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1 Medical University of Warsaw Faculty of Medicine - English Division 61 Żwirki i Wigury Street 02-091 Warsaw http: // www.wum.edu.pl/ 2 nd YEAR CURRICULUM 6-year program Warsaw, 2019/2020

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Page 1: 2wl.wum.edu.pl · C Continuous assessment Minimum 60% points from practical classes (Part II) 8. Evaluation criteria Exam MCQ Form of receiving credit in a subject: MCQ grade criteria

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Medical University of Warsaw Faculty of Medicine - English Division

61 Żwirki i Wigury Street 02-091 Warsaw

http: // www.wum.edu.pl/

2nd YEAR CURRICULUM

6-year program

Warsaw, 2019/2020

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SCHEDULE – ACADEMIC YEAR 2019/2020

2nd year 6-year program

WINTER SEMESTER – 01.10.2019 – 16.02.2020

STUDENT’S ACADEMIC CLASSES: 01.10.2019 – 22.12.2020

07.01.2020 – 26.01.2020

WINTER HOLIDAYS: 23.12.2019 – 06.01.2020

EXAM SESSION: 27.01.2020 – 02.02.2020

DAYS OFF BETWEEN SEMESTER: 03.02.2020 – 9.02.2020

RETAKE EXAM SESSION: 10.02.2020 – 16.02.2020

SUMMER SEMESTER – 17.02.2019 – 30.09.2019

STUDENT’S ACADEMIC CLASSES: 17.02.2020 – 11.04.2020

19.04.2020 – 26.04.2020

04.05.2020 – 14.06.2020

EASTER HOLIDAYS: 12.04.2020 – 18.04.2020

SPRING HOLIDAYS: 27.04.2020 – 03.05.2020

EXAM SESSION: 15.06.2020 – 05.07.2020

SUMMER HOLIDAYS: 06.07.2020 – 30.08.2020

RETAKE EXAM SESSION: 31.08.2020 – 6.09.2020

SUMMER HOLIDAYS: 07.09.2020 – 30.09.2020

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Curriculum of 2nd year of 6-year 2019/2020 ED program and the list of contents:

2nd year

page subject form

of credit

semester Total no of hours

including

ECTS lecture seminar class practical

4 Biochemistry with Elements of Chemistry

exam 1&2 180 40 50 90 17

13 Cytophysiology exam 1 45 10 10 25 2

22 Physiology with Pathophysiology

exam 1&2 220 65 65 90 19

35 Immunology exam 2 40 40 3

39 Hygiene and Epidemiology credit 1 30 10 20 2

44 Polish for Medicine credit 1&2 80 80 5

75 Medical Ethics with Elements of Philosophy

credit 1 30 18 12 2

51 Genetics credit 2 25 8 17 2

57 First Aid with the elements of nursing

credit 2 45 9 36 3

Vocational Training credit 2 120 120 4

63 Research Methodology credit 1 30 15 15 1

Optional course credit 1&2 60 60 4

69 Medical Communication credit 2 32 20 12 1

937 153 279 385 120 65

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1. Imprint

Faculty name:

Faculty of Medicine with the English Division and the Physiotherapy

Division, Medical University of Warsaw

Education program (field of study, level

and educational profile, form of studies,

e.g., Public Health, 1st level studies,

practical profile, full time):

English Division, 1st level studies, practical profile, full-time

Academic year: 2019/2020

Module/subject name: Biochemistry with elements of chemistry

Subject code (from the Pensum system): 45734

Educational units:

Chair and Department of Biochemistry,

First Faculty of Medicine

02-097 Warsaw, ul. Banacha 1

Phone: +48 (22) 57 20 693

e-mail: [email protected]

Head of the unit/s: Part 2. Dr hab. Marta Struga

Study year (the year during which the

respective subject is taught):

second year

Study semester (the semester during

which the respective subject is taught):

III and IV semester

Module/subject type (basic,

corresponding to the field of study,

optional):

basic

Teachers (names and surnames and

degrees of all academic teachers of

respective subjects):

dr hab. Marta Struga, dr hab. Michał Skrzycki, , dr Emilia Grosicka-

Maciąg, mgr Beata Chełstowska, dr Magdalena Mielczarek-Puta, dr

Alicja Chrzanowska, dr Dagmara Kurpios-Piec; lek. Wojciech

Graboń, dr Ewa Usarek, lek. Leszek Kraj

Biochemistry with Elements of Chemistry

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ERASMUS YES/NO (Is the subject

available for students under the

ERASMUS programme?):

YES

A person responsible for the syllabus (a

person to which all comments to the

syllabus should be reported)

dr Emilia Grosicka-Maciąg, phone: 22 5720693

Number of ECTS credits: 17

2. Educational goals and aims

Structures, properties and metabolism of substances present in the body: proteins, carbohydrates, lipids, nucleic

acids, vitamins, hormones. Control and integration of metabolic pathways.

Objectives:

1. To develop a solid understanding of the fundamental chemistry 2. To provide an introduction to the principles of biochemistry that gives the students a command of its concepts. 3. To provide an explanation of the relationship between the three-dimensional structure of macromolecules and

their biological activities. 4. To give the insight into understanding how metabolic processes can contribute to explanation of pathological

phenomena. 5. To give the students experience in biochemical methodology in order to appreciate the clinical biochemistry

techniques as diagnostic tools, and to be able to interpret the results for appropriate diagnosis and follow up of patients.

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3. Initial requirements

1. It is beneficial to read and understand the chemical and biological background before the seminars and laboratory classes

4. Learning outcomes corresponding to the subject

A list of course learning outcomes

Symbol of course learning

outcomes Description of course learning outcomes

The reference to

programme learning

outcomes (number)

W1 Water and electrolyte balance in biological systems B.W1

W2 Acid-base equilibrium and mechanism of buffer action

and their importance in organism homeostasis B.W2

W3 Basic reactions of organic and inorganic compounds in

water solutions B.W4

W4 Structure of organic and inorganic compounds present

in cells, extracellular matrix and body fluids B.W10

W5 Structure of lipids and polysaccharides and their roles in

cell structures B.W11

W6

Primary, secondary, tertiary and quaternary structures

of proteins; posttranslational and functional

modifications of proteins and their importance

B.W12

W7 Primary and secondary structures of DNA and RNA B.W13

W8 Stages of expression of genetic information B.W14

W9 Functions of nucleotides B.W13

W10 Basic catabolic and anabolic pathways, how are they

regulated by genetic and environmental factors B.W15

W11 Metabolic profiles of main organs and tissues B.W16

W12 Oxidative stress B.W17

W13

Digestive enzymes, mechanism of HCl production in

stomach, role of the bile in lipids digestion, absorption

of digestive products

B.W18

W14 Mechanism of hormones action B.W26

U1 Calculations of concentrations of solutions (percentage,

molar), calculations of pH and osmolality of body fluids B.U3

U2 Performance of basic laboratory techniques B.U9

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U3 Prediction of direction of metabolic processes in term of

energetic state of cells B.U6

U4 Using databases: internet and searching needed

information B.U11

U5 Planning and performance simple research experiments,

results interpretation, and drawing conclusions B.U14

5. Forms of classes

Form Number of hours Number of groups

Lecture 40 1

Seminar 50 4

Practical classes 90 8

6. Subject topics and educational contents

Lectures:

L1 – Water and electrolyte balance in biological system: Solutions, acids and bases, concept of pH, hydrolysis,

Volumetric analysis – W1

L2 - Basic reactions of inorganic compounds in water solutions, Mechanism of buffer action and their importance in

organism homeostasis, - W2, W3

L3 - Characterization of main groups of organic compounds (hydrocarbons, arenes, alcohols, ethers, carbonyl

compounds, carboxylic acids and their derivatives, amines) isomerism - W3, W4

L4 – Proteins – W6

L5 - Nucleic acids, expression of genetic inforamtion – W7, W8

L6 - Enzymes - W10

L7 – Revisions

L8 - Tissue oxidation - W12

L9-L10 - Carbohydrates metabolism - W10, W13

L11-L12 - Lipids metabolism, lipidoses, atherosclerosis -W10, W13

L13 – Revisions

L14 - Protein turnover, ureogenesis - W10, W13

L15 - Amino acids metabolism - W10

L16 – Blood – W11

L17 - Metabolism of purine and pyrimidine nucleotides - W9

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L18 – Vitamins – W10

L19 – Metabolism in the liver – W11

L20 - Revisions

Seminars:

S1 - Chemical calculations (concentrations) - W1, W2, U1

S2 - Biochemical calculations (buffers) - W1, W2, U1

S3 - Analysis of organic compound and inorganic ions - W3

S4 – Carbohydrates and lipids – W5

S5 – Proteins – W6

S6 – Nucleic acids - W7, W8

S7 – Enzymes – W10

S8 - Tissue oxidation – W11

S9 - S10 – Metabolism of carbohydrates - W10, W13, U3

S11 – S12 – Metabolism of lipids - W10, W13, U3

S13 - Blood - W11

S14 – S15 - Ureogenesis, AAs metabolism - W10, U3

S16 - Metabolism of purines, pyrimidines - W10, U3

S17 -Vitamins – W10

S18 - Metabolism in the liver, biotransformation - W11, U3, U4

Laboratory classes:

C1 - Basic laboratory techniques, acid – base balance in organism, buffers– U1, U2,

C2 - Qualitative analysis of organic compound

C3 - Lipids -chemical properties– W3, U2

C4 – Carbohydrates - chemical properties - W5, U2

C5 - Amino acids and proteins – W3, W4, U2

C6 - Proteins, properties and methods of separation - W6, U1, U2

C7 – Nucleic acids – W7, U5

C8 - Enzymes - U1, U2

C9 - Enzymes - kinetics - U1, U2

C10 - Carbohydrates - U1, U2

C11 - Lipids - U1, U2 .

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C12 - Digestive enzymes - U1, U2

C13- Blood constituents - U1, U2

C14 - Urine constituents - U1, U2

C15 - Biochemistry all around us - U1, U2, U5

7. Methods of verification of learning outcomes

Learning

outcome

corresponding to

the subject

(symbol)

Forms of classes

(symbol)

Methods of verification of

a learning outcome Credit receiving criteria

W1-W14 W Final exam (MCQ 100

questions) At least 55% points

W1-W14 S

Three intermediate

assessment tests during the

year

At least 55% points

W1-W14, U1, U2,

U3,U4,U5 C Continuous assessment

Minimum 60% points from practical

classes (Part II)

8. Evaluation criteria Exam MCQ

Form of receiving credit in a subject: MCQ

grade criteria

2.0 (failed) 0 – 54% of correct answers during final exam. Insufficient

learning outcomes

3.0 (satisfactory) 55 – 64% of correct answers during final exam

3.5 (rather good) 65 – 74% of correct answers during final exam

4.0 (good) 75 – 84% of correct answers during final exam

4.5 (more than good) 85 – 93% of correct answers during final exam

5.0 (very good) 94 – 100 % of correct answers during final exam.

Outstanding effects of education

9. Literature

Obligatory literature:

1. General Chemistry with Qualitative Analysis – Whitten, Davis, Peck, VI ed., Saunders College Publishing, 2000.

2. Introduction to Organic Chemistry – Brown, W.H. Saunders College Publishing, 2000.

3. Biochemistry Lippincott’s Illustrated Reviews, D.R. Ferrier (R.A. Harvey ed.), Wolters Kluwer, Lippincott,Williams & Wilkins,

sixth edition.

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4. Harpers’ biochemistry, R.K. Murray, D.K. Granner, P.A. Mayers, V.W. Rodwell, Appleton & Lange. Last edition.

Supplementary literature:

1. An Introduction to Medicinal Chemistry, L.P. Graham, Oxford University Press, 2009.

2. Biochemistry. L. Stryer, W.H. Freeman & Company, New York.

3. Principles of Medical Biochemistry, G. Meisenberg, W.H. Simmons, Elsevier (online access + interactive extras,

studentconsult.com).

4. Medical Biochemistry, J.W. Baynes, M.H. Dominiczak, Elsevier, (online access + interactive extras,

studentconsult.com). Last edition.

5. Textbook of Biochemistry with clinical correlations, T.M. Devlin, Willey-Liss, Inc. Last edition.

10. ECTS credits calculation

Form of activity Number of hours Number of ECTS credits

Direct hours with an academic teacher:

Lectures 40 2

Seminars 50 4

Practical classes 90 4

Student's independent work (examples of the form of work):

Student's preparation for a seminar 70 3

Student's preparation for a class 40 2

Preparation for obtaining credits 80 4

Other (please specify) ----- -----

370 19

11. Additional Information

Student is obligated to:

- attend all lectures, laboratory classes, seminars and intermediate assessments on time - be prepared and participate in discussions during seminars and laboratory classes.

In case of illness, emergency or other excusable absence student has to contact dr Emilia Grosicka -Maciąg

as soon as possible (no later than within a week).

Excused absences will require either prior approval, written verification or doctor’s certificate.

Unexcused absences may result in failing the entire course of biochemistry.

Each students must be familiar with the rules of the workshop and safety regulations prevailed in the

biochemistry laboratory, undertake to follow them, and sign a proper declaration before the laboratory

classes start.

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Evaluation:

Rules for Biochemistry

http://biochemia.wum.edu.pl

Attendance:

Student is obliged to:

- attend all lecture, laboratory classes, seminars and intermediate assessments on time - be prepared and participate in discussions during seminars and laboratory classes

In case of illness, emergency or other excusable absence student should contact dr Emilia Grosicka -

Maciąg, ([email protected]) as soon as possible (no later than within a week).

Excused absences will require either prior approval, written verification or doctor’s certificate.

Unexcused absences may result in failing the entire course of biochemistry.

Evaluation:

Laboratory classes: students’ knowledge, manual skills, participation and preparedness for the laboratory

are awarded with points (from 1 to 6), and 60% gained points are needed to get the credit (the total: 14

laboratory classes x 6 points =84, and 50 are needed to get the credit) There are no points for the first

laboratory class (no 1).

Written retake from not credited lab/s is taken at the end of the course (in May).

Excused absences may result in the written retake taken at the end of the course (in May).

Seminars: Students can get 1 point for being active during each seminars (18 seminaries, so sum = 18

points). There will be 4 short tests, each test consists 10 questions = 10 points. The total: 18 + 4x10 = 58,

and 29 (50%) are needed to get the credit.

More than 2 absences (in both winter and spring semesters) may result in the necessity of taken the

assessment test from all seminar topics (in May).

Three assessment tests (MCQ) will take place. Short answer essays, matching and structures may be

included. At least 55% of correct answers are needed to pass. Unexcused absence (within a week) means

failing.

The first and the second retake test from each assessment test are in May.

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Student can take the final exam after getting credit

Final exam is composed of multiple choice questions, short answer essays, matching and structures may

be included. At least 55% of correct answers are needed to pass.

Academic honesty: Cheating will not be tolerated! The minimum penalty for cheating will be zero points

for a test or exam.

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12. Imprint

Faculty name: The English Division of the Faculty of Medicine

6-year program

Education program (field of study, level

and educational profile, form of studies,

e.g., Public Health, 1st level studies,

practical profile, full time):

Second year, semester III, full-time program

Academic year: 2019/2020

Module/subject name: Cytophysiology

Subject code (from the Pensum system): 45735

Educational units:

Department of Histology and Embryology

Center for Biostructure Research

02-004 Warszawa, Chałubińskiego 5 Str.(Anatomicum bldg.) Web

site: http://histologia.wum.edu.pl

Department office is open for students on working days.

Business hours 9: 30 - 14: 00, tel/fax 22 629-5282.

Head of the unit/s: Jacek Malejczyk, Ph.D. Professor

Study year (the year during which the

respective subject is taught):

2

Study semester (the semester during

which the respective subject is taught):

1,2

Module/subject type (basic,

corresponding to the field of study,

optional):

basic

Teachers (names and surnames and

degrees of all academic teachers of

respective subjects):

Jacek Malejczyk, Ph.D., Professor

Paweł Włodarski, M.D., D.D.S., Ph.D., Professor

Stanisław Moskalewski, M.D., Ph.D., Professor

Marek Kujawa, M.D., Ph.D.

Anna Hyc, Ph.D., Associate professor

Anna Iwan, Ph.D., Associate professor

Izabela Młynarczuk-Biały, M.D., Ph.D., Associate professor

Łukasz Biały, M.D., Ph.D.

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Ewa Jankowska Steifer, Ph.D.

Izabela Uhrynowska-Tyszkiewicz, M.D., Ph.D.

Justyna Niderla-Bielińska, Ph.D.

Aneta Ścieżyńska, Ph.D.

Artur Kamiński, M.D., Ph.D., Associate professor

Jarosław Jóźwiak, Ph.D., Associate professor

ERASMUS YES/NO (Is the subject

available for students under the

ERASMUS programme?):

YES

A person responsible for the syllabus (a

person to which all comments to the

syllabus should be reported)

Łukasz Biay MD PhD

Number of ECTS credits: 3

13. Educational goals and aims

1. Presentation of processes concerning differentiation regulation and functioning of different cells and their populations;

2. Presentation of the mechanisms of cell cycle, mechanism controlling cell proliferation and effects of their disturbances, often leading to neoplasm formation;

3. Presentation of molecular mechanisms of apoptosis and external signal reception by the cell, signal transduction inside the cell and regulation of intercellular processes;

4. Discussion of current views on cell ageing and demonstration why neoplastic cells are thought to be immortal;

5. Presentation of basic histochemical and immunocyteochemical methods used in modern microscopic diagnosis;

6. Presentation of methods for conservation of tissues harvested for grafting for therapeutic purposes and discussion of functioning of such grafts in the organism.

7. Presentation of basic molecular biology and basic molecular research methods used in modern medical diagnosis.

14. Initial requirements

Credit in histology and embryology.

Knowledge of cell biology, molecular biology and biochemistry from other curses for the study.

A.W1; A.W4; A.W5; A.W6; A.U1; A.U2; A.U5.; B.W18; B.W27.

15. Learning outcomes corresponding to the subject

A list of course learning outcomes

Symbol of course

learning outcomes Description of course learning outcomes

The reference to

programme

learning outcomes

(number)

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W1

The student knows the physicochemical and molecular basis of

the functioning of sensory organs

B.W7

W2

Student knows the structure of lipids and proteins, as well as their

function in cellular and extracellular elements

B.W11

W3

The student knows the functions of nucleotides in the cell, the

structure of I and II DNA and RNA, and the structure of chromatin

B.W13

W4

The student knows the functions of the genome, transcriptome

and human proteome and the basic methods used in their study;

describes the processes of replication, repair and recombination

of DNA, transcription and translation, and degradation of DNA,

RNA and proteins; knows the concepts of gene expression

regulation

B.W14

W5

The student knows the methods of communication between cells,

as well as between the cell and the extracellular matrix, and the

signaling pathways in the cell and examples of disorders in these

processes leading to the development of cancer and other

diseases

B.W21

W6

The student knows processes such as: cell cycle, proliferation,

differentiation and aging of cells, apoptosis and necrosis, and their

importance for the functioning of the body

B.W22

W7

The student knows in a basic scope the issue of stem cells and

their applications in medicine

B.W23

W8

The student knows the mechanism of action of hormones and the

consequences of disorders of hormonal regulation

B.W26

W9 The student knows the mechanisms of aging of the body

B.W28

W10

The student describes the structure of chromosomes and the

molecular basis of mutagenesis

C.W4

U1

The student is able to plan simple research in the field of

cytophysiology and to interpret the results and draw conclusions

B.U14.

16. Forms of classes

Form Number of hours Number of groups

Lecture 10 1

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Seminar 10 5

Practical classes 25 10

17. Subject topics and educational contents

Lectures:

W1 General aspects of cytoplasmic processes (B.W11; B.W.17) Łukasz Biały, M.D., Ph.D

W2 General aspects of cell nucleus function. (B.W.14) Jarosław Jóźwiak, Ph.D., Associate professor

W3 General aspects of cell communication. (B.W.21; B.W.17) Anna Iwan, Ph.D.

W4 Selected cell signaling events. (B.W.21; B.W.26) Jacek Malejczyk, Ph.D., Professor

W5 General aspects of cell divisions (B.W.21; B.W.22) Justyna Niderla-Bielińska, Ph.D.

W6 General aspects of cell death. (B.W.22) Anna Hyc, Ph.D

W7 General aspects of Cell differentiation. (B.W.22) Ewa Jankowska Steifer

W8 Cancer cell (C.W.4) Łukasz Biały, M.D., Ph.D.

W9 Cancer biology. (B.W.21, B.W.22) Izabela Młynarczuk-Biały M.D., Ph.D.

W10 Stem cell. (B.W.28) Marek Kujawa, M.D., Ph.D

– seminars – 1 hour; C – Practical class – 2 hours (C11 – 3 hours);

S1. Structure and function of cytoplasm and cell membranes. (B.W11; B.W.17) Łukasz Biały, M.D., Ph.D.

Physiology of cell membranes. Structure of lipids and their function In the cell and extracellular matrix. Lipids rafts.

Caveolae. Asymmetry of the plasma membrane. Cellular transport. Glucose transporters. ABC transporters and

MDR phenomenon.Physicochemical amd molecular aspects of of perception of the organ of the hearing.

C1. Physiology of selected cytoplasmic processes. (B.W11; B.W.17)

Physiology of membrane enclosed compartment. Physiology of selected cytosolic processes. Ribosomes,

Polisomes. Endo and exocytosis pathways. Interactions between cells and extra-cellar matrix. Cytoskeleton.

S2. Cytophysiology of Cell nucleus and function. (B.W.14) Jarosław Jóźwiak, Ph.D., Associate professor

Structure of the cell nucleus. Structure of chromatin and its modifications. Tissue specific modifications of chromatin.

Transcriptional activity of chromatin. RNA interference Chromosomes. Telomers. Nuclear structures involved in

RNA processing.

C2. Structure of nucleus. (B.W.14; C.W.4)

Nucleolus- structure and function. Nuclear envelope and nuclear-cytoplasmic transport. Nuclear processes before

cell division. RNA interference.

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S3. Cell to cell communication. (B.W.21; B.W.17) Anna Iwan, Ph.D.

Types of communication between cells in the human body. The answer of cells to extracellular stimuli. Molecular

basis of sense perception and signal transmission in receptor cells.

C3. Cell signalling – intracellular pathways. (B.W.21)

Receptors, second messengers (cAMP, cGMP, Ca2+. IP3, DG at al.), transcription factors (general and specific –

ie. CREB, AP-1, NFkB ). Structure and function of G-proteins. Receptor and non-receptor tyrosine kinases.

Kinases Src, Jak. MAP, Akt, PI3K pathways.

S4. Cell signalling events. (B.W.21; B.W.26) Jacek Malejczyk, Ph.D., Professor

Cell signalling by selected hormones, cytokines, growth factors and extra-cellar matrix components. Pathways

activated by insulin, steroid hormones, nitric oxygen.

C4. Clinical aspect of cell signalling. (B.W.21; B.W.26)

Abnormalities in the cell signalling in human diseases. Cell signalling pathways as a therapeutic target.

S5. Cell proliferation. (B.W.21; B.W.22) Justyna Niderla-Bielińska, Ph.D.

Types of cell division; mitosis, meiosis. Cell cycle. Structure and function of mitotic spindle. Karyo- and cyto- kinesis.

C5. Regulation of the cell cycle. (B.W.22).

Cyklins i CDKinases. Role of p53, p21. pRb, Cdc25, Cdc6, APC-complex. Action of drugs interfering with cell

division.

S6. Cell senescence and aging. (B.W.22; B.W 28) Anna Hyc, Ph.D.

Cellular senescence. Replication senescence. Cell death: apoptosis, necrosis and other types of cell death.

C6. Cell death. (B.W.22)

Apoptotic pathways. Execution of apoptosis. Caspases. Apoptosis without caspases. Physiological apoptosis.

Apoptosis induction as a therapeutic target. Methods of detecting of apoptotic cells.

S7. Cell differentiation. (B.W.22) Ewa Jankowska Steifer, Ph.D.

Mechanism of cell differentiation. Genes involved in Cell differentiation. Epigenetic mechanisms. Cell differentiation

during embryogenesis and tissue regeneration.

C7 Stem cells.

Cell potency. Stem cells, progenitor cells. Cell differentiation of stem cells in the human body.

S8. Mechanisms of oncogenesis. (C.W.4) Łukasz Biały, M.D., Ph.D.

Protective cellular mechanisms against cancer transformation. Abnormal gene expression in cancer. Role of p53,

p21, Rb, onco mi-RNA. ATM/ATR, BRCA1/2.

C8 Caner transformation. (C.W.4)

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Malignant transformation on the example of retinoblastoma, colon cancer, breast cancer, lung cancer, chronic

myeloid leukaemia.

S9. Cancer cell biology - selected topics. (B.W.21, B.W.22) Łukasz Biały, M.D., Ph.D.

Cancer cells properties. Abnormalities in cellar processes in cancer cells. Abnormal cell growth. Models of cancer

evolution. Cancer stem cell theory. Tumor progression. Tumor angiogenesis. Cancer cell – extracellular matrix

interactions and metastasis.

C9 Molecular cancer therapy. (B.W.21, B.W.22)

Cellular target of anticancer drugs incl. molecular targets of novel drugs in oncology.

S10. Regenerative medicine and tissue bio- engineering. (B.W.28) Marek Kujawa, M.D., Ph.D.

Cells in regenerative medicine. Stem cells – embryonic and somatic. Differenciated cells: autologenic, izogenic

(syngenic), allogenic, xenogeneic, primary and secondary. Method of stem generation: embryonic, somatic and

induced stem cells. Therapeutic cloning.

C10. Cell therapy. (B.W.28)

Stem cell therapy possibilities in clinical usage.

C11. Methods of cell culture and techniques used in the medical research. ( B.U.14) Anna Hyc, Ph.D.

Methods of cell culture for medical research and regenerative medicine. The in vitro experiment on cell cultures.

Types of the cell cultures. Cytostatic/cytotoxic tests in a drug discovery. Laboratory methods of cell research in

medicine.

C12. Tissue and cell banking for medical proposes. (B.W.14; B.W.28) and crediting to the final exam

Rules of tissue and cell banking. Qualification of donors of tissues and cells. Organisation of tissue and cell

banking in Poland, EU at the word. Types of transplantation. Clinical usage of transplants. Coordination 2f tissue

and cell transplantation. Advanced technology medical products (ATPM) in tissue and cell banking. Types of the

scaffolds and cells in tissue engineering. Transplantation in a regenerative medicine.

18. Methods of verification of learning outcomes

Learning outcome

corresponding to

the subject

(symbol)

Forms of

classes

(symbol)

Methods of verification of

a learning outcome Credit receiving

B.W7

Lectures /

Seminars /

Practical

classes

Examination by the class teacher

and the final exam

A minimum of 60% of correct

answers

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B.W11

Lectures /

Seminars /

Practical

classes

Examination by the class teacher

and the final exam

A minimum of 60% of correct

answers

B.W13

Lectures /

Seminars /

Practical

classes

Examination by the class teacher

and the final exam

A minimum of 60% of correct

answers

B.W14

Lectures /

Seminars /

Practical

classes

Examination by the class teacher

and the final exam

A minimum of 60% of correct

answers

B.W21

Lectures /

Seminars /

Practical

classes

Examination by the class teacher

and the final exam

A minimum of 60% of correct

answers

B.W22

Lectures /

Seminars /

Practical

classes

Examination by the class teacher

and the final exam

A minimum of 60% of correct

answers

B.W23

Lectures /

Seminars /

Practical

classes

Examination by the class teacher

and the final exam

A minimum of 60% of correct

answers

B.W26

Lectures /

Seminars /

Practical

classes

Examination by the class teacher

and the final exam

A minimum of 60% of correct

answers

B.W28

Lectures /

Seminars /

Practical

classes

Examination by the class teacher

and the final exam

A minimum of 60% of correct

answers

C.W4

Lectures /

Seminars /

Practical

classes

Examination by the class teacher

and the final exam

A minimum of 60% of correct

answers

B.U14.

Lectures /

Seminars /

Practical

classes

Examination by the class teacher

and the final exam

A minimum of 60% of correct

answers

19. Evaluation criteria

Form of receiving credit in a subject: Written exam MCQ test

grade criteria

2.0 (failed) Up to 59% - insufficient grade, no credit

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3.0 (satisfactory) 60 – 68%

3.5 (rather good) 69 – 76%

4.0 (good) 77 – 84%

4.5 (more than good) 85 – 92%

5.0 (very good) 93 – 100%

20. Literature

ED Textbooks:

Basic Course Textbooks:

Essential Cell Biology by. Alberts at all (ed.)

Medical Cell Biology by Goodman (ed.)

Rewiew:

Cell and Molecular Biology Lippincott’s illustrated Review by Chandar, Viselli

Full Text Books:

Molecular Cell Biology by Albers et all (ed.)

Cell Biology by Karp

-The cell – a molecular approach by Cooper, Hausman

21. ECTS credits calculation

Form of activity Number of hours ETCS number

Direct hours with an academic teacher:

Lectures 10

2 Seminars 10

Practical classes 25

Student's independent work (examples of the form of work):

Student's preparation for a

seminar 15 0,5

Student's preparation for a

class 15 0,5

Total 75 3

22. Additional Information

Regulations of classes in Cytophysiology for students of medicine Organization of classes

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1.The classes begin with a seminar part where presence is obligatory. 2. Presence on practical classes and seminars is obligatory. Delays exceeding 15 minutes will be treated as absence. 3. Students enter the classes prepared essentially. The scope of material for classes is given in the "Program of classes". 4. Preparation of students for classes is assessed by the teacher. 5. During the classes, students answer questions, discuss issues covered by the subject of classes and view microscopic preparations, diagrams and electronograms. Presence and passing of classes 1. The condition for crediting is participation in classes and seminars and passing all classes. 2. The condition for passing the class (practical and seminar) is the presence on both parts of the class and obtaining a positive assessment of the knowledge of the material provided for the given occupation in the person conducting the practical part. 3. The days in which the dates of the classes are set are the days of obligatory classes. 4. Due to the character and organization of seminars and practical classes there is no possibility to make up for absences. Absence at 3 or more classes, regardless of the reason, results in not getting a credit for the semester, hence student will not be admitted to the examination. Credit and exam 1. The condition of passing the subject and admission to the exam is passing all the classes. 2. The final exam takes the form of a test. 3. The criteria for passing the exam are determined by the Head of the Department after the test, but it is assumed that at least 60% of the correct answers in the test are required. 4. All reservations regarding the questions of the exam should be submitted by the student in the written form to the members of the Examination Team immediately after the completion of the exam ("Regulations of the Written Examination of the Medical University of Warsaw", point 16). 5. In the case of absence from the exam caused by health reasons, the student is required to provide a medical certificate within three working days of the date of the examination, under pain of entering the unsatisfactory grade. 6. In the event of failing the retake examination, at the student's request, the dean may set a board examination. ________________________________________ Position of the Chair regarding cheating during examinations Cheating on examinations is a breach of ethics and Regulations of Studies at the Warsaw Medical University. Person actively or passively participating in cheating shall be punished by being expelled from the examination and receiving a failing mark. On the top of that, the Department shall institute disciplinary procedure against the cheating students. Person actively participating in cheating is the one, who copies results from other students or uses illegal notes or electronic devices to communicate or store data. Bringing such devices to examinations is forbidden. Passive participation in cheating means allowing other students copy one’s own responses. Thus, a student is obliged to behave honestly, not to allow other students copy his/her own responses. Head of the Department obliges students and examiners to strictly obey these regulations Position of the Chair regarding the form of crediting Students, for ED program are subject to the same criteria as Polish-speaking students and pass tests and examinations in the form of test. Position of the Chair on the form of passing the subject

Students for whom the Polish language is a foreign language are subject to the same assessment criteria as Polish-speaking

students and pass tests and exam in the form of a test.

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23.

Faculty name: Medical Faculty with English Division

Education program (field of study, level

and educational profile, form of studies,

e.g., Public Health, 1st level studies,

practical profile, full time):

medicine, master degree, practical profile, full time

Academic year: 2019/2020

Module/subject name: Physiology with pathophysiology elements

Subject code (from the Pensum system):

Educational units: Chair and Department of General and Experimental

Pathology

Head of the unit/s: Prof. Dariusz Szukiewicz, MD, PhD

Study year (the year during which the

respective subject is taught):

2

Study semester (the semester during

which the respective subject is taught):

3 and 4

Module/subject type (basic,

corresponding to the field of study,

optional):

basic

Teachers (names and surnames and

degrees of all academic teachers of

Prof. Dariusz Szukiewicz, MD, PhD, Katarzyna Romanowska-

Próchnicka MD, PhD, Grzegorz Szewczyk MD, PhD, Aleksandra

Stangret MPT, PhD, Mateusz Wątroba MD, PhD, Joanna

Physiology with Pathophysiology

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respective subjects):

Gołębiewska, MD, PhD, Anna Płatek MD, Przemysław Rzodkiewicz

PhD, Szymon Szczepanik MD, PhD

ERASMUS YES/NO (Is the subject

available for students under the

ERASMUS programme?):

Yes

A person responsible for the syllabus (a

person to which all comments to the

syllabus should be reported)

Grzegorz Szewczyk MD, PhD

Number of ECTS credits: 19

24. Educational goals and aims

8. Explain physiological mechanisms by applying basic principles of physics and chemistry

9. Describe the fundamental mechanisms underlying normal function of cells, tissues, organs, and organ systems of the human body, commensurate with the requirements for a physician providing primary care to patients.

10. Explain the basic mechanisms of homeostasis by integrating the functions of cells, tissues, organs, and organ systems.

11. Apply knowledge of functional mechanisms and their regulation to explain the pathophysiology underlying common diseases.

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25. Initial requirements

2. Knowledge of anatomy

3. Knowledge of histology

4. Knowledge of cell biology

26. Learning outcomes corresponding to the subject

A list of course learning outcomes

Symbol of course learning

outcomes

Description of course learning outcomes

The reference to

programme learning

outcomes (number)

W1

to know function and regulatory mechanisms of all

organs and systems in human body including:

circulatory system, respiratory system, alimentary

system, urinary system and skin and understand the

relationships between them

B.W25

W2

to know and understand definitions: solubility, Osmotic

pressure, isotony, coloid solutions; to know metabolic

profiles of basic organs and systems

B.W3

W3

to know enzymes involved in digestions, gastrin

secretion, role of bile, process of digestion and

absorption and their pathology

B.W18

W4 to know the implication of malnutriton B.W19

W5 to know the implication of vitamin and minerals

deficiency B.W20

W6

to know the action potential, synaptic transmission,

and maintenance of nerve function, smooth and skeletal

muscles function and blood function

B.W24

W7 to know hormones function and the implication of their

dysregulation B.W26

W8 to know aging processes B.W28

W9 to know the relationship between dysregulating factors

and physiological and pathophysiological changes B.W30

W10 to describe water-electrolytes homeostasis in biological

systems B.W1

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W11 to describe acid-base balance, functions of buffer

solutions and their role in homeostasis B.W2

W12 to trace pathological processes, describe their

symptoms and pathogenesis B.W30, C.U.11, E.W7

U1

to describe changes in organism after homeostasis

disturbance, especially after intensive physical effort,

exposure to extreme temperatures, water and blood

loss

B.U7

U2

to perform simple diagnostics tests which are able to

assess human body as a constant regulatory system

(exercise test, etc.) to explain basic test results

(spirometry, ECG etc)

B.U8

U3 to plan and perform basic experiments, explain their

results and put the interpretation B.U14

U4 to explain results of basic clinical examinations and use

the theory in clinical settings C.U11

K1 to understand the need for continuous education D.U16

K2 can cooperate in a team for performing tests, results

interpretation, clinical problems solving and critical

discussion

D.U11

27. Forms of classes

Form Number of hours Number of groups

Lecture 65 1

Seminar 65 4

Practical classes 90 8

28. Subject topics and educational contents

LECTURES

L1- Lecture1- The outline of the subject, the history of physiology and pathophysiology: definition, basic

concepts, the selected profiles of outstanding Polish and foreign physiologists, current place of physiology

and pathophysiology in learning and teaching in medicine. W1

L2- Lecture 2- General Physiology: internal environment of the body, the control of activities of the cell ,

membrane transports -W1,W2,W10

L3- Lecture 3- Cell physiology: structure of the cell membrane Transport, cell cycle, interactions between

cells. Signal transduction in the cell.–W1,W2,W6,W10

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26

L4- Lecture 4- Sensory system. The physiological and pathological pain: definition and classification. Pain

receptors (nociceptors), sensory fibers conductive pain stimuli (quick and slow pain). signal transduction of

pain. Opioid receptors. The inhibition of pain at the level of the nociceptors. The inhibition of pain on the

level of the spinal cord. W1,W6,W9,W12

L5- Lecture 5- Receptor stimuli and the receptors, the distribution of receptors, receptor properties, coding

information, exsteroreceptors, interoreceptors, proprioceptors, motor nerves innervation receptors - W1,W6

L6- Lecture 6- Autonomic nervous system: Organization of the autonomic nervous system (ANS). Efferent

way in ANS. Effectors, function and distribution of ANS. Neurotransmitters of sympathetic and

parasympathetic parts ANS. Clinical evaluation of ANS dysfunction in extrapyramidal diseases.- W1,W6,W7

L7- Lecture 7- The circulatory system – electrical activity of the heart, cardiac arrythmias- W1,W6,W9,W12

L8- Lecture 8- The circulatory system: cardiac muscle mechanics and cardiac pump, hemodynamics, venous

return and cardiac output, regulatory mechanism of blood pressure, regulation of tissue blood flow -

W1,W6,W9,W12

L9- Lecture 9- physiology of physical effort: The importance of physical activity. The influence of physical

exercise on the body. Classification and evaluation of physical efforts. The impact of training on human

athletic performance. - W1,W9,W12

L10- Lecture 10- Skeletal muscle physiology, Classification of muscle fibers. The structure of the muscle

fibers. Structural differences in skeletal muscle, smooth muscle and myocardial cells. Energy of ATP, the

role of ATP, Types of proteins in the sarcomere. the role of dystrophin. Duchenne and Becker dystrophy.

Miopathy. disturbance of neuro-muscular junction: types of ACh receptors, pathways of Ach metabolism,

miasteny, Lambert-Eaton syndrome- W1,W6,W9,W12

L11-Lecture 11- Kidney function. Renal blood flow and glomeruli filtration, role of kidneys in homeostasis,

reabsorbtion processes in proximal tubule, Henle’s loop, distal tubule and collecting ducts.

W1,W2,W9,W10,W11

L12- Lecture 12- Respiratory system: function of respiratory system, O2 and CO2 transport and diffusion,

gas exchange, control of respiratory pattern, ventilation/perfusion, central and peripheral respiratory centres-

W1,W9,W11

L13- Lecture 13- Blood: composition of plasma and morphological elements of blood, hematopoesis, blood

groups, hemostasis - W1,W6,W9

L14- Lecture 14- Gastrointestinal system: secretion, digestion and absorption. liver function -

W1,W3,W4,W5,W9,W12

L15- Lecture 15- Physiology of pregnancy: fertilization, pregnancy and fetal development - W1,W7,W9

L16- Lecture 16- Endocrine system: male and female reproductive system. W1,W7

L17- Lecture 17- Rheumatic diseases: pathophysiology of rheumatic arthritis, systemic lupus erythematosus,

antiphospholipid syndrome, sclerosis, polimyositis, Sjogren syndrome, VasculitisW1,W9,W12

L18- Lecture 18- Pathogenesis of allergic reactions W1,W9,W12

L19- Lecture 19- Inflammatory process as a part of protection strategy. Basic schema of inflammatory

process. Adhesive proteins on the circulating blood cells and on epithelium. Chronic inflammatory

process.W1,W9, W12

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L20- Lecture 20- Dietary dysfunctions. Malnutrition. Vitamin deficiencies. Obesity

W1,W3,W4,W5,W9,W12

L21- Lecture 21- Respiratory system diseases: cystic fibrosis, COPD, astma, sarcoidosis. W1,W9,W12

L22- Lecture 22- Pathophysiology of cardiovascular system: heart insufficiency, cardiac infarction –

patogenesis and symptoms. W1,W6,W9,W12

L23- Lecture 23- Pathology of pregnancy: infertility, induction of fetal malformations, miscarriage and

preterm delivery, preeclampsia, diabates in pregnancy, IUGR W1,W7,W9,W12

L24- Lecture 24- Aging: predisposal aging factors, different types of stress, thermodynamic theory, selected

aspect of aging. W1,W8,W9,W12

L25- Lecture 25- Biology of cancer. Epidemiology. Definition of oncogens and suppressor genes.

Angiogenesis. Inherited predisposition for cancer. Carcinogens. W1,W9,W12

SEMINARS

S1- Seminar 1- Cell physiology: Membrane transport, cell cycle, Signal transduction. W1,W2,W6,W10,K1

S2- Seminar 2- Sensory physiology: Eye as an optical system. Stimulation of photoreceptors. Adaptation of

the eye to the world and the dark. Color vision. The field of vision (Stereopsis). Vegetative innervation of

the eye (the eye pupil width accommodates). Refractive eye (myopia, hyperopia, astigmatism). Losses in

the field of view. Stereoscopic vision disorders. The sense of hearing and balance. The construction of the

outer ear, middle ear, inner ear. The conduction way of the sounds. The method of hearing tests

(audiometry). Causes of hearing loss. Gustatory and olfactory system -W1,W6,W9,K1

S3- Seminar 3- Nervous system I Neurophysiology; organisation of nervous system, sensory receptors,

the motor neurons of the spinal cord and brainstem, sensory and motor pathways that control the

functions of upper and lower motor neurons of the spinal cord. Classification of sensory stimuli.

transformation of sensory stimulus to electrical signal. Classification of sensory fibres. Somatic sense. The

classification of receptors, the structure and mechanism of action of sensory receptors, temperature,

deep surface sensation. extero and proprioceptive feeling pathways, Centers of the cerebral cortex,

sensory integration. The Organization of motor cortex neurons and connections with other areas of the

cerebral cortex stages of creating movement. Efferent motor pathways. The role of cerebellum.. - -

W1,W6,W9,K1

S4- Seminar 4- Nervous system II: Action Potential, Synaptic Transmission, and Maintenance of Nerve

Function: specificity of neurons, neurotransmitters, ion channels, excitatory postsynaptic potential and

inhibitory postsynaptic potential. modulation of synaptic transmission- -W1,W6,W9,K1

S5- Seminar 5- Smooth muscles: differences between smooth and skeletal muscles, regulation of smooth

muscles activity, the role of calcium in smooth muscles cells contractions-W1,W6,W9,K1

S6- Seminar 6- Higher cognitive skills: memory, speech, limbic system and emotions, W1,W6,W7,W9,K1

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S7- CREDIT 1 - W1,W2,W6,W7,W9,W10,W12,U1

S8- Seminar 8- Cardiovascular system I: Spontaneous heart activity, the effect of epinephrine,

norepinephrine, ACh, propranolol, atropine, cardiac glicosides and calcium channel inhibitors. Generation

of cardiac action potentials. Polarization and repolarization. Effect of autonomic innervation.

W1,W2,W6,W7,W9,U1,K1-

S9- Seminar 9- Cardiovascular system II: Physical and electrophysical basics of ECG.

W1,W2,W6,W7,W9,U1,K1

S10- Seminar 9- Cardiovascular system III: Cardiac cycle phases. Basic hemodynamics parameters. Preload

and afterload. Bowditch’s effect. Frank-Starling law. Systemic circulation. Systolic, diastolic and mean blood

pressure. Total peripheral resistance. The rules of blood flow within vessels, turbulent and laminar blood

flow. Innervation of blood vessels- W1,W2,W6,W9,U1,K1

S11- Seminar 10- Physical effort physiology I: The kinetics of changes in cardiovascular parameters in

response to physical effort..-W1,W6,W9,U1,K1

S12- Seminar 11- Physical effort physiology II: Methods for the assessment of dynamic muscles activity. ECG

during stress test. Respiratory responses to exercise. W1,W6,W9,U1,K1

S13- Seminar 13- Skeletal muscles. Structure of skeletal muscles – molecular basis of muscles contractions.

Electro-mechanical coupling. Regulation of power of contractions. Mechanics of skeletal muscles

contraction. Isotonic/isometric contraction. Metabolism of skeletal muscles. W1,W6,W9,U1,K1

S14- Seminar 14- Respiratory system. Ventilation and the mechanism of breathing. Gas transfer and

transport. W1,W6,W9,U1,K1

S15- CREDIT II -W1,W2,W6,W7,W9,U1

S16- Seminar 16- Blood I: Function of blood. Serum proteins function. Erytropoesis. Hemoglobine – ferrum

metabolism, types of Hgb, oxyhemoglobin equilibrium curve, CO2 transportation. Blood groups. WBC – role

of cytokines, classification, thrombocytes. Hemostasis. W1,W2,W6,W9,W10,U1,K1

S17- Seminar 17- Blood II: Anemias, leucopenias, leucocytoses. Proliferative disorders. W1,W6,W9,U1,K1

S18- Seminar 18- Hormones I : definition of hormones, classification according to structure, regulation of

hypophysis activity. Hormones of the anterior pituitary lobeW1,W6,W7,W9,U1,K1

S19- Seminar 19- Acid – base balance. Respiratory and metabolic disorders.

W1,W2,W6,W9,W12,W12,U1,K1

S20- Seminar 20- Hormones II: Incretine activity - GIP, glucose-dependent insulinotropic polypeptide and

GLP-1, glucagon-likepeptide 1 - W1,W6,W7,W9,U1,K

S21- Seminar 21- Gastrointestinal physiology: Motility of gastrointestinal tract, digestion and absorption.

Liver function. Neurohormonal regulation of food intake. W1,W2,W3,W4,W5,W9,U1,K1

S22- Seminar 22- Electrolytes (K, Na, Ca, Mg): The volume and composition of cellular and extracellular

compartments. Osmolality of body fluids. the regulatory mechanisms of cell volume, water and electrolytes

transportation. Disturbances in electrolytes concentration. W1,W2,W4,W7,W9,W10,U1,K1

S23- Credit III - W1,W2, W3,W4,W5,W6,W7,W9,W10,U1

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S24- Seminar 24- Pathophysiology of cardiovascular system: ischemic heart disease, atherosclerosis, heart

infarction, pathogenesis of different cardiovascular symptoms: dyspnea, cyanosis etc.

W1,W6,W9,W12,U1,U4,K1

S25- Seminar 25- Pathophysiology of reproductive system: infertility: hormonal, tubal and uterine reasons.

Endometriosis, Immunological diseases in reproductive system. W1,W7,W9,W12,U1,U4,K1

S26- Seminar 26- Renal insufficiency: Pathogenesis of prerenal, renal and postrenal insufficiency.

Complication of acute and chronic disease. W1,W7,W9,W10,W12,W12,U1,U4,K1

S27- Seminar 27- Pathophysiology of endocrine system: pituitary, thyroid gland hyper and hypofunction,

adrenal glands – glucorticoids. W1,W7,W9,W10,W12,W12,U1,U4,K1

S28- Seminar 28- Oedema: pathogenesis of different types of oedemas.

W1,W2,W3,W4,W5,W6,W7,W9,W10,W12,U1,U4,K1

S29- Seminar 29- Nervous system pathophysiology W1,W6,W7,W9,W12,U1,U4,K1

S30- Credit IV - W1,W2,W3,W4,W5,W6,W7,W9,W10,W12,W12,U1,K1

Classes

C1- Class 1- Ion channels: Simpatch- measurements of Ion channel electrical activity with patch clamp

method. - W1,W6,W9,U3,K1,K2

C2- Class 2- Sensory system: examination of superficial sensations: touch (light and deep pressure), pain,

and temperature. Examination of pupillary reflexes to the light, examination of air and bone conduction.

W1,W6,W9,U1,U2,K1

C3- Class 3- Nervous system physiology: Examination of the reflexes to discover the level of peripheral

neuron damage. (knee reflex, Achilles tendon reflex). Basic of neurological examination. W1,W6,W9,

U1,U2,K1

C4- Class 4- Neuron: SimNerv – examination of action potential in relationship to the stimulus. The

threshold for nerves activity. Absolute and relative refractory period. W1,W6,W9,U3,K1,K2

C5- Class 5- Smooth muscles: Sim Vessel. Spontaneous and induced smooth muscles activity. The influence

of sympathetic and parasympathetic system. The functional antagonism of different parts of autonomic

nervous system. W1,W6,W9,U3,K1,K2

C6- Class 6- Higher cognitive skills: memory, speech, limbic system and emotions, W1,W6,W7,W9,U1,K1

C7- Credit I - W1,W2,W6,W7,W9,W10,W12,U1

C8- Class 8- Cardiovascular system I: SimHeart . Spontaneous heart muscle activity Cw.2 The effect of

epinephrine Cw.3 Functional antagonism of epinephrine and ACh. Cw.4 The effect of: epinephrine, Ach,

propranolol, atropine, cardiac glicosides and calcium channel inhibitors - W1,W6,W9,U3,K1,K2

C9- Class 9- Cardiovascular system II: Analysis of normal ECG. Sinus rhytm, QRS morphology. Calculation of

electrical axis of the heart. Analysis of basic cardiac arrythmias - W1,W6,W9,U1,U2,U4,K1

C10- Class 9- Cardiovascular system III: Basic diagnostics tools in the assesment of the cardiovascular

system: Hearing of heart sounds, blood pressure measurement.- W1,W6,W9,U1,U2,U4,K1

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C11- Class 10- Physical effort physiology I: The kinetics of changes in cardiovascular parameters in response

to physical effort. W1,W6,W9,U1,U2,K1,K2

C12- Class 11- Physical effort physiology II: Methods for the assessment of dynamic muscles activity. ECG

during stress test. W1,W6,W9,U1,K1

C13- Class 13- Skeletal muscles: Sim Muscle; 1 Single contraction isotonic/isometric; Cw.2 Double

contraction; Cw.3 tetanus contraction- W1,W6,W9,U3,K1,K2

C14- Class 14- Respiratory system: Spirometry – measurements of VC, FEV.- W1,W6,W9,U1,U2,K1,K2

C15- Credit II -W1,W2,W6,W7,W9,U1

C16- Class 16- Blood I: the assessment of blood smear parameters and coagulation, calculation of GFR

(Cockroffa-Gaulta equation - MDRD)- W1,W2,W6,W9,W10,U1,U2,U4,K1

C17- Class 17- Blood: interpretation of selected electrolytes levels and biochemical test in some physiological

fluids - W1,W6,W9,U1,U2,U4,K1

C18- Class 18- Hormones I: fT3, fT4 – their metabolic effect, excess and deficiency; cortisol – function, excess

and deficiency; calcium and phosphate metabolism- W1,W6,W7,W9,U1,U2,U4,K1

C19- Class 19- acidosis, alkalosis: the assessment of kidney function on the base of creatinine clearance. GFR

calculation W1,W2,W9,W12,W12,U1,U2,U4,K1

C20- Class 20- Endocrine and exocrine function of the pancreas. Diabetes. Glucose level measurement.

Analysis of clinical cases. W1,W6,W7,W9,U1,U2,U4,K1

C21- Class 21- Extremal conditions: high altitude, Monge disease, decompression, the effect of acceleration

on human body. Jet-lag effect- W1,W6,W9,U1,K1

C22- Class 22- Kidneys: the composition of urine, creatinine clearence, hormonal and neural regulation of

kidneys filtration, role of the kidneys in regulation of blood pressure. Interpretation of urine analysis.

W1,W2,W4,W7,W9,W10,U1,U2,U4,K1

C23- Credit III - W1,W2, W3,W4,W5,W6,W7,W9,W10,U1

C24- Class 24- Pathophysiology of cardiovascular system: analysis of clinical cases of patients with: IHD,

arterial hypertension and heart abnormalities -W1,W6,W9,W12,U1,U2,U4,K1

C25- Class 25- Reproductive system – analysis of selected reasons of infertility

W1,W7,W9,W12,U1,U2,U4,K1

C26- Class 26- Shock: definition, reasons and pathogenesis, ways of compensation,

complications.W1,W7,W9,W10,W11,W12,U1,U2,U4,K1

C27- Class 27- Pathophysiology of endocrine disorders: Graves disease, Addison’s disease, acute adrenal

gland insufficiency - W1,W7,W9,W10,W11,W12,U1,U2,U4,K1

C28- Class 28- Pathophysiology of the respiratory system: Disorders in ventilation mechanism (restriction,

obturation), analysis of spirometry results. W1,W9,W12,U1,U2,U4,K1

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C29- Class 29- Liver insufficiency: pathogenesis in different etiological factors, increased portal pressure.

Jaundice. W1,W2,W3,W4,W6,W7,W9,W10,W12,U1,U2,U4,K1

C30- Credit IV W1,W2,W3,W4,W5,W6,W7,W9,W10,W11,W12,U1,U4,K1

29. Methods of verification of learning outcomes

Learning

outcome

corresponding to

the subject

(symbol)

Forms of classes

(symbol)

Methods of verification of

a learning outcome

Credit receiving criteria

W1

L:1-25;

S:1-30;

C:1-30.

credit

Exam

presence at all lectures, seminars,

classes, positive mark from credits

and exam

W2

L:2,3,11;

S:1,7-10,15,16,19,21-

23,28,30;

C:7,15,16,19,22,23,29,30

credit

Exam

presence at all lectures, seminars,

classes, positive mark from credits

and exam

W3

L:14,20;

S: 21,23,28,30;

C:23,29,30.

credit

Exam

presence at all lectures, seminars,

classes, positive mark from credits

and exam

W4

L:14,20;

S: 21,22,23,28,30;

C:22,23,29,30.

credit

Exam

presence at all lectures, seminars,

classes, positive mark from credits

and exam

W5

L:14,20;

S: 21,22,23,28,30;

C:22,23,29,30.

credit

Exam

presence at all lectures, seminars,

classes, positive mark from credits

and exam

W6

L:3,4-8,10,13,21

S:1-20,22-24,28-30

C:1-21,23,24,29,30

credit

Exam

presence at all lectures, seminars,

classes, positive mark from credits

and exam

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32

W7

L:6,15-19,23

S:6-9,15,18,20,22,23,25-

30

C:6,7,15,18,20,22,23,25,

27,29,30

credit

Exam

presence at all lectures, seminars,

classes, positive mark from credits

and exam

W9 L:20

credit

Exam

presence at all lectures, seminars,

classes, positive mark from credits

and exam

W9

L:4,7-15,17-25

S:2-30

C:1-30

credit

Exam

presence at all lectures, seminars,

classes, positive mark from credits

and exam

W10

L:2,3,11

S: 1,7,16,22,23,26-30

C:7,16,22,23,26,27,29,30

credit

Exam

presence at all lectures, seminars,

classes, positive mark from credits

and exam

W11

L:11,12

S:19,26,27,30

C: 19,26,27,30

credit

Exam

presence at all lectures, seminars,

classes, positive mark from credits

and exam

W12

L: 4,7-10,14,21-25

S:7,19,24-30

C:7,19,24-30

credit

Exam

presence at all lectures, seminars,

classes, positive mark from credits

and exam

U1 S:7-30

C:2,3,6,7,9-30

active participation in

discussion, credit, exam

active participation during seminars

and classes, positive mark from

credits and exam

U2 C:2,3,9-11,14-20,22,24-

29 active participation in classes

active participation during seminars

and classes

U3 C: 1,4,5,8,13 active participation in classes active participation during classes

U4 S:24-30

C:9,10,16-20,22,24-29 active participation in classes

active participation during seminars

and classes

K1 S:1-30

C:1-30

preparation to semianars and

classes

active participation in

discussion during seminars

active participation during seminars

and classes

K2 C: 2,4,5,8,11,13,14 active work in subgroups

during classes active participation during classes

30. Evaluation criteria

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Form of receiving credit in a subject:EXAM

grade criteria

2.0 (failed) not completing the receiving criteria or getting 50%

and less of possible points during the exam.

3.0 (satisfactory) getting more than 50% of possible points during the

exam

3.5 (rather good) On the basis of an analysis of the distribution of

exam results

4.0 (good) On the basis of an analysis of the distribution of

exam results

4.5 (more than good) On the basis of an analysis of the distribution of

exam results

5.0 (very good) On the basis of an analysis of the distribution of

exam results

31. Literature

Obligatory literature:

Rodney A. Rhoades, David R. Bell : Medical physiology : principles for clinical medicine — 2013, 4th ed. Wolter’s Kluwer

Gary D. Hammer, MD, PhD, Stephen J. McPhee, MD, Pathophysiology of Disease: An Introduction to Clinical Medicine, 2014, 7e, McGraw Hill.

Supplementary literature:

John E. Hall. Guyton and Hall Textbook of Medical Physiology, 13th Edition , 2016, Elsevier

10.ECTS credits calculation

Form of activity Number of hours Number of ECTS credits

Direct hours with an academic teacher:

Lectures 65

Seminars 65

Practical classes 90

Student's independent work (examples of the form of work):

Student's preparation for a seminar 140

Student's preparation for a class 140

Preparation for obtaining credits

All 480 19

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11.Additional Information

Lectures winter semester:

2.10 at 9.30-11.30 at 8CBI, exceptionally on 8.10, 22.10, 19.11, 10.12 at 23 CBI

Summer semester

8.00-9.45 room 8 Library

Seminars:

Monday Group 3 and 4

Thursday Group 1 and 2

8.00-9.30 Classroom 7 low basement, Pawińskiego 3C

Classes

Group 1 Friday 17:00-20:00 dept. Classroom, Pawińskiego 3C

Group 2 Friday 14:00-17:00 dept. Classroom, Pawińskiego 3C

Group 3 Friday 11:00-14:00 dept. Classroom, Pawińskiego 3C

Group 4 Friday 08:00-11:00 dept. Classroom, Pawińskiego 3C

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32. Imprint

Faculty name: Faculty Of Medicine With The English Division

Education program (field of study, level

and educational profile, form of studies,

e.g., Public Health, 1st level studies,

practical profile, full time):

English Medicine Division, 1st level studies, practical profile, full time, compulsory

Academic year: 2019/20

Module/subject name: Immunology

Subject code (from the Pensum system): 45741

Educational units: Department of Clinical Immunology, Nowogrodzka 59 St

Head of the unit/s: Radosław Zagożdżon, MD PhD

Study year (the year during which the

respective subject is taught):

2

Study semester (the semester during

which the respective subject is taught):

second semester

Module/subject type (basic,

corresponding to the field of study,

optional):

basic

Teachers (names and surnames and

degrees of all academic teachers of

respective subjects):

Radosław Zagożdżon, MD PhD Anna Burdzińska, DVM PhD Monika Kniotek, MSc PhD Beata Kaleta, MPharm PhD Jan Borysowski, MD PhD Piotr Wierzbicki, MSc

Michał Zych, MSc Aleksander Roszczyk, MSc Katsieryna Marhelava, MSc

ERASMUS YES/NO (Is the subject

available for students under the

ERASMUS programme?):

YES

A person responsible for the syllabus (a

person to which all comments to the

syllabus should be reported)

Beata Kaleta

Number of ECTS credits: 3

33. Educational goals and aims

Immunology

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1. Familiarization with basic immunology in reference to elements of clinical immunology

3. Initial requirements

Basic knowledge from anatomy, physiology, cytophysiology

4. Learning outcomes corresponding to the subject

A list of course learning outcomes

Symbol of course learning

outcomes Description of course learning outcomes

The reference to

programme learning

outcomes (number)

S1 – S5, S7 - S12

Basic knowledge about development and mechanisms involved in innate and adaptive immunity (antibody-dependent and cell-dependent immunity)

C.W20

S6 The major histocompatibility complex C.W21

S13 – S16, S19 – S20 Hypersensitivity, autoimmune and allergic reactions, types of immunodeficiencies, basic knowledge about immunomodulation

C.W22

S17 The immune response to tumors C.W23

S18 Donor and recipient match genetic bases and transplantological immunology

C.W24

2. Forms of classes

Form Number of hours Number of groups

Lecture 0 0

Seminar 40 4

Practical classes 0 0

3. Subject topics and educational contents

S1- Seminar 1- Introduction to the immune system - C.W20 – Radosław Zagożdżon, MD PhD S2 – Seminar 2 – Cells and tissues of the immune system - C.W20 – Ania Burdzińdka, DVM PhD S3 – Seminar 3 – Circulation and migration of leukocytes - C.W20 - Anna Burdzińska, DVM PhD S4 – Seminar 4 – Innate immunity and natural killer cells - C.W20 – Monika Kniotek PhD S5 – Seminar 5 – Recognition of antigens by antibodies – C.W20 – Piotr Wierzbicki, MSc S6 – Seminar 6 – Presentation of antigens to T lymphocytes by major histocompatibility complex molecules C.W21 - Anna Burdzińska, DVM PhD S7 – Seminar 7 – Cytokines and signaling via immune receptors - C.W20 – Katsieyna Marhelava, MSc S8 – Seminar 8 - Development of lymphocytes and antigen receptor gene rearrangement- C.W20 – Radosław Zagożdżon, MD PhD S9 – Seminar 9 – Activation of T lymphocytes– C.W20 – Piotr Wierzbicki, MSc S10 – Seminar 10 – Differentiation and functions of effector T Cells - C.W20 - Anna Burdzińska, DVM PhD S11 – Seminar 11 – Activation of B lymphocytes and antibody production - C.W20 –Anna Burdzińska, DVM PhD S12 – Seminar 12 – Effector mechanisms of humoral immunity – C.W20 – Aleksander Roszczyk, MSc

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S13 – Seminar 13 – Specialized immunity at epithelial barriers and immune privileged tissues – C.W20 - Anna Burdzińska, DVM PhD S14 – Seminar 14 – Immunity to Microbes– C.W22 – Michał Zych, MSc S15 – Seminar 15 – Hypersensitivity disorders and allergy – C.W22 – Anna Burdzińska, DVM PhD S16 – Seminar 16 – Immunologic tolerance and autoimmunity – C.W22- Anna Burdzińska, DVM PhD S17 – Seminar 17 – Immunity to tumors – C.W23 –Radosław Zagożdżon, MD PhD S18 – Seminar 18 – Transplantation immunology – C.W24 – Jan Borysowski, MD PhD S19 – Seminar 19 – Acquired immunodeficiencies – C.W22 – Beata Kaleta , MPharm PhD S20 – Seminar 20 – Congenital immunodeficiencies – C.W22 –Radosław Zagożdżon , MD PhD

4. Methods of verification of learning outcomes

Learning

outcome

corresponding to

the subject

(symbol)

Forms of classes

(symbol)

Methods of verification of

a learning outcome Credit receiving criteria

C.W20, C.W21, C.W22, C.W23, C.W24

S (seminars) MCQ

26/50 positive answers and

maximum two inexcusable

absences on seminars

5. Evaluation criteria

Form of receiving credit in a subject:

grade criteria

2.0 (failed) 0-25 (out of 50) positive answers on MCQ and maximum

two inexcusable absences on seminars

3.0 (satisfactory) 26 – 33 (out of 50) positive answers on MCQ and maximum two inexcusable absences on seminars

3.5 (rather good) 34– 36 (out of 50) positive answers on MCQ and maximum two inexcusable absences on seminars

4.0 (good) 37 – 39 (out of 50) positive answers on MCQ and maximum two inexcusable absences on seminars

4.5 (more than good) 40 – 42 (out of 50) positive answers on MCQ and maximum two inexcusable absences on seminars

5.0 (very good) 43 – 50 (out of 50) positive answers on MCQ and

maximum two inexcusable absences on seminars

6. Literature

Obligatory literature: „Cellular and Molecular Immunology” (8th or 9th edition) (Cellular and Molecular Immunology, Abbas) Supplementary literature: „Riot,s Essential Immunology” (13th edition) by Peter J. Delves, Seamus J. Martin, Dennis R. Burton, Ivan M

Riott.

7. ECTS credits calculation

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Form of activity Number of hours Number of ECTS credits

Direct hours with an academic teacher:

Lectures - -

Seminars 40 1 and 1/3

Practical classes - -

Student's independent work (examples of the form of work):

Student's preparation for a seminar 20 2/3

Student's preparation for a class - -

Preparation for obtaining credits 30 1

Total 90 3

8. Additional Information

Three or more not excused absence must be made up with the teacher responsible for the topic (an oral

answer to two questions)

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34. Imprint

Faculty name: Faculty, English Division

Syllabus (field of study, level and educational profile, form of studies, e.g., Public Health, 1st level studies, practical profile, full time):

Hygiene and Epidemiology

Academic year: 2019/2020

Module/subject name: Hygiene and Epidemiology

Subject code (from the Pensum system): 45740

Educational units:

Zakład Epidemiologii i Biostatystyki

ul. Oczki 3, 02-007 Warszawa

tel 22 629 02 43

e-mail [email protected]

Head of the unit/s: Dr hab. n. med. Joanna Peradzyńska

Study year (the year during which the respective subject is taught):

II

Study semester (the semester during which the respective subject is taught):

III

Module/subject type (basic, corresponding to the field of study, optional):

basic

Teachers (names and surnames and degrees of all academic teachers of respective subjects):

dr hab. n. med. Joanna Peradzyńska

[email protected]

dr n med. Zbigniew Lewandowski

dr n. med. Daniel Rabczenko

dr n. hum. Cecylia Łabanowska

ERASMUS YES/NO (Is the subject available for students under the ERASMUS programme?):

Yes

A person responsible for the syllabus (a person to which all comments to the syllabus should be reported)

dr hab. n. med. Joanna Peradzyńska

Number of ECTS credits: 2,0

35. Educational goals and aims

Hygiene & Epidemiology

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1. Explaining of community health, its basic manifestations, presentation of health patterns and causes of health

problems in a population.

2. Presentation of population health demands and examinations of the most common health deficiencies population methods of investigation.

3. Learning how to determine the frequency of specific health problems, identify patterns in occurrences of the

problem, identify any potential causes and risk factors, evaluate the efficacy of preventative measures and

treatments

36. Initial requirements

1. Knowledge of microbiology, physiology and patophysiology basics obtained in school.

37. Learning outcomes corresponding to the subject

A list of learning outcomes

Symbol Description Number

(a number of a learning

outcome and its category: W-

knowledge, U-abilities,

K-competence)

W1 - knows health assessment methods of an

individual and of community, disease and

medical procedures classification

G.W1

W2

- knows ways of identification of risk factors,

advantages and disadvantages of different

epidemiological study methods and cause

relation measures

G.W2

W3 - knows epidemiology of communicable and

chronic diseases, methods of prevention on

the disease course

G.W3

W4 - knows the role of epidemic surveillance G.W9

W5

- knows the demographic structure of the

community and basing on it ia able to describe

population health problems

- is able to assess country epidemiological

condition of common diseases

G.W13

U1

- is able to assess diagnostic value of screening

tests; accuracy (sensitivity and specificity)

and repeatability

- is able to use epidemiological knowledge in

the infection outbreaks management

G.U1

U2

- is able to apply epidemiological knowledge in

the investigation of exogenous causes of the

main non communicable diseases on the

example of smoking and influence of other

factors

G.U2

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W1 - knows health assessment methods of an

individual and of community, disease and

medical procedures classification

G.W1

38. Forms of classes

Form Number of hours Number of groups Minimal number of

students in group

Lecture 0 0 -

Seminar 10 4

Practical classes 20 8 10 persons

39. Subject topics and educational contents

Classes and seminars

(W1-W5, U1, U2)

Definition basic concepts and aim.

Types of epidemiological studies, advantages and disadvantages.

Descriptive, analytic and experimental epidemiology.

Screening studies.

Community health measures in epidemiology.

Data sources of population health.

Epidemiological study interpretation.

Epidemiology of communicable diseases. Vaccination. Methods of community health monitoring.

Computer systems and data bases in healthcare.

Creation national and international data bases.

Aging as a medical and social problem.

Selected health problem global and student’s country epidemiology – presentation prepared by students.

Description of population health status basing on official statistical reports, disease registers and

designed studies. Health status in time and space evolution, health perspective of national and world

population.

Prophylaxis and clinical aspects in diagnosing and treatment early stage of diseases of chronic

diseases. Mass and selective screening tests of early stages of chronic, genetic and congenital

diseases.

Health conditions. Disease causation - recognizing methods. Risk factors. Basic types of

epidemiological phenomenons: epidemic, endemic, pandemic, epidemic process, epidemiological

surveillance. Communicable disease situation in the world. Basics of environmental epidemiology.

Clinical and epidemiological study methodology. Statistical methods use. The role of clinical

observations and epidemiological cross sectional study in disease causation hypothesis formulation.

Case control studies and cohort studies in disease etiology inquiring.

The role of clinical experiment (controlled clinical studies) in assessment of medical management

efficacy - basic of clinical epidemiology. Relative risk, odds ratio.

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Examples of disease fights in population based on communicable diseases and other health wellness

deviations of known external etiology.

Critical literature review.

40. Methods of verification of learning outcomes

Learning outcome

corresponding to the subject (symbol)

Forms of classes (symbol)

Methods of verification of a learning outcome Credit receiving criteria

W1-W5

U1-U2

Practical classes and

seminars

- classes attendance

- active discussion during

classes

MCQ final colloquium

- All classes and seminar attendance

- Selected health problem

epidemiology presentation.

MCQ test - correct answers at least

60%

41. Evaluation criteria

Form of receiving credit in a subject:

Grade Criteria

2,0 < 60% correct answers

3,0 60-75% correct answers

3,5 76-80% correct answers

4,0 81-86% correct answers

4,5 87-90% correct answers

5,0 Powyżej 90% correct answers

42. Literature

Obligatory literature:

1. Fiedman G.D. Primer of Epidemiology. McGraw-Hill, New York (available in the Institute)

2. R. Bonita, R. Beaglehole, T. Kjellström Basic Epidemiology 2nd Edition

3. Gerald van Belle, Lloyd D. Fisher, Patrick J. hearty, Thomas S. Lumley. Biostatistics: A methodology for

health sciences. 2nd Edition, August 2004.

4. L. Gordis. Epidemiology. Elsviere Saunders

5. www.who.org

Selected articles from medical literature.

Recommended literature

1. Jekel J.F, Elmore J.G, Katz D.L Epidemiology, biostatistics and preventive medicine. WB Saundres Comp,

Philadelphia 1996.

2. WHO Publications on selected topics (www.who.int)

European Center for Disease Control and Prevention Surveillance Reports (www.ecdc.europa.eu)

1. ECTS credits calculation

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Form of activity Form of activity Form of activity

Direct hours with an academic teacher:

Lecture 0

Seminar 0 0

Practical classes 30 1,0

Student's independent work (examples of the form of work):

Student's preparation for a seminar

Student's preparation for a class 15 0,5

Preparation for obtaining credits 15 0,5

Total 60 2,0

1. Additional Information

Classes are held at the Department of Epidemiology and Biostatistics, MUW, Oczki 3 str. Warsaw. Students are

obligated to participate actively. Presence on all classes is mandatory. In case of absence student should be present on

classes with another group (after agreement with teacher). Cloakroom is mandatory.

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1. Imprint

Faculty name: English Division

Syllabus (field of study, level and

educational profile, form of studies, e.g.,

Public Health, 1st level studies, practical

profile, full time):

English Division

6-year program

Full-time

Academic year: 2019/2020

Module/subject name: BASIC POLISH FOR MEDICINE

Subject code (from the Pensum system): 45742

Educational units:

Foreign Language Department

The Didactic Center, ul. Trojdena 2a., 02-109 Warsaw

[email protected], tel. 22 5720863

www.sjo.wum.edu.pl/

Head of the unit/s: Maciej Ganczar, PhD

Study year (the year during which the

respective subject is taught):

2nd

Study semester (the semester during

which the respective subject is taught):

Winter and summer semesters

Module/subject type (basic,

corresponding to the field of study,

optional):

Basic, compulsory

Teachers (names and surnames and

degrees of all academic teachers of

respective subjects):

Maciej Ganczar, PhD

Anna Maczkowska, MA

ERASMUS YES/NO (Is the subject

available for students under the

ERASMUS programme?):

A person responsible for the syllabus (a

person to which all comments to the

syllabus should be reported)

Anna Maczkowska, MA

[email protected]

Number of ECTS credits: 5

Syllabus BASIC POLISH FOR MEDICINE

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2. Educational goals and aims

1. The 2nd year Polish language course is designed to improve the students' command of the language and provide them with basic medical terminology and skills to communicate with an adult and paediatric patient at elementary level.

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3. Initial requirements

1. Successful completion of the 1st year Polish language course

4. Learning outcomes corresponding to the subject

A list of learning outcomes

Symbol Description

(a number of a learning outcome

and its category: W-knowledge,

U-abilities,

K-competence)

The successful student should be able to:

D.U.18

• take a patient's history at elementary Polish language level (personal history; chief

complaint (pain): location, radiation, quality, quantity, duration, frequency,

aggravating and relieving factors, associated symptoms; past history; family

history; drug history; social history; the review of systems)

• give simple instructions to an adult and paediatric patient during a physical

examination and explain the doctor's intentions

5. Forms of classes

Form Number of hours Number of groups

Lecture

Seminar

Practical classes 80 4

6. Subject topics and educational contents

Class duration: 2 hours 15 minutes (winter term) and 1 hour 45 minutes (summer term)

C1/Discussing the syllabus (the course content, learning outcomes and the methods of their verification; rules and

regulations; credit receiving criteria)

Parts of the human body • The verb boleć (singular&plural/present&past tense)

C2/Systems and organs • The cases of the noun and adjective in the singular&plural (revision) – forms and uses

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C3/The common cold and flu – a patient's description of the symptoms in the present/past tense • Time

expressions (revision) • Revision of the tenses (present&past) • Distinction between imperfective & perfective

verbs

C4/Problems with sleep • Questions: jak długo?, jak często?, ile razy?, od jak dawna?, O której godzinie? • The

modals móc and musieć (present&past tense)

C5/Diet: pieczywo (białe, ciemne), nabiał, mięso (tłuste, chude), wędlina, owoce, warzywa, napój (słodki,

nie/gazowany) • Advising a patient on a healthy diet: proszę jeść/nie jeść … • Containers and quantities: butelka,

szklanka, kubek, kieliszek, litr, deka, kilo, dużo, mało, więcej, mniej, trochę, ile, około (+ the genitive case)

C6/Allergies • Common allergens • Medication: lek/lekarstwo (na e.g. serce), tabletka, witamina, suplement diety,

lek przeciwbólowy / przeciwgorączkowy / przeciwzapalny / hormonalny, tabletki antykoncepcyjne • The verb brać/wziąć (singular/present&past tense)

C7/Physical activity • The verbs iść, chodzić, ćwiczyć, biegać (present&past tense)

C8&9/Instructions for the clinical examination of adults • Explaining the doctor's intentions to the patient • Future

simple tense of selected verbs (e.g. zbadać, osłuchać, zmierzyć, zrobić)

C10&11/Instructions for the clinical examination of children • Explaining the doctor's intentions to the patient •

The imperative mood

C12/Revision

C13/Progress test • Common diseases • The verbs chorować (na), leczyć się (na) (present&past tense), umrzeć (na)

(past tense)

C14/The medical interview: personal history (name, age, occupation, height, weight, marital/family status)

C15/The medical interview: social history – alcohol, smoking

C16/The medical interview: chief complaint • Common symptoms

C17, 18/The medical interview: past history – surgeries, injuries, hospital admissions, previous illnesses, birth

control, pregnancies / births, menstrual periods, allergies

C19/The medical interview: family history

C20, 21, 22/The medical interview: history of present illness (pain) – location, radiation, onset (timing, setting),

previous similar pain, duration, character, severity, exacerbating and relieving factors, associated symptoms

C23, 24, 25/The medical interview: systemic inquiry (basic questions)

C26/Revision

C27/Course written test • Speaking practice

C28, 29, 30/ Speaking practice – dialogues • Course oral test

7. Methods of verification of learning outcomes

Learning

outcome

corresponding

to the subject

(symbol)

Forms of

classes

(symbol)

Methods of verification

of

a learning outcome

Credit receiving criteria

D.U.18 C

Written test

Oral test

To successfully complete the II year Polish language course

and obtain credit, a student is required to:

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• attend all classes (min. 13 out of 15 in a semester)

A student who misses more than 2 classes per semester

without a valid excuse will not be allowed to take the course

tests and will not receive course credits.

Absences due to illness will be excused on presentation of a

valid medical note within one week of return to study. In the

case of two or more excused absences per semester the

student must make up the missed classes. If a student misses

a class, she/he must catch up on the missed material. It is the

student's responsibility to communicate with the class

teacher as soon as possible about any attendance issues.

• come to classes punctually

If a student arrives less than 15 minutes late three times per

semester, it will count as one absence. Arriving to class more

than 15 minutes late is counted as an absence.

• actively participate in each class

• complete all the assignments by the due date

• pass the progress test at the end of the winter semester and

the course written and oral tests (covering the coursework of

both the winter and summer semesters) at the end of the

summer semester

A student who fails the course tests can take two resits.

The final course grade a student receives is the average

(arithmetic mean) of the written and oral test grades (grades

of 2-5), or a grade of 3 for passing a resit. A minimum score of

60% must be obtained on each (written and oral) test to pass

the course.

A student who misses a scheduled test will receive a score of

0 unless she/he notifies the class teacher of the reason for

her/his failure to take the test within three days of the

scheduled test date and makes up the missed test if the

reason is justified at the date set by the class teacher.

A student who fails the second resit needs to repeat the

course.

Students who are 'independent users' of the Polish language

(Level B2 as described in the Common European Framework)

may be exempted from attending the second year Polish

language course provided they achieve the required score on

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the B2 level examination administered by the University's

Language Centre (Studium Języków Obcych) at the beginning

of the academic year. Students interested in taking the exam

should check with their class teacher for the exam date, time

and location at the first class meeting.

8. Evaluation criteria

Form of receiving credit in a subject:

grade criteria

2.0 (failed) Below 60%

3.0 (satisfactory) 60-69%

3.5 (rather good) 70-79%

4.0 (good) 80-85%

4.5 (more than good) 86-90%

5.0 (very good) 91-100%

9. Literature

Obligatory literature: Maria Janowska, Świetlana Sikorska “Proszę oddychać! Część III Warszawski

Uniwersytet Medyczny

Handouts prepared by the teachers

10. ECTS credits calculation

Form of activity Number of hours Number of ECTS credits

Direct hours with an academic teacher:

Lectures

Seminars

Practical classes 80 3

Student's independent work (examples of the form of work): doing home assignments

Student's preparation for a

seminar

Student's preparation for a

class 80 1

Preparation for obtaining

credits 80 1

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Other (please specify)

Total 240 5

11. Additional Information

(e.g., information on a scientific association operating within the unit, information on commuting to university, etc.)

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1. Course information

Name of the faculty: Faculty of Medicine

Mode of study:

Medicine

6-year program

Academic year: 2019/2020

Course name: Genetics

Course code:

Department responsible for curriculum:

Department of Medical Genetics

Center for Biostructure Research, First Faculty of Medicine

ul. Pawińskiego 3c, 02-106 Warszawa

phone: +48 22 572 06 95, fax: +48 22 572 06 96

http://www.genetyka.wum.edu.pl

Head of the Department: Rafał Płoski MD PhD

Year of study: 2 (second)

Semester of study: 4 (fourth)

Course level: mandatory

Teaching staff:

Rafał Płoski MD PhD

Joanna Kosińska PhD

Agnieszka Pollak PhD

Małgorzata Rydzanicz PhD

Piotr Gasperowicz MSc

Anna Walczak MSc

Victor Murcia-Pieńkowski MSc

Agnieszka Koppolu MSc

Erasmus YES/NO (is the course

available for students within Erasmus

program):

yes

Person responsible for curriculum

(person to whom comments can be made

concerning curriculum):

Krzysztof Szczałuba MD PhD

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Number of ECTS: 2

2. Course aims and objectives

The aim of the course is to present theoretical and laboratory basics of medical and clinical genetics. In the

course, the main focus is on teaching how to make use of the obtained knowledge in practice. Students will

also learn to interpret basic genetic analysis, understand principles of genetics counselling and will be

acquainted with basic laboratory and statistical methods used in the research in the field of human genetics.

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3. Prerequisites

Before the course a student:

1. knows the function of nucleotides in the cell; describes primary and secondary structure of DNA and RNA;

enlists interactions which stabilize these structures; describes chromatin structure (B.W13.);

2. knows functions of human genome, transcriptome and proteome as well as basic methods used in

studying them; describes processes of DNA replication, repair and recombination, transcription and

translation and DNA, RNA and protein degradation; knows basic concepts of gene expression regulation,

including epigenetic regulation (B.W14.);

3. knows processes such as cell cycle, proliferation, differentiation and aging of cells, apoptosis and necrosis

as well as their importance for functioning of the organism; explains the differences between mitosis and

meiosis (B.W22.);

4. knows the ways of communication between cells as well as between the cell and extracellular matrix and

pathways of transmitting signals in the cell and examples of disruption of these processes leading to cancer

and other diseases (B.W21);

5. passed a course in molecular biology.

4. Subject learning outcomes

List of learning outcomes

Learning outcomes

symbol Learning outcomes description

Learning

outcomes

reference code

W1 Student knows basic terms in the field of genetics. C.W1.

W2 Student describes phenomena of genes linkage and

interactions. C.W2.

W3 Student describes normal human karyotype. C.W3

W4 Student describes the structure of chromosomes and

molecular basis of mutagenesis. C.W4

W5

Student knows the principles of inheritance different number

of traits, inheritance of quantitative traits, independent

inheritance of traits and inheritance of extranuclear genetic

information.

C.W5.

W6 Student describes autosomal and heterosomal aberrations

which cause diseases. C.W6

W7

Student knows the basics of diagnostics of genetic and

chromosomal mutations responsible for inherited and

acquired diseases, including cancers.

C.W7, C.W9.

W8 Student knows factors which influence the primary and

secondary genetic balance of population. C.W8.

U1

Student analyzes genetic crosses and pedigrees of human

traits and diseases, and estimates the risk of giving birth to a

child with chromosomal aberrations.

C.U1.

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U2

Student calculates the risk of occurrence of a particular

disease in the offspring, based on familial predispositions

and the influence of environmental factors.

C.U5.

U3

Student uses databases, including on-line ones, and finds

information necessary for research (in the field of genetics).

U4

Student critically analyzes medical publications and draws

conclusions based on the literature available in the field of

genetics.

K1

Student is able to work in a group in order to solve a problem

from the field of genetics.

5. Teaching methods

Form Number of hours Number of groups Minimum number of

students in a group

Lecture 0 Not applicable

Seminar 8 Not applicable

Class 17 Not applicable

6. Course content

1. Basics of genetic medical history and pedigree analysis. Modes of inheritance in human. Genomic

imprinting. Drawing pedigrees based on clinical cases. Analysis of modes of inheritance – W1, W5, K1

2. Calculating genetic risk in multifactorial diseases. Applicability of RR and OR in medical genetics.

Calculating reoccurrence risk in monogenic diseases. Empirical estimation of disease likelihood in a family

using Bayes theory – W1, W8, U1, U2, K1

3. Usefulness of LR calculation in medical genetics. Calculating likelihood of pedigrees – U1

4. De novo mutations. Calculating genetic risk considering mutagenesis – W1, W7, W8, U1, U2

5. Genes identification and mapping. Linkage analysis – W1, W2, U1, U2, U3

6. Introduction to cytogenetic testing. Chromosomal basis of human diseases. Methods in molecular

cytogenetics. Analysis of cytogenetic results. Using online databases in CGH analysis – W1, W3, W4, W6,

U1, U2, U3, U4

7. Personalized medicine – whole-genome sequencing of DNA. Analysis of DNA sequencing results DNA –

W1, U2, U3, U4

7. Methods for evaluation learning outcomes

Learning

outcomes

symbol

Symbols of forms in

which the course is given

Methods for evaluation

learning outcomes Passing criteria

W1 – W8, U1-

U4 C, S Report from completed task

Solving correctly a given task

(drawing a pedigree based on

clinical description of a family;

interpreting a result of a genetic

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testing; calculating genetic risk;

defining a term; explaining a

biological process)

W1-W8, U1-U3 C, S Colloquium in a form of a

test

Answering correctly to more than

50% of questions

8. Evaluation criteria

Form of passing the course: passing without a grade

Grade Criteria

2,0 (ndst) Getting 50% of points or less

3,0 (dost) Getting more than 50% of points

3,5 (ddb)

4,0 (db)

4,5 (pdb)

5,0 (bdb)

9. Literature

Medical genetics

Jorde Lynn B., Carey John C., Bamshad Michael J.

Mosby Elsevier

Edition: 4th

10. ECTS estimation

Form of activity Number of hours Number of ECTS

Contact hours with teaching staff:

Lecture

Seminar

Class

Student's individual work:

Preparing for the class

Preparing for evaluation

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Other (which?)

Total

11. Additional information

Students are obliged to attend all seminars and classes. No absence is accepted during classes and

seminars. Each absence on classes and seminars would have to be covered with another group.

Change of groups is possible only as an exchange with a person from another group. Being late for

over 15 minutes counts as an absence.

Person responsible for students affairs: Krzysztof Szczaluba MD PhD

[email protected] , [email protected]

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43. Imprint

Faculty name: Faculty of Medicine, English Division

Education program:

6 year Medical Diploma Program, English Division.

Practical profile, full time.

Academic year: 2019/2020

Module/subject name: Medical First Aid

Subject code

Educational units:

1st Department of Anesthesiology and Intensive Care

Infant Jesus Teaching Hospital

W. Lindleya Street 4

02-005 Warsaw

0048 22 5021721

www.anestezjologia1.wum.edu.pl

2nd Department of Anesthesiology and Intensive Care

Public Central Teaching Clinical Hospital

Banacha Street 1a

02-097 Warsaw

0048 22 5992002

Department of Pediatric Anesthesiology and Intensive Care

Public Pediatric Teaching Hospital

63A, Żwirki I Wigury Street

0048 22 3179861

Head of the unit/s:

dr hab. n. med. Janusz Trzebicki

dr hab. n. med. Paweł Andruszkiewicz

FIRST AID WITH ELEMENTS OF NURSING

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dr hab. n. med. Izabela Pągowska-Klimek

Study year I and II

Study semester: II and IV

Module/subject type: Basic

Teachers:

dr hab. n. med. Janusz Trzebicki, Beata Błaszczyk MD PhD, Lidia

Jureczko MD PhD, Marcin Kołacz MD PhD, Rafał Kowalczyk MD PhD,

Karolina Dobrońska MD PhD, Grzegorz Górniewski MD PhD, Marek

Janiak MD, Marek Paśnicki MD, Paweł Zatorski MD PhD, Jan Pluta

MD, Ewa Puchalska-Kowalczyk MD, Piotr Andrzejak MD, Anna

Gruźlewska MD, Adam Kossut MD, Piotr Łącki MD, Adam Makowski

MD, Piotr Mieszczański MD, Anna Róziewska MD, Barbara Wrońska-

Podstawka MD, Maciej Barwijuk MD, Karolina Domaracka MD,

Agnieszka Cieniewicz MD, Magdalena Zawadzka MD, Anna Walczak

MD, Anna Makowska MD, Katarzyna Baścik MD, Nadzieja

Obuchowska MD, Dr hab. n. med. Paweł Andruszkiewicz, Łukasz

Wróblewski MD, Magdalena Mierzewska-Schmit MD PhD, A.

Baranowski MD, K. Jakubowska MD, J. Kalbowiak MD, W. Romaniuk

MD, M. Rykowski MD, P. Sawicki MD

ERASMUS YES/NO: Yes

A person responsible for the syllabus

Lekarz Marek Janiak

22 502 17 21, 22 502 16 85

[email protected]

Number of ECTS credits: 3

44. Educational goals and aims

1. Practical knowledge of cardiopulmonary resuscitation according to the latest guidelines.

2. Knowledge of assessment of vital signs in life threatening conditions.

3. Knowledge of recognition and treatment of life threatening conditions.

4. Acquisition of basic nursing skills in ambulatory and hospital care.

45. Initial requirements

Knowledge of the European Resuscitation Council 2015 Guidelines

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46. Learning outcomes corresponding to the subject

A list of course learning outcomes

Symbol of course learning

outcomes Description of course learning outcomes

The reference to

programme learning

outcomes (number)

W1 Knows main points of latest cardiopulmonary

resuscitation guidelines for neonates, children and adults F.W7.

W2

Identifies symptoms of the commonest overdoses such

as alcohol, narcotics and psychoactive substances,

heavy metals and select drugs

C.W44.

U1 Assesses general health state, level of consciousness of

a patient E.U7.

U2 Identifies life threatening conditions E.U14.

U3 Identifies alcohol intoxication and psychoactive substance

abuse E.U15.

U4

Performs basic medical procedures including:

a) Body temperature measurement, pulse count,

and blood pressure measurement

b) Monitoring of vital signs with the help of a

cardiomonitor and a pulse oximeter

c) Performs spirometry, oxygen therapy and

supports ventilation

d) Places an oropharyngeal airway device

e) Performs intravenous, intramuscular and

subcutaneous injection, intravenous cannulation,

venous blood taking and capillary blood taking

f) Takes a throat, nose and skin swab, performs a

pleural tap

g) Performs male and female urinary

cathetherisation, places a nasogastric tube,

performs a gastric lavage and enema

h) Obtains and assesses a standard 12 lead

electrocardiogram, performs cardioversion and

defibrillation

i) Performs simple strip tests and measures blood

glucose levels

E.U29.

U5 Initiates basic management in acute poisoning E.U33.

U6 Performs proper management of trauma (places a

bandage, immobilizes, manages and sutures wounds) E.U36.

U7 Acquires skill of intravenous cannulation F.U.5

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U8

Performs early limb immobilisation, chooses adequate

type of immobilisation in typical clinical scenarios and

controls the limb blood supply after applying an

immobilising bandage

F.U.8

U9 Manages external bleeding F.U.9

U10 Performs basic life support with external automated

defibrillation (AED) and first aid F.U.10

U11 Assesses level of consciousness according to used

international scales F.U21

K1 Knows own limitations and has skills for constant

continuing self education K.S4

47. Forms of classes

Form Number of hours Number of groups

Lecture - -

Seminar 9 1

Practical classes 36 1

48. Subject topics and educational contents

Seminar and practical classes in Departments: 10 hours (9 hours of seminars, 1 hour of practical classes)/

W1,W2,U1,U2,U3,U4,U5,U6,U7,U8,U9,U10,U11, K1

1MC1

1. S1 Introduction – safety of first responder and victim, infection risk. Cardiopulmonary Survival Chain. ABCD

approach. Contents of a First Aid Kit.

2. S2 The trauma victim transfer and treatment scheme: emergency system first and second responders, patient

transportation, diagnostic department, emergency department and intensive care unit.

1MC3 - Department of Pediatric Anesthesiology and Intensive Care

3. S3/C1 Rescue clinical scenarios, final test

Medical Simulation Center: (7 x 5 = 35 hours of practical classes)/W1,W2,U1,U2,U3,U4,U5,U6,U7,U8,U10,U11, K1

4. Basic Life Support (BLS) + Automated External Defibrillation (AED) in adults and children (PLEASE NOTE:

Students MUST come prepared for these practical classes with knowledge of 2015 European

Resuscitation Council BLS guidelines)

5. BLS + AED skills assessment. Trauma management and life-threatening conditions.

6. Basic nursing skills (subcutaneous injections, intramuscular injections, intravenous injections, setting up an

intravenous infusion, blood pressure measurement, heart rate assessment, vital signs monitoring, performing

an electrocardiogram (ECG).

49. Methods of verification of learning outcomes

Learning

outcome

corresponding to

the subject

(symbol)

Forms of classes

(symbol)

Methods of verification of

a learning outcome Credit receiving criteria

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W1, U1 W, S, C

Presence in all classes and

seminars. Practical skill

assessment.

Active part in all seminars and

classes. Individual cardiopulmonary

resuscitation (BLS) competence.

15 test questions.

50. Evaluation criteria

Form of receiving credit in a subject:

Grade criteria

2.0 (failed) No BLS skills and/or 0-7 points in final test

3.0 (satisfactory) Minimum BLS skills and/or 8-9 points in final test

3.5 (rather good) Adequate BLS skills and 10 points in final test

4.0 (good) Proper BLS skills and 11-12 points in final test

4.5 (more than good) Proper BLS skills and 13 points in final test

5.0 (very good) Proper and excellent BLS skills and 14-15 points in final

test

51. Literature

Obligatory literature:

2015 European Resuscitation Council guidelines

52. ECTS credits calculation

Form of activity Number of hours Number of ECTS credits

Direct hours with an academic teacher:

Lectures

Seminars 9 0,3

Practical classes 36 1,5

Student's independent work :

Student's preparation for a seminar 10 0,4

Student's preparation for a class 10 0,4

Preparation for obtaining credits 10 0,4

Other (please specify)

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53. Additional Information

The seminars start at 1st Department of Anesthesiology and Intensive Care, Lindleya Street 4 in the lecture room of the

Intensive Care Unit (closest to Lindleya Street entrance via Oczki Street into main building, first floor).

Simulations will take place at the Medical Simulation Centre in the Public Central Teaching Hospital, Banacha Street

(ground floor).

Seminars and practical classes also take place in Department of Pediatric Anesthesiology and Intensive Care

To limit overcrowding in the simulation center – students should not change their group without consent from the Head

of Unit Dr hab. n. med. Janusz Trzebicki or Dr Marek Janiak.

Any absence should be reported to Dr Marek Janiak or to the Head of Unit Dr hab. n. med. Janusz Trzebicki AND if

possible, the absence should be taken up with the next group.

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54. Imprint

Faculty name: Faculty of Medicine

Education program (field of study, level

and educational profile, form of studies,

e.g., Public Health, 1st level studies,

practical profile, full time):

Medicine

Academic year: 2019/2020

Module/subject name: Methodology

Subject code (from the Pensum system): 40968

Educational units: 1

Head of the unit/s: Prof. dr hab. n. med. Mariusz Z. Ratajczak

Study year (the year during which the

respective subject is taught):

II

Study semester (the semester during

which the respective subject is taught):

winter

Module/subject type (basic,

corresponding to the field of study,

optional):

basic

Teachers (names and surnames and

degrees of all academic teachers of

respective subjects):

Prof. dr hab. Mariusz Z. Ratajczak, dr hab. Magdalena Kucia,

dr Andrzej Ciechanowicz, dr Mateusz Adamiak, mgr Monika Cymer,

dr Anna Lenkiewicz,

ERASMUS YES/NO (Is the subject

available for students under the

ERASMUS programme?):

YES

A person responsible for the syllabus (a

person to which all comments to the

syllabus should be reported)

dr Andrzej Ciechanowicz

Number of ECTS credits: 1

55. Educational goals and aims

12. Define the types of scientific research.

Methodology

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13. Identify and describe the differences between types of scientific presentations.

14. List and define the main laboratory techniques and diagnostic tests used in scientific research.

15. Understand the mechanisms of surveys and be able to analyze them.

16. Use the appropriate form of presentation of results - graphically, descriptively and verbally.

17. Understand the ways of commercializing research results.

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56. Initial requirements

5. Knowledge of cell biology

57. Learning outcomes corresponding to the subject

A list of course learning outcomes

Symbol of course learning

outcomes Description of course learning outcomes

The reference to

programme learning

outcomes (number)

S1

The student got to know the types of scientific research.

The student understood the differences between

particular types of scientific research. The student defines

the scientific fields: regenerative medicine, experimental

hematology, genetics, epigenetics, immunotherapy, the

basics of drug research.

B.W10, B.W11, B.W12,

B.W13, B.W14, B.W23,

B.W28, B.W34, C.W1

S2

The student learned the principle of the main laboratory

techniques, such as: in vitro cell culture, RNA and DNA

isolation.

The student got acquainted with the principle of PCR and

Western Blotting methods, and also learned the principle

of inference based on the results obtained from these

techniques.

B.W4, B.W5, B.W6, B.W7,

B.W14, B.W34, C.W1,

C.W9

S3

The student learned the principle of dyeing and

cytometric analysis, as well as the principles of isolation

of cell populations from various biological materials using

magnetic beads.

B.W8, B.W34

S4

The student learned the main principles of choosing the

right statistical test for a particular research.

The student got to know various forms of data

presentation, such as oral presentations, multimedia

presentations or science posters.

The student learned the rules of creating scientific

publications and learned the legal consequences of

plagiarizing and falsifying results.

B.W31, B.W32, B.U12,

B.U14

S5

The student learned the principles of creating surveys

and conducting surveys.

The student got to know the phases of the drug

registration process.

B.W31, B.W34

S6

The student learned the rules of collecting clinical and

experimental data as well as their processing.

The student learned the principles of creating systematic

reviews and meta-analyzes.

B.W31, B.W34

S7

The student learned the main elements of patent law and

the protection of scientific data, which are the basis for

the commercialization of research results.

The student learned about the sources of funding for

scientific research.

B.U13

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S8

The student learned the main issues of ethics of scientific

research.

The student learned the basics of protecting sensitive

personal data.

The student got acquainted with legal requirements in

conducting animal tests and the basis for preparing

applications for appropriate ethical / bioethical

committees.

B.W34

C1 The student familiarized with the basic principles of

laboratory work.

B.W3, B.W10, B.W11,

B.U3, B.U5, B.U9

C2

The student acquired the practical skills of conducting cell

cultures in vitro, as well as isolation of genetic material -

RNA and DNA

B.W14, B.U9, C.W1, C.W9

C3

The student acquired practical skills to conduct the

analysis using flow cytometry as well as isolation of

various cell populations from the biological matrix.

B.W8, B.W34

C4 The student acquired practical skills in conducting PCR

analysis and Western Blotting. B.W11, B.W12, C.W1

C5 The student acquired practical skills in conducting

electrophoresis of agarose gels. B.W11, B.W12

C6 The student learned how to use selected medical online

databases. B.W31, B.U11

C7 The student got acquainted with the critical analysis of

scientific publications. B.W31, B.U14

C8 The student acquired practical skills to present the results

he obtained. B.U14

58. Forms of classes

Form Number of hours Number of groups

Lecture

Seminar 15

Practical classes 15

59. Subject topics and educational contents

Seminars:

1. Types of scientific research - regenerative medicine, experimental hematology, genetics / epigenetics,

immunotherapy, the basics of drug research.

2. Methodology in basic research (part 1) - laboratory techniques and diagnostic tests: in vitro cell cultures,

RNA and DNA isolation, PCR and Western Blotting.

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3. Methodology in basic research (part 2) - laboratory techniques and diagnostic tests: flow cytometry

methods, isolation of cell populations from biological material using magnetic beads.

4. Statistical analysis. Forms of data presentation – multimedia presentation, oral presentation, poster.

Principles of graphical presentation of results. Preparation of the publication. Legal consequences of

plagiarizing and falsifying results.

5. Survey research. Clinical trials - clinical trials, drug registration process.

6. Collection of clinical and experimental data and their processing. Creating systematic reviews and meta-

analyzes.

7. Commercialization of research results - patent law, protection of scientific data. Financing non-

commercial research - research grants.

8. Ethics in scientific research. Protection of sensitive personal data - GIODO RODO. Preparation of

applications to relevant ethics / bioethics committees. Legal requirements for conducting animal tests.

Practical class:

1. Basics of laboratory work.

2. Methodology in basic research (part 1) - laboratory techniques and diagnostic tests: in vitro cell cultures,

RNA and DNA isolation.

3. Methodology in basic research (part 2) - laboratory techniques and diagnostic tests: flow cytometry

methods, isolation of cell populations from biological material using magnetic beads.

4. Methodology in basic research (part 3) - laboratory techniques and diagnostic tests: PCR and Western

Blotting.

5. Methodology in basic research (part 4) - laboratory techniques and diagnostic tests: agarose gel

electrophoresis. Statistical analysis and analysis of results.

6. Medical databases - using the web of science, MEDLINE, PubMed, NIH genome project, etc.

7. Critical publication analysis - basic and clinical research. Journal club activities.

8. Presentation of student results.

60. Methods of verification of learning outcomes

Learning outcomes will be verified by the final results presentation by students, according to the rules students learned.

61. Literature

1. Literature will be provided during each seminar and practical classes.

62. ECTS credits calculation

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Form of activity Number of hours Number of ECTS credits

Direct hours with an academic teacher:

Lectures

Seminars 15 0,5

Practical classes 15 0,5

Student's independent work (examples of the form of work):

Student's preparation for a seminar

Student's preparation for a class

Preparation for obtaining credits

Other (please specify)

63. Additional Information

(e.g., information on a scientific association operating within the unit, information on commuting to university, etc.)

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64. Imprint

Faculty name: Faculty of Medicine

Education program (field of study, level

and educational profile, form of studies,

e.g., Public Health, 1st level studies,

practical profile, full time):

English Division, 1st level studies, practical profile, full time

Academic year: 2019/2020

Module/subject name: Introduction to Medical Communication

Subject code (from the Pensum system):

Educational units:

Department of Medical Psychology & Medical Communication

(practicals)

ul. Litewska 14/16

00-575 Warszawa

Tel. +48 22 116 92 11

Department of Medical Communication (e-learning)

ul. Żwirki i Wigury 81

02-091

Tel.22 5720578

Head of the unit/s: Professor Krzysztof Owczarek, MA, PhD

Study year (the year during which the

respective subject is taught):

II

Study semester (the semester during

which the respective subject is taught):

2nd semester

Module/subject type (basic,

corresponding to the field of study,

optional):

Basic

Teachers (names and surnames and

degrees of all academic teachers of

respective subjects):

Practicals: Magdalena Łazarewicz, MA, PhD; Joanna Chylińska, MA,

PhD; Marta Rzadkiewicz, MA, PhD; Urszula Ziętalewicz, MA and

Jakub Związek, MA

Introduction to Medical Communication

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E-learning: Agnieszka Oronowicz-Jaśkowiak, MD

ERASMUS YES/NO (Is the subject

available for students under the

ERASMUS programme?):

Yes

A person responsible for the syllabus (a

person to which all comments to the

syllabus should be reported)

Magdalena Łazarewicz, MA, PhD

[email protected]

Number of ECTS credits: 1

65. Educational goals and aims

18. During the course student acquires knowledge and skills on the basic psychological aspects of the medical interviewing, becomes familiar with the Calgary Cambridge model of communication and is able to apply its’ selected elements.

19. The student understands why good communication skills are important in medical practice and knows how to develop good rapport with patients and their families; is aware of different models of doctor-patient interactions and understands their consequences for medical outcomes.

20. The student gains basic knowledge and skills in verbal and nonverbal communication.

21. The student understands and applies principles of effective interpersonal communication in medical context: uses various techniques of active listening: open- and closed ended questions, facilitation, checking, clarification, summarising.

22. The student understands what empathy is and how to express it, is able to reflect and legitimate emotions, elicit patient’s concerns, ideas and expectations; know how to provide emotional support.

66. Initial requirements

None

67. Learning outcomes corresponding to the subject

A list of course learning outcomes

Symbol of course learning

outcomes Description of course learning outcomes

The reference to

programme learning

outcomes (number)

W1 Student understands the role of good verbal and

nonverbal communication in doctor-patient interaction, the meaning of trust in the interaction with patients

D.W04

W2 Communication as a tool used for establishing contact

and building relationship with a patient. First impression as a starting point in relation building process

D.W04

W3 The student can use different forms of questions

depending on the aim of communication D.W04

W4 The student is familiar with the rules of active listening D.W04

W5 The student is familiar with the methods improving

interpersonal communication and with the most frequent mistakes in communication.

D.W04

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W6 The student knows the rules of medical interview and in

medical team D.W04

W7 The student knows SPIKES protocol D.W04

W8 The student is familiar with motivational interviewing D.W12

U1

Student includes patient’s subjective needs and

expectations resulting from socio-cultural background in

the entire therapeutic process

D.U1

U2 Student builds the atmosphere of trust during the

treatment process D.U4

U3

Student conducts the consult with the patient with the use

of empathy and active listening; is able to discuss

patient’s life situation

D.U5

U4 Student applies basic psychological supportive

interventions D.U10

68. Forms of classes

Form Number of hours Number of groups

Lecture 20 1

Seminar - -

Practical classes 12 8

69. Subject topics and educational contents

C1 – Basic skills in medical communication (1)– the importance of communication for medical outcomes; basic rules

of building a good doctor-patient/family relationship: verbal and nonverbal aspects of communication; showing

respect and building rapport; eliciting patient’s perspective; active listening skills in gathering information;

questioning techniques - W1, U1-U2 – Magdalena Łazarewicz, MA, PHD, Joanna Chylińska MA, PhD, Jakub Związek,

MA, Urszula Ziętalewicz, MA

C2 - Basic skills in medical communication (2) – educating and explaining in medical practice; including patient’s

perspective in the treatment process, discussing treatment with patients, U3 – Magdalena Łazarewicz, MA, PHD,

Joanna Chylińska MA, PhD, Jakub Związek, MA, Urszula Ziętalewicz, MA

C3 - Empathy and support - responding to patient’s expectations and needs with empathy, eliciting and validating

emotional state of patients during treatment process, giving emotional support to patients, U4 – Magdalena

Łazarewicz, MA, PHD, Joanna Chylińska MA, PhD, Jakub Związek, MA, Urszula Ziętalewicz, MA

L - e-learning lectures, W1-W8 - Agnieszka Oronowicz-Jaśkowiak, MD

Functions of medical communication. Communication and patient satisfaction. The role of empathy in doctor-patient

relationship. Methods of communication. Communication barriers and errors. Medical interview. Breaking bad news.

Communication in medical team. Difficult conversations with patients. Motivational intervieving.

70. Methods of verification of learning outcomes

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Learning

outcome

corresponding to

the subject

(symbol)

Forms of classes

(symbol)

Methods of verification of

a learning outcome Credit receiving criteria

W1, U1-U4 C Active participation in all

exercises during classes

Minimal acceptable level of

performance

W1-W8 L

Completing the e-learning

course and submitting the

written exercise required in

the e-learning course

Minimal acceptable level of

performance

71. Evaluation criteria

Form of receiving credit in a subject: CREDIT

Grade criteria

2.0 (failed) --

3.0 (satisfactory) --

3.5 (rather good) --

4.0 (good) --

4.5 (more than good) --

5.0 (very good) --

72. Literature

Obligatory literature for practicals:

1. PDF materials provided by the teacher during the course.

Obligatory literature for lectures: provided e-learning materials.

Supplementary literature:

2. Silverman, J., Kurtz, S, Draper J (2008) Skills for Communicating with Patients. Radcliffe Publishing.

3. Desmond J, Copeland LR (2000) Communicating with Today’s Patients. Jossey-Bass. A Wiley Imprint.

4. Gordon T, Edwards WS (1997) Making the Patient Your Partner. Auburn House.

73. ECTS credits calculation

Form of activity Number of hours Number of ECTS credits

Direct hours with an academic teacher:

Lectures (e-learning) 20 0,25

Seminars - -

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Practical classes 12 0,25

Student's independent work (examples of the form of work):

Student's preparation for a seminar -

Student's preparation for a class 5 0,25

Preparation for obtaining credits - -

Other (please specify): preparation of e-learning

exercises 5 0,25

SUME 42 1

74. Additional Information

The class is intendent as practical and is based on experiential learning. The outcomes of that process are

strongly related to active participation in all in-class activities, therefore attendance is mandatory.

Students will be allowed to make up missed work in case of an excused absence. In such cases students

should notify the teacher as soon as possible to establish the way of covering the absence. Change of

subgroups is possible only after consulting the teacher in advance.

Students are expected to come to the class on time and participate actively. Being late for over 15

minutes counts as an absence. Recurring tardiness will result in additional work – an essay or short review

of literature (based on the decision of the teacher, depending on the missed material).

To provide good learning environment for everyone, students are requested to turn off any electronic

devices that might disturb the class.

To complete the course students are required to be present at all classes (with a possibility to come with

another group in case of absence – after teachers approval), participate actively in all exercises, complete

the e-learning course and submit the written exercise required in the e-learning course.

Contact information:

Department of Medical Psychology & Medical Communication (practicals)

ul. Litewska 14/16, 00-575 Warszawa

Tel. +48 22 116 92 11

Contact information to the course coordinator:

Magdalena Łazarewicz, MA, PhD

[email protected]

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Department of Medical Communication (e-learning)

ul. Żwirki i Wigury 81

02-091 Warszawa

Tel.22 5720578

[email protected]

The Department of Medical Psychology and Medical Communication runs the Psychological Students

Science Club “Psyche” (in English) (contact information: [email protected]).

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75. Imprint

Faculty name:

Education program (field of study, level

and educational profile, form of studies,

e.g., Public Health, 1st level studies,

practical profile, full time):

Faculty of Medicine, English Division, intramural, full-time, 6-

year Program

Academic year: 2019-20

Module/subject name: Medical Ethics with Elements of Philosophy

Subject code (from the Pensum system): 45736

Educational units:

Zakład Bioetyki i Humanistycznych Podstaw Medycyny

Chair of Bioethics and Medical Humanities

Żwirki i Wigury 63

02-091 Warszawa

tel.: (+48 22) 57 20 568

Head of the unit/s: Prof. dr hab. Tomasz Pasierski

Study year (the year during which the

respective subject is taught):

2

Study semester (the semester during

which the respective subject is taught):

2

Module/subject type (basic,

corresponding to the field of study,

optional):

basic

Teachers (names and surnames and

degrees of all academic teachers of

respective subjects):

Prof. dr hab. Paweł Łuków

ERASMUS YES/NO (Is the subject

available for students under the

ERASMUS programme?):

YES

MEDICAL ETHICS WITH ELEMENTS OF

PHILOSOPHY

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A person responsible for the syllabus (a

person to which all comments to the

syllabus should be reported)

Prof. dr hab. Paweł Łuków

Number of ECTS credits: 2

76. Educational goals and aims

23. Lectures: to acquaint students with the philosophical aspects of science and the theoretical-

philosophical foundations of medical ethics, together with the basic ethical concepts and standards

of physician’s ethic.

24. Seminars: to develop the skills which are necessary for analysis of medical-ethical problems,

appreciation of the ethical aspects of medical practice and decision making on the basis of the

knowledge acquired during lectures.

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77. Initial requirements

6. None

78. Learning outcomes corresponding to the subject

A list of course learning outcomes

Symbol of course learning

outcomes Description of course learning outcomes

The reference to

programme learning

outcomes (number)

W1 knows the philosophical foundations of evidence

based medicine D.W20.

W2 understands the physician’s social role D.W6.

W3

knows and understands the main concepts,

theories and ethical rules as the general framework

for appropriate interpretation and analysis of

moral-medical problems

D.W13.

W4 knows the principles of altruism and clinical

responsibility D.W14.

W5

knows the legal regulations relating to patient

rights, the basis of the profession of the physician,

and functioning of the medical self-government G.W6.

W6

knows the principles of medical confidentiality,

medical documentation, and penal, civil, and

professional liability of the physician G.W12.

U1

shows regard of the patient’s subjective needs in

the therapeutic process related to the social and

cultural conditions D.U1.

U2 creates the atmosphere of trust during the

therapeutic process D.U4.

U3 respects the ethical standards in professional

activities D.U12.

U4

can recognize the ethical dimensions of medical

decisions and differentiates between facts and

norms D.U13

U5

respects patient rights, including: protection of

personal data, privacy, respect for dignity, the right

to information, the right to confidentiality of

personal information, the right to informed

consent or refusal, the right to health services, the

D.U14.

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right to reporting of adverse effects of medicinal

products, the right to death with dignity

U6 explains to healthcare users their basic

entitlements G.U3.

79. Forms of classes

Form Number of hours Number of groups

Lecture 18 1

Seminar 12 4

Practical classes 0 0

80. Subject topics and educational contents

L1-Lecture 1: Philosophy and its main subdisciplines. Knowledge and types of science. W1

L2-Lecture 2: Inductive inference. Humanities. Basics of philosophy of science. Theories of truth. W1

L3-Lecture 3: Philosophical and methodological foundations of EBM. Ethics and medical professionalism

W1

L4-Lecture 4: Philosophical ethical theories. Ethical regulation in medicine. Justice in healthcare and

patient’s rights. W2, W3

L5-Lecture 5: Physician-patient relationship and informed consent. Patient’s decisional competency. W3,

W4, W5, W6

L6-Lecture 6: Physician’s professional autonomy. Medical paternalism. Truthfulness and confidentiality.

W4, W5, W6

S1-Seminar 1: Medical professionalism; W6, U3, U4, U6

S2-Seminar 2: Informed consent to medical services. Patient’s autonomy and decisional competency; W3,

W4, W5, W6, U1, U2, U3, U4, U5, U6

S3-Seminar 3: Physician’s professional autonomy. Medical confidentiality; W2, W4, W5, W6, U1, U2, U4,

U5, U6

S4-Seminar 4: Patient’s privacy. Ethics of the beginnings of life. W2, W3, W4, W5, W6, U1, U2, U3, U4, U5,

U6

S5-Seminar 5: Conflict of interest in healthcare; W2, W3, W4, U1, U3, U5

S6-Seminar 6: Ethical problems in paediatrics. End of life ethics. W2, W3, W4, W5, W6, U1, U2, U3, U4, U5,

U6

81. Methods of verification of learning outcomes

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Learning

outcome

corresponding to

the subject

(symbol)

Forms of classes

(symbol)

Methods of verification of

a learning outcome Credit receiving criteria

W1-W5 L1-L6 multiple choice test 60% correct answers

U1-U5 S1-S6

correct analysis of a

medical ethical case during

class presentation

acquisition of skill at acceptable

level

K1-K5 S1-S6

participation in class

discussions of assigned

reading materials

acquisition of skill at acceptable

level

Form of receiving credit in a subject:

grade criteria

2.0 (failed) below 60% of correct answers

3.0 (satisfactory) 60% of correct answers

3.5 (rather good) 65% of correct answers

4.0 (good) 70% of correct answers

4.5 (more than good) 80% of correct answers

5.0 (very good) 90% of correct answers

82. Literature

Obligatory literature:

5. R. Scruton, Modern Philosophy. An Introduction and Survey, Mandarin 1996, pages: 1-15, 16-20,

23-33, 34-45, 99-111, 183-186, 317-333.

6. T. L. Beauchamp, J. F. Childress, Principles of Biomedical Ethics, Oxford University Press 1994

(fourth edition), chap. 3-7.

Supplementary literature:

7. Scholarly journal articles selected for particular seminars. List of readings will be provided during first seminar.

83. ECTS credits calculation

Form of activity Number of hours Number of ECTS credits

Direct hours with an academic teacher:

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Lectures 18 0,96

Seminars 12 0,44

Practical classes 0 0

Student's independent work (examples of the form of work):

Student's preparation for a seminar 10 0,4

Preparation for obtaining credits 5 0,2

Other (please specify) 0 0

84. Additional Information