E U R O P E A N

C U R R I C U L U M V I T A E

F O R M A T

PERSONAL INFORMATION

Name

Address

Telephone

Fax

E-mail

Nationality

Date of birth

WORK EXPERIENCE

• Dates (1989-2011)

Page 1 • Curriculum vitae of [ SURNAME, othernames ]

RUVOLO GIOVANNI

29, Via L. Bissolati, 93100 Caltanissetta, Italy

+39.0934.553970

+39.091.323412

ruvologi@hotmail.com

Italian

08-05-1966

Mobile: +39.338.5941344

2012: WlNNER O F T H E INTERNATIONAL PRIZE " G R A N T F O R FERTILITY INNOVATION (GFI) 2012"

2012 Professor at the Master in Reproductive Biotechnologies applied to ART at The University of Basilicata, Italy

• 2010 Member of the national committee of the SIFES MR • 2010 -2014 Scientific director and clinical embryologist at Centro di Biologia della

Riproduzione, Via V. Villareale, 54 - 90141, Palermo, Italy • 2010-1999: Contract Professor at the Endocrinology Department, Catania

University, Italy • 2014 - 2000: Scientific Coordinator of the "Permanent Stages of Human

Reproductive Phisiopathology" organized by Centro di Biologia della Riproduzione and by Fondazione per gli Studi sulla Riproduzione Umana (President Prof. Ettore Cittadini)

• 2010 - 1999: Teaching at the "Permanent Stages of Human Reproductive Phisiopathology" organized by Centro di Biologia della Riproduzione and by Fondazione per gli Studi sulla Riproduzione Umana (President Prof. Ettore Cittadini)

• 2007: Coordinator of the Master "Biotechnology and reproduction, at the Obstetric and Gynecology Department, University of Palermo

• 2006: Contract Professor in the Obstetric and ginecology School, Palermo University, Italy

• 2005: Professional Consultant at "Azienda Ospedaliera" to design and For more information go to www.cedefop.eu.int/transparency/ europa.eu.int/comm/education/index_en.html eurescv-search.com/

project an IVF laboratory and service 2004: Research collaboration with the Departiment of Developmental Biology, University of Palermo, for research on Apoptosis in human oocytes and in ovarian tissue in oncological female patients after freezing-thawing procedures. 2000 - 1992: Engagement as embriologist in the IVF Lab of "Centro di Medicina della Riproduzione", Palermo, Italy. Clinical and Scientific Director: Prof. Ettore Cittadini 1990: Fellowship in the IVF Lab of the "Istituto Materno Infantile" University of Palermo, Italy 1989: Voluntary in the IVF Lab of the "Istituto Materno Infantile" University of Palermo, Italy

E D U C A T I O N A N D TRAIN ING

2003: Degree in Biotecnology, in the University of Palermo (110/110 with mention). 1988: Degree in Biology in the University of Palermo,ltaly (110/110 with mention);

2012: Winner of the prize Grant for Fertility Innovation (GFI) 2012 2008: Eshre senior embryologist certificate June-September 2006: Fellowship at McGill University (Prof. Tan, Prof. Ri Chi Chang) in Montreal for a research project on human and mouse oocyte in vitro maturation and vitrification 2003: Founder of Italian Scientific Review "2 PN" Development in Reproductive Biology; 2000: Job Experience in DEXEUS University, Barcellona, Spain, in the Genetic and IVF Lab (Dr. Ana Veiga), for a collaboration in Pre implantation Genetic Diagnosys (PGD) (1 week); 1997: Founder ofSIERR, Italian Scientific Society of Clinical Embriologist; 1995: Job experience in Bruxelles, Belgium, for the acquisition of the practice of round spermatids selection for ICSI programme in IVF Lab of Prof. R. Schoysmann, (1 month); 1993: Partecipation in Bruxelles, Belgium, at the ICSI Stage, in AZ-VUB University ( Prof. Van Steirteghem); 1991: Job experience in Bruxelles, Belgium, in IVF Lab directed by Prof. R. Schoysmann (2 weeks) 1991: Job experience with Prof. J. Gordon (Mount Sinai Hospital, New York) in the Micromanipulation programmes (PZD, SuZI) in the IVF Lab of "Istituto Materno Infantile", University of Palermo, Italy (Director Prof. Ettore Cittadini); 1990: Fellowship in the IVF Lab (Prof. J. Gordon) at "Mount Sinai Hospital", New York, USA (2 months); 1989: Voluntary in the IVF Lab of the "Istituto Materno Infantile" University of Palermo, Italy;

Page 2 - Curriculum vitae of [ SURNAME, other names ]

For more information go to www.cedefop.eu.int/transparency/ europa.eu.int/comm/education/index_en.html eurescv-search.com/

Page 3 - Curriculum vitae of For more information go to / SURNAME, other names ] www.cedefop.eu.int/transparency/

europa.eu.int/comm/education/index_en.html eurescv-search.com/

Articles

• The combination of genetic variants of the FSHB and FSHR genes affects serum FSH in women of reproductive age A. La Marca, E. Papaleo, C. Alviggi, G. Ruvolo, G. De Placido, M . Candiani, E. Cittadini, F. De Michele, V. Moriondo, V. Catellani, A . Volpe, and M . Simoni. Hum. Reprod. (2013) 28(5): 1369-1374

• New molecular markers for the evaluation of gamete quality. Ruvolo G, Fattouh RR, Bosco L., Brucculeri A M , Cittadini E.J of Assist Reproduct and Genet Volume 30, Issue 2 (2013), Page 207-212

• Lower sperm dna fragmentation after r-fsh administration in functional hypogonadotropic hypogonadism. Ruvolo G, Roccheri,MC, Brucculeri A M , Longobardi S, Cittadini E, and Bosco L. J Assist Reprod Genet (2013) 30:497-503

• Sperm head vacuolization affects clinical outcome in ICSI cycle. A proposai of a cut-off value. Doriana Falagario, Anna Maria Brucculeri, Raffaella De Palo, Paolo Trerotoli, Ettore Cittadini and Giovanni Ruvolo. J. Assist. Reprod.Genet. Volume 29, Issue 11 (2012), Page 1281-1287

•Treatment of patient with high sperm D N A fragmentation levels. Journal of Clinical Medicine. Anno X V I - Voi 12 - Nr 6 June 2012

• Human papillomavirus infection in couples undergoing in vitro fertilization procedures: impact on reproductive outcomes.

Perino A , Giovannelli L, Schillaci R, Ruvolo G, Fiorentino FP, Alimondi P, Cefalù E, Ammatuna P. Fertil Steril. 2011 Apr;95(5): 1845-8. Epub 2010 Dee 17

• Ovarian stimulation protocol influences the apoptotic rate of human cumulus cells: a comparative study between recombinant and urinary human follicle-stimulating hormone (FSH). G. Ruvolo L. Bosco, E. Cittadini. Fertil.Steril. 92,nr.3,S242,suppl., 2009

Page 4 - Curriculum vitae of For more information go to [ SURNAME, other names ] www.cedefop.eu.int/transparency/

europa.eu.int/comm/education/index_en.html eurescv-search.com/

• R-FSH administration in idiopathic oligoasthenoteratospermic patients (iOAT) reduces the apoptotic rate in sperm cells. G. Ruvolo, F. Fornaro, L. Bosco, N . Colacurci,.E. Cittadini. Fertil.Steril. 92,nr.3,S72,suppl., 2009

• Il ruolo del ginecologo nel recupero e nel!' utilizzo delle cellule staminali. E. Cittadini, G. Barraco, A. Brucculeri, G. Ruvolo. Contraccezione Fertilità Sessualità, voi. 35, nr.2, 115-129,2008

• La preservazione della fertilità nel paziente oncologico. E. Cittadini, G. Barraco, M . Benigno, L. Blasi, E. Cefalù, R.A. Gancitano, E. Guastella, A . Lo Bue, M . Manno, G. Nasta, G. Ruvolo

• Lower apoptosis rate in human cumulus cells after administration of recombinant luteinizing hormone to women undergoing ovarian stimulation for in vitro fertilization procedures.

Giovanni RuvoloXiana Bosco. Antonina Pane. Giovanni Morici. Ettore Cittadini. Maria C. Roccheri.Fertil.Steril. Volume 87, Issue 3. Pages 542-546 (March 2007).

• Epigenetica e ART G. Ruvolo. Contraccezione Fertilità Sessualità 2006; 33,nr.4, 149-155

• Cryopreservation of biopsied embryos at the blastocyst stage Magli M.C. , Gianaroli L., Greco N . , Cefalù E., Ruvolo G. and Ferraretti A.P. Hum Reprod. 2006 Oct;21(10):2656-60. Epub 2006 Jun 12.

• Apoptosis in human unfertilized oocytes after intracytoplasmic sperm injection L. Bosco, G. Ruvolo, G. Morici, M . Manno, E. Cittadini and

M.C. Roccheri. Fert.Steril., vol.84, Nr.5, Nov.2005

• Il congelamento di ovociti allo stadio prò nucleare. A. Lo Presti, G. Ruvolo, R.A. Gancitano, E. Cittadini. Ovarian function following radiation and chemotherapy for cancer. G. Ruvolo, R. Gancitano:. 2PN Attuai Scient Biol Ripr (2004) 1: 1-27, 2004

• Fertility preservation in cancer patients. E. Cittadini, G. Ruvolo: Eur.J. obst.& Gyn. Repr.Med. 113S (2004). European Journal of Obstetrics & Gynecology and reproductive Biology, vol.H3,suppl.l, Aprii 2004.

Page 5 - Curriculum vitae of [ SURNAME, other names ]

For more informaiion go to www.cedefop.eu.int/transparency/ europa.eu.int/comm/education/index_en.html eurescv-search.com/

• Guest editor:Fertility preservation in Cancer patients; Serono Symposia international.European Journal of Obstetrics & Gynecology and reproductive Biology, vol.l 13,supplì, Aprii 2004.

• La preservazione della fertilità nelle pazienti oncologiche: il congelamento del tessuto corticale ovarico. R.A. Gancitano, G. Ruvolo, M . Manno, E.Guastella: Contraccezione, Fertilità Sessualità, vol.29,nr.5, Settembre 2002.

• Strategie terapeutiche e prelievo chirurgico degli spermatozoi. A. Armenio., M . Lamartina, G. Scalici, A. Lo Bue, M . Manno, G. Ruvolo. Contraccezione, Fertilità Sessualità, vol.29,nr.5, Settembre 2002.

• Effect of human sperm exposure to progesterone on sperm-oocyte fusion and sperm-zona pellucida binding under various experimental conditions. Francavilla F, Romano R, Santucci R, Macerola B, Ruvolo G, Francavilla S. Int J Andrai. 2002 Apr;25(2):106-12

• Il cromosoma Y . M . Manno, G. Ruvolo: Giornale Italiano di Ostetricia e Ginecologia. Vol.XXIII, Marzo 2001 • Genetic, andrological and clinical characteristics of patients with congenital bilateral absence of the vas deferens. Attardo T, Vicari E, Mollica F, Grazioso C, Burrello N , Garofalo MR, Lizzio M N , Garigali G, Cannizzaro M , Ruvolo G, D'Agata R, Calogero A E . Int J Andrai. 2001 Apr;24(2):73-9.

• Nitric oxide synthase inhibition in human sperm affects sperm-oocyte fusion but not zona pellucida binding. Francavilla F, Santucci R, Macerola B, Ruvolo G, Romano R. Biol Reprod. 2000 Aug;63(2):425-9.

• Coltura in vitro degli embrioni: scelta tra sistema semplice e complesso. R. Ciriminna, R. Palermo, E. Cefalù, G. Ruvolo, V. Agrifoglio,P.Napoli, E. Cittadini: Giornale Sifes, 1998;5:N.3

• La micromanipolazione nei programmi di P M A : del trattamento delle OAT alle azoospermie attraverso V analisi di 1755 cicli di microiniezione (ICSI). M.Manno, G. Ruvolo, E. Cefalù, R. Ciriminna, V. Agrifoglio, R. Palermo, E. Cittadini: Giornale Sifes,!998;5:N.3

Page 6 - Curriculum vitae of [ SURNAME, othernames ]

For more information go to www.cedefop.eu.int/transparency/ eu ropa.eu. int/comm/ed ucation/index_en. html eurescv-search.com/

MOTHER TONGUE

OTHER LANGUAGES:

Reading skills

• Writing skills

• Verbal skills

• Reading skills

• Writing skills

• Verbal skills

SOCIAL SKILLS

AND COMPETENCES Living and working with other people, in multicultural environments, in positions where communication is important and situations where teamwork is essential

(for example culture and sports), etc.

ORGANISATIONAL SKILLS

AND COMPETENCES Coordination and administration of

people, projects and budgets; at work, in voluntary work (for example culture and

sports) and at home, etc.

TECHNICAL SKILLS

AND COMPETENCES With computers, specific kinds of

equipment, machinery, etc.

Page 7 • Curriculum vitae of [ SURNAME, other names ]

• Cocoltures on vero cells for embryo selection after ICSI or embryo thawing. E. Cittadini, R. Ciriminna, R. Palermo, E. Cefalù, M.Manno, G. Ruvolo, P.Napoli, V . Agrifoglio: J. of Assist. Reprod. and -Genet.,Voi. 14,nr.5,1997(Supplement).

Books :

• La preservazione della fertilità nel paziente oncologico. E. Cittadini, G. Barraco, M . Benigno, L. Blasi, E. Cefalù, R.A. Gancitano, E. Guastella, A. Lo Bue, M . Manno, G. Nasta, G. Ruvolo • Manuale siuT esame del liquido seminale, Gli anticorpi

antispermatozoo (ASA).G. Ruvolo, A . M . Brucculeri. Percorsi Editoriali di Carocci Editore S.p.A., Roma, 39-46, 2013

ITALIAN

E N G L I S H

[ excellent]

[excellent ]

[excellent ]

FRENCH

[ basic]

[basic ]

[basic]

For many years has been involved in volunteering. In particular, by the age of 11 years I was involved in Scouting experience. I practiced team sports.

Excellent leadership, I have particular susceptibility to human and social relations, with excellent organizational skills. Enthusiastic, a team player, hard working, highly dextrous with exceptional attention to detail and have excellent communication skills

Large experience in clinical embryology, in celi cultures of human gametes, embryos and blastocysts Good user for Microsoft Windows Good use for MS Office Applications (Word, Excel, PowerPoint). High level of practice in IUl, IVF, ICSI, polar body, blastomere and trophoblast biopsy, sperm DNA fragmentation, in vitro maturation of human oocytes. High experienced also in laser management for assisted hatching procedures and time lapse embryo scoring by embryoscope and Primo vision. Experienced in oocyte/embryo vitrification and slow freezing

For more information go to www.cedefop.eu.int/transparency/ europa.eu.int/comm/education/index_en.html eurescv-search.com/

procedures. Excellent training in the management and quality control in the field ART procedures. Involved in the research activities in the field of biomarkers in selecting sperms, oocytes and embryos to increase the live birth rate in a eSET program

ARTISTIC SKILLS

AND COMPETENCES

Music, writing, design, etc.

OTHER SKILLS

AND COMPETENCES Competences not mentioned above.

DRIVING LICENCE(S) yes

ADDITIONAL INFORMATION References: Prof. Ri Chi Chian, Me Gill University, Montreal, Canada, rchian59(5)vahoo.ca Prof. Pasquale Patrizio, Yale University, New Heaven, CT, USA, Pasquale.Patrizio(S)yale.edu Prof. David Albertini, University of Kansas Medicai Center. USA, dalbertini@kumc.edu

ANNEXES

Page 8 - Curriculum vitae of For more information go to [ SURNAME, other names ] www.cedefop.eu.int/transparency/

europa.eu.int/comm/education/index_en.html eurescv-search.com/