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A L I M E N T A T I O N A G R I C U L T U R E E N V I R O N N E M AERES September 17th , 2009 Collaborative research, intellectual property and technology transfer

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Page 1: A L I M E N T A T I O N A G R I C U L T U R E E N V I R O N N E M E N T AERES September 17th, 2009 Collaborative research, intellectual property and technology

A L I M E N T A T I O N

A G R I C U L T U R E

E N V I R O N N E M E N T

AERES September 17th , 2009

Collaborative research, intellectual property and technology transfer

Page 2: A L I M E N T A T I O N A G R I C U L T U R E E N V I R O N N E M E N T AERES September 17th, 2009 Collaborative research, intellectual property and technology

A L I M E N T A T I O N

A G R I C U L T U R E

E N V I R O N N E M E N T

AERES September 17th , 2009

Direction de la Valorisation DV INRA

•Launched in 2001, directly depending on the general board of INRA.

•An original integrated economical model, active since 2003 : dynamic balance between the revenues of royalties collected by two private subsidaries INRA Transfert Inc and Agri Obtentions Inc and the expenses invested by INRA for the protection of the intellectual property, the incentive measurements for the financial return to innovative scientists, collective return to the scientific units, and financing of the services ordered by INRA and achieved by its subsidaries.

•A unique management integrated by DV INRA for the two INRA units DV UCPI and DV DPE and the two subsidaries IT and AO.

•A double network of skills for the negociation of contracts : public partnership in the 21 regional centers, private partnership in the 14 scientific departments.

Page 3: A L I M E N T A T I O N A G R I C U L T U R E E N V I R O N N E M E N T AERES September 17th, 2009 Collaborative research, intellectual property and technology

A L I M E N T A T I O N

A G R I C U L T U R E

E N V I R O N N E M E N T

AERES September 17th , 2009

Direction de la Valorisation DV UCPI

•Missions of the unit DV UCPI : contract law and intellectual property.

A legal staff of 15 skills higly specialized in the field of DV INRA, a critical mass of expertise( back office ) supporting the general activities of collaborative research achieved in the two previous networks ( front office ).

A relevant expertise for the european consortium agreements, framework agreements with the private sector, finalization of complex contracts.

The management of the following strategic portfolio of INRA : invention disclosures, patents, trademarks, databases and softwares.

The management each month of the intellectual property national committee : recommandations and decisions for the filings, the extensions and the abandons.

Page 4: A L I M E N T A T I O N A G R I C U L T U R E E N V I R O N N E M E N T AERES September 17th, 2009 Collaborative research, intellectual property and technology

A L I M E N T A T I O N

A G R I C U L T U R E

E N V I R O N N E M E N T

AERES September 17th , 2009

Direction de la Valorisation DV DPE

•Missions of the unit DV DPE : stimulating and encouraging the partnership with private companies.

8 skills located in the west of France, launched in 2003.

Expertise in the use of ICT dedicated to the internal communication with the scientists and the external dissemination of our results towards our partners.

Economical and industrial survey to stimulate our strategic private partnerships.

A national mission for the coordination of our collaborative research implemented within the network of the french regional clusters « Pôles de compétitivité ».

Launching in 2008 of the network of our Phd students supported by industry.

Annual reporting and follow up of the indicators in the field of DV.

Page 5: A L I M E N T A T I O N A G R I C U L T U R E E N V I R O N N E M E N T AERES September 17th, 2009 Collaborative research, intellectual property and technology

A L I M E N T A T I O N

A G R I C U L T U R E

E N V I R O N N E M E N T

AERES September 17th , 2009

« En direct des labos » et « Live from the labs » two electronic free of charge newsletters for our socio-

economic partners

4380 partners have subscribed in France…. and 360 outside Francewww.inra.fr/en_direct_des_labos www.international.inra.fr/live_from_the_labs

Aims and objectives :• Providing our private partners, through a professional and attractive tool, with the researches conducted and the results achieved in INRA, • Meeting the industrial needs and stimulating the demand of research, • Establishing relationships between researchers and private companies in France and Europe,• Facilitating the cooperation with the best INRA scientific teams.

Page 6: A L I M E N T A T I O N A G R I C U L T U R E E N V I R O N N E M E N T AERES September 17th, 2009 Collaborative research, intellectual property and technology

A L I M E N T A T I O N

A G R I C U L T U R E

E N V I R O N N E M E N T

AERES September 17th , 2009

Collaborative research with industry technology transfer process

Research contracts with

the private companies

Research projects on own funds

Contract research projects: European

projects, ANR,...

Intellectual Property

205 families of patent applications

163 softwares or databases 56 trademarks

508 “Certificats d’Obtention Végétale”

234 contracts with private companies

9.9 M€ funding from private companies

234 contracts with private companies

9.9 M€ funding from private companies

Filing of 15 to 20 proposals of european project each year

Management of 12 european projects coordinated by INRA

Page 7: A L I M E N T A T I O N A G R I C U L T U R E E N V I R O N N E M E N T AERES September 17th, 2009 Collaborative research, intellectual property and technology

A L I M E N T A T I O N

A G R I C U L T U R E

E N V I R O N N E M E N T

AERES September 17th , 2009

ANNUAL FLOW OF NEW RESEARCH CONTRACTS WITH INDUSTRY, NEW PATENT APPLICATIONS AND NEW LICENSES

Page 8: A L I M E N T A T I O N A G R I C U L T U R E E N V I R O N N E M E N T AERES September 17th, 2009 Collaborative research, intellectual property and technology

A L I M E N T A T I O N

A G R I C U L T U R E

E N V I R O N N E M E N T

AERES September 17th , 2009

Open innovation and strategic private partnerships

A wave of « framework agreements » to be consolidated or developed with the most important private international groups of our sectors.

Stimulated and encouraged by the dynamics of open innovation and the incentive measurements of the french government ( « research tax credit » )

Animal health : PFIZER, MERIAL, CEVA, SCHERING INTERVET.

Animal production and selection (AGENAE ) : EVIALIS, GLON SANDERS, UNCEIA,GRIMAUD.

Food industry : NESTLE, DANONE, UNILEVER, PERNOD RICARD, BONGRAIN, BONDUELLE, LACTALIS, CHARAL.

Ingredients : DANISCO, LALLEMAND, CH HANSEN, LESAFFRE, ROQUETTE.

Seed industry (GENOPLANTE) : LIMAGRAIN, SYNGENTA, BCS.

Green chemistry and energy ( FUTUROL) : TOTAL, IFP, DANISCO GENENCOR, DSM, TATE and LYLE, NOVOZYMES.

Ecotechnologies : VEOLIA, SUEZ.

Page 9: A L I M E N T A T I O N A G R I C U L T U R E E N V I R O N N E M E N T AERES September 17th, 2009 Collaborative research, intellectual property and technology

A L I M E N T A T I O N

A G R I C U L T U R E

E N V I R O N N E M E N T

AERES September 17th , 2009

Open innovation and strategic private partnerships : future perspectives

The most exciting and attractive developments for collaborative research to be prepared by INRA are expected in the following key sectors for the next ten years

NUTRITION, FOOD FOR HEALTH

ANIMAL HEALTH

GREEN AND WHITE BIOTECHNOLOGIES FOR BIOMATERIALS, BIOPRODUCTS AND BIOENERGY.

ECOTECHNOLOGIES

Page 10: A L I M E N T A T I O N A G R I C U L T U R E E N V I R O N N E M E N T AERES September 17th, 2009 Collaborative research, intellectual property and technology

A L I M E N T A T I O N

A G R I C U L T U R E

E N V I R O N N E M E N T

AERES September 17th , 2009

Agri obtentions : key figures

Sales figures : 9 M Euros

Staff : 42 persons

Over 400 licence-holders

10 different species groups

Head office : Guyancourt

2 Units : Guyancourt, Clermont- Ferrand

Creation : October 1983The Sustainable Agriculture’s Seed

Breeder

Page 11: A L I M E N T A T I O N A G R I C U L T U R E E N V I R O N N E M E N T AERES September 17th, 2009 Collaborative research, intellectual property and technology

A L I M E N T A T I O N

A G R I C U L T U R E

E N V I R O N N E M E N T

AERES September 17th , 2009

Research contracts with

the private companies

Research projects funded on own

support

Pre seed of life science projects

Licenses

Start up

Contract research projects: European projects, ANR,...

Technology transfer of plant varieties

Proof of concept

1,127 licenses on varieties 4,6 M€ plant varieties royalty

4,6 M€ of varieties sales turnover

Page 12: A L I M E N T A T I O N A G R I C U L T U R E E N V I R O N N E M E N T AERES September 17th, 2009 Collaborative research, intellectual property and technology

A L I M E N T A T I O N

A G R I C U L T U R E

E N V I R O N N E M E N T

AERES September 17th , 2009

Floral ornamental species

Cereals

Pulses crop

Forage and Grain corn

Oil seed crops and fibre

Forage crops

Vegetables

Fruit trees

Forest trees

Vines

Agri obtentions : portfolio 10 different species groups - over 450 varieties

Oil seed crops and fibre plantsOil seed rape: Sun, Bambin

Lin seed : Everest, Eole, Hermès,

Sunflower : Inbred linesHybrids :Inoui, Inoll, Instinct

Pulses crops

Field bean : Disco, Mélodie,Diva

Lupin : Lumen, Ludic

Pea : Isard, Apollo, GalacticCereals

Oat : Fringante, Fervente

Wheat : Ressor, Ephoros, Farandole,

Durum wheat : Duriac, Duetto, Argeles

Triticale : Collégial, Talentro, Maximal

Forage cropsCocksfoot : Ludac, Lupré, Lude

Alfalfa: Magali, Luzelle

Red clover : Diadem, Diper

Fodder beet : Colosse

Fruit treesApple : Ariane - Pear : Angelys

Peach: Caprice - Cherry : Primula

Apricot : Bergarouge

Vegetables

Garlic: Clerdor ®, Flavor®

Shallot : Vigarmor

Endigia : Isatis, Makis, Selkis

Lens : Anicia

Floral ornamental species

Ranunculus : Friandine®, Pauline®

Anemone : Marianne®, Tetranemone®

Caryopteris : Le Grand Bleu

Coteonaster : Belka

Wine grape : Marselan, Caladoc

Vines

Forage and Grain cornInbred linesHybrids : Brait, Supermonark

Elms: Lutèce® Poplar : A4A

Forest trees

Page 13: A L I M E N T A T I O N A G R I C U L T U R E E N V I R O N N E M E N T AERES September 17th, 2009 Collaborative research, intellectual property and technology

A L I M E N T A T I O N

A G R I C U L T U R E

E N V I R O N N E M E N T

AERES September 17th , 2009

Sales figures : 8.4 M€ (5,9 M€ royalties, 0,9 M€ EU grants, 1,6 M€ INRA services)

Staff : 24 persons

(PHD in science, experience in enterprise, pay variable on objectives)

Head office : Paris

5 Units : Clermont-Ferrand, Sophia-Antipolis, Rennes, Montpellier, Nantes

Collaboration with SupAgro Montpellier, Agrocampus West and Clermont-Ferrand University

Creation : February 2001

Setting up of Agro Biotech Accelerator in joint venture with Seventure (groupe NATEXIS)

INRA Transfert: key figures

Page 14: A L I M E N T A T I O N A G R I C U L T U R E E N V I R O N N E M E N T AERES September 17th, 2009 Collaborative research, intellectual property and technology

A L I M E N T A T I O N

A G R I C U L T U R E

E N V I R O N N E M E N T

AERES September 17th , 2009

Research contracts with

the private companies

Research projects funded on INRA

support

Pre seed of life science projects

Licenses

Start up

Contract research projects: European projects, ANR,...

320 license agreements 5.8 M€ of annual fees

Technology transfer process

Proof of concept and

development of projects.

“Prevalorisation” program : providing funding directed towards development of INRA technology to a point suitable

for commercialization10 projects granted each year

600 K€ annual support

Page 15: A L I M E N T A T I O N A G R I C U L T U R E E N V I R O N N E M E N T AERES September 17th, 2009 Collaborative research, intellectual property and technology

A L I M E N T A T I O N

A G R I C U L T U R E

E N V I R O N N E M E N T

AERES September 17th , 2009

INRA LICENSES IT REVENUES

Page 16: A L I M E N T A T I O N A G R I C U L T U R E E N V I R O N N E M E N T AERES September 17th, 2009 Collaborative research, intellectual property and technology

A L I M E N T A T I O N

A G R I C U L T U R E

E N V I R O N N E M E N T

AERES September 17th , 2009

Research contracts with

the private companies

Research projects on own funds Licenses

Start up

Contract research projects: European projects, ANR,...

Prove of concept and

development of projects

Pre seed of life science projects

Start up development effort

Intellectual Property

3 to 5 start up projects each year40 start up created since 1999250 jobs created and active in 2009

Page 17: A L I M E N T A T I O N A G R I C U L T U R E E N V I R O N N E M E N T AERES September 17th, 2009 Collaborative research, intellectual property and technology

A L I M E N T A T I O N

A G R I C U L T U R E

E N V I R O N N E M E N T

AERES September 17th , 2009

OVERVIEW OF THE YOUNG INNOVATIVE COMPANIES CREATED

FROM INRA RESEARCH RESULTS

Page 18: A L I M E N T A T I O N A G R I C U L T U R E E N V I R O N N E M E N T AERES September 17th, 2009 Collaborative research, intellectual property and technology

A L I M E N T A T I O N

A G R I C U L T U R E

E N V I R O N N E M E N T

AERES September 17th , 2009

Plant A = CMS OGU INRA, male

sterile

Plant B : pollen giver harbouring fertility restorer

Rfo gene

X

Canola or oilseed rape hybrid seed production

(100% hybrid between A et B)

Production of hybrid male fertile varieties with low glucosinolate content

INRA patent on protoplast fusion (FR 8304298)

INRA PATENT CMS OGU

(FR 9011670)

2002 : ADVANTA patent WO9702737 assigned to INRA

2002 : crosslicence PIONEER and INRA (to avoid assert against INRA licensies

2002 : INRA patent EP 03291677,7

for low glucosinolate fertility restorer

(useful in a complementary way to ease access to genetic

material required for crossings)

42 non

exclusive

licenses

2008 3.8M€

royalties

How INRA has built a worldwide leading patent pool through financial deals and cross license agreements…

2005 : INRA bought 3 patents kosena from MITSUBISHI

(to avoid conflict risks)