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    er ca on ev ew ourse

    S. Renee Hill, RN BSN CNNIn-Service Education Coordinator

    Central Florida Kidney Center

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    Physiology

    Failure ev ew o rea men o a es

    Vascular Access

    Renal Diet & Fluid Restrictions

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    -

    170 grams (size of afist

    20% of Cardiac

    Out ut 1 L/min of blood

    120 ml/min of plasma

    is filtered

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    Work 24 hours 7 daysa week

    Maintain a constant

    balance of chemicals

    Most people have 2kidne s

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    Renal Anatom & Ph sioloHow Healthy Kidneys Work

    Blood with waste enters theRenal Artery

    Each kidney has over a millionnephrons

    Filtration occurs in theGlomerulus

    Urine goes to Collecting duct to

    Filtered blood flows through theRenal Vein & back to the body

    connecting the kidney to thebladder. Waste products leavethe kidneys via the bladder. Thewaste s ca e ur ne.

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    The Ne hron The workin unit of the kidne

    Filters and cleans the blood, discards

    Keeps the body in balance (Homeostasis)

    m on o em per ney

    Made up of a Glomerulus and a tubule

    Nephrons empty into collecting ducts

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    capillaries heldtogether by amembrane called the

    Bowmans capsule. The capillary walls

    are semipermeable

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    Blood enters each glomerulus from an afferent

    (toward the organ) arteriole (small artery) Blood pressure forces water to filter out the

    blood-through tiny slits-into the urinary space of

    a glomerulus ma was es pass roug pores a ong w e

    water to form a liquid called Glomerular filtrate.

    u -180 liters/day.

    ,

    substances, like protein, pass through)

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    -

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    Glomerulus sends filtrate into a tubule

    Tubule has 4 parts: Proximal Convoluted Tubule

    Loop of Henle

    Distal Convoluted Tubule

    Chemicals and water the body needs arereabsorbed into the blood throu h thetubules, the rest gets emptied and then flowsinto the ureters to be excreted as urine.

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    a. Medulla

    .

    c. Calyx

    .

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    a. A glomerulus and a tubule

    . nep ron an a capsu e

    c. The Loop of Henle and a capillary bedd. The Bladder and the ureter

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    -

    W Water Removal

    ectro yte a ance

    T Toxin Removal B Blood Pressure Control

    D Vitamin D Metabolism

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    -

    The kidneys maintain acid-base balance

    blood plasma. a ys s e ps o res ore ac ase a ance

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    Intracellular: first space. Located within tissue and muscle

    ce s ns e e ce s . a es up o o a o y wa er.

    Intravascular: blood inside the blood vessels. Extracellular or Interstitial: second space. Is composed of

    . Whole blood is in both the intracellular and extracellular

    compartment Transcellular: third s ace. Makes u a rox 1-3% of bod

    water. It exists in various compartments: Cerebrospinal Pleural

    Peritoneal Gastrointestinal

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    intravascular fluid compartment?.

    b. Blood inside the blood vesselsc. Fluid between cells

    d. Fluids inside and between cells

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    , ,

    pass through the kidneys go back into.

    Sodium, Potassium, Chloride, Calcium,.

    Dialysis helps to restore electrolyte

    a ance.

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    -Rid the body of waste and excess fluid

    astes comes rom oo s t at are

    digested Wastes come from the breakdown of

    tissue due to normal muscle use

    Dialysis removes some waste ontreatment da s

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    pressure control,

    with sodium

    a ys s e ps o con ro oo pressure yremoving fluid and balancing sodium on

    rea men ays

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    make red blood cells by producing

    Antidiuretic Hormone- released by the

    pressure

    a ys s can ma e ery ropo e n, uerythropoietin can be given.

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    -

    Calcium and Phosphorus balance thathel s with bone metabolism

    Dialysis cannot activate Vitamin D, but

    Vitamin D sterols can be iven. Dialysis can change Ca levels by adjusting

    Ca in dialysate and some Phosphorus can

    be removed, but not as well as healthykidneys

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    ron c ney sease

    End Stage Renal Disease

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    Sudden loss of kidne function

    Causes: -

    Severe Dehydration Heart Disease

    - Trauma Nephrotoxic Drugs

    Postrenal-blocka e causin urine back-u

    Kidney Stones Kinked ureter Tumors

    Lasts days, weeks, months

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    ,

    functions over a period of months or years

    glomerular filtration rate.

    in blood serum.

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    CKD that leads to severe illness and.

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    How to Slow Kidney Disease

    Progression

    Blood Pressure Control

    et

    Blood sugar control in Diabetics Stop smoking

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    Stages of Chronic Kidney Disease

    Stage GFR Description

    no symptoms

    - ney amage w t ecreaseGFR; Anemia

    3 30-59 Moderate decrease in GFR;Fatigue, Anemia, Edema

    4 15-29 Severe decrease in GFR; preparept for dialysis or transplant

    5

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    Diabetic Nephropathy (Diabetic Kidney

    1-2 main types of Diabetes cause most kidney

    Type I Pancreas cant make Insulin

    Type II-The body cant make enough insulin or

    cant use what it makes (90% of pts)

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    2nd most common cause of CKD Cause usuall unknown

    Stress being overweight smoking

    High salt diet heavy use of alcohol

    Glomerular Disease

    -

    Glomerulosclerosis (narrow)-narrowing of glomeruli

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    disease for adults in the US?.

    b. Glomerulonephritis

    .

    d. Urinary Obstruction

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    Genetic cysts (fluid filled)

    Other Causes

    Birth defects, AIDS, Sickle Cell Disease, Useof street drugs, Cancer, Large Kidney Stones

    upus mmune sys em sease , rauma

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    Di h Tr m n

    Options for Kidney Failure

    Peritoneal Dialysis

    None

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    e process o c ean ng e oo y

    removing waste and fluid build-up whene neys a roug a sem -permea e

    membrane.

    Both blood and dialysate are pumpedthrough the dialyzer at the same time.

    Dialysis only replace 15% of kidneyfunction.

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    -

    Good fluid balance

    Anemia controlled

    w

    Blood tests in target range

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    -

    More energy

    Has a good appetite

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    membrane as the filter Membrane is inside the abdomen

    (Peritoneum)

    A plastic catheter is placed in theabdomen

    Minor surgery

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    -

    Can be done alone or with a partner

    -

    Fits into the patients lifestyle Allows working patients to keep their jobs

    Fewer Diet and fluid limits

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    Inflammation of the Peritoneum

    How to prevent Peritonitis? Follow the steps exactly as taught to you (the

    patient)

    Good Handwashing Wear Mask during exchanges

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    Dialysis)

    PD ( ontinous ycling PeritonealDialysis)

    A machine (cycler) is used to automaticallyperform exchanges during the night

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    Kidne Trans lant

    person into your body.

    surgery

    Disease

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    Kidney from a blood relative (Living Related

    Kidney from a non-blood relative (spouse,

    - A deceased donor kidney from a National

    Trans lant List

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    Why are patients tested? a e sure a oo an ssue ma c

    Make sure that the donor and the recipient

    mentally)

    C C li ti f

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    Common Complications of

    Transplantation

    Surgical complications

    Lymphocele

    Acute rejection

    The immune system sees the transplant as aforeign body and attacks it.

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    Anti-rejection drugs are given-known as

    mmunosuppressan rugs Side effects

    e g ga n

    Hypertension

    Increased chance of Infection Cancer

    A special diet is followed, but not aslimiting as for the In-center Hemopatients

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    blood.

    Three Types of Accesses:

    Fistula

    Graft

    Catheters

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    a vein,

    candidate

    ncourage your pa en o s ar exerc s ngapproximately 1 week after surgery

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    -

    (wrist) and cephalic vein (elbow) Most common

    Brachiacephalic- Brachial artery

    connected to the ce halic vein Transposed Basilic Vein- a deep vein

    brou ht closer to the surface of the skin

    and the vein is moved to the front of theupper arm

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    Radiocephalic Fistula Brachiacephalics u a

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    Fistula

    Advantages Disadvantages

    Less chance of

    Infection

    mature (4-12 wks)

    Slow to develop Stenosis may develop

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    Vascular Access

    ssess e ccess eac rea men

    Look for si ns of infection redness or draina e

    Listen for the bruit (low pitch sound)

    Feel for the thrill (purring or vibrations)

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    -

    hands after access placement. -

    Bruit- swooshing noise; louder if stenosis

    Thrill- continuous vibration; not a strong

    Aneurysm-ballooning or bulging of a blood

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    Keep needles at least 1 inch from

    Avoid curves, flat spots, aneurysms

    Even if the vessel appears large enough

    Gives it a better feel Helps to see the vessel better

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    Arterial needles can be antegrade or

    Venous needles should always be placean egra e owar e oo ow owarthe patient)

    Bevel down-prevents coring

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    -

    you choose 2 new holes Rotate sites to revent aneur sm formation

    Button Hole Techni ue or Constant Site For patients with low pain tolerance

    For atients with limited access areas

    Fewer missed insertions & infiltrations Fewer infections

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    An artificial (synthetic) blood vessel used to connect an

    Advantages Disadvantages

    artery ve n

    Takes less time tomature

    More prone toinfection

    arger areas ocannulate

    Easier to cannulate

    ore prone oThrombosis (clotting)

    More likel to develo

    Used in Diabetics

    a stenosis

    Older Patient

    Patients with Poor

    Circulation

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    -

    subcutaneous portunder the skin

    Reasons for Use

    Acute Renal Failure Peritonitis

    Awaiting a Transplant

    Refuses a permanentaccess

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    Good for urgent use Can be hidden under

    Leads to infection Can cause

    clothing

    Pt able to move more

    inflammation, clotting,and stenosis

    No needles used

    leading to pooradequacy

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    To maintain nutrition

    to a minimum

    Planned for every patient

    n v ua ze

    Can be changed based on patient needs

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    Protein-aids in growth and maintains body, ,

    Sodium-found naturally in foods; cant be

    Potassium-controls & transmits nerveim ulses

    Phosphorus-Major source from the Bones;hel s with ener , absor tion, metabolism offats

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    Little or no urine is produced

    Fluid must be removed through dialysis

    Fluid weight varies between patient

    rea men s

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    -

    restriction Limited to volume of the atients urine out ut+ 1 liter (4 cups/day)

    No urine output- patient is limited to 4 c/day

    Dry Weight-Post dialysis weight at which

    excess fluid has been removed and thepatient is normotensive

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    Teach the effects of Protein oo muc = eva e or ec s a ys s

    treatment time

    Teach the effects of Sodium

    Too little caused by diarrhea or fluid overload

    Too much=Arrhythmias

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    Sources All protein foods (Meat, fish, poultry, eggs)

    Avoid or limit these sources

    Milk and milk products

    Dried beans

    Chocolate

    Cola

    Nuts and seed

    Whole grains

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    Anything that melts at room temperature is

    Never guess when you are talking to yourpa en s a ou e re a e ssues-re erthem to the Dietitian or any nutritional

    an ou s a m g e n your un .

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    CRITICAL THINKING IS KEY!