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UNIVERSITY OF NAIROBI, COLLEGE OF HEALTHSCIENCES AND KENYATTA NATIONAL HOSPITAL

Date: 19th - 21st June 2013Venue: Lecture Theatre III – College of Health Sciences, University of Nairobi, Kenyatta National Hospital Campus.

ISO 9001: 2008 CERTIFIED

SCIENTIFIC CONFERENCE2ND INTERNATIONAL

THEME: RESEARCH AND TRAINING FOR QUALITY HEALTHCARE

BOOK OF ABSTRACTSBOOK OF ABSTRACTS

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Quality Health Care

OUR MOTTO

To be a world class referral hospital inthe provision of innovative and

specialised healthcare

OUR VISION

To provide accessible specializedquality health care, facilitate medical

training, research, participate innational health planning and policy.

OUR MISSION

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• QUALITY POLICY STATEMENT – UNIVERSITY OF NAIROBIThe University of Nairobi is committed to quality as the guiding principle in its decision making and leadership in the provision of university education and the related services to its customers.To realize this, the University management shall regularly monitor and review its performance for continual improvement and suitability by implementing an effective quality management system based on ISO 9001 standard.

• QUALITY POLICY STATEMENT - KNHThe Management of Kenyatta National Hospital and the entire staff are committed to continued provision of accessible specialised quality healthcare, facilitate Medical Training, and Research.The implementation of this quality policy and objectives shall be periodically reviewed for suitability to continually conform to the requirements of the;

MEMBERS OF THE 2ND INTERNATIONAL SCIENTIFIC CONFERENCE 2013, STEERING COMMITTEEProf. Anastasia N. Guantai (Chairperson)Prof. S. W. O. OgendoProf. Ezekiel WafulaProf. Nilesh PatelDr. Mirie WaithiraDr. John KinuthiaDr. Beatrice AmuguneDr. Nelson MatuDr. George OsanjoDr. Sarah MuniuMs. Lucy BitokMr. Josephat KiongMr. Joseph WaigwiMr. Kennedy GitauMs. Winnie KasinaMr. Harrison MwendaMs. Clare KagwiriaMr. Stephen Mulwa

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MESSAGE FROM THE CONFERENCE CHAIR: On behalf of the International Scientific Conference (ISC) organizing committee, I welcome you all of you to the 2nd International Scientific Conference 2013. This event has been organized by Kenyatta National Hospital and College of Health Sciences, University of Nairobi.

The host institutions are leading providers of healthcare services, training and health research. You recall that in June 2011 we held our first inaugural scientific conference whose theme was “Towards optimum healthcare”. The focus for this second international scientific conference is “Research and Training for Quality Healthcare”. Research embodies the discovery and/or the development of new knowledge or products, acquisition of new tools /skills. This conference will provide a unique opportunity to both national and international community of health care providers to interact and examine all aspects that relate to the theme of the conference. It will also allow participants to capture and take stock of a broad spectrum of issues in Health research, practice, product discovery, innovation and development. These issues will further be interrogated by the participants, observations made and relevant recommendations drawn to guide future health research, practice and policy.

It has been a privilege working with a dedicated team of scientists and administrators in organizing this event. This conference has received significant support from the University of Nairobi and Kenyatta National hospital administration and particularly Prof. Isaac Kibwage and Mr. Richard Lesiyampe who have provided financial and logistical support.

Let me also take this opportunity to thank Prof. Jacob Kaimenyi, Cabinet secretary, Ministry of Education, Science and Technology for accepting to grace us with his presence as the guest of honour during the opening ceremony. My sincere thanks also go to the cabinet secretaries, Ministry of Health and Ministry of Devolution and Planning respectively for their support in the delivery of the plenary lectures in day two and three of the conference.

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A critical look at the plenary lecture topics will confirm that these are topics of national interest at this stage of political history in Kenya. This rich mix of professional knowledge and experience clearly makes this conference unique and a “must attend”. Once again welcome all to the FORUM.

Prof. Anastasia N. Guantai

Chairperson, ISC Organizing Committee 2nd International Scientific ConferenceCollege of Health Sciences (UoN) and Kenyatta National Hospital

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Scientific Programme for Wednesday 19th June 2013DAY ONE

Details of the Activity

Registration

Discussion of Presentations

Morning Tea Break

Prof. Isaac O. Kibwage Principal, College of HealthMr. Richard L. Lesiyampe , CEO, Kenyatta National Hospital

Welcome of Delegates:

Conference Overview:

Lecture Theatre 3 Surgery Boardroom

8:00 to 9:00 am

9: 30 to 9: 40 am

9: 50 to 10: 00 am

9: 50 to 10: 00 am

10:00 to 10:10 am

10:10 to 10:30 am

10:30 to 11:00 am

Prof. Anastasia N. Guantai, Chair, Steering Committee conference

SESSION A Chair: Prof. E. AmayoCo-Chair: Dr. J. OngechRapporteurs: Dr. M. Obimbo Dr. F. Okalebo

SESSION B Chair: Prof. E. M. ObimboCo-Chair: Dr. B. GithaeRapporteurs: Dr. J. Maina, Dr. E. Karari

Abstract 54 - Minnie KiboreAn evaluation of a pilot decentralized trainingrotation for medical students at the Universityof Nairobi

Abstract 23 - Mitheko AgnesDietary, Socio-economic and Demographicfactors influencing serum zinc levels ofpregnant women at Naivasha level 4 hospitalNakuru county, Kenya

Abstract 3 - Emma KhaembaThe Survival of Patients with Cancer of the Cervixin Nairobi, Kenya

Abstract 8 - Rutare SPrevalance of MRSA among paediatricpatients in ICU KNH

Abstract 16 - Faiza NassirUrological complications and Impact on quality oflife among patients with Cervical Cancer atKenyatta National Hospital

Abstract 24 - Jeffrey EdwardsThe demographic and clinical characteristicsof children diagnosed with rickets who livewithin the informal settlement of Kibera,Nairobi,Kenya

Abstract 57 - James KiariePartnership for Innovative Medical Educationin Kenya (PRIME-K)

Abstract 26 - Kamau EmilyEffectiveness of PMTCT at NaivashaHospital: Outcomes of HIV exposed infants:

Master of Ceremony: Dr. Walter Odhiambo Chief Rapporteur: Dr. George Osanjo Deputy Rapporteur: Dr. John Kinuthia

UNIVERSITY OF NAIROBI, COLLEGE OF HEALTHSCIENCES AND KENYATTA NATIONAL HOSPITAL

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Discussion of the First Plenary Session

Poster SessionLunch Break and Poster Session

Responder: Prof. M. Chindia , Dr. Irene Inwani

12:00 to 12:20 pm

12:20 to 13:00

10:00 to 10:10 am

12:20 to 14:00 pm

SESSION C Chair: Dr. D. Ongore Co-Chair: Dr. W. SigilaiRapporteurs: Dr. P. Muiruri Dr. B. Omunga

SESSION DChair: Prof. Mary WagaiyuCo-Chair: Prof. E. NguuRapporteurs: Dr. Nyamori Dr. E. Kihara

First Plenary Session by: Professor Jacob KaimenyiCabinet Secretary, Ministry of Education, Science & Technology

and official opening of the Conference

Topic: The National Research Agenda Venue: Lecture theatre 3Chair: Prof. A. Guantai Rapporteur: Dr. S. Ngare

14:00 to 15:30 pm

15:30 to 17:00 pm

Abstract 15 - Muluemebet A.Magnitude of early sexual debut and its correlatesamong college youth of Gambella town,South western Ethiopia

Abstract 32 - Wanjala FredinardFree Fibula Flaps under Loupe magnification;A viable option for reconstruction of bonydefects in a resource constrained environment

Abstract 17 - Muturi NellyFactors associated with risky sexual behaviorpractices among HIV negative partners in HIVdiscordant relationships in Nairobi, Kenya

Abstract 37 - Kitunguu P. Pituitary surgery at the Kenyatta NationalHospital

Abstract 22 - Obiero JaelSafety and contraceptive studies of Unipron

Abstract 56 - Njiri FStrengths and Challenges of DecentralizedHealth Facilities as Medical Training andResearch Sites in Kenya

Abstract 29 - Bitok LucySelf-Reported Use of Internet by Cervical CancerClients in Two National Referral Hospitals in Kenya

Abstract 76 - Onesmus GachunoElimination of Vertical transmission ofHIV – The option B plus experience atUniversity Teaching hospital

Discussion on Presentations

Afternoon Tea Break and Poster Session

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Scientific Programme for Thursday 20th June 2013

Details of the ActivityTime

Discussion of Presentations

Discussion of Presentations

Morning Tea Break

Lecture Theatre 3 Surgery Boardroom

8:30 to 9:00 am

9:00 to 9:10 am

9:10 to 9:20 am

9:20 to 9:30 am

SESSION EChair: Prof. S. M. BhattCo-Chair: Prof. F. E. OnyangoRapporteurs: Dr A. Bashir Dr. A. Laving

SESSION FChair: Prof. N. PatelCo-Chair: Prof. G. N. ThoithiRapporteurs: Dr. C. Githinji Dr. E. Muge

SESSION GChair: Prof. W. Mwanda Co-Chair: Dr. D. Wamalwa

SESSION HChair: Prof. P. Opinya Co-Chair: Dr. H. Kioko

Rapporteurs: Dr. N. Kariuki Dr. J. Oyugi

Rapporteurs: Dr. O. Gachuno Dr. G. Mwango

Abstract 31 - Dr: Dan AlaroPrevalence and Short-term outcomes of acute kidneyinjury in term neonates with moderate to severe PerinatalAsphyxia at the Kenyatta National Hospital newborn unit

Abstract 7 - Munyikombo WEffect of Fresh Aqueous Garlic Extract (AlliumSativum L:) on Erythropoiesis in Adult MaleRabbits:A Study on Peripheral Blood Analysis:

Abstract 53 - Rachel MusokeClinical course and outcome of HIV positive childrenresident at a children's home in Nairobi:A 15 year review (1995-2010)

Abstract 11 - Milugo Trizah KoyiPhytochemical composition, antioxidant andantitumor effects of extract from Drum stick(Moringa Oleifera) and Quinine tree(Rauvolfia caffra)

Abstract 58 - Wangia S:Factors influencing adherence to Antiretroviral therapyamong HIV infected and HIV exposed children atNaivasha District hospital

Abstract 14 - SineI KiprutoAn In vitro study on the Oxytocic action ofAdenia Globosa Engl

Abstract 63 - Catherine MutindaAdherence to the National Guidelines for Managementof children with pneumonia at GPGH

Abstract 69 Jamleck KarumbiTopical Umbilical Cord Care for Prevention ofInfection and Neonatal Mortality

Abstract 55 - Warfa OEvaluating the Implementation of Ministry of HealthGuidelines in the Management of SevereMalnutrition at the Garissa Provincial General Hospital,Garissa, Kenya

Abstract 5 - Jesca WambaniAssessment of Quality Management in CTMachines in Kenya

Abstract 61 - Mwaura J: NPrevalence of STIs among MARPs enrolledin Thika CCC

Abstract 41 - Nimrod MwangombeNeuroepidemiology of Head Injuries in Kenya

Abstract 20 B - Walter Odhiambo Pilot study on the use of Internet Social Network siteas a vehicle for Multicenter injury Research:

Abstract 45 - Mary KikuviAn Audit on Pain management at emergencydepartment KNH

15:30 to 17:00 pm

15:30 to 17:00 pm

10:40 to 11:10 am

11:10 to 11:40 am

9:30 to 10:00 am

DAY TWO

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Discussion of Presentations

Afternoon Tea Break and Poster Session

11:40 to 12:20 pm

12:20 to 12:40 pm

12:40 to 13:00 pm12:40 to 14:00 pm

14:00 to 14:10 pm

14:10 to 14:20 pm

SESSION IChair: Prof. J. M. Machoki Co-Chair: Prof. Zembi Ngumi Rapporteurs: Dr. S. Mutiso Dr. E. Guantai

SESSION JChair: Prof. B. K. Bhatt Co-Chair: Prof. D. Ilako Rapporteurs: Dr. E. Nyenze Dr. Irene Weru

Abstract 10 - Anthony WainainaPrevalence and Determinantsof Needle Stick Injuries atKenyatta National Hospital,Nairobi Kenya

Abstract 68 - Ezekiel MechaTransforming Growth Factor betas enhance Secretion ofMatrix Metalloproteinases andPlasminogen Activator Inhibitor-1 of HumanEndometrial and EndometrioticCells:

Abstract 28 - Gloria OmosaPre-screening and �banking�participants for clinical research� Experience from Kenya AIDSVaccine Initiative (KAVI)

Abstract 6 - Mike KidaliAssessment of RaditionExposure during InterventionalProcedures in Kenya

Abstract 47 - Kinge WaithaikaGlomerular filtration rateassessment using Creatininerelated parameters for healthyadult Kenyan population

Abstract 74 - David WataDeterminants of BreastCancer Tamoxifen TherapyOutcomes at KenyattaNational Hospital

Abstract 84 - F: NdiawoUse of mechanical CPR could improveresuscitation outcomes in KNH:

Abstract 51 - Beatrice AmuguneAn audit of hospital radio-pharmacypractice at Kenyatta National HospitalNuclear medicine unit

Abstract 67 - Mary AtienoPatterns of Antibiotic Use and Dose Adjustmentin Patients with Chronic Kidney Disease atKenyatta National Hospital, Kenya

Abstract 65 - John FondoClinical outcomes of children aged 6 to9 months with severe acute malnutritionadmitted to Mbagathi District Hospital

Abstract 71 Beatrice OgolaThe Safety and Tolerability of Low DoseStavudine Versus Zidovudine in Patientsat Kenyatta National Hospital

Abstract 66 - Everlyn NgangaPrevalence of early onset sepsis in termnewborn deemed at risk in the postnatal wards of Kenyatta National Hospital

14:30 to 14:40 pm

14:40 to 14:50 pm

14:50 to 15:00 pm

15:00 to 15:40 pm

15:40 to 17:00 pm

14:20 to 14:30 pm

Topic: Provision of Quality Health Care in a Devolved System

Chair: Prof. C. A.Omwandho Rapporteur: Dr. F. A. Okalebo

Discussion of the Second Plenary Session

Poster SessionLunch Break and Poster Session

Second plenary session by: Ms Anne WaiguruCabinet Secretary, Ministry of Devolution and Planning

Venue - Lecture theatre 3

Responder: Prof. E. Ogola Dr. Owen Ogony

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Scientific Programme for Friday 21st June 2013Details of the Activity

Time Lecture Theatre 3 Surgery Boardroom

8:30 to 8:40 am

8:40 to 8:50 am

8:50 to 9:00 am

SESSION KChair: Prof. P. Kioy Co-Chair: Prof. C. F. Otieno Rapporteurs: Dr. P. Njogu, Dr. J. Rajab

SESSION LChair: Prof. Muia Ndavi Co-Chair: Prof. H. Saidi Rapporteurs: Dr. K. Kabia, Dr. D. Bukusi

SESSION MChair: Dr. G. Omoni Co-Chair: Prof: H.Oburra Rapporteurs: Dr. W. Otsianyi, Dr. K. Ondede

SESSION NChair: Prof. S. OgendoCo-Chair: Dr. C. Gontier Rapporteurs: Dr. J. Kuria, Mrs. M. Kinoti

Abstract 75 - Margaret OlukaDetermination of Nevirapine plasma levelsby high performance liquid chromatographicmethod

Abstract 78 - Samuel KimaniTreatment compliance among patientswith hypertension at Kenyatta NationalHospital (KNH)

Abstract 27 - Birechi JenniferChild Marriage;A Cultural Health Phenomenon

Abstract 85 - James KiarieReproductive health decisions and HIVinfection risks among heterosexualcouples in stable relationships

Abstract 62 - Zahida QureshiMaternal deaths and Maternal Near Miss casesin 20 selected facilities in Kenya

Abstract 86 - Pamela AkinyiHIV risk and pregnancy intention

Abstract 87 - Nelly Mugo Couples most at risk of HIV

Abstract 82 - Osoti AlfredUptake of combination of HIV preventioninterventions among participants in acommunity enrolled cohort

Abstract 39 - Kitunguu P. (A)Management and outcomes of ExtraduralHaematomas at Kenyatta National Hospital

Abstract 83 - Kinuthia JohnPregnancy rates after HIV testing amongcouples in stable partnerships inWestern Kenya

Abstract 33 - Fredinard Wanjala Flaps in reconstructing leg defects;Our experience at Kenyatta National Hospital

Abstract 13 - Gikore PAn Evaluation of Acute Pain Management onPost Operative Patients in Surgical, Obstetricsand Private Wing in Kenyatta National Hospital

Abstract 88 - Wamalwa D.Strengthening Maternal Neonatal and child health plementation science research in non-tertiaryhealth facilities in Kenya

9:10 to 9:20 am

10:30 to 10:40 am

10:40 to 10:50 am

9:20 to 9:30 am

Discussion on PresentationsMorning Tea Break10:00 to 10:30 am

9:30 to 10:00 am

Abstract 98 - Andrew NyandigisiMalaria case-management following change ofpolicy to confirmed diagnosis and targeted ACTtreatment in Kenya

Abstract 81 - Kinuthia JohnDeveloping Maternal new born and child healthcapacity in implementation science, leadershipand management through training

Abstract 38 - Kitunguu P Predictors of Functional Recovery in AfricanPatients with Traumatic Intracranial Hematomas

10:50 to 11:00 am

Abstract 42 - Nimrod Mwangombe Neuroepidemiology of Brain Tumours Kenya

Abstract 79 - Godfrey MutumaThe value of autopsy - overview

11:00 to 11:10 am

Abstract 43 - Nimrod mwangombe Neuroepidemiology of Spina Bifida Cysticain Kenya:

Abstract 72 - Sofia MwenyisheeMissed diagnosis of malnutrition in childrenaged 6-59 months attending care at Mbagathidistrict hospital

11:10 to 11:20 am

Discussions on Presentations11:20 to 11:40 pm

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Discussion of the Third Plenary Session

Poster SessionLunch Break and Poster Session

Responder: Prof Joseph Oliech, Dr. J. Ongech

11:40 to 12:20 pm

12:20 to 12:40 pm

12:40 to 13:00

12:40 to 14:00 pm

12:40 to 14:00 pm

15:00 to 16:30 pm

Topic: Public-Private Partnership in engaging Research for Quality Health Care

Fourth Plenary session - Prof. Omu Anzala

Closing Ceremony and Awards Presentations in lecture Theatre 3

Venue: Lecture theatre 3Chair: Dr. Simeon Monda Rapporteur: Dr. W. Mirie, Dr. L. Bitok

Third Plenary Session by:Mr. James Wainaina Macharia

Cabinet Secretary, Ministry of Health

Topic : HIV Vaccine development for HIV and discussionsChair: Prof. Jaoko Rapporteur: Dr. Mutua (KAVI)

Dr. B. Farah (KAVI)

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Attitudes and Perceptions of Medical Trainees towardsComplementary and Alternative Medicine Use

Serial No. Presenter Abstract Title

Poster PresentationsAbstractNo.

Henry Nyongesa1. 1

Preliminary results on the use of cytokines and chemokines todetect TB infection in HIV individuals

Machuki Zipporah 2. 19

“The Kigali Boy with a Massive Tongue but No Respiratory distress”A Case Report on a massive Cervico-lingual Cystic Hygroma.

Walter Odhiambo 3. 20 A

accreditation : The Kitale District Hospital experienceJumba Godfrey 4. 21Who owns the Maxillary Sinus? Incidental findings inCone-Beam CT scans of the Maxillary Sinus

Kihara Eunice 5. 25

Questionnaire Survey on the Occurrence of Risk factors forToxoplasma gondii infection amongst Farmers in Thika District, Kenya

Edwin Ogendi6. 34

Hospital evacuation plan: assessment of staff preparednessin event of internal disaster at Kenyatta National Hospital

Ali Akida W.7. 36

Pamoja Project: Using Cotrimoxazole Preventive Therapy tostrengthen referral/linkage to care & treatment amongmost-at-risk populations (MARPs) in Kajiado County, Kenya.

Anne Mungai8. 40

The role of Intracranial Pressure (ICP) Monitoring in theManagement of Severe Traumatic Brain Injuries (TBI) in Kenya.

Nimrod Mwangombe D9. 44

Hybrids of (2r,3s)-n-benzoyl-3-phenylisoserine andantimalarialpharmacophores: design, synthesis and biological evaluation

Peter Njogu10. 48

Prevalence of Anaemia among pregnant women attendingantenatal clinic at Mbagathi District Hospital

Nduhiu githinji11. 49

Epidemiology of toxoplasmosis and identification of riskfactors among slaughterhouse workers across Kiambu county

Ichagichu James12. 50

Data driven decision making in Kenya's health care sectorJosephine Karuri13. 52Impact of HIV and AIDs comprehensive prevention andsupport programme on HIV transmission among MARPSCentral and Eastern Provinces

Kageni Nderitu14. 59

Use of Low Cost Mobile Telephony and Online connectivity forCost-effective community health strategy program in RariedaDistrict: success

Ogude Gideon15. 73

Evidence from literature for Hydroxyurea in prevention of sickle celldisease complications in children title rewritten

Mercy Maluka16. 79

Prevalence of low birth weight babies and the associated maternalrisk factors at Naivasha District Hospital

Angelina Ithondeka17. 80

Prevalence of musculoskeletal pain in Nairobi: results of a phase1, Stage 1 COPCORD study

Paul Etau Ekwom18. 89

Peter J. Changwa19. 90Pap smear cytological findings in women with abnormal visualinspection test results referred to Kenyatta National Hhospital

Immaculate Mutisya20. 91Fighting HIV and Acute Leukaemia Five Years on

Wagechi Mbuthia21. 92Fertility desires among hiv infected adults at Naivasha DistrictHospital

Edwin Walong22. 93Case report: an unusual vulval lesion resembling granulomainguinale

A four month female infant presenting with primaryimmunodeficiency diagnosed at autopsy: a case report

Edwin Walong23. 94