a case of bifurcation stenting- dr zarrar
DESCRIPTION
a case of bifurcation PCI with detailed reviewTRANSCRIPT
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CASE OF THE WEEK
BY
DR. M. ZARRAR ARIF
PGR CARDIOLOGY
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HISTORY
PATIENT DATA
Name: Babar Abbas
Age / Gender : 45 y / Male
MOA : Medical Emergency
DOA : 11-03-2011
Address: 149 F Model Town, Lahore
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HISTORY
PRESENTING COMPLAINTS
Chest pain for last 2 hours
HOPI
Patient was in usual state of health when he developed complaints of sudden chest pain, central in location, radiating to left arm and neck, severe in intensity and was associated with sweating. No complaints of nausea, vomiting, palpitations or dyspnoea.
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HISTORY
Past History
Patient gives history of admission with chest pain 2 days back for which he was admitted in Ittefaq hospital and he was advised stay for evaluation after an ECG but he was discharged on his request.
No previous history of any other hospital stay, surgical interventions etc
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HISTORY
Drug History
Patient has been taking following medications since last 2 days
Asprin 75 mg OD
Clopidogrel 75 mg OD
Atorvastatin 20 mg HS
Metoprolol 25 mg BD
Lisinopril 5 mg HS
No history of drug allergy.
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HISTORY
Personal History
Patient has no history of smoking or any other addiction
Occupational History
Patient is a school teacher by profession
Family History
No history of DM, IHD in the family
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GPE
A middle aged man sitting in bed well oriented in time place and person with vitals
Pulse : 72 / min, regular, normal character with no radio-radial and no radio-femoral delay.
B.P : 160/100 mm Hg
Temp : 980 F
R/R : 16 / min
-ve for Pallor, clubbing, cyanosis.
JVP not raised.
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SYSTEMIC EXAMINATION
Cardio Vascular System
On pre-cordial examination inspection normal, on palpation apex beat in 4th intercostal space with normal character, on auscultation first and second heart sounds normal with no added sound.
Respiratory System
Normal findings on inspection palpation and percussion with normal vesicular breathing bilaterally and no added sounds on auscultation.
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SYSTEMIC EXAMINATION
Gastro Intestinal System
Normal findings on inspection with no palpable visceromegally and no area of tenderness on palpation, normal bowel sounds on auscultation.
Central Nervous System
Grossly intact HMF with no motor or sensory loss
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Provisional Diagnosis
• Acute Coronary Syndrome
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INVESTIGATIONSInvestigation Result
Hb 14.3
B/Urea 30
S/Creatinine 0.9
S/Na+ 138
S/K+ 4
Troponin T (Kit Method) -ve
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ECG
ECG findings are as below
It showed regular sinus rhythm with rate of 80/min, normal axis with normal PR, and QT intervals with normal QRS.
STT changes were present in anterior chest leads from V1-V4 in form of ST segment depression and T wave inversions, no ST elevations seen in any leads.
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FINAL DIAGNOSIS
UNSTABLE ANGINA
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TREATMENT
Emergency management was done with
S/L angisid 0.5 mg stat
Asprin 300 mg stat
Clopidogrel 300 mg stat
Morphine 3mg stat
Metoprolol 25 mg stat
Infusion of isoket @ 10 u drops/min
Clexane 80 mg S/C Stat
Chest pain improved with medication and
ECG also showed improvement
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TIMI RISK SCORE
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CORONARY ANGIOGRAM
• Patient was offered coronary angiogram as it was Class I A indication according to AHA guidelines
• Recommendations for Coronary Angiography in Unstable Coronary Syndromes
Class I
High- or intermediate-risk unstable angina that stabilizes after initial treatment. (Level of Evidence: A)
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REVISED TIMI RISK SCORE
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DECISION
Patient was advised PTCA for his disease and for the complete decision we will have
to review the type of lesion we r facing
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How to define a bifurcation lesion ?
• “A coronary artery narrowing occurring adjacent to, and/or involving, the origin of a significant side branch"
• A significant SB is a branch that you don't want to loose in the global context of a particular patient
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Difficulties of Bifurcation PCI
• Risk of peri-procedural complications• Relatively high re-stenosis• Not all lesions are the same :
- Size of vessels (Meaningful SB size ≥2.25mm)
- Variable plaque distribution - Extent of SB disease - Variable angulations
• Higher risk of stent thrombosis• PCI techniques are mainly based on
personal experiences from skilled operators
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Factors to be considered for PCI strategy
• Anatomical factors– LMCA bifurcation– Location of plaque (Anatomical classification)– Plaque or carina shift– Angle between SB and MB– Dynamic change in bifurcation anatomy
• Modalities for objective anatomical evaluation– QCA, IVUS, FFR
• Selection of devices and strategies– DES vs. BMS– Single vs. Double stent techniques– Kissing balloon or not– Dedicated bifurcation stents
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Classification ofBifurcation Lesions
• Plaque Location• Plaque Extent• Angle
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Classifications of bifurcation lesions
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Medina Classification
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Limitations ofthe Medina classification
• Does not take into account1. Length of disease in the ostium of
the SB
2. Length of the LMCA before the bifurcation
3. Trifurcation
4. Vessel angulation
• The LMCA differs from many other bifurcation lesions due to the importance of the SB (LCx)
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Plaque Burden at the SB Ostium
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Trifurcation
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Angulation
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Fractal geometry and QCA
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How to name a bifurcation lesion
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Medina Classification
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SIDE BRANCH LOSS
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Simple
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Stents and Dedicated Delivery Systems
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Drug-eluting Stents in Bifurcation Lesions – Safety Data
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The Technique Matters more than the Number of Stent ?
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CONCLUSION
In cases where there is no lesion in the side branch or a purely ostial lesion, stenting the main branch with a jailed wire in the side branch followed by provisional T-Stenting of the side branch after guide wire exchange appears to be the most rational and successful strategy, provided that final kissing-balloon inflations are systematically performed.
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KEEP YOUR GOAL IN SIGHT
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WORK HARD
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SUCCESS WIL BE YOURS
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THANK YOU !!!