28 issue toxenlaces - society of toxicology toxenlaces from the president p.1 ... speakers from...
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The Hispanic Organization of Toxicologists (HOT) is a Special Interest Group of the Society of Toxicology
ISSUE
April-May 2014
28 Toxenlaces From the President P.1
Our Members at the Annual Meeting P.2 2014 HOT Travel Award Recipients P.3
HOT Sister Organizations P.4 Article P.5
HOT Sponsors 2014 - 2015 P.6
HOT Annual Reception Memories P.7 HOT’s event to Students P.10
Note from the Editor P.11 Acknowledgment P.11 Announcements P.12
From the President
HOT Officers Contact
Betina Lew, Ph.D. President [email protected] Linval DePass, Ph.D. Vice President [email protected] Minerva Mercado-Feliciano, Ph.D., DABT Vice President elected [email protected] Elena Hernández-Ramón, M.D., Ph.D. Secretary [email protected] Ranulfo Lemus Olalde, Sc.D. DABT Treasurer [email protected] Betzabet Quintanilla, Ph.D. Councilor [email protected] Maria E. Gonsebatt, Ph.D. Councilor [email protected] Azita Cuevas, Ph.D. Councilor [email protected] René Viñas, Ph.D. Postdoctoral Representative [email protected] Catherine Rondelli, Ph.D. Graduate Student Representative [email protected] Leslie Recio, Ph.D. Past President [email protected]
Greetings HOT Members!!! This is the last newsletter before I retire as the
President of HOT-SOT. It has been a huge pleasure to serve as your leader in 2013-2014. I have enjoyed working with the HOT Board of Officers as councilor and Vice President since 2010.
This year is our 10th anniversary as Special Interest Group. It is so impressive to see the progress that has been made in our organization since then: the increased visibility and productivity of our members in the Society and the opportunities that have been created as a result of the foundation of HOT and its recognition as a SIG by the SOT.
And the progress continues. This year in the 53rd SOT Annual Meeting in Phoenix AZ, the HOT awarded 5 trainees of Latino origin with plaques and budget to attend the meeting. We had a new session in which HOT trainees had the opportunity of having breakfast and interacting on a “one on one” manner with several more experienced members of HOT and we co-chaired a brand new event titled “The Global Hot Topics Event” in which speakers from different parts of the globe (Brazil, Czech Republic and USA) discussed local air pollution and child development issues.
Our reception in the Annual Meeting was a tremendous success, with more than 100 people attending, it took place in the Arizona Latino Arts and Cultural Center. In a casual and friendly environment we were honored to have Dr. Gonzalo Diaz as the keynote speaker. Dr. Diaz is Professor
of Toxicology in the College of Veterinary Medicine, at the National University of Colombia, and is the award recipient of the “2014 Global Senior Scholar Exchange Program”. After our formal program and presentation of the travel awards, we mingled and had fun at the best Latino style: with plenty of food, drink, music and dancing!!!
I am very glad I had the opportunity of helping in making 2013-2014 a very productive year with lots of accomplishments for our organization. I would like to acknowledge one more time the wonderful Board of Officers with whom I worked with: Catherine Rondelli (Student Rep), René Viñas (Postdoctoral Rep), Jorge Muñiz Ortiz, Azita Cuevas, Betzabet Quintanilla-Vega (Councilors), María E. Gonsebatt (Councilor to Sister Organizations), Ranulfo Lemus Olalde (Treasurer), Elena Hernández-Ramón (Secretary), Minerva Mercado-Feliciano (Vice President-Elect), Verónica Ramírez Alcántara (Toxelances, Editor-in-Chief), Linval DePass (Vice President) and Leslie Recio (Past President). As always, I am available to each one of you, if you need any assistance.
I wish the best of lucks to the new HOT Board. I will be involved with them as Past President to keep working for our great organization.
THANK YOU, GRACIAS, OBRIGADA, for making HOT a huge success!!!!
Betina Lew, Ph.D. HOT President Building Bridges Through Toxicology
HOT keeps moving forward
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The participation of our members during the past SOT annual meeting was outstanding. Our camera captured some of them presenting their research work. Excellent job! We know you had a very successful meeting and we are sure we will see you again next year.
Our Members at the 53rd SOT Annual Meeting
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You already know them, but here they are receiving their plaque and check during the HOT Annual Reception at Phoenix AZ.
2014 HOT Travel Award Recipients
Vanessa Nuñez, undergraduate student from the University of California received the 2014 HOT Undergraduate Travel Award from Robert P. Casillas, Ph.D., ATS (MRI Global).
Alexandra Colón Rodríguez, Ph.D. student from Michigan State University received the 2014 HOT Travel Award from Azita Cuevas, MPH, Ph.D. (PepsiCo).
Rosa I. Rodríguez Cotto, Ph.D. candidate from the University of Puerto Rico received the 2014 HOT Travel Award from Ranulfo Lemus Olalde, Sc.D., DABT (Ingenieros Lemus de Mexico).
Ingenieros Lemus de Mexico
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Aline De Conti, Ph.D. Postdoctoral Fellow at the U.S. Food and Drug Administration National Center for Toxicological Research received the 2014 HOT Postdoctoral Travel Award from Kevin Kerze, Ph.D., DABT (Battelle).
Vinicius Carreira, Ph.D. candidate from the University of Cincinnati received the 2014 HOT Travel Award from Mari S. Stavanja, Ph.D. (Celanese).
AETOX – http://www.aetox.com Asociación Latinoamericana de Toxicología – http://www.alatox.org/qsomos/index.html Asociación Toxicológica Argentina – http://www.ataonline.org.ar Center of Environmental and Toxicological Research – University of Puerto Rico – http://cetr.rcm.upr.edu PLAGBOL – Salud, Agricultura y Medio Ambiente – http://plagbol.org.bo/noticias/enlaces Ritsq - http://www.ritsq.org Sociedade Brasileira de Toxicologia – http://www.sbtox.org.br/ Sociedad Cubana de Toxicologia Sociedad Mexicana de Toxicolgía – http://www.somtox.com.mx/ Society for Risk Analysis Latin America – http://www.srala.org/ Toxicología Acuática Ambiental, Medicina Veterinaria-Universidad Nacional de Colombia
http://www.docentes.unal.edu.co/jfgonzalezma Universidad de Cartagena – http://reactivos.com
HOT Sister Organizations
If your Hispanic Organization is planning a Toxicology meeting or you are organizing a Toxicology event intended for a primarily Hispanic audience, and want to promote it, send an email to René Viñas (incoming Toxenlaces Editor) at [email protected] for more information for its inclusion in upcoming issues.
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Article Nanotoxicology: Present and Future
as Global Emergent Field by José Francisco Delgado-Jiménez* and Teresa Palacios-Hernández*
*Universidad de las Américas Puebla, Puebla, México. Ex Hacienda de Santa Catarina Mártir S/N, San Andrés
Cholula Puebla, México. C. P. 72760. Phone +52 (1) 222-1761479. E-mail: [email protected], [email protected]
Nanotechnology, as an emergent discipline has grown as a multibillion-dollar industry worldwide. According to Wodrow Wilson Center (2014), over this year there have been produced more than 1600 nanotechnology enabled products, released to the environment in cosmetics, medical products, electronics, etc. Furthermore, there are many natural and anthropogenic sources of nanoparticles, and these materials can be unintentionally liberated as fumes, aerosols and ashes from incinerators, electric motors, internal combustion engines, etc.
During the 53rd SOT Annual Meeting the continued education courses were a great resource to get updated on different topics related to toxicological approaches. On this article we want to highlight the relevance of the continuing education course entitled “Nanotoxicology: Past Achievements, Future Challenges and Potential Solutions”. The lectures of this course were provided by Saber Hussain (chairperson, US Air Force, Wright-Patterson AFB, Dayton, OH), David Warheit (chairperson, DuPont Haskell Laboratories, Newark, DE), Laura Braydich-Stolle, Christin Grabinski (both from US Air Force), Kristen Comfort (University of Dayton) and Charles Geraci Jr. (NIOSH). They are well recognized in the field of nanotoxicology and introduced us to the most important aspects that should be prioritized when the toxicological effects of nanomaterials are considered.
Dr. David B. Warheit in his lecture entitled “Importance of Robust Nanomaterial Characterization as a Necessary Prerequisite for Evaluating the Results of In vivo Nanotoxicity Studies” showed the importance of performing an exhaustive physical/chemical characterization upon nanomaterials to determine aspects such as size, morphology, crystallinity, composition, aggregation state, particle surface reactivity, etc. These paramount parameters directly influence the toxicological effects that nanomaterials may have on in vitro or in vivo models subjected to exposure. Dr. Warheit compared the toxic effects of TiO2, ZnO and carbon nanostructures on lung tissue and on BALF cells. He emphasized that the knowledge of the applied or produced nanomaterial is crucial to understand their behavior on living beings and be able to detect their nanotoxic effects. The take home message was that if we want to publish an article in a toxicological journal presenting a nanomaterial with poor characterization, most probably the article will be rejected.
Laura K. Braydich-Stolle and Saber M. Hussain in their lecture entitled “Nanotoxicology: What has been done for the past Decade” described silver nanoparticles as a reference material and presented their in vivo and in vitro toxicological effects. Silver nanoparticles are of great relevance because they are broadly applied in the industrial sector. For example, they can be found in hygienic products (soap, toothpaste, shampoo, etc) and medical products (catheters and bandages). However, a direct correlation between the diameter of silver particles and their toxicity has been established. Some mentioned toxicological effects were lung and kidney damage and oxidative stress in mouse brain. Dr. Braydich-Stolle and Hussain mentioned that in the study of nanomaterial toxicity, the challenge is to define what factor made them toxic (dose, homogeneous uptake) or if the toxic effects are caused by nanoparticles or by the ions released by such nanomaterial.
Dr. Grabinski introduced us to the main concepts related to nanoparticle dosimetry. She explained the fundamentals of nanoparticle dosimetry challenges, such as alteration of physical/chemical properties, aggregation of nanoparticles and their interaction with biological components. Dr. Grabinski also talked about the approaches for comprehensive nanoparticle dosimetry, such as target dose, dose metric, dose methodology and characterization. She emphasized that for the delivery of nanoparticles to the target, realistic exposure methods and consideration of alternative exposure systems is important, and showed some in vivo and in vitro methodologies to determine the dose of nanoparticles that can reach the target
On lecture entitled “Unresolved Challenges: Biological Models and Future Directions Overcome these challenges”, Dr. Kristen K. Comfort discussed that it is necessary to improve the biological models employed to determine the toxicity of nanomaterials. There has been a broad development on the characterization, synthesis and dosimetry methodologies for nanoparticles. However, it is essential to perform more in vitro experiments that could simulate in vivo systems. Because there is a broad of differences between in vivo and in vitro models, she proposed to improve in vitro models with co-cultures, to use more type of cell lines, to perform 3-D in vitro models and to perform more experiments with more representative physiological environments.
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If you want to collaborate with short articles, news or notes related with Toxicology, send it to René Viñas (incoming Toxenlaces Editor) at [email protected] for inclusion in upcoming issues.
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Finally, Dr. Charles L. Geraci, with the lecture entitled “Occupational Hazards and Risks in the Workplace: Where We Stand”, discussed the problems related to pollution with nanomaterials in the workplace. He emphasized the urgent need to establish guidelines to prevent and control the exposure of human beings to nanomaterials, and the toxicological studies to evaluate their chronic effects in workplaces, their quantity on air, etc. Dr. Geraci addressed that, because of the nature of nanomaterials changes when they are released to the environment, it is urgent to obtain more information about nanomaterials in occupational sectors.
The relevance of the information provided by the speakers is broad considering that we all are exposed to toxicological agents at nanoscale level almost at daily bases. The United States of America and the European Union previously have established different rules and standards to detect, characterize and assess
the toxicology of nanomaterials in products of daily use and released in industrial emissions. However, in most Latin American countries these strategies are non-existent or are beginning to emerge, not to mention that the current regulatory limits might not be relevant at the nanometric level, because of the change of scale of the materials modifies their reactivity. Therefore, it is a priority, as representatives of the toxicology in Latin America, to join efforts and to establish regulations according to international standards, provided by the pioneers in nanotoxicology. Certainly, we have the duty to guide the society to find alternatives and strategies to regulate the issuance and evaluation of new pollutants, as the nanomaterials, whose properties are still not fully understood, to prevent their adverse effects on human health and the environment.
Ingenieros Lemus de Mexico
HOT Sponsors 2014-2015
If you are interested in being interviewed for the section When I Grow Up, please contact Azita Cuevas at [email protected]
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As every year, HOT reception was a success! The proof is in (eating) the pudding, so take a look on the series of pictures that our camera captured. If you attended it, you will remember those moments. If you didn’t attend, you are cordially invited for next year!
10th HOT Annual Reception’s Memories
The HOT celebrated 10 successful years with a grand reception at the Arizona Latin American Cultural Center. More than 100 HOT members, non-members and guests attended the reception were they got to know more about our organization, officers, awards and activities. Between good food and drinks, networking was top of the agenda that day.
Dr. Linval DePass (HOT Vice President, Durect Corp.) presenting his agenda for the period 2014 – 2015.
Dr. Gonzalo Diaz (University of Colombia) Keynote Speaker and winner of the 2014 Global Senior Scholar Exchange Program presenting his research in the field of mycotoxins.
Dr. Betzabet Quintanilla (CINVESTAV) updating on the activities by our sister organization (Sociedad Mexicana de Toxicología) and the upcoming International Congress of Toxicology to be held in Mérida, Yucatán (October 2016).
Dr. Silvia B. Moraes Barros (University of São Paulo) updating us on the upcoming 9th Congress of Toxicology in Developing Countries (CTDC) in Natal, Brazil (November 2015).
Dr. Peter Goering (SOT Vice President-Elect) saying a few words of support on behalf of the SOT council.
Dr. Betina Lew (HOT President, Church and Dwight, Corp.) giving her report for the goals reached by HOT during the period 2013-2014.
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Dr. Betina Lew (outgoing HOT President, Church and Dwight Corp.) with Dr. Arturo Andón Navarro (U. Complutense, Spain).
Directly from Puebla City, (Mexico), our camera captured Eddie Guillermo Sánchez Rueda, a Biotechnology Engineer student (UPAEP, Mexico).
Dr. Aline De Conti (left), one of the 2014 HOT Travel Award recipients enjoyed the reception together with Tanya Kobets.
Nice picture with Dr. Betina Lew (HOT President, Church and Dwight Corp.), Dr. Elena Hernández-Ramón (HOT Secretary, NIH), and Dr. Ofelia Olivero (HOT Past President, NIH).
Having a great time were (left to right): Katherine S. Squibb, Qin Zhang, and Girish Kumar.
A very pleasant evening had Dr. Esther López-Bayghen and Dr. Arnulfo Albores from CINVESTAV (Mexico).
Dr. Verónica Ramírez Alcántara (left) received a special recognition award from Dr. Betina Lew (right) for her work as the Editor in Chief of Toxenlaces, the HOT bi-monthly newsletter.
Dr. Betina Lew received a special recognition award from Dr. Linval DePass for her contribution as the 2013-2014 HOT President.
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Dr. Peter Goering (SOT Vice President-Elect) and Dr. Pedro Del Valle having a test of the good food and drinks, while enjoying the evening.
HOT reception is always a good event to see friends again as this group did (left to right): Dr. Edith Estela Uresti (UASL, Mexico), Dr. Elena Hernández-Ramón (HOT Secretary, NIH), Dr. Claudia Escudero (UASL, Mexico) and Dr. Azita Cuevas (HOT Councilor, Pepsico).
Our incoming Postdoctoral Repre-sentative, Dr. Teresa de Jesús Palacios Hernández (UDLAP, Mexico) enjoying the reception together with José Francisco Delgado Jimenez (left) (UDLAP, Mexico) and Eddie Guillermo Sánchez Rueda (UPAEP, Mexico).
Dr. Linval DePass (HOT Vice President, Durect Corp.) with Keynote Speaker Dr. Gonzalo Diaz (University of Colombia).
No HOT meeting is complete without a bit of dancing!
After receiving her award, Rosa I. Rodríguez Cotto (front) (University of Puerto Rico) enjoyed the reception together with Jarline Encarnación (center) (University of Puerto Rico) and Julieta Martino (back) (University of Southern Maine).
Dr. Pedro Del Valle (left) (HOT Past President, FDA) and Dr. Xavier Arzuaga in company of a good friend of HOT.
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Team Work!
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The successful presence of the HOT on the 53rd SOT Annual Meeting at Phoenix AZ was nothing but the result of team work! Thanks to all the members involved in planning and organizing all our activities for the meeting. Good job!!
It is time the world knows about you!! We are looking for outstanding Hispanic trainees to be feature in Toxenlaces. If you are that trainee or if you want to nominate somebody, send your/her/his biography and picture to René Viñas (incoming Toxenlaces Editor) at [email protected] for inclusion in upcoming issues.
HOT’s Event to Students and Trainees members During the past SOT Annual Meeting, the HOT organized a breakfast
event focused on the different career paths available for toxicologists. This was a great opportunity for our students and trainees to get information about how to leverage opportunities and strength areas throughout the job hiring process and early career life, and to know about training opportunities available at the National Institutes of Health for trainees of minority origin. If that was not enough, those presentations were followed by roundtable discussions in which mentees had the opportunity to xxxxxxx
directly interact with mentors of Latino origin from a variety of sectors including industry, government, and academia. This event was hosted by Dr. Betina Lew (HOT President, Church and Dwight, Corp.) and Dr. Elena Hernandez-Ramon (HOT Secretary, NIH). The round tables were presided by Dr. Azita Cuevas (HOT Councilor, Pepsico), Dr. Pedro del Valle (HOT Past President, FDA), and Dr. Mari S. Stavanja (Co-Founder and HOT Past President, Celanese).
Note From the Editor
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Dear HOT members, This is my last issue of Toxenlaces as the Editor-in-Chief. It has been a pleasure to serve you by releasing every two months this newsletter to keep you informed about what is going on in our organization. I hope you enjoyed reading each edition. During this time as Editor I got to meet a lot of our members, if not in person but by
If your Hispanic Organization is planning a Toxicology meeting or you are organizing a Toxicology event intended for a primarily Hispanic audience, and want to promote it, send an email to René Viñas (incoming Toxenlaces Editor) at [email protected] for more information for its inclusion in upcoming issues.
email, and not only from United States, but also from Mexico, Brazil, Spain; so base on that I could say that I traveled a lot!! I also was able to re-connect with old friends, as for example René Viñas, I met him in 2005, and because of Toxenlaces I met him again two years ago. In fact, René will be the new Editor-in-Chief of our bi-monthly newsletter. I know he will continue delivering valuable material to us with news from our members, interviews from recognized Hispanic toxicologists and scientific articles from our community.
I want to express my gratitude to all those that helped me during my position, especially to Minerva Mercado-Feliciano (past Editor), who trusted on me for this role and trained me to be a good one. Thank you also to all those members that collaborated with Toxenlaces by being interviewed or sending me material to be published. Keep enjoying Toxenlaces! Verónica Ramírez Alcántara, Ph.D. Editor-in-Chief, Toxenlaces HOT
Acknowledgment Special thank you goes to José Francisco Delgado Jimenez and Teresa de Jesús Palacios Hernandez, for capturing with their camera the special moments of our organization during the 53rd SOT Annual Meeting. All the pictures used on this edition of Toxenlaces come from them.
José Francisco is a HOT member from Mexico, who received his B.Sc. degree in Nanotechnology and Molecular Engineering from the Universidad de Las Americas Puebla, at Mexico. He presented a poster with his thesis’ data entitled: “Preparation, Characterization and Antimicrobial Activity of Eu3+-Doped Hydroxyapatite Nanopowders”. Jose is planning to apply in USA for a Ph.D. program on Nanomaterials for Medical Applications.
Dr. Palacios is the incoming HOT Postdoctoral Representative. She is from Mexico and received her Doctoral degree in Chemical Sciences from the Benemérita Universidad Autónoma de Puebla. Currently she is a Postdoctoral Fellow in the Department of Food and Chemical Engineering at Universidad de las Americas Puebla (UDLAP), Mexico. Dr. Palacios has focused her research on Nanotoxicology, studying the synthesis, characterization and biological in vitro activity of surface-modified metal oxide nanoparticles and the synthesis, characterization and antimicrobial activity of polymeric nanocapsules containing natural active ingredients employed in medicine. She has served as adjunct professor at UDLAP and Universidad Popular Autonoma del Estado de Puebla (UPAEP), supporting bachellor programs such as medicine, biotechnology engineering and nanotechnology. Her student Eddie Guillermo Sánchez Rueda presented a poster during the meeting entitle: Preparation and Antimicrobial Activity of Nanocapsules Containing Extracts of Catharanthus roseus and Matricaria chamomilla. José Francisco and Dr. Palacios are the authors of the article in the area of nanotoxicology, published in this issue of Toxenlaces (pag. 5).
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HOT wants you to be part of the organization! To make it available to everyone, HOT accepts applications from non-SOT members to become HOT members. Yes, that is right!! You only have to have the desire to collaborate with and be part of our great organization.
Your HOT membership provides you with valuable resources throughout your scientific career as for networking through the largest Hispanic toxicologist community, giving you opportunity for Travel Awards or serving as a mentor to the young Hispanic toxicologists; besides you receive the Toxenlaces newsletter every two months.
Application and more information can be found at Non-SOT Member Application. So, what are you waiting for? We are looking forward to receiving your application today!!
The Sociedad Mexicana de Toxicología (SOMTOX), in combination with IUTOX, is holding the XIV International Congress of Toxicology in October 2016. This is the first time that an International Congress of Toxicology will be held in Mexico, and in Latin America, so what a better way to celebrate such event that having it in the beautiful city of Mérida, Yucatán, the gateway to the Mayan World. The Congress will be a “green” event with the theme: “Toxicology and Global Sustainability”. You can found more information on page 13 or at http://www.ict-mexico2016.org
The Hispanic Association of Colleges and Universities (HACU) represents approximately 450 colleges and universities committed to Hispanic higher education success in the U.S., Puerto Rico, Latin America and Spain. The HACU is celebrating its 28th Annual Conference, “Championing Hispanic Higher Education Success: Investing in America's Future", It will be held on October 4-6, 2014, at the Sheraton Denver Downtown Hotel in Denver, Colo. The HACU conference annually attracts hundreds of corporate, federal, and non-profit employers along with colleges and universities, all eager to talk to undergraduate students. The HACU Student Track program serves as a forum for undergraduate students to ask questions about careers and career development. A limited number of Student Track Scholarships are available to eligible students to attend the HACU conference. The Scholarship will cover costs for: the conference registration; travel and lodging for out-of-state students; and one conference-related meal per day. To be considered for a conference scholarship, students must complete the 28th Annual Conference Scholarship on-line application. The application deadline is June 27, 2014. For more information visit http://www.hacu.net/hacu/Conference_Student_Scholarship1.asp
Announcements
Follow us 24/7 on Facebook at: http://www.facebook.com/hispanicorganizationoftoxicologists. Don’t forget to visit also the SOT Facebook page: http://www.facebook.com/pages/Society-of-Toxicology-SOT/163627880427831?fref=ts
Toxenlaces is the newsletter that informs Hispanic toxicologists in the United States and the international Spanish and Portuguese-speaking scientific communities about important toxicological events and issues occurring in our countries. It is electronically published and distributed to our membership and Sister Organizations in Ibero-America. Toxenlaces disseminates critical dates for events, health perspectives, and funding and training opportunities. It serves as a toxicology forum for our members and other partner organizations, engages in educational outreach to the Hispanic communities and provides the essential elements to support networking among Hispanic toxicologists.
Toxenlaces is open to receive collaborations from HOT and SOT members, and Sister Organizations. You can collaborate with short scientific articles, news or notes related with toxicology. Other ways to collaborate is by nominate your peers or yourself for the sections Featured Trainee and When I Grow Up. For more information about collaborating with Toxenlaces send an email to René Viñas (incoming Toxenlaces Editor-in-Chief) at [email protected]
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