that the stiffness of diseased ordeveloping tissue behaves dynamically, which is difficult tomodel in in vitro and in vivo stem cell research. His materialimplements dynamic cues that will more accurately mimicthese states, facilitating research to investigate a myriad ofcellular states. Matthew enjoys a variety of activities includingsailing, hiking, and basketball.

Benefits to Society:Critical processes such as development and tumor formationare all based out of dynamically stiffening tissues. Due to thecomplexities of developing a dynamic model, these systemsare rarely simulated, which hinders researchers’ ability to fullyunderstand the mechanisms by which they evolve. The abilityto mimic a variety of dynamic biological substrates will allowstem cell researchers to investigate a myriad of cellular states,such as a myocardial infarction, where the resulting scar tissueis much stiffer than the surrounding heart tissue. The noveltyand innovativeness of this project is poised to contribute to theoverall wealth of knowledge in the scientific and stem cellcommunity.

Awards and Honors:Carnegie Mellon University SURF Fellowship

Intel First-Year Research Experience (IFYRE) Fellowship

Publications and Posters:Habib, A.; Ondeck, M.; Miller, K.; Swaminathan, R.; McHenry,M. Novel solder-magnetic particle composites, their reflowusing AC magnetic fields. IEEE Journal; Trans on Magnetics.2010, 46(6), 2187-90.

Habib, A.H.; Xu, S.; Walker, E.; Ondeck, M.G.; Swaminathan, R.;McHenry, M.E. The role of eddy currents and nanoparticle sizeon AC magnetic field-induced reflow in solder/magneticnanocomposites. J. Appl. Phys. 2012, 111(07B305).

TAWNI PARADISEUniversity of San DiegoSchool of Arts and Sciences

Scholar Sponsors:WD-40 Company, Joyce A. Butler

About the Scholar:Tawni is focusing on green compost to find bacteria that willspeed the decomposition rates of some materials. Whencertain items get dumped into a landfill, it can take a long timefor them to decompose and break down. She is mimicking thecompost setting as it occurs in a landfill, but in a controlledsetting. Accelerating decomposition rates at landfills willimprove the efficiency with inflow and the amount of timematerials spend in the dump. In her spare time, Tawni enjoysbeing with her Alaskan Malamute and her domestic shorthaired cat.

Benefits to Society:When materials decompose, there are bacteria that grow onthe surface of the material that can aid in the decompositionrates. In other words, some bacteria can lessen the time ittakes to break down materials in a landfill. Tawni hopes that bymimicking the landfill environment she will be able to identifybacteria on the surface, and in the future if these identifiedbacterias are added to landfills, they can aid in speeding up thedecomposition rates.

Awards and Honors:National Society of Collegiate Scholars

Alcala Scholarship

University of Technology Sydney Study Abroad ExcellenceScholarship

University of San Diego Dean's List

University of San Diego Alcala Club

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PEARL QUIJADASan Diego State UniversityCollege of Sciences

Degrees:M.S. in Biology emphasis in Physiology, San Diego State UniversityB.S. in Biology, University of California, Riverside

Scholar Sponsors:Kathryn Hattox

About the Scholar:Pearl is studying the signaling and treatments of heart disease.She is focusing on integrating molecular and cellulartechniques in order to advance cellular therapy and mitigatedamage after a heart attack. Her research involves workingwith animal models and determining overall cardiac functionafter treatments by echocardiography and in vivohemodynamics to measure pressure and volumemeasurements. Outside of the laboratory, she enjoys going tothe beach, running, and playing with her dog.

Benefits to Society:Pearl believes that her studies and research will have positiveimplications for society in the future. Cardiovascular diseaseaffects millions of people in the United States, where injuryfrom primary or recurrent heart attacks is the main contributorof heart failure. Researchers and clinicians have beenparticularly interested in adult stem therapy in order to mediatedamage, because not only is it safe, but also it has been provenefficacious in several studies. Although the desired effect ofstem cell therapy often supports modest effects in cardiacfunction, the improvements in patient survival and morale aregreat. Stem cell therapy in combination with traditionalinterventions, such as vascular stents and pharmaceuticaldrugs, can have a long-lasting impact on treating heart injuryand heart failure for society.

Awards and Honors:Provost Award for Outstanding Poster Presentation

National Heart Lung and Blood Graduate ResearchSupplement Grant

President’s Award for Outstanding Oral Presentation StudentResearch Symposium 2012

Publications and Posters:Sussman, M.A.; et al. Myocardial AKT:The Omnipresent Nexus.Physiol Rev. 2011, 91, 3, 1023-1070.

Fischer, K.M.; Din, S.; Gude, N.; Konstandin, M.H.; Wu, W.;Quijada, P.; Sussman, M.A. Cardiac progenitor cell commitment isinhibited by nuclear Akt expression. Cir Res. 2011, 108, 8, 960-70.

Quijada, P; et al. Preservation of myocardial structure isenhanced by Pim-1 engineering of bone marrow cells. Circ.Res. 2012, 111, 1, 77-86.

Mohsin, M; et al. Human cardiac progenitor cells engineeredwith Pim-I kinase enhance myocardial repair. J. Am. Coll.Cardiol. 2012.

GABRIEL REYES-RODRÍGUEZUniversity of California, San DiegoPhysical SciencesDegrees:M.S. in Chemistry, University ofCalifornia, San Diego B.S. in Chemistry, Universidad de Puerto Rico, Río Piedras

Scholar Sponsors:Carlos and Sharon Arbelaez

About the Scholar:Gabriel is studying a novel pathway for incorporatingnucleophiles into aromatics to uncover the unknowns ofchemical reactivity by relating reactivity and isotope effects.The questions asked do not have a direct application to society.Instead, they will become a foundation for further research. Hisproject trains the graduate student to generate questions, solveproblems, to use and learn about instrumentation, and toanalyze data and propose explanations. His outside interestsinclude music, sports, and orchids.

Benefits to Society:Gabriel’s research is important in its contribution to basicresearch. The reaction being studied represents a novelpathway for incorporating nucleophiles into aromatics. Notonly will the results answer important and interesting questionsabout chemical reactivity, but also the project trains thegraduate student to generate questions, solve problems, to useand learn about instrumentation, and to analyze data andpropose explanations. There is a desire to uncover theunknowns of chemical reactivity by relating reactivity andisotope effects, generating very interesting questions that willcontribute to defining novel mechanistic pathways of organicreactions. The questions asked do not aim for directapplication in society. Instead, they will be foundation forfuture research. The answers will be long-lasting and theycould be included in organic chemistry textbooks.

Awards and Honors:Chemistry and Biochemistry Graduate Diversity and Outreach

Award

American Chemical Society Division of Organic ChemistryTravel Award

Isidoro Alberto Colón’s Medal for the Outstanding Student inChemistry

Colegio de Químicos de Puerto Rico Award for 2nd BestChemistry Student of Puerto Rico

Faculty of Natural Sciences Honor Student

Publications and Posters:Perrin, C. L.; Reyes-Rodríguez, G. J. Reactivity of nucleophilestoward a p-benzyne derived from an enediyne, J. Phys. Org.Chem. 2012. doi: 10.1002/poc.2994.

Gioda, A.; Reyes-Rodríguez, G. J.; Santos-Figueroa, G; Collett Jr., J.L.; Decesari, S.; Ramos, M. D. C. K. V.; Netto, H. J. C. B.; Neto, F. R.D. A. and Mayol-Bracero, O. L. Speciation of water-solubleinorganic, organic, and total nitrogen in a background marineenvironment: cloud water, rainwater, and aerosol particles, J.Geophys. Res. 2011, 116, D05203. doi: 10.1029/2010JD015010.

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CHELSEA ROCHMANSan Diego State UniversityCollege of Sciences

Degrees:B.S. in Biology, University of California, San Diego

Scholar Sponsors:Larry & Marti Showley

About the Scholar:Chelsea is studying plastic debris in the ocean because of itsmechanical and chemical consequences to marine organisms.Plastic debris is a problem that is ecosystem-wide and it isimperative to understand it as a medium for pollutants thataffect the health of our oceans and our own species. Byunderstanding the eco-toxicity of plastic debris, policy makerscan be better informed and the public better educated on thedangers associated with plastic debris. Chelsea likes all oceansports and enjoys playing the piano and singing.

Benefits to Society:Plastic debris has both mechanical and chemical consequencesto marine organisms. Chemically, plastics act as a magnet forPersistent Organic Pollutants (POPs), which include pesticides,petroleum residues, and flame-retardants. POPs adsorb intoplastics at magnified concentrations; therefore, plastics can beboth an indicator of chemical pollution and a medium for POPsto enter the food chain. Effective mitigation will requireknowledge about POP accumulation rates, transfer to animalsvia ingestion, and biomagnification in marine food chains.

Awards and Honors:AWIS San Diego Chapter Student Scholarship

NSF Graduate Research Fellowship

PADI Foundation Grant

SoCal SETAC Research Grant Award

Malcolm R Stacey Scholarship

Provost’s Honors

SETAC-ACS Environment Exchange Award

COAST Scholarship

COAST Travel Award

Publications and Posters:Rochman, C.; Hentschel, B.; Teh, S.; Hoh, E. Discarded plasticsand priority pollutants: a multiple stressor in aquatic habitats.American Chemical Society National Conference. Philadelphia,Pennsylvania. Aug, 2012. Invited Lecture.

Rochman, C.; Hentschel, B.; Teh, S.; Hoh, E. Discarded plasticsand priority pollutants: a multiple stressor in aquatic habitats.Ecological Society of America National Conference. Portland,Oregon. Aug, 2012. Invited Lecture.

Rochman, C. Consequences of plastic debris in aquatic habitats.CWEA Annual Conference. Sacramento, California. April, 2012.Invited Plenary Lecture.

KATHLEEN ROGERSUniversity of California, San DiegoSchool of Medicine

Degrees:B.S. in Chemical and BiomolecularEngineering, Johns Hopkins University

Scholar Sponsors:Margaret Roulette

About the Scholar:Kathleen uses computer-aided drug design tools and modelingto discover novel drug leads and investigate new drug deliverysystems. Chemotherapies can cause side effects and toxicitiesthat are often worse than symptoms of the disease. She isfinding innovative, more specific therapies or methods ofdelivery that will make these treatments more tolerable andsafer for patients with cancer or parasitic infections such asChagas disease. After this new information is studied oncomputers, it is confirmed with experimental validation at thebench in a wet lab. Kathleen enjoys recreational forms ofdancing, cooking, and hiking.

Benefits to Society:Kathleen’s projects are related to cancer pharmacology, lookingat two very different drug targets that may provide morespecific, and therefore potentially much less toxic,opportunities for treatment of this wide-spread and devastatingdisease. In addition, one target is still quite an enigma in thefield, so a tool compound that will inhibit its activity specificallywill also help elucidate its precise mechanisms through furtherexperimental studies. Alternatively, the host being studied hasalready shown promise as a molecular carrier that can alsoimprove the selectivity of the drug it carries, including somechemotherapeutic agents with high efficacy but severe toxicitywhen taken in conventional form. Another project includesuncovering small molecules with potential as drugs to treatChagas disease. Currently, there is no FDA-approved treatmentfor this often-debilitating disease, which has been described byexperts in the field as “The New HIV/AIDS of the Americas.”With more tolerable and less toxic therapy options, patientcompliance should increase and he or she should continuetreatment for the entire recommended duration. This not onlybenefits the individual but it also benefits society as a wholebecause it will help decrease the risk of drug resistance amongparasite infections.

Awards and Honors:NIH Pharmacological Sciences Graduate Training Grant

Pharmacology Summer Undergraduate Research Fellowship

Publications and Posters:Rogers, K.; Keränen, H.; Durrant, J.D.; Ratnam,J.; Doak, A.;Arkin, M.R.; McCammon, J.A. Novel cruzain inhibitors for thetreatment of Chagas disease. Chem. Bio. and Drug. Design2012, 80(3), 398–405.

Rogers, K.; Ortiz Sánchez, J.M.; Baron, R.; Fajer, M.; de Oliveira,C.; McCammon, J.A. On the role of dewetting transitions inhost-guest binding free energy calculations. (submitted)

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JOHN B. RUEDASSan Diego State UniversityCollege of Sciences, Center for Microbial Sciences

Degrees:Secondary Science Educator Certificate,University of Texas, El PasoB.S. in Biological Sciences, University of Texas, El Paso

Scholar Sponsors:ARCS Foundation Endowment Fund

About the Scholar:John is researching the replication mechanisms of vesicularstomatitis virus, the prototype virus of the negative-strand RNAviruses. These viruses include significant human pathogens,such as rabies and Ebola. Increased knowledge about howthese viruses replicate themselves in infected cells will lead todevelopment of antiviral drugs and vaccines against this classof viruses. John enjoys participating in sports, playing hisguitar and writing music.

Benefits to Society:Understanding virus replication processes makes it possible toidentify virus-specific targets for antiviral drug development.The rabies and ebola viruses are dangerous and even lethalpathogens, particularly in underdeveloped countries. Each virusin this group depends on its own specific protein, whichcollectively function very similarly despite the varyingpathogenesis of each virus. Most promising, these proteinscarry out ‘virus-specific’ processes, meaning that attacking thisprotein may be possible without significant damage to the hostcell, a key requirement for any antiviral drug. While not enoughis understood about this protein for antiviral development,John hopes to contribute to the overall knowledge needed todevelop strategies of attack against this protein.

Awards and Honors:AGEP First-year Graduate Fellowship

Publications and Posters:Ruedas, J.B.; Perrault, J. Insertion of enhanced greenfluorescent protein in a hinge region of vesicular stomatitisvirus L polymerase protein creates a temperature-sensitivevirus that displays no virion-associated polymerase activity invitro. J. Virol. 2009, 83, 12241-12252.

Ruedas, J.B. Insertion of EGFP between the capping andmethylase domains of vesicular stomatitis virus L protein doesnot abolish polymerase functions or virus growth; 28thAmerican Society for Virology Meeting, Vancouver, Canada,July 11-15, 2009.

Ruedas, J.B. Insertion of EGFP between the capping andmethylase domains of vesicular stomatitis virus L protein doesnot abolish polymerase functions or virus growth; StudentResearch Symposium, San Diego State University.

AARON SATHERThe Scripps Research InstituteThe Kellogg School of Science andTechnology

Degrees:B.S. in Chemistry, University of Oregon

Scholar Sponsors:Virginia Lynch Grady Endowment

About the Scholar:Aaron’s research focuses on the extraction of uranium (uranylion) from water. Recognition of the uranyl ion is a longstandinggoal in the field of coordination chemistry due to the potentialapplications in environmental remediation, metallurgicalextraction, and water purification. As nuclear programs continueto develop around the world, increasingly efficient methods forgathering uranium and processing associated chemical waste areneeded. Aaron enjoys playing his guitar, hiking and is on abasketball team with other graduate students.

Benefits to Society:Recognition of the uranyl ion is a long-standing goal in the fieldof coordination chemistry. To accomplish this, Aaron’s lab hasdeveloped and synthesized molecules that recognize uraniumat low concentrations in the presence of other metals. By takinginto account the size and shape of the uranyl ion, Aaron and hiscolleagues were able to create a molecule that surrounds theuranyl ion, maximizing the interactions between the two. Thedesigned molecules are able to extract uranium from water intoorganic solutions. Additionally, they have modified the mostpromising molecule to create a material which will be used topurify water samples containing uranium (think modified Brita®

filter).

Awards and Honors:Undergraduate Award for Outstanding Achievement in

Organic Chemistry

American Chemical Society Undergraduate Award in Analytical Chemistry

Donald Baxter Fellow

Graduate Student Research Symposium Poster Award

Publications and Posters:Berryman, O.B.; Sather, A.C; Rebek, J. Jr. A deep cavitand witha fluorescent wall functions as an ion sensor. (Submitted toOrganic Letters August 3, 2011).

Berryman, O.B.; Sather, A.C.; Lledo, A.; Rebek, J. Jr. Structureand Function of a Light Responsive Cavitand. (Accepted inAngewandte Chemie August 29, 2011).

Cangelosi, V. M Fontenot, S. A Pitt, M. A Sather, A. C Zakharov,L. N Berryman, O. B Johnson, D. W. Design, Synthesis andcharacterization of self-assembled As2L3 and Sb2L3 cryptands.Dalton Trans. (Submitted by invitation).

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JANELLE SHANEUniversity of California, San DiegoJacobs School of Engineering

Degrees:M.Phil. in Physics, University of St.

Andrews, Scotland

B.S. in Electrical Engineering, Michigan

State University

Scholar Sponsors:ARCS Foundation

About the Scholar:Janelle is working to make computers faster by replacingelectronics-based components with light-based (photonic)components. Photonic connections between different computerchips, or within parts of a single chip, will improve the speed andenergy consumption of the world's computers and networks. Asthe speed increases, the light that carries the data startsexperiencing new optical effects. In her research, Janelle hopesto compensate for the harmful fast optical effects and exploit theones that may be useful. Janelle plays the Irish flute, and islearning old-style Irish dance. She also enjoys hiking, writing,and making jewelry from discarded photonic chips.

Benefits to Society:Computers enable much of today's beneficial technology, andJanelle's lab seeks to make them faster by improving the waytheir components communicate with each other, using fast andenergy-efficient light instead of electronics.

Awards and Honors:National Science Foundation Graduate Research Fellowship

Mondialogo Engineering Project, Finalist

Barry M. Goldwater Scholarship

Alumni Distinguished Scholarship

Most Outstanding Electrical and Computer Engineering Student, Michigan State University

Distinguished Service Award, Department of Electrical and Computer Engineering, Michigan State University

Publications and Posters:Shane, J.; Mazilu, M.; Lee, W. M.; Dholakia, K. Effect of pulsetemporal shape on optical trapping and impulse transfer usingultrashort pulsed lasers. Optics Express 2010, 18(7), 7554-7568.

Harris, D. A.; Shane, J. C.; Lozovoy, V. V.; Dantus, M. Automatedphase characterization and adaptive pulse compression usingMultiphoton Intrapulse Interference Phase Scan in air. OpticsExpress 2007, 15, 1932-1938.

Shane J.; Lozovoy V.; Dantus M. Binary search space mapping:Getting a picture of coherent laser control. Journal of PhysicalChemistry A 2006, 110, 40, 11388-11391.

Lozovoy, V. V.; Zhu, X.; Gunaratne, T. C.; Harris, D. A.; Shane, J.C.; Dantus, M. Control of molecular fragmentation using binaryphase-shaped femtosecond laser pulses. Journal of PhysicalChemistry A 2006, 7, 2471-2473.

LUCIE NGUYEN SHARPSTENSan Diego State UniversityCollege of Sciences

Degrees:M.S. in Statistics, San Diego State UniversityB.A. in Applied Mathematics, University ofCalifornia, San Diego

Scholar Sponsors:Reuben H. Fleet Foundation Fund

About the Scholar:Lucie is focusing her research on predicting glaucoma pro-gression by correlating tree-based methods in nature toindividual eyes. The goal of this research is to identify specificpatterns within the visual field that have predictive value forglaucomatous progression. Diagnosing the progression ofglaucoma as early as possible is important to countering even-tual blindness. Lucie enjoys reading mystery novels, snow-boarding, hiking and hula dancing. For the past two years shehas been dancing in the award-winning Heali’i’s PolynesianRevue.

Benefits to Society:Using novel statistical tests (classification and regression trees,conditional inference trees, and random forests), Lucy issearching for biomarkers that place a patient with glaucoma at risk for rapid progression. She has been able to determinewhich patients progress most rapidly by using baselinefindings that predict future changes. Developing better pre-dictive methods will allow physicians to treat ‘at risk’ glaucomapatients earlier and more aggressively, but also allow them totake a more conservative approach in patients that are unlikelyto make substantial progress. This should lead to betteroutcomes on a per patient basis (less visual disability in the at-risk patients and fewer medication side effects in the ‘unlikelyto progress’ patients) and better resource allocations within thewider ophthalmic medical system.

Awards and Honors:Computer Science, Engineering and Mathematics Scholarship

Research in Industrial Projects for Students, UCLA

Publications and Posters:Sharpsten,L; Fan, J.J.; Su, X.G.; Demirel, S.; and Levine, R.A.Predicting progressive glaucomatous optic neuropathy usingrandom forest extremely randomized trees based onlongitudinal standard automated perimetry data. InvestigativeOphthalmology & Visual Science. (to be submitted)

Sharpsten, L.; Fan, J.J.; Su, X.G.; Demirel, S.; and Levine, R.A.Predicting glaucoma progression using decision trees forclustered data by goodness of split. Statistical Analysis andData Mining. (submitted)

Robertson, A.M.; Ojeda, V.D.; Nguyen, L.; Lozada, R.; Martinez,G.A.; Strathdee, S.A.; and Patterson, T.L. Reducing harm fromHIV/AIDS misconceptions among female sex workers in Tijuanaand Ciudad Juarez, Mexico: a cross sectional analysis. HarmReduction Journal. (in press)

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LAUREN SHIPPUniversity of California, San DiegoScripps Institution of Oceanography

Degrees:B.A. in Integrative Biology, University ofCalifornia, Berkeley

Scholar Sponsors:The Richard M. Elkus Family, ARCS Foundation

About the Scholar:Lauren’s research is to advance basic knowledge of how marineinvertebrates deal with toxicants, in order to better understandthe cellular processes that mediate chemical defenses. Herstudies will contribute to a better understanding of whichchemicals should be strongly regulated and what biologicalprocesses are particularly vulnerable to chemical pollution.This knowledge can be used to improve policies that manageindustrial chemicals in the ocean. Lauren is a former gymnastwho now enjoys swimming, gardening, and playing the pianowhen not in the lab.

Benefits to Society:The number of industrial chemicals produced today far exceedsthe capacity of regulatory bodies to test their biological effectsand environmental penetration. There is a significant gap inour knowledge of which new chemicals will bebioaccumulative, persistent pollutants, or otherwise especiallyhazardous. To begin to fill this gap, Lauren’s goal is to advancebasic knowledge of how marine invertebrates deal withtoxicants, and to better understand the cellular processes thatmediate chemical defenses. Her studies will contribute to abetter understanding of which chemicals should be stronglyregulated and what biological processes are particularlyvulnerable to chemical pollution. This knowledge can then beused to improve policies that manage industrial chemicals inthe oceans.

Awards and Honors:National Science Foundation Graduate Research Fellowship

National Defense Science and Engineering Graduate Fellowship

Undergraduate Research Apprenticeship Program SummerFellowship, UC Berkeley

NCAA Academic All-American

NCAA Athletic Scholarship, Gymnastics, UC Berkeley

Publications and Posters:Shipp, L.E.; Hamdoun, A. ATP-binding cassette (ABC) trans-porter expression and localization in sea urchin development.Dev. Dyn. 2012, 241(6), 1111-1124.

Shipp, L.E.; Lee, J.V.; Yu, C.Y.; Pufall, M.; Zhang, P.; Scott, D.K.;Wang, J.C. Transcriptional regulation of human dual specificityprotein phosphatase 1 (DUSP1) gene by glucocorticoids. PLoSOne. 2010, 5(10), e13754.

Koliwad, S.K.; Kuo, T.; Shipp, L.E.; Gray, N.E.; Backhed, F.; So, A.Y.;Farese, R.V. Jr.; Wang, J.C. Angiopoietin-like 4 (ANGPTL4, fasting-induced adipose factor) is a direct glucocorticoid receptor targetand participates in glucocorticoid-regulated triglyceridemetabolism. J. Biol. Chem. 2009, 284(38), 25593-601.

JOSHUA SILVERMANThe Scripps Research InstituteKellogg School of Science and Technology

Degrees:B.S. in Physics, Duke University

Scholar Sponsors:ARCS Foundation

About the Scholar:Josh is focusing on strategies that a cell uses to grow andsurvive according to what resources are available and thecondition of its environment. Different circumstances call fordifferent cells, so cells must morph to fit the situation. Usingglobal surveillance of the proteins that make up the cell massof the proteome, he performs experiments to observe themanagement of the proteome in response to different stressesand energy sources. This has implications for understandingcancer, treating bacterial infections as well as the optimalexpression of genes in the design of cellbased biofuels. Josh enjoys playing softball and plays often.

Benefits to Society:The strategies used by cells for maintenance of or transitionbetween growth phases should underlay all cells. Cancer inmammals, in at least some ways, reflects the reversion ofdifferentiated cells towards single cell behavior as well as thesignificant redesign of the proteome in order to facilitateproliferation. For instance, for an E. coli cell to grow at thefastest rate, it must devote a maximum portion of its proteometo ribosomal proteins, at the expense of metabolic enzymes.Understanding these strategies of proteome management interms of rules and constraints will give a much clearer pictureof what a cell can and cannot do in attempts to switch growthstates. This has implications for understanding cancer, treatingbacterial infections, as well as in the optimal expression ofgenes in the effort to design cellbased biofuels.

Publications and Posters:Chen, S.; Silverman, J.; Sperling, E.; Williamson, J. Dynamics ofribosome biogenesis in E. coli using in vivo pulse labeling andquantitative mass spectrometry. (In submission).

Silverman, J.; Changes in proteome allocation with growthrate: theory and experiment, TSRI Graduate Symposium, 2010.

Silverman, J.; Self assembling DNA networks, MolecularBiomimetics & Bionanotechnology Conference, University ofWashington, 2009.

Silverman, J.; Novel miRNA: Just a few clicks away, ColdSpring Harbor Laboratory Undergraduate ResearchSymposium, 2007.

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CHRISTINE SLOANUniversity of San DiegoHahn School of Nursing and Health ScienceDegrees:M.S.N. in Nursing Education, Point LomaNazarene UniversityB.S.N. in Nursing, University of Arizona

Scholar Sponsors:The Donald C. and Elizabeth M. Dickinson Foundation

About the Scholar:Christine’s research will focus on implementation of palliativecare in the pediatric population. Palliative care offers a holisticapproach to aggressively treating and managing distressingphysical and psychological symptoms, focusing on comfort andquality of life. Despite best efforts some children succumb totheir disease or condition. Parents and caregivers often viewpalliative care measures as “giving up.” As a result childrenoften receive more aggressive and futile care at end of life.Christine enjoys spending time on their sailboat.

Benefits to Society:Despite our technological and scientific advances, not allchildren with a life-threatening illness can be saved. Christine’sobjectives are to explore barriers to obtaining and providingpalliative care, to evaluate the impact of palliative care onpatients and their families, and ultimately, to reduce suffering.

Publications and Posters:Holt, D.M.; Lewis, C.; Klimpel, K.; Sloan, C.; Aguda, C. Theeffects of focused nursing education on 3F Groshong PICCocclusion rates: The experience of one tertiary care facility.Journal of the Association of Vascular Access 2011, 15, 4, 204-212.

Meisenberg, B.R.; Callaghan, M.; Sloan, C.; Sampson, L.; Miller,W.E.; McMillan, R. Complications associated with centralvenous catheters used for the collection of peripheral bloodprogenitor cells to support high-dose chemotherapy andautologous stem cell rescue. Supportive Care in Cancer 1997, 5,3, 223-227.

Meisenberg, B.R.; Miller, W.E.; McMillan, R.; Callaghan, M.;Sloan, C.; Brehm. T, Kosty, M.P.; Kroener,J.; Longmire, R.; Saven,A.; Piro, L.D. Outpatient high-dose chemotherapy withautologous stem-cell rescue for hematologic andnonhematologic malignancies. Journal of Clinical Oncology1997, 15, 1, 11-17.

Sloan, C. The Effect of a Unit-Based Palliative Care Program onEnd-of-Life Variables Among Children with Cancer. PediatricNursing Conference, Orlando, FL; 2009.

MATTHEW BRONSON DE STADLERUniversity of California, San DiegoJacobs School of Engineering

Degrees:M.S. in Engineering Sciences, Universityof California, San DiegoB.S. in Aerospace Engineering, Universityof Virginia

Scholar Sponsors:Wally Schirra Memorial Endowment

About the Scholar:Matthew is using numerical simulations to study turbulenceand turbulent phenomena in the ocean and atmosphere. Thewake behind even a simple object exhibits highly non-linearthree-dimensional unsteady motion. The presence of abackground density gradient further complicates matters as itinhibits vertical motion, allows for the existence of internalwaves that transport energy from the wake to the background,and introduces a complex coupling between kinetic andpotential energy. A better understanding of turbulence will leadto improved engineering tools for the design of a variety ofapplications. Matthew enjoys cooking, swimming, and art.

Benefits to Society:All bodies moving in a fluid leave a wake behind them, orequivalently, flow past a body leaves a wake behind the body.Therefore, wakes are found all over the natural world and inmany engineering applications. Better understanding of thewake behind islands and mountains will lead to improvedclimate modeling, which will allow for improved weatherforecasting. The wake behind vehicles such as automobiles,airplanes and submarines is important for determining the dragand improving vehicle efficiency and sustainability. In additionto these two areas, improved understanding of turbulence willlead to improved turbulence models, which will lead toimproved engineering tools for the design of a wide variety ofapplications.

Awards and Honors:Gordon Scholar, UCSD Engineering Leadership Program

Jacobs Fellow, UCSD

US Department of Defense, National Defense Science andEngineering Graduate Fellow

Publications and Posters:de Stadler, M.B.; Sarkar, S. Simulation of a propelled wake withmoderate excess momentum in a stratified fluid. Journal ofFluid Mechanics, 2012, 692, 28-52.

de Stadler, M.B.; Sarkar, S.; Brucker, K.A. Effect of the Prandtlnumber on a stratified turbulent wake. Physics of Fluids, 2010,22, 095102.

de Stadler, M. B.; Sarkar, S. Self-propelled wakes at differentFroude numbers in a stratified fluid. In TSFP7, Ottawa, Canada,July 28-31, 2011 [CD-ROM]; Seventh International Symposium onTurbulence and Shear Flow Phenomena, Ottawa, Canada, 2011.

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JOHN TAT The Scripps Research InstituteKellogg School of Science and Technology

Degrees:B.A. in History, University of California,San DiegoB.S. in Physiology and Neuroscience,University of California, San Diego

Scholar Sponsors:ARCS Foundation

About the Scholar:John’s research focuses on using CKs protein over-expressionin breast cancer as a biomarker for research and developmentof a novel anti-breast cancer therapy. This proposed therapywill not only provide a means to exert maximal cytotoxicityagainst certain breast tumors, but also generate minimaltoxicity on healthy, proliferating cells, therefore minimizing theadverse side effects such as anemia, dry mouth, and alopecia.In his leisure time John enjoys running and mentoring youngerstudents.

Benefits to Society:The gold standard of breast cancer research is to createtherapies that will selectively kill breast cancer cells from abackground of healthy cells, thereby minimizing the adverseside effects a patient must endure. To achieve this goal,researchers need to identify markers and/or mechanisms thatmake a breast cancer cell different. Cyclin-dependent kinasesubunits (Cks 1 and Cks2) frequently occur in breast cancer andhave been linked to poorer clinical prognoses. Validation ofthis hypothesis in tissue culture works and animal studies willtake us one step closer to personalized medicine in terms ofbreast cancer treatment where cytotoxicity against breastcancer cells is maximized while systemic toxicity is minimized.

Awards and Honors:Richard G. Lambert Foundation for Education Pre-doctoral

Fellowship

UCSD Biological Sciences Student Association Service Award

Armin Rappaport Prize

Erion Scholarship

Change A Life Foundation Scholarship

Publications and Posters:Duong, J; Tat, J; Sadler, GR. The story of two tumors, San DiegoChinese Tribune, 22 Nov. 2008:C6.

Tat, J; Wu, P; Sadler, GR. Children’s advise, We Chinese inAmerica Weekend, 24 Oct. 2008(C) No.95:20.

GINGER TSUENGSan Diego State UniversityCollege of Sciences

Degrees:B.S. in Biochemistry and Cell Biology,University of California, San DiegoB.S. in Psychology, University of California, San Diego

Scholar Sponsors:Virginia Lynch Grady Endowment

About the Scholar:Ginger is studying how coxsackievirus can persist in the brain,and how this ultimately affects behavior. Our bodies clearharmful microbes from the brain and the heart, butcoxsackievirus manages to stay in both long after the initialinfection. By understanding how the body reacts to thepresence of the virus and how the virus is altered by the bodytrying to clear it, scientists can develop knowledge of its long-term effects and of how it may be altering the aging brain.Ginger’s hobbies include web, video and image editing.

Benefits to Society:Ginger hopes her studies on neural stem cell infections mighthelp elucidate how early childhood infections may lead todevelopmental disorders later in life. She also hopes tounderstand how infectious agents may persist/hide in the brainso that when people are treated for immunological diseases,they are not inadvertently put at risk of dying from anypersistent/hidden viruses.

Awards and Honors:Inamori Fellowship, Inamori Foundation

Gen-Probe Fellowship for Ph.D. and M.B.A. Students

Publications and Posters:Tsueng, G.; Tabor-Godwin, J.M.; Gopal, A.; Ruller, C.M.; Deline,S.; An, N.; Frausto, R.F.; Milner, R.; Crocker, S.J.; Whitton, J.L.;Feuer, R. Coxsackievirus preferentially replicates and inducescytopathic effects in undifferentiated neural progenitor cells. JVirol. 2011, 85(12), 5718-5732.

Rhoades, R.E.; Tabor-Godwin, J.M.; Tsueng, G.; Feuer, R.Enterovirus infections of the central nervous system. Virology2011, 411(2), 288-305.

Tsueng, G.; Lam, K.S. A preliminary investigation on thegrowth requirement for monovalent cations, divalent cationsand medium ionic strength of marine actinomycete Salinispora.Appl Microbiol Biotechnol. 2010, 86(5), 1525-1534.

Tsueng, G.; Lam, K.S. Effect of cobalt and vitamin B12 on theproduction of salinosporamides by Salinispora tropica. JAntibiot (Tokyo). 2009, 62(4), 213-216.

Manam, R.R.; Macherla, V.R.; Tsueng, G.; Dring, C.W.; Weiss, J.;Neuteboom, S.T.; Lam, K.S.; Potts, B.C. Antiprotealide is anatural product. J Nat Prod. 2009, 72(2), 295-297.

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LUDOVIC VINCENTUniversity of California, San DiegoJacobs School of Engineering

Degrees:B.S.E. in Bioengineering, University of Pennsylvania

Scholar Sponsors:The Legler Benbough Foundation

About the Scholar:Ludovic is focusing his research on the regenerative potential ofadult stem cells found in human marrow and fat. His project aimis to mimic the environment around stem cells, especially thestiffness, composition, and structure, to better understand cellmigration and to selectively guide these stem cells into musclecells for the eventual treatment of muscle wasting diseases suchas muscular dystrophy. Ludovic enjoys competing in enduranceevents, specifically marathons and triathlons.

Benefits to Society:Understanding how stem cells “feel” their environment andmigrate as a response to physical and chemical cues helpsscientists comprehend how cells home to damaged anddiseased tissues. Equally important is how the stem cell’senvironment dictates the ultimate cell type, i.e. muscle, bone,fat, that these stem cells become in diseased environments andtheir participation in tissue regeneration. Such fundamentalunderstanding is largely lacking and could prove beneficial totreat fibrotic muscle diseases and help devise strategies to treatheart muscle after a heart attack.

Awards and Honors:National Science Foundation Graduate Research Fellow

Herman P. Schwan Bioengineering Award

Publications and Posters:Choi, Y. S.; Vincent, L. G.; Lee, A. R.; Dobke, M. K.; Engler, A. J.,Mechanical derivation of functional myotubes from adipose-derived stem cells. Biomaterials 2012.

Choi, Y. S.; Vincent, L. G.; Lee, A. R.; Kretchmer, K. C.;Chirasatitsin, S.; Dobke, M. K.; Engler, A. J., The alignment andfusion assembly of adipose-derived stem cells on mechanicallypatterned matrices. Biomaterials 2012.

Zubair, A.; Burbelo, P. D.; Vincent, L. G.; Iadarola, M. J.; Smith, P.D.; and Morgan, N. Y. Microfluidic LIPS for serum antibodydetection: demonstration of a rapid test for HSV-2 infection.Biomedical Microdevices 2011.

Vincent, L.; and Engler, A.J. Effect of substrate modulus on cellfunction and differentiation. In Comprehensive Biomaterials,Healy, K.E.; Ducheyne, P.; and J. Kirkpatrick, Ed.; Elsevier: NewYork, 2011.

Metter, R. B.; Ifkovits, J. L.; Hou, K.; Vincent, L.; Hsu, B.; Wang,L.; et al. Biodegradable fibrous scaffolds with diverse propertiesby electrospinning candidates from a combinatorial macromerlibrary. Acta Biomaterialia 2010.

STAN WALLSSan Diego State UniversityCollege of Sciences

Degrees:B.S. in Biochemistry, CaliforniaPolytechnic State University, San LuisObispo

Scholar Sponsors:Hervey Family Non-endowment Fund

About the Scholar:Stan is researching the underlying mechanisms relating obesityand cardiovascular disease at the molecular level. By under-standing the novel molecular links between obesity and cardio-vascular disease, new metabolic markers can be developed toassess cardiovascular risk in overweight and obese individuals,resulting in novel therapeutic approaches to treat obesity andobesity-related cardiovascular disease. Stan’s other interestsinclude creative writing, gardening and playing the guitar.

Benefits to Society:Obesity is defined as a condition of excess weight gain whichincreases the risk for conditions like type 2 diabetes and heartdisease. It is well known that a high-calorie diet rich insaturated fats contributes to excessive weight gain. However,the role that saturated fats play in this process goes far beyondsimple storage in fat tissue. Research in Stan’s lab suggeststhat saturated fats may actually be encouraging the body to eat more food and burn less fat. His research will expand theunderstanding of the deleterious effects of diets high insaturated fat in both the onset of obesity and heart disease.

Awards and Honors:International Research Scholarship

Rees-Stealy Foundation Fellowship

Graduate Student Representative

AHA Predoctoral Fellowship

Publications and Posters:Walls, S. et. al. Identification of Sphingolipid Metabolites thatinduce Obesity in flies via Misregulation of Caloric Intake andFat Storage Mobilization. (In Review)

Walls, S. et.al. Disruptions in Sphingolipid metabolism induceDiabetic Cardiomyopathy in Drosophila. (In Progress)

Tape, K.; Walls, S.; Champlin, L.; Harris, G. Involvement ofSphingolipid Metabolism in the Regulation of SREBPprocessing in adult Drosophila melanogaster. (In Progress)

Wadum, M.; Walls, S.; Harris, G.; Knudsen, J. Disruption ofACBP expression alters fat metabolism, ovulation plus musclefunction and patterning in Drosophila melanogaster. (InResubmission) (In Progress)

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KATHERINE WALSHUniversity of California, San DiegoPhysical Sciences

Degrees:B.A. in Mathematics, George WashingtonUniversityM.A. in Mathematics, University of California, San Diego

Scholar Sponsors:Virginia Lynch Grady Endowment

About the Scholar:Katherine is studying the Hyperbolic Volume Conjecture thatcomes up in knot theory. Knot theory is the study of knots likethose you tie on a string, but with the ends connected so thatyou have a complete circle. The Hyperbolic Volume Conjecturewill help us understand the connection between the intrinsicgeometry of the knot and its different diagrams. Knot theoryhas important connections with higher-dimensional shapes andespecially in geometrical physics. Katherine enjoys hiking,kayaking, and other outdoor activities.

Benefits to Society:Whenever there is an open question, mathematicians like topush it to the end of the line and then a bit farther. Knottheory was studied for a long time without any knownapplications until it was later applied to the study of DNA.The research Katherine is doing now is important to knottheory within itself, since not much is known about thecoefficients of the Colored Jones Polynomial and theirconnection with the Hyperbolic Volume Conjecture. It mayalso become important to a wider range of study, especiallyin geometrical physics, as we learn more about it.

Awards and Honors:Association of Women in Mathematics, UCSD Chapter

President

Invited Graduate Student and Panelist at the NebraskaConference for Undergraduate Women in Mathematics,University of Nebraska-Lincoln

Publications and Posters:Cull, P.; Walsh, K.; Wherry, J. Stability and Instability in OneDimensional Population Models. Scientiae MathematicaeJaponicae (online) 2008, 29–48.

SPENCER WEIUniversity of California, San DiegoSchool of Medicine

Degrees:B.A. in Molecular and Cell Biology,Emphasis in Genetics, University ofCalifornia, Berkeley

Scholar Sponsors:ARCS Foundation

About the Scholar:Spencer is researching how increasing tissue stiffnesspromotes breast tumor metastasis and is identifying thefactors that are involved in this process. Understandinghow these events unfold (what goes awry in cancer cells)during carcinogenesis may lead to the development oftreatments for prevention of tumor metastasis and aid inthe diagnosis of aggressive breast tumors. Spencer enjoysoutdoor activities including basketball, football, cycling andsoccer.

Benefits to Society:Tissue stiffness and other mechanical signals are poorlydescribed, particularly in terms of their role incarcinogenesis. By understanding the molecular events thatdrive tumor progression and metastasis, scientists may beable to predict, or even prevent, such events fromoccurring. Thus, Spencer’s work may aid in the diagnosis ofaggressive breast tumors and lead to the development ofnovel therapies aimed at preventing breast tumormetastasis. These results will likely apply to other types ofcancers as the relationship between tumor tissue stiffnessand metastasis has been described in other tumor types.This is a particularly attractive goal as the main cause ofmortality in cancer patients is metastasis, so preventing thegrowth of metastasis is of the utmost urgency. Further-more, because the relationship between patient outcome,metastasis, and tumor tissue stiffness correlates well in avariety of cancer types, the therapies developed from thisapproach may be effective in a wide range of patients.

Publications and Posters:Blanvillain, R.; Wei, S.; Wei, P.; Kim, J.H.; Ow, D.W. Stresstolerance to stress escape in plants: role of the OXS2zincfinger transcription factor family. EMBO J. 2011, 30, 18,3812-22.

Wei, S.; Blanvillain, R.; Ow, D.W. Effects of histoneacetylation at the SOC1 locus in Arabidopsis. UC BerkeleyHonors Poster Session, Berkeley, CA.; 2008.

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DANIEL WHISLERUniversity of California, San DiegoJacobs School of Engineering

Degrees:M. S. in Structural Engineering, Universityof California, San DiegoB. S. in Structural Engineering, Universityof California, San Diego

Scholar Sponsors:Reuben H. Fleet Foundation Fund

About the Scholar:Daniel’s research is to develop non-explosive test methodsusing gas and hydraulic powered projectiles that simulate ablast event to quickly and environmentally evaluate armoredpanel design. With no fireball, debris, or dust, he can observehow the panel behaves during the simulated blast event. Hecan quickly provide a performance index, selecting the bestdesigns from dozens of proposed armored systems, savingtime and expense for industry in bringing their next life-savingproduct into service.

Benefits to Society:Protecting personnel and equipment in hostileenvironments requires several rounds of extensive andtime-consuming live blast testing of armored components.With Daniel’s research in non-explosive blast simulation, hecan provide a performance index, selecting the bestdesigns from dozens of proposed armored systems in amatter of weeks, thus saving time and expense for industryin bringing their next life-saving product into service. Andwith additional validation to real blast threat levels, hehopes to reduce or even eliminate one (or more) explosive-based tests, which will further expedite armor panel designand ensure that personnel and equipment will be safeunder current and future threats..

Awards and Honors:Chancellor's Research Scholarship

Research Experience for Undergraduates in Physics

Publications and Posters:Whisler, D.; Chen. A.; Kim, H.; Huson, P.; Asaro, R.Methodology for exciting dynamic shear and momentfailure in composite sandwich beams. Journal of SandwichStructures and Materials, 2012, 14, 365-396.

Whisler, D.; Kim, H. Effect of impactor iadius on iow-velocityimpact damage of glass/epoxy composites. Journal of Com-posite Materials, 2012, DOI:10.1177/0021998312436991.

Qazilbash, M. M.; Burch, K. S.; Whisler, D.; Shrekenhamer,D.; Chae, B. G.; Kim, H. T.; Basov, D. N. Correlated metallicstate of vanadium dioxide. Phys. Rev. B, 2006, 74, 205118.

ROBERT WILSONSan Diego State UniversityCollege of Sciences

Degrees:B.S. in Chemistry, California PolytechnicState University, San Luis Obispo

Scholar Sponsors:Lambert Foundation for Education, ARCS Foundation

About the Scholar:Robert is investigating the synthesis of new gallium andindium nitrogen containing molecules and their possibleapplication as single source precursors for semiconductingnanoparticles. This research could lead to new “soft”chemical routes to colloidal gallium and indium nitridesemiconducting nanoparticles and provide insight into thestructure and bonding of this new family of molecules.These nanoparticles have potential application in lightemitting diode (LED), photovoltaic, and medical imagingtechnology. Robert’s long-term goal is to seek a facultyposition at a research-oriented institution. Robert’s otherinterests include snowboarding, water skiing, and hiking.

Benefits to Society:Colloidal semiconducting nanoparticles are of interest fortheir size-dependent emissive properties, ease of handling,and low-cost deposition options (spin coating, ink-jetprinting, etc.). A promising strategy for the synthesis ofsuch nanoparticles is the high temperature decompositionof a single-source precursor, which contains all of thecomponents of the desired material, in a coordinatingsolvent. Robert seeks to contribute to this field through thesynthesis of new gallium and indium nitrogen containingmolecules, evaluating their utility as single-sourceprecursors to semiconducting nanoparticles. Potentialapplications of gallium nitride nanoparticles include theiruse in light-emitting diode (LED) and photovoltaictechnologies. Indium nitride is thought to emit in the nearinfrared, making indium nitride nanoparticles possiblebiomedical imaging agents..

Publications and Posters:Wilson, R. J.; Jones, J. R.; Bennett, M. V. Gallium-TinNitrogen and Gallium Nitrogen molecules: Unprecedentedexamples of Anionic Ammonia analogues and molecularGallium Nitride. (In Submission)

Wilson, R. J.; Bennett, M. V. Toward a family of Gallium andIndium Nitride containing molecules. 238th ACS NationalMeeting, Washington, DC, United States, August 16-20,2009.

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MATTHEW WINGERTUniversity of California, San DiegoJacobs School of EngineeringDegrees:M.S. in Mechanical Engineering,University of California, San Diego B.S. in Mechanical Engineering,University of California, Santa Barbara

Scholar Sponsors:ARCS Foundation

About the Scholar:Matthew is combining his interest in the traditionalmechanical engineering field of heat transfer and hisinterest in nanotechnology. His goal is to measure thethermal properties of nanomaterials at new size scales, assmall as several nanometers, to improve the understandingof nanoscale heat transport. He has developed newmeasurement techniques 100 times more sensitive thancurrent techniques to measure properties at these scales.By understanding the thermal properties of low thermalconductivities, more efficient thermoelectric devices can bedesigned. Matthew enjoys biking along the coast.

Benefits to Society:The thermal conductivity of one-dimensional nanostructures,such as nanowires, nanotubes, and polymer chains, is ofsignificant interest for understanding nanoscale thermaltransport phenomena as well as for practical applications innanoelectronics, energy conversion, and thermal manage-ment. By understanding the thermal properties of smallsemiconducting nanostructures with low thermal conductivi-ties, more efficient thermoelectric devices could be designed.Thermoelectric devices with higher efficiencies would allowus to harness waste heat from power production, industrialprocesses, and transportation to generate electricity, therebyincreasing the overall energy efficiency of importanteconomic sectors. Meanwhile, with the advent of faster,smaller, and more dense electronic devices, understandingthermal properties of small nanostructures becomesimportant for the design of these future nanoscaleelectronics. Heat dissipation becomes an important designconsideration in these devices, especially in personal hand-held devices, and understanding how heat will flow throughthe basic components is important to their development.

Awards and Honors:Tau Beta Pi

Publications and Posters:Wingert, M. C.; Chen, Z. C. Y.; Dechaumphai, E.; Moon, J.;Kim, J.; Xiang, J.; Chen, R. Thermal conductivity of Ge andGe-Si core-shell nanowires in the phonon confinementregime. Nano Letters 2011, 11, 5507-5513.

Wingert, M. C.; Chen, Z. C. Y.; Kwon, S.; Xiang, J.; Chen, R.Ultra-sensitive thermal conductance measurement of one-dimensional nanostructures enhanced by differentialbridge. Review of Scientific Instruments 2012, 83, 024901.

JENNIFER YOUNGUniversity of California, San DiegoJacobs School of Engineering

Degrees:B.S. in Biomedical Engineering,University of California, Davis

Scholar Sponsors:George Smedes Poyner Foundation

About the Scholar:Jennifer is designing a material for use in treating heartpatients suffering from heart failure. The stiffness of thesubstrate on which a stem cell is placed influences what thecell ultimately differentiates into; this material willdifferentiate stem cells toward heart cells with theappropriate mechanical cues. When the heart fails, thismaterial could be delivered into the site of injury to restoreheart tissue structure and function, providing a betteroutcome for the patient. Jennifer has a wide spectrum ofinterests, such as cooking, baking, traveling, painting,drawing and photography.

Benefits to Society:Heart failure is the leading cause of death in the Westernworld. Currently, there exists no treatment for heart failure.Minimally invasive biomaterial and/or cell treatments couldbe the solution to finding a means to repair the heart, post-heart attack, thereby preventing heart failure and death. Ifthe stem cell/material treatment Jennifer is studying issuccessful in restoring heart structure and function, aprolonged and improved quality of life of the patient willresult. The ideas from her project can also be applied toother areas of cell therapy for many other types of diseasesand disorders. Lastly, Jennifer’s project will contribute to agreater understanding of stem cell biology and theextracellular matrix among the scientific community.

Awards and Honors:American Heart Association Pre-Doctoral Fellow

Publications and Posters:Young, J.L.; Christman, K.L. and Engler, A.J. Stem cells forcardiac tissue engineering. In Stem Cells and TissueEngineering; Li, S. et al.; Eds.; World Scientific PublishingCo. Pte. Ltd.: Hackensack, NJ, 2011.

Young, J.L.; Engler, A.J. Hydrogels with time-dependentmechanical properties enhance cardiomyocytedifferentiation in vitro. Biomaterials 2011, 32(4), 1002-1009.

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DAVID ZIMMERMANNUniversity of California, San DiegoPhysical Sciences

Degrees:M.S. in Mathematics, San Jose StateUniversityB.A. in Mathematics, University ofCalifornia, Berkeley

Scholar Sponsors:Reuben H. Fleet Foundation Fund

About the Scholar:David is studying a family of inequalities called LogarithmicSobolev inequalities that certain mathematical objects, calledmeasures, satisfy. These inequalities are a useful tool in

mathematics with applications to many other areas such asprobability, functional analysis, geometry, and physics. Not allmeasures satisfy a Logarithmic Sobolev inequality. He isshowing that there is a large class of measures that do satisfysuch an inequality. This makes Logarithmic Sobelov inequalitiesa widely applicable tool, so results in these other areas ofmathematics can be proven. David enjoys rock climbing,ultimate Frisbee, and board games.

Benefits to Society:Logarithmic Sobolev inequalities are a useful tool in analysisthat has applications to many areas of mathematics, such asprobability, functional analysis, geometry, and physics.Expanding the class of measures which are known to satisfylogarithmic Sobolev inequalities will increase the applicabilityof this tool, enhancing our ability to discover and prove newresults in these areas.

What Does this Award Mean to You?

Rebecca AschThe extra funding from ARCS has helped mepurchase supplies for my research (including a newcomputer) and has allowed me to present myresearch at national and international conferences.At one of these conferences, I won an award for thebest student presentation.

Patrick BlachlyARCS Foundation Scholar Award has both enabledme to travel home and helped to cover unforeseenexpenses (e.g. auto repairs). These conveniencesbetter allow me to focus on my research withoutsweating the little things in life.

Laura ConnellyARCS Foundation Scholar Award has helped covermy cost of living without having to spend time TA-ing. It has also provided me with the opportunity totravel home to the East coast each year to visit myparents for the holidays.

Chris DeBoeverIt is exciting to see donors continue to supportpromising young scientists during difficultfinancial times. Many of us forego big paychecksto head to graduate school, but still have sizeabledebt from undergraduate degrees. ARCSFoundation Scholar Award lessens this financialburden and allows me to focus on the important(and fun) stuff, the science.

Russ DeKelverAlthough I enjoy graduate school, it is difficult tolive on the stipend in San Diego. I have had tomake some tough financial decisions, and I havemissed out on important holidays and life events(weddings, etc.) of my close friends and familysimply because I could not afford to travel to attendthem. ARCS Foundation Scholar Award will nowallow me to pursue my studies fully and still beable to see my friends and family for theseimportant moments in our lives.

Katie DuncanARCS Foundation Scholar Award helps me make themost of my graduate research experience, givingme freedom and flexibility to tackle difficult andmeaningful problems both inside the laboratory and out.

Jennifer EmondIt is an honor to be acknowledged by ARCSFoundation, and I am proud to be part of such anaccomplished group of students. The financialaward will help me cover child care during thisacademic year so I may continue my dissertationstudies full-time.

Wes GiffordI am honored and cannot bestow enough thanks forthe generous support. The Scholar Award not onlyprovides financial support - it provides genuine

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encouragement, which is always welcome. I alsoconsider this gift an investment into mydevelopment as a physician-scientist, which I takevery seriously. I hope that my work both now andthroughout my career will improve the lives ofpatients suffering from disease.

Charlie GrangerTaking school loans for a higher education isdefinitely worth it, but it's still hard to not thinkabout accruing debt and interest while I helplesslytry to focus on school. This Scholar Award fromARCS Foundation has allowed me to breathe a sighof relief and it will make my concentration on mythesis and applications to Ph.D. programs mucheasier without the thought of growing student loansin the back of my head.

Mike GurneyARCS Foundation Scholar Award will help give mesome flexibility in finding child care, which willafford me more time to contemplate, complete, andpublish my work.

Erilynn HeinrichsenTo be recognized as an ARCS Foundation Scholar isan incredible honor. When you are constantlysurrounded by brilliant scientists, it can be hard tosee yourself ever reaching their level. ReceivingARCS Foundation Scholar Award feels likeverification that yes, I can do this—I may just be agraduate student, but I must be on the right track ifmy PI chose to nominate me and ARCS Foundationchose to recognize me with this Award.

Marcel HetuARCS Foundation Scholar Award has let me focusmore time on research and less time worryingabout how I am going to meet expenses at a timewhen tuition and fees continue to increase whilefunding for graduate students decreases. I havebeen able to attend conferences and have publisheda portion of my work.

Stephanie Huelga ARCS Foundation Scholar Award will allow me toattend scientific conferences worldwide to share myresearch with others and also learn about novelfindings in my field of research.

Manna Iwabuchi The Scholar Award makes it possible for me to payliving expenses so that I can focus on my researchwithout worrying too much about my budget. It is

an honor that motivates me to pursue my degree inscience.

Sarah LeBoeufI am so thankful to be supported by ARCSFoundation. Not only is it an honor to be recog-nized for my scientific achievements, but the ARCSFellowship greatly helps fund and further myeducation.

Katie LeVan Before receiving ARCS Foundation Scholar Award, Iwas concerned about funding from my adviser formy project. Without this Award, I would have hadto do additional teaching responsibilities (20 hoursper week commitment) slowing my academic pro-gress significantly. This ARCS Foundation ScholarAward means that I can spend more time workingon my project and writing up my dissertation for publication.

Connor LindIn reducing the cost of my tuition, ARCSFoundation Scholar Award will allow me to allocatemore time and money to my research and careerinterests.

Catherina MadaniARCS Foundation Scholar Award has allowed me tocontinue with my education full time and allowedme to add vital classes to my curriculum.

Cameron NowzariIt is well known that graduate students get paid (ifat all) very little for the amount of time and workthey put into writing a dissertation and obtaining aPh.D. I love the subject I am researching and trulybelieve it can be very beneficial in advancingtomorrow's technologies. Unfortunately it is hardto stay motivated when I know I can make fourtimes (if not more) the income I currently have bygoing into industry. I have been debating for quitesome time, and still am, about whether to stay inacademia after my Ph.D. and continue my research,which I would love to do, or go to some seeminglymeaningless industry job just to make money.Awards like this are just about the only addedmotivation I have to continuing my research.Winning a Scholar Award like this shows mevalidation that the work I am doing is indeedinteresting and sought after and thus helps push meto continue.

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Continued on Page 38

Jason ObergPrior to receiving this Scholar Award it has beendifficult for me to collaborate with otheruniversities and attend conferences because fundshave been limited for travel. ARCS FoundationScholar Award will help me meet with otheruniversities and attend conferences which willexpand the breadth of my research.

Matthew Ondeck ARCS Foundation funding will be very important tomy career as a young researcher. It will provide methe opportunity to disseminate my researchthrough a variety of journals and symposiums.With ARCS Foundation funding I will attend andpresent my work at the Biomedical EngineeringSociety and Materials Research Society AnnualMeetings, as well as the American Society for CellBiology Conference.

Tawni ParadiseARCS Foundation Scholar Award, and itssignificance is not something that can be shown orexpressed in one or two paragraphs.The Award isnot just extra cash to me or some excuse to slackoff a little more. This money gives me more time tofocus on and observe things I did not have time toobserve before. I currently work part time at a realestate office which provides me with enough fundsto make it through the month with healthy food anda clean house. This Scholar Award allows me to cutmy hours down and spend more time doing thethings I love. This Award means spending moretime contemplating my research and the certainways that it reacts. This Award means spendingmore time with my loving family, and improvingrelationships that I didn't have enough time to keepstrong before. This Award gives me more time tofocus on my studies and to really engage in thelearning experience that I am put in. This Award isnot significant to me because of the amount ofmoney put forth, but because the money allows meto have more time. This time will allow me to focuson my passions in life, my relationships, and mystudies. Although this gives no justice to theimportance and significance of the ARCSFoundation Scholar Award, it is a start in explaininghow important this extra help can be in a youngwoman's life.

Pearl QuijadaARCS Foundation has made a great impact in mylife in the past year. I have made great contacts

with not only my mentor Kathryn Hattox and herhusband Dr. John Hattox, but also with othermembers of ARCS Foundation and Award recipientsacross San Diego. ARCS Scholar Award hassupplemented my cost of living, which in turn easesmy stress and increases my confidence in thelaboratory to perform experiments and write myfirst author publication, which was accepted in the“Journal of Circulation Research,” June 2012. I amgrateful to ARCS Foundation and the Award it hasgiven me for making my graduate schoolexperience productive and successful thus far.

Chelsea M. RochmanARCS Foundation Scholar Award has allowed me toconnect with women who support science in the com-munity and also has allowed me to maintain funds sothat I can focus on research as opposed to bills.

Gabriel Reyes-RodríguezARCS Foundation Scholar Award means a lot to me.The fact that my advisor is an eminence in hisresearch field and he decided to nominate me forthis Award means that he believes in me, and hesees a bright future in my research/teaching career.

Kate RogersBefore receiving the Scholar Award, it was hard tofit a lot of “extras” into my budget, mostimportantly traveling expenses to visit family. Mymother and I are extremely close, so after she wasdiagnosed with lymphoma during my second yearof graduate school, it has been particularly hard tolive away from her and the rest of my family.Overall, ARCS Foundation will help allow me toobtain a better work/life balance and provide thenecessary “wiggle room” in my monthly budget so Ican focus on my research instead of stressing overmy bills. ARCS Foundation Scholar Award not onlygives me peace of mind financially but it also provides a boost of confidence and extraencouragement for the remainder of my Ph.D.career to help propel me toward the finish.

Janelle ShaneARCS Foundation Scholar Award has made me feelsupported and appreciated by my community, andhas given me confidence in the worth of myresearch.

Lucie Sharpsten The Scholar Award has helped me to succeed in mygraduate career, not only financially, but also it gaveme confidence to know I was doing the right things.

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Lauren ShippARCS Foundation Scholar Award will help pay forremaining undergraduate student loans, which Ihave been unable to pay since beginning graduateschool. On a personal level, it is extremelyrewarding to know that my department and advisorsaw enough promise in my work to nominate me,and that ARCS Foundation honored me with theAward. I am extremely grateful for this support andrecognition, and it further motivates me to remaindedicated to my research.

Matthew de StadlerReceiving an ARCS Foundation Scholar Award hasallowed me to focus on research without having toworry about my finances. The financial support hasallowed me to buy necessary resources such astextbooks, attend conferences, and has allowed meto build up my savings to ensure a smoothertransition from graduate school to my next position.In addition to the financial benefits, being named anARCS Foundation Scholar demonstrates to me thatthe work I am doing is important and that there arepeople who believe in me and want me to besuccessful.

John TatIn this economic recession, many labs are sufferingin terms of funding. This problem is experienced byboth established and junior investigators alike. Thefinancial problem unfortunately (but notsurprisingly) extends to graduate students as wellbecause many investigators are having problemssupporting their students. Winning the ARCSFoundation Scholar Award could not have come ata better time for me, as it means that a fraction ofmy stipend will be secured. This will give me moretime to focus on my research work, a project thatmight revolutionize the way we treat breast cancer,rather than worrying about how to secure enoughfunding for my stipend.

Ludovic VincentARCS Foundation Scholar Award was my first everfellowship. It gave me self-confidence andvalidated the work I had put into my field ofstudies. ARCS Foundation Scholar Award also gavecredibility to other grant applications, and led me toreceive a National Science Foundation Fellowship,which funds my tuition and part of my salary, givingme increased freedom over the specific topics of mygraduate studies.

Katherine WalshWith ARCS Foundation Scholar Award I have beenable to travel to more conferences and been able tofocus solely on research for the summer.

Daniel WhislerARCS Foundation Scholar Award means to me thatthere are individuals in this world who see us –scholars, scientists, researchers – and recognize thelong hours and countless frustrations we endure aswe devote our talents and passion to better society.It is easy to forget while setting up elaborate testfixtures and preparing hundreds of specimens, mostof which my family and friends will never see orunderstand, that I have support, that I have peoplewho believe in me to make a difference. Before thisAward, I sold possessions, tutored students, andbought my computers 4-5 years old used off auctionsites. I searched coupon sites for hours on end tosave a few dollars on everyday expenses, and evenmoved back home and carpooled 80 miles each dayfor a year and a half to save money on rent. Withthe Award, I can finally buy a few of tools on mywish list to help me test and graduate! Thank you!

Robert WilsonA doctoral degree in chemistry is a 5-6 year full-timecommitment. The support I have received fromARCS Foundation during this time has allowed meto concentrate on my research, instead of frettingover debt.

Matthew WingertARCS Foundation Scholar Award will allow me thefreedom of mind to focus on my research as well asexpand my research capacity with new equipment.Most importantly, though, I appreciate the recog-nition and support that accompanies this Award.

Jennifer YoungARCS Foundation Scholar Award is such a greathonor. It affords me a greater peace of mind andallows me to better enjoy my time outside of lab.Not only has this Award improved my quality of lifeas a graduate student, but it has given me theopportunity to travel to international conferences.This year, I got to visit China and Japan for theWorld Biomaterials Congress and the InternationalSociety for Stem Cell Research Conference,respectively, two locations I've never visited, andam so thankful for the great academic and culturalexperiences. I have now made internationalcontacts that will be instrumental in my search for apostdoc overseas next year.

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2011-2012 Donor Honor RollSAN DIEGO CHAPTER • JULY 1, 2011 – JUNE 30, 2012

Gifts received for awards to be made in the Academic Year 2012 - 2013

$48,000Reuben H. Fleet

Foundation Fund

$30,000Hervey Family

Non-endowment Fund

$15,000Beyster Family

Foundation Fund IVThe Donald C. & Elizabeth M.

Dickinson FoundationEllen Browning Scripps

Foundation

$10,000Webster & Helen Kinnaird/Paul Bechtner Foundation

$7,500 - $9,999The Thomas C. Ackerman

FoundationCarlos & Sharon Arbelaez

The Legler BenboughFoundation

Kenneth & Marjorie BlanchardThe Collins Companies –

Ty & Diane MillerKathryn Crippen Hattox

Cymer, Inc.The Heller Foundation

of San DiegoJackie Linstrom

George Smedes PoynerFoundation

Margaret RouletteThe Jerry D. and CherylSawatzke Routh Family

FoundationLarry & Marti Showley

Timkin-Sturgis FoundationWD-40 Company

$5,000 - $7,499Betty Beyster

The Richard M. Elkus FamilyThe French & Masserini Funds

at Wells FargoUnion Bank

Larry & Mara Ybarrondo

$2,500 - $4,999Joyce A. Butler

The Samuel I. & John Henry Fox Foundation

Susan Hoekenga & Edward Gergosian

Lambert Foundation for Education

Betty L. PeabodyThe Arthur & Jeanette Pratt Memorial Fund

Pat & Bob WhalenHal & Betty Jo Williams

$1,000 - $2,499Janet AllisonAnonymous

BIOCOMKaren & Bob Bowden/Bowden

Family FoundationThe Burnham Foundation

Sue & Howard BusbyJune Chocheles

Cubic CorporationBob & Ann Dynes Charitable Fund

Sally & Parker FinchWillis & Jane Fletcher

Family Fund IINancy Reed Gibson

Bea HadingerHank & Betty Harriman

Susan HeavilinAndy & Karen Hewitt

Peter HoDr. & Mrs. E. Woodrow Hunt

Mrs. David A. JamesAnn Lemke

VADM & Mrs. William McCauleyDr. & Mrs. William McColl

Dan & Mary MulvihillJanet & Craig Munson

Dale & Marge Myers FundPam & Phil Palisoul

Marti & Frank PanarisiChan Poyner Pike

Thomas & Audrey PineFoundation

Gloria McColl PowellDr. Jane K. Smith

Patricia Brander StewartDr. & Mrs. Blake Talbot

Honorable & Mrs. GordonThompson, Jr.

RADM & Mrs. Guy Zeller

$500 - $999Barbara & Charles Arledge

Lois & Dan BakerNancy & Mo Bildsoe

Doris & Peter EllsworthBecki & Edward Etess

Joan & Milt Evangelou

Dave & Mary FitzJeanette & Bobby Foushee

Dottie GeorgensChristine Gutheil

Sandra HarrisJim & Barbara Hartung

Nancy & David HerringtonMaureen Lamberti

Bess LambronThe Hal & Mary Sadler

Family FoundationJerrie & Jim Schmidt

Richard & Bobbie VandervoortCapt. & Mrs. Don Waggoner

UP TO $499Kate Adams

Connie & James AdelmanNancy Anderson

AnonymousEmily Bagnall

John & Ann BakerMarla Black

Bob & Marcia BorgmanBetty Brayshay

Aubrey & Judy BurerRonald D. BurgessDiane A. Chalmers

Virginia ChaseyJean & Michael Collins

Kim ConnerAndrea L. Correnti

Ruth CovellMarijeanne Crabtree

Walter & Barbara DorenBerit Durler

German Eichberger & Emilia Olson

Karen FontanaJoy B. FryePatty FullerHolli Garrett

General AtomicsShirley Godwin

Barbara & David Groce FundPeggy Hanley Phyllis HaynesMarge Hebert

Col. & Mrs. William HerrinNorma Hidalgo del Rio

Nigella HillgarthSandra Fleet Honnen

HP Company FoundationElizabeth Hubbard

Richard & Cynthia JacksonSusan B. Jones

Lee & JoAnn KnutsonCandace Kohl

Heather Kowalski & J. Craig Venter

Dan & Yvonne LarsenJeanne & Bill Larson

Katherine LeeSharon LeeMaster

Joan & John LightnerRobin & Chuck Luby

Karen LudwigDeborah & Fred Mandabach

Diane MarinosLynne Martin

Adrienne McCulloughWilliam & Carol McDade

Kimberly MillerHelga Moore

Priscilla L. MoxleyPeg Neuhauser

Toni NickellAlice Oslund & Glenn Hittner

Louise PelanSusan Pondrom

Mary Lou & Harry QuickPaula Ray

Katherine RedmondAnn Rible

Edwina & Roy RibletLois S. Roon

Astrid ShannonJanice ShawAnn SiemansAnn SillimanLeslie Smart

Dr. & Mrs. Meredith SmithIlene E. Swartz

Karen & Donald TartrePaula Taylor & Bernie Kulchin

Walter and Joan ThulinEleanor H. Tobin

Camille UhlirMr. & Mrs. Peter R. Vincent

Yolanda Walther-MeadePattie Wellborn

Jack & Judy WhiteMary Jane Wiesler

Joan G. WilsonMargaret & John Wood

Clayton & Cristena YeutterBeverly & Allan Zukor

=The San Diego Foundation

= Fund managed by Union Bank

The amounts above include donationsto the ARCS Foundation ScholarAward Fund, Endowment, and

Memorial Funds as of June 30, 2012.

40

C,* Kate AdamsConnie AdelmanJanet Allison

C,* Nancy Anderson* Mary Beall Angel

Sharon ArbelaezC,* Barbara Arledge

* Katherine ArmagnacHE Rita Atkinson

Ann Baker* Elisabeth Beck* Pat Beck* Betty Beyster* Judy Bieler

Nancy BildsoeMarla BlackMarcia Borgman

F Karen BowdenBetty BrayshayAlice Brown

C Kathleen BuoymasterJudy Burer

* Sue Busby* Joyce Butler

Diane ChalmersC Virginia Chasey

Jean Collins* Linda Copson

Andrea CorrentiDarlene DaviesCarolyn Detwiler

* Carol DickinsonSuzanne Dixon

* Barbara DorenBerit DurlerAnn DynesPatty Elkus

* Carolyn Elledge* Peggy ElliottE Doris Ellsworth* Becki Lamont Etess C Joan Evangelou

C,* Jane Fetter* Sally Finch

Mary Fitz* Georg’Ann Fletcher* Karen Fontana

Jeanette FousheeHE Marye Anne Fox

Joy FryePatricia FullerHolli Garrett

C,E Dottie Georgens* Nancy Reed Gibson

Shirley GodwinDiane GreggBarbara GroceChristine GutheilBeatrice Hadinger Peggy Hanley

* Betty Harriman Sandra HarrisBarbara Hartung

* Kathryn Crippen HattoxPhyllis HaynesHolly HeatonMarge HebertJoanne Herrin

* Nancy HerringtonNorma Hidalgo Del Rio

* Ann HillNigella Hillgarth

H Jeri Hirshman * Susan Hoekenga* Sandra Fleet Honnen* Elizabeth Hubbard* Coley Hunt* Ethel Iverson

LOA Cynthia Jackson* Nancy James

Kim JohnsonSusan Jones

* Helen KinnairdCandace KohlMaureen Lamberti

* Bess LambronC Yvonne Larsen

Jeanne Hancock LarsonLOA,* Sharon LeeMaster

* Ann LemkeHE Nicola Green Lerner

* Jacqueline LinstromRobin Luby

F Karon LuceKaren Ludwig

H Mary E. LyonsDeborah MandabachDiane MarinosLynne MartinMary Ann McCauley

F Barbara McColl* Gloria D. McColl Powell

Adrienne McCullough* Carol McDade

C,* Diane MillerKimberly MillerHelga S. MoorePriscilla Moxley

* Mary Mulvihill * Janet Munson

LOA Holly NappenE Toni Woodward Nickell

Pamela PalisoulMarti PanarisiBetty Peabody

LOA Louise Pelan * Chan Poyner Pike

Sue PondromMary Lou Quick

C,E Paula RayLOA Katherine Redmond

Edwina Riblet* Charlene Rights* Margaret Roulette* Mary Sadler

C,E Jerrie Schmidt* Astrid Shannon

Jan ShawMarti ShowleyAnn E. SiemensAnn Silliman

E Betty SimmJane Smith

* Patricia Brander StewartIlene Swartz

* Jean TalbotKaren M. Tartre

C,* Jean ThompsonLois S. ThompsonJoan ThulinBobbie VandervoortCarolyn WaggonerYolanda Walther-Meade

HE Susan Keim WeberF Pattie Wellborn* Patricia Havill Whalen

Judy WheatleyC,* Betty Jo Williams

Christina WilsonC,HE Gayle Wilson

C Joan G. Wilson * Christie Wright* Mara Ybarrondo

Britt Zeller

*=Associate, C=Charter, E=Emeritus, H=Honorary, HE=Honorary Emeritus, LOA=Leave of Absence154 Members

2012-2013 ARCS® Membership

For more information, please contact:

Robin Luby PHONE (858) 459-9455 | FAX (858) 459-7187

rbluby@earthlink.net

San Diego ChapterP. O. Box 8394, Rancho Santa Fe, CA 92067-8394

sandiego@arcsfoundation.org

San DiegoAwards to date: $7,579,500Scholars to date: 4862012-2013 Awards: $397,5002012-2013 Scholars: 57Current Schools: 4Members: 154

NationalAwards to date: $82,828,057Scholars to date: 14,1882011-2012 Awards: $4,117,4882011-2012 Scholars: 528Current Schools: 55National Members: 1,559