7 Ways to Improve YourLiposuction Results

Karen CronholmProduct ManagerApril 21, 2011

What value does Smartlipo TriPlex add to my practice?

There are 7 Ways…….

Reason #1

Smartlipo’s unique technology improves patient outcomes

Reduced Pain, Less Downtime

Data courtesy of Gordon Sasaki, MD Presented ASPS October 2009

Patients back to work 50% faster and

experienced less pain compared to liposuction alone

Laser Lipolysis by Smartlipo

• The first of it’s kind! Unique technology

• tighten tissue through coagulation

• rupture fat cells for easier aspiration of fat

• Over 9 years of experience in Europe, Asia,

Middle East and South America

• More than 45 Clinical Studies

• Proven to perform technology

• Offers patients a more appealing option

that just liposuction alone

Smartlipo Clinical Indications

• Rupturing of adipocytes - localized fat

• Coagulation of small blood vessels

• Less bleeding, trauma, swelling, pain

and quicker recovery

• Promotes tissue coagulation resulting in

tissue tightening

• Ideal for areas of high flaccidity-neck, etc

• Useful tool for fibrous areas/corrections

Smartlipo Procedure

• Performed under local anesthesia

• Adjunct to liposuction

• Tumescent solution is applied to the area

(Lactate Ringers, epinephrine, lidocaine)

• Very small incisions made

• Fiber is threaded through cannula 1-2 mm

• Adipocytes are ruptured with laser

• Subdermal Layer is treated

for tissue tightening - through coagulation

• Aspiration is required for best results

Smartlipo Procedure

Reason #2

Bring Patients in the Door

Smartlipo Brand Name Recognition

Smartlipo voted #1

Best of All Aesthetic Procedures in

2010

for the third year in a row!*

*AmericanHealthandBeauty.com

Proven to Drive Patients to Your Practice

• Smartlipo is the most sought after procedure in the aesthetic industry

• Voted #1 Body Contouring Brand*

• Smartlipo has featured on over 400 local news stations and many big media outlets

• E! Television

• New York Times

• People Magazine

• 94% patient satisfaction rating

*by AmericanHealthandBeauty.com based on patient requests

Cynosure can help increase your referrals from the web

• Social Media

• Facebook and Twitter

initiatives

• Partnerships

• Liposuction.com

• The Patient’s Guide

• MD Connect

• Patient website

• Smartlipocynosure.com

Reason #3

Tissue Tightening - Treat areas that are difficult with traditional Liposuction alone

Results - Neck

Results - Abdomen

Results - Arms

Does it Last? 1 year Result

For Proven Tissue Tightening

• Blend 1064nm and 1320nm

• Produces a uniform thermal profile for proven tissue coagulation and tightening

• Tissue tightens 57% more than liposuction alone

• Evidence of new collagenproduction after Smartlipo treatments

Does Smartlipo MPX really tighten skin (tisssue)?

• Yes!

• 10-20% improved skin

area shrinkage

• Up to 57% improved

elasticity or tightening

index

• 4 studies by Drs.

DiBernardo, Katz and

Sasaki

4 Peer Review Studies to Prove It!

Tissue Tightening Video

Reason #4

Reduce complicationsLess touch ups

Less side effects

• Complication Rates

• Complication Rate of 0.93%

• Botox is 0.1-1%*

• Touch up Rates

• Touch up rate of 3.5 %

• Compared to 12% for standard

liposuction

• Local Anesthesia for less risk

• Study by Bruce Katz, MD and Jason McBean, MD

Clinical Evidence of Efficacy and Safety

* http://www.agemanagementoptimalwellness.com/age-management/botox-cosmetic 5.10.10

Reason #5

ThermaGuide Intelligent Delivery

Improved Patient Safety and More Control

Intelligent Delivery Systems Improving Clinical Outcomes

• New technologies make Smartlipo

Easier to Use

• SmartSense

• ThermaGuide

• Groundbreaking Thermal Sensing Products:

• Provide more precise and controlled body contouring

• Achieve a higher level of safety

• Best possible skin tightening results*

• Available only from Cynosure

*through tissue coagulation

Epidermal necrosis & collaginous change

0

1

20 30 40 50 60 70 80

Surface Temprature (oC)

Occu

ran

ce o

f n

ecro

sis

Epidermal necrosis &

collaginous change

ThermaGuide Technology Development

Clinical Temperature

Study-DiBenardoHandheld

Infrared

Thermometer

ThermaGuideSubdermal

Thermal Sensing

Clinical Implications of Temperature

Journal of Cosmetic

and Laser Therapy Study

DiBenardo

• Groundbreaking study is the 1st to

correlate subdermal temperature rise

with tissue damage

• Exceed these temperatures and cause

epidermal and dermal injury:

• Skin surface - 47ºC

• Tissue at 5mm deep - 50-55ºC

• Collagen changes found in tissue

heated, but not damaged

• Temperature for best skin tightening

determined

Epidermal necrosis & collaginous change

0

1

20 30 40 50 60 70 80

Surface Temprature (oC)

Occ

ura

nce

of

nec

rosi

s

Epidermal necrosis &

collaginous change

Surface Temperature

Yes

Necrosis

threshold

(47oC)

Surface temperature vs. Histological finding of

epidermal necrosis and collaginous change

No

ThermaGuide

• ThermaGuide is a temperature sensing cannula

• Continuously monitors subdermal tissue temperature

• Interacts with the Smartlipo MPX workstation

ThermaGuide

• ThermaGuide cannula contains a temperature sensor 1cm from the distal fiber tip

• Max cross section approximately 2 mm

Cannula

Heatshrink

Temp sensor

Kerf recess

ThermaGuide

• Smartlipo displays

temperature on the screen

• Laser energy delivered to

reach target temperature

• Safer and more uniform

treatment

• Adjust temperature -

recommendations for each

treatment area or type

ThermaGuide Case StudyDr. Stephen Mulholland

• Neck Treatment

• 50 yr. old woman

• Smartlipo Settings:

• 6W 1064nm/6W 1320nm

• ThermaGuide Settings:

• Low: 40ºC High: 45ºC

• ThermaGuide was used to determine endpoint

• Results:

• Consistent, safe subdermal and epidermal temperature of 40° C

• More precise and refined control of laser energy delivery achieved

while increasing patient safety

Reason #6

Smartlipo – more than just liposuction

Emerging Indications –Hyperhidrosis & Lipomoas

• Subdermal Nd-YAG Laser for Auxiliary

Hyperhydrosis

• Alberto Goldman M.D. and Uwe Wollina,

M.D.

• 17 Patients

• 88.% reported good-excellent results

• Treatment of Lipomas

• Eradication of fibrous lipomas, usually

excised

• Minimally invasive, no scarring, quick

recovery

Smartlifting Application

• SmartLifting: A Technological Innovation for Facial Rejuvenation

• Richard Gentile M. D.

• 200 Patients

• Benefits-Speed, less bleeding, skin tightening, downtime

New SmartLook Application

• Minimally invasive LaserFacialSculpting

• Tighten tissue (skin) subdermally

• Apply laser energy where it is more effective

• Reduce volume (only if needed)

• Accomplish with ThermaGuide – it’s safer and easier

SmartLook Results

• Excellent results

• Less Bruising and

bleeding

• Less Downtime (1-2

days)

• Addresses the jowl

area very well

SmartLook Results

Reason #7

Only Cynosure offers the fastest and most versatile laser system

Laser Lipolysis Redefined

New Smartlipo Triplex Laser

• 1440, 1320, 1064 nm wavelengths

• Smartlipo delivery system

• New look, GUI and display

• Most effective laser lipolysis

• SmartSense™ enabled

• Improved ThermaGuide™

New Smartlipo TriPlex

• Delivered by multiplex and intelligent delivery

• Smartlipo TriPlex now offers 3 wavelengths

• 1064nm

• 1320nm

• 1440nm

Constantly Redefining Laser Body Sculpting

6W

TriPlex

10W 12W 18W 20W

SmartSense

300 m

fiber

600 m

fiber

Blue handpiece ThermaGuide

30W 46W

11/07 11/095/0711/06 5/08

1000 m

fiber

MultiPlexing

40W, 24W, 15W

1064nm, 1320nm, 1440nm

5/09 01/11

New ThermaGuide

New RFID

fiber

Why add 1440nm?

• 1440nm has 40X greater

absorption in fatty tissue than

diode lasers (924nm and

980nm)

• Greater absorption =

50% faster treatments for

improved ROI

• Blend with 1064nm for

hemostasis

980nm Diode CW Treatment

15W treatment in actual human fatty tissue

Smartlipo TriPLex 1440 nm Treatment

15W treatment in actual human fatty tissue

Smartlipo TriPlex Specifications

System Type Nd:YAG

Individual Wavelength Options

Wavelength 1064nm 1320nm 1440nm

Pulse Width (Max) 500µs 1000µs 1000µs

Power Output Options 40W 24W 15W

Max Rep Rate 40Hz 40Hz 25Hz

Multiplexing Options

Wavelength 1064nm and 1320nm 1064nm and 1440nm

Pulse Width (Max) 500µs and 1000µs 500µs and 1000µs

Power Output Options 32W 20W

Max Rep Rate 40Hz 40 Hz and 25Hz

Aiming Beam Red

Electrical

Requirements

230 VAC/16A

Size (HxWxD) 37.4” x 19.7” x 25.6”

(95cm x 50cm x 65cm)

Weight 220 lbs (100kg)

Optimizing Your Treatments

• Recent clinical studies, demonstrates faster

treatment times and use of less energy

Data courtesy of Barry DiBernardo, MD

More Fat is Disrupted Using Less Energy with 1440nm

Heated Area Disrupted

Area

Subcutaneous fatty tissue

1 week after 4W 1440nm Rx

Less Power Need for a larger

disrupted area

Subcutaneous fatty tissue

1 week after 20W 1320nm Rx

Larger heated area more ideal for

tissue tightening

Heated Area Disrupted

area

Smartlipo - High Definition Results

TriPlex Means High-Def Capability

• 1440nm allows for

easier subdermal

release

• Treatment is faster-

required for a lengthy

procedure

• Adds another patient

population

Smartlipo Graphic User Interface

“Smarter” GUI

Features

• New Look and Feel

• 2X Larger display and font

New Angle

• Tracks Fiber Life with

RFID logic

Benefits

• Simpler Navigation

• Effortlessly read critical

parameters

• For safe, precise and

accurate treatment

New RFID Fiber Technology

• New Smartlipo TriPlex laser recognizes fiber

• How it works:

• RFID tag in fiber

• RFID reader inside laser

• 20 connects for enhanced safety, optimized energy delivery

• Sold Non-sterile 5 packs

• 600 and 1000 micron (orange, green)

Smartlipo TriPlex:

• Offers the right combination of wavelength for optimum results in a wide variety of patients• More effective laser lipolysis

• Proven tissue coagulation resulting in tightening

• Faster treatment time

• Less Downtime

• High-definition sculpting capabilities

• Continued Innovation

• Unmatched Delivery Systems

with ThermaGuide

• Added additional power and

wavelengths

• Larger Fibers

• Proven to Perform

• The most clinical studies

• 9 years of use Globally

• #1 Choice amongst patients

Cynosure has Continued to Define Future of Laser Body Sculpting

• Proven to be Profitable

• Brand Awareness

• Expanded Patient Base

• Treat New Applications

• Facial Treatments

• Corrections/Scar tissue

• Cellulite

• Elastosis/skin laxity

• Hyperhidrosis

Summary

• Smartlipo’s popular brand name provides

customers with a huge revenue making

opportunity

• Smartlipo TriPlex has become the standard of

care for laser lipolysis around the world

• Treat all patients body contouring concerns