Curriculum Vitae

Young Kwok, M.D.Associate Professor

Department of Radiation OncologyUniversity of Maryland School of Medicine

Date: April 3, 2014

Contact InformationYoung Kwok, MDDept of Radiation OncologyUniversity of Maryland School of Medicine22 South Greene St.Baltimore, MD 21201 USAEmail: ykwok@umm.eduOffice: (410) 328-9134Fax: (410) 328-5279

Education1995 B.A. Psychology, Johns Hopkins University, Baltimore, MD

Departmental and General Honors1999 M.D. Albert Einstein College of Medicine, Bronx, NY

Post Graduate Education and Training2000 Internship Internal Medicine, Beth Israel Medical Center, New York, NY2004 Residency Radiation Oncology, University of Maryland Medical Center, Baltimore, MD

Certifications2006 American Board of Radiology

Medical Licensures2004 Maryland State License, active2004 Michigan State License, inactive

Employment HistoryAcademic Appointment2004-2011 Assistant Professor, Department of Radiation Oncology, UMSOM2011-present Associate Professor, Department of Radiation Oncology, UMSOM

Clinical Privileges2004-Present University of Maryland Medical Center, Baltimore, MD2004-Present Baltimore VA Medical Center, Baltimore, MD2004-2010 Maryland General Hospital, Baltimore, MD2004-2010 Montgomery General Hospital, Olney, MD2004-Present Howard County General Hospital, Columbia, MD2008-Present Baltimore-Washington Medical Center, Glen Burnie, MD

Professional Memberships2000-2004 American College of Radiation Oncology

Young Kwok, M.D.

2000-2004 American College of Radiology2000-Present American Society for Therapeutic Radiology and Oncology2003-Present American Brachytherapy Society2004-Present American Society of Clinical Oncology2004-Present Radiation Therapy Oncology Group2004-2011 Cancer and Leukemia Group B (CALGB)2009-Present Children’s Oncology Group2011-Present Alliance for Clinical Trials in Oncology (merged group of CALGB, NCCTG,

ACOSOG)

Honors and AwardsUndergraduate1991-1995 Full Academic Scholarship1991-1995 Academic Dean’s List1995 General and Departmental Honors

Medical School1998 Travel Grant: American Society of Hematology, Miami Beach, FL

Residency2002 Roentgen Resident/Fellow Research Award: Radiologic Society of North America,

Chicago, IL2003 Travel Grant: Radiation Therapy Oncology Group Meeting, New Orleans, LA2003-2004 Chief Resident

Assistant Professor2006 Teacher of the Year: Association of Residents in Radiation Oncology.2008 Clinical Scholars Award: Cancer and Leukemia Group B, Chicago, IL

Associate Professor2012 Outstanding Reviewer of 2012, International Journal of Radiation Oncology, Biology,

Physics

Clinical ActivitiesClinical ExpertiseGenito-urinary malignanciesCentral nervous system malignanciesPediatric malignanciesLymphomas and leukemias

Technical ExpertiseIntensity-Modulated Radiation Therapy (IMRT)Image-Guided Radiation Therapy (IGRT)Stereotactic Radiosurgery (SRS), Gamma-knife, Trilogy, TruebeamFractionated Stereotactic Radiation Therapy (FSRT)Stereotactic Body Radiation Therapy (SBRT)Interstitial/Intracavitary Brachytherapy

Scope of Clinical PracticeLarge academic medical center

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Young Kwok, M.D.

250-300 patient consultations per year150-180 patients treated per yearClinical Duties: 4 days/week, 12 months/year

Development of Clinical Programs2004-Present Developed a high-risk prostate cancer program

Contribute the vast majority of patients to the Gamma Knife program2004-Present Developed an active clinical trial programs in CNS, GU and Pediatric.2009-Present Developed a pediatric oncology collaborative program with Children’s National Medical

Center, Washington DC

Clinical TrialsUniversity of Maryland Medical Center Protocols2005 – 2006 PI

Retrospective Chart Review of Patients who have undergone Permanent Interstitial Prostate Brachytherapy to Study the Correlation Between Pre-

Operative CT Scan Beams-Eye-View Prostate Volume with Real-Time Intraoperative Ultrasound Prostate Volumes

2005 - 2006 PIGCC 0501: Retrospective Review of stereotactic Radiosurgery Treatments of

Benign, Primary and Metastatic Lesions: A University of Maryland Experience.

2006 - 2011 Co-PI (PI: David Eisenman, MD)Gamma Knife for Acoustic NeuromaRole: Helped design study. Enroll patients. Will assist in analyzing and

publishing results.

2006 - present PIGCC 0605: Phase II Study Evaluating Bone Marrow-Sparing, Image-Guided Pelvic Intensity-Modulated Radiotherapy (IMRT) with Cesium-131 Brachytherapy Boost, Adjuvant Chemotherapy, and Long-Term Hormonal Ablation in Patients with High Risk, Non-Metastatic Prostate Cancer.”

2013 - present PIGCC 1224: Phase II Trial of Low-Dose Whole Brain Radiotherapy with Concurrent Temozolomide and Adjuvant Temozolomide in Patients with Newly-Diagnosed Glioblastoma Multiforme

2013 - present PIGCC 1328: Retrospective Analysis of Salvage External Radiation Therapy in Patients with Recurrent Prostate Cancer after Brachytherapy

Principle Investigator of National/International Protocols2013 - present Co-Chair, Alliance (CALGB)

RTOG 1115: Phase III Trial of Dose Escalated Radiation Therapy and Standard Androgen Deprivation Therapy (ADT) with a GnRH Agonist vs. Dose Escalated Radiation Therapy and Enhanced ADT with a GnRH Agonist and TAK-700 for Men with High Risk Prostate

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Institutional Principle Investigator of National/International Protocols2006 - 2009 RTOG 0320: A Phase III Trial Comparing Whole Brain Radiation and

Stereotactic Radiosurgery Alone Versus with Temozolomide or Erlotinib in Patients with Non Small Cell Lung Cancer and 1-3 Brain Metastases

2007 - 2009 RTOG 0415: A Phase III Randomized Study of Hypofractionated 3D-CRT/IMRT versus Conventionally fractionated 3D-CRT/IMRT in Patients with Favorable-risk Prostate Cancer.

2005 - 2009 RTOG 0424: A Phase II Study of a Temozolomide-Based Chemoradiotherapy Regimen for High Risk Low-Grade Gliomas

2008 - present RTOG 0526: A Prospective Phase II Trial of Transperineal Ultrasound-Guided Brachytherapy for Locally Recurrent Prostate Adenocarcinoma Following External Beam Radiotherapy

2008 - present RTOG 0534: A Phase III Trial of Short Term Androgen Deprivation with Pelvic Lymph Node or Prostate Bed Only Radiotherapy (SPORT) in Prostate Cancer Patients with a Rising PSA after Radical Prostatectomy

2008 - 2010 RTOG 0614: A Randomized, Phase III, Double-Blind, Placebo-Controlled Trial of Memantine for Prevention of Cognitive Dysfunction in Patients Receiving Whole-Brain Radiotherapy

2008 - 2009 RTOG 0513: A Phase I/II Trial of Temozolomide, Motexafin Gadolinium, and 60 Gy Fractionated Radiation for Newly Diagnosed Supratentorial Glioblastoma Multiforme

2008 - 2010 RTOG 0621: Adjuvant 3DCRT/IMRT in Combination with Androgen Suppression and Docetaxel for High Risk Prostate Cancer Patients Post-Prostatectomy: A Phase II Trial

2009 - 2011 RTOG 0825: Phase III Double-Blind Placebo-Controlled Trial of Conventional Concurrent Chemoradiation and Adjuvant Temozolomide plus Bevacizumab versus Conventional Concurrent Chemoradiation and Adjuvant Temozolomide in Patients with Newly Diagnosed Glioblastoma

2009 - 2012 RTOG 0539: Phase II Trial of Observation for Low-Risk Meningiomas and of Radiotherapy for Intermediate and High-Risk Meningiomas

2010 - present RTOG 0815: Phase III Prospective Randomized Trial of Dose-Escalated Radiotherapy with or without Short-Term Androgen Deprivation Therapy for Patients with Intermediated-Risk Prostate Cancer.

2010 - 2012 RTOG 0831: A Randomized, Double-Blinded, Placebo-Controlled Phase III Trial to Evaluate the Effectiveness of a Phosphodiesterase 5 Inhibitor, Tadalafil, in Prevention of Erectile Dysfunction in Patients Treated with Radiotherapy for Prostate Cancer.

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2011 - present RTOG 0929: A Randomized Phase I/II Study of ABT-888 in Combination With Temozolomide in Recurrent (Temozolomide Resistant) Glioblastoma

2011 - present RTOG 0924: Androgen Deprivation Therapy and High Dose Radiotherapy With or Without Whole-Pelvic Radiotherapy in Unfavorable Intermediate or Favorable High Risk Prostate Cancer: A Phase III Randomized Trial

2011 – present RTOG 0938: A Randomized Phase II Trial Of Hypofractionated Radiotherapy For Favorable Risk Prostate 

2013 - present RTOG 0913: Phase I/II Trial of Concurrent RAD001 (Everolimus) With Temozolomide/Radiation Followed by Adjuvant RAD001/Temozolomide in Newly Diagnosed Glioblastoma

2013 - present RTOG 1205: Randomized Phase II Trial of Concurrent Bevacizumab and Re-Irradiation Versus Bevacizumab Alone as Treatment for Recurrent Glioblastoma

Institutional Co-Principle Investigator of National/International Protocols2002 - 2008 RTOG 0126: A Phase III Randomized Study of High Dose 3D-CRT/IMRT

versus Standard Dose 3D-CRT/IMRT in Patients Treated for Localized Prostate Cancer.

2003 - present RTOG 0232: A Phase III Study Comparing Combined External Beam Radiation and Transperineal Interstitial Permanent Brachytherapy with Brachytherapy Alone for Selected Patients with Intermediate Risk Prostatic Carcinoma.

Administrative ServiceInstitutional (UMSOM)2004-Present Tumor Boards

2004-Present GU Tumor Board (Leader/Coordinator since March 2007)2004-Present Solid Tumor Board2004-Present CNS Tumor Board2004-Present Lymphoma Tumor Board2004-Present Pediatric Tumor Board2007-2008 Base of Skull Tumor Board2007-2009 Head and Neck Tumor Board

2004-Present Committees2005-2009 Cancer Review Committee2005-2011 Technology Review Committee2010-2013 Radiation Oncology IT Committee2010-2011 University of Maryland Dosimetry School Curriculum Committee2010-Present University of Maryland Dosimetry School Advisory Committee2011-Present Brachytherapy Committee

2004-Present Internal Residency/Fellowship Review2004 Urology2005 Interventional Cardiology

2004-Present UMSOM Admissions—Applicant Interviews, 10-15 per year2004-Present Radiation Oncology Electronic Library2005-Present Institutional Review Board, IRB Panel #4 (committee #1 starting 2013)2007-Present Ask the Expert ( www.umm.edu website)

2007-Present Spine-directed Oncology Program.

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http://www.umgcc.org/brain_tumor_center/spine-directed-oncology.htm2009-Present Gamma Knife Center

http://www.umm.edu/gammaknife/index.htm2010-Present Prostate Seed Implant

http://www.umgcc.org/gu_program/psi.htm

2008 Department of Radiation Oncology Research Retreat (April 2, 2008)Coordinated a research retreat, which included the subdivisions of physics, biology, and clinical faculty, with the following objectives:

1. To identify barriers and limitations that prevent effective clinical/translational research

2. To identify strategies to optimize effective interdepartmental research collaboration3. To identify strategies to optimize effective inter-institutional research collaboration

2008-2009 Acting Director of Clinical ResearchDepartment of Radiation Oncology, University of Maryland Medical Center

2009-2012 Associate Director of Clinical ResearchDepartment of Radiation Oncology, University of Maryland Medical Center

2009-2011 Cancer Interest Group2011-2013 Univ of Maryland-Baltimore/University of Maryland-College Park annual seed

competition, reviewer2012 Department of Radiation Oncology, Practice Guidelines

Jan 17, 2012 CNS CancersMar 27, 2012 LymphomasJune 5, 2012 Gamma Knife Stereotactic Radiosurgery

2013 Associate Director of ResidencyDepartment of Radiation Oncology, University of Maryland Medical Center

2013 Director of Medical Student RotationsDepartment of Radiation Oncology, University of Maryland Medical Center

2013 Department of Radiation Oncology--Appointments, Promotions, Tenure Committee 2013 Nilesh Mistry, PhD (Instructor to Assistant Professor)

Mariana Guerrero, PhD (Clinical Assistant to Clinical Associate Professor)Wei Lu, PhD (Assistant to Associate Professor)Yildirim Mutaf, PhD (Assistant to Associate Professor)Warren D’Souza, PhD (Associate Professor to Professor)

2014 Hao (Howard) Zhang, PhD (Instructor to Assistant Professor)

Local/Regional2004-2007 Cancer Committee, Baltimore VA Medical Center, Baltimore, MD2008-2009 White Oak Seminar Series: Coordinated a series of Radiation Oncology

presentations at the FDA: Center for Devices and Radiological Health—The Federal Research Center @ White Oak, Silver Springs, MDMarch 26, 2008 Speaker: Young Kwok, M.D.

Topic: Recent Advances in Radiation OncologyApril 30, 2008 Speaker: Michael Garofalo, M.D.

Topic: Liver-directed TherapyMay 28, 2008 Speaker: Majid Mohiuddin, M.D.

Topic: Recent Advances in Breast Cancer

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Young Kwok, M.D.

August 27, 2008 Speaker: William Regine, M.D.Topic: Brain Metastases Management

September 24, 2008 Speaker: Anil Dhople, M.D.Topic: Stereotactic Body Radiation Therapy

February 25, 2009 Speaker: Pradip Amin, M.D.Topic: Brachytherapy

2009-Present Pediatric Tumor Boards, Children’s National Medical Center (Washington, DC)2009-Present Pediatric Solid Tumor Board2009-Present Pediatric CNS Tumor Board

National/International2011-Present Editorial Board, International Journals

2011-present The World Scientific Journal

2003-Present Ad Hoc Reviewer, International Journals2003-present Technology in Cancer Research and Treatment2004-present American Journal of Clinical Oncology2005-present International Journal of Radiation Oncology Biology Physics2005-present Journal of Clinical Oncology2006-present Spinal Cord2007-present International Journal for Quality in Health Care2007-present The Lancet Oncology2007-present Cancer2008-present Lung Cancer2008-present Molecular Cancer Therapeutics2011-present Mayo Clinic Proceedings

2005-11 Genito-urinary & Radiation Oncology Committees, Cancer and LeukemiaGroup B (CALGB), Chicago, IlGenito-urinary CommitteeRadiation Oncology Committee

2006-2007 University of Maryland Annual Radiobiology, Physics Review Course: Annual review course for the Radiation Oncology Written Board Exam attended by a majority of residents throughout the country.April 28-30, 2006 Co-coordinatorMay 3-6, 2007 Co-coordinator

2007-present American Board of Radiology (Radiation Oncology)2007 Genito-urinary written board examination writer2008 Genito-urinary written board examination writer

2011-Present Alliance for Clinical Trials in Oncology (merged group of CALGB, NCCTG, ACOSOG)Genito-urinary CommitteeRadiation Oncology Committee

Teaching ServiceMedical School Lectures (UMSOM, 15-20 students)2001-11 Discussion Group Facilitator for second year medical school small group in

oncology, one 2 hour class per year

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Clinical Teaching Duties (University of Maryland Medical Center)2004-Present Attending Physician, inpatient/outpatient consults, outpatient clinic

1 resident, 10 hours/day, 4 days/week, 10-12 months/year

Graduate School Lectures (University of Maryland, Baltimore, 10-15 students)2008 GPIL 665 course - Special Topics in Cancer Biology

Contemporary Management of Glioblastoma. 1.5 hr lecture--October 27, 2008Course Director: Feyruz Rassool, Ph.D.Graduate Student Mentees (2hr/week for 2 weeks for each student):

Dipika Germani, Final Project: Alternatives strategies in overcoming imatinib resistance in chronic myeloid leukemia patients.Amanda Graner, Final Project: The Role of the t(4; 14)(p16; q32) translocation in multiple myeloma

2009 GPIL 665 course - Special Topics in Cancer BiologyCNS Tumor: Clinical Management. 1.5 hr lecture--October 26, 2009Course Director: Feyruz Rassool, Ph.D.

2010 GPIL 665 course - Special Topics in Cancer BiologyCNS Tumor: Clinical Management. 1.5 hr lecture—October 29, 2010Course Director: Feyruz Rassool, Ph.D.

2011 GPIL 665 course - Special Topics in Cancer BiologyCNS Tumor: Clinical Management. 1.5 hr lecture—November 14, 2011Course Director: Feyruz Rassool, Ph.D.

2012 GPIL 665 course - Special Topics in Cancer BiologyCNS Tumor: Clinical Management. 1.5 hr lecture—November 26, 2012Course Director: Feyruz Rassool, Ph.D.

2013 GPIL 665 course - Special Topics in Cancer BiologyCNS Tumor: Clinical Management. 1.5 hr lecture—November 25, 2013Course Director: Feyruz Rassool, Ph.D.

Wrote and graded exams

Ph.D. Dissertation Committee2008-2012 (2 hour/month)

Candidate: Nneka Onwudiwe, University of Maryland School of PharmacyTitle: Breast Conserving Surgery: Event Free Survival and Costs Subsequent to Radiation TherapyAdvisors: Ebere Onukwugha, Ph.D., C Daniel Mullins, Ph.D., Young Kwok, M.D.Proposal Defense: May, 2009Ph.D. Thesis Defense: March 2012

Resident Lectures, Department of Radiation Oncology (1 hour, 10-15 Residents and Students)April 20, 2005 Pediatric MedulloblastomaJune 12, 2007 Metastatic Spinal Cord CompressionNov 20, 2007 MedulloblastomaDec 4, 2007 Predictors of Outcome in Prostate Cancer

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Jan 2, 2008 Jeopardy: Genito-urinary CancersOct 7, 2008 Contemporary Management of Non-metastatic Prostate CancerOct 28, 2008 Jeopardy: Genito-urinary CancersApril 22, 2009 Radiation Sensitizers in MetastasisApril 29, 2009 Jeopardy: Central Nervous SystemOct 7, 2009 High-Risk Prostate CancerMarch 17, 2010 Pediatric EpendymomaOctober 5, 2010 “Tie Breakers” in Prostate CancerMay 4, 2011 Pediatric Hodgkin’s Disease—Late Morbidity and MortalityMay 11, 2011 Alternative Dose Delivery SystemsMarch 28, 2012 Post-operative Radiation Therapy for Prostate CancerMay 9, 2012 Alternative Dose Delivery SystemsMarch 20, 2013 Pediatric JeopardyMay 8, 2013 Alternative Dose Delivery SystemsSept 19, 2013 Post-Prostatectomy Radiation Therapy

University of Maryland Dosimetry School Lectures (1 hour, 2 dosimetry students)October 25, 2004 CNS Dosimetry-Treatment PlanningApril 23, 2008 CNS TumorsNovember 5, 2008 Base of Skull Tumors INovember 12, 2008 Base of Skull Tumors IIMarch 17, 2010 CNS–Glioblastoma MultiformeApril 20, 2011 CNS–Glioblastoma MultiformeFebruary 7, 2013 CNS–Glioblastoma MultiformeFebruary 11, 2013 GU-BrachytherapyMarch 11, 2013 Prostate Cancer

Resident Mock Oral Preparatory Exams, Department of Radiation Oncology (1 hour, exam/feedback)Sept 21, 2005 Genito-urinary. Anil Dhople M.D.Oct 24, 2006 Genito-urinary. Todd Flannery M.D.Jan 17, 2007 Central Nervous System. Todd Flannery M.D.Nov 28, 2007 Genito-urinary. Ashish Patel M.D.Jan 21, 2010 Central Nervous System, Geoffrey Neuner, M.D.April 28, 2010 Central Nervous System/Pediatrics, Ashish Patel M.D.April 28, 2010 Central Nervous System/Pediatrics, Ali Mirmiran M.D.October 25, 2010 Genito-urinary, Usama Mahmood, M.D.April 27, 2011 Central Nervous System/Pediatrics

Navesh Sharma, M.D.Russell Hales, M.D. (Johns Hopkins)Kristen Redmon, M.D. (Johns Hopkins)Susannah Yovino, M.D. (Johns Hopkins)

May 4, 2011 Central Nervous System/Pediatrics, Genito-urinaryNavesh Sharma, M.D.Matthew Koshy, M.D.Kristen Redmon, M.D. (Johns Hopkins)

April 9, 2012 Central Nervous System/Pediatrics, Sarah Grabowski, M.D.May 11, 2012 Central Nervous System/Pediatrics, Genito-urinary

Geoffrey Neuner, M.D. (GBMC)

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Usama Mahmood, M.D. (MD Anderson Cancer Center)Randi Cohen, M.D.

June 4, 2012 Genito-urinary, Grace Kim, M.D.June 13, 2012 Central Nervous System/Genito-urinary, Zain Husain, M.D.Oct 3, 2012 Central Nervous System/Genito-urinary, Elizabeth Nichols, M.D.April 19, 2013 Central Nervous System/Pediatrics, Genito-urinary

Grace Kim, M.D. (Duke)Zain Husain, M.D. (Yale)Lara Bonner Millar, M.D. (Eastern Virginia)

May 1, 2013 Genito-urinary, Benjamin Laser, M.D.

Student Research Sponsorships/Mentorships (2 hours/week)2002-2003 Stephen Ronson, MS IV (University of Maryland School of Medicine)

Topic: Incidence and temporal pattern of hematuria and proteinuria in men treated with permanent interstitial prostate brachytherapy.Results: Presented at the American Radium Society, Houston, Tx, April 2003. Matched residency program in Radiation Oncology at Loma Linda Hospital, CA.

2003-2004 Neeraja Murali, BA (University of Maryland College Park)Topic: Long-term Results of Gamma Knife Stereotactic Radiosurgery for Non-functioning Pituitary Adenomas.Results: Presented at the American Society of Therapeutic Radiology and Oncology, Atlanta,

Ga October 2004. Entered graduate program in Epidemiology at Emory University, GA.

2003-2004 Susannah Yovino, MS IV (University of Maryland School of Medicine)Topic: Preoperative Anemia is Associated with Decreased Survival in Patients with Stage I and II Non-Small-Cell Lung Cancer Treated with Surgery.Results: Presented at the American Society of Therapeutic Radiology and Oncology, Atlanta,

Ga October 2004 Manuscript published in International Journal of Radiation Oncology Biology

Physics, 2005. Matched residency program in Radiation Oncology at University of Maryland School

of Medicine, MD.

2005-2007 Owen Thomas, MS III (University of Maryland School of Medicine)Topic: Long-term outcome of Gamma-Knife stereotactic radiosurgery for brain metastasis from radio-resistant tumors (melanoma, sarcoma, renal-cell carcinoma).Results: Presented at the Radiological Society of North America, Chicago, Il, November 2006 Matched in residency program in Radiation Oncology at Johns Hopkins Hospital,

MD

2005-2007 Lara Bonner, MS III (University of Maryland School of Medicine)Topic: Hematuria and Proteinuria in men treated with prostate brachytherapy.Results: Matched in residency program in Radiation Oncology at University of

Pennsylvania Hospital, PA

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2006-2007 Elizabeth Nichols, MS III (University of Maryland School of Medicine)Topic: Long-term outcome of patients with vestibular schwannoma treated with gammaKnife stereotactic radiosurgery.Results: Matched in residency program in Radiation Oncology at University of Maryland

Medical Center, MD

2009-2010 Tejan Diwanji, MS ITopic: Long-term outcome of multiple sclerosis patients with trigeminal neuralgia treated with Gamma-Knife stereotactic radiosurgery.Results: Summer Fellowship Award in Radiation Oncology ($2500). Department of Radiation

Oncology, University of Maryland School of Medicine Presented at the American Society of Therapeutic Radiology and Oncology, San

Diego, Ca October 2010

2009-2010 Sonu Bassi, Severn High School StudentTopic: Long-Term Results of a Prospective, Phase II Study of Long-term Androgen Ablation,Pelvic Radiotherapy, Brachytherapy Boost and Adjuvant Docetaxel in Patients with High-Risk Prostate CancerResults: Manuscript accepted to the International Journal of Radiation Oncology Biology

Physics, 2010. Early admission to Johns Hopkins University

2010-present Andrew Saltos, MS IIITopic: Outcomes of AVM patients treated with Gamma Knife.Results: Abstract accepted to the American Society for Radiation Oncology, 2011 annual

meeting. Manuscript published in Journal of Neurosurgery, 2012

2011-2012 Kevin Quinn, MS ITopic: Neurocognitive Function in Long-Term Survivors of Whole Brain RadiationResults: American Brain Tumor Association Medical School Summer Fellowship ($3000).

Department of Radiation Oncology, University of Maryland School of Medicine.

2012-present Moshe Meister, MS ITopic: High-Risk Prostate Cancer, Salvage therapy for Brachytherapy FailuresResults: Oral Presentation, American Society for Radiation Oncology, 2013 annual meeting Department of Radiation Oncology Summer Research Fellowship 2013 Submitted abstract for American Society for Radiation Oncology, 2014 annual

meeting

2012-present Matthew Ferris, MS IIITopic: High-Risk Prostate Cancer, Preliminary Results of GCC 0605Results: Oral Presentation, American Society for Radiation Oncology, 2013 annual meeting

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Matched for Radiation Oncology at Emory University

2013-present Shivum Kumar, High School StudentTopic: Proton Beam Therapy in Pediatric Patients: Photon vs Protons

Radiation Oncology Resident Research Sponsorships/Mentorships, Department of Radiation Oncology (2 hours/week)2003-2004 Pinaki Dutta, MD (University of Pennsylvania Hospital)

Topic: Comparison of Repeat GK-SRS for Refractory or Recurrent Trigeminal Neuralgia: Does Dose Matter?Results: Presented at the American Society of Therapeutic Radiology and Oncology, Atlanta,

Ga, October 2004.

2004-2005 Anil Dhople, MDTopic: Evaluation of Efficacy and Quality of Life in Patients with Atypical Facial Pain Treated with Gamma-Knife Stereotactic Radiosurgery.Results: Presented at the American Society of Therapeutic Radiology and Oncology, Denver,

Co, October 2005 Manuscript published. International Journal of Radiation Oncology Biology Physics,

2006.

2005-2006 Shilpen Patel, MDTopic: Evaluating the influence of dose-rate on outcome with gamma-knife stereotacticradiosurgery in the treatment of trigeminal neuralgia.Results: Presented at the American Society of Therapeutic Radiology and Oncology, Denver,

Co. October 2005.

2005-2006 Susannah Yovino, MDTopic: Long-term outcome of breast cancer patients treated with Gamma-Knife stereotactic radiosurgery for brain metastasisResults: Presented at the Radiologic Society of North America, Chicago 2006.

2005-2006 Kathleen Settle, MDTopic: A Volumetric Study of Needle’s Eye View CT scan in Predicting Pubic Arch interference and Intra-operative Prostate Volume in Men Undergoing Permanent Interstitial ProstateBrachytherapy.

2005-2007 Anil Dhople, MDTopic: Long-term outcome of Gamma-Knife stereotactic radiosurgery for brain metastasis from radio-resistant tumors (melanoma, sarcoma, renal-cell carcinoma).Results: Presented at the Radiological Society of North America, Chicago, Il, November 2006

2005-2007 Todd Flannery, MD

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Topic: The Impact of Definitive Thoracic Management on Long-Term Survival in Patients with Synchronous, Solitary Brain Metastases from Non-Small Cell Lung Cancer Treated with Stereotactic Radiosurgery.Results: Presented at the American Society of Therapeutic Radiology and Oncology,

Philadelphia, PA 2006 Manuscript published International Journal of Radiation Oncology Biology Physics,

2008.

2005-2008 Todd Flannery, MDTopic: Long-term Results of Intermediate and High-Risk Prostate Cancer Patients Treated with Prostate BrachytherapyResults: Presented at the American Brachytherapy Society, Philadelphia, PA, May 2006 Resident Travel Award for Dr. Flannery

2007-2008 Usama Mahmood, MDTopic: Dosimetric Analysis of Cesium-131 Brachytherapy.Results: Presented at the American Brachytherapy Society, Boston, MA, May 2008.

2007-2009 Ali Mirmiran, MDTopic: Long-term Toxicity Data of a Prospective Phase I/II Trial of Concurrent Paclitaxel and Radiation for High-risk or Post-operative Prostate Cancer.Results: Presented at American Society of Therapeutic Radiology and Oncology, Boston,

MA, 2008.

2007-2009 Ali Mirmiran, MDTopic: Long-Term Results of a Prospective, Phase II Study of Long-term Androgen Ablation, Pelvic Radiotherapy, Brachytherapy Boost and Adjuvant Docetaxel in Patients with High-Risk Prostate CancerResults: Manuscript accepted to International Journal of Radiation Oncology Biology Physics,

2010.

2007-2010 Ashish Patel, MDTopic: University of Maryland Experience of Gliasite Brachytherapy in Recurrents High-grade Gliomas.Results: Presented at the Radiologic Society of North America, Chicago, Il, 2008.

2008-2010 Matthew Koshy, MDTopic: Utilization and Impact of Radiation Therapy in Stage I and II Hodgkin’s DiseaseResults: Presented at the American Radium Society, Cancun, Mexico, May 2010 Young Investigator Award Will be presented at the American Society of Therapeutic Radiology and Oncology,

San Diego, CA, October 2010 Manuscript accepted to International Journal of Radiation Oncology Biology Physics,

2010.

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2009-2010 Grace Kim, MDTopic: Outcomes of AVM patients treated with Gamma Knife.

2011-present Elizabeth Nichols, MDTopic: Brain Metastasis—Perez Book Chapter update

2013-present Michael Rutenberg, M.D., Ph.D.Topic: Salvage external beam radiation in prostate brachytherapy failuresResults: Submitted abstract for American Society for Radiation Oncology, 2014 annual

meeting

2013-present Alexander Engelman, M.D.Topic: HIV and Prostate Cancer; Long Term Update of GCC 0166—High Risk Prostate

CancerResults: Submitted abstracts for American Society for Radiation Oncology, 2014 annual

meeting

2013-present James Snider, M.D.Topic: Long Term Update of GCC 0166—High Risk Prostate CancerResults: Submitted abstract for American Society for Radiation Oncology, 2014 annual

meeting

Clerkship Director, Children’s National Medical Center (Washington, DC) Pediatric Oncology Fellows (40 hours/week)May 10-14, 2010 Fellow: Yaser Diab, M.D.June 28-July 2, 2010 Fellow: Andrzek Rochowski, M.D.June 28-July 2, 2010 Fellow: Helkha Peredo-Pinto, M.D.July 26-30, 2010 Fellow: Burak Gumuscu, M.DMarch 11-18, 2011 Fellow: Leslie Doros, M.D.March 11-18, 2011 Fellow: Theresa Watson, M.D.June 27-July 1, 2011 Fellow: Karim Sadak, M.D.August 15-19, 2011 Fellow: Caitlin Neri, M.D.July 23-27, 2012 Fellow: Surbhi Saini, M.D.July 23-27, 2012 Fellow: Megha Kaushal, M.D.July 31-Aug 3, 2012 Fellow: Violet Fernandes, M.D.July 31-Aug 3, 2012 Fellow: Payal Khincha, M.D.July 29-Aug 2, 2013 Fellow: Nicole Drezner, M.D.July 29-Aug 2, 2013 Fellow: Bahey Salem, M.D.August 19-23, 2013 Fellow: Ekta KapadiaAugust 19-23, 2013 Fellow: Sucharita Bhaumik

Grant SupportJune 2006 – June 2011 PI (5 %)

Phase II Study Evaluating Bone Marrow-Sparing, Image-Guided Pelvic Intensity-Modulated Radiotherapy (IMRT) with Cesium-131

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Brachytherapy Boost, Adjuvant Chemotherapy, and Long-Term Hormonal Ablation in Patients with High Risk, Non-Metastatic Prostate Cancer.

Industry Grant: Isoray Corp., Richland, WATotal Direct and Indirect Costs: $200,000

Aug 2008 – Aug 2010 PI (0 %)A Phase I Study Evaluating Escalating Doses of Docetaxel Concurrently with Bone Marrow-Sparing, Image-Guided Pelvic Intensity-Modulated Radiotherapy (IMRT) and Long-Term Androgen Ablation in Patients with High-Risk, Non-Metastatic Prostate Cancer.Seed Grant: Cancer and Leukemia Group B (CALGB)Total Direct and Indirect Costs: $88,000

Sept 2010 – Sept 2011 Co-PI (0 %; PI – Rao Gullapalli, PhD)GCC 1008: Neuroimaging Correlates in Evaluating Cognitive Function

Following Radiation Therapy.U of MD Dept of Radiation Oncology Pilot Project Project AwardTotal Direct and Indirect Costs: $50,000 (no salary, imaging only)Pending CRC/IRB approvalsRole: Assisted in the design of the study. Will enroll patients. Will

assist in analyzing and publishing results.

Sept 2010 – Sept 2011 Co-PI (0 %; PI – France Carrier, PhD)Radiosensitizing Effect of Histone Deacetylase Inhibitors for the

Treatment of Glioblastoma Multiforme with Low-Dose Fractionated Radiation Therapy (LDFRT) in Combination with Radiation Therapy

U of MD Dept of Radiation Oncology Pilot Project AwardTotal Direct and Indirect Costs: $50,000 (post-doc support)Role: Assisted in designing the basic science research. Based on these

results, phase I/II trial was designed—currently enrolling.

PublicationsPeer-Reviewed Journal Articles1. Kwok Y , DiBiase S, Amin P, Naslund M, Jacobs S. Risk group stratification in patients undergoing

permanent I-125 prostate brachytherapy as monotherapy. International Journal of Radiation Oncology Biology Physics 2002, 53(3), 588-594.

2. Flannery T, Suntharalingam M, Kwok Y, Koffman B, Amin P, Chin L, Nicol B, Fowler B, Young AB, Regine W. Gamma Knife stereotactic radiosurgery for synchronous versus metachronous solitary brain metastases from non-small cell lung cancer. Lung Cancer 2003, 42, 327-333.

3. Thomas L, Kwok Y, Edelman M. Management of paraneoplastic syndromes in lung cancer. Current Treatment Options in Oncology 2004, 5(1), 51-62.

4. Herman JM, Petit JH, Amin P, Kwok Y, Dutta P, Chin LS. Repeat gamma knife radiosurgery for refractory or recurrent trigeminal neuralgia: Treatment outcomes and quality of life assessment. International Journal of Radiation Oncology Biology Physics 2004, 59(1), 126-133.

5. Garofalo M, Kwok Y, Regine WF. The Evolving Role of Adjuvant Postoperative Radiation Therapy. Surgical Oncology Clinics of North America 2004 Oct;13(4):589-604, viii.

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6. Patel AB, Edelman MJ, Kwok Y, Krasna M, Suntharalingam M. Predictors of acute esophagitis in patients with non-small cell lung carcinoma treated with concurrent chemotherapy and hyperfractionated radiation therapy followed by surgery. International Journal of Radiation Oncology Biology Physics 2004 Nov;60(4),1106-12.

7. DiBiase S, Kwok Y, Yovino S, Arena C, Temple R, Regine W, Amin P, Chin L. Factors predicting local tumor control after gamma knife stereotactic radiosurgery for benign intracranial meningiomas. International Journal of Radiation Oncology Biology Physics 2004 Nov 15;60(4):1106-12.

8. Kwok Y , Regine WF, Patchell RA. Radiation therapy alone for spinal cord compression: time to improve upon a relatively ineffective status quo. Journal of Clinical Oncology 2005 May 20;23(15):3308-10. Epub 2005 Feb 28.]

9. Yovino S, Kwok Y, Krasna M, Bangalore M, Suntha M. An association between preoperative anemia and decreased survival in early-stage non-small cell lung cancer treated with surgery alone. International Journal of Radiation Oncology Biology Physics 2005 Aug 1;62(5):1438-4.

10. Ma L, Kwok Y, Chin LS, Simard JM, Regine WF. Concomitant GRID boost for Gamma Knife radiosurgery. Medical Physics 2005 Nov;32(11):3419-23.

11. Ma L, Kwok Y, Chin LS, Yu C, Regine WF. Comparative analyses of linac and Gamma Knife radiosurgery for trigeminal neuralgia treatments. Phys Med Biol 2005 Nov 21;50(22):5217-27. Epub 2005 Oct 24.

12. D’Souza W, Kwok Y, DeYoung C, Zacharapoulos N, Pepelea M, Klahr P, and Yu CX. Gated CT imaging using a free-breathing respiration signal from flow-volume spirometry. Medical Physics 2005 Dec;32(12):3641-49.

13. Kwok Y , DeYoung C, Garofalo M, Dhople A, and Regine W. Radiation Oncology Emergencies. Hematology/Oncology Clinics of North America April 2006;20(2):505-522.

14. Kwok Y , Tibbs PA, Patchell RA. Clinical approach to metastatic epidural spinal cord compression. Hematology/Oncology Clinics of North America Dec 2006;20(6):1297-1305.

15. D’Souza W, Nazareth D, Zhang B, Deyoung C, Suntharalingam M, Kwok Y, Yu CX, and Regine W. The use of gated and 4D CT imaging in planning for stereotactic body radiation therapy. Medical Dosimetry 2007 Summer;32(2):92-101.

16. Dhople A, Kwok L, Chin L, Shepard D, Slawson R, Amin P, and Regine W. Efficacy and quality of life outcomes in patients with atypical trigeminal neuralgia treated with gamma-knife radiosurgery. Int J Radiat Oncol Biol Phys 2007;69(2):397-403. Epub 2007 Apr 30.

17. Flannery TW,Suntharalingam M, Regine WF, Chin LS, Krasna MJ, Shehata MK, Edelman MJ, Kremer M, Patchell RA, and Kwok Y. Long-term survival in patients with synchronous, solitary brain metastasis from non-small cell lung cancer treated with radiosurgery. Int J Radiat Oncol Biol Phys 2008 Sept 1;72(1):19-23. Epub 2008 Feb 13.

18. Dhople AA, Adams JR, Maggio WW, Naqvi SA, Regine WF, and Kwok Y. Long Term Outcomes of Gamma-Knife Radiosurgery for Classic Trigeminal Neuralgia: Implications of Treatment and Critical Review of the Literature. J Neurosurg 2009: 1-8. Epub 2009 March 27.

19. Settle K, Taylor R, Wolf J, Kwok Y, Cullen K, Carter K, Ord R, Zimrin A, Strome S, and Suntharalingam M. Race impacts outcome in stage III/IV squamous cell carcinomas of the head and neck after concurrent chemoradiation therapy. Cancer 2009; 115(8):1744-52.

20. Yovino S, Settle K, Taylor R, Wolf J, Kwok Y, Cullen K, Ord R, Zimrin A, Strome S,and Suntharalingam M. Patterns of failure among patients with squamous cell carcinoma of the head and neck who obtain a complete response to chemoradiotherapy. Head Neck 2010;32(1):46-52. Epub 2009 May 29.

21. Kwok Y , Yovino S. Radiation-based therapies for prostate cancer. Curr Opin Oncol 2010 May;22(3):257-62.

22. DiBiase SJ, Hussain A, Kataria R, Amin P, Bassi S, Dawson N, and Kwok Y. Long-term results of a prospective, phase II study of long-term androgen ablation, pelvic radiotherapy, brachytherapy boost and adjuvant docetaxel in patients with high-risk prostate cancer. International Journal of Radiation Oncology Biology Physics 2011;81(3):732-6. Epub 2010 Oct30.

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23. Hussain A, Wu Y, Mirmiran A, DiBiase S, Goloubeva O, Bridges, Mannuel H, Engstrom C, Dawson N, Amin P and Kwok Y. Long-term follow-up of a prospective trial of trimodality therapy of weekly paclitaxel, radiation and androgen deprivation in high risk prostate cancer with or without prior prostatectomy. International Journal of Radiation Oncology Biology Physics 2012;82(1):167-74. Epub 2010 Oct 30.

24. Szerlip N, Rutter C, Ram N, Yovino S, Kwok Y, Maggio W, Regine W. Factors impacting volumetric white matter changes following whole-brain radiation therapy. Journal of Neuro-Oncology 2011;103(1):111-9. Epub 2010 Aug 20

25. Koshy M, Rich SE, Mahmood U, Feigenberg S, and Kwok Y. The Declining Utilization of Radiation Therapy in Stage I and II Hodgkin's Disease and its Impact on Survival and Secondary Malignancies. In Press. International Journal of Radiation Oncology Biology Physics 2011.

26. Suntharalingam M, Kwok Y, Goloubeva O, Parekh A, Taylor R, Wolf J, Zimrin A, Strome S, Ord R, and Cullen K. A Phase II Study Evaluating the Addition of Cetuximab to the Concurrent Delivery of Weekly Carboplatin, Paclitaxel and Daily Radiotherapy for Patients with Locally Advanced Squamous Cell Carcinomas of the Head and Neck. International Journal of Radiation Oncology Biology Physics 2011 May 19. [Epub ahead of print]

27. Koshy M, Rich S, Merchant E, Mahmood U, Regine W, and Kwok Y. Post-operative Radiation Improves Survival in Children Younger Than 3 Years with Intracranial Ependymoma. Journal of Neuro-oncology. 2011;105(3):583-90. Epub 2011 June 3.

28. Husain ZA, Regine WF, Kwok Y and Feigenberg SJ. Brain Metastases: Contemporary Management and Future Directions. The European Journal of Clinical & Medical Oncology. June 2011, 3(3). 38-45.

29. Koltz MT, Polifka AJ, Saltos A, Slawson RG, Kwok Y, Aldrich EF, and Simard JM. Long-Term Outcome of Gamma Knife Stereotactic Radiosurgery for Arteriovenous Malformations Graded by the Spetzler-Martin Classification. Journal of Neurosurgery 2012;Oct 19. [Epub ahead of print].

30. Diss E, Nalabothula N, Nguyen D, Chang E, Kwok Y, and Carrier F. Vorinostat SAHA Promotes Hyper-Radiosensitivity in Wild Type p53 Human Glioblastoma Cells. JSM Clin Oncol Res 2014; 2(1): 1004.

31. Tye K, Engelhard HH, Slavin KV, Nicholas MK, Chmura SJ, Kwok Y, Ho DS, Weichselbaum RR, Koshy M. An analysis of radiation necrosis of the central nervous system treated with bevacizumab. J Neurooncol 2014; Feb 7. [Epub ahead of print].

Non-refereed:1. Kwok Y , Patchell RA. Commentary on: “The role of radiation in the management of brain

metastases from renal cell carcinoma.” Doh, Amato, Paulino et al. Oncology May 2006;20(6):619-625.

Book Chapters:1. Kwok Y , Garofalo M, Regine WF. Postoperative Adjuvant Therapy for Pancreatic Cancer. In:

Pancreatic Cancer. Von Hoff DD, Evans DB, and Hruban RH (ch.27, p395-404). Sudbury, MA: Jones and Barlett, 2005.

2. Kwok Y , Patchell RA, Regine WF. Palliation of Brain and Spinal Cord Metastases. In: Principles and Practice of Radiation Oncology (ch.91, p1974-1985). Lippincott Williams & Wilkins; 5th edition. 2007.

3. Miker-Zabel S, Kwok Y, Debus J. Skull Base Tumors. In: Principles and Practice of Stereotactic Radiosurgery (ch.37, p383-392). Springer; 1st edition. 2008

4. Chin LS, Patel S, Mattingly T, Kwok Y. Trigeminal Neuralgia. In: Principles and Practice of Stereotactic Radiosurgery (ch.52, p519-526). Springer; 1st edition. 2008

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5. Kwok Y , Patchell RA, Regine WF. Management of Overt CNS Metastases: Brain and Spinal Cord. Lung Cancer: Principles and Practice. Lippincott Williams & Wilkins; 4th edition. April 2010.

6. Yovino S, Kwok Y, Regine WF. Brain and Cranial Nerves. In: ALERT: Adverse Late Effects of Cancer Treatment, Volume 2: Specific Normal Tissue Sites. Rubin P, Constine L, Marks L, Williams J, Hansen J. New York, NY: Springer-Verlag, 2012.

7. Nichols E, Patchell RA, Regine WF, Kwok Y. Palliation of Brain and Spinal Cord Metastases. In: Principles and Practice of Radiation Oncology. Lippincott Williams & Wilkins; 6th edition. 2013

Other Brief Communications:1. Kwok Y , Regine W, Dibiase SJ. In reply to Dr. Rogers et al. International Journal of Radiation

Oncology Biology Physics 2005 Jun 1;62(2):618-9.2. Kwok Y , Patchell RA, Regine W. In reply to Dr. Macbeth et al and Dr. Maranzano et al. Journal of

Clinical Oncology 2005;23(32):8272-8275.3. Mahmood U, Kwok Y, Regine WF, and Patchell RA. Whole brain irradiation for patients with

brain metastasis: still the standard of care. Lancet Oncol 2010;11(3):221-2.

Abstracts/Presentations (Selected):1. Kwok Y , Lanzkowsky P, Karayalcin G. Childhood neutropenias: A fifteen year experience. Poster

Presentation at American Society of Hematology, Miami, Fl, December 1998.2. Kennedy A, Murthy R, Kwok Y, Kanani S, Tucker G, Desai K, van Echo D. Preliminary results of

outpatient hepatic artery brachytherapy for colorectal hepatic metastases. Oral Presentation at European Cancer Conference, Lisbon, Portugal, October 2001.

3. Kwok Y , DiBiase S, Amin P, Naslund M, Jacobs S. Risk group stratification in patients undergoing permanent I-125 prostate brachytherapy as monotherapy. Oral Presentation at Radiological Society of North America, Chicago, Il, October 2001.

4. Kennedy A, Murthy R, Kwok Y, Tucker G, Kanani S, Desai K, van Echo D. Hepatic artery brachytherapy for unresectable hepatocellular carcinoma: an outpatient treatment approach. Oral Presentation at Internation Congress on Anti-Cancer Treatment, Paris, France, February 2002.

5. Kwok Y , Suntharalingam M, Taylor R, Baig F, Yaes R, Mohiuddin M, Regine W. A definitive evaluation of the impact of treatment related factors on local control in patients with T1 glottic tumors utilizing Linear-Quadratic Plus Time model. Oral Presentation at Radiological Society of North America, Chicago, Il, November 2002.

6. Kennedy A, Yovino S, Kwok Y, Duckham E, van Echo D. Long-term follow-up of upper GI cancers after conformal radiotherapy combined with paclitaxel or capecitabine plus paclitaxel. Oral Presentation at Radiological Society of North America, Chicago, Il, November 2002.

7. Ronson S, DiBiase S, Kwok Y, Amin P, Naslund M, Jacobs S. Incidence and temporal pattern of hematuria and proteinuria in men treated with permanent interstitial prostate brachytherapy. Poster Presentation at American Radium Society, Houston, Tx, April 2003.

8. Kwok Y , DiBiase S, Yovino S, Arena C, Temple R, Regine W, Amin P, Chin L. Improved outcome with adequate dural tail coverage in patients with intracranial meningiomas treated with Gamma Knife stereotactic radiosurgery. Poster Discussion at American Society of Therapeutic Radiology and Oncology, Salt Lake City, Ut, October 2003

9. Kennedy A, Kwok Y, Batko-Yovino S, van Echo D. A phase I study of preoperative capecitabine, irinotecan concurrent with radiation therapy for resectable rectal cancer. Poster Presentation. American Society of Clinical Oncology GI Symposium, San Francisco, Ca, January 2003.

10. Yovino S, BA, Kwok Y, Krasna M, Bangalore M, Suntha M. Preoperative Anemia Decreases Survival in Patients with Stage I and II Non-Small-Cell Lung Cancer Treated with Surgery. Poster Presentation at American Society of Therapeutic Radiology and Oncology, Atlanta, Ga, October 2004.

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11. Kwok Y , Murali N, Chin L, Bangalore M, Amin P, and Regine W. Long-term Results of Gamma Knife Stereotactic Radiosurgery for Non-functioning Pituitary Adenomas. Poster Presentation at American Society of Therapeutic Radiology and Oncology, Atlanta, Ga, October 2004.

12. Dutta, P.R., Kwok Y, Chin, L.S., Herman, J.M., Colliver, C., St. Clair, W., Petit, J., Young, B., and Regine, W.F. Comparison of Repeat GK-SRS for Refractory or Recurrent Trigeminal Neuralgia: Does Dose Matter? Poster Presentation at American Society of Therapeutic Radiology and Oncology, Atlanta, Ga, October 2004.

13. Sullivan P, Ord R, Gray W, Wolf J, Taylor R, VanEcho D, Kwok Y, Suntharalingam M. Long-term survival and functional quality of life assessments in patients with locally advanced unresectable squamous cell carcinomas of the head and neck treated with concurrent chemoradiation. Poster Presentation at American Society of Therapeutic Radiology and Oncology, Atlanta, Ga, October 2004.

14. Patel S, Kwok Y, Shepard D, Chin L, Slawson R, Amin P, and Regine W. Evaluating the influence of dose-rate on outcome with gamma-knife stereotactic radiosurgery in the treatment of trigeminal neuralgia. Poster Presentation at American Society of Therapeutic Radiology and Oncology, Denver, Co, October 2005.

15. SJ DiBiase, N Dawson, Y Kwok, R Kataria, A Hussain, S Nagda, M Bangalore, P Amin. Phase II Trial of External Radiotherapy, Brachytherapy, Androgen Deprivation, and Docetaxel Chemotherapy for High-Risk, Localized Prostate Cancer. Poster Presentation at American Society of Therapeutic Radiology and Oncology, Denver, Co, October 2005.

16. Dhople A, Kwok Y, Jaboin J, Chin L, Slawson R, Amin P and Regine W. Evaluation of Efficacy and Quality of Life in Patients with Atypical Facial Pain Treated with Gamma-Knife Stereotactic Radiosurgery. Oral Presentation at American Society of Therapeutic Radiology and Oncology, Denver, Co, October 2005.

17. Flannery T, Kwok Y, Naslund M, and Amin P. Long-term Results of Intermediate and High-Risk Prostate Cancer Patients Treated with Prostate Brachytherapy. Poster Presentation (Resident Travel Grant for Todd Flannery, M.D.) at American Brachytherapy Society, Philadelphia, PA, May 2006.

18. Flannery T, Kwok Y, Krasna L, Chin L, Shehata M, Kremer M, Jaboin J, Suntha M, Regine W. The Impact of Definitive Thoracic Management on Long-Term Survival in Patients with Synchronous, Solitary Brain Metastases from Non-Small Cell Lung Cancer Treated with Stereotactic Radiosurgery. Oral Presentation at American Society of Therapeutic Radiology and Oncology, Philadelphia, Pa, November 2006.

19. Thomas O, Kwok Y, Dhople A, Chin L, Slawson, Regine W, Long-term outcome of patients treated with Gamma Knife stereotactic radiosurgery for brain metastases secondary to malignant melanoma or renal cell carcinoma. Poster Presentation at Radiological Society of North America, Chicago, Il, November 2006

20. Settle K, Taylor R, Wolf J, Kwok Y, Cullen K, Carter K, Ord R, Zimrin A, Strome S and Suntharalingam M. Race Impacts Outcome in Stage III/IV Squamous Cell Carcinomas of the Head and Neck Following Concurrent Chemoradiation Therapy. Poster Discussion at American Society of Therapeutic Radiology and Oncology, Los Angeles, November 2007.

21. Kwok Y , Won M, Regine WF, Mehta M, Schmitt F, Patchell RA, and Watkins-Bruner D. Neurocognitive Impact of Whole Brain Radiation on Patients With Brain Metastases: Secondary Analysis of RTOG BR-0018. Oral Presentation at American Society of Therapeutic Radiology and Oncology, Los Angeles, November 2007.

22. Adams JR, Dhople AA, Kwok Y , Yu XU, Simard JM, Maggio W and Regine. Long Term Follow-up of Gamma Knife Stereotactic Radiosurgery for Trigeminal Neuralgia. Oral Presentation at American Society of Therapeutic Radiology and Oncology, Los Angeles, November 2007.

23. Dhople AA, Adams JR, Kwok Y, Yu XU, Simard JM, Maggio W and Regine WF. Long Term Follow-up of Repeat Gamma Knife Stereotactic Radiosurgery for Refractory or Recurrent Trigeminal Neuralgia. Oral Presentation at American Society of Therapeutic Radiology and Oncology, Los Angeles, November 2007.

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24. Carter K, Settle K, Taylor R, Wolf J, Kwok Y, Cullen K, Ord R, Zimrin A, Strome S and Suntharalingam. Site as a Prognostic Factor in Patients with Stage III/IV Squamous Cell Carcinoma of the Head and Neck Following Definitive Chemoradiation. Poster Presentation at American Society of Therapeutic Radiology and Oncology, Los Angeles, November 2007.

25. Yovino S, Settle K, Taylor R, Wolf J, Kwok Y, Cullen K, Ord R, Zimrin A, Strome s and Suntharalingam M. Can Adjuvant Neck Dissection be Deferred in Locally Advanced Head and Neck Cancer Patients With Complete Response to Definitive Chemoradiotherapy? Oral Presentation at American Society of Therapeutic Radiology and Oncology, Los Angeles, November 2007.

26. Patel AB, Edelman M, Burrows W, Hausner P, Kwok Y, Krasna M and Suntharalingam M. The Impact of Prophylactic Cranial Irradiation in Patients with Locally Advanced Non-Small Cell Lung Cancer Treated With Trimodality Therapy. Poster Discussion at American Society of Therapeutic Radiology and Oncology, Los Angeles, November 2007.

27. Kwok Y , Kataria R, Amin P, Naslund M, Hussain A, Dawson N, and Dibiase S. Long-term Results of a Prospective Phase II Trial of Androgen Ablation, Pelvic External Beam Radiation Therapy, Brachytherapy Boost, and Adjuvant Docetaxel in High-risk Prostate Cancer. Oral Presentation at American Society of Therapeutic Radiology and Oncology, Boston, Ma, September 2008.

28. Mahmood U, Richards L, D'Souza W, Naslund M, Amin P and Kwok Y. Dosimetric Analysis of the Effect of Prostate Edema on Cs-131 Brachytherapy. Poster Presentation at American Society of Therapeutic Radiology and Oncology, Boston, Ma, September 2008.

29. Yovino SB, Rutter C, Szerlip N, Kwok Y, Maggio W and Regine WF. Long-term Survivors of Brain Metastases (BM) Have Optimal Brain Tumor Control with Combined Whole Brain Radiation (WBRT) and Stereotactic Radiosurgery (SRS). Poster Presentation at American Society of Therapeutic Radiology and Oncology, Chicago, Il, Noveber 2009.

30. Koshy M, Rich S, Merchant T, Regine W and Kwok Y. Postoperative Radiation Improves Overall Survival in Children Age <3 Years with Intracranial Ependymoma. Poster Presentation at American Society of Therapeutic Radiology and Oncology, Chicago, Il, November 2009.

31. Diwanji T, Dhople A, Chin L, Maggio W, Adams J, Regine W and Kwok Y. Long-term Outcome of Gamma Knife Stereotactic Radiosurgery for Multiple Sclerosis Associated Trigeminal Neuralgia. Poster Presentation at American Society of Therapeutic Radiology and Oncology, San Diego, Ca, November 2010.

32. Kwok Y , Wu Y, Mirmiran A, DiBiase S, Goloubeva O, Bridges B, Mannuel H, Dawson N, Amin P

and Hussain A. Prospective Trial of Escalating Doses of Paclitaxel, Concurrent Radiation and Androgen Deprivation in High Risk Prostate Cancer With or Without Prior Prostatectomy. Long-term Outcome of Gamma Knife Stereotactic Radiosurgery for Multiple Sclerosis Associated Trigeminal Neuralgia. Poster Presentation at American Society of Therapeutic Radiology and Oncology, San Diego, Ca, November 2010.

33. Regine W, Szerlip N, Rutter C, Ram N, Yovino S, Maggio W and Kwok Y. Factors Impacting White Matter Changes Following Whole Brain Radiation Therapy. Poster Presentation at American Society of Therapeutic Radiology and Oncology, San Diego, Ca, November 2010.

34. Saltos A, Koltz M, Aquino C, Obuchowski A, Kim G, Kwok Y, and Simard J. Staged-dose radiosurgical outcomes for symptomatic and asymptomatic intracranial arteriovenous malformations. Poster Presentation at American Society of Therapeutic Radiology and Oncology, Miami, Fla, October 2011.

35. Carrier F, Diss E, Nalabothula N, and Kwok Y. The histone deacetylase inhibitor vorinostat induces hyper-radiosensivity in P53 wild type glioblastoma cells. Poster Presentation at American Society of Therapeutic Radiology and Oncology, Miami, Fla, October 2011.

36. Kwok Y, Saltos A, Boggs D, Naslund M, Hussain A, and Amin P. Long-term follow-up of combined modality therapy with pelvic external radiation followed by Cs-131 brachytherapy boost in men with high-risk prostate cancer. Poster Presentation at American Society of Therapeutic Radiology and Oncology, Boston, Ma, October 2012.

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37. Kwok Y, Ferris M, Moshe M, Kataria R, Nickerson C. Interim Results of a Prospective Phase II Trial of Pelvic IMRT, Cesium-131 Brachytherapy Boost, Adjuvant Docetaxel Chemotherapy, and Long Term Androgen Ablation for Patients with High Risk Prostate Cancer. Oral Presentation at American Society for Radiation Oncology, Atlanta, Ga 2013.

Proffered Communications:1. Kwok Y , M Won, WF Regine, M Mehta, F Schmitt, RA Patchell, and D Watkins-Bruner.

Neurocognitive Impact of Whole Brain Radiation on Patients with Brain Metastases: Secondary Analysis of RTOG BR-0018. Oral Presentation at Radiation Therapy and Oncology Group, San Diego, Ca, January 19, 2008.

Invited Speeches1. February 12, 2002 Contemporary Management of Supratentorial High-Grade Gliomas.

Grand Rounds. Greenebaum Cancer Center, Univ of Maryland Medical Center, Baltimore, MD.

2. November 5, 2003 Introduction to Radiation Oncology. Greenebaum Cancer Center, Univ of Maryland Medical Center, Baltimore, MD.

3. December 10, 2003 Gamma Knife Stereotactic Radiosurgery for Trigeminal Neuralgia: University of Maryland Experience. Univ of Maryland Medical Center-CME Lecture. Baltimore, MD.

4. January 21, 2004 Gamma Knife Stereotactic Radiosurgery for Trigeminal Neuralgia: University of Maryland Experience. CME Lecture. Bethesda, MD.

5. March 9, 2004 Gamma Knife Stereotactic Radiosurgery for Trigeminal Neuralgia: University of Maryland Experience. CME Lecture. Annapolis, MD.

6. June 15, 2004 Contemporary Management of Central Nervous and Head and Neck Tumors. Greenebaum Cancer Center, Univ of Maryland Medical Center, Baltimore, MD.

7. June 19, 2004 Diagnosis and Treatment of Trigeminal Neuralgia. Greater Baltimore Medical Center, Baltimore, MD.

8. June 19, 2004 Gamma Knife Stereotactic Radiosurgery for Trigeminal Neuralgia: University of Maryland Experience. Greater Baltimore Medical Center, Baltimore, MD.

9. October 15, 2004 Diagnosis and Treatment of Trigeminal Neuralgia. Cambridge Dental Group, Cambridge, MD.

10. October 15, 2004 Gamma Knife Stereotactic Radiosurgery for Trigeminal Neuralgia: University of Maryland Experience. Cambridge Dental Group, Cambridge, MD.

11. November 15, 2004 Diagnosis and Treatment of Trigeminal Neuralgia. Holy Cross Hospital, Silver Spring, MD.

12. November 15, 2004 Gamma Knife Stereotactic Radiosurgery for Trigeminal Neuralgia: University of Maryland Experience. Holy Cross Hospital, Silver Spring, MD.

13. May 26, 2005 The Role of Radiotherapy in Genito-urinary Malignancies. Grand Rounds. Division of Urology, UMSOM, Baltimore, MD.

14. July 7, 2005 Introduction to Radiation Oncology. National Youth LeadershipForum. University of Maryland Medical Center, Baltimore, MD

15. November 12, 2005 Lymphoma Review. Annual Mid-Atlantic American Society of Therapeutic Radiology Oncology Review. UMSOM, Baltimore, MD

16. December 3, 2005 Management of Brain Metastasis from Lung Cancer. UMSOM Annual Thoracic Malignancy Update, Cambridge, MD

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17. October 12, 2006 Management of Spinal Cord Compression. European Society of Therapeutic Radiology and Oncology, Leipzig, Germany

18. December 7, 2006 CNS Review. Annual Mid-Atlantic American Society of TherapeuticRadiology Oncology Review. UMSOM, Baltimore, MD

19. December 15, 2006 Stage I and II Seminoma. Solid-Tumor Board. University of Maryland Medical Center, Baltimore, MD

20. March 23, 2007 Prostate Cancer: Treatment Overview. Solid-Tumor Board. University of Maryland Medical Center, Baltimore, MD

21. April 13, 2007 Prostate Cancer: Determinants of Outcome. Solid-Tumor Board. University of Maryland Medical Center, Baltimore, MD

22. June 2, 2007 Whole Brain Radiation Therapy in the Management of Brain Metastasis from Non-small Cell Lung Cancer. American Society of Clinical Oncology, Chicago, Il

23. October 25, 2007 CNS Malignancies. Greenebaum Cancer Center, Univ of Maryland Medical Center, Baltimore, MD.

24. December 13, 2007 Prostate Cancer: Treatment Overview. Greenebaum Cancer Center, Univ of Maryland Medical Center, Baltimore, MD

25. January 10, 2008 Genito-urinary Review. Annual Mid-Atlantic American Society of Therapeutic Radiology Oncology Review. UMSOM, Baltimore,

MD26. March 6, 2008 Chemoradiation in Locally-Advanced Cervical Cancer. Greenebaum

Cancer Center, Univ of Maryland Medical Center, Baltimore, MD27. March 26, 2008 Recent Technological Advances in Radiation Oncology. FDA: Center

for Devices and Radiological Health—The Federal Research Center @ White Oak, Silver Springs, MD

28. October 6, 2008 Contemporary Management of Non-metastatic Prostate Cancer. Grand Rounds. Greenebaum Cancer Center, Univ of Maryland Medical Center, Baltimore, MD

29. October 23, 2008 Contemporary Management of Non-metastatic Prostate Cancer. Grand Rounds. Division of Urology, UMSOM, Baltimore, MD

30. January 8, 2009 CNS Review. Annual Mid-Atlantic American Society of Therapeutic Radiology Oncology Review. UMSOM, Baltimore, MD

31. February 27, 2009 Introduction to Radiation Oncology. University of Maryland Radiation Oncology Interest Group. Univ of Maryland School of Medicine, Baltimore, MD

32. October 8, 2009 High-Risk Prostate Cancer: Are We There Yet? Grand Rounds. Laurel Regional Hospital, Laurel, MD.

33. November 11, 2009 Prostate: Technological Advances. UMMC Consumer Seminar SeriesPikesville Hilton, Pikesville, MD.

34. December 2, 2009 Introduction to Radiation Oncology. University of Maryland Radiation Oncology Interest Group. Univ of Maryland School of Medicine, Baltimore, MD

35. February 18, 2010 Recent Technological Advances in Radiation Oncology. Grand Rounds. Children’s National Medical Center. Washington, DC.

36. April 22, 2010 Recent Advances in Radiation Oncology for GU Cancers. Grand Rounds. Upper Chesapeake Medical Center, Bel Air, MD.

37. October 18, 2010 Contemporary Management of Muscle-Invasive Bladder Cancer. Grand Rounds. Greenebaum Cancer Center, Univ of Maryland Medical Center, Baltimore, MD

38. January 6, 2011 GU Review. Annual Mid-Atlantic American Society of Therapeutic Radiology Oncology Review. UMSOM, Baltimore, MD

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39. March 3, 2011 Role of Radiation Therapy in Pituitary Adenomas. Endocrinology Fellows Lecture. Division of Endocrinology, Univ of Maryland Medical Center, Baltimore, MD

40. October 13, 2011 Trigeminal Neuralgia. Grand Rounds. Dept of Neurosurgery, Univ of Maryland Medical Center, Baltimore, MD

41. March 8, 2012 Post-Prostatectomy Radiation. Grand Rounds. Division of Urology,Univ of Maryland Medical Center, Baltimore, MD

41. May 30, 2012 PSA Screening Controversy. Grand Rounds. Internal Medicine. HarborHospital, Baltimore, MD

42. September 13, 2012 Role of Brachytherapy in High-Risk Prostate Cancer. Visiting Professor.Grand Rounds. Georgetown University. Washington, DC.

43. January 24, 2013 Extent of Resection in Brain Tumors. Grand Rounds. Dept of Neurosurgery, Univ of Maryland Medical Center, Baltimore, MD

44. October 24, 2013 PSA Screening Controversy. Grand Rounds. Internal Medicine. LaurelRegional Hospital, Baltimore, MD

45. January 9, 2014 GU Review. Annual Mid-Atlantic American Society of Therapeutic Radiology Oncology Review. UMSOM, Baltimore, MD

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