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Catalog no. 90364, June 2011, 831 pp.ISBN: 978-1-4200-9036-9
$149.95 / £95.00
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Biomedical optics holds tremendous promise to deliver effec-tive, safe, non- or minimally invasive diagnostics and target-ed, customizable therapeutics. Handbook of BiomedicalOptics provides an in-depth treatment of the field, includingcoverage of applications for biomedical research, diagnosis,and therapy. It introduces the theory and fundamentals ofeach subject, ensuring accessibility to a wide multidisciplinaryreadership. It also offers a view of the state of the art and dis-cusses advantages and disadvantages of various techniques.
Organized into six sections, this handbook: • Contains introductory material on optics and the optical properties
of tissue • Describes the various forms of spectroscopy and its applications in
medicine and biology, including methods that exploit intrinsic absorption and scattering contrast; dynamic contrast; and fluorescence and Raman contrast mechanisms
• Provides extensive coverage of tomography from the microscopic (optical coherence tomography) to the macroscopic (diffuse opticaltomography) to photoacoustic tomography
• Discusses cutting-edge translations to biomedical applications in both basic sciences and clinical studies
• Details molecular imaging and molecular probe development• Highlights the use of light in disease and injury treatment
The breadth and depth of multidisciplinary knowledge inbiomedical optics has been expanding continuously and
exponentially, thus underscoring the lack of a singlesource to serve as a reference and teaching tool for
scientists in related fields. Handbook ofBiomedical Optics addresses this need, offering
the most complete up-to-date overview ofthe field for researchers and students alike.
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FEATURES • An in-depth introduction to the field,
including applications for biomedicalresearch, diagnosis, and therapy
• Includes the theory and fundamentalsof each subject with the aim of accessibility to a wide multidisciplinaryreadership
• Discusses advantages and disadvantagesof various state-of-the-art techniques
• Introduces the principles of optics,lights sources, and irradiation; as wellas basic concepts in tissue optics
• Covers spectroscopic methods, including tomographic imaging, microscopic imaging methods, molecular probe development, andphototherapy
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CRC Press/Taylor & Francis Group1-800-634-7064 • 1-561-994-0555 • +44 (0) 1235 400 524
e-mail: [email protected]: www.crcpress.com
CONTENTS
Preface, David A. Boas, Constantinos Pitris, and Nimmi Ramanujam
I. BackgroundGeometrical Optics, Ting-Chung PoonDiffraction Optics, Colin SheppardOptics: Basic Physics,
Raghuveer ParthasarathyLight Sources, Detectors, and Irradiation
Guidelines, Carlo Amadeo Alonzo,Malte C. Gather, Jeon Woong Kang,Giuliano Scarcelli, and Seok-Hyun Yun
Tissue Optical Properties, Alexey N. Bashkatov, Elina A. Genina,and Valery V. Tuchin
II. Spectroscopy and SpectralImaging
Reflectance Spectroscopy, Sasha McGee,Jelena Mirkovic, and Michael Feld
Multi/Hyper-Spectral Imaging, Costas Balas, Christos Pappas, and George Epitropou
Light Scattering Spectroscopy, Le Qiu,Irving Itzkan, and Lev T. Perelman
Broadband Diffuse OpticalSpectroscopic Imaging, Bruce J. Tromberg, Albert E. Cerussi, So-Hyun Chung, Wendy Tanamai, andAmanda Durkin
Near Infrared Diffuse CorrelationSpectroscopy for Assessment ofTissue Blood Flow, Guoqiang Yu,Turgut Durduran, Chao Zhou, Ran Cheng, and Arjun G. Yodh
Fluorescence Spectroscopy, Darren Roblyer, Richard A. Schwarz,and Rebecca Richards-Kortum
Raman, SERS and FTIR Spectroscopy,Andrew J. Berger
III. Tomographic ImagingOptical Coherence Tomography:
Introduction and Theory, Yu Chen,Evgenia Bousie, Constantinos Pitris,and James G. Fujimoto
Functional Optical CoherenceTomography in Preclinical Models,Melissa C. Skala, Yuankai K. Tao, Anjul M. Davis, and Joseph A. Izatt
Optical Coherence Tomography:Clinical Applications, Brian D. Goldberg,Melissa J. Suter, Guillermo J. Tearney,and Brett E. Bouma
Forward Models of Light Transport inBiological Tissue, Andreas H. Hielscher,Hyun Keol Kim, and Alexander K. Klose
Inverse Models of Light Transport,Simon Arridge, Martin Schweiger, and John C. Schotland
Laminar Optical Tomography, Sean A. Burgess and Elizabeth M. C. Hillman
Diffuse Optical Tomography usingContinuous Wave and FrequencyDomain Imaging Systems, Subhadra Srinivasan, Scott C. Davis,and Colin M. Carpenter
Diffuse Optical Tomography: TimeDomain, Juliette Selb, and Adam Gibson
Photoacoustic Tomography andUltrasound-Modulated OpticalTomography, Changhui Li, Chulhong Kim, and Lihong V. Wang
Optical and Photoacoustic MolecularTomography of Small Animals, Vasilis Ntziachristos
IV. Microscopic ImagingAssesing Microscopic Structural
Features Using Fourier-Domain LowCoherence Interferometry, Robert N. Graf, Francisco E. Robles,and Adam Wax
Phase Imaging Microscopy: BeyondDarkfield, Phase and DifferentialInterference Contrast Microscopy,Chrysanthe Preza, Sharon V. King,Nicoleta M. Dragomir, and Carol J. Cogswell
Confocal Microscopy, William C. Warger II,Charles A. DiMarzio, andMilind Rajadhyaksha
Fluorescence Microscopy withStructured Excitation Illumination,Alexander Brunner, Gerrit Best, Roman Amberger, Paul Lemmer,Thomas Ach, Stefan Dithmar, Rainer Heintzmann, and Christoph Cremer
Nonlinear Optical Microscopy forBiology and Medicine, Daekeun Kim,Heejin Choi, Jae Won Cha, and Peter T. C. So
Fluorescence Lifetime Imaging Micro-scopy, Endoscopy and Tomography,James McGinty, Clifford Talbot, Dylan Owen, David Grant, Sunil Kumar,Neil Galletly, Bebhinn Treanor, Gordon Kennedy, Peter M. P. Lanigan,Ian Munro, Daniel S. Elson, Anthony Magee, Dan Davis, Gordon Stamp, Mark Neil, Christopher Dunsby, and Paul W. M. French
Application of Digital HolographicMicroscopy in Biomedicine, Christian Depeursinge, Pierre Marquet,and Nicolas Pavillon
Polarized Light Imaging of BiologicalTissues, Steven L. Jacques
V. Molecular Probe DevelopmentMolecular Reporter Systems for Optical
Imaging, Walter J. Akers, andSamuel Achilefu
Nanoparticles for Targeted Therapeuticsand Diagnostics, Timothy Larson, Kort Travis, Pratixa Joshi, and Konstantin Sokolov
Plasmonic Nanoprobes for BiomolecularDiagnostics of DNA Targets, Tuan Vo-Dinh, and Hsin-Neng Wang
VI. PhototherapyPhotodynamic Therapy, Jarod C. Finlay,
Keith Cengel, Theresa M. Busch, andTimothy C. Zhu
Low Level Laser and Light Therapy,Ying-Ying Huang, Aaron C-H Chen,and Michael R. Hamblin
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Handbook of Biomedical Optics
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