PP-01974-001 Rev. 001 © 2018. Hologic, Inc. All rights reserved. Hologic, The Science of Sure, Pap+HPV Together and associated logos are trademarks and/or registered trademarks of Hologic, Inc. and/or its subsidiaries in the United States and/or other countries. This information is intended for medical professionals in the U.S. and other markets and is not intended as a product solicitation or promotion where such activities are prohibited. Because Hologic materials are distributed through websites, eBroadcasts and tradeshows, it is not always possible to control where such materials appear. For specific information on what products are available for sale in a particular country, please contact your local Hologic representative or write to diagnostic.solutions@hologic.com.

* As many as 93% of cervical cancers could be prevented by screening and HPV vaccination.2

References: 1. American Cancer Society. Cancer Facts & Figures 2017. Atlanta, GA: American Cancer Society; 2017. 2. CDC. Cervical Cancer is Preventable. https://www.cdc.gov/vitalsigns/cervical-cancer/index.html. CDC website. Updated November 5, 2014. Accessed February 7, 2018. 3. Benard VB et al. Vital signs: cervical cancer incidence, mortality, and screening – United States, 2017-2012. Morbidity and Mortality Weekly Report. 2014;63: 1. 4. Chesson HW et al. The estimated lifetime probability of acquiring human papillomavirus in the United States. Sexually Transmitted Diseases. 2014;41(11): 660. 5. Blatt, et al. Comparison of cervical cancer screening results among 256,648 women in multiple clinical practices. 2015;123(5):282-8. Doi:10.1002/cncy.21544. (Study included ThinPrep®, SurePath, Hybrid Capture 2 Assay) 6. Saslow D, Solomon D, Lawson HW, et al. American Cancer Society, American Society for Colposcopy and Cervical Pathology, and American Society for Clinical Pathology screening guidelines for the prevention and early detection of cervical cancer. CA Cancer J Clin. 2012;62(3):147-172. 7. CDC. Genital HPV Infection – CDC Fact Sheet. http://www. cdc.gov/std/hpv/hpv-factsheet-march-2014-press.pdf. Published 2014. February 7, 2018.

WHAT DOES YOUR HEALTHCARE PROVIDER NEED TO KNOW AT YOUR ANNUAL EXAM?☐ The date of your last period

☐ Whether your periods come regularly, how long they last

and how heavy they are

☐ If you’ve ever had an abnormal Pap test

☐ The date of your last mammogram

☐ The date of your last colonoscopy

☐ Whether you feel pain during intercourse

☐ Any drastic weight changes

☐ Any medications, including non-prescription drugs

☐ Any family history of cancer, heart disease or diabetes

☐ Recent changes in skin or hair loss

☐ Issues with bladder control

HOW CAN YOU PROTECT YOUR CERVICAL HEALTH?Start by talking with your healthcare provider. If you are 30 to 65 years old, a Pap test in combination with an HPV test provides a more accurate and reliable cervical cancer screening result.5

HOW BEST TO PREPARE FOR YOUR ANNUAL EXAM:⊲ Avoid vaginal medication,

personal lubricants, vaginal contraceptives and douches for 48 hours before your appointment.

⊲ Refrain from sexual intercourse for 48 hours before your appointment.

⊲ Drink plenty of water the day of your appointment. You may need to give a urine sample.

⊲ Schedule your appointment on a day when you will not have your period.

✓✓

✓✓✓✓✓✓✓✓✓

5 MYTHS ABOUT HPV AND CERVICAL CANCER

MYTH: If I am getting screened for cervical cancer I will have a co-pay or deductible.

TRUTH: Cervical cancer testing is currently covered under the Affordable Care Act.* This means you may not be responsible for a co-pay, deductible or other out-of-pocket costs. If you don’t have health insurance, there are clinics across the United States that provide testing at low or no cost. Women, no matter their circumstances, can and should get tested.

* Coverage may not be available to all patients. Please consult your health plan for coverage.

MYTH: If I feel healthy, I don’t need to worry about cervical cancer.

TRUTH: Cervical cancer can be present without any symptoms. In fact, most people infected with HPV – the major cause of cervical cancer – have no symptoms.7

MYTH: If I have HPV, I will get cervical cancer.

TRUTH: Most of the time, HPV infections go away on their own without causing any health problems. Some HPV types do not go away and cause cells to change. Left untreated, some infections cause cervical cancer.7

MYTH: I am in a long-term monogamous relationship, therefore I do not need to get screened for cervical cancer anymore.

TRUTH: Anyone who is sexually active can get HPV, even if you have had sex with only one person. You can also develop an HPV infection years after you had sex with someone who is infected, making it hard to know who infected you.7

MYTH: My Pap tests have been negative recently, so I do not have to worry about testing for a while.

TRUTH: A normal Pap result means no cell changes were found on your cervix. This is good news. You still need to get Pap tests in the future, however, as it can take decades for cervical cancer to develop. New cell changes can still form on your cervix after a normal result.7

Visit CHANGETHISSTAT.COM to learn more about the importance of cervical cancer screening.

THE CHANGE STARTS WITH YOU

EVERY2 HOURS1 WOMANDIES OFCERVICALCANCER1

Erin AndrewsSports Broadcaster, TV Personality & Cervical Cancer Survivor

STILL UNSURE ABOUT GETTING TESTED?

WHY PAP+HPV TOGETHER?

The two tests work in tandem.

There’s something women need to talk about: HPV. The truth is, it’s a common infection — the majority of women have it at some point.4 But certain strains of HPV can actually cause cervical cancer. So why not test for that, too?

At its core, Pap+HPV Together is actually 2 tests in one. It’s simple — your doctor takes a single sample, and both a Pap test and an HPV test are ordered. Together, they identify more cervical precancer and cancer than either could on its own.5

95% of cervical cancers are detected with Pap+HPV Together.5

For women over 30, the best way to prevent cervical cancer is to see your doctor and get tested with Pap+HPV Together.5

95% OF CERVICAL CANCERS ARE DETECTED BY TESTING WITH PAP+HPV TOGETHER.5

EVERY HOUR, 1 WOMAN IN THE U.S. IS DIAGNOSED WITH

CERVICAL CANCER.1

ONE THIRD OF U.S. WOMEN DIAGNOSED WITH CERVICAL

CANCER DIE.1

MORE THAN 1/2 OF NEW CERVICAL CANCER CASES OCCUR IN WOMEN WHO HAVE NEVER OR RARELY BEEN TESTED.3

ABOUT 8 OUT OF 10 WOMEN IN THE U.S. WILL CONTRACT THE VIRUS THAT

CAN CAUSE CERVICAL CANCER.4

AGES 21-29

You should have a Pap test first. If your Pap test result is unclear, your provider may perform an HPV test.6

AGES 30-65

Your provider may routinely test with Pap+HPV Together.6

Ask your doctor today to get tested and visit CHANGETHISSTAT.COM for more information.

THE CHANGE STARTS WITH YOU

GETTING TESTED SAVED MY LIFE

As a survivor of cervical cancer, I think it’s time we got something straight. It’s not just a treatable disease. It’s preventable.2* Through testing with Pap+HPV Together, healthcare providers can identify signs of cervical cancer and treat them before they become a problem.3 It all starts with a simple, annual exam.

So what does this all mean? That 2 hours from now, we’ll lose another woman to a preventable disease.1,2 We can’t stand on the sidelines and let it happen anymore.

Together, we can reduce the number of women dying of cervical cancer. But to do that, we all need to commit to testing with Pap+HPV Together. I’m in. Are you?

–Erin