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1 DOCTORAL PROGRAM Course work (Common Scheme for SET, SOM, SOC, SBA, SPA candidates) Subject Code Subject Name Teaching Scheme (Hrs per week) Credits Marks Lecture Tutorial Practic al Common Courses PD101EN101 Research Methodology 4 - - 4 100 PD101EN102 Writing & Presentation Skills in Research 4 - - 4 100 PD101EN103 Mathematics for Research 4 - - 4 100 Candidate Specific Courses PD101EN104 Area Specific Course - - 4 4 100 PD101EN105 Review Paper & its Presentation - - 4 2 100 TOTAL 12 8 18 500

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1

DOCTORAL PROGRAM Course work

(Common Scheme for SET, SOM, SOC, SBA, SPA candidates)

Subject Code Subject Name

Teaching Scheme (Hrs per week)

Credits Marks Lecture Tutorial Practic

al Common Courses

PD101EN101 Research Methodology 4 - - 4 100

PD101EN102 Writing & Presentation Skills in Research

4 - - 4 100

PD101EN103 Mathematics for Research 4 - - 4 100

Candidate Specific Courses PD101EN104 Area Specific Course - - 4 4 100

PD101EN105 Review Paper & its Presentation

- - 4 2 100

TOTAL 12 8 18 500

2

Common Marking Scheme

Subject Code Subject Name Assignment (a)

MSE (b)

Total IA (c=a+b)

ESE (d)

Total (e=c+d)

Common Courses

PD101EN101 Research Methodology

10 20 30 70 100

PD101EN102 Writing & Presentation Skills in

Research 10 20 30 70 100

PD101EN103 Mathematics for Research

10 20 30 70 100

Candidate Specific Courses PD101EN104 Area Specific Course - 50 50 50 100

PD101EN105 Review Paper & its Presentation

- 50 50 50 100

TOTAL 30 60 190 310 500 Objective of Course Work: 1. The objective of this course work is to familiarize the doctoral research candidates the process of

research, Mathematical Concepts needed for research, Report Preparation & presentation, and the concepts needed from their own area of research.

2. To train them through practice in reference to reading, analyzing, summarizing a research paper, writing a review paper in their own area.

3. To get the work of exhaustive literature review done during the course work, so as to defend the problem statement in the final presentation of Thesis title while end term seminar.

3

DETAILED SYLLABUS: Doctoral Program Course Work

School of Basic and Applied Sciences

1.1.1 Research Methodology Code: PD101EN101 4 Credits [LTP: 4-0-0]

A. OUTLINE OF THE COURSE

B. DETAILED SYLLABUS

Unit No. Title of the unit Minimum number of hours 1. Overview of Research Methodology 2. Data Collection & Presentation 3. Review of Basic Statistical Measures 4. Design and Analysis of Experiments 5. Attitude Measurement & Scales 6. Probability Distributions 7. Testing Hypothesis I & II 8. Basic Multivariate Analysis 9. Advance Multivariate Analysis 10. Algorithmic Research 11. Simulation

Unit Contents 1. Overview of Research Methodology

Introduction, Mathematical tools for analysis, Research problems in management, Types of research, Research Process

2. Data Collection & Presentation Introduction, Primary data, Secondary data, Data Presentation

3. Review of Basic Statistical Measures Introduction, Measures of Central Tendencies, Measures of Variation, Measures of Skewness

4. Design and Analysis of Experiments

Introduction, Analysis of Variance, Completely Randomized design, Randomized complete block design, Latin square design, Duncan’s multiple Range Test, Functional design, second factorial experiment, Expected Mean Square.

5. Attitude Measurement & Scales

Introduction, Measurement, Fundamentals of Data Collection Methods, Types of scales, Scales for Stimuli, Scaling Respondents,

6. Probability Distributions Introduction, Approaches to Probability, Probability Distribution 7. Testing Hypothesis I & II

What is Hypothesis, Basic Concept of Hypothesis and Testing, Procedure, Flow Diagram, Measuring the Power of Test, Tests, Important parametric Tests, Hypothesis testing Means, differences, comparison, Proportion Testing, Differences, Important Non Parametric or Distribution Free Test, Relationship between Spearman’s r’s and Kendall’s W, Characteristics

8. Basic Multivariate Analysis Introduction, Correlation analysis, Forecasting, Linear regression & Time series

9. Advance Multivariate Analysis Introduction, Discriminate Analysis, Factor Analysis, Terminologies & Methods of Factor Analysis, Clusters

Analysis 10. Algorithmic Research Introduction, Algorithmic Research Problems, Types, Types of Solution Procedures, Steps of development,

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C. RECOMMENDED STUDY MATERIAL:

S.No Title of the Book Author 1. Research Methodology R. Panneerselvam, PHI 2. Research Methodology: Methods and Trends Dr. C. R. Kothari 3. Research Methodology: A Step by Step Guide for Beginners Ranjit Kumar

4 The Principles of Experimental Research, by K. Srinagesh Elsevier

5 DRM, a Design Research Methodology

By Lucienne T. M. Blessing, Amaresh Chakrabarti Springer

1.1.1.1 Writing & Presentation Skills Code: PD101EN102 Credits [LTP: 4-0-0]

C. OUTLINE OF THE COURSE

D. DETAILED SYLLABUS

Steps of Algorithmic Research, Design of Experiments, Meta Heuristics for Combinational Problems. 11. Simulation Introduction, Need for simulation, Types, Simulation Languages, case study.

Unit No. Title of the unit Minimum number ofhours 1. Literature survey 2 2. How to study a scientific paper 8 3. Publishing a paper 8 4. How to present scientific paper 8 5 Technical / Seminar Report Writing 2

Unit Contents 1. Literature survey

Overview – What is literature survey, Functions of literature survey, maintaining a note book, developing a Bibliography Methods of data collection – Observation, survey, contact methods, experimental, determining sample design Searching for publications – Publication databases, search engines and patent data bases, Find some/all of the references for a given paper, including those that are not on the webOnline tools – google, CiteSeer, ACM Digital Library, IEEE, The on-line ComputerScience bibliography, Survey papers, Finding material not on the web, Searching patents

2. How to study a scientific paper Summarizing paper – Reading abstracts and finding ideas, conclusion, Advantages oftheir approach, the

drawbacks of the papers (What is lacking – can be found in thesections such as future work) Generalize results from a research paper to related researchProblems. Comparing the approach - Identify weaknesses and strengths in recent research articles in the subject

3. Publishing a paper How to write scientific paper Structure of a conference and journal paper, how (and How Not) to write a Good

Systems Paper: Abstract writing, chapter writing, discussion, conclusion, references, bibliography, and In-class discussion of technical writing examples, Poster papers, review papers, how to organize thesis Project report, How to write a research proposal? How research is funded? Research ethics – Legal issues, copyright, plagiarism General advice about writing technical papers in English Tips for writing correct English

4. How to present scientific paper Talk structure, basic presentations skills Documentation and presentation tools LATEX, Microsoft office,

PowerPoint and SLITHY

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C. RECOMMENDED STUDY MATERIAL:

S.No Title of the Book Author 1. As discussed in the class 2. 3.

1.1.1.3 Mathematics for Research Code: PD101EN103 4 Credits [LTP: 4-0-0]

A. DETAILED SYLLABUS

B. RECOMMENDED STUDY MATERIAL:

S.No Title of the Book Author 1. Fundamentals of Mathematical Statistics by Gupta S. C. and Kapoor V. K., S. Chand Publication 2. Fundamentals applied Statistics by Gupta S. C. and Kapoor V. K., S. Chand Publication 3 Stochastic Processes by J. Medhi, Wiley Publication 4 Operation Research by S. Rao

5 Technical / Seminar Report Writing Structure & Requirements for Seminar Report, Review Report, Dissertation

Unit Contents Unit I Basic Mathematics

Differential Calculus: Functional relationships between two variables, Introduction to limits, Continuity, & differentiability, standard results for differential coefficients of xn, ex, log x etc. Rules for differentiation of sum, difference, product & quotient and function of a function, Maxima & Minima of functions of One & two variables. Integral Calculus: Definition and meaning of Integration, Integration as inverse of differentiation, Indefinite Integral, Integral of Simple function, Integration by substitution, integration by parts, definite Integral & its properties, Beta & gamma Integral & Their properties.

Unit II Statistical Measures: Central Tendencies, Dispersion, Moments, Skewness & Kurtosis. Unit III Probability: Distribution function, Mathematical Expectation, Bionomial, Poission & Normal

Distribution. Unit IV Correlation & Regression Analysis: Curve fitting, Coefficient of Correlation, its properties, Bivariate

and Multivariate regression, Linear & Nonlinear regression.. Sample Survey: Concept of population and sample, probability & Non probability sampling, Simple

Random Sampling, Stratified Sampling & Systematic Sampling. Unit V Testing of Hypothesis: Statistical Hypothesis, Simple & Composite, Null Hypothesis, Alternative

Hypothesis, Critical Region, Two types of errors, Level of Significance, NP Test, Power of Test and Relative problems.

Unit VI Small and Large Sample Tests: Estimation of parameters, Maximum Likely hood Method, Point Estimation and Interval Estimation, Chi Square, t-test, f-Tests.

Unit VII Non Parametric Tests: Difference between Parametric & Non Parametric Tests, Sign Test, Run Test, Median Test, Wilcoxon-Mann-Whitney Test.

Unit VIII Statistical Quality Control: Meaning and Definition, Chance & Assignable causes of variation, Control Charts for variables X- bar, R & S Charts, Control Charts for attributes: d, p and c Charts. Single and Double Sampling Inspection Plans, OC and ASN Curves.

6 1.1.1.4 Area Specific Topics Code: PD101EN104

4 Credits [LTP: 4-0-0]

A. PHYSICS (Candidate will have the option to select any five units from the following list of units as per specialization or may submit any other relevant topic in coordination with the supervisor)

Unit Contents Unit I Basic Measurements: Evaluation of Measurements: Errors; Normal, Binomial and Poisson

distribution; Least square fit; Curve, fitting, Polynomials; Chi-square test. Length and Related Quantities: Rutherford Experiment (Nuclear Size); X‐ray, Electron and Neutron diffraction. Voltage, Current and Charge Measurements, Magnetic Field: Magnetic Materials; Production and Measurement of Magnetic Fields. Temperature: Production and Measurement of High and Low Temperatures, High temperature materials.

Unit II Experimental Methods: Vacuum Technology; Production and Measurement of Rough to Ultra High Vacuum; Design of vacuum systems; Leak detection methods, Vacuum Materials. Thin Film Technology: Synthesis of thin films for research and technological applications. Ion Beam Techniques: Synthesis, Modification and Processing of novel Materials; Ion beam analysis‐ SIMS, RBS, Channeling, ERDA. Modern Analytical Tools: AES, XPS, TEM, SEM, FTIR spectroscopy, Raman spectroscopy, ESR, PL, STM, AFM. Great Experiments in physics: Any two great experiments suggested by the teacher concerned not covered in the syllabus.

Unit III Semiconductor Physics: Crystal structure and Band structure: Study of crystal structure and band structure of silicon, germanium and gallium arsenide semiconductors. Properties of Semiconductors: Charge carriers in semiconductors, Hall Effect: Magneto resistance; Hot carriers; Quantum Hall effect. Thermal effects in semiconductors, Fundamental, impurity, free carrier and exciton absorption. Radiative and surface recombination. Photoconductivity. Optical processes in quantum wells; Laser action in semiconductors. Advanced and Novel Electronic Materials: Amorphous Si, Ge and Ga, As, Organic semiconductors, Spintronics materials, Dilute magnetic semiconductors; Semiconductor quantum wells, quantum wires and quantum dots; Semiconductor nanocrystals. Surfaces and Interfaces: Surface states, Interface states in semiconductor devices; Characterization of semiconductors and devices by I‐V, C‐V, G‐V and DLTS techniques. Ultra Large Scale Integrated circuit (ULSI) device technology: Semiconductor bulk crystal Growth, Epitaxy, defects, dislocations and doping in semiconductors, Basic device fabrication processes, Circuit design and fabrication.

Unit IV Modern Electronics: Microcontroller: Introduction to microcontroller, microcontroller, MCS Architecture, Registers, pin description, Connections, I/O ports, Memory organization, Addressing modes, Instruction set, Stack pointer, Assembly language programming, Development systems and Tools, Software simulator, Interrupts, Timer and Counter, Serial communication, Atmel microcontrollers (89C51 / 89C2051), Architectural overview, Pin description (89C51 / 89C2051), Applications of MCS – 51 and 89C51 / 89C2051, PIC microcontroller – overview, Memory organization and Instructions, Addressing modes, I/O ports, Interrupts in PIC 16C61/71, PIC 16C61/71 timers, PIC 16C61/71 – ADC, PIC 16F8XX flash microcontroller, Interfacing and microcontroller applications, Industrial applications of microcontrollers. HDL: Basic terms in VHDL, Behavioral modeling, Types of delay, Sequential processing, Data types, Function and Procedure, Attributes, Configurations. Embedded system: Introduction to embedded system, Design challenges, Optimizing design metrics, Processor design and IC technology, Embedded system project management, Embedded system design and co‐design isues in system development process, Design cycle in the development phase for an embedded system. Use of software tool for development of embedded system PC interfacing: Study of PC parallel port: Essentials, Accessing ports, Programming issues, Programming tools, Experiments and interfacing, Study of PC serial port: Format and Protocol, Sending serial Data, Transmitting a byte, Data Formats, Preventing missed data, Port architecture, Port resources, Configuring inside the UART.

Unit V Nanotechnology: Fundamentals of nano-materials and nanostructures, Synthesis of nano particles, nano clusters, nano crystals; top‐up approach and bottom‐up approach, Self‐Assembly. Properties of Metal Nano-clusters, Semiconducting Nano-particles, Rare Gas and Molecular Clusters and Nanotubes. Characterization of nano-materials and nanostructures: structure, particle size, distribution. Applications of nanotechnology in Semiconductor devices, Energy, Sensors, Coatings.

Unit VI Accelerator Physics: Introduction to Accelerators; Types of Accelerators: High voltage dc and r. Accelerators, Cyclotron, Ion Sources: Freemen ion beam source, Penning ion source,

7

RECOMMENDED STUDY MATERIALS

Sputtered ion source, Duo plasmatron ion source, Negative ion beam sources, Electron Cyclotron Resonance (ECR) ion beam sources, LASER ion source. Beam switch yard: conventional magnet and superconducting magnet Beam optics, Beam profile monitor, Faraday cup, Quadruple. Accelerator driven systems: Injection and extraction, Vacuum systems. Application of accelerators: Ion implantation, Surface modifications and research, Materials analysis, Nuclear physics, High energy Physics studies, Production of medical isotopes, Radiotherapy, Radiation and Safety.

Unit VII Nuclear Physics: Nuclear Structure: Problem of Nucleon –Nucleon Interactions and Nuclear Forces, Nuclear Models and Nuclear Matter, Electromagnetic and Weak Interactions with Nuclei. Nuclear Reactions: Formal theory of Scattering and Nuclear Reaction Mechanisms, Compound Nuclear Reactions, Optical Model and Direct Nuclear Reactions, Nuclear Reactions at Intermediate and High Energies. Methods in Experimental Nuclear Physics

Unit VIII Laser and Plasma Physics: Fundamentals of Laser: Laser Raman Spectroscopy, Holography, New Developments in Spectroscopy, Applications. Fundamentals of Plasma: Magneto hydrodynamics (MHD), Space Plasma Physics, Transport properties in Plasma, Applications.

Unit IX Materials Science: Introduction to Materials Science: Classification of Materials, Functional Classification of Materials, and Classification of Materials Based on Structure, Environmental and Other Effects, Materials Design and Selection. Atom and Ion Movements in Materials: Applications of Diffusion, Stability of Atoms and Ions, Mechanisms for Diffusion, Activation Energy for Diffusion, Rate of Diffusion (Flick’s First Law), Factors Affecting Diffusion, Permeability of Polymers, Composition Profile (Flick’s Second Law), Diffusion and Materials Processing. Chemical Equilibrium, Rate of Reaction, First and Second order Phase Transformation, Order‐Disorder Transformation, Solid State Sintering. Solid Solutions and Phase Equilibrium: Phases and the Phase Diagram, Solubility and Solid Solutions, Conditions for Unlimited Solid Solubility, Solid‐Solution Strengthening, Isomorphous Phase Diagrams, Relationship Between Properties and the Phase Diagram, Solidification of a Solid‐solution Alloy, Non equilibrium Solidification and Segregation, Nucleation and Rate of Phase Transformation

Unit X Condensed Matter Physics: Physical applications of Group theory in crystals: Theory of group representation, crystal symmetry operators; Crystallographic point groups. Representation of three dimensional rotation groups. Crystal field splitting and other related problems. Elastic Scattering of waves: Interference of Waves, Elastic scattering by Crystals, Experimental Techniques, Scattering from surfaces, Scattering from amorphous solids Magnetic Properties: Background, Diamagnetism and Para magnetism, Ferromagnetism, Ferri and anti ferromagnetism, Spin waves, Magnetic resonance Phenomenon.

Unit XI Theoretical Physics: This paper is envisaged as applications of Quantum Mechanics to physical systems through problems: Formalism in quantum mechanics, Time dependent perturbation theory, Relativistic Quantum Mechanics, Scattering Theory.

Unit Title of Books Unit I 1. “Errors of Observation and their Treatment” by J. Topping, Chapman of Hall, London 1972.

2. “Elements of X‐ray diffraction”, by B. D. Cullity, Addison‐Wesley Publishing company inc., 1977. 3. “Methods of Experimental Physics Vol. 2” by L. Marton (ed), Academic Press, New York, 1981. 4. “Introduction to Magnetic Materials” by B. D. Cullity, Addison Wesley Publishing Company, 1974. 5. “Temperature” by T. J. Quinn, Academic Press, London, 1983.

Unit II 1. “Vacuum Technology” by A. Roth, North Holland, Amsterdam, 1982. 2. K.L. Chopra, Thin film phenomena, Mc‐Graw Hill, New York, 1969. 3. “Ion Implantation” by G. Dearnaley, J. H. Freeman, R. S. Nelson,. and J. Stephen, North‐Holland, Amsterdam, 1973. 4. L. C. Feldman and J.W. Mayer, Fundamentals of surface and Thin Films Analysis, North Holland, Amsterdam, 1986. 5. Great Experiments in Physics, M. H. Shamos, Dover Publication, 1987.

Unit III 1. R.A. Smith, Semiconductors, 2nd edition; Cambridge University Press, London, 1978. 2. Jasprit Singh, Physics of Semiconductors and their Heterostructures, McGraw‐Hill, New York,1993, 3. M.H. Brodsky (ed), Topics in Applied Physics Vol.36, Amorphous Semiconductors, 4. S.R. Elliott, Physics of Amorphous Materials, Longman, London, 1983, 5. E.L. Wolf, Nanophysics and Nanotechnology, Wiley‐VCH Verlag, Weinheim, 2004. 6. S.M. Sze, Physics of Semiconductor Devices, John Wiley, N.Y., 1981, 7. E. H. Nicollian an J.R. Brews, MOS Physics and Technology, John Wiley, 1982, 8. S.M. Sze, Semiconductor Devices‐Physics and Technology, John Wiley, 1985

Unit IV 1. Microcontrollers – Theory and Applications, Ajay V Deshmukh. Ch. 1 to 10, 12,13. 2. VHDL Programming by example, Douglas L. Perry. Ch. 1 to 7.

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3. Embedded system design – a unified hardware, software introduction Frank Vahid and Tony Givargis Ch.1. 4. Embedded system design – Raj Kamal. Ch. 12.1 to 12.3, 12.5 5. Parallel port complete – Jan Axelson. Ch. 1 to 6 6. Serial port complete ‐‐ Jan Axelson. Ch. 2,3

Unit V 1. Introduction to Nanotechnology, C. P. Poole and F. J. Owens Pub Wiley & Sons, 2006. 2. Nanostructures & Nanomaterials, Synthesis Properties & Applicatios, G. Cao, Imperial Press, 2006. 3. Springer Handbook of Nanotechnology, Bharat Bhusan, 2004.

Unit VI 1. S Y Lee, Accelerator Physics, [World Scientific 1999 ] 2. Edmund Wilson, An Introduction to Particle Accelerators, [Oxford University Press 2001] 3. Alex Chao, Handbook of Accelerator Physics and Engineering [World Scientific 1999] 4. Mario Conte and William W McKay, An Introduction to the Physics of Particle Accelerators, [World Scientific 1991] 5. Ashok Das and Thomas Ferbel, Introduction to Nuclear and Particle Physics [John Willey 1994] 6. J.F. Ziegler, Ion Implantation Science and Technology, 7.G. Dearnaley, J.H. Freeman, R.S. Nelson, and J. Stephen, Ion implantation, North Holland, Amsterdam 1973.

Unit VII 1. Nuclear structure, M. A Preston and R. K. Bhandhuri, Addition Wesley (1975). 2. Nuclear Physics: R. Roy and B. Nigam – Wiley Eastern Ltd. (1979). 3. Fundamentals of Nuclear Physics – N. A. Jelly, Cambridge University Press. 4. Introductory Nuclear Physics – Samuel S. M. Wong, Prentice Hall of India (1996). 5. Nuclear models, Greiner and Maruhn: Springer Verlag. 6. Nuclear Reactions—Daphne F. Jackson, Chapman and Hall. 7. Nuclear and Particles – E. Segre 8. Nuclear Physics, HA Enge 9. Techniques for Nuclear and Particle Physics Experiments, W.R.Leo, Springer – Verlag, II edition.

Unit VIII 1. Lasers: Theory & Applications, A.K. Ghatak 2. Optoelectronics Devices & Systems, S.C. Gupta 3. Space Plasma Physics, A.C. Das 4. Laser Spectroscopy, W. Demtroder (Springer) 5. Introduction to Plasma Physics & Controlled Fusion, F. F. Chen 6. The Physics of Laser & Plasma Interactions, W.L. Kruer 7. Industrial Plasma Engineering, J. Reece, Roth 8. Introduction to Plasma Theory, D. R. Nichalson 9. Plasma Physics, R. Dendy

Unit IX 1.The Science and Engineering of Materials, 5th ed, Donald R. Askeland and Pradeep P. Phulé, Thomson Learning 2006. 2.Science of Materials Engineering, 2nd Edition, C. M. Srivastava and C. Srinivasan, (New Age International), 2005

Unit X 1. M. Tinkham, Group Theory and Quantum Mechanics, Dover Publications, 2003 2. N.W.Ashcroft and N.D. Mermin, Solid State Physics, Brooks Cole, 1976 3. J. Richard Christman, Solid State Physics, John Wiley, 1988

Unit XI 1. Richard Liboff, Introductory Quantum Mechanics, 4th ed., 2003. 2. Ajoy Ghatak and S Lokanathan, Quantum Mechanics: Theory and Applications, 5th ed., 2004. (GL5) 3. W. Greiner, Quantum Mechanics: An Introduction, 2nd ed., 2001. 4. R. Shankar, Principles of Quantum Mechanics, 2nd ed., 1994 5. L.I. Schiff, Quantum Mechanics, 1968 6. Claude Cohen ‐ Tannoudji, Bernard Diu, Frank Laloe, Quantum Mechanics Vol I and II, 1977.

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B. CHEMISTRY (Candidate will have the option to select any five units from the following list of units as per specialization or may submit any other relevant topic in coordination with the supervisor)

Unit Contents Unit I

Strategies in organic synthesis Oxidations: Swern, Prevost and Woodward oxidations. Reductions: Birch reduction, Reduction with LiAlH4, NaBH4, BH3, AlH3, and tri-n-butyl tin hydride. Organo- metallic reagents: Use of Organo lithium, Silicon and boron reagents in Organic synthesis. Modern Organic Synthetic Reactions: Aza-Cope and Aza-Wittig reactions, Baylis-Hillman reaction, BINAL and BINAP assisted reactions, Buchwald-Hartwig coupling, Click reaction, Grubb’s catalyst and RCM olefin metathesis, Heck reaction, Julia- Lythgoeolefination, Mukayama aldol reaction, Mitsunobu reaction, McMurray reaction, Peterson’s stereoselective olefination, Suziki, coupling.

Unit II Chemical kinetics and photochemistry Chemical kinetics: Structure-Reactivity relationships-Linear free energy relationships. Hammett equation–The substituent constant and exalted sigma values. The Reaction constant and the importance of rho value in arriving at the mechanism of reactions. Deviations from Hammett correlations. Taft equation and Taft four parameter equation. The Swain–Scott equation-Correlations for nucleophillic reactions. The Edward equation. The reactivity-selectivity principle and the iso selectivty rule. The intrinsic barrier and Hammond’s postulate.

Photochemistry: Formation of excimers and exciplexes –Quantum yields. Electronically excited states-singlet and triplet states. Uni molecular decay of the excited state-internal conversion, inter system crossing, fluorescence and phosphorescence. Principles of energy transfer-photosensitization. Flash photolysis and it’s applications.

Organic photochemistry: Properties of and states. Photochemistry of alkenes: Cis-trans isomerisation, di-methane rearrangement. Photochemistry of carbonyl compounds: i) Norrish type-I reactions. Photoreduction and photooxidation. ii) Norrish type-II reactions. Addition of carbonyl to carbon-carbon multiple bonds (Paterno-Buchi) reaction.Barton reaction.

Singlet oxygen –photo oxidation and reactions with C=C compounds. Ru (bpy)32+ as sensitizer

for photo redox reactions. Photochemical cleavage of water.

Unit III Principles of spectroscopy IR Spectroscopy: Introduction, Principles, Characteristic vibrational frequencies of functional groups, Fermi resonance, Effect of hydrogen bonding on vibrational frequencies. Electronic spectroscopy: Introduction, Principles and Wood -Ward Fisher rules. NMR Spectroscopy (HNMR): Introduction, Principles, factors effecting the chemical shifts, spin- spin coupling, first order spectra Mass Spectrometry: Introduction, Principles, use of isotopic peaks, salient feature of fragmentation of organic compounds, McLafferty rearrangements, retro Diels-Alder fragmentation and ortho effects. Atomic Absorption Spectroscopy (AAS): Principles of AAS–flame AAS and furnace AAS, sensitivity and detection limits in AAS, interferences –chemical and spectral, evaluation methods in AAS and applications in qualitative and quantitative analysis. Atomic Emission Spectroscopy (AES): Principles of AES, Instrumentation, evaluation methods and application in quantitative analysis

Unit IV Heterogeneous catalysts Heterogeneous catalysis: Broad categories of catalysts–metals, bimetals, semiconductors, insulators, zeolites, oxides and nano materials. Preparation of metal catalysts: Supported metal catalysts and non metallic catalysts. Characterization of catalysts: Surface area by BET method. Determination of pore volume and pore

10 size distribution by BJH method. Pore size and specificity of catalysts. Surface acidity of catalyst & determination of surface acidity by indicator method, IR spectroscopic method and TPD method. Steps in heterogeneous catalyzed reactions: Catalytic activity–the determining factors. Structure sensitive and structure in sensitive catalysts. Mechanism of surface-catalyzed reactions. The Langmuir -Hinshelwood and the Eley-Rideal mechanisms. Rate constants and activation energies of surface reactions. Introduction to Phase-transfer catalysis (PTC): Principles of phase-transfercatalysis.PTC classification. Role of water in phase-transfer catalyzed reactions. Factors influencing the rate of PTC reactions. Inverse phase transfer catalysis.

Unit V Functional polymers Smart materials–uses of smart materials in sensing devices and communication networks. Conducting polymers: Electrically conducting polymers and their uses (polyanilines, poly-pyrrole, poly-acetylene and poly-thiophene). Photo conductive polymers. Liquid crystal polymers–smectic, nematic and cholesteric structures. Ionic exchange polymers: Cationic and anionic exchange polymers and their uses. Eco-friendly polymers. Poly lactide from corn derived dextrose, PHB etc. Membrane separation. Filtration–micro, ultra and nano-filtration. Separation of gases–permeability selectivity and gas permeability of representative polymers. Liquid separation–dialysis, electro osmosis and reverse osmosis. Fire retarding polymers, photonic polymers. Inter penetrating networks (IPN), polymers in photo lithography, Polymers in biomedical applications–artificial organs and controlled drug delivery. Emerging polymers: PTTC-(poly tri-methylene tetra phthalate), Nylon 4,6 (Stanyl)–their structures, properties and uses.

Unit VI Electrochemistry Electrode-electrolyte interface: The electrical double layer. The Helmholtz-Perrin parallel-plate model, the Gouy-Chapman diffuse-charge model and the Stern model. Corrosion: Electrochemical mechanism of corrosion. Types of corrosion, various methods of corrosion control. D.C Polarography : Dropping mercury electrode-polarography Instrumentation-polarogram. Types of limiting Currents: Adsorption, Diffusion, Kinetic. Ilkovic equation and its consequences. Applications of polarography. Determination of stability constant of complex. Cyclic Voltammetry: Principle, instrumentation, reversible and irreversible cyclic voltammograms. Applications. Cyclic voltammetric study of insecticide parathion. Electro-Organic synthesis: Electro chemical reduction of carboxylic acids, Electrochemical reduction of nitro compounds. Anodic oxidation of metals: Characteristics of anodic oxide films. Instrumentation –break down voltage. Industrial applications of anodic oxide films.

Unit VII Material science and molecular modeling Preparative methods of inorganic solids: Ceramic, coprecipitation, sol-gel, chemical vapor transport. Characterization techniques of inorganic solids: X-ray powder diffraction (XRD),transmission electron microscopy (TEM) and X-ray photoelectron spectroscopy (XPES). Composites: Classification, fiber reinforced composites-influence of fiber length. Nanomaterials: preparation by sol-gel and hydrothermal methods, characterization by powder XRD- Scherer’s equation and general applications. QSAR parameters–Physiochemical parameters- Lipophilicity -Electronic parameters, Steric parameters, effect of electronic and steric parameters on lipophilicity. Hansch analysis, significance of slopes and intercepts in Hansch analysis. QSAR- 2D, 3D.

11

,

Case study–on Pyranenamine. Achievements of QSAR–Forecasting biological activity, selection of proper substituents, bio-isosterism, drug receptor interactions and pharmacokinetic information– Introduction to data base similarity Search–Alignment; Alignment methods, Pair-wise alignment; Multiple Sequence Alignment–Homology Modeling–Energy minimization methods–Active site Identification –Virtual Screening – Small molecule Building – Docking Algorithms –Docking Analysis

Unit VIII Bonding metal complexes, electron absorption spectroscopy Molecular Orbital Theory of Metal Complexes: Symmetry Classification of Metal and Ligand Orbitals in Cubic and Non-Cubic Environments: Octahedral, Tetrahedral, Square Planar, Square Pyramidal, Trigonal Bipyramidal Geometries–Concept of Ligand Group Orbitals–Construction of Molecular Orbital Energy Level Diagrams for Octahedral, Tetrahedral and Square Planar Metal Complexes with Sigma (σ) and Pi (π) Bonding Contribution from the Ligands

Unit IX IR, RAMAN, NMR and ESR

IR and Raman: Symmetry Based Selection Rules of Infrared and Raman – Symmetry Requirements for Overtone, Binary and Ternary Combination Bands -Fermi Resonance . Application of IR spectroscopy in the structural elucidation of inorganic compounds and metal complexes- Aquo, sulfato, carbonato, nitro and carbonyl metal complexes. Multinuclear NMR: Characteristic Nuclear Properties of 1H, 13C,19F,31P and 15N -Reference standards-Ranges of Chemical Shifts –Use of Chemical Shifts and Coupling Constants for the structure determination of simple inorganic and Coordination Compounds containing one or more

of1H, 13C,19F, 31P and 15N nuclei. Examples; (1)1H-NMR: Pt HCl (PEt3)2, Pt (NH3)3(CH3)3,

BH4-, [h7C7H7Mo(CO)3]+

B2H6; (2)19F-NMR: PF5, BF4-, SF4; (3)31P-NMR: H3PO2, H3PO3, H3PO4, [Rh

(PPh3)3Cl3], [Mo(CO)3(PPh3)3], [Rh (PPh3)3Cl] , ATP. (4)13C-NMR:[h4C8H8 Ru(CO)3], Fe(CO)5, Fe2(CO)9, Fe3(CO)12, [13C15N Co(DH)2Pyridine].

ESR of Metal Complexes: Principle-Selection Rules –. g value and its significance, Interpretation of g in cubic , axial and rhombo-hedral geometries. Factors affecting g values. Calculation of g values with simple examples. Intensities of ‘g║ and g┴ peaks . Evidence for Metal-Ligand Bond Covalency-Cu(II)-Bis –Salicylaldimine. Co3(CO)9Se, [(NH3)5CoO2Co

(NH3)5]5+, Cu(II)-diethyldithiophosphinate, Vanadyl dithio phosphinate, Copper(II) tetraphenyl porphyrin, Co(II)-phthalocyanine, K2[IrCl6].

Unit X Super molecules and organo metallic catalysts Supra molecular chemistry Host–Guest chemistry :Definition and different types of host and guests with examples–types of no covalent interactions–binding constants of host guest complex and thermo dynamics involved in it–designing principles of host. Cation guest binding–binding between metal cations and macrocycles–chelate and cryptate effects–relationship between cavity size of host and cation radius and stability of resultant complexes–binding of macro cycles having secondary binding sites–Anion guest binding–different hosts for anionic guests capable of binding through electrostatic interactions, hydrogen bonds, lewis acidic hosts–enhancement of binding strength housing more than non covalent interactions –Neutral guest binding–binding of neutral guest using hydrogen bonding, π-π stacking, hydrophobic effect and charge transfer interactions–simultaneous binding of cation and anion guests–cascade approach, individual binding sites and zwitterions approach –present and future applications–phase transfer agents–separation of mixtures–molecular sensors–switches and molecular machinery. Catalytic role of Organometallic Compounds: Oxidative addition and Reductive Elimination: Stereochemistry and Mechanism of Oxidative Addition – Insertion Reactions – Hydrogenation of Olefins–Transfer Hydrogenation–Hydroxylation of Olefins–Isomerisation of Olefins–Ziegler– Natta Polymerization of Olefins –Oligomerization of Butadiene . Alkene Metathesis. Oxidation of Olefins to Carbonyl Compounds–Oxidation of Hydrocarbons to Alcohols and Acids –Oxidation of Aldehydes.

12 Reactions of Carbonmonoxide and Hydrogen: Hydroformylation –Carbonylation–Syngas-Watergas shift Reaction (WGS)–Reactions of Syngas. Applications of Metal Clusters in Catalysis:

Hydroformylation of Ethyleneusing [HRu3(CO)11]– ,Hydrogenation of Olefins. Use of [Fe6C(CO)16] as a model for Fischer–Tropsch process.

Unit XI Bio inorganic chemistry Role of metal ions in biology–four basic principles in the biological selection of elements–brief survey of metal ions in biological system–effect of metal ion concentration and physiological effect. Cobalt- enzymes: chemistry, biochemistry and medicinal aspects of vit B12–structure of vit-B12 various forms–Base‘On’and Base‘Off’ and His‘On’or His‘Off’forms–complete and incomplete corrinoids –comparison of two biologically active forms of vitB12–catalyzed reactions of vit-B12 using coenzyme Bandmethyl cobalamin–biomethylation, methyl transfer to mercury and arsenic–vit -B12 as drug transport vehicle–biochemistry–functions of vitB12, symptoms and causes of vit B12 deficiency, absorption and storage of vit B12– historical events in the discovery of vit B12. Nickel-enzymes: Urease–active site–mechanism of degradation of urea to carbon dioxide and ammonia. Copper-enzymes: Substrate specific antioxidants –Cu, Zn superoxide dismutase –structure and catalytic mechanism. Zinc-enzymes: Role of zinc in catalytic activities of carbonichydrase, carboxy peptidase and alkaline phosphate. VitB6: Various forms–mechanism of catalysed reactions Platinum complexes in cancer therapy: Discovery, applications and structure effect Relationships. Cis platin(cis Pt(NH3)2Cl2) mode of action. Drug resistance and DNA repair mechanism. Physical effects of metal complex: DNA binding, unwinding, shortening and bending of the double helix. Biological consequences of platinum –DNA binding. Transition metal complexes as donor acceptor pairs. Non classical platinum antitumor+agents.

Unit XII NMR Spectroscopy 13C NMR (CMR) Spectroscopy: Principles involved and different types of CMR spectra, Chemical shifts and coupling in CMR. Applications of CMR spectroscopy to structure determination,

stereochemistry, reaction mechanisms and dynamic processes inorganic molecules.13CNMR spectral editing techniques. Principles and applications of APT, INEPT and DEPT techniques.

22D-NMR Spectroscopy: Principles and applications of the following 2D-NMR experiments. i) HOMO and Hetero nuclear J resolved spectroscopy ii) HOMOCOSY and TOCSY

iii) HETERO COSY , HMQC and HMBC iv) NOESY v) INADEQUATE

Unit XIII Natural product chemistry

IR, UV, 1H, 13C, 2D-NMR and mass spectral studies of the following classes of Natural Products: i) Coumarins ii)Flavones iii)Isoflavones iv) Flavanones v) monoterpenes vi) Quinoline and isoquinoline alkaloids (cusparine and papaverine) Structure elucidation, synthesis andstereochemistry of the following. i) Taxol ii) Vincaleucoblastine iii) Reserpine iv) Rotenone.

Unit XIV Modern concept of organic chemistry and green chemistry New Techniques and concepts inorganic synthesis. i) Combinatorial synthesis ii) Phase transfer catalysis iii) Tandem synthesis iv) Mosher’s method for configuration determination v) Baldwin rules vi) Kahne’s glycosidation vii) Methods of oligo-nucleotide synthesis. Green Chemistry: Introduction, principles of green chemistry, Different approaches to green synthesis: Microwave and Ultrasound assisted organic synthesis, Solid phase and aqueous phase organic synthesis.

Unit XV Synthetic strategies and asymmetric synthesis Design of Organic synthesis: Terminology, Retro synthesis, FGI, disconnection, on synthetic equivalent, protects groups, chemo selectivity, region selectivity and stereo selectivity. Linear and convergent strategies, Use of disconnection approach in the synthesis of multistriatin, Warfar in and α-

13

RECOMMENDED STUDY MATERIALS

bisabolene. Asymmetric Synthesis: Terminology, concepts of prochirality, enantio selectivity and ia stereo selectivity. Methods for determination of enantiomer purity: Polarimeter, H-NMR and HPLC methods.

i)Asymmetric hydrogenation using chiral Wilkins on biphosphine and Noyori catalysts; approaches to L-DOPA and α-amino acids.

ii) Asymmetric aldol reaction and asymmetric Diels- Alder reaction.

iii) Chiron approach to stereo selective synthesis of (-) PGE2 and (-) shikimic acid.

Unit Title of the Books Unit I 1. Some modern methods of organic synthesis by W Carruthers

2. Guidebook to organic synthesis, by R K Meckie, D M Smith & R A Atken 3. Organic synthesis by O House 4. Organic synthesis by Michael B Smith 5. Reagents for organic synthesis, by Fieser & Fieser, Vol 1-11(1984) 6. Organic synthesis by Robert E Ireland 7. Organic Synthesis -The disconnection approach by S Warren 8. Organic Synthesis by C Willis and M Willis 9. Handbook of reagents for organic synthesis by Reich and Rigby, Vo I, IV 10. Problems on organic synthesis by Stuart Warren 11. Total synthesis of natural products: the Chiron approach by S.Hanessian 12. Organic chemistry Claydon and others 2005 13. Name Reactions by Jie Jack Li 14. Reagents in Organic synthesis by B.P.Mundy and others. 15. Tandem Organic Reactions by Tse-Lok Ho

Unit II 1. Chemical Kinetics, K. J. Laidler, McGraw Hill 2. Kinetics and Mechanism, A. A.Frost & R. G. Pearson, John Wiley& sons 3. Kinetics and Mechanism of Chemical Transformations, J. Rajaraman &J.

Kuriacose, McMillan 4. Chemical Kinetics and Reaction Mechanisms, J. H. Espenson, McGraw Hill 5. Physical Organic Chemistry, N. S. Isaacs, ELBS 6. The Physical basis of Organic Chemistry, Howard Maskill, Oxford University Press 7. Molecular Photochemistry, N. J. Turro, W. A. Benzamin 8. Fundamentals of Photochemistry, Rohatgi-Mukherjee, Wiley Eastern 9. Essentials of Molecular Photochemistry, A. Gilbert & J. Baggott, Blackwell Science 10. Introduction to Molecular Photochemistry, C. H. J. Wells, Chapman and Hall

Unit III 1. Fundamentals of Molecular Spectroscopy, Banwell and McCash. 2. Introduction to Molecular Spectroscopy, G.M. Barrow 3. Absorption Spectroscopy of Organic Compounds, J.R. Dyer 4. Biochemistry: Hames and Hooper. 5. Spectroscopic identification of organic compounds by R.M.Silverstein. G.C. Bassler and T.E. Morrill 6. NMR-A multinuclear introduction by William Kemp 7. Organic Spectroscopy by William Kemp 8. Spectroscopic methods in Organic chemistry byDH Williams andI Fleming 9. Modern NMR techniques for chemistry research by Andrew B Derome 10. NMR in chemistry -A multinuclear introduction by William Kemp 11. Spectroscopic identification of organic compounds by P S Kalsi 13. Introduction to organic spectroscopy by Pavia

14 14. Carbon-13 NMR for organic chemists by GC Levy and O L Nelson 15. Principles of Instrumental Analysis, Skoog, Holler and Nieman. 16. Instrumental Techniques for Analytical Chemistry,Frank Settle. 17. Principles of Analytical Chemistry,M. Valcarcel.

Unit IV 1. Principles of Heterogeneous Catalysis in practice, G. C. Bond, Oxford Publishing

2. Heterogeneous Catalysis, C. Satterfield, McGraw Hill 3. Catalysis, Principles and applications, edited by B.Vishwanathan, S.Sivasanker & A.V.Rama

Swamy, Narosa Publishing House 4. Catalysis, J. C. Kuriacose, Macmillan 5. PhaseTransferCatalysis,Fundamentals ,Applications and Industrial perspective, C.M.Stark, C.

Liotta & M. Halpern, Academic Press 6. Phase Transfer Catalysis, E. V. Dehmlow & S. S. Dehmlow, Verlag Chemie, Weinheim 7. Phase Transfer Catalysis in Organic synthesis, W. P. Weber & G. W. Gokel, Springer

Unit V 1. Textbook of Polymer Science, F. W. Billmeyer Jr, John Wiley & sons 2. Polymer Science, V. R. Gowarikar, N. V. Viswanathan &J. Sreedhar, Wiley Eastern 3. Contemporary Polymer Chemistry, H. R. Alcock & F. W. Lambe, Prentice Hall 4. Physics and Chemistry of Polymers, J. M. G. Cowie, Blackie

Academic and professional 5. Ploymer Chemistry, B. Vollmert 6. Physical Chemistry of Polymers, A. Tagers, Mir Publishers 7. Introduction to polymer Chemistry, By Charles E Carraher Jr ( Taylor-Frncis)

Unit VI 1. Modern Electrochemistry 2A & 2B, J. O. M. Bockris & A. K. N. Reddy, Plenum publishers

2. Introduction to Electrochemistry, S. Glasstone 3. Industrial Electrochemistry, D. Pletcher, Chapman & Hall 4. Fundamental principles of Modern Electroplating, Lowenheim, John Wiley 5. Principles of Polarography, Heyrovsky. 6. Principles of Polarography, Kapoor. 7. Modern Electroanalytical methods, edited by C.Charlot, Elsevier Company. 8. Principles of Instyrumental analysis, Skoog, Holler andNieman, Harcourt Asia PTE Ltd. 9. Analytical Chemistry-AnIntroduction, Skoog, West, Holler and Crouch, Saunders College

Publishing. 10. Prinicples of Instrumental Analysis, Skoog and Leary, Saunders College Publishing.

Unit VII 1. Solid state and its applications by A.R. West.

2. New directions in solid state chemistry, J. Gopalakrishnan and C.N. R. Rao. 3. Principles of the solid state by HV Keer. 4 .Burger’s medicinal chemistry and drug discovery.By Manfred E. Wolf.

5. Introduction to Medicinal chemistry. ByPatrick.

6. Introduction to drug design. By Silverman

7. Comprehensive medicinal chemistry. Vol 1-5 By Hanzsch.

8. Principles of medicinal chemistry. By William Foye

9. Biochemical approach to medicinal chemistry. By Thomas Nogrady.

10. PharmaceuticalChemistry and Drug synthesis By Roth and Kleeman

11. Drug design By E.J. Arienes

12. Jenkin’s quantitative pharmaceutical chemistryBy Knevel and Dryden

15

13. Recent advances in Bioinformatics By I. A. Khan and A Khanum

14. Computational chemistry By GH. Grant and WG. Richards

15. Molecular modelling By Hans Dieter Holtje and Gerd Folkers

16. Molecular modelling By Leach

17. Computational Chemistry by Jenson

18. Bio Informatics by Rastogi

19. The Science and practice of Pharmacy –Vol I and Vol II by Remington

Unit VIII 1. Symmetry and Spectroscopy of Molecules, K. Veera Reddy, Second Edition,New Age International (P) Limited Publishers (2009)

2. Chemical Applications of Group Theory, F. A. Cotton, 3rdedition, WileyNY (1990) 3. Symmetry and Group Theory In Chemistry, Mark Ladd, Harwood Publishers, London (2000)

4. Symmetry Through the Eyes of a Chemist,I. Hargittai and M. Hargittai, 2ndEdition, Plenum Press, NY (1995)

5. Molecular Symmetry and Group Theory, Robert L. Carter, John Wiley& Sons (1998) 6. Group Theory for Chemists,G. Davidson, Macmillan Physical Science Series (1991) 7. Molecular Symmetry, Schoenland 8. Electronic Spectroscopy, A. B. P. Lever

Unit IX 1. Introduction to Ligand fields,B. N. FiggisInfrared and Raman Spectroscopy of Inorganic and

Coordination Compounds, K. Nakamoto 2 .Infrared spectroscopy of Inorganic Compound, Bellamy

Unit X 1. Physical Methods in Chemistry, R. S. Drago, W.B. Saunders Co., 1977.

2. Chemical Structure and Bonding,R.L. Decock and H.B. Gray. 3. Physical Methods for Chemists,Russell S. Drago Second edition, Saunders ,CollegePublishing, 1992. 4. Comprehensive Coordination Chemistry, Vol 6. 5. Modern Coordination Chemistry, Lewis and Wilkins. 6. Organometallics-A Concise Introduction, Ch.Eischeinbroich and Salzer-VCH 7. Organotransition Metal Chemistry Fundamental Concepts and Applications, John AkioYamamato, Wiley & Sons. 8. Homogeneous Catalysis by Metal Complexes, M M Taqui Khan and A E Martel 9. Applied Homogenous Catalysis with Organo Metallic Compounds Vol I & II, Boy Cornills and W A

Herrmann–VCH 10. Homogenous catalysis, G W Parshall, John Wiley & Sons, New York 11.Inorganic elements in the Chemistry of life, Wolfgang Kaim & Brigette

Schwederdki.

Unit XI 1. Bio inorganic Chemistry, Bertini, Lippard and Valentine, University Science Books, California USA, 1994

2. Principles Bioinorganic Chemistry., S J Lippard and Berg University Science Books, California USA, 1994

3. Biological Chemistry of Elements, J. J.R. Franstodasilva and R.J.P. Williams, aoxford. University Press 1991 4. Metal ions in Biological Systems ( series) Ed.H. Sigel Marcel Dekkar, New York 5. Inorganic Biochemistry, J.A. Cowan, VCH publishers 1993 6. Advances in Inorganic Biochemistry, edited by by G.L. Eichorn & Marzilli

16 7. Bioinorganic Chemistry, Vol-I edited by G. L. Eichorn

Unit XII 1. Spectroscopic identification of organic compounds by RM Silverstein, G C Bassler andT B

Morrill 2. Organic Spectroscopy by William Kemp 3. Spectroscopic methods in Organic chemistry byDH Williams andI Fleming 4. Modern NMR techniques for chemistry research by Andrew B Derome 5. NMR in chemistry -A multinuclear introduction by William Kemp 6. Spectroscopic identification of organic compounds by P S Kalsi 7. Introduction to organic spectroscopy by Pavia 8. Carbon-13 NMR for organic chemists by GC Levy and O L Nelson

Unit XIII 1. Textbook of organic chemistry, Vol II by I L Finar

2. Chemistry of natural products, Vol 12, by Atta-Ur-Rahman 3. An introduction to the chemistry of terpenoids and steroidsby William templeton 4. Systematic identification of flavonoid compounds by Mabry & Markham 5. Steroids by Fieser andFieser 6. Alkaloids by Manske 7. Alkaloids by Bentley 8. The chemistry of terpenes by A Pinder 9. The terpenes by Simenson 10. Terpenoids by Mayo 11. Alkaloids by Pelletier 12. Total synthesis of Natural Products by Apsimon Vol 1-5 13. Biosynthesis by Geismann 14. Principles of organic synthesis 3rdEd.R O C Norman and J M Coxen 15. One and two dimensional nmr spectroscopy by Atta Ur Rahman 16. Classics in total synthesis K C Nicolaou and E J Sorenson

Unit XIV 1. Some modern methods of organic synthesis by W Carruthers

2. Guidebook to organic synthesis, by R K Meckie, D M Smith & R A Atken 3. Organic synthesis by O House 4. Organic synthesis by Michael B Smith 5. Reagents for organic synthesis, by Fieser & Fieser, Vol 1-11(1984) 6. Organic synthesis by Robert E Ireland 7. Organic Synthesis -The disconnection approach by S Warren 8. Organic Synthesis by C Willis and M Willis 9. Handbook of reagents for organic synthesis by Reich and Rigby, Vo I, IV 10. Problems on organic synthesis by Stuart Warren

Unit XV

1. Stereochemistry: Conformation & Mechanism by P S Kalsi 2. Stereochemistry of Carbon compounds by Ernest L Eliel 3 .Stereo selectivity in organic synthesis by R S Ward. 4. Asymmetric synthesis by Nogradi 5. Asymmetric organic reactions by it) Morrison and HS Moscher 6. Stereo differentiating reactions by Izumi 7. Some modern methods of organic synthesis by W Carruthers 8. Guidebookto organic synthesis, by R K Meckie, D M Smith & R A Atken 9. Organic synthesis by Michael B Smith 10. Organic Synthesisby C. Willis & M. Willis 11. Total Synthesis of natural products: the Chiron approach by S. Hanessian 12. Organic Synthesis-The disconnection approach by S. Warren 13. Problems on Organic Synthesisby Stuart Warren 14. Organic Chemistry by Claydon and others.

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C. MATHEMATICS (Candidate will have the option to select any five units from the following list of units as per specialization or may submit any other relevant topic in coordination with the supervisor)

Unit Contents Unit I Real analysis

Elements of set theory: Countable and uncountable sets, Infinite sets, Cardinal numbers and their arithmetic, Schroeder-Bernstein theorem, Cantor's theorem and the continuum hypothesis, Poset, Axiom of choice, Housdorff maximality principle, Tukey's theorem, Zorn's lemma, well ordering theorem. Sequence and series of real numbers: Sequence, Limit of a sequence, Convergence of sequence, limit superior, limit inferior of a sequence of real numbers, Cauchy sequence, Series, Convergence of Series, tests for Convergence of Series. Riemann Integral: Darboux's upper and lower sums, lower and upper integrals, Riemann integral criterion for Riemann integrability, Properties of integral functions, Fundamental theorem of calculus, the integral as a limit of sum. Improper Integrals: Improper integrals, types of improper integrals, Convergence of improper integrals, test integrals and some tests for convergence. Gamma and Beta functions.

Unit II Complex analysis Complex functions as mappings, Analytic function, Bilinear transformation, Conformal mappings. Power series representation of Analytic functions, Radius of convergence, Cauchy's estimate, Zero's of analytic functions, Integration in complex plane. Fundamental theorem of algebra, Maximum modulus theorem. Singularities, Classification, Poles and essential singularities, Singular point, Laurent series, Residues and evaluation of integrals. Entire functions, Weierstrass theorem.·

Unit III Algebra Groups, subgroups, normal subgroups, quotient groups, homomorphisms, cyclic groups, permutation groups, Cayley's theorem, class equations, Sylow theorems. Rings, ideals, prime and maximal ideals, quotient rings, unique factorization domain, principal ideal domain, Euclidean domain. Polynomial rings and irreducibility criteria. Fields, finite fields, field extensions, Galois Theory.

Unit IV Linear algebra Vector Spaces, Subspaces, Linear dependence and Linear independence of Vectors, System of linear equations, Basis and Dimension of a Vector Space, Quotient Space. Linear transformations, Range and Null Space of a linear transformation, Trace of a matrix, Eigen values and Eigen vectors, The Cayley-Hamilton theorem, Minimal polynomial. Modules, Submodules, Free modules, Faithful modules, Direct sum of modules. Local rings and Modules, Jordan Canonical forms.

Unit V Ordinary and partial differential equations Second order linear equations: Fundamental solution of the homogeneous equation, linear independence, reduction of order, linear equations with constant coefficients, method of undetermined coefficients, method of variation of parameters. System of first order equations: solution of linear system, basic theory of system of first order linear equations, linear homogeneous system, fundamental matrices, non homogeneous linear system. Elementary Partial Differential Equations: Definitions, equations solvable by direct integration, nonlinear equations of first order, Charpits method. Single first order PDEs: Semilinear and quasilinear equations, characteristics Cauchy problem, general solutions. Classification of second order PDEs.

Unit VI Advance topics in differential equations Uniqueness and Lipschitz and conditions for Ordinary Differential Equations – Boundary Value

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Problems, Linear Ordinary differential systems some general properties. Method of steps, Lipschitz conditions and Uniqueness. Existence theory: Ordinary differential systems, systems with bounded delays, notation and Uniqueness. existence Linear delay differential systems, Superposition, constant coefficients, variation of parameters. Stability: Definition and examples Liapunov method for uniform stability, Asymptotic stability linear and quasilinear ordinary differential systems. Autonomous Ordinary differential systems, trajectories and critical points, linear systems of second order critical points of quasilinear systems of second order.

Unit VII Special function and integral transform Laplace Transforms: Definition, notation, sufficient condition for existence, properties of L.T., Initial value and final value theorems. Methods of finding L.T., Defmition of Inverse Laplace transform, uniqueness and properties, Convolution theorem. Methods of finding inverse L. T., Applications of L.T. to LDE and PDE. Fourier Transforms: The Fourier Integral, complex form of Fourier Integrals and Fourier Integral theorem; Fourier transforms; Fourier Cosine and Sine Transforms, Finite Fourier transforms, Convolution theorem, Parsval’s Identity. Linear Boundary value problems: Introduction, wave equation, heat equation and Laplace’s equation in Cartesian, Cylindrical and Spherical co- ordinates. Principle of superposition, series solutions, Fourier Series, Solution of Linear boundary value problem by separation of variables, types of initial value problems and general solution of partial differential equations. Sturm-Liouville problems Special function: Bessel functions : recurrence relations for the Bessel co -efficients – Series expansion for Bessel co-efficients –Integral expression for the Bessel co-efficients. The additions formula for the Bessel co-efficients.

Unit VIII Discrete mathematics and graph theory Statements & Notation – Connectives - Well formed formulas – Duality law – Functionally complete sets of connectives – Normal forms and principal normal forms. Theory of Inference for the statement calculus – Rule of inference – Automatic theorem proving – Predicate calculus. Representation of Discrete Structures – Relations and ordering – Functions – Composition of functions and inverse functions – Recursive functions, sets and predicates.Lattices and Boolean algebra – Lattices as a partially ordered sets – Some properties of lattices, lattices as algebraic systems – Sublattices – Direct product and Homomorphism – special Lattices – Boolean algebra – Boolean functions, - Representation and minimization of Boolean functions. Graphs – Isomorphism – Sub graphs – Euler Graphs – Hamiltonian paths and Circuits – Travelling salesman problem – Trees – Properties of trees – Spanning trees – Minimal spanning trees – Kruzkal’s algorithm – Premis algorithm – Dijkstra’s algorithm. Cut-sets and cut-vertices – Planar graph duality in planner graphs – Matrix representation of graphs – incidence matrix – Adjacent matrix path matrix – Circuit matrix – Cut set matrix – Transitive closur or a graph – Warshall’s algorithm.

Unit IX Fluid mechanics Kinematics of fluids in motion: Real fluid and ideal fluids-Velocity of fluid at a point-Streamlines and pathlines-Steady flow and unsteady flow, velocity potential, velocity vector, local and partical of fluid, conditions at a rigid boundary, general analysis of fluid motion. Equations of motion of a fluid: Pressure at a point in a fluid at rest-Pressure at a point in a moving fluid- Conditions at boundary of two in viscid in compressive fluids- Euler’s equation of motion-Bernoulli’s equation. Three dimensional flows: Sources–Sinks–Doublets -Images in a rigid infinite plane-Images in solid spheres- Axisymmetric flows –Stokes stream function for axisymmetrical irrotational motions. Two dimensional flows: Meaning of two dimensional flow-Use of cylindrical polarcoordinates-stream function, complex potential for two dimensional irrotational incompresive flow - Complex velocity potentials for standard two dimensional flow- Uniform streamline sources and line sinks- Line doublets line vortices.

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Unit X Mathematical modeling

Mathematical Modelling Through differential equations, Linear Growth and Decay Models, Non-Linear Growth and Decay Models, Compartment Models, Mathematical Modelling in Dynamics Through Ordinary Differential Equations of First Order, Mathematical Modelling of Geometrical Problems Through Ordinary Differential Equations of First Order. Mathematical Modelling in Population Dynamics, Mathematical Modelling of Epidemics Through Systems of Ordinary Differential Equations of First Order, Compartment Models Through Systems of Ordinary Differential Equations, Mathematical Modelling in Economics through Systems of Ordinary Differential Equations of First Order, Mathematical Models in Medicine ,Arms Race, Battles, and International Trade in Terms of Systems of Ordinary Differential Equations, Mathematical Modelling in Dynamics Through Systems of Ordinary Differential Equations of First Order. Mathematical Modelling of Planetary Motions, Mathematical Modelling of Circular Motion and Motion of Satellites, Mathematical Modelling through Linear Differential Equations of Second Order, Miscellaneous Mathematical Models through Ordinary Differential Equations of Second Order. The Need of Mathematical Modelling through Difference Equations: Some Simple Models, Basic Theory of Linear Difference Equations with Constant Coefficients, Mathematical Modelling Through Difference Equations in Economics and Finance, Mathematical Modelling Through Difference equations in Population Dynamics and Genetics, Mathematical Modelling Through Difference Equations in Probability Theory, Miscellaneous Examples of Mathematical Modelling Through Difference Equations.

Unit XI Operational research Simplex Method: introduction–Some more definitions and notations–Computational procedure of simplex method–Simple way for simplex method computations–Artificial variable techniques. Disadvantages of big-M-method over two-phase method–What is degeneracy problem. Special cases: Alternative solutions, unbounded solutions and non-existing solutions Dual Simplex method: Introduction, Computational procedure of dual simplex method – Illustrative examples–Advantage of dual simplex method over simplex method–Difference between simplex and dual simplex methods. Transportation problems: introduction–Mathematical formulation–Matrix formation, transportation problem– Feasible solution, basic feasible solution and optimum solution–Tabular representation–Special structure of transportation problem–Loops in transportation table and their problems–Moving towards optimality Transportation algorithm for minimization problem–Degeneracy in transportation problems–Unbalanced transportation problems.

Assignment models: Introduction – Mathematical formulation of assignment problem – Fundamental theorems – Hungarian method for assignment problem – More illustrative examples – Unbalanced assignmentproblem–Variationsintheassignmentproblem–Variationsintheassignmentproblem - Sensitivity in assignment problems–The traveling sales man (Routing) Problem. Job sequencing: Introduction–Terminology and notations–Principal assumptions–Solution of sequencing problem–Processing jobs through machines.

Unit XII Applied numerical

High Speed Computation Introduction, computer Arithmetic, errors in numerical Techniques, machine computation and computer software. Transcendental and Polynomial Equations : Introduction, Rate of Convergence, General Iteration methods, Birge – Vieta, Baristow’s, Muller, complex roots, system of non – linear equations by Newton’s method. System of Linear Algebraic Equations and Eigen value Problems: Introduction, Direct Methods– Consistency, Rank of a matrix Gaussian elimination, LU decomposition (Crout’s algorithm), Cholesky algorithm, Tri-diagonal system of equations and Banded system of equations. Eigen values and Eigen vectors: Eigen values and Eigenvectors, bounds on Eigen values, Jacobi’s

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Method for Symmetric Matrices, Given Method for Symmetric Matrices, Householder’s Method for Symmetric Matrices, largest Eigen value by power method. Interpolation and Approximation: Introduction, Lagrange and Newton Interpolations, Interpolating polynomials piece wise polynomial interpolation, Spline’s interpolation formula, Hermite Interpolation, Bivariate Interpolation. Numerical integration: Newton’s cotes formula, Simpson’s rules, Weddle’s rule, Gaussian Ordinary Differential Equations: Boundary Value Problems: Initial Value Problem and boundary value problem, Runge–Kutta’s Method, predictor–correct or formulae, shooting method for BVP.

Unit XIII Number theory Fermat and Mercenn's numbers: Farey series, Farey dissection of the continuum Irrational numbers-Irrationality of mN, e and Approximation Irrational numbers. HurWitz's Theorem. Representation of a number by two or four squares. A number n is the sum of two squares if and only if all prime factors of the form 4m+3 have even exponents. tn the standard term of n. every positive integral is the sum of four squares. Definition g(K) and G(K). Proof of g (4)<50, perfect numbers, An even perfect number is of the form 2n(2n+1)-1) where 2n+1-1 is prime. Continued fractions: Finite continued fractions, convergent to a continued fraction, continued fractions with positive quotients. Simple continued fractions, The representation of an irreducible rational fraction by a simple continued fraction. The continued fraction algorithm and Euclid's algorithm. The difference between the fraction and its convergence, Infinite simple continued fractions, the representation of an irrational number by an infinite continued fraction, Equivalent numbers periodic continued fractions, some special quadratic surds, and these rise of Fibonacci and Lucas.

Unit XIV Classical mechanics Mechanics of a particle, Mechanics of a system of particles, constraints, Generalised coordinates, D'Alembert's principle, Lagrange's equations of motion, the forms of Lagrancge's equation for velocity dependent potential, and dissipative forces, applications of Langragian formulation, cyclic co-ordinates and generalized momentum, conservation theorems. Functionals, basic lemmain calculus of variations, Euler-Lagrange's equations, the case of several dependent variables, the minimum surface of revolutions, the problem of Brachistochrone, Isoperimetric problems, Problem of the maximum enclosed area, shape of a hanging rope. Hamilton's principle, Lagrance's equations from Hamilton’s principle,(holonomiS system) Hamilton's equations of motion from a variational principle. The principle of least action cyclic coordinates and Routh's procedure, conservation theorems and physical significance of Hamiltonian The two body central force problem: Reduction to the equivalent one body problem, the equations of motion and first intergrals, classification of orbits, the virial theorem, the differential equation for the orbit, the Kepler's problem. The kinematics of rigid body motion: The independent co-ordinates of a rigid body, orthogonal transformations, properties of transformation matrix, infinite simalrotations, the Eulerianangles, the Cayley-Kleinparameters, Euler's theorem on motion of rigid body. Angular momentum and kinetic energy of motion of a rigid body about a point, The inertiatensor and moment of inertia, Euler's equations of motion.

Unit XV Functional analysis Bounded linear transformations. B(X,Y) as a nor medlinear space. Open mapping and closed graph theorems. Uniform boundedness principle and its consequences. Hahn-Banach theorem and its application. Dual spaces with examples. Separability. Reflexive spaces. Weak convergence. Compact operators .Inner producspaces, Hilbertspaces. Orthonormalsets, Bessel’s inequality. Complete orthonormal sets and Parseval’s identity. Structure of Hilbert spaces. Projection theorem. Riesz representation theorem. Riesz-Fischer theorem. Adjoint of an operator on a Hilbert space. Reflexivity of Hilbert spaces. Self-adjoint operators. Positive projection, normal, and unitary operators

Unit XVI Boundary layer theory Some features of Viscous Flows: Real and ideal fluids, viscosity, Reynolds number, laminar and turbulent flows, asymptotic behavior at large Reynold snumbers. Fundamentals of Boundary Layer theory: Boundary layer concept, laminar boundary layer on a flat plate at zero incidences, turbulent

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boundary layer on flat plate at zero incidences, fully developed turbulent flow in a pipe, boundary layer on an air foil, separation of the boundary layer. General properties and exact solutions of the boundary layer equations for plane flows: Compatibility conditions at the wall, similar solutions of the boundary layer equations, derivation of the ordinary differential equation, boundary layers with outer flow, boundary layers without outer flow, wedge flows, flowing a convergent channel, mixing layer, moving plane, free jet, walljet, series expansion of the solutions; Blasius series, Gortler series. Asymptotic behavior of solutions downstream: Wake behind bodies, boundary layer moving wall, integral relations of the boundary layer; momentum integral equation, energy integral equation, moment of momentum integral equations. Approximate methods for solving the boundary layer equations for steady planar flows: Integral methods, Stratford’s separation criterion. Comparison of the approximate solutions with exact solutions; Retarded Stagnation point flow, Divergent channel (Diffuser), Circular cylinder flow, symmetric flow pasta Joukowsky air foil.

Unit XVII Topology Topological Spaces, bases for a topology, the order topology, the product topology on X × Y, the subspace topology, closed sets and limit points continuous functions, the product topology, the metric topology, the quotient topology. Connected spaces, connected subspaces of the real line, components and local connectedness, compact spaces, compact spaces of there alline, limit point compactness, local compactness, nets. The countability axioms, the separation axioms, normal spaces, the Urysohn Lemmas, the Urysohn Metrization Theorem, the Tietze Extension Theorem, the Tychonoff Theorem.

Unit XVIII Tensors and differential geometry Tensors: Notations and Summation Convention, Transformation Law for vectors, Cartesian tensors, Algebra of Cartesian tensors, Differentiation of Cartesian tensors, Themetric tensor, Transformation of curvilinearco-ordinates, General tensors, Contravariant, Covariant derivative of a vector, Physical components, Christoffel symbol Curve with Torsion: Tangent, Principal normal, Curvature, Binomial, Torsion, Serret-Frenet formulae, Locus of Center of curvature, Circle of curvature, torsion of a curve, Involutes, Evolutes and Bertrand curves. Envelopes and Developable Surfaces: Surfaces, Tangent plane, normal, Envelop, Edge of regression, Developable surfaces, Curvilinearco-ordinates on a surface: Fundamental Magnitude. Curve on a Surface: Principal directions and curvature, First and second curvature, Euler’s theorem, Normal curvature, Mean curvature, Umblic points, Conjugate directions and asymptotic lines, Principal directions and principal curvature, Line of curvature and evolutes of a surface. Quadric Surfaces: Central quadrics, Fundamental magnitudes, The first and second fundamental forms, Formulas of Gauss and Codazzi, The fundamental theorem of surface theory, The Gauss- Bonnet Theorem.

XIX Linear and non linear programming Linear Programming and examples, Convex Sets, Hyper plane, Open and Closed half-spaces, Feasible, Basic Feasible and Optimal Solutions, Extreme Point & graphical methods. Simplex-method, Charnes-M method, Two phase method, Determination of Optimal solutions, Unrestricted variables, Duality theory, Dual Linear Programming Problems, Fundamental properties of dual problems, Complementary Slackness, Unbounded Solution in Primal. Dual Simplex Algorithm, Sensitivity Analysis. Parametric programming, Revised Simplex method, Transportation Problems, U-V method, assignment problems, Integer Programming, Gomary’s algorithm, Branch & Bound Technique. Game Theory-Two-person, Zero-sum Games with mixed strategies, graphical solution, and solution by Linear Programming. Nonlinear Programming: Convex functions, Unconstrained problems, Kuhn-Tucker conditions for Constrained Optimization, Quadratic Programming methods due to Beale, Wolfe. Duality in

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Nonlinear Programming, Weak Duality Theorem, Wolfe’s Duality Theorem, Hanson-Huard strict converse duality theorem (without proof), Dorn’s duality theorem, strict converse duality theorem, Dorn’s Converse duality theorem (without proof), Unbounded dual theorem, theorem on no primal minimum.

XX Hydrodynamics Equation of continuity, Boundary surfaces, stream lines, Irrotational and rotational motions, Vortex lines, Euler’s Equation of motion, Bernoulli’s theorem, Impulsive actions. Motion in two-dimensions, Conjugate functions, Source, sink, doublets and their images, conformal mapping, Two-dimensional irrotational motion produced by the motion of circular cylinder in an infinite mass of liquid, Theorem of Blasius, Motion of a sphere through aliquidat rest at infinity. Liquid streaming pasta fixed sphere, Equation of motion of a sphere. Stress components in real fluid, Equilibrium equation in stress components, Transformation of stress components, Principal stress, Nature of strains, Transformation of rates of strain, Relationship between stress and rate of strain, Navier-Stokes equation of motion.

XXI Solid mechanics

Analysis of Strain–Affine transformation, Infinitesimal Affine deformations, Geometrical interpretation of the components of Strain. Strain Quadric of Cauchy, Principal Strains. Invariants. General Infinitesimal Deformation. Equation of compatibility, Finite deformation. Analysis of Stress–Stress Tensor, Equations of Equilibrium. Transformation of coordinates. Stress Quadric of Cauchy. Principal stress and Invariants. Maximum normal and shear stresses, Mohr’s circle Diagram. Equations of Elasticity–Generalized Hooke’slaw. Stress–Strain relations for a medium having one plane elastic symmetry, three orthogonal planes symmetry and for homogeneous isotropic media. Elastic-moduli for isotropic media. Equilibrium and Dynamic equations for an isotropic solids. Strain energy function and its connection with Hooke’s law. Unique solution of Boundary value problem. Derivation of Navier’s equations and Beltrami-Michal compatibility equations. Statement of problem. Extension of beams by longitudinal forces. Beam stretched by its own weight. Bending of beams by terminal couples. Torsion of a circular shaft Plane stress, Plane strain.

XXII Advanced discrete mathematics Formal Logic-Statements, Symbolic Representation of statements, duality, Tautologies and contradictions. Quantifiers, Predicates and Validity of arguments. Propositional Logic. Languages and Grammars, Finite State Machines and the irtransitiontable diagrams. Lattices: Lattices as partially ordered sets, their properties, duality, Lattices as algebraic systems, Sub lattices, Direct products, Bounded Lattices, Complete Lattices, Complemented Lattices and Distributive lattices. Cover of an elements, atoms, join and meet irreducible elements. Boolean Algebras: Boolean Algebras as lattices. Various Boolean Identities. The Switching Algebra example. Sub algebras, Direct products and Homeomorphisms. Boolean forms and their Equivalence. Min-term Boolean forms, Sum of product Canonical forms. Minimization of Boolean functions, Applications of Boolean Algebra to Switching Theory (using AND, OR & NOT gates). The Karnaugh Map method .Definition of (undirected) graph,Walk, Path, Circuit, Cycles, Degree of a vertex, Connected graphs, Complete and Bipartite graphs, Planar graphs, Euler’s formula for connected Planar graphs, Kuratowski’s Theorem (Statement only) and its uses. Colouring of graphs, Five colour theorem and statement of Four colour theorem. Trees, Cut- sets, Spanning Trees, Fundamentals Cut-sets and minimum Spanning Trees, Prim’s and Kruskal’s algorithms, Connectivity, Matrix Representation of graphs, Directed Graphs, In degree and outdegree of a vertex.

XXIII Probability models

Random events and random variables: Random events - Probability axioms - Combinatorial

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formulae-conditional probability- Bayes Theorem-Independent events- Random Variables- Distribution Function- Joint Distribution- Marginal Distribution- Conditional Distribution- Independent random variables-Functions of random variables. Parameters of the distribution: Expectation- Moments - The Che by shev Inequality – Absolute moments- Order parameters- Moments of random vectors- Regression of the first and second types. Characteristics functions: Properties of characteristic functions -Characteristic functions and moments -semi-invariants -characteristic function of the sum of the independent random variables - Determination of distribution function by the Characteristic function - Characteristic function of multidimensional random vectors- Probability generating functions. Some probability distribution: One point, two point, Binomial- Polya-Hyper geometric- Poisson (discrete) distributions- Uniform-normal gamma-Beta-Cauchy and Laplace (continuous) distributions. Limit theorems: Stochastic convergence -Bernoulli law of large numbers -Convergence of sequence of distribution functions –Levy –Cramer Theorems -deMoivre-Laplace Theorem- Poisson, Che by shev, Khintchine Weak law of large numbers -Lindberg Theorem -Lyapunov Theorem - Borel-Cantelli Lemma-Kolmogorov Inequality and Kolmogorov Strong Law of large numbers.

XXIV Magneto-hydrodynamics Basic equations –out line of basic equations of MHD including Faraday’s laws and constitutive laws. Magnetic induction equation – Lorentz force – MHD approximations. Non-dimensional numbers–velocity, temperature and magnetic field boundary conditions. Exact equations – Hartmann flow – isothermal boundary conditions – temperature distribution in Hartmann flow – Hartmann couette flow. Applications–Concepts in Magneto stastics. Classical MHD and Alfven’s wave, Alfven’s theorem, Frozen–n–phenomenon and equipartition of energy by Alfven’s wave. Classification of convection– Free, forced and mixed Free convective motion of viscous fluids Analytical solution for the Rayleigh– Benard convection in a Newtonian fluid. Analytical solution for the Benard–Marangoni convection problem in a Newtonian fluid. Galerkinsolution of Rayleigh– Benard convection problem for fluid–rigid boundaries. Galerkin solution of Rayleigh–Benard convection problem for rigid–free boundaries. Galerkin solution of Rayleigh–Benard convection problem for free– free boundaries subjected to isothermal and adiabatic conditions.

XXV Probability and mathematical statistics Axiomatic approach to probability, combinatorial problems. Conditional probability and independence. Random variables, expectation and moments. Discrete and continuous distributions. Binomial, Poisson, Normal, Uniform, Beta, Gamma, Chi-square and Bivariate normal distribution. Sampling distribution of mean and variance (normal population). Che by shev’s inequality, weak law of large numbers, De-Moivre—Laplace and Lindeberg—Levy Central Limit theorems. Descriptive Statistics: Introduction to statistical methods, frequency distributions, measures of central tendency and dispersion, moments and measures of Skewness and Kurtosis. Fitting of Binomial, Poission and Normal distribution, Theory of attributes independence and association, bivariate correlation and regression. General concept of Point estimation, unbiasedness, consistency, efficiency, sufficient statistics, Factorization Theorem, Completeness Rao-Blackwell Theorem, Cramer Rao Inequality. Maximum Likelihood method of estimation and method of moments, Interval estimation, confidence intervals for means, difference of means and variances. Testing of Hypotheses, uniformly most powerful tests, likelihood ratio tests. t, Chi-square and F-distribution. Tests of significance based on t, Chi-square and F. Analysis of variance.

XXVI Mathematical statistics Distributions of Random Variables: The probability set Function, random variables, The probability density Function, the distribution function, Certain probability Models, Mathematical Expectation, Some special Mathematical expectations, Che by shev’s Inequality, conditiona lprobability, Marginal and conditional distributions, the correlation coefficient, Stochastic Independence. Some Special Distributions: The Binomial, trinomial, and Multinomial Distributions, the Poisson

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RECOMMENDED STUDY MATERIALS

Distribution, The Gamma and Chi-square Distributions, the normal distribution, and the bivariate normal distribution. Sampling theory, Transformations of variables of the Discrete type, Transformations of the variables of the continuous type. The‘t’ and ‘F’ distributions. Extensions of the change-of-variable Technique, Distributions of order statistics, the moment generating function Technique, The distribution of c and nS2/_2, Expectations of Functions of Random variables, Limiting Distributions, Stochastic Convergence, Limiting Moment Generating Functions, The Central limit Theorem, some theorems on limiting Distributions.

XXVII Mathematical programming and design & analysis

Linear Programming, optimal solutions of linear programming problems. Duality in linear programming. The dual Simplex method. Integer Programming: Importance of integer programming problems. Dynamic programming, Application of dynamic programming, Bellman’s principle of optimality, solution of problems with a finite number of stages, Inventory control and solving linear programming problems. Network Analysis: Shortest path problem. Minimum Spanning Tree Problem. Maximum flow problems. Network Simplex Method. Project planning and Control with PERT-CPM. Non linear programming problems: The general Linear Programming problems of constrained maxima and minima. Quadratic Programming: General quadratic programming problem, Kuhn Tucker conditions of quadratic programming problems, Examples based on Wolfe's method and Beale's method Concepts of Experiments, Principles of Design of Experiments, Analysis of Non-Orthogonal Data, Two Way Data, Complete Block Designs. Factorial Experiments: Symmetrical, Asymmetrical factorial designs. Confounding, Partial-Confounding and Fractional Factorial Designs. Incomplete Block designs and their analysis. BIBD, PBIBD Construction and Analysis.

Unit Title of the books Unit I 1. Savita Arora and S. C. Malik: Advanced Analysis, New Age International Ltd.

2. Robert G. Bartle and Donald R. Sherbet: Introduction to Real Analysis, John Wiley and Sons. 3. R. R. Goldberg: Methods of Real Analysis, New Age International Ltd. 4. A. M. Bruckner, J. B. Bruckner, B. S. Thomson: Real Analysis - Prentice Hall , 1997

Unit II 1. J. B. Conway: Functions of one complex variable, Springer-Verlag.

2. S. Ponnusamy: Foundation of Complex Analysis, Narosa Publishing House. 3. Murray R. Spiegel: Complex Variables, Schaum's Outline Series.

Unit III 1. David S. Dummit and Richard M. Foote: Abstract Algebra, John Wiley and Sons.

2. J. B. Fraleigh: A first course in Abstract Algebra, Narosa publishing House. 3. 1. N. Herstein: Topics in Algebra, Wiley - Eastern. 4. V. K. Khanna and S. K. Bhambri: Abstract Algebra, Vikas Publication. 5. 1. S. Luther and 1. B. S. Passi: Algebra-Groups- Volume 1, Narosa Publishing House.

Unit IV 1. N.S.Gopalkrishna: University Algebra, Wiley-Eastern 1988.

2. N.S.GopaIkrishna: Commutative Algebra, Oxonian Press 1988. 3. Serge Lang: Linear Algebra, Addition-Wesley Publishing company. 4. Seymour Lipschutz: Theory and Problems of linear Algebra, Schaum's outline series.

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Unit V 1. William E. Boyce and Richard C. DiPrima: Elementary Differential Equations and Boundary Value Problems, Second Edition, John Wiley and Sons, Inc., New York. 2. Earl A. Coddington: An Introduction to Ordinary Differential Equations, Prentice-Hall India, 2001. 3. H. K. Dass: Advanced Engineering Mathematics, S. Chand and Company Ltd., New Delhi 1999. 4. Fritz John: Partial Differential Equations, Forth edition, Springer International edition, New York 2009. 5. Robert C. McOwen: Partial Differential Equations Methods and Applications, Pearson Education Inc., Indian branch Delhi, 2004. 6. Phoolan Prasad and Renuka Ravindran: Partial Differential Equations, New age International Publishers, New Delhi 2005. 7. George F. Simmons: Differential Equations with Applications and Historical Notes, Tata McGraw-Hill Publications, New Delhi 1985.

Unit VI 1. Theory of Ordinary and delay differential equations by R.D.Driver Kingston R.I., Nov,

1976(SpringsVerlag). 2. TheoryofordinarydifferentialequationsbyE.A.coddingtonandN.Levinson.

Unit VII 1. J. P. Chauhan: Differential and Difference equations, Garg Publishing House.

2. R. V. Churchill and 1. Vj. Brown: Fourier Series and Boundary value problems, Me Graw-Hill international. 3. Goyal and Gupta: Laplace transforms and Fourier transforms, Pragati Prakashan. 4. Murray J. Spiegel: Laplace Transforms, Schaum's outline Series. 5. “Special functions of Mathematical physic and Chemistry” I.N. Sneddon, of Longman Publications.

Unit VIII 1. DiscreteMathematicalstructureswithApplicationstoComputerScience,J.P.Tremblay&R.

Manohar,TATAMcGraw-HillEdition 2. GraphTheorywithapplicationstoEngineeringandComputerScience.NarsinghDeo,PHIPrentice-

HallIndia.

Unit IX 1. F.Chorlton,TextbookofFluidDynamics,CBSPublishers&Distributors.

Unit X 1. Mathematicalmodeling-J.N.Kapur 2. AnIntroductionof Bio-statistics- P.S.S.Sundararao 3. Mathematical modelsinbiology-anintroduction- ElizabethS.Allman,JohnA.Rinodes

Unit XI 1. OperationsResearch,S.D.Sharma,KedarNathRamNath& Co.Publishers,

2. OptimizationofSystemsReliability,1.F.A.Tillman,C.V.Hwang&W.Kuo,MarcelDekker Inc. EngineeringOptimizationTheoryandPractice,S.SRao,NewAgeInternationalPublications, Thirdedition. 3. ReliabilityEngineering,E. Balagurusamy,TataMcGraw-HillPublishingCompanyLimited.

4. OperationsResearchTheoryandAppliactions,J. K.Sharma,MacmillanPublications,4thEdition.

Unit XII 1)HigherEngineeringMathematicsbyB.S.Grewal,Khannapublications,36thedition. 2)NumericalmethodsforEngineersbyS.C.ChapraandRaymondP.CanaleTataMcGraw–Hill PublicationsFourthedition.

3)K.ShankarRao,“NumericalMethodsforScientists&Engineers”2ndEdition(2004)

Unit XIII 1. Anintroductionto TheoryofNumbers,G.H.HardyandE.M.Wright 2. ElementaryNumberTheory,NivenandZuckerman

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3. BruceBurndt-Ramanujan'sNoteBooksVolume-1to5. 4. EncyclopediaofMathematicanditsapplications,G.E.Andrews.

Unit XIV 1.AtreatiseontheAnalyticalDynamicsofParticlesandrigidbodies.byE.T.Whittaker(1965)

CambridgeUniversityPress. 2. ClassicalMechanicsbyE.A.Desolge,Vol.IandII(1982),John-Wileyandsons,NewYork. 3.ClassicalMechanicsAModernPerspectivebyV.BargerandMartin,Olsson(1995)McGrawHill, Inc.NewYork. 4. ClassicalMachanicswithintroductionto Non-linearoscillationandchaosbyV.B.Bhatia(1997) NarosaPub.House. 5.ClassicalMechanicsbyH.Goldstein(1980),NarosaPublishingHouse,NewDelhi 6. CalculusofvariationswithapplicationstoPhysicsandEngineering(InternationalseriesinPure andAppliedMathematics)byRobertWeinstock(1952)McGraw-Hillbookcomp.NewYork. 7. ClassicalMechanicsbyN.C.RanaandP.S.Joag(1991)TataMcGrawHill,NewDelhi.

Unit XV 1IntroductiontoTopologyandModernAnalysis, G.F.Simmons,McGraw-Hill,1963.

2. Functional Analysis, G. BachmanandL.Narici,AcademicPress,1966. 3. Introduction to Functional Analysis, A.E.Taylor,John Wiley,1958. 4. Functiona lAnalysis, B.V.Limaye,WileyEastern. 5.Linear Operators,Part-I,Interscience,N.DunfordandJ.T.Schwartz,1958. 6. FunctionalAnalysis,R.E. Edwards,HoltRinehartandWinston,1965. 7.FirstCoursein FunctionalAnalysis,C.GoffmanandG.Pedrick,Prentice-HallofIndia,1987. 8. FunctionalAnalysisandItsApplications,K.K.Jha,StudentsFriend,1986

Unit XVI ‘Topology’,byJamesR.Munkres,secondedition2002.

Unit XVII 1. Shanti Narayan: Cartesian Tensors ,S.Chandand Company, NewDelhi.

2. E.C.Young: VectorsandTensorAnalysis,MarcelDeccer,1994. 3. A.W.Joshi: TensorsandRiemanianGeometry. 4. C.E.Weatherburn: DifferentialGeometry. 5. A.Goetz:IntroductiontoDifferentialGeometry:AddisonWesleyPublishingCompany,1970.

Unit XVIII 1. Hadley,G.:LinearProgramming,NarosaPublishingHouse,6thedition,1995.

2. Kambo,N.S.:MathematicalProgrammingTechniques,AffiliatedEast-WestPressPvt.Ltd., New Delhi,Madras.

3. Swarup,Kanti,: OperationsResearch,SultanChand&Sons,NewDelhi,9thGupta,P.K.&Man MohanEdition,2001. 4.Murty,KattaG.:Linear&CombinatorialProgramming,JohnWiley& Sons,Inc.,1976(New York, London,Tronto). 5.Mangasarian,O.L.:NonlinearProgramming,TataMcGrawHillCompanyLtd.(Bombay, New Delhi),1st Edition,1969. 6. BazaraaMokhtar,S.:NonlinearProgramming,TheoryofAlgorithms,Wiley,New&Shetty, C.M. York,1979.

XIX 1. 1.W.H.BesantandA.S.Ramsey,ATreatiseonHydrodynamics,CBSPublishersand

Distributors,Delhi,1988. 2. 2. S.W.Yuan,FoundationsofFluidDynamics,Prentice-Hallof India,1988.

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XX 1. S. TimoshenkoandN.Goodier,TheoryofElasticity,McGraw-Hill,NewYork1970. 2. A.E.Love,ATreatiseontheMathematicalTheoryofElasticity,CambridgeUniversityPress, London,1963. 3.Y.C.Fung,FoundationsofSolidMechanics,Prentice-Hall,NewDelhi,1965. 4. I.H.Shames,Introductionto SolidMechanics,Prentice-Hall,NewDelhi,1975. 5. S.Valliappan,ContinuumMechanics,OxfordandIBHPublishingCompany,NewDelhi,1981. 6.MathematicalTheoryofElasticity,I.S.Sokolnikoff,TataMcGraw-HillPublishingCompanyLtd, 1977,

XXI 1.J.P.Trembley&R.Manohar,DiscreteMathematicalStructureswithApplicationstoComputerScience,Mc

Graw-HillBookCo.,1997. 2. J. L. Gersting,MathematicalStructurefor ComputerScience(3rded.),ComputerSciencePress,N.Y. 3.SeymourLepschutz,FiniteMathematics,McGraw-HillBookCo.New–York. 4.J.E.HopcroftandJ.D.Ullman,IntroductiontoAutomataTheoryLanguages&Computation, NarosaPublishingHouse,Delhi. 5.C.L. Liu,elementsofDiscreteMathematics,McGraw-HillBookCo. 6.N.Deo,GraphTheorywithApplicationstoEngineeringandComputerSciences,PHI,NewDelhi

XXII 1. R.B.Ash,RealAnalysisandProbability,AcademicPress,NewYork,1972

2. K.L.Chung,AcourseinProbability,AcademicPress,NewYork,1974. 3. R.Durrett,Probability:TheoryandExamples,(2ndEdition)DuxburyPress,NewYork,1996. 4. V.K.RohatgiAnIntroductiontoProbabilityTheoryandMathematicalStatistics,WileyEastern Ltd.,NewDelhi,1988(3rdPrint). 5. S.I.Resnick,AProbabilityPath,Birhauser,Berlin,1999. 6. B.R.Bhat,ModernProbabilityTheory(3rdEdition),NewAgeInternational(P)Ltd,New Delhi,1999 7. M.Fisz,ProbabilityTheoryandMathematicalStatistics,JohnWileyandSons,NewYork, 1963.

XXIII 1. Hogg.,R.Vand:IntroductiontoMathematicalStatistics,MacMillan,2002.

2. Goon,A.M.:Fundamentalof Statistics,Vol.1,7thEdition,1998. 3. Fisz,M.:ProbabilityandtheMathematicalStatistics. 4. Feller,W.:IntroductiontoProbabilityanditsApplications,Vol.1.

XXIV

XXV 1. Feller,W, Introduction toProbabilityanditsApplications, WileyEastemPvt.Ltd.Vol.1, (1972). 2. RobertV.HoggandAllenT.Craig,Introduction toMathematical Statistics,ForthEdition, MacmillanPublishingCo.,Inc.,NewYork,1989,(Chapter1to5).

XXVI 1. Kempthorne: The Design and Analysis of Experiments, JohnWiley 2. Das&Giri: Design and Analysis of Experiments, Wiley Eastern 3. Day:IncompleteBlockDesigns,WileyEastern 4. Montgomery: Design and Analysis of Experiments, John Wiley 5. S.D. Sharma: Operations Research, Kedar Nath Ram Nothandco. 6. Kanti Swarup, P.K. Gupta and Manmohan : Operations research, S.Chand &Co. 7. Hamady Taha: Operations Research, Mac Millan Co 8. S.D.Sharma:NonlinearandDynamicprogramming,KedarNathRamNathandCo. 9. G. Hadley: Linear programming, Oxford and IBH Publishing Co. 10. S.I.Gass:LinearProgramming,McGrawHillBookCo.

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D. COMPUTER SCIENCE (Candidate will have the option to select any five units from the following list of units as per specialization or may submit any other relevant topic in coordination with the supervisor)

Unit Contents Unit I Natural Language Processing

Introduction to Natural Language Understanding, An Outline of English Syntax, Grammars and Parsing, Grammars for Natural Language, Toward Efficient Parsing, Ambiguity Resolution: Statistical Methods, Linking Syntax and Semantics, Ambiguity Resolution, Scoping and the Interpretation of Noun Phrases.

Unit II Compilers Introduction, types of Parsers, LL (k) and LALR (k) parsers, three address codes. Introduction to code generation, simple code generation algorithm, DAGs Introduction to Code Optimization, basic blocks and flow graphs, common sub-expression elimination, loop optimization, loop invariant computations, dead code elimination, code movement

Unit III Digital Image Processing Digital image fundamentals: image digitization, sampling and quantization, image resolution, color perception & processing, image processing: pixel based transformation, geometric transformation, local processing restoration, binary image processing: thresholding, run length encoding, distance transforms, medial axis transforms, morphological operations, region segmentation & representation: split & merge algorithm, region growing, image filtering histogram modification, linear and Gaussian filters, contours , digital curves, poly line splitting, Hop_ Along algorithm, Conic & Splines Hough transform, Fourier description, textures: statistical syntactic and modelbased methods, Texture image analysis, image transforms :Fourier, Hadamard, discretecosine, wavelets and other orthogonal transforms, compression image (predictive compression methods, vector quantization, hierarchical & progressive methods, JPEG &MPEG), Motion picture analysis.

Unit IV Wireless Technology. WSN: Design issues, System Architecture, Sensor Network OS Tiny OS, Nes Language, Distributed data processing, Synchronization and localization, Communication and routing, Security issues , services and applications Mobile Ad-hoc Networks: Location Management Schemes, Routing.GSM and satellite Communication: Architecture, hand-off and power management. Wireless Network Standards & Protocols: 802.11.X, 802.16.x, 802.15.X, Comparison802.11a, 11b, 11g, Challenges for MAC, DCF and PCF, WEP& EAPQoS in wireless Network: Parameters Throughput or bandwidth, Delay or latency Delay variation (delay jitter), Loss or error rate

Unit V Network Security Network threats and attacks, Security Services, Number Theory Concepts, Crypto graphic algorithms, Network Security Protocols, System Security, Security research in wired, wireless and ubiquitous networks, Security Standards and RFCs

Unit VI Artificial Intelligence AI problems, AI intelligent agents: Agents and Environments, the concept of rationality, the nature of environments, structure of agents, problem solving agents, problem formulation. Searching: Searching for solutions, uniformed search strategies, Heuristic functions. Constrain satisfaction problems: Game Playing Alpha-Beta pruning, Evaluation functions, cutting of search, Knowledge Representation & Reasons logical Agents, logic, propositional logic, Resolution patterns in propositional logic, Resolution, Forward & Backward Chaining, Planning – Classical planning problem, Language of planning problems, Expressiveness and extension, planning with state.

Unit VII Language Translation Language Processing: applications and key issues; lexicon and morphology; Phrase structure grammars and English syntax; Part of speech tagging; Syntactic parsing, top down and bottom-up parsing strategies; Semantics, Word Sense Disambiguation, Semantic parsing; Information retrieval and Question answering; knowledge representation and reasoning, local discourse context and reference

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RECOMMENDED STUDY MATERIALS

Unit VIII Machine Learning Designing a Learning system, Learning Process, Learning methods, Forms of learning, Induction learning, Learning with complex data, learning with Hidden variables, Parametric-Nonparametric methods, Multivariate methods, Feature extraction, clustering, Decision tree, Artificial Neural networks, Self Organization Map, Regression, Radial Basis Function networks, Function Approximation, Hopfield models Evaluating Hypotheses, Computational Learning theory, Instance based learning, rule based learning, Analytical Learning, Reinforcement learning, Hidden Markov Models, Probability, classification, Linear Discrimination.

Unit IX Graphics & Visualization Picture analysis, Modeling: 2D, 3D Geometric modeling and transformations, projections, Clipping, curves and fractals. Illumination models and Rendering: Light, Ambient Light, Diffuse reflection, Specular reflection, Shading algorithms, Colormodels, Ray tracing, Texture mapping. Scientific Visualization: Methods of Scientific Exploration, Data Aspects and Transformations, Time-Tested Principles for Good Visual Plots, Tone Mapping, Matters of Perception, Visualizing Multidimensional Data, Scalar Data Visualization, Vector Data Visualization. Graphics User Interfaces, image manipulation and storage, advanced modeling techniques.

Unit X Advanced Algorithms and Applications Problem solving, Probabilistic analysis and randomized algorithms, Perfect Hashing, TheFloyd-Warshall algorithm, Johnson's algorithm for sparse graphs, NP-hard problems, Approximation algorithms, Online algorithms and competitive analysis. Linear-Programming Algorithms: Structure of Optima, Interior Point. Computational geometry: convex hull. Random Walks and Markov chains

Unit XI Data warehousing and Mining Data Mining Tasks, Data Warehouse (Multidimensional Data Model, Data Warehouse Architecture, Implementation), Data Warehousing to Data Mining, Data Preprocessing: Why Preprocessing, Cleaning, Integration, Transformation, Reduction, Discretization, Concept Hierarchy Generation, Descriptive Statistical Measures, Classification: Decision Trees, Model Over fitting, Bayesian Classification, Rule-based classification, Nearest Neighbor Classifier, Classification by Back-propagation, Support vector machines, Association Rule Based, Other Classification Methods, Prediction, Classifier Accuracy, Cluster Analysis: K-means, Agglomerative Hierarchical Clustering, DBSCAN, Association Rules: Apriori algorithm, FP-growth algorithm, Advanced techniques, Data Mining software and applications: Text mining (extracting attributes/keywords, structural approaches - parsing, soft parsing, Bayesian approach to classifying text), Web mining(classifying web pages, extracting knowledge from the web), Data Mining software and Applications

Unit XII Parallel and Distributed Systems Terminology of Parallel and Distributed Computing, Parallel and Distributed Architectures, Parallel Performance, Shared Memory and Threads, Parallel Algorithms, Message Passing, Distributed Systems, Distributed Coordination, Distributed File Systems, Distributed Shared Memory, Cloud Computing, Computational Grids and Applications

Unit Title of the books Unit I 1.James Allen, “Natural Language Understanding”, Pearson Education, 2nd Edition

2.Akshar Bharati, Vineet Chaitanya, Rajiv Sangal, “Natural Language Processing- APaninian Perspective”, PHI 3.Christopher D. Manning and Hinrich Schütze. 1999. Foundations of StatisticalNatural Language Processing. MIT Press.

Unit II 1. Alfred V. Aho, Ravi Shethi, Jeffrey D Ullman,”Compilers- principle, techniques and tools”, Pearson Education, 2006

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2. V Raghvan,”Principles of Compiler Design”,Tata McGraw Hill,,2010

Unit III 1. Rafael C Gonzalez, Richard E Woods, “Digital Image Processing”, Prentice HallPublisher, 2008, 3rd Edition 2. William K Pratt, “Digital Image Processing”, John Willey (2001) 3. Millman Sonka, Vaclav hlavac, Roger Boyle, Broos/colic,”Image ProcessingAnalysis and Machine Vision”, Thompson Learning (1999). 4. A.K. Jain, “Fundamentals of Digital Image Processing”, PHI, New Delhi (1995) 5. Chanda Dutta Magundar,”Digital Image Processing and Applications”, PHI, 2000

Unit IV 1. Holger Kars,” Protocols and architectures for WSN” , Wiely publication. 2. M Jochen Schiller, “Mobile communication”, Person Publication. 3. Mathew Gast, “802.11 wireless Networks the definitive guide”, O’Reilly.

Unit V 1. William Stallings, “Cryptography and Network Security”, Fourth Edition,PearsonEducation 2007. 2. Behrouz A. Forouzan, “Cryptography & Network Security”, TMH 2007. 3. Robert Bragg, Mark Rhodes, “Network Security: The complete reference”, TMH

Unit VI 1. Stuart Russel,Peter Norvig, “Artificial Intelligence – A Modern Approach”, SecondEdition, PHI/Pearson Education. 2. Patrick Henry Winston, “Artificial Intelligence”, 3rd Edition, Pearson Education.

Unit VII 1. Christopher D. Manning and Hinrich Schütze, “Foundations of StatisticalNatural Language Processing”, MIT Press, 1999. 2. James Allen, “Natural Language Understanding”, Pearson Education, 2ndEdition

Unit VIII 1. Simon Hhaykin, “Neural networks - A comprehensive foundations”, PearsonEducation 2nd Edition 2004. 2. Ethem Alpaydin, “Introduction to Machine Learning”, PHI 3. Tom Mitchell, “Machine Learning”, MGH

Unit IX 1. Peter Shirley, Ashikhmin Gleicher et. al.,”Fundamentals of Computer Graphics”, A. K.Peters Ltd., 2005 2. Hearn and Baker,”Computer Graphics”, PHI 3. Van Dan Feiner, Hughes, Foley, “Computer Graphics: Principles and Practice”, PHI

Unit X 1. Thomas H. Cormen, Charles E. Leiserson, Ronald L. Rivest and Clifford Stein,“Introduction to Algorithms,” Third Edition PHI 2010.

Unit XI 1. J. Han and M. Kamber, “Data Mining- Concepts and Techniques”, 2nd Edition,Morgan Kaufmann, 2006. 2. M argaret H. Dunham,” Data Mining Introductory and Advanced Topics”,Prentice Hall 3. P. Tan, M. Steinbach and V. Kumar, “Introduction to Data Mining”, AddisonWesley, 2006.

Unit XII 1. G Coulouris, J Dollimore and T Kindberg, “Distributed Systems Concepts andDesign”, Third Edition, Pearson Education. 2. Kai Hwang, Faye A.Brigs, “Computer Architecture and Parallel Processing”,Mc Graw Hill

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E: ZOOLOGY

(Candidate will have the option to select any five units from the following list of units as per specialization or may submit any other relevant topic in coordination with the supervisor)

Unit Contents Unit I Molecular biology

Regulation of gene expression in Prokaryotes and Eukaryotes; Operon Concept; Environmental regulation of gene expression, regulation of gene by steroid hormones in invertebrates (insects), Vertebrates (Mammals).Onco-genes and cancer on molecular basis.

Unit II Immunology Antigen; Structure and functions of different classes of imunoglobins; primary and secondary immune response lymphocytes and accessory cells. Humoral and cell–mediated immunity; MHC; mechanism of immuneresponse and generation of immunological diversity.

Unit III Environmental pollution Different types of pollutant – acute and chronic toxicity; Bioassay LC50 values environmental pollution and their impact on animals, Biomagnifications, Detoxification mechanism; synergistic and antagonistic effects of pollutants microbial and environmental degradation of pesticides. Environmental Impact Assessment.

Unit IV Microbial genetics Lysogeny and lytic cycle in bacteriopages, Bacterial transformation, Host cell restriction, transduction, complementation molecular recombination, plasmids and bactrio phage based vectors for DNA and genomic libraries.

Unit V Biotechnology Microbial fermentation, organic Microbes in decomposition and recycling process, isolation of DNA and RNA from Animal tissues, Transgenic animals.

Unit VI

Crustacean endocrinology and reproduction

General biology of crustacean: General characters of the phylum Arthropoda, Class Crustacea: General characters; Classification; Types, Various body systems Osmoregulation, Feeding mechanisms, Diversity and conservation of Crustacea. Neuro-endocrine system of crustacean: Neuro secretory system of crustacean brain – Sinus gland X-organ complex, Y-organ Hormonal regulation in molting, growth and reproduction Hormonal manipulation of crustacean reproduction Mechanism of vitellogenin synthesis Fertilization Various types of parental care of eggs Stages of embryonic development, Metamorphosis; Different larval forms. Aquaculture of crustacean: Prawn culture, Crab culture (fattening), Lobster culture Site selection and preparation of culture ponds; Physicochemical factors, Hatchery, production of seeds, Food, Live feed, Artificial feed, Balanced diet (iso-nitrousandiso-caloric) Predators and Parasites in aquaculture, Economics of Aquaculture. Toxicology and pathology of crustacean: Xenobiotics substances and their toxic effects on crustacean, Toxicity tests–Causes for different diseases - Disease causing pathogens and their preventive measures in aquaculture of crustacea–Cellular stress and

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Immuneresponses: Defence and Detoxification systems, Wound healing, Apoptosis-Probiotics in health and growth of crustacean. Genetic engineering and biotechnology of crustacean: Molecular Cytogenetics of Crustacean; Isolation and Purification of DNA and RNA. Isolation and Purification of Enzymes and Hormones. Recombinant DNA technology; Blotting techniques, PCR techniques, Gel documentation, Proteomics, Genomics and Bio-informatics of crustacea.

Unit VII

Human genetics Identification of human chromosome characterization. Various Banding techniques (G,C,Q,R). Designating structural chromosomal abnormalities by break points and band composition and sister chromatid exchange studies. Chromosomal syndromes; Autosomal abnormalities, Down syndrome, Edward syndrome, Patau syndrome, Cri-du-chat syndrome. Sex chromosomal syndrome; Klinefelter’s syndrome, Turners syndrome, multiple XXX syndrome, XYY male. Prenatal diagnosis: Buccal smear test, Amniocentesis, Chorionic villi and fibroblast cultures. Human Biochemical Genetics - Inborn errors of metabolism – Amino acid metabolism, Phenylketonuria. Disorders of Purine metabolism: Lesh-Nyhan syndrome. Disorders of carbohydrate metabolism, Galactosemia, Immunogenetics; Introduction to immune response; the cellular basis of immune responses; Immune deficiency disorders. Endocrine Genetics; General principles of hereditary diseases: Gene action in Endocrine glands. Pituitary–Diabetesmellitus. Parathyroid–Hypoparathyroidism. Adrenal–Congenital Adrenal. Hyperplasis, Sexual development– Testicular feminization syndrome, Male Hypogonadism. Mutation:Types of mutations, Molecular basis of mutations. Genetic Engineering: gene manipulation. Techniques –Cutting andjoining DNA molecules. Cloning in E.coli–Plasmids as cloning vehicle for use in E.coli of cloned DNA. Cloning in organisms other than E.coli, Cloning in Yeast. Application of recombinant DNA technology in biology and medicine.

Unit VIII Pollution biology Environmental Xenobiotics; source, factors responsible for distribution, accumulation and their effects of plants and animals. Effect of environmental chemicals on species diversiy mutagencity, teratogenicity, carcinogenicity. Toxicology: synergism and antagonism of ions–Bioassay of toxicity using animals, effect of ecological factors of the aquatic medium on toxicity, toxic substances of aquatic medium. Ecotoxicology of terrestrial organisms; Effect of ecological conditions of terrestrial environment on toxicity– Evaluation of terrestrial toxicity by using soil invertebrates. Methodological problems of aquatic and terrestrial toxicity; Toxicological statistics; Environmental risk assessment.

Unit IX Environmental physiology Environment: Major biomes with reference to India, Renewable and nonrenewable resources, Physico-chemical aspects of rivers, estuaries and terrestrial environments, Problems of water pollution in India. Energetics: Plant, animal interaction and stability of the environment. Ecological energetics: Food chain, food webs, energy transfer through trophic chains and ecological efficiencies in aquatic ecosystems.

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Plant microbial interaction: Physiological adaptations of animals to the limiting factors, oxygen, pressure, temperature and light. Monitoring of pollution: Solid, sewage, effluents, their sources, disposals and their treatments, recycling of wastewater. Toxic inorganic and other constituents affecting waterquality; such as colour, turbidity, BOD, COD, alkalinity, hardness, TSS, chlorinity; their estimations and their levels on monitoring water pollution. Exposure to pollutants and risk assessment, exposure assessment, etc. assessing Carcinogenic and non-carcinogenic risks. Eutrophication and problems of weeds and their control. Dynamics of pollutants: Absorption, distribution and excretion of toxic substances. Biodegradation of organic compounds such as pesticides, heavy metals and toxic organics-Toxic effects of pollutants such as pesticides, heavy metals and toxic organics on biological systems. Food intoxication by pollutants and microbes; food spoilage, diseases, food preservation processes. Industrial applications of microbes: Microbes in the synthesis of amino acids, organic acids & antibiotics, Microbial insecticides, biopolymers and biosensors-Microbial role in bioleaching and recovery of minerals and metals, Plant biomass to fuels, Bio –deterioration management.

Unit X Wild life ecology and management Systematic biology: Taxonomy; Species concept theories, Speciation; New species description, assessment techniques, evaluation; importance of taxonomy; International Code for Zoological Nomenclature (ICZN). Biodiversity: Biodiversity-kinds of biodiversity; Biogeography continental shift, zoogeography, biodiversity hot spots, endemicity; Biodiversity assessment; Endangered species, Indian Wildlife Protection Act 1972, And International Red list species criteria, concept and assessment. Field sampling techniques: Population estimation concept, line transect, quadrate sampling; Animal trapping techniques-pitfall, funnel, Sherman traps; marking and recapture techniques; use of indirect evidences in species inventory; Basic methods in behavioural and food habit studies; Wildlife management techniques. Ecosystem service: Animal plant interactions- pollinators, seed dispersal, biological pest control, vector; Wildlife products-food, medicine, Germplasm, domestication; Ecological balance; prey-predator relationships, herbivory and scavengers. Man and biodiversity: Development projects, River valley, mine, power projects; impact assessment-methodology, GIS tools; ill effect of pesticides; bioaccumulation; biomarkers; Pollution Control Boards (PCBs), regulations, standards; Conservation laws-wildlife, forest and water.

Unit XI Limnology Origin of lakes, ponds and estuaries, Classification of lentic and lotic environments, Physico-Chemical Character of ponds, lakes and rivers; Characteristics of estuarine environment; Productivity and energy flow in the freshwater environment Cycling of nutrients in the freshwater environment. Pollution of the Freshwater environment and its effects on organisms Waterborne pathogens and diseases; A general study of fresh water organisms (Plankton, Nekton & Benthos), Freshwater fisheries of India, Major carps of India and recent trends in their culture practices.

Unit XII Advances in insect biology and pest management

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Biology: Overioles and testis follicles, their number in different orders and basic histomorphology; male & female accessory, glands, their secretion and modes of sperm transfer and reception (spermatophores & spermathecae) Viviparity & Viviparious insect, factors regulating parthenogenesis and polymorphism with special reference to homoptera: Isoptera and Hymenoptera. Ecology: Abiotic & Biotic factors in biology, Abundance & distribution of insects with special reference to diapause. Interspecific and intraspecific interactions with special reference to insect migration & pest outbreak. Insect life table and its application methods of assessing insect pest/populations; plant resistance. Chemical control of Insect Pests: Classification of insecticides, modes of action of insecticides; Mechanism of insecticide resistance: Chitin inhibitors and their efficacy in pest management; recent trends in pesticide application technology. Non-chemical control and Insect pests: Dynamics of prey-predator interaction and host- Parasite/parasitoidinter-actions-1geneticand semi-chemical bases of insect pest control Neurophormone Juvenodids and Ecdysoids in insects pest management.

Integrated Pest Management (IPM): Principles of IPM programme its objectives, strategy and tactics ecological basis to pesticide application. Systems analysis. Recent trends in IPM.

Unit XIII Insect pest control and toxicology Insect pests, Types of Damage to Plants by insects, Pest surveillance and forecasting pest Outbreak, Assessment of insect population, Estimation of damage caused by insect pests to crops. Insect pest control; Natural control, Biological methods, Microbial methods, Chemical methods, Chemosterilant, Insect attractants, repellents, Antifeedants, Integrated pest control. Insecticides, Insecticides formulation, Classifications, Mode of action, Inorganic insecticides, Organic insecticides, Insecticides of Plant Origin. Principles of toxicology of insecticides, General Bioassay of pesticides, Insecticide residues, Resistance of insecticides, Factors influencing effectiveness of insecticides. Statistics of Toxicology: Median Lethal Dose, Behren’s methods, Graphical method, Rapid Approximate method by Huson, Finney’s Method, Abbott’s method.

Unit XIV Aquaculture and fisheries Introduction; Indian and World Aquaculture-Role, Constraints, remedial measures and other related problems, Importance of Aquaculture–Fish products and by-products. Major inland capture fishery resources in India-Lake and reservoir fisheries–Nursery system in Estuaries and Brackish water and its fishery resources in India-Marine major and minor fishery resources in India and Worlds’ fin and shellfishes. Monoculture-Polyculture-extensive, intensive-Integrated fish farming–Paddy cum fish culture –fish and prawn culture in fresh water ponds, Fin fish and shellfish culture in Brackish water ponds, Ornamental fish culture. Taxonomy of Live feeds, General collecting methods-Culture and Nutritional value of Rotifers, Artemia, Copepods and Daphnia–Molluscan culture and its status-Culture of zooplankton, Sea weeds and their importance. Cryo preservation techniques for Live feed Bio-enrichment technique, Applied Genetics of cultivated fishes–Regulation of vitellogenesis in shell and fin fishes.

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RECOMMENDED STUDY MATERIALS

Unit XV

Proteomics and Molecular Cell Physiology Structural organization of Prokaryotic and eukaryotic cells with all cell organelles and their functions –Principle and applications of: Electron Microscopy- SEM, TEM and AFM; Multi-photon Confocal microscopy, Inverted Microscopy, Fluorescent microscopy and Immuno-histo-chemistry. Basic Principles and applications of animal and microbial cell culture mdedia types, preparation and their applications. Specimen preparation, collection, transport and maintenance. Current scenario of Stem cell Research. Outline of Chromosome, Genome, Gene and DNA – DNA as genetic material, DNA replication-DNADamage-DNA repairing Mechanisms–Gene Cloning Strategies. Transfer of animal, gene into bacterial cell for over expression. Molecular cloning Vectors used in Animal Biotechnology and Over expression system of prokaryotes (pETseries). RNAi technology and its impact in medical sciences. Gene therapy and its application. DNA Micro array technology and its application. Comparison of Transcription and translational process between prokaryotes and eukaryotes. RNA Splicing mechanism–Principles and methods of Chromosomal and Plasmid DNA and RNA isolation and purification from bacteria and mammalian cells, Agarose gel electrophoresis and DNA sequencing methods-Molecular biology of Cancer: Types and Current status of cancer diagnostic tools and treatment strategies. Outline about Apoptosis. Introduction to Bioinformatics and applications of bio-informatics tools in protein science. Proteomics: types and applications. Protesome of Normal and Cancercells. Significance of Cancer proteomics, Pharmacoproteomics and Toxicoproteomics. Proteomics techniques: Principle, method and applications of SDSPAGE, Native gel electrophoresis, Immuno electrophoresis, Western blotting, Mass Spectrometry, MALDITOF analysis, Peptide sequencing: Edman’smethods. Applications of Animo acidanalyzer. Proteomic Databases-types– Primary and secondary databases. Significance of protein Sequence comparison in evolutionary studies. Prediction of secondary structure of protein and their related proteomic databases and packages. Protesome of Escherichia coli and Homosapiens. Current status of proteomic research in human healh diseases.

Unit Title of the books Unit I 1. DuprawE.J.1969: Celland Molecular Biology, Academic press, Oxford & IBH.

2. J.H.Taylor1965:perspectivesinmodernbiology:Selectedpapersinmoleculargenetics: Academic Press, New York.

3. KavithaBAhluwalia1991: Genetics–WileyEasternLtd.,NewDelhi. 4. Beyer, A.L.et.al.1979: Moleculargenetics,partIII:Chromosomestructure (ed)Taylor,J.H. AcademicPress, NewYork. 5. R.C.DalelaandS.R.Verma1990: AtextbookofGenetics,10thed.Jaiprakasannath&Co,

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Meerut. 6. Freifelder,D-1987:MolecularBiology2nded. Jones&Bartlett,Publ. Boston.

Unit II 1. Capeuter, P.L.1975, Immunology and serology3rded.W.B. SawndersCo.

Philadelphia. 2. Bellanti, J.A.1971: Immunology,W.B. Sawnders Co.Philadelphia. 3. Eisen., H.N.1973:Immunology, Harper and Row publishers,Inc.,Hagerstown,Maryland. 4. Mayor,M.M. 1973:the Complement system Sci.Am.229:54 5. Dutcherlony,O.1968: HandBookofImmunodiffusionandImmunoelectrophoresis. Ann. Arbor science publishers,Ann. Arbor Michigan. 6. Weir, D.N. 1967: Hand Book of Experiment and Immunology. Blackwell

Scientific publications, Oxford and Edinburgh. 7. Power,C.B.andH.T.Daginawala1990;GeneralMicrobiology,Vol.I and III Himalaya

Publishing House, NewDelhi.

Unit III 1. BernardJ.Nebel:1987: Environmental Science. The way world works 2nded. PrenticeHall, Inc. Englewood, Cliffes, NewJersey.

2. DanielD. Chiras1985:EnvironmentalScience–A frameworkfordecisionmaking2nded.,The Bengamin cummings publishing Co., Inc. Meulopark,California.

3. Smith,R.L.1977:ElementsEcologyandfieldbiology,HarperandRowpublications,New York.

4. MonneyH.A.andM.Goddon–1983: Disturbanceandecosystems. Sprwgerverlag, New

York. 5. Moran,J.M.Moran,M.D.andJ.H.Wiersma1980:IntroductiontoEnvironmentalScience,

H.W. Freemanand Co.Sanfrancisco,U.S.A. 6. Stewart,C.P.andA.Stolaman1962:Toxicology:Mechanism and Analytical methods, Vol.I AcademicpressNewYork. 7. Chawlett, E.T.1975:Environmental protection,Tata Mc GrawHill,New Delhi.

Unit IV 1. R.C.Dubyand D.K, Maheswari1999: A text book of microbiology, S. Chand and

Co., New Delhi. 2. M.J. Pelczar,JR.,Chan, E.C.S. and N.R. Krieg1996:Microbiology, Tata McGraw– Hill publishing Co.,Ltd., New Delhi. 3. Moat,A.G.and Foster, J.N.1995:MicrobialPhysiology,3rded.,Wiley– LissNewYork. 4. Friefelder, D.1987: MicrobialgeneticsJonesandBartlettpublication,Boston. 5. Freeman, B.A., 1979:TextbookofMicrobiologyW.B.,Saunder and Co. 6. DulbucoD and Ginsberg, E1980-Microbiology,Harper&Co.

Unit V 1.Primrose, S.B.1991:Molecularbiotechnology,2nded. Oxford, Blackwell Scientific

publishers. 2. Morgan,J. and Welan, W.J. 1979 : Recombinant DNA and Genetic

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experimentation. Pergamon press, Oxford, NewYork. 3. Beers,R.F.and BassetE.G.1977.Recombinant Molecules, RavenPressNewYork. 4. R.H.Pritchand&Holland,I.B.1985: Basiccloning Techniques a Manual of

experimental procedures. Blackwell Scientific publications, Oxford, London. 5. Williams,J.C.1981: Thepreparation andscreeningofcDNAclonebank. Genetic Engineering Vol.I(ed.Williamson,K) Academic press, London. 6. KashavTrehan1990:Biotechnology WileyEasternLtd., NewDelhi, Bangalore.

Unit VI 1. Crustacean Aquaculture, Mc Vey, J (Ed.), CRCPress.

2. Disease of Cultured Penaeid Shrimp in Asia and The United States, Fulks,W & Main,K.L (Eds.), Argent Laboratories Press. 3. Intensive Shrimp Production Technology, Wyban, J.A. &Sweeney, J.N. (Eds.), Argent Laboratories Press. 4.Standard Method for the Nutrition and Feeding of Farmed Fish and Shrimp, Albert GJT acon (Ed.), Argent Laboratories Press. 5. Gene Expression and Manipulation in Aquatic Organisms, Ennion, S.J. &

Goldspink, G(Eds.), Cambridge University Press. 6. Molecular Biology and Toxicology of Metals, Rudolfs K Zalups & James

Koropatnick (Eds.),Taylor and Francis 7. Crustacean Farming: Ranching and Culture, John F. Wickins & Daniel O.C. Lee

(Eds.), Black well Science. 8. Microscopic Anatomy of Invertebrates, Vol. 10. Decapod Crustacean, Harrison, F.W. & Humes,A.G. (Eds.), 9. Advances In Molecular Ecology, GaryR Carvalho (Ed.), ISOPress, Ohmsha NATO Science Series. 10.Practical Hand book of Biochemistry and Molecular Biology, Gerald Fasman(Ed.), CRC Press. 11.Aquaculture Principles and Practices, Pillay, TVR(Ed.), FishingNews Books,USA. 12.Fish and Fisheries of India, Jingran,VG.(Ed.), Hindustan Publishing Corporation, NewDelhi. 13.Arthropoda Crustacea, In: Reproductive Biology of Invertebrates, Adiyodi K.G & A. diyodi, R.G. (Ed.),Wiley. 14.Chemical Contamination in the Human Environment, Lippman, M & Schles Esger, R. B. (Ed.), Oxford Press. 15.Toxicology Testing Handbook, Jacobson-Kram, D & Keller, K. A. (Ed.), DekkerInc. 16.Environmental Chemistry,7thedition,Manahan,S.E(Ed.),LewisPublishers 17.Hand book of Eco-toxicology, Holfman,D.J.,Rattner,B.A., Burton(jr.),G.A., &Cairns (jr.),J. (Eds.),LewisPublishers. 18. Biodiversity, Rallapalli, R & Bali, G (Ed.), APH Publishing Corporation. 19.Environmental Biotechnology: Principles and Applications, Rithmann, BE & Mc Carty, PL (Ed.),McGraw-Hill.

Unit VII 1. Text book of Endocrinology–Robert H.Williams. (1974 & 1985) W.B.

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Saunder’sco., Philadelphia 2. Duncan’s Disease of Metabolism–P.K. Bondy and L.E. Rosenberg (1974) W.B.

Sounders Co., Philadelphia. 3. Vogel R and Rohroborn C(1970):Chemical ,mutagens in mammals and man. Springer– verlag, Berlin. 4. Brusick,D (1980): Principles of genetic toxicology, -PlenumPress. 5. Genetic Engineering & Biotechnology–V.L.Chopraand Auswar Nasim, Oxford & IBM Publishing Co., Pvt. Ltd., NewDelhi, 1990 6. Biotechnology–KeshavTrehan. Wiley Eastern Limited, New Delhi, 1990. 7. Reproductive Genetics & Law: Sherman Elias & George J. Annas year book Medical Publishers Inc.,Chicago, 1987. 8. Human chromosomes–Orlando J.Miller, Eeva Therman–Springer Pub.(2001) 9. Principles of Medical Genetics Thomasd. Gelebrter Franci S .Collins, Williams & Wilkin’s IB

Unit VIII 1. Smith, J.M.1974,Models in Ecology, The University Cambridge.

2. Patten B.C.1971, 1977Systems analysis and simulation ecology 4vols. Academic Press, New York. 3. Pitts J.N.Jr. and Metcal R.L. (Eds.) 1969. Advances in environmental Sciences and

Technology Vol.1 Wiley– Interscience. 4. Butler G.C. (ed) 1978 Principles of Ecotoxicology. John Wiley and sons New York. 5. Moriathy F,1975, Pollutions and animals A factual perspective Allen and Unwin, London. 6. Warren, C.E.1971, Biology and water pollution control W.B. Saunders Co., Philadelphia, U.S.A. 7. Meoney H.A. and M. Godron (Ed) 1983. Disturbance and Ecosystems Springer–verlag. 8. Levins, R.1968,Evolution in changing Environment Princeton University Press. 9. MastumuraF, 1980, Toxicology of insecticides plenumpress, London. 10. Edwartds,C.A.(ed) 1973 Environmental pollution by pesticides plenum press–London. 11.Stewart, C.P.and A.Stalman(eds.) 1961.Toxicology–Mechanisms and

Analytical methods Vols.II Academic Press–London. 12. Karmondy, E.J.1974 Concepts of Ecology prentice Hall, NewDelhi. 13.Suess, M. J.(ed) 1982. Examination of water for pollution control Vol.I. II and III Pergamon Press, NewYork. 14.WoodwardF.I.and J.E. Shely1983. Principlesand measurements in environmental Biology Butler Worths–London. 15. Poole,R.W. 1974. An introduction to quantitative Ecology, McGrawHillBook Co., Tokyo. 16.Smith R,Z.1980, Ecology and field Biology Harper and Row Publication, NewYork. 17.Usha M.B. and M.H. Williamson(eds.) 1974 Ecology stability, Champion and Hall, London. 18.Davis, D.E.(ed)1974, Behavioural and ecological factors, Hutchinson and Ross Inc. U.S.A.

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19. Cairns, J.(ed)1980.The recovery process in damaged ecosystems Ann Arbor Science, Inc. Ann. Arbor Michigan. 20.V.V. Metelev.A.I.Kanaevand N.G. Dzasohova1971 Water Toxicology, Amerind Publishing Co., New Delhi.

Unit IX 1. Alabaster and Lloyd.,Water quality criteria for fresh water fish

2. Alison Leadlay Brown.,1971.Ecology of fresh water.,Heineman EducationalBooksLtd., London

3. Allen,H.Bentonand W.E. Warner.,1976,Field Biology and ecology, TataMc.GrawHill Publ. Co.,NewDelhi.

4. Bell Davidson and Emglie Smith. Tex tBook of Physiology 5. Brown,A.W.A., Ecology of Pesticides 6. Butler, G.C. (Ed.) Principles of Ecotoxicology, JohnWileyand Sons, Newyork. 7. Dara, S.S., A text Book of Environmental Chemistry and Pollution Control 8. Eckert, R.,and D. Ball. Randall.,1983. Animal Physiology. IIE ditionW.H. Freeman and Co. 9. Frederic, W.Oeheme and Marcel Dekker (Ed) Toxicology of Heavy Metalsinthe

Environment. PartI&II,IVC,NewYork. 10.Goel, P.K., Water pollution, Causes, effects & Control 11.Hoar,W.S.1983. Generaland Comparative Animal Physiology. III.Edition., PrenticeHallIWC Hutchinson,G.E.1978. An Introduction to Population Ecology.,Yale Univ. Press, New Haven., CT.USA. 13.John Vernberg and N.Bernberg., Pollution and Physiology of Marine Organisms. 14.Kannan,K.,Fundamentals of Environmental Pollution. 15.Matsumura,F.,1980. Toxicology of Insecticides. Plenum Press, London. 16.Monney, H.A. and M.Goddon,1983. Disturbance and Ecosystems.,Springer Verlag, NewYork. 17.Nebel.,1987.Environmental Sciences.The way world works: II.Ed. Prentice Hall Iunc.,

Englewood,Cliffs, NewJersey. 18.Philips,J.G.1975.Environmental Physiology.BlackwellSci.Publ., 19.Prosser,C.L.(Ed) 1973.Comparative Animal Physiology,/W.B.S.Aunderco., 20.RalphMitchell. 1972. Water Pollution Microbiology, JohnWiley&Sons, INC, NewYork. 21.RobertLewSmith, 1977.ElementsofEcologyand field Biology.,Harper and Row Publ.,New York., London 22.Satake,M.,et.al.,EnvironmentalToxicology 23.Schmiddt,J.G.1975.Environmental Physiology. Adapting of Environment.,III Edition,

Cambridge Univ. Press. 24. Smith, R.L.1980. Ecologyand Field Biology. Harper & Row Publ., New York. 25. Warren, C.E., 1971.BiologyandWaterPollutionControl. W.B. Saunders Co., Philadelphia, USA.

Unit X 1. Andrewartha,H.G.and L.C.Birch1984.The Ecological Web-More on the distribution

and abundance of animals. The University of Chicago Press, Chicago.506p. 2. Anon, 2000.Environmental Laws of India-An Introduction. C.P.R.Environmental Education Centre,Chennai.76p.

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3. Anon2004. IndianWildlifeProtectionAct1972.NatrajPublishers,DehraDun. 104p. 4. Cody, M.L. and J.M. Diamond 1975. Ecology andEvolution of Communities. Harvard UniversityPress.Cambridge.545p. 5. De,A.K. 1996.EnvironmentalChemistry.NewAgeInternational(P)Limited, NewDelhi. 364p. 6. Gaston,K.J.1996.Biodiversity-ABiologyofNumbersandDifference.BlackwellScience, Oxford.396p. 7. Giles,H.1984. Wildlife Management Techniques.NatrajPublishers,DehraDun. 8. Gopal, R.1992.FundamentalsofWildlife Management.JusticeHome. Allahabad.668p. 9. Handa,S.K.1999. PrinciplesofPesticideChemistry.AgrobiosPublishers,Jodhpur.309p. 10.Heyer,W.R.etal1994.Measuring andMonitoringBiologicalDiversity, Standardmethodsfor Amphibians.SmithsonianInstitutionPress.Washington.364p. 11.Huffaker,C.B.andA.P.Gutierrez1999.EcologicalEntomology.JohnWilelyandSons,New

York.756p. 12.InternationalCommissionofZoologicalNomenclature1999.Internationalcodeofzoologic

al nomenclature.4thEdition.InternationalTrustforZoologicalNomenclature,London.306p.

13.Kamrin,M.A. 1997. PesticideProfiles.CRCPress, USA.676p. 14.Kikkawa,J.andD.J.Anderson1986.CommunityEcology:PatternandProcess.Blackwell

ScientificPublications,Oxford.432p. 15.Michael,P.1984.EcologicalMethodsforFieldandLaboratoryInvestigations.TataMcGraw

- HillPublishingCompanyLimited, NewDelhi. 404p. 16.Odum,E.P.1996. FundamentalsofEcology.NatrajPublishers,DehraDun574p. 17.Rodgers,W.A.andH.S.Panwar1988.PlanningaProtectedAreaNetworkinIndia.Wildlife

Instituteo India,DehraDun. 18.Southwood, T. R.E.and P.A. Henderson 2000. Ecological Methods. Blackwell Science.

Oxford.575p.

Unit XI 1.LimnologyCharlesR.GoldmanandAlexanderJ.Horns1983, McGrawHill InternationalBookCo.,NewDelhi.

2.Elementsofecologyand FieldBiology,Robert LewSmith, 1977, Harperand Row Publishers,,NewYork,London

3.EnvironmentalProtection,EmilT.Chanlett, 1973McGrawHillCo.,NewDelhi 4.FieldBiologyand ecologyAllendH BentonandWilliam, EWarner Jr.1976.Tata

McGrawHillPublishingCo.,NewDelhi. 5. ModernconceptsofecologyH.D. Kumar197VikasPublishingHousePvt.Ltd.,NewDelhi. 6.EcologyofFreshwater,AlisonLeadlayBrown1971, HeinemannEducationalBooks

Ltd.,London. 7.IntroductiontoEcology,PapulA.Colinvaux,1978JohnWileyand Sons, Inc.,NewYork. 8.EnvironmentalPollution, Mastumura,M.1972AcademicPress, London 9.SewageBiology, Metcoffand Eddy1970McGrawHillCo.,NewYork. 10.WaterPollutionMicrobiology,RalphMitchell,1972.JohnWiley&Sons. Inc,NewYork,London. 11.AnIntroductiontoFreshwaterOrganisms,A.Tonapi.

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12.Fishand FisheriesofIndiaV.G. Jhingram,1980HindustanPublishingCo.,NewDelhi. Unit XII 1. The ecologyofinsectpopulations intheoryand practice–Clark,L.R.Geiger,P.W. Hughes,

R.D. and Morris, R.F. 2. TheDistributionand abundanceofanimals–Andrewarthan,H.G. and BriohI.C. 3. Recentadvances inEntomologyinIndia – Ed.AnanthakrishnanT.N. 4. BiologicalcontrolofInsectpestsand Weds–Paule.Bach 5. AgriculturalInsectpestsofthetropicsand theircontrol–Hill,D.S. 6. NewTechnologyofpestcontrol– Ed.C.B.Huggaker 7. Pesticidesapplicationmethods–Mathews,G (1979) 8. Ecologicaleffectsofpesticides–Perring,F.H.andMellambyK,(1979) 9. PestManagement:-G.M.Mathews(1984) 10.BasicprinciplesofInsectsuppressionand Management–E.F.Kpipling(1979) 11.Migrationand dispersalofinsectsbyflight–C.G.Johnson 12.InsectEcology–PeterW.Price (1975) 13.GeneticcontrolofInsectpests–G.Davidson(1974) 14.EcologyofPesticides–A.W.A.Brown(1978) 15.Breedingplantsresistanttoinsects– (1980)F.G.MaxR.B.Jennings 16.Introductiontoinsectpest management(1971)R.L.Metcalfe andW.H. Luckman 17.BiologicalInsectSuppression(1977)H.C.Copaland J.W.Mertins 18.InsectPheromones(1972) M.Jacobson 19.Chemicalcontrolofinsectbehaviour(1977)ShoreyH.H. and Kchelvy,J.J. 20.EcologicalmethodswithparticularreferencetothestudyofInsectpopulation– TRE

Southwood(1975) 21.Development and PhysiologyoftheOocyte–Nursecell. Syncytium– TelterW.H. 1975.

AdvancesinInsectPhysiologyVol.II 22.InsectHormones–V.J.A.Novak1975Chamoman&Hall 23.PhysiologyofInsectreproduction–F.EnglemannPergamonPress 24.ComparativeInsectPhysiology.BiochemistryandPharmacology–Vols.1&2&12–1985

Eds.G.A. Kerkut&L.I.GilbertPergamonPress.

Unit XIII 1. Destructive and Useful Insects.TheirHabitsand control, Metcalf,C.L.andFlint,W.P(1967) 2. General and Applied Entomology. Nayyar,K.K., Ananthakrishnan,T.N.and DavidB.V.

(1976) 3. Pest Management,Mathews,G.(1979) 4. Toxicology of insecticides Matsumura(1985) 5. Statistics Work book for Insecticide Toxicology. Regupathy,A.and Dhamu,K.P.(1990) 6. The Scientific Principles of Crop Protection. Martin, H. 7. Neem for the Management of Crops Diseases (Ed). Mariappan,V 8. Neemand Environment,Vol.I &II(Ed) Singh, P.P.Chari, M.S., Raheja, A.K. and

Kraws,W. (1996) 9. Elements of Economic Entomology Vasantharaj David, B. and Kumarasamy T.(1998) 10.Agricultural insect pests of tropics and their control .HillD.S.

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11.New Technology of Pest control. Ed.C.B.Huggaker. 12.Pesticide application method–Mathews,G (1979) 13.Pest Management,G.M. Mathews(1984)

Unit XIV 1. Fisheries research planning and Management in developing countries-

V.R.P.Sinha - InternationalBooksand Periodicalsservices(IBS)-NewDelhi

Unit XV 1.Lodish,Harvey;Berk,Arnold;Zipursky,S.Lawrence;Matsudaira,Paul;Baltimore,David; Darnell, JamesE.2006Molecular Cell Biology,: W.H. Freeman&Co.Publisher,NY

2. BrownT.A., 2009.Genomes.Garland Science Publications, London. 3. Cooper,G.M., 2007The Cell-AMolecular Approach ,Sinauer Associate Publications, Sundarland 4. Priscott et al., 2008. Introduction toMicrobiology. Freeman Publications, USA 5. Trends in Microbiology Trends in Biotechnology series and other related journals area vailableon line. 6. Lesk,A.,2009IntroductiontoBioinformatics.Oxfordpress,UK.