a snapshot of our high-level speaking …for the screening scientist this enables: •...

JOIN US AS WE LAUNCH OUR NEXT DECADE OF

EXCELLENCE!

THE EXTERNALIZATION TRENDConsider key strategies to minimize cycle time and

protect your compound data when dealing with third-party research partners

Upgrade to the latest lab automation and ensure smooth integration with

existing systems

INFORMATICS AND DATA ANALYTICS

Capture, sort, store, analyze and present massive compound

data

AUTOMATION AND ROBOTICS

ASSAY DEVELOPMENT AND HTS INNOVATIONSFacilitate faster, more

flexible screening formats while reducing

waste

COMPOUND QCImplement new best practices to achieve

maximum compound purity and enable the most

accurate assays possible

SHIPPING AND LOGISTICSEnsure the proper packaging and documentation of your

compounds to streamline your workflow between remote

international sites

STREAMLINE YOUR COMPOUND MANAGEMENT

WORKFLOW

www.CompoundManagementSummit.com • 1-800-882-8684 • [email protected]

Optimize your operations to increase flexibility and

reduce cycle times

Gregory Wendel, Ph.D.Head, Sample Management and Engineering Novartis Institute for Biomedical Research

Media Partners:Sponsors:

William JanzenExecutive Director, Lead Discovery Epizyme

Kimberly MatusExternal Research Solutions – Research Operations Head Pfizer

Janet Diratsouian Associate Director Discovery Compound Management Merck

Martha LarsenHTS Director, Center for Chemical Genomics University of Michigan

A SNAPSHOT OF OUR HIGH-LEVEL SPEAKING FACULTY

September 28-30, 2015 · Hyatt Regency Boston, Boston, MA

Dear Colleague,

Welcome to IQPC’s 11th Annual Compound Management & Integrity Summit – the only event of its kind in the U.S.! To launch the next decade of our celebrated program, we’re taking a fresh look at the challenges that directly influence your compound management workflow.

Now more than ever, compound management professionals have to face the tough questions and forceful trends that are redefining not only the future direction, but also the day-to-day execution of their role. How do you expand your capabilities and support changing science while adhering to ever-tighter budget constraints? How do you process an increasing volume of compound requests with fewer staff and aging automation? How do you transfer your expertise from successes in compound management to improve the labeling, storage and handling of large molecules and biologic samples? And finally, what key factors should you consider when making the crucial decision of when, where and with whom to outsource your compound management operations?

You asked, and we’ve answered. We’re bringing you a comprehensive series of compelling sessions that address each of these questions and more in three highly interactive days. At our exclusive Boston venue, you’ll:

• Engage in the externalization debate: explore the unexpected benefits of third-party scientific partnerships, and weigh them against the advantages of keeping compound management in-house

• Adopt best practices to optimize your partnership with your CROs while protecting the intellectual property of your compounds

• Discover the newest innovative software and equipment available to accurately identify, track, store and retrieve your compounds with record speed and efficiency

• Maximize the efficiency of your existing automation to maintain high performance and prove ROI amid significant budget cuts

• Improve your informatics and data analytics tools to streamline and simplify data capture, processing and presentation

• Explore the latest developments and implementation strategies for more flexible HTS formats

• Ensure proper labeling and documentation to avoid costly delays in customs, and to ensure punctual compound delivery for assays

In a variety of panel discussions, Q&A sessions, roundtables and case studies, our high-level speakers will draw from their years of experience to share their current challenges, works in progress, newest projects, exciting success stories and lessons learned to bring you a dynamic and informative program that you cannot afford to miss. We look forward to networking with you on site!

Sincerely,

Lauren Delapenha

Register Today: www.CompoundManagementSummit.com • 1-800-882-8684 • [email protected] 2

OUR AGENDA THIS YEAR WILL HELP YOU TO...

ACCELERATE your workflow to ensure compounds meet assay schedules

PROTECT compound integrity during tracking, storage, retrieval and screening

UPGRADE from obsolete software/equipment to optimize workflow efficiency

MEET AND EXCEED increasing volume of compound requests to support changing research

ENSURE maximum compound purity to facilitate accurate screening

INCREASE efficiency of existing automation to maximize limited resources

JUSTIFY future expenditure with comprehensive data analytics

SUPPORT the higher demands of changing science

IMPLEMENT comprehensive data management software to effectively trace location and status of compounds

FACILITATE more flexible assays to achieve faster lead validation

MINIMIZE turnaround time between your library and your CRO

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3“The dynamic interaction between attendees and

dialogue during/after presentations.”

– Victoria Emerick (Bristol-Myers Squibb)


NEW THIS YEAR

At our event, you’ll be interacting with the VPs, Directors, Group Leaders, Research Scientists and Heads of…

• Compound Management

• Compound Logistics

• Sample Management Technologies

• Automation Engineering

• Systems Engineering

• Engineering Operations

• High-Throughput Screening (HTS)

• Biomolecular Screening

• Research Operations / Support

• R&D

• External Research Solutions

• Lead Optimization

• Lead Discovery

• Target Selection

• Target Validation

• Drug Discovery

• Assay Operations

• Data Analytics

• Informatics / IT

• Chemical Libraries & Analysis

• Analytical Chemistry

• Discovery Chemistry

• Molecular Pharmacology

• ADME Technology

…and many more!

• Develop Informatics Software to Track and Reduce Cycle Times

• Best Practices for Externalizing a Big Pharma Compound Collection

• Expand your Capabilities, Support Changing Science and Reduce Cost with Existing Technology

• Dealing with Automation Failure: Developing Essential Backup Strategies to Avoid Workflow Interruptions

• Compound Quality Control: Best Practices to Ensure Delivery of High Quality Samples

• During an extended networking session in the afternoon of Main Conference Day 1, our leading solution providers will give special presentations of their latest technology, on-site and in-person! This is the ideal opportunity to get your questions answered about the newest features, advantages, and drawbacks to establish vendor relationships and make smart purchasing decisions.

ABOUT THE ORGANIZER

Pharma IQ, a division of IQPC, provides useful training courses, conferences and expositions for pharmaceutical executives to network and learn the latest pharma business development and trends occurring in organizations today. Pharma IQ focuses on establishing an interactive experience featuring practical, objective, and up-to-date insight from pharma industry leaders. www.pharma-iq.com

• Who better to learn from than your peers who face the same challenges as you do? Come join us to hear first-hand from your high-level colleagues and fellow thought leaders as they share from their experience in trials, triumphs and innovations.

WHO WILL YOU BE NETWORKING WITH?

• Small molecules: Compound Quality Control: Best Practices to Ensure Delivery of High Quality Samples

• Multi-modal molecules: Building an Agile Compound Management Structure to Handle Complex Multi-Modal Molecules

• Biologic samples: Exploring the Future of Sample Management: Leveraging Capabilities from Compound to Biologics

Sharing Best Practices Across 3 Major Types of Compound Libraries: Small Molecules, Large

Multi-Modal Molecules and Biologic Samples

Interactive, Live Demonstrations of the Latest Automation, Robotics and Software

Featured Think Tanks to Address Your Major Challenges

More Compelling Case Studies

4

MONDAY SEPTEMBER 28, 2015

PRE-CONFERENCE WORKSHOP DAY

Register Today: www.CompoundManagementSummit.com • 1-800-882-8684 • [email protected]

A

ST

B

9:00am – 11:00am Registration for Workshop A: 8:30am

3:00pm-5:00pm (Registration for Site Tour: 2:15pm) The shuttle bus will depart for the site tour at 2:45pm.

11:30am – 1:30pm Registration for Workshop B: 11:15am. Lunch will be served during this workshop

Optimize your Workflow with Effective Data ManagementSo much of compound management depends on how well you handle massive quantities of data associated with the compounds in your collection. However, developing and working with databases that are robust enough to store and manipulate this data effectively presents a real challenge. In this detailed workshop, we’ll outline your most pressing data management needs and explore the various strategies and tools you can implement to address them.

What you will learn:

• Sort, prioritize and extract relevant data

• Format data into an easy-to-read interface

• Develop metrics on cycle times to pinpoint and address holdups

• Access data in record time to respond as needed

Integrating New Automation With Existing Systems to Accelerate Your Compound Management WorkflowUpdating your lab automation and robotics involves a huge financial investment. However, due to heavy usage and the increasing demands of changing science, this expensive equipment quickly becomes dated and obsolete, and often requires upgrading within a few short years. Compound managers, IT/IS teams and automation engineers are then faced with the challenge of dealing with compatibility issues between new purchases and legacy automation. In this comprehensive workshop, we’ll explore in detail the strategies and tools you need to build a flexible, fully-integrated network of automation to support your lab’s R&D needs.

SITE TOUR: See What’s New at The Koch Institute!The program will feature:

• A KI facility tour highlighting groundbreaking scientific discoveries and the new technologies that usher them to the hands of patients and physicians

• A presentation highlighting the current projects at the KI, as well as the challenges involved in integrating their newest technology

• Conversations with representatives from the KI’s faculty and leadership team

The Koch Institute is a community of more than 1,000 MIT researchers taking an unprecedented approach to creating new cancer treatments, and new tools to detect and monitor the disease. Bringing together under one roof biologists and chemists; biological, chemical and materials science engineers; computer scientists, clinicians and others, the KI has created a unique model that leverages fresh perspectives and a collaborative, interdisciplinary approach to accelerate advancements in the fight against cancer.

Supporting more than 50 laboratories, the KI’s Swanson Biotechnology Center is an on-site suite of sophisticated technology facilities run by expert staff that allows researchers to conduct and refine investigations at maximum speed and efficiency, and to optimum effect.

How you will benefit:

• Make information easily available for R&D teams to fully support their research needs

• Standardize data flow and format between biologists and chemists so they “speak the same language”

• Achieve greater transparency in your workflow to identify and address bottlenecks

Workshop leader to be announced

What you will learn:

• Explore the latest developments in lab automation and robotics that will maximize accuracy and accelerate your workflow

• Harmonize new software/hardware with existing automation to ensure smooth operation of newly-purchased equipment

• How to budget in advance for expensive automation upgrades to prepare for future needs and technological innovations

• Convert from big, monolithic systems to more agile equipment that can be upgraded and repaired more easily

• Plan a maintenance routine to extend the life of your equipment

• Train your lab staff appropriately to protect both your equipment and your employees

How you will benefit:

• Forecast and prepare for the next generation of lab automation

• Ensure compatibility between software and hardware to reduce the incidence of time-consuming performance issues

• Invest in the right automation to avoid expensive replacements and overhaul in the long run

• Increase flexibility to meet changing research needs

• Maximize the performance of your new and pre-existing automation

Workshop leader to be announced

KEYNOTE ADDRESS

7:30 Registration & Coffee

8:45 Chairperson’s Welcome and Opening Session Matt Boeckeler | Compound Management Team Leader | AstraZeneca

9:00 KEYNOTE: Compound Bank Re-Engineering – Implementing New Technologies to Enable Cutting-Edge Assay Methods

A multi-year, cross-site global re-engineering of the compound collection and infrastructure within Novartis Institute for Biomedical Research (NIBR) has resulted in dramatic improvements in speed, flexibility and capabilities. For the screening scientist this enables:

• Knowledge/data-driven subset screening

• Rapid Confirmation of screening hits to shorten screen cycle time

• Adaptive Screening: adjust focused set composition based upon early results during execution of run

• Support for multiple, flexible plate formats to facilitate the use of more challenging assay technologies

• Forecasting of the impact that compound bank re-engineering will have on your screening process

• Creation of new systems and integration paradigms that facilitate the switch to new screening technology

Gregory Wendel, Ph.D. | Head, Sample Management and Engineering | Novartis Institute for Biomedical Research

9:45 Consolidating Best Practices in Compound Management: Compare and Contrast Between Small Pharma, Big Pharma and Academia• Adjust your process depending on your environment to adapt to drastic

differences in funding and scale

• Establish robust systems when setting up a lab in order to avoid lost productivity and stock later

• Maintain good communication between compound management and

your supported teams to mitigate future problems

• Be prepared to adjust your process to meet higher volumes in order to meet changing scientific needs or technological advancements

• Communicate at senior levels to secure buy-in and funding for needed software and automation upgrades

• CASE STUDY: Integrate and organize your compound library – best practices for maintaining sub-libraries with varying handling and storage requirements including fragments, GXP, and off-site storage

William Janzen | Executive Director, Lead Discovery | Epizyme

Elizabeth Admirand | Senior Research Associate | Epizyme

10:30 Networking Break

11:15 Externalizing a Big Pharma Compound Collection• Address the challenge of moving compounds from multiple sites to a

single location

• Explore the benefits of compound consolidation

• Dealing with low-turnover, obsolete compounds by making material available to the marketplace

Dale McLeod | Senior Scientist | Pfizer

12:00 CROs: How to Maximize Your Company’s Collaboration with External Research Providers• Strategically outsource compound inventory and assays to minimize cycle

times

• Implement software to better communicate with CRO partners

• Develop infrastructure that is harmonized with internal workflows

• Standardize methods to assess compound quality between remote locations

Kimberly Matus | External Research Solutions – Research Operations Head | Pfizer

12:45 Networking Lunch Break- Lunch Will Be Provided Over a Featured Presentation.

5 Register Today: www.CompoundManagementSummit.com • 1-800-882-8684 • [email protected]

TUESDAY SEPTEMBER 29, 2015

MAIN CONFERENCE DAY 1

MAIN CONFERENCE DAY 1 Continued

1:45 Data Analytics: Making Data Work for You to Streamline your Compound Management Workflow• Maximize your use of data analytics to facilitate tactical / strategic

decision making and to promote buy-in from stakeholders• Clearly define the data needs of R&D teams to remove non-value-added

work• Standardize your data retrieval and analysis to establish a repeatable,

uniform reporting protocol • Present your data in an easily accessible format to remove guesswork

Sandra Matson | Research Scientist | Bristol-Myers Squibb

2:30 Conducting High-Throughput Screening (HTS) on a Limited Budget: Expand your Capabilities, Support Changing Science and Reduce Cost with Existing Technology• Adapt research practices to budgetary allowances to facilitate more

flexible, effective screening on a smaller scale• Involve researchers in determining the best compound libraries and

integrate medicinal chemistry expertise in maintaining compound integrity

• Adopt new technology as needed – critically assess research needs to inform your short and long-term equipment and library purchasing decisions

• Explore cheaper and faster alternatives to acoustic dispensing to save millions in automation expenditure

• Create and implement a nimble database system to manage compounds in a small biotech/academic setting

• Explore case studies in cost effective resource management that have facilitated high-level research while saving money

Martha Larsen | HTS Director | University of Michigan


3:15 ***INTERACTIVE DEMO DRIVES*** Our Sponsors Will Be Conducting Live Demonstrations of Their Latest Compound Management Solutions On-Site!

4:30 Dealing with Automation Failure: Developing Essential Backup Strategies to Avoid Workflow Interruptions (Panel Discussion)• Establish a reliable system of local support to respond to common robotic

malfunctions and errors

• Adopt strategies to avoid costly turnaround times in compound transportation between international sites

• Implement a small backup store on an offline, self-maintaining database that can supply compounds quickly in case of emergencies

• Determine when and where to implement human supervision in the increasingly automated compound management process

• Optimize efficiency of existing systems to reduce cost spent on expensive new automation and technology

Panelists: Gaianne Berrios | Head of Compound Logistics US | EMD Serono

5:15 End of Day One

“It has been incredibly pleasant to see other companies experiencing the same hardships and challenges as our company.”

– Jamie Bandouveres (Merck)

“The conference provided a great format for checking in with industry peers on their challenges in compound management. The exchange

of ideas stimulated lively discussions, with practical approaches to solving problems in workflows, hardware/software/facilities infrastructure,

and the timely meeting of business deliverables.” – Paul Taylor (Boehringer Ingelheim Pharmaceuticals, Inc.)


Forecasting the Future of a Changing Field

7:30 Registration & Coffee

8:45 Chairperson’s Welcome and Opening Session Matt Boeckeler | Compound Management Team Leader | AstraZeneca

9:00 KEYNOTE: Exploring the Future of Sample Management: Leveraging Capabilities from Compound to Biologics• Move beyond small molecule sample management to address enterprise

challenges

• Adapt best practices in compound management to apply them to emerging sample management areas, including biologics and product development

• Apply supply chain management principles in sample management

• Make informed automation and IT decisions

• Address the challenges of GLP certification

9:45 PANEL DISCUSSION: Building an Agile Compound Management Structure to Handle Complex Multi-Modal Molecules • Annotate large molecules correctly to track and retrieve compounds efficiently

• Implement a comprehensive informatics infrastructure to easily track, store, retrieve and handle multi-modal molecules

• Increase the flexibility of your compound management structure to reduce future overhaul

• Develop best practices for the management of biologics for low and high throughput applications

• Manage failure (technical, biological and quality) when there is no room for error

Moderator:

Jefferson Chin | Senior Research Scientist | Bristol-Myers Squibb

Panelists:

Karen Billeci | Senior Scientific Manager | Genentech

Bill Goode | Director of Informatics and IT | Jounce Therapeutics

10:30 Networking Break

11:15 Shipping and Logistics: Documenting, Tracking and Protecting Compounds During Transportation • Clarify the common criteria for compounds being flagged and held up in

customs in key countries: China, Italy and India

• Formulate a plan of action in advance in case compounds are detained in customs in order to minimize costly lag time

• Consolidate customs documentation requirements into an easy-to-update standard statement

• Strike the balance between declaring required compound information and protecting trade secrets

• Choose the right vendor to handle compound packages safely across long international distances

Gaianne Berrios | Head of Compound Logistics US | EMD Serono

12:00 CASE STUDY: Implementing a Comprehensive Global Ordering System to Streamline International Compound Logistics• Learn how a small, satellite location can spearhead the development of

an effective, globally-integrated compound logistics framework

• Simplify compound ordering by implementing a comprehensive query format that allows scientists to easily locate desired compounds within global inventory

• Easily track compound location across international sites to coordinate realistic assay timelines with research scientists

• Protect the integrity of compounds of interest by assigning crucial restrictions on their use and transportation

• Maintain the smooth functioning of such a large, robust LIMS system by working closely with key software providers

Kristen Nailor | Scientist, Compound Logistics | Janssen

12:45 Networking Lunch Break - Lunch Will Be Provided Over a Featured Presentation.

WEDNESDAY SEPTEMBER 30, 2015

MAIN CONFERENCE DAY 2


MAIN CONFERENCE DAY 2 Continued

1:45 Interactive Roundtables: Biologic Samples, Externalization and Informatics

Expanding from Compound to Biologic Sample Management

Standardizing Global Compound Management Operations

Developing and Optimizing Informatics Tools to Track and Reduce Cycle Times

• Transfer your small molecule compound management expertise to improve your sample management operations

• Simplify the identification and storage of biologic samples

• Integrate multiple registration and automation systems

• Extend the reach of sample management into the lab

Mark Gulbronson | Research Operations Director | Amgen

• Global Distribution: How to get the right samples, in the right place, at the right time

• Challenges of provisioning samples with commercial and bespoke IS infrastructure

• Benchmark metrics and KPI’s: What’s your measure of success?Matt Boeckeler | Compound Management Team Leader | AstraZenecaMichele Larned | Senior Research Scientist | AstraZeneca

• Format data into an easy-to-read interface• Develop metrics on cycle times to pinpoint and address holdups• Improve compound handling through real-time data tracking• Decide which informatics software best meets your company’s

compound management needs

Tom Noonan | Scientist II, Lab Automation | EMD Serono

2:45 Compound Management in Flavors & Fragrances: Overcoming Unique Challenges• Consider certain key factors in developing a compound management

group from scratch: decisions to make in hardware, software, logistics, workflow, and Q.C.

• Design accuracy and versatility into an integrated liquid handler for fragrance chemicals that are viscous, volatile, and intense

• Strike the balance between efficiency and longevity when storing samples of reactive chemicals

• Develop in-house automated data analysis quality control by GC/MS and Visual Basic: make it easy for the chemist, and understandable for the biologist

Patrick Perry | R&D Scientist | Firmenich

3:30 Afternoon coffee break – Network over refreshments

4:00 Compound Quality Control: Best Practices to Ensure Delivery of High Quality Samples• Implement QC processes in every stage of compound management to

guarantee availability of purity data along with assay results

• Enhance capabilities and/or capacity in the QC laboratory

• Implement new software tool for QC data analysis

• CASE STUDY: Inside Merck’s cutting-edge QC lab

Janet Diratsouian | Associate Director, Discovery Compound Management | Merck

4:45 CASE STUDY: Expediting Compound Collection Growth: Multi-Component Reaction (MCR) Research and the Molecular Libraries’ Small Molecule Repository• Combat the challenges of building a compound collection in academia,

and within the NIH Molecular Libraries’ Small Molecule Repository

• Maximize small molecule “Iterative Efficiency Potential” (IEP) with multi-component reactions (MCRs) to expedite the drug discovery process

• Explore successful case studies of achieving hit to IND in reduced timeframes

Dr. Christopher Hulme | Professor, Department of Pharmacology and Toxicology | University of Arizona

5:30 End of Day Two

Team Discounts

PRICING

Vendor Pricing

WAYS TO REGISTER

ABOUT THE VENUE

Package Register & Pay By8/14/15

Standard Pricing

Main Conference $1,699 (Save $300) $1,999

(Main conference + 2 Workshops, Site Tour) $2,399 (Save $200) $2,599

Individual Workshops $549

Site Tour Only $799

Package Register & Pay By8/14/15

Standard Pricing

Main Conference$2,899

(Save $200)$3,099

(Main conference + 2 Workshops, Site Tour) $3,999 (Save $200) $4,199

Individual Workshops $549

Site Tour Only $799

4

Send: Save:

Groups of 3 10%off

Groups of 4 to 5 15%off

Groups of 6 or more 20% off

*IQPC reserves the right to determine who is considered an End-User or a Vendor upon registration for an event. Those who are determined a vendor will be denied access to End-User pricing. These prices are featured as a limited time only promotion. IQPC reserves the right to increase these prices at its discretion.

Please note multiple discounts cannot be combined. A $99 processing charge will be assessed to all registrations not accompanied by credit card payment at the time of registration.

MAKE CHECKS PAYABLE IN U.S. DOLLARS TO: IQPC

*CT residents or people employed in the state of CT must add 6.35% sales tax.

Team Discounts: For information on team discounts, please contact IQPC Customer Service at 1-800-882-8684. Only one discount may be applied per registrant.

Special Discounts Available: A limited number of discounts are available for the non-profit sector, government organizations and academia. For more information, please contact customer service at 1-800-882-8684.

Details for making payment via EFT or wire transfer: JPMorgan Chase - Penton Learning Systems LLC dba IQPC: 937332641 ABA/Routing #: 021000021 Reference: 10516.010

Payment Policy: Payment is due in full at the time of registration and includes lunches and refreshment. Your registration will not be confirmed until payment is received and may be subject to cancellation.

For IQPC’s Cancellation, Postponement and Substitution Policy, please visit www.iqpc.com/cancellation

Special Dietary Needs: If you have a dietary restriction, please contact Customer Service at 1-800-882-8684 to discuss your specific needs.

Hyatt Regency Boston One Avenue De Lafayette, Boston, Massachusetts02111, United States Website: http://regencyboston.hyatt.com Phone: 617-521-6333

The special room rate of $299 has been established to make your reservation process easy. Simply call 1-888-421-1442 and give the group name 11th Compound Management or book through our group reservation link https://resweb.passkey.com/go/IQP2015 no later than September 7, 2015. In addition the special rate has been extended to three days before and after the conference

Metrics and Performance management are initiatives that require buy-in across the IT leadership team to ensure effectiveness. In order to maximize business results generated by your IT organization, take advantage of our group discounts by attending with your entire IT leadership team.

*Discounts apply to registrations submitted together, at the same time. Cannot be combined with any other discount

©2015 IQPC. All Rights Reserved. The format, design, content and arrangement of this brochure constitute a trademark of IQPC. Unauthorized reproduction will be actionable under the Lanham Act and common law principles.


PRICING & REGISTRATION

www.CompoundManagementSummit.com

1-800-882-8684

[email protected]

212-973-1042

a snapshot of our high-level speaking …for the screening scientist this enables: •...

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