a systematic approach to hip fracture care and prevention for ......‘hip fracture is all too often...
TRANSCRIPT
Bone Care 2020A systematic approach to hip
fracture care and prevention
for New Zealand
IntroductionOsteoporotic fragility fractures exert a tremendous burden on older New Zealanders, the national economy
and our health and social care system. In 2007, the total cost of osteoporosis was over NZ$1 Billion*, with hip
fracture care alone costing NZ$105 Million. Every day, we spend NZ$325,000 treating fractures and have 312
people in hospitals beds recovering from fractures.
Half of hip fracture sufferers will require long-term care and a quarter will suffer an early death. This burden
will increase rapidly as New Zealand’s 1 million baby boomers retire and age.
Currently, New Zealand has no coordinated, nationwide strategy or systems to manage the increasing number
of older New Zealanders at risk of fragility fractures.
The ProblemInternational research shows that half of hip fracture patients suffer a fragility fracture at another skeletal
site prior to breaking their hip. Nationally representative audits show that people presenting to New Zealand
hospitals with fragility fractures do not receive the globally endorsed standards of secondary preventive care
to reduce future fracture risk.
Response overseas to this issue has been the successful implementation of Fracture Liaison Services (FLS), a
coordinated service where patients presenting with a fragility fracture receive osteoporosis assessment and
treatment where needed, and interventions to reduce falls risk. The outcome of FLS has been a significant
reduction in fracture incidence and associated costs. FLS would ensure equitable access to PHARMAC
subsidised treatments for osteoporosis throughout New Zealand.
While the emphasis in this paper is on post-fracture care for all fragility fracture sufferers, the Australian and
New Zealand Society for Geriatric Medicine has published detailed guidance on best practice for Orthogeriatric
Services, which have been shown to dramatically improve post-hip fracture care. A new National Hip Fracture
Registry, which is in development, will provide an opportunity to benchmark care against professional
standards.
SolutionsOsteoporosis New Zealand proposes to work with the Ministry of Health to develop a national strategy. The
aim is to implement a systematic approach to hip fracture care and prevention.
An important component of that strategy will be the establishment of FLS throughout New Zealand, in addition
to a National Hip Fracture Registry.
BenefitsTo improve quality and consistency of care for all New Zealanders suffering fragility fractures at all skeletal sites.
Fracture Liaison Services and Orthogeriatric Services established by District Health Boards throughout New
Zealand are likely to prevent up to 1,000 cases of hip fracture and save NZ$20 million dollars annually.
Additional savings will be accrued by prevention of fragility fractures at other skeletal sites.
* The Burden of Osteoporosis in New Zealand: 2007-2020. The University of Auckland
2
Executive Summary
The need for a national strategy ..............................................................4
Current standards of care in New Zealand .............................................. 7
The care of hip fracture sufferers ......................................................... 7
The prevention of hip fracture .............................................................8
Systems to deliver best practice ...............................................................9
Orthogeriatric Services .........................................................................9
Fracture Liaison Services .....................................................................9
The Glasgow Fracture Liaison Service, UK ...........................................9
The Kaiser Permanente Healthy Bones Program, USA ........................10
St. Michael’s Hospital Toronto,
Osteoporosis Exemplary Care Program, Canada ................................ 11
Minimal Trauma Fracture Liaison Service,
Concord Repatriation General Hospital Sydney, Australia .................. 11
The Role of Primary Care ....................................................................12
Bone Care 2020: A strategy to improve quality and reduce costs .........13
About Osteoporosis New Zealand ..........................................................15
References ................................................................................................16
3
Table of Contents
A national strategy to implement a systematic approach to hip fracture care and prevention is required because current care is fragmentedHip fractures exert a tremendous burden on older New Zealanders, the national economy and our health and
social care system. During 2007, more than 3,800 people presented to our hospitals with a broken hip at a
total cost of NZ$105 million1. Whilst all osteoporotic fractures are associated with significant pain and loss of
quality of life2, hip fracture sufferers experience the most serious disabilities3. Almost 50% will require long-
term care4 and a quarter will suffer an early death5. Half of hip fracture survivors require help with activities of
daily living6 and during the first year after hip fracture, half of those who walked unaided prior to their fracture
will no longer be able to walk independently7.
‘Hip fracture is all too often the final destination of a 30-year journey fuelled by decreasing bone strength
and increasing falls risk’8
As New Zealand’s 1 million baby boomers9 began to retire in 2011, the impact of osteoporosis on our ageing
population necessitates development of a national strategy with two key aims:
1. To improve the quality and consistency of care for those who break their hip, and
2. To make a determined effort to prevent as many hip fractures as possible
In order to determine how best to devise and implement such a strategy, firstly we need to consider what
happens in the years before people present to hospital with a hip fracture. The various patient experiences
are illustrated in the ‘fragility fracture cycle’ in figure 1. A study based on records from the UK General Practice
Research Database (GPRD)10 reported the lifetime risk of any fracture at age 50 as 53% for women and 21% for
men. Thus, less than one half of women will be fracture free for life. The same study estimated lifetime risks
of fracture by gender at age 50 as:
• Women: Hip 11.4%, Wrist 16.6%, Vertebra 3.1%
• Men: Hip 3.1%, Wrist 2.9%, Vertebra 1.2%
A crucial observation is that fracture begets fracture. Several studies have evaluated future fracture risk
associated with fractures at various skeletal sites. Two major meta-analyses11, 12 found that a prior fracture at
any site is associated with a doubling of future fracture risk. From the obverse perspective, we have known
since the 1980s that half of patients presenting with hip fractures today have experienced prior fragility
fractures in the past13-16.
4
The need for a national strategy
Being able to identify patients that are at high risk of suffering hip fracture in the future is important, but
perhaps a more pressing question is whether we can reduce that fracture risk with intervention. In short, we
can. During the last two decades, a broad range of therapies have been assessed in large-scale randomised
clinical trials which have demonstrated consistent fracture reduction efficacy. The principle agents licensed
for the treatment of osteoporosis throughout the world have been shown to reduce the incidence of fractures
by 30-50%17-28. Fracture reduction efficacy of 50% has been observed for patients with a history of multiple
fractures29. In New Zealand, PHARMAC has approved osteoporosis medicines for the secondary prevention of
fragility fractures30.
Figure 1: The fragility fracture cycle31
Reproduced from the Herald Fractures Report 2010 with permission of the Department of Health in England
Large scale epidemiological studies of older women from Australia and the UK provide us with an indication
of the likely prevalence of fragility fracture i.e. what proportion of older women have already broken a bone
as a result osteoporosis and, usually, a fall?
• Australia: The Australian BoneCare Study32 evaluated 70,000 women aged over 60 years from primary
care physicians’ lists. Twenty nine percent of these women reported a fracture history; 66% reported 1
fracture, 22% reported 2 fractures and 12% reported 3 - 14 fractures.
• United Kingdom: A burden of disease model published in 201133 estimated the number of postmenopausal
women in the UK with osteoporosis and fracture history for the period 2010 to 2021. In 2010, over
1.5 million women were likely to have suffered >1 fracture representing 13% of the postmenopausal
population. Notably, 380,000 of these women had suffered >2 fractures and 96,000 at least 3
fractures.
The ‘pyramid’ in figure 2 allows us to visualise these data and what they mean. A mid-range estimate, taken
from a consensus guideline34, of the proportion of the post-menopausal population that have suffered at least
one fragility fracture is 16%. Given that 50% of hip fracture sufferers have fractured before, from 16% of the
postmenopausal population will emanate 50% of future hip fracture cases35, 36. Individuals who suffer new
fragility fractures will present to medical services, be it hospital emergency departments or community-based
fracture units, and so provide an obvious opportunity for intervention.
A priority for the New Zealand healthcare system should be, in every case, to respond to the first fracture to prevent the second. Unfortunately, as will be discussed in the next section of this paper, the current usual
standard of care for fracture patients in New Zealand is no care.
5
Unrecognised vertebral fragility
fracture
Hip fracture
Secondary hip fracture
Non-hip fragility fracture
Secondary non-hip fragility
fracture
Secondary non-hip fragility
fracture
Fracture Free Recovery
Hip Fracture Free for Life
Fracture Free for Life
Fracture Free at Fifty
Secondary non-hip fragility
fracture
Figure 2. Fracture risk and ease of case-finding: Effective targeting of healthcare resources36
with newfractures
Patients withprior fractures
Patients
Individuals at highfracture risk
Individuals at intermediate
Individuals at low fracture risk
fracture risk6
50% of hip fractures from 16% of the population
50% of hip fractures from 84% of the population
Secondary prevention
Primary prevention
Half of all hip fracture patients give us advance notice that they will present to an orthopaedic trauma unit!
The care of hip fracture sufferersThe need for effective orthopaedic–orthogeriatric co-care of patients admitted to hospital with hip fractures
is well recognised in professional guidance34, 38, 39, including that of the Australian and New Zealand Society
for Geriatric Medicine39. As a consequence, the subspecialty of orthogeriatric medicine is a rapidly growing
professional group throughout the world and is becoming particularly well established in New Zealand40-46.
Several centres have published encouraging reports on rates of post-hip fracture osteoporosis treatment.
However, we currently lack a means to benchmark standards of care across the country.
In late 2011, an Australian and New Zealand Hip Fracture Registry Steering Group (ANZ HFR) was formed by
enthusiasts on both sides of the Tasman, with the express intention of developing Hip Fracture Registries in
New Zealand and throughout Australia47. This effort has been inspired by the establishment of the National
Hip Fracture Database (NHFD) in the UK48. The NHFD has become the largest audit of hip fracture care in the
world. The 2011 NHFD Report described the care of >53,000 people who suffered a hip fracture between April
2010 and March 201149. In total, almost 190,000 cases are currently registered on the NHFD, with >16,000 cases
having been registered in the first quarter of 201250. All hospitals in England, Wales and Northern Ireland are
now registered with NHFD, and 98% of those registered are regularly submitting data. Taken together, this
would suggest that information on the quality of care for almost 90% of hip fractures occurring in the three
Nations served is being captured.
The UK NHFD is a collaborative venture backed by the British Orthopaedic Association and British Geriatrics
Society which has been developed in partnership with other relevant professional organisations and patients’
societies. In a similar spirit, the ANZ HFR has sought engagement with all relevant professional organisations
and patient societies. Osteoporosis New Zealand endorses the ANZ HFR and its aims and objectives, as does
the ANZ Society for Geriatric Medicine, the ANZ Society for Bone and Mineral Research, the ANZ College
of Anaesthetists and the Health Quality and Safety Commission New Zealand, in addition to analogous
organisations in Australia.
During 2012, the ground work to establish a National Hip Fracture Registry in New Zealand is underway and
Osteoporosis New Zealand is committed to working with stakeholder organisations to maximise the impact
of this important initiative. The ANZ HFR newsletter will feature on the Osteoporosis New Zealand website to
update visitors on progress as it occurs.
7
Current standards of care in New Zealand
‘Any condition with
a 1-year mortality
rate approaching
20% and a very
significant morbidity
rate demands that
we make every effort
to reduce the impact
of the condition on
society’37
Professor Geoffrey Horne, Wellington Hospital ‘Hip fracture management - we need to do better’ New Zealand Medical Journal, May 2007
The prevention of hip fractureGiven the scale of the challenge posed by osteoporosis and related fractures, the question for policy makers,
health care professionals and patients, and the organisations representing them, is where to start? In light of
the opportunity presented by secondary fracture prevention discussed previously in this paper, our priority
is very clear:
For the period 2012-2015, Osteoporosis New Zealand will be dedicated to ensuring that every patient presenting to urgent care services in New Zealand with a fragility fracture receives appropriate osteoporosis management and falls assessment to reduce their future fracture riskOur rationale for taking this decision is as follows. National51-62, regional15, 63-69 and local14, 16, 70-97 audits conducted
across the world have shown a secondary fracture prevention care gap to be ubiquitous. In the absence of a
systematic approach to delivery of secondary preventive care, ‘usual care’ is no care. This is particularly acute
for patients presenting with non-hip fragility fractures, described as ‘Herald Fractures’ by the Department of
Health in England31, 98 or ‘Signal Fractures’ by leading investigators in Australia14 for reasons now obvious; half
of hip fracture patients suffer a prior fragility fracture before breaking their hip.
A multi-centre audit evaluated osteoporosis intervention by 8 New Zealand orthopaedic units for patients
admitted to hospital with fragility fractures99, 100. Key findings included:
• 23% of fracture patients were taking some form of osteoporosis treatment on admission; >50% of these
patients were not taking a bisphosphonate
• 77% of patients that were not taking osteoporosis medication on admission
- Of these, <3% had a DXA scan organised in response to their new fracture
• 12% of patients were initiated on treatment, of which the majority was started by a visiting orthogeriatric
service which was available at two of the hospitals; nearly all of these patients were hip fracture
sufferers
• Osteoporosis was mentioned in the discharge summaries for only 30% of the patients that were
already taking osteoporosis treatment, and just 11% of the patients started on medication during their
admission
This study highlighted a near universal secondary prevention care gap for patients with non-hip fragility fractures.
In the absence of an orthogeriatric service, the care gap is extended to hip fracture patients. Establishment of
orthogeriatric services has resulted in dramatic improvements in post-hip fracture osteoporosis treatment at
hospitals in Christchurch42, 44 and Auckland41, 45.
A 2012 publication described secondary prevention rates for patients admitted to Waitemata District Health
Board with a primary or secondary diagnosis of vertebral fracture101. One third of patients were receiving the
optimal combination of treatments advocated in evidence-based guidelines. The authors state that to their
knowledge this study was the first published audit of the secondary prevention of vertebral fractures in New
Zealand.
The current provision of secondary preventive care for patients presenting to New Zealand hospitals with
fragility fractures has been described as follows102:
• Hip fracture patients: Where orthogeriatric services are available, high quality osteoporosis care will be
delivered
• Vertebral fracture patients: Around a third of patients are being managed optimally according to
professional guidance
• Non-hip, non-vertebral fracture patients: Usual care is no care
8
Orthogeriatric ServicesOrthogeriatric Services (OGS) have been established to improve the quality and efficiency of care for patients
presenting with hip fractures. The Australian and New Zealand Society for Geriatric Medicine39 Position
Statement on Orthogeriatric Care provides detailed guidance on best practice throughout the pre-, peri- and
post-operative phases of care for older fracture patients admitted to hospital. A key focus is the concept of
early multidisciplinary coordinated care to reduce in-hospital mortality and medical complications, and to
improve functional outcomes. An integrated approach to post-fracture osteoporosis management and falls
interventions is advocated. As stated previously, delivery of effective orthogeriatric care has been shown to
dramatically improve post-hip fracture rates of osteoporosis treatment at hospitals in Christchurch42, 44 and
Auckland41, 45.
In the UK, the National Hip Fracture Database (NHFD) has provided a means to evaluate the provision of
secondary preventive care for practically all hip fracture sufferers nationally. The NHFD 2011 Report indicated
that 66% of the >53,000 patients evaluated were discharged on bone protection medication and 81% had
received a falls assessment prior to discharge49. In due course, a National Hip Fracture Registry in New
Zealand will be able to provide clinicians, administrators, the Health Quality and Safety Commission, the
Ministry of Health and the Accident Compensation Corporation with accurate data for every hip fracture
sufferer in New Zealand. For transparency amongst all stakeholder groups, crucially including the public, the
UK NHFD presents data in a de-anonymised form i.e. performance at every hospital against professionally
agreed standards of care is in the public domain. Osteoporosis New Zealand would strongly encourage similar
transparency when our ‘NHFR’ becomes operational, as the patients we represent should be informed of the
standards of care provided by their local hospital.
Fracture Liaison ServicesProfessional organisations34, 103-105, patient societies35, 105-107 and policymakers108-115 throughout the world have
recognised the need for systematic approaches to secondary fracture prevention to close the care gap.
Various terms have been used to describe exemplar service models, including ‘Fracture Liaison Services’
in Europe116-125 and Australia126-130, ‘Co-ordinator Programs’ in Canada131-134 and ‘Care Manager Programs’ in the
United States135-137. For the purposes of this paper, we shall use the term Fracture Liaison Service (FLS). The
following four case studies provide an illustration of how FLS operate and what they have achieved in terms
of delivery of secondary preventive care, impact on secondary fracture rates and cost-effectiveness.
The Glasgow Fracture Liaison Service, UK
First developed in 1999, the Glasgow FLS is a system to ensure fracture risk assessment, and treatment
where appropriate, is delivered to all patients with fragility fractures117. The FLS is a ‘doctor light’ service and
is primarily delivered by clinical nurse specialists, who work to pre-agreed protocols to case-find and assess
fracture patients. Consultant Endocrinologists provide medical leadership for the Glasgow FLS. A critical
success factor in development of the Glasgow FLS was establishment of a multi-disciplinary stakeholder
group from project outset, with representation from all relevant hospital specialities, local primary care and
regional health authority and administrative groups.
9
Systems to deliver best practice
Figure 3. The structure of the Glasgow Fracture Liaison Service adapted from The care of patients with fragility
fracture34
* Older patients, where appropriate, are identified and referred for falls assessment
During the first 18 months of operations117:
• More than 4,600 patients with fractures of the hip, wrist, upper arm, ankle, foot, hand and other sites
were seen by Fracture Liaison Nurse Specialists
• Nearly three-quarters were considered for BMD testing and treatment was recommended for
approximately 20% of patients without the need for BMD testing
• 82% of patients tested were found to be osteopenic or osteoporotic at the hip or spine
During the period 2000-2010, 50,000 consecutive fracture patients were assessed by the Glasgow FLS. During
this period, hip fracture rates in Glasgow reduced by 7.3% versus almost a 17% increase in England138, where
only 37% of localities operated an FLS56 by late 2010. A Scottish national audit compared case ascertainment
for hip and wrist fractures in Glasgow versus 5 other centres operating less systematic models of care15. Ninety-
seven percent of hip fracture and 95% of wrist fracture patients were assessed by the Glasgow FLS whereas
less than 30% of fracture patients were assessed by any other service configuration. In May 2011, a formal
cost-effectiveness analysis of the Glasgow FLS was published139. This study concluded that 18 fractures were
prevented, including 11 hip fractures, and £21,000 was saved per 1,000 patients managed by the Glasgow FLS
versus ‘usual care’ in the UK.
The Kaiser Permanente Healthy Bones Program, USA
In the late 1990s, Kaiser Permanente in Southern California resolved to close the secondary fracture prevention
gap for patients presenting to hospital with hip fractures. Subsequently, the program was expanded to include
all older patients presenting with fragility fractures at any site. As time and resources permitted, the Kaiser
team undertook a systematic approach to delivering primary fracture prevention to patients at high risk of
suffering their first fragility fracture. The Healthy Bones Program is underpinned by effective case-finding
made possible by the state-of-the-art HealthConnect® electronic medical record140. The program is primarily
delivered by Care Managers and Nurse Practitioners, who serve as co-ordinators and disease managers.
In 2008, a 37% reduction in the expected hip fracture rate was reported for the population served by the
Kaiser Permanente Southern California system141. This corresponds to the prevention of 935 hip fractures in
the year 2006 (2,510 hip fractures were predicted by actuarial analysis, and 1,575 fractures were actually
observed). The cost of treating a hip fracture was approximately US$33,000. On that basis, it was estimated
that the program saved more than US$30.8 million for Kaiser Permanente Southern California in the 2006.
10
New FracturePresentation
Emergancy Department &
X-Ray
OrthopaedicTrauma
Emergancy Department
OrthopaedicsInpatient
ward
OutpatientsFracture
clinic
Osteoporosistreatment
Fall riskassessment*
Exerciseprogramme
Education programme
Comprehensive communication of management plan to be sup-ported by fully integrated FLS database system
1. FLS identifies fracture patients
2. FLS assessment
St. Michael’s Hospital Toronto, Osteoporosis Exemplary Care Program, Canada
In 2002, the orthopaedic unit at a university teaching hospital in Toronto hired an osteoporosis coordinator to
identify patients with a fragility fracture and to coordinate their education, assessment, referral, and treatment
of underlying osteoporosis131. The Osteoporosis Exemplary Care Program (OECP) provided secondary preventive
care to fracture patients managed in both the in- and out-patient settings.
Four hundred and thirty fracture patients were evaluated during the first year of operations (276 out-patients
and 154 in-patients). Almost all (96%) of these patients received appropriate osteoporosis care:
• 80 out-patients (36%) were treated for osteoporosis prior to assessment by the OECP
• 124 out-patients (56%) were referred to the Metabolic Bone Disease Clinic or to their GP for osteoporosis
treatment
• 31% of the 128 in-patients were treated for osteoporosis prior to assessment by the OECP
• Treatment was initiated for a further 24% of in-patients and another 34% were referred to the Metabolic
Bone Disease Clinic or their GP for post-discharge consultation on osteoporosis treatment
A cost-effectiveness analysis142 of the OECP concluded that a hospital that hired an osteoporosis coordinator
who manages 500 patients with fragility fractures annually could reduce the number of subsequent hip
fractures from 34 to 31 in the first year, with a net hospital cost savings of CN$48,950 (Canadian dollars in
year 2004 values), with use of conservative assumptions. Sensitivity analysis indicated a 90% probability
that hiring a coordinator costs less than CN$25,000 per hip fracture avoided. Hiring a coordinator is a cost-
saving measure even when the coordinator manages as few as 350 patients annually. Greater savings were
anticipated after the first year and when additional costs such as rehabilitation and dependency costs are
considered.
Minimal Trauma Fracture Liaison Service, Concord Repatriation General Hospital Sydney, Australia
The Minimal Trauma Fracture Liaison (MTFL) service128 was established in 2005 at this large tertiary referral
centre in Sydney. The MTFL service provides a good illustration of effective collaboration between a physician-
led FLS and the hospital’s Orthogeriatric Service; the MTFL provides care for non-frail patients with fragility
fractures whilst the Orthogeriatric Service143 focuses on frail patients, including the majority of hip fractures.
The MTFL is delivered by an advanced trainee (i.e. a physician in his/her 4th-6th year of post-graduate
training) which required a 0.4-0.5 FTE appointment.
The impact of the MTFL service was evaluated after 4 years. Fracture patients who chose to decline the
consultation freely offered by the service, in favour of follow-up with their primary care physician, were
considered as a control group for statistical comparison. Refracture incidence for those patients managed by
the MTFL service was 80% lower than the control group.
A recently published cost-effectiveness analysis144 of the MTFL service reported:
• A mean improvement in discounted quality-adjusted life expectancy per patient of 0.089 quality-
adjusted life year gained
• Partial offset of the higher costs of the MTFL service by a decrease in subsequent fractures, which led to
an overall discounted cost increase of AU$1,486 per patient over the 10-year simulation period
• The incremental costs per QALY gained (incremental cost-effectiveness ratio - ICER) were AU$17,291,
which is well below the Australian accepted maximum willingness to pay for one QALY gained of
AU$50,000
Fracture Liaison Services improve the quality of secondary preventive care which will reduce costs through
a reduction in unscheduled emergency admissions for fragility fractures. Every District Health Board in New
Zealand should undertake an audit of current standards of secondary preventive care. In response to the
findings of those audits, FLS should be established to close existing care gaps.
11
The Role of Primary CareManagement of long-term conditions is the forte of the primary care team. Osteoporosis is a chronic disease
which afflicts sufferers over many decades, during which ‘acute exacerbations’ will come to clinical attention in
the form of fragility fractures34. As such, General Practitioners are crucial to delivery of long-term management
plans to reduce fracture risk. GPs have transformed the secondary preventive care of patients experiencing
myocardial infarctions, and are equally well placed to do the same for patients with fragility fractures.
In localities lacking Fracture Liaison Services, the majority of patients that have suffered fragility fractures
in the past will not have received secondary preventive care. GPs in Australia32, 145 and the UK146, 147 have
participated in large scale programs to evaluate osteoporosis assessment and treatment rates for patients
with a history of fragility fracture. Alarmingly low rates were identified by both groups; however, one UK group
transformed the quality of care146. The new service model was delivered by a team comprised primarily of an
osteoporosis nurse specialist reporting to a general practitioner with a specialist interest in osteoporosis. Prior
to implementation of the programme, 9% of fragility fracture patients were managed according to national
guidelines, which increased to 64% afterwards.
In March 2012, the journal of the Royal Australian College of General Practitioners, Australian Family Physician,
was devoted to bone related matters and osteoporosis in particular. An editorial comment highlighted the
ubiquitous nature of the secondary fracture prevention care gap148:
‘An area of clarity around what we should do is secondary prevention after the first fracture, but here
reality is often not the ideal. In part it is systems issues, in part human. Even if osteoporosis is detected
and treated, there are very high rates of discontinuation of treatment – two-thirds discontinue treatment
within 12 months.
While drug related side effects and dosing regimens might be addressed, I suggest there must be a more
fundamental problem with the value our health system believes treatment offers and the value that the
individual recipient believes it offers them.’
In response to this, colleagues from Osteoporosis Australia and the Royal College of General Practitioners in
the UK shared experience of new measures to improve secondary fracture prevention in UK general practice149.
From 1st April 2012, a component of UK GPs’ performance-related pay will be dependent upon creation of
fragility fracture registries in GP practices and demonstration that patients are being treated for osteoporosis
in accordance with national guidelines150. To support UK GPs to deliver these new standards of care, the Royal
College of General Practitioners and the UK National Osteoporosis Society developed a web-based resource
- http://www.osteoporosis-resources.org.uk/. Osteoporosis New Zealand intends to explore opportunities for
similar collaborative ventures with the Royal New Zealand College of General Practitioners.
12
fracturepatients
fracture patients
Non-hip fragility
Older people
Hip
other injurious falls
of 1st fragility fracture or
Individuals at high risk
The strategy for implementation of a systematic approach to hip fracture care and prevention in New Zealand
is depicted in the ‘pyramid’ in figure 4. High quality care of hip fracture patients is less expensive than the
alternative34. In England, the Department of Health has recognised this by introduction of a financial incentive
linked to delivery of professionally agreed standards of care151, 152. The initial interest in the ANZ Hip Fracture
Registry initiative suggests a similar appetite for change exists in New Zealand47, with all relevant stakeholder
organisations keen to endorse development of a National Hip Fracture Registry. Osteoporosis New Zealand
is committed to work with all stakeholders to develop this tool that will enable benchmarking of care across
the country.
Figure 4. A systematic approach to hip fracture care and prevention for
New Zealand for 2012-2020
Adapted from Falls and Fractures: Effective interventions in Health and Social Care. Department of Health 2009110
13
Bone Care 2020: A strategy to improve quality
and reduce costs
Objective 1: Improve outcomes and quality
of care after hip fractures by delivering ANZ
professional standards of care monitored by a
new NZ National Hip Fracture Registry
Objective 2: Respond to the first fracture to prevent the second through universal access
to Fracture Liaison Services in every District
Health Board in New Zealand
Objective 3: GPs to stratify fracture risk
within their practice population using fracture
risk assessment tools supported by local
access to axial bone densitometry
Objective 4: Consistent delivery of public health messages on preserving physical
activity, healthy lifestyles and reducing
environmental hazards
Maximise cost-effectiveness by stepwise delivery
Secondary fracture prevention provides a major opportunity to rapidly reduce the incidence of hip fractures in New Zealand.
In order to close current and historical care gaps in the provision of post-fracture care, during the period 2012
– 2015 we need:
• A Fracture Liaison Service in every hospital/DHB to case find all new fragility fracture patients
• A systematic approach to case-finding the last 5 years’ fracture patients in every GP practice in NZ
• To drive public awareness that fracture begets fracture and that effective, safe treatments to prevent
fractures are available as daily or weekly pills, or daily or annual injections
In order to establish this new national standard of care for fragility fracture prevention:
• Osteoporosis New Zealand invites all relevant professional organisations, policy groups and private sector partners to join a National Fragility Fracture Alliance to develop and implement this strategy for all older New Zealanders
• Osteoporosis New Zealand invites the Ministry of Health to work collaboratively towards new Ministerial Targets for hip fracture care and prevention
• Osteoporosis New Zealand invites the Royal New Zealand College of General Practitioners to collaboratively develop clinically and cost-effective programs for primary fracture prevention
During the period 2012-2015, the focus of efforts to implement the national strategy will be upon secondary
fracture prevention. Closure of the current care gap is achievable nationwide by 2015. The focus of the period
2016-2020 will be to systematically identify patients at high risk of suffering their first fragility fracture in
general, and hip fracture in particular, in a cost-effective way.
Comprehensive implementation of a secondary fracture prevention strategy has the potential to reduce the
incidence of hip fracture by 20-25% versus the expected rate153. That would equate to up to 1,000 older New
Zealanders every year avoiding a hip fracture, with a potential cost reduction of NZ$20 million per year1.
Additional savings will be accrued by prevention of fragility fractures at other skeletal sites. Subsequent
implementation of structured primary prevention programmes could result in up to 50% of fractures being
prevented135, 141. Given that half of hip fracture patients give us advance notice that they will break their hip
in the future, older people and the country are currently paying far too high a price for the status quo to
persist.
‘Whether at the level of a local general hospital or a national healthcare system, successful transformation of care relies upon consensus being achieved amongst all the players in the multi-disciplinary team who care for fracture patients.
As many millions of patients present to hospitals worldwide with fragility fractures every year, the opportunity to improve outcomes is too good to miss.’35
14
Osteoporosis New Zealand is the only national organisation in New Zealand dedicated to improving care
and outcomes for osteoporosis sufferers. The focus of Osteoporosis New Zealand activities for the period
2012-2015 is upon closing the current care gap for patients that have suffered fragility fractures. In October
2012, Osteoporosis New Zealand published Bone Care 2020: A systematic approach to hip fracture care
and prevention for New Zealand. We invite all relevant professional organisations, policy groups and private
sector partners to join a National Fragility Fracture Alliance to implement this strategy for all older New
Zealanders.
Web: www.bones.org.nz
Email: [email protected] 15
About Osteoporosis New Zealand
1. Brown P, McNeill R, Leung W, Radwan E, Willingale J. Current and future economic burden of osteoporosis
in New Zealand. Appl Health Econ Health Policy. Mar 1 2011;9(2):111-123.
2. Rabenda V, Manette C, Lemmens R, Mariani AM, Struvay N, Reginster JY. Prevalence and impact of
osteoarthritis and osteoporosis on health-related quality of life among active subjects. Aging Clin Exp Res.
Feb 2007;19(1):55-60.
3. Pasco JA, Sanders KM, Hoekstra FM, Henry MJ, Nicholson GC, Kotowicz MA. The human cost of fracture.
Osteoporos Int. Dec 2005;16(12):2046-2052.
4. Access Economics. The Burden of Brittle Bones: Costing Osteoporosis in Australia. Canberra 2001.
5. Kanis JA, Oden A, Johnell O, De Laet C, Jonsson B, Oglesby AK. The components of excess mortality after
hip fracture. Bone. May 2003;32(5):468-473.
6. Scaf-Klomp W, van Sonderen E, Sanderman R, Ormel J, Kempen GI. Recovery of physical function after
limb injuries in independent older people living at home. Age Ageing. May 2001;30(3):213-219.
7. Osnes EK, Lofthus CM, Meyer HE, et al. Consequences of hip fracture on activities of daily life and
residential needs. Osteoporos Int. Jul 2004;15(7):567-574.
8. Mitchell PJ. Fracture Liaison Services: A systematic approach to secondary fracture prevention.
Osteoporosis Review 2009;17(1):14-16.
9. Cleaver M, Green BC, Muller TE. Using consumer behaviour research to understand the baby boomer
tourist. Journal of Hospitality & Tourism Research. 2000;24(2):274-287.
10. van Staa TP, Dennison EM, Leufkens HGM, Cooper C. Epidemiology of fractures in England and Wales.
Bone. 2001;29(6):517-522.
11. Klotzbuecher CM, Ross PD, Landsman PB, Abbott TA, 3rd, Berger M. Patients with prior fractures have an
increased risk of future fractures: a summary of the literature and statistical synthesis. J Bone Miner Res.
Apr 2000;15(4):721-739.
12. Kanis JA, Johnell O, De Laet C, et al. A meta-analysis of previous fracture and subsequent fracture risk.
Bone. Aug 2004;35(2):375-382.
13. Gallagher JC, Melton LJ, Riggs BL, Bergstrath E. Epidemiology of fractures of the proximal femur in
Rochester, Minnesota. Clin Orthop Relat Res. Jul-Aug 1980(150):163-171.
14. Port L, Center J, Briffa NK, Nguyen T, Cumming R, Eisman J. Osteoporotic fracture: missed opportunity for
intervention. Osteoporos Int. Sep 2003;14(9):780-784.
15. McLellan A, Reid D, Forbes K, et al. Effectiveness of Strategies for the Secondary Prevention of Osteoporotic
Fractures in Scotland (CEPS 99/03): NHS Quality Improvement Scotland; 2004.
16. Edwards BJ, Bunta AD, Simonelli C, Bolander M, Fitzpatrick LA. Prior fractures are common in patients
with subsequent hip fractures. Clin Orthop Relat Res. Aug 2007;461:226-230.
17. Black DM, Cummings SR, Karpf DB, et al. Randomised trial of effect of alendronate on risk of fracture
in women with existing vertebral fractures. Fracture Intervention Trial Research Group. Lancet. Dec 7
1996;348(9041):1535-1541.
18. Black DM, Delmas PD, Eastell R, et al. Once-yearly zoledronic acid for treatment of postmenopausal
osteoporosis. N Engl J Med. May 3 2007;356(18):1809-1822.
16
References
19. Chesnut IC, Skag A, Christiansen C, et al. Effects of oral ibandronate administered daily or intermittently
on fracture risk in postmenopausal osteoporosis. J Bone Miner Res. Aug 2004;19(8):1241-1249.
20. Cummings SR, Black DM, Thompson DE, et al. Effect of alendronate on risk of fracture in women with
low bone density but without vertebral fractures: results from the Fracture Intervention Trial. JAMA. Dec
23-30 1998;280(24):2077-2082.
21. Cummings SR, San Martin J, McClung MR, et al. Denosumab for prevention of fractures in postmenopausal
women with osteoporosis. N Engl J Med. Aug 20 2009;361(8):756-765.
22. Ettinger B, Black DM, Mitlak BH, et al. Reduction of vertebral fracture risk in postmenopausal women with
osteoporosis treated with raloxifene: results from a 3-year randomized clinical trial. Multiple Outcomes of
Raloxifene Evaluation (MORE) Investigators. JAMA. Aug 18 1999;282(7):637-645.
23. Harris ST, Watts NB, Genant HK, et al. Effects of risedronate treatment on vertebral and nonvertebral
fractures in women with postmenopausal osteoporosis: a randomized controlled trial. Vertebral Efficacy
With Risedronate Therapy (VERT) Study Group. JAMA. Oct 13 1999;282(14):1344-1352.
24. Lyles KW, Colon-Emeric CS, Magaziner JS, et al. Zoledronic Acid in Reducing Clinical Fracture and Mortality
after Hip Fracture. N Engl J Med. 2007;357:nihpa40967.
25. McClung MR, Geusens P, Miller PD, et al. Effect of risedronate on the risk of hip fracture in elderly women.
Hip Intervention Program Study Group. N Engl J Med. Feb 1 2001;344(5):333-340.
26. Neer RM, Arnaud CD, Zanchetta JR, et al. Effect of parathyroid hormone (1-34) on fractures and bone
mineral density in postmenopausal women with osteoporosis. N Engl J Med. May 10 2001;344(19):1434-
1441.
27. Reginster J, Minne HW, Sorensen OH, et al. Randomized trial of the effects of risedronate on vertebral
fractures in women with established postmenopausal osteoporosis. Vertebral Efficacy with Risedronate
Therapy (VERT) Study Group. Osteoporos Int. 2000;11(1):83-91.
28. Reginster JY, Seeman E, De Vernejoul MC, et al. Strontium ranelate reduces the risk of nonvertebral
fractures in postmenopausal women with osteoporosis: Treatment of Peripheral Osteoporosis (TROPOS)
study. J Clin Endocrinol Metab. May 2005;90(5):2816-2822.
29. Ensrud KE, Black DM, Palermo L, et al. Treatment with alendronate prevents fractures in women at
highest risk: results from the Fracture Intervention Trial. Arch Intern Med. Dec 8-22 1997;157(22):2617-
2624.
30. PHARMAC. Pharmaceutical schedule. Wellington: Pharmaceutical Management Agency; 2012.
31. Department of Health. Herald Fractures: Clinical burden of disease and financial impact. 2010.
32. Eisman J, Clapham S, Kehoe L, Australian BoneCare S. Osteoporosis prevalence and levels of treatment
in primary care: the Australian BoneCare Study. J Bone Miner Res. Dec 2004;19(12):1969-1975.
33. Gauthier A, Kanis JA, Jiang Y, et al. Epidemiological burden of postmenopausal osteoporosis in the UK
from 2010 to 2021: estimations from a disease model. Arch Osteoporos. 2011;6(1-2):179-188.
34. British Orthopaedic Association, British Geriatrics Society. The care of patients with fragility fracture
2007.
35. Marsh D, Akesson K, Beaton DE, et al. Coordinator-based systems for secondary prevention in fragility
fracture patients. Osteoporos Int. Jul 2011;22(7):2051-2065.
36. Mitchell PJ. Fracture Liaison Services: the UK experience. Osteoporos Int. Aug 2011;22 Suppl 3:487-494.
37. Horne G. Hip fracture management in New Zealand--we need to do better. N Z Med J.
2007;120(1254):U2531.
38. Kates SL, Mears SC, Sieber F, et al. A Guide to Improving the Care of Patients with Fragility Fractures.
Geriatric Orthopaedic Surgery & Rehabilitation. 2011;2(1):5-37.
39. Mak J, Wong E, Cameron I, Australian, New Zealand Society for Geriatric M. Australian and New
Zealand Society for Geriatric Medicine. Position statement--orthogeriatric care. Australas J Ageing. Sep
2011;30(3):162-169.
40. Tha HS, Armstrong D, Broad J, Paul S, Wood P. Hip fracture in Auckland: contrasting models of care in two
major hospitals. Intern Med J. Feb 2009;39(2):89-94.
41. Kenealy H, Paul S, Walker K, Garg A. Secondary prophylaxis of osteoporotic fractures in an orthogeriatric
service. Australas J Ageing. Mar 2011;30(1):41.
17
42. Thwaites J, Mann F, Gilchrist N, McKie J, Sainsbury R. Older patients with hip fractures: evaluation of a
long-term specialist orthopaedic medicine service in their outcomes. N Z Med J. 2007;120(1254):U2535.
43. Thwaites JH, Mann F, Gilchrist N, Frampton C, Rothwell A, Sainsbury R. Shared care between geriatricians
and orthopaedic surgeons as a model of care for older patients with hip fractures. N Z Med J. May 6
2005;118(1214):U1438.
44. Sidwell AI, Wilkinson TJ, Hanger HC. Secondary prevention of fractures in older people: evaluation of a
protocol for the investigation and treatment of osteoporosis. Intern Med J. Mar 2004;34(3):129-132.
45. Fergus L, Cutfield G, Harris R. Auckland City Hospital’s ortho-geriatric service: an audit of patients aged
over 65 with fractured neck of femur. N Z Med J. Jun 24 2011;124(1337):40-54.
46. Davidson CW, Merrilees MJ, Wilkinson TJ, McKie JS, Gilchrist NL. Hip fracture mortality and morbidity--
can we do better? N Z Med J. Jul 27 2001;114(1136):329-332.
47. Australian and New Zealand Hip Fracture Registry Steering Group. Towards a National Hip Fracture
Registry: Enhancing Outcomes for Older People. Vol 1. Sydney; 2012:1-2.
48. British Orthopaedic Association, British Geriatrics Society, Healthcare Quality Improvement Partnership.
The National Hip Fracture Database. http://www.nhfd.co.uk/. Accessed 21-07-2011.
49. British Orthopaedic Association, British Geriatrics Society, Healthcare Quality Improvement Partnership.
The National Hip Fracture Database: National Report 2011. 2011.
50. Plant F. Personal communication on latest data from the UK National Hip Fracture Database. In: Mitchell
PJ, ed; 2012.
51. Teede HJ, Jayasuriya IA, Gilfillan CP. Fracture prevention strategies in patients presenting to Australian
hospitals with minimal-trauma fractures: a major treatment gap. Intern Med J. Oct 2007;37(10):674-679.
52. Papaioannou A, Kennedy CC, Ioannidis G, et al. The osteoporosis care gap in men with fragility fractures:
the Canadian Multicentre Osteoporosis Study. Osteoporos Int. Apr 2008;19(4):581-587.
53. Smektala R, Endres HG, Dasch B, Bonnaire F, Trampisch HJ, Pientka L. Quality of care after distal radius
fracture in Germany. Results of a fracture register of 1,201 elderly patients. Unfallchirurg. Jan 2009;112(1):46-
54.
54. Suhm N, Lamy O, Lippuner K, OsteoCare study g. Management of fragility fractures in Switzerland: results
of a nationwide survey. Swiss Med Wkly. Nov 15 2008;138(45-46):674-683.
55. Panneman MJ, Lips P, Sen SS, Herings RM. Undertreatment with anti-osteoporotic drugs after hospitalization
for fracture. Osteoporos Int. Feb 2004;15(2):120-124.
56. Royal College of Physicians’ Clinical Effectiveness and Evaluation Unit. Falling standards, broken promises:
Report of the national audit of falls and bone health in older people 2010. 2011.
57. Gehlbach SH, Avrunin JS, Puleo E, Spaeth R. Fracture risk and antiresorptive medication use in older
women in the USA. Osteoporos Int. Jun 2007;18(6):805-810.
58. Jennings LA, Auerbach AD, Maselli J, Pekow PS, Lindenauer PK, Lee SJ. Missed opportunities for
osteoporosis treatment in patients hospitalized for hip fracture. J Am Geriatr Soc. Apr 2010;58(4):650-
657.
59. Chakravarthy J, Ali A, Iyengar S, Porter K. Secondary prevention of fragility fractures by orthopaedic teams
in the UK: a national survey. Int J Clin Pract. Mar 2008;62(3):382-387.
60. Tosi LL, Gliklich R, Kannan K, Koval KJ. The American Orthopaedic Association’s “own the bone” initiative
to prevent secondary fractures. J Bone Joint Surg Am. Jan 2008;90(1):163-173.
61. Kurup HV, Andrew JG. Secondary prevention of osteoporosis after Colles fracture: Current practice. Joint
Bone Spine. Jan 2008;75(1):50-52.
62. Carnevale V, Nieddu L, Romagnoli E, et al. Osteoporosis intervention in ambulatory patients with previous
hip fracture: a multicentric, nationwide Italian survey. Osteoporos Int. 2006;17(3):478-483.
63. Hajcsar EE, Hawker G, Bogoch ER. Investigation and treatment of osteoporosis in patients with fragility
fractures. CMAJ. Oct 3 2000;163(7):819-822.
64. Bessette L, Ste-Marie LG, Jean S, et al. The care gap in diagnosis and treatment of women with a fragility
fracture. Osteoporos Int. Jan 2008;19(1):79-86.
65. Metge CJ, Leslie WD, Manness LJ, et al. Postfracture care for older women: gaps between optimal care and
actual care. Can Fam Physician. Sep 2008;54(9):1270-1276.
18
66. All Wales Osteoporosis Advisory Group. All Wales Audit of Secondary Prevention of Osteoporotic Fractures
2009. Aberystwyth 2009.
67. Solomon DH, Finkelstein JS, Katz JN, Mogun H, Avorn J. Underuse of osteoporosis medications in elderly
patients with fractures. Am J Med. Oct 1 2003;115(5):398-400.
68. Andrade SE, Majumdar SR, Chan KA, et al. Low frequency of treatment of osteoporosis among
postmenopausal women following a fracture. Arch Intern Med. Sep 22 2003;163(17):2052-2057.
69. Beringer TR, Finch M, Mc ATH, et al. A study of bone mineral density in women with forearm fracture in
Northern Ireland. Osteoporos Int. Apr 2005;16(4):430-434.
70. Lofman O, Hallberg I, Berglund K, et al. Women with low-energy fracture should be investigated for
osteoporosis. Acta Orthop. Dec 2007;78(6):813-821.
71. Nixon MF, Ibrahim T, Johari Y, Eltayef S, Hariharan D, Taylor GJ. Managing osteoporosis in patients with
fragility fractures: did the British Orthopaedic Association guidelines have any impact? Ann R Coll Surg
Engl. Jul 2007;89(5):504-509.
72. Prasad N, Sunderamoorthy D, Martin J, Murray JM. Secondary prevention of fragility fractures: are we
following the guidelines? Closing the audit loop. Ann R Coll Surg Engl. Sep 2006;88(5):470-474.
73. Gidwani S, Davidson N, Trigkilidas D, Blick C, Harborne R, Maurice HD. The detection of patients with
‘fragility fractures’ in fracture clinic - an audit of practice with reference to recent British Orthopaedic
Association guidelines. Ann R Coll Surg Engl. Mar 2007;89(2):147-150.
74. Javid KS, Thien A, Hill R. Implementation of and compliance with NICE guidelines in the secondary
prevention of osteoporotic fractures in postmenopausal women. Ann R Coll Surg Engl. Apr 2008;90(3):213-
215.
75. Formiga F, Rivera A, Nolla JM, Coscujuela A, Sole A, Pujol R. Failure to treat osteoporosis and the risk of
subsequent fractures in elderly patients with previous hip fracture: a five-year retrospective study. Aging
Clin Exp Res. Apr 2005;17(2):96-99.
76. Luthje P, Nurmi-Luthje I, Kaukonen JP, Kuurne S, Naboulsi H, Kataja M. Undertreatment of osteoporosis
following hip fracture in the elderly. Arch Gerontol Geriatr. Jul-Aug 2009;49(1):153-157.
77. Khan SA, de Geus C, Holroyd B, Russell AS. Osteoporosis follow-up after wrist fractures following minor
trauma. Arch Intern Med. May 28 2001;161(10):1309-1312.
78. Cuddihy MT, Gabriel SE, Crowson CS, et al. Osteoporosis intervention following distal forearm fractures:
a missed opportunity? Arch Intern Med. Feb 25 2002;162(4):421-426.
79. Kiebzak GM, Beinart GA, Perser K, Ambrose CG, Siff SJ, Heggeness MH. Undertreatment of osteoporosis
in men with hip fracture. Arch Intern Med. Oct 28 2002;162(19):2217-2222.
80. Feldstein A, Elmer PJ, Orwoll E, Herson M, Hillier T. Bone mineral density measurement and treatment
for osteoporosis in older individuals with fractures: a gap in evidence-based practice guideline
implementation. Arch Intern Med. Oct 13 2003;163(18):2165-2172.
81. Fortes EM, Raffaelli MP, Bracco OL, et al. [High morbid-mortability and reduced level of osteoporosis
diagnosis among elderly people who had hip fractures in Sao Paulo City]. Arq Bras Endocrinol Metabol.
Oct 2008;52(7):1106-1114.
82. Kimber CM, Grimmer-Somers KA. Evaluation of current practice: compliance with osteoporosis clinical
guidelines in an outpatient fracture clinic. Aust Health Rev. Feb 2008;32(1):34-43.
83. Aboyoussef M, Vierkoetter KR. Underdiagnosis and under-treatment of osteoporosis following fragility
fracture. Hawaii Med J. Jul 2007;66(7):185-187.
84. Seagger R, Howell J, David H, Gregg-Smith S. Prevention of secondary osteoporotic fractures--why are we
ignoring the evidence? Injury. Oct 2004;35(10):986-988.
85. Talbot JC, Elener C, Praveen P, Shaw DL. Secondary prevention of osteoporosis: Calcium, Vitamin D and
bisphosphonate prescribing following distal radial fracture. Injury. Nov 2007;38(11):1236-1240.
86. Wong PK, Spencer DG, McElduff P, Manolios N, Larcos G, Howe GB. Secondary screening for osteoporosis
in patients admitted with minimal-trauma fracture to a major teaching hospital. Intern Med J. Nov
2003;33(11):505-510.
87. Inderjeeth CA, Glennon D, Petta A. Study of osteoporosis awareness, investigation and treatment of
patients discharged from a tertiary public teaching hospital. Intern Med J. Sep 2006;36(9):547-551.
88. Kamel HK. Secondary prevention of hip fractures among the hospitalized elderly: are we doing enough?
J Clin Rheumatol. Apr 2005;11(2):68-71.
19
89. Cadarette SM, Katz JN, Brookhart MA, et al. Trends in drug prescribing for osteoporosis after hip fracture,
1995-2004. J Rheumatol. Feb 2008;35(2):319-326.
90. Feldstein AC, Nichols GA, Elmer PJ, Smith DH, Aickin M, Herson M. Older women with fractures: patients
falling through the cracks of guideline-recommended osteoporosis screening and treatment. J Bone Joint
Surg Am. Dec 2003;85-A(12):2294-2302.
91. Kelly AM, Clooney M, Kerr D, Ebeling PR. When continuity of care breaks down: a systems failure in
identification of osteoporosis risk in older patients treated for minimal trauma fractures. Med J Aust. Apr
7 2008;188(7):389-391.
92. Castel H, Bonneh DY, Sherf M, Liel Y. Awareness of osteoporosis and compliance with management
guidelines in patients with newly diagnosed low-impact fractures. Osteoporos Int. 2001;12(7):559-564.
93. Bahl S, Coates PS, Greenspan SL. The management of osteoporosis following hip fracture: have we
improved our care? Osteoporos Int. Nov 2003;14(11):884-888.
94. Hooven F, Gehlbach SH, Pekow P, Bertone E, Benjamin E. Follow-up treatment for osteoporosis after
fracture. Osteoporos Int. Mar 2005;16(3):296-301.
95. Peng EW, Elnikety S, Hatrick NC. Preventing fragility hip fracture in high risk groups: an opportunity
missed. Postgrad Med J. Aug 2006;82(970):528-531.
96. Malochet-Guinamand S, Chalard N, Billault C, Breuil N, Ristori JM, Schmidt J. Osteoporosis treatment in
postmenopausal women after peripheral fractures: impact of information to general practitioners. Joint
Bone Spine. Dec 2005;72(6):562-566.
97. Briancon D, de Gaudemar JB, Forestier R. Management of osteoporosis in women with peripheral
osteoporotic fractures after 50 years of age: a study of practices. Joint Bone Spine. Mar 2004;71(2):128-
130.
98. Oliver D. Development of services for older patients with falls and fractures in England: successes,
failures, lessons and controversies. Arch Gerontol Geriatr. Dec 2009;49 Suppl 2:S7-12.
99. Stracey-Clitherow H, Bossley C. Osteoporosis intervention by New Zealand orthopaedic units: A multi-
centre audit. J Bone Joint Surg Br. 2009;91-B(SUPP II):342.
100. Stracey-Clitherow HD, Bossley CJ. Osteoporosis Intervention by New Zealand Orthopaedic Departments
in Patients with Fragility Fractures: A multi-centre audit. Wellington 2009.
101. Bloomfield K, Singh J. Secondary prevention of vertebral fractures in a large New Zealand District Health
Board. N Z Med J. Nov 4 2011;124(1345):26-33.
102. Mitchell PJ. Fracture Liaison Service Resource Pack. Novartis. 2012.
103. Dreinhofer KE, Feron JM, Herrera A, et al. Orthopaedic surgeons and fragility fractures. A survey by
the Bone and Joint Decade and the International Osteoporosis Foundation. J Bone Joint Surg Br. Sep
2004;86(7):958-961.
104. International Society for Fracture Repair. Osteoporotic Fracture Campaign. http://www.fractures.com/
about_ofc.html. Accessed 28-10-2011.
105. National Bone Health Alliance. Eye on bone health: Secondary fracture prevention initiative. Vol 1.
Washington DC; 2011:1.
106. National Osteoporosis Society. Protecting fragile bones: A strategy to reduce the impact of osteoporosis
and fragility fractures in England/Scotland/Wales/Northern Ireland May-Jun 2009 2009.
107. Osteoporosis Canada. Osteoporosis: Towards a fracture free future. Toronto 2011.
108. Office of the Surgeon General. Bone Health and Osteoporosis: A Report of the Surgeon General. In: US
Department of Health and Human Services, ed. Washington; 2004.
109. Department of Health. Fracture prevention services: an economic evaluation.; 2009.
110. Department of Health. Falls and fractures: Effective interventions in health and social care. In: Department
of Health, ed; 2009.
111. Australian Government. National service improvement framework for osteoarthritis, rheumatoid arthritis
and osteoporosis. In: Department of Health and Ageing, ed. Canberra; 2005.
112. NSW Government Health. NSW Model of Care for Osteoporotic Refracture Prevention. In: NSW Agency for
Clinical Innovation Musculoskeletal Network, ed. Chatswood; 2011.
20
113. Statewide Orthopaedic Clinical Network and Rehabilitation Clinical Network. Models of Care for
Orthopaedic Rehabilitation - Fragility Fractures General Orthopaedic Trauma and Arthroplasty. In:
Government of South Australia, SA Health, eds. Adelaide; 2011.
114. Government of Western Australia. Osteoporosis Model of Care. In: Department of Health Musculoskeletal
Diabetes & Endocrine Falls Prevention and Aged Care Health Networks (WA), ed. Perth; 2011.
115. Ministry of Health and Long-term Care, Ontario Women’s Health Council, Osteoporosis Canada. Ontario
Osteoporosis Strategy. http://www.osteostrategy.on.ca/. Accessed 9 February, 2012.
116. Clunie G, Stephenson S. Implementing and running a fracture liaison service: An integrated clinical
service providing a comprehensive bone health assessment at the point of fracture management. Journal
of Orthopaedic Nursing. 2008;12:156-162.
117. McLellan AR, Gallacher SJ, Fraser M, McQuillian C. The fracture liaison service: success of a program for the
evaluation and management of patients with osteoporotic fracture. Osteoporos Int. Dec 2003;14(12):1028-
1034.
118. Premaor MO, Pilbrow L, Tonkin C, Adams M, Parker RA, Compston J. Low rates of treatment in
postmenopausal women with a history of low trauma fractures: results of audit in a Fracture Liaison
Service. QJM. Jan 2010;103(1):33-40.
119. Wright SA, McNally C, Beringer T, Marsh D, Finch MB. Osteoporosis fracture liaison experience: the Belfast
experience. Rheumatol Int. Aug 2005;25(6):489-490.
120. Blonk MC, Erdtsieck RJ, Wernekinck MG, Schoon EJ. The fracture and osteoporosis clinic: 1-year results
and 3-month compliance. Bone. Jun 2007;40(6):1643-1649.
121. Huntjens KM, van Geel TC, Geusens PP, et al. Impact of guideline implementation by a fracture nurse
on subsequent fractures and mortality in patients presenting with non-vertebral fractures. Injury. Sep
2011;42 Suppl 4:S39-43.
122. van Helden S, Cauberg E, Geusens P, Winkes B, van der Weijden T, Brink P. The fracture and osteoporosis
outpatient clinic: an effective strategy for improving implementation of an osteoporosis guideline. J Eval
Clin Pract. Oct 2007;13(5):801-805.
123. Astrand J, Thorngren KG, Tagil M, Akesson K. 3-year follow-up of 215 fracture patients from a prospective
and consecutive osteoporosis screening program. Fracture patients care! Acta Orthop. Jun 2008;79(3):404-
409.
124. Carpintero P, Gil-Garay E, Hernandez-Vaquero D, Ferrer H, Munuera L. Interventions to improve inpatient
osteoporosis management following first osteoporotic fracture: the PREVENT project. Arch Orthop Trauma
Surg. Feb 2009;129(2):245-250.
125. Huntjens KM, van Geel TA, Blonk MC, et al. Implementation of osteoporosis guidelines: a survey of five
large fracture liaison services in the Netherlands. Osteoporos Int. Jul 2011;22(7):2129-2135.
126. Giles M, Van Der Kallen J, Parker V, et al. A team approach: implementing a model of care for preventing
osteoporosis related fractures. Osteoporos Int. Aug 2011;22(8):2321-2328.
127. Kuo I, Ong C, Simmons L, Bliuc D, Eisman J, Center J. Successful direct intervention for osteoporosis in
patients with minimal trauma fractures. Osteoporos Int. Dec 2007;18(12):1633-1639.
128. Lih A, Nandapalan H, Kim M, et al. Targeted intervention reduces refracture rates in patients with
incident non-vertebral osteoporotic fractures: a 4-year prospective controlled study. Osteoporos Int. Mar
2011;22(3):849-858.
129. Vaile J, Sullivan L, Bennett C, Bleasel J. First Fracture Project: addressing the osteoporosis care gap. Intern
Med J. Oct 2007;37(10):717-720.
130. Inderjeeth CA, Glennon DA, Poland KE, et al. A multimodal intervention to improve fragility fracture
management in patients presenting to emergency departments. Med J Aust. Aug 2 2010;193(3):149-153.
131. Bogoch ER, Elliot-Gibson V, Beaton DE, Jamal SA, Josse RG, Murray TM. Effective initiation of osteoporosis
diagnosis and treatment for patients with a fragility fracture in an orthopaedic environment. J Bone Joint
Surg Am. Jan 2006;88(1):25-34.
132. Majumdar SR, Beaupre LA, Harley CH, et al. Use of a case manager to improve osteoporosis treatment
after hip fracture: results of a randomized controlled trial. Arch Intern Med. Oct 22 2007;167(19):2110-
2115.
133. Majumdar SR, Johnson JA, Bellerose D, et al. Nurse case-manager vs multifaceted intervention to improve
quality of osteoporosis care after wrist fracture: randomized controlled pilot study. Osteoporos Int. Jan
2011;22(1):223-230.
21
22
134. Ward SE, Laughren JJ, Escott BG, Elliot-Gibson V, Bogoch ER, Beaton DE. A program with a dedicated
coordinator improved chart documentation of osteoporosis after fragility fracture. Osteoporos Int. Aug
2007;18(8):1127-1136.
135. Dell RM, Greene D, Anderson D, Williams K. Osteoporosis disease management: What every orthopaedic
surgeon should know. J Bone Joint Surg Am. Nov 2009;91 Suppl 6:79-86.
136. Edwards BJ, Bunta AD, Madison LD, et al. An osteoporosis and fracture intervention program increases
the diagnosis and treatment for osteoporosis for patients with minimal trauma fractures. Jt Comm J Qual
Patient Saf. May 2005;31(5):267-274.
137. Harrington JT, Barash HL, Day S, Lease J. Redesigning the care of fragility fracture patients to improve
osteoporosis management: a health care improvement project. Arthritis Rheum. Apr 15 2005;53(2):198-
204.
138. Skelton D NF. NHS Greater Glasgow and Clyde Strategy for Osteoporosis and Falls Prevention 2006-2010:
An evaluation 2007-2009 2009.
139. McLellan AR, Wolowacz SE, Zimovetz EA, et al. Fracture liaison services for the evaluation and management
of patients with osteoporotic fracture: a cost-effectiveness evaluation based on data collected over 8
years of service provision. Osteoporos Int. Jul 2011;22(7):2083-2098.
140. Kaiser Permanente. Kaiser Permanente HealthConnect® Electronic Health Record. http://xnet.kp.org/
newscenter/aboutkp/healthconnect/index.html. Accessed 24 February, 2012.
141. Dell R, Greene D, Schelkun SR, Williams K. Osteoporosis disease management: the role of the orthopaedic
surgeon. J Bone Joint Surg Am. Nov 2008;90 Suppl 4:188-194.
142. Sander B, Elliot-Gibson V, Beaton DE, Bogoch ER, Maetzel A. A coordinator program in post-fracture
osteoporosis management improves outcomes and saves costs. J Bone Joint Surg Am. Jun 2008;90(6):1197-
1205.
143. NSW Government Health. The Orthogeriatric Model of Care: Summary of Evidence 2010. In: New South
Wales Agency for Clinical Innovation, ed. North Ryde; 2010.
144. Cooper MS, Palmer AJ, Seibel MJ. Cost-effectiveness of the Concord Minimal Trauma Fracture Liaison
service, a prospective, controlled fracture prevention study. Osteoporos Int. Jan 2012;23(1):97-107.
145. Chen JS, Hogan C, Lyubomirsky G, Sambrook PN. Management of osteoporosis in primary care in
Australia. Osteoporos Int. Mar 2009;20(3):491-496.
146. Brankin E, Mitchell C, Munro R, Lanarkshire Osteoporosis S. Closing the osteoporosis management gap
in primary care: a secondary prevention of fracture programme. Curr Med Res Opin. Apr 2005;21(4):475-
482.
147. Hippisley-Cox J, Bayly J, Potter J, Fenty J, Parker C. Evaluation of standards of care for osteoporosis and
falls in primary care 2007.
148. O’Shea C. Bones and other challenges. Aust Fam Physician. 2012;41(3):85.
149. Ebeling PR, Davenport G, Evans S, Mitchell PJ. Osteoporosis challenges. Aust Fam Physician.
2012;41(4):169.
150. British Medical Association, NHS Employers. Quality and Outcomes Framework for 2012/13: Guidance for
PCOs and practices. London 2012.
151. British Geriatrics Society. Best Practice Tariff for Hip Fracture - Making Ends Meet http://www.bgs.org.
uk/index.php?option=com_content&view=article&id=700:tariffhipfracture&catid=47:fallsandbones&Item
id=307. Accessed 15 March 2012.
152. Department of Health. Payment by Results Guidance for 2012-13. Leeds; 2012.
153. Cooper C, Mitchell P, Kanis JA. Breaking the fragility fracture cycle. Osteoporos Int. Jul 2011;22(7):2049-
2050.
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