ADDITIONAL STUDIES7

136

7.1 PUBLIC CONSULTATION

The proposed project site is situated in Chincholi MIDC area. Hence, as per Environmental

Impact Assessment (EIA) Notification No.S.O.1533 (E) dated 14th

September 2006; and

amendment there at the proposed project does not requires conducting of public hearing. The

EIA report has been complied by incorporating required information with regards to the

project as mentioned in the Terms of Reference (TORs) issued by EAC to Sri Krishna

Pharmaceuticals Ltd (SKPL), MIDC Chincholi, Tal.: Mohol, Dist.: Solapur during 3rd

EAC

meeting held on 18.01.2016.

7.2 RISK ASSESSMENT REPORT

Under proposed manufacturing facility, bulk drug & intermediates will be manufactured by

batch production and will be carried out on campaign basis. General production process for

proposed products consist of

1. Various organic reactions in 2 to 3 stages in various solvent mediums 2. Recovery of solvents by batch distillation for recycles and reuse of solvents. 3. Layer separations and recovery of crystallized product by centrifuge. 4. Drying operation to get the final product.

7.3 HAZARD IDENTIFICATION

7.3.1 Classification of Chemicals:

In a chemical industry for primary hazard identification, classification of different chemicals

is an important factor. The classification of chemicals to be used by SKPL is presented in

following table-

Table 7.1 Classification of Chemicals used in SKPL

Group of

Chemical

Group

Members

Handling Spill Emergency Storage

Flammable

Liquids

OPDA

MAA

O-Xylene

BCP

Toluene

MIBK

Methanol

Ammonia

DMF

Acetone

PNBA

Iron power

Control of

electrostatic

charges.

Non-sparking

tools.

Containment

Inertisation.

Spill control

material

Eye/skin/

breathing PPE

Fire safety

training.

Contain

spill.

Prevent

mixing with

water

sources.

Refer TREM

card.

Arrest leak

by closing the

valve if is

safe to do so.

Contact local

police/

supplier

Take vehicle to

safe area

without

endangering life

Place warning

signs around the

vehicle.

Prevent crowd

approach to the

vehicle.

Contact local

police/supplier

Assist

emergency team

as per the need.

Ventilated place

Containment

Leak detectors

Absence of

oxidizers

Fire protection

system

Non sparking

tools

FLP fixtures as

per IS

Hot work

permits system.

Spill control

material.

Flame arrester

for storage tanks

ADDITIONAL STUDIES7

137

Group of

Chemical

Group

Members

Handling Spill Emergency Storage

Reactive

Chemicals

Caustic Lye

(48%)

MIBK

Thionyl

chloride

H2SO4

Iron power

Refer MSDS

before

handling

Avoid

incompatible

materials

around

handling area.

Ensure

inertisation

Make

available

compatible

fire

extinguishers.

Avoid

shocks/drops

and rolling

while

handling

containers.

Ensure

inertisation

while

charging in to

reactors.

Contain spill.

Prevent

mixing with

water

/moisture

Refer TREM

card.

Arrest leak by

closing the

valve if is

safe to do so.

Contact local

police/

supplier

Take vehicle to

safe area

without

endangering life

Place warning

signs around the

vehicle.

Prevent crowd

approach to the

vehicle.

Contact local

police.

Assist

emergency team

as per the need.

Refer MSDS for

compatibility

before storage.

Store air reactive

materials under

nitrogen.

Store water

reactive

materials away

from water/

moisture/

Aqueous

solutions.

Use visible sign

boards for

warning about

hazards and

cautions for

responders.

Make available

compatible fire

extinguishers.

Do not store the

materials in

flammables

storage area.

Avoid

shocks/drops

and rolling

while handling

containers.

Ensure water

layer above

Raney/Ni

catalyst all the

times

Oxidizers Conc. HCl

(30%)

Acetic acid

H2SO4

Refer MSDS

before

handling

Avoid

incompatible

materials

around

handling area.

Ensure

inertisation

Make

available

compatible

Contain spill.

Prevent

mixing with

flammables

combustibles

Refer TREM

card.

Arrest leak

by closing the

valve if is

safe to do so.

Contact local

police/

Take vehicle to

safe area

without

endangering life

Place warning

signs around the

vehicle.

Prevent crowd

approach to the

vehicle.

Contact local

police

Assist

Do not store

with flammables

and

combustibles

Do not store

with reducers.

Exclusive

storage place

advisable.

ADDITIONAL STUDIES7

138

Group of

Chemical

Group

Members

Handling Spill Emergency Storage

fire

extinguishers.

Avoid

shocks/drops

and rolling

while

handling

containers.

supplier

emergency team

as per the need.

Corrosive

Liquids

Conc. HCl

(30%)

Acetic acid

H2SO4

Chlolro

Sulphonic

Acid

Wear full

gloves,

respirator

with face

shield and

body

protection

while

handling.

Ensure

neutralizing

agents

nearby.

Contain spill.

Prevent

mixing with

flammables/c

ombustibles

Refer TREM

card.

Arrest leak

by closing the

valve if is

safe to do so.

Contact local

police/

supplier

Wear all the

PPE kept in

vehicle

before

handling

spill.

Spread

neutralizing

agent like

Calcium

oxide/ash

liberally on

the spill.

Take vehicle to

safe area

without

endangering life

Place warning

signs around the

vehicle.

Prevent crowd

approach to the

vehicle.

Contact local

police/supplier

Assist

emergency team

as per the need.

Consider

secondary

containment.

Store on non-

corrosive

surface

Consider local

exhaust system

Store away

from azides,

sulphides, and

hydrosulphides

and metal

powders.

Separate

organic acids

and In-organic

acids.

Segregate

water reactive

corrosive

liquids from

water moisture

and aqueous

solutions.

Keep

neutralizing

agents nearby.

Store

containers on

sand bed.

Display board

at the entrance

to avoid use of

water or water

based

extinguishers

during fire

fighting.

ADDITIONAL STUDIES7

139

7.3.2 Risk Prone Areas

Based on classification of chemicals the hazard prone areas have been identified as follows-

Reaction and separation Sections

Storage of chemicals in tanks or respective vessels

Handling of the materials or the process equipment by the operator or worker.

Transportation of the products and raw materials.

Underground Storage tank.

7.3.2.1 Reaction and Separation Sections

Major hazard in this section is of fire, explosion leading to toxic release. Extent of the

damage depends on the hazardous properties of the reactants, reaction and separation

conditions. Minimum risk is of most importance and this can be achieved by selecting an

intrinsically safe process and optimizing operating process parameters near to the

atmospheric conditions. But this is not possible most of the time. Hence, it is necessary to

install safe guards and build in perfect operating procedure that will minimize chances of

accident to the minimum. Also types of reaction taking place during the process are of prime

importance. It may be exothermic or endothermic. The same will be followed for the

expansion product facilities.

Exothermic Reactions.

HAZOP studies will be carried out for potentially dangerous and hazardous reactions in the

manufacturing of products. The reaction includes the chlorination in the production of folic

acid in stage II. All safety features will be designed to mitigate the risk and hazard to

minimum. For controlling exothermic reaction