4.topical astringents
TRANSCRIPT
Pankaj Kusum Ramdas KhuspeM. Pharmacy (Pharmaceutics)
“Brings about protein precipitation.”
E.g.: Alum
Uses
For Styptic action
Anti inflammatory
Anti perspirant
Anti microbial
To remove unwanted skin
Alum
KAlSO4 .12H2O
MOP:1. From Alunite or bauxite
2. By mixing conc. potassium sulphate to aluminum sulphate
Physical Properties:
• Colorless granular crystalline powder
• Odourless
• Sweet astringent taste
• soluble in water
• Soluble in glycerin
• Insoluble in alcohol
• Aqueous solution is acidic in nature
Uses
• Topical agent
• Astringents
• Preparation of toxoids
• Antiseptics
• Local styptic action
Storage
“ It should be stored in well closed container at a cool
place.”
Zinc sulphate
ZnSO4MOP:1) By heating zinc sulphate in air
ZnS + 2O2 ZnSO4
2) Mixing zinc with sulphuric acidZn + H2SO4 ZnSO4 + H2
Physical Properties:
• Colorless powder• Odorless• Astringent taste• Very soluble in water• Very soluble in glycerin• Insoluble in alcohol• Aqueous solution is acidic in nature
Chemical Properties
When it is strongly heated it decomposes
Uses
• Topical agent• Astringents• Mild germicidal• Emetic• Local styptic action• Preparation of bandages and adhesive
tapes
Storage
“ It should be stored in well closed container at a cool
place.”