33f skin patches 3. 2 1 mccune albright 13m bone age - esrd 2
TRANSCRIPT
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33FSkin patches
3
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33FSkin patches
2
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33FSkin patches
1
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33FSkin patches
• McCune Albright
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13MBone Age - ESRD
2
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13MBone Age - ESRD
1 year later
1
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• Healing rickets distal ulna
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25M
1
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25M
• Osteopoikilosis • Benign sclerosing bone dysplasia• Melorrheostosis• Osteopathiastriata
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35MChronic illness
6
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35MChronic illness
5
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35MChronic illness
4
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35MChronic illness
3
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35MChronic illness
2
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35MChronic illness
1
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35MChronic illness
• ROD
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66F
3
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66F
2
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66F
1
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66F
• Fibrous Dysplasia
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43F
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43F
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RTA-ROD
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29M
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29M
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29M
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POFD
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53M
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53M
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53M
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53M
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Renal Tx – ROD - AVN
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57FBone pain
8
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57FBone pain
7
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57FBone pain
6
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57FBone pain
5
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57FBone pain
4
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57FBone pain
3
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57FBone pain
2
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57FBone pain
1
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Gauchers
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49MBone pain
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49MBone pain
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Poly osstotic fibrous dysplasia
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25F
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25F
25F
4
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25F
25F
3
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25F
25F
2
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25F
25F
1
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Primary oxalosissecondary hyperparathyroidism
• Primary• Hereditary hyperoxaluria• AR, enzyme deficiency - carboligase• Diffuse calcium oxalate deposits
• Secondary• Disturbance of bile acid metabolism• Usually diseases of terminal ileum
25F
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Acroosteolysis
• Tuft• CVD, Psoriatic, Neuropathic, Thermal, Trauma, HPT,
Porphyria, Epidermolysis bullosa, Phenytoin toxicity, Subungal exostosis, Snake venom
• Middle• HPT, Hajdu Cheney, PVC
• Periarticular• Psoriatic, Erosive OA, HPT, Thermal injury, Scleroderma,
Multicetric reticulohistiocytosis
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20F
1
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Familial osteolysis
20F
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7MKyphosis
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Mucolipidosis 3 - PseudoHurlers
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Newborn
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Newborn
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Newborn
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3mMShort
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3mMShort
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32MStiffness and decreased ROM since child
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32MStiffness and decreased ROM since child
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Trevors disease
• Dysplasia epiphysialis hemimelica
32M Stiffness and decreased ROM since child
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29FShort stature
8
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29FShort stature
7
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29FShort stature
6
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29FShort stature
5
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29FShort stature
4
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29FShort stature
3
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29FShort stature
2
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29FShort stature
1
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Diastrophic dwarf
29F Short stature
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57ML hip pain
2
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Sandwich vertebrae - Osteopetrosis
57ML hip pain
1
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Osteopetrosis
• Marble bone, Defective osteoclasts
• AR, Infantile, Systemic, Leukaemia
• AD, Adult, Fxs, anaemia, CN palsy
• Sclerotic, peri and endosteal
• Erlenmyer flask
• Bone in bone, sandwich vertebrae
• Calvaria and mandible spared
57M L hip pain
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67FLump
2
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67FLump
1
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Fibrous Dysplasia
• Common
• Hamartomatous fibro-osseous metaplasia
• 70% monoostotic
• Polyostotic tends to be unilateral
• Usually expansile
• Shepherds crook, ground glass
• Any bone, but spine unusual
67F Lump
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Variable patients Same condition
6
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Variable patients Same condition
5
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Variable patients Same condition
4
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Variable patients Same condition
3
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Variable patients Same condition
2
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Variable patients Same condition
1
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Pseudohypoparathyroidism
• X-linked, renal and skeletal resistance to PTH
• Short, retarded,
• Decreased Ca, normal/increased PTH
• Brachydactyly 1,4,5 MC
• Ca basal ganglia, skin, SubQ
Variable patients Same condition
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Same condition Various patients
8
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Same condition Various patients
7
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Same condition Various patients
6
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Same condition Various patients
5
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Same condition Various patients
4
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Same condition Various patients
3
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Same condition Various patients
2
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Same condition Various patients
1
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Dermatomyositis
• Damaged chondroitin sulfate
• Atrophy, oedema, necrosis of muscle
• 30-60, F>M
• Calcification extremities and girdles
• Pointing of tufts
• Ass. Malignancy, lung, kidney, ovary, breast
Same condition Various patients
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37F acute torticollis, stiffness and shortness of breath
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Fibrodysplasia ossificans progressiva
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• MOP / Stone man
• Rare, AD, sporadic
• Presents in childhood
• Stiffness, Heterotopic ossification
• Malformed fingers and toes
• Bone morphogenic protein (BMP) signaling pathway problem
Fibrodysplasia ossificans progressiva
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Variable agesincreasing stiffness
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Fibrodysplasia ossificans progressiva
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• MOP / Stone man
• Rare, AD, sporadic
• Presents in childhood
• Stiffness, Heterotopic ossification
• Malformed fingers and toes
• Bone morphogenic protein (BMP) signaling pathway problem
Fibrodysplasia ossificans progressiva
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48M joint pains and dark pigmentation on ears
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Alkaptonuria
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Alkaptonuria / Ochronosis
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Alkaptonuria / Ochronosis
• Absence of homogentisic acid oxidase
• Pigmentation
• Arthropathy
• Osteoporotic with dense disc calcification
• Larger joints show DJD
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6mMCalcareous nodules
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Idiopathic calcinosisuniversalis
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Idiopathic calcinosisuniversalis
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50FLife long problems
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OGI
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OGI
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45MITC
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ITC
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ITC
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23M
Hemophilia
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Hemophilia
23M
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Mastocytosis
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65
Mastocytosis
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65
Mastocytosis
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65
Mastocytosis
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65
Mastocytosis
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65
Mastocytosis
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65 MastocytosisHistamine release causes lucency, bodies reaction causes sclerosis.
Mastocytosis
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Cherub - Fibrous Dysplasia
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16mF
Dysostosis multiplex
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4M
Morquio’s
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24F
NF1
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22F
Calcinosis Interstitialis UniversalisDermatomyositis
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McCune Albright
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9F
McCune Albright
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Polyostotic fibrous dysplasia
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24M
Polyostotic fibrous dysplasia
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Polyostotic fibrous dysplasia
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28BF mass in shoulder
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Idiopathic Tumoral Calcinosis
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63F
ITC
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ITC
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Rib osteochondroma
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Rib osteochondroma
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Rib osteochondroma
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Massive osteolysis
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Massive osteolysis
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Massive osteolysis
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Multiple hereditary exostoses
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Multiple hereditary exostoses
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Multiple hereditary exostosis
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Multiple hereditary exostoses
21mF
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Multiple hereditary exostoses
21mF
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Multiple hereditary exostoses
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NewbornFLK
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OGI
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Camurati Engelman
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Camurati Engelman
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Camurati Engelman
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Metaphyseal dysplasia
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Metaphyseal dysplasia
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Metaphyseal dysplasia