abdominal pain in the elderly kevin biese, md, mat ellen roberts, phd, mph jan busby-whitehead, md...
TRANSCRIPT
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ABDOMINAL PAIN IN THE ELDERLY
Kevin Biese, MD, MATEllen Roberts, PhD, MPH
Jan Busby-Whitehead, MD
University of North Carolina at Chapel HillDivision of Geriatric MedicineCenter for Aging and Health
Department of Emergency Medicine
THE AMERICAN GERIATRICS SOCIETY
Geriatrics Health Professionals.
Leading change. Improving care for older adults.
AGS
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OBJECTIVES
• To increase appreciation of the variety of presentations of acute abdominal pathology in elderly patients
• To appreciate the differences in etiology of acute abdominal pain between elderly and younger patients
• To increase proficiency of evaluation and management of elderly patients with acute abdominal pain
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WHY CARE?Increasing Elderly Population (≥65 Years)
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WHY CARE?Significant Mortality and Morbidity
Of patients ≥65 years old who come to the ED with acute abdominal pain:
• 50% admission
• 33% surgery
• 10% mortality (similar to ST-elevation myocardial infarction)
Kizer KW. Am J Emerg Med. 1998;16:357-362.
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CASE 1: MS. JONES
• 85-year-old woman with past medical history of atrial fibrillation, GERD
• Chief complaint: abdominal pain that started 8 hours before arrival, sudden onset
• Intermittent pain, was able to eat dinner 3 hours after onset without difficulty
• Afebrile, vital signs within normal limits (WNL), no vomiting, no diarrhea, normal bowel movement 2 hours before arrival
• Exam: mildly tender epigastric and right upper quadrant (RUQ) region without peritonitis, no Murphy’s sign
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MS. JONES: INITIAL RESULTS
WBC count 11.7
Hematocrit 49
Platelets 193
Chemistries WNL
Liver function tests (LFTs) WNL
Lipase WNL
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GALL BLADDER DISEASE: ARE LFTS HELPFUL?
Total bilirubin, AST, or alkaline phosphate
Positive likelihood ratio
Negative likelihood ratio
All 3 elevated 1.6 0.8
Any 1 elevated 1.2 0.7
Trowbridge RL. JAMA. 2003; 289(1): 80-86.
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MS. JONES ULTRASOUND
Insert ultrasound image of cholecystitis with gall stones,
thickened gall bladder wall, and edema.
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CHOLECYSTITIS
• #1 abdominal surgical emergency in elderly
• Incidence increases with age
• Often only epigastric pain (foregut innervation is visceral)
• LFTs often not helpful
• Ultrasound is study of choice
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CASE 2: MS. JONES RETURNS
• Ms. Jones returns to the ED 4 days post-op
• Chief complaint: RUQ pain
• Pain worsened last night, able to eat, general fatigue
• Vital signs WNL, afebrile
• Moderate tenderness in RUQ
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MS. JONES: THE RETURN VISIT
• Labs including LFTs are WNL
• What to do?
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MS. JONES: THE RETURN VISIT
• The diaphragm is an unsecured border; upper abdominal pain can be
Acute coronary syndrome Pulmonary embolism Pneumonia
Insert CT image of pulmonary embolism
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CASE 3: MS. SMITH
• 80-year-old woman with past medical history of breast cancer, hypothyroidism
• Chief complaint: abdominal pain
• Sudden onset 10 hours before arrival, right lower quadrant (RLQ) pain constant in location, 10/10 intensity, + diarrhea
• Exam notable for moderate RLQ tenderness, Hemoccult negative
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MS. SMITH: APPENDICITIS
Insert CT image of appendicitis.
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APPENDICITIS IN THE ELDERLY
• 5% of acute abdominal cases
• Rarely have the 4 classic criteria (anorexia, elevated WBC, RLQ pain, and fever)
• Diagnosis often missed (presence of diarrhea or WBC in urine can be misleading)
• However, usually have at least RLQ pain
Kauvar DR. Clin Geriatr Med. 1993;9:547-558.Storm-Dickerson TL. Am J Surg. 1983;185:198-201.
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CASE 4: MS. DOE
• 67-year-old woman with HTN, COPD, CAD
• Chief complaint: abdominal pain
• 3 days generalized, intermittent abdominal pain with nausea, vomiting, and diarrhea (n/v/d); no black stools; some urinary hesitancy
• Seen by PCP 2 days prior, given phenergan
• No apparent distress; exam notable for moderate RUQ and RLQ tenderness
• HR 115, BP 160/100, T 37.0
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MS. DOE:INITIAL RESULTS
• WBC 11.5; o/w CBC WNL• Chemistries 7 and LFTs WNL• UA shows 7 WBC, nitrite negative• Arterial lactate 1.0
• What to do? A diagnostic test was obtained several hours
later…
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LearningRadiology.com, retrieved June 1, 2011. Slide 18
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MESENTERIC ISCHEMIA
• Classically, pain out of proportion to exam
• Risks include atrial fibrillation, hypercoagulable, low-flow, increasing age
• Usually arterial; may be venous
• Embolus or thrombosis
• Sometimes “intestinal angina”
• Usually superior mesenteric artery
• Multidetector CT scan 77%90% sensitive
• Elevated lactate is a late finding (check >1 time)
Newman TS. Am Surg. 1998;64:611-616.Horton KM. Radiographics. 2002:22;161.
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CASE 5: MR. SMITH
• 82-year-old man with HTN, chronic renal insufficiency, diverticulosis
• History also includes abdominal aortic aneurysm repair
• Presents with a 2-week history of flank pain wrapping around to abdomen
• Referred by PCP because of abnormal renal CT scan
• Vital signs WNL including afebrile, BP 162/80, HR 65
• Obese male in moderate amount of distress
• Exam benign, including abdominal exam
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MR. SMITH: ABDOMINAL AORTIC ANEURYSM (AAA)
• Elderly + low BP + abdominal pain = AAA• Get the ultrasound – Fast!• Same risk factors as CAD (men>women)• >3 cm defines, >5 cm rupture risk• What diagnosis to consider if simultaneous
rectal bleeding?
Insert ultrasound image of enlarged abdominal aorta
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CASE 6: MS. CONNOR
• 80-year-old woman with HTN, anxiety
• 2-day history of crampy lower abdominal pain; mild n/v/d
• In no apparent distress
• Vital signs WNL other than moderate HTN
• Exam notable for moderate RLQ tenderness without peritonitis
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MS. CONNOR: IMAGING
LearningRadiology.com, retrieved June 1, 2011. Slide 23
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SIGMOID VOLVULUS
• Risk factors: chronic constipation, round worms• More common in males• Abdominal x-ray 65% sensitive• Usually presents with crampy left sided abdominal pain• Often decompressed with sigmoid scope• Can be subtle presentation • Time sensitive diagnosis
Atamanalp SSJ Gastroenterol Hepatol 2007
Emedicine 2008
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CASE 7: MS. LANE
• 79-year-old woman with HTN, diabetes
• Chief complaint: 2 days of n/v/d
• Well-appearing, vital signs WNL
• Seen 48 hours ago for n/v/d: 6 WBC in UA, no nitrate, 4 squamous cells, levofloxacin started
• Patient took 1 tab levofloxacin, had increased vomiting and diarrhea
• Completely benign abdominal exam
• WBC 5,000, chemistries WNL, UA WNL
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MS. LANE: GASTROENTERITIS (I HOPE)
• Observed in ED for 5 hours
• No vomiting or diarrhea; tolerating POs
• D/C with close PCP follow-up
• “You do not always have to be right, you just have to have a contingency plan”
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KEY POINTS
• Acute abdominal pain in the elderly is associated with significant morbidity and mortality
• LFTs often not revealing in acute gallbladder disease
• The diaphragm is not a secure border
• Consider mesenteric ischemia (especially with history of atrial fibrillation, pain out of proportion to exam)
• Elderly + low BP + abdominal pain = AAA(until proven otherwise)
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CASE 1 (1 of 2)
• An 85-year-old woman presents to the ED complaining of 8 hours of abdominal pain. The pain is centered in the epigastrium and she has had no n/v/d.
• She had a normal bowel movement 2 hours before arrival to the ED. She ate a meal last night without difficulty.
• Her past medical history is notable for atrial fibrillation and GERD.
• In the ED she is afebrile with normal vital signs other than mild HTN at 150/95.
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CASE 1 (2 of 2)
• Her exam is notable for a well-appearing elderly woman with mild epigastric tenderness and no peritonitis on exam. She does not have a Murphy’s sign on exam.
• After completing your history and exam, you order labs, including LFTs, CBC, and basic chemistries. Other than a WBC count of 11.7 without a left shift, these labs are all WNL, including the LFTs.
• You now need to decide how you wish to proceed with this patient.
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CASE 1, QUESTION 1
What is the most common etiology of acute abdominal pain presenting to the ED in patients over age 50? Select the one best answer.
A. Biliary tract disease
B. Constipation
C. Nonspecific abdominal pain
D. Urinary tract infection
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CASE 1, QUESTION 2
What is the negative likelihood ratio for all LFTs being normal in assessing whether a patient has acute cholecystitis?
A. 0.1
B. 0.3
C. 0.7
D. 1.0
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CASE 1, QUESTION 3
True or False:
The gallbladder’s visceral innervation originates in the midgut.
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CASE 2 (1 of 2)
• A 67-year-old woman with a medical history of HTN and CAD disease presents to the ED with 3 days of generalized intermittent abdominal pain with n/v/d and some urinary hesitancy.
• She denies black stools or fevers.
• She was seen 2 days ago by her PCP and given phenergan for nausea. She is now presenting to the ED because her pain is not improving.
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CASE 2 (1 of 2)
• On exam she is in significant pain but has only moderate RUQ and RLQ abdominal tenderness.
• She is guaiac-negative on rectal exam and her vitals are notable for a heart rate of 115, BP of 160/100, and temperature of 37.0 C.
• In the ED, her WBC count is 11.5 without a left shift, her UA has 7 WBC without nitrite, squamous cells, or bacteria, and the rest of her labs are normal, including her arterial lactate level of 1.0.
• You now need to decide how to proceed in your evaluation of this patient.
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CASE 2, QUESTION 1
Which of the following is NOT a risk factor for mesenteric ischemia?
A. Advancing age
B. Atrial fibrillation
C. Prior abdominal surgery
D. Recent myocardial infarction
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CASE 2, QUESTION 2
True or False:
Elevated lactate levels are a highly sensitive marker of mesenteric ischemia.
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CASE 2, QUESTION 3
Regarding appendicitis, which of the following classic signs and symptoms do the majority of elderly patients with abdominal pain have? Select the one best answer.
A. Anorexia
B. Migration of pain
C. Pain localized to the RLQ
D. Peritoneal signs on abdominal exam
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ANSWER KEY
• Case 1Question 1: AQuestion 2: CQuestion 3: False
• Case 2Question 1: CQuestion 2: FalseQuestion 3: C
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ACKNOWLEDGMENTSAND DISCLAIMER
• This project was supported by funds from the American Geriatrics Society John A. Hartford Geriatrics for Specialists Grant. This information or content and conclusions are those of the authors and should not be construed as the official position or policy of the American Geriatrics Society or John A. Hartford Foundation, nor should any endorsements be inferred.
• The UNC Center for Aging and Health and UNC Department of Emergency Medicine also provided support for this activity. This work was compiled and edited through the efforts of Jennifer Link, BA.
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THANK YOU FOR YOUR TIME!
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