Introduc)on  

Chief  Execu)ve  Officer:  Professor  Gary  Ford  CBE  Chief  Opera)ng  Officer:  Dr  Paul  Durrands  

AHSN  core  purpose  –  health  and  wealth  •  Licensed by NHS England for 5 years to deliver four

objectives: •  Focus on the needs of patients and local populations:

support and work in partnership with commissioners and public health bodies to identify and address unmet health and social care needs, whilst promoting health equality and best practice.

•  Speed up adoption of innovation into practice to improve clinical outcomes and patient experience - support the identification and more rapid uptake and spread of research evidence and innovation at pace and scale to improve patient care and local population health.

•  Build a culture of partnership and collaboration: promote inclusivity, partnership and collaboration to consider and address local, regional and national priorities.

•  Create prosperity through co-development, testing, evaluation and early adoption and spread of new products and services.

The  Oxford  AHSN  •  Our  Vision.  Best  health  for  our  popula.on  and  prosperity  for  our  region  

•  Our  Mission.  We  will  bring  together  universi.es,  industry  and  the  NHS  to  improve  the  health  and  prosperity  of  the  Oxford  region  through  rapid  clinical  innova.on  adop.on  

The  Oxford  AHSN  •  Strategy  and  objec)ves.  Our  strategy  is  to  be  facilita.ve  and  

work  through  our  partners  •  We  will  build  infrastructure  and  support  the  development  of  

people  to  accelerate  innova.on  and  early  adop.on  in  our  NHS  partners  that  improves  health  and  adds  value  

•  This  will  include  funding  clinical  networks  and  developing  teams  for  commercial  development  and  innova.on  adop.on  to  promote  and  accelerate  change  

•  Our  values.  We  will  be  inclusive,  transparent  and  fair  

What  and  where  

http://www.oxfordahsn.org/our-work/wealth-creation/obn-map/ Oxford AHSN Life Sciences map link:

Oxford AHSN – 1 of 15 AHSNs 3.3M population Annual NHS spend circa £5bn NHS employees 65,000 326 GP practices, 2,000 GPs 11 Trusts 12 Clinical Commissioning Groups 4 Local Enterprise Partnerships 12 Councils Major international companies 569 healthcare and life science organisations Complex and varied landscape

Our  health,  university  and  LEP  partners  

New  partnerships  Universities

Life Science Industry

Wealth Creation Clinical Innovation

Adoption

Research & Development

Our  4  programmes  support  the  interfaces  of  

all  the  partners  

Patients and Public

Best Care

AHSNs,  AHSCs  and  the  research  and  innova)on  landscape  

INVENTION EVALUATION ADOPTION DIFFUSION

NIHR Infrastructure BRCs, BRUs, CRFs

NIHR Infrastructure CLAHRCs

AHSCs AHSNs

NHS Patient Care

NHS Patient Care

NIHR Infrastructure

Clinical Research Network

NIHR Programmes

MRC Programmes

Oxford  AHSN  governance  structure  

Programme Office

Oxford AHSN Board – Nigel Keen (Chair), Gary Ford (CEO) and Paul Durrands (COO) and oversight group chairs

AHSN Partnership

Council (annual general meeting open to all)

AHSN Partnership Board

(all NHS CEOs, HEI Leads, LEPs, CCGs, HETV, SCN, ABPI, ABHI, BIVDA) At least two meetings per year)

We welcome new partners Great  Western  Hospitals  NHS  FT  is  working  with  our  clinical  networks,  R&D  and  Clinical  InnovaAon  AdopAon  programmes.  Bedford  Hospital  NHS  Trust  is  working  with  the  Imaging  Network,  has  EBH  Fellowship  and  was  an  OBN/AHSN  Award  winner.  Frimley  Health  is  engaged  in  Best  Care,  Clinical  InnovaAon  AdopAon  programme,  PaAent  Safety  and  the  Partnership  Board.  

Core  team  structure  

CEO  Gary  Ford  

Chair  Nigel  Keen  

COO  Paul  Durrands  

Execu.ve  Assistant  Jo-­‐anne  Harrison  

Programme  Officer  Amy  

Shearman  

Programme  offi

ce  

Comms  support  Val  Tate  

The  Oxford  AHSN  –  4  programmes  1.   Best  Care  programme  

•  Clinical  networks  -­‐  10  AHSN  funded  and  working  with  Thames  Valley  Strategic  Clinical  Networks  

•  Con)nuous  learning  –  working  with  Health  Educa.on  Thames  Valley    •  Fellowships  in  Evidence  Based  Healthcare  

2.   Clinical  Innova)on  Adop)on  programme  –  adop.on  at  scale  of  innova.ons  to  improve  pa.ent  outcomes,  experience  and  safety.  Clinically  led,  working  with  NHS  providers  and  industry  

3.   Research  and  Development  programme  -­‐  work  with  Thames  Valley  and  South  Midlands  Local  CRN,  NIHR,  CLAHRC,  life  science  industry  and  other  research  infrastructure  

4.   Wealth  Crea)on  programme  -­‐  help  the  region  become  the  favoured  loca.on  for  inward  life  science  investment,  life  science  business  crea.on  and  growth  

Best Care The  Oxford  AHSN   is   funding  and   suppor.ng  10  clinical   networks   for   making   improvements   in  health.  We   also  work   closely   with   the   Thames  Valley  Strategic  Clinical  Networks  (SCN)    

1.   Anxiety  and  Depression  2.   Children      3.   Demen)a      4.   Diabetes      5.   Early  interven)on  in  mental  health    6.   Imaging      7.   Maternity      8.   Medicines  op)misa)on    9.   Mental  and  physical  comorbidity      10.  Out  of  Hospital  Care      

Mr   Chand i   Ra tna tunga ,  Associate   Medical   Director   at  Oxford  University  Hospitals  NHS  Trust,   is   the   Senior   Responsible  Office   for   the   Best   Care  Programme.   He   has   been  involved   in   the   Oxford   AHSN  since  June  2012,  working  on  the  d e ve l opmen t   o f   c l i n i c a l  networks,   a   unique   feature   of  the  Oxford  AHSN.    

Best  Care  Programme  Structure  –  Clinical  Networks  Be

st  Care  Programme  

  Anxiety  and  Depression   Children’s   Demen)a   Diabetes   Early  Interven)on  in  

Mental  Health  

Host   Oxford  Health   Oxford  University  Hospitals   Oxford  Health   Oxford  University  

Hospitals   Oxford  Health  

Network  Manager   Ineke  Wolsey   Tim  Gustafson   TBD   Chris  Hille   Sarah  Amani  

Clinical  Lead(s)   Prof  David  Clark   Prof  Andrew  Pollard     Dr  Rupert  McShane    Dr  Katharine  Owen    Dr  Belinda  Lennox  Dr  Mark  Allsopp  

PIDs  (Projects)  

•  Reducing  Unwarranted  Varia.on  

•  Suppor.ng  Local  Service  Innova.on  and  Dissemina.ng  Successes

•  Improving  Immunisa.on  Coverage  

•  Equity  in  Healthcare  Delivery  

•  Research  Facilita.on

•  Reducing  Varia.on  in  Care  

•  Data  Capture  Systems  

•  ΔG™  Nutraceu.cal  

•  Young  People  with  Demen.a

•  Tackling  Varia.on  in  Diabetes  Care  

•  Gesta.onal  Diabetes  Telehealth  

•  Young  Adult  Diabetes  Service    

•  Islet  Cell  Transplanta.on

•  Reducing  Varia.on  in  Care    

•  Common  Assessment    

•  Enhancing  Care  Con.nuity  and  Extending  Model  of  Early  Interven.on    

•  Research  recruitment

Best  Care  Programme  Structure  –  Clinical  Networks  Be

st  Care  Programme  

    Imaging   Maternity   Medicines  Op)misa)on  

Mental  and  physical  Co-­‐Morbidity  

Out  of  Hospital  Care  

Host   Oxford  University  Hospitals  NHS  Trust  

Oxford  University  Hospitals  NHS  Trust  

Oxford  University  Hospitals  NHS  Trust  

Oxford  University  Hospitals  NHS  Trust  

Oxford  University  Hospitals  NHS  Trust  

Network  Manager   Jenni  Lee   Katherine  Edwards   David  Tutcher   Michelle  Acum   Damian  Haywood  

Clinical  Lead(s)   Prof  Fergus  Gleeson    Mr  Lawrence  Impey    Mr  Bhulesh  Vadher     Prof  Mike  Sharpe     Dr  Daniel  Lasserson    

PIDs  (Projects)  

•  Reducing  Unwarranted  Varia.on  

•  Specialist  Opinion  Network  

•  Imaging  Trial  Development  and  Delivery  

•  Early  PET-­‐CT  for  Lung  Cancer  

•  Improving  Foetal  Medicine  care  and  consistency  

•  Maternity  informa.on  sharing  

•  Reducing  Unwarranted  Varia.on  

•  QIPP  and  Waste  Reduc.on  Projects  

•  Providing  Medicines  Informa.on  Knowledge  on  Discharge  

•  Developing  Strategic  Rela.onship  with  Pharmaceu.cal  Industry  Partners  

•  Iden.fying  &  Implemen.ng  Best  Care  Model  

•  Improving  &  Expanding  Out  of  Hospital  Care  Models  for  Acute  Illness  in  Frail  Pa.ents  

Best  Care  Programme  Structure  –  Con)nuous  Learning  Be

st  Care  Programme  

    Fellowships  in  Evidence  Based  Healthcare    

Host   University  of  Oxford  Network  Manager   Ruth  Davis  Clinical  Lead(s)   Prof  Carl  Heneghan    

PIDs  (Projects)  

•  Evidence  Based  Healthcare  MSc  Fellowship  Programme    

Clinical  networks  tackle  varia)on  –  Children’s    •  Report  :  “Varia.on  in  Paediatric  Care  in  the  Thames  Valley”,  Dr  Craig  McDonald.    •  Compared  admission  rates,  day  case  rates  and  mean  length  of  stay  for  5  common  paediatric  

condi.ons  and  revealed  significant  varia.on  within  the  Oxford  AHSN  region.    •  Admission  rates:  between  2.9  and  7.6  fold  varia.on  differences  in  admission  rates  across  the  

region.    •  CCG’s  with  significantly  (>2SD)  above  the  na.onal  average  in  red  •  CCGs  within  2  SD  of  the  na.onal  average  are  highlighted  in  amber  •  CCGs  (<2SD)  below  the  na.onal  average  are  marked  in  green  

    Gastroenteri)s   Bronchioli)s   Asthma   Pneumonia   Fever  /  Sepsis  (0-­‐4)   Fever  /  Sepsis  (5-­‐17)  

Aylesbury  Vale             L0.001)       .025)      Bracknell  and  Ascot                            Chiltern                            Milton  Keynes     High                        Newbury  and  District                         01)  North  &  West  Reading     )   )   )   )   )   )  Oxfordshire     )       )   )   )      Slough     )   )   )   )       )  Reading             )              Windsor,  Ascot  &  Maidenhead             0.001)              Wokingham     )       )       )      

Medicines  control  and  monitoring  with  industry  partners  •  Pilo.ng  prepara.on  for  EU  legisla.on  (expected  Spring  2015)  on  Falsified  Medicines,  with  Aegate  Ltd  and  

Oxford  University  •  Authen.ca.on  of  medicines  at  point  of  dispensing  using  advanced  product  scanning  and  pack  verifica.on  •  Involves  pharmaceu.cal  manufacturers,  wholesalers,  and    community  pharmacies,  hospital  pharmacies  and  

dispensing  doctors  across  Oxfordshire    •  Adding  value  in  the  UK  through  ability  to  reduce  errors  in  dispensing  and  administra.on  processes  •  Collect  data  across  popula.on  on  medicines  consump.on  and  realise  popula.on  based  medicines  

op.misa.on    

Falsified medicines proposed schema

Anxiety  and  Depression  (IAPT)  Clinical  Network  -­‐  engagement  right  across  the  region  Professor  David  Clark   Clinical  Lead,  Anxiety  and  Depression  Network,  Oxford  AHSN  Professor  Shirley  Reynolds   Clinical  Lead,  Anxiety  and  Depression  Network,  Oxford  AHSN  Ineke  Wolsey   Network  Manager,  Anxiety  and  Depression  Network,  Oxford  AHSN  Lord  Richard  Layard   Director  of  Wellbeing  Programme,  London  School  of  Economics  Professor  Gary  Ford  CBE   Chief  Execu.ve  Officer,  Oxford  AHSN  Dr  Mark  Allsop   Consultant  Psychiatrist,  Berkshire  Healthcare  NHS  Founda.on  Trust  

Joint  lead,  Oxford  AHSN  Early  Interven.on  in  Mental  Health  

June  Dent   Clinical  Lead,  Psychological  Therapies  Pathway,  Oxfordshire  Consultant  Clinical  Psychologist  

Judith  Chapman   Clinical  Director    Specialist  Mental  Health  Services  &  Talking  Therapies  (IAPT),  Berkshire  

John  Pimm   Clinical  Lead  -­‐  Buckinghamshire  Psychological  Therapies  Pathway  Consultant  Clinical  Psychologist  

Jon  Olsen   Manager,  IAPT  and  Psychological  Services,  Milton  Keynes  Lorraine  Davies-­‐Smith   Clinical  Lead,  Luton  Wellbeing  Service  

Consultant  Systemic  and  Family  Psychotherapist    

Heather  Salt  

Sarah  Gibbons  

Pamela  Duckerin  

Costas  Lambropoulos  

Bronwen  Taylor  

Consultant  Psychologist,  Oxon  

Psychological  Wellbeing  Prac..oner  Lead  co-­‐ordinator,  Berks  

High  Intensity  Therapist  and  Long  Term  Condi.ons  Lead,  Berks  

High  Intensity  Therapist  and  PPiPCare  Lead,  Bucks  

High  Intensity  Therapist  and  Breath  Well  Lead,  Bucks  Ailsa  Harrison   Pa.ent  Representa.ve  A&D  Network  Board  Member  

Best  Care  Oversight  Group  •  Joe  Harrison,  CEO,  Milton  Keynes  Hospital,  Chair    •  Chandi  Ratnatunga,  Senior  Responsible  Owner  (SRO)    •  Tina  Kenny  Medical  Director,  Buckinghamshire  Healthcare  •  Catherine  Stoddart,  Chief  Nurse,  Oxford  University  Hospitals  •  Helen  McKenzie,  Director  of  Nursing,  Berkshire  Healthcare    •  David  Buckle,  Medical  Director,  NHS  Central  Southern  CSU  •  Graham  Jackson,  Clinical  Chair,  Aylesbury  Vale  CCG  •  Joe  McManners,  Clinical  Chair,  Oxfordshire  CCG  •  Muir  Gray,  Director,  Bejer  Value  Healthcare  •  Jim  Davis,  Professor  of  Sokware  Engineering,  University  of  Oxford  •  Angela  Coulter,  Senior  Research  Scien.st,    HSRU,  University  of  Oxford  •  Nigel  Edwards  CEO,  Nuffield  Trust  •  Nicola  Walsh,  Assistant  Director  Leadership,  King’s  Fund  •  Paul  Durrands  COO,  Oxford  AHSN  •  Will  Pank  Best  Care  Programme  Manager,  Oxford  AHSN  

The  Clinical  Innova.on  Adop.on  (CIA)  programme  has  evaluated  around  200  innova.ons  taking  account  of  poten.al  benefits,  impact  on  pa.ent  experience,  local  priori.es  and  ease  of  implementa.on.  A  final  shortlist  of  ten,  drawn  from  various  sources  including  the  Oxford  AHSN  clinical  networks,  local  providers,  na.onal  awards  and  Na.onal  Ins.tute  for  Health  and  Care  Excellence  (NICE)  Technology  Appraisal  (TA)  recommenda.ons  –  was  approved  by  the  Oxford  AHSN  Board  and  are  being  adopted  across  our  region  in  2014/15.  

 

Clinical Innovation Adoption

Tracey   Marrio3,   Director   of  Clinical   InnovaAon   AdopAon.  Tracey   is   leading   the   Programme  for   the   Oxford   AHSN,   working  closely   with   the   Oxford   AHSN  clinical   networks,   providers,  commissioners   and   suppliers   for  innovaAon  implementaAon.  

Oxford  AHSN  NHS  partners  strategic  priori)es  

0  

2  

4  

6  

8  

10  

12  

14  High  Quality  Care  

Pa)ent  Safety  

Leadership  and  Governance  

Integrated  Care  

Working  in  Networks  

Innova)on  

Financial  Stability  

Pa)ent  Experience  Effec)ve  Workforce  

Develop  Primary  Care  Led  Services  

Develop  Preventa)ve  Care  Community  

Elderly  Care  

Hospital  Avoidance  

Reduce  Mortality  

Long  Term  Condi)ons  Management  

Total  Providers  Total  CCG  

CIA  –  innova)ons  for  14/15  1.  CAUTI  bladder  scanner  –  reduce  urinary  tract  infec)ons  2.  ECG  Monitor    -­‐  moving  care  closer  to  home  

3.  Electronic  blood  transfusion  –  pa)ent  safety  and  waste  reduc)on  4.  Intermijent  pneuma.c  compression  stockings  –  reduce  risk  of  mortality  

5.  SHaRON  (adults  with  ea.ng  disorders)    –  beier  clinical  engagement  and  experience  

6.  NICE  TA  -­‐  Alzheimer's  –  improved  pa)ent  outcome  and  carer  experience  

7.  NICE  TA  -­‐  Rheumatoid  arthri.s  –  improved  pa)ent  outcome  and  experience  

8.  NICE  TA  -­‐  AF,  warfarin,  an.coagulants  -­‐    reduce  risk  of    DVT/Pulmonary  Embolism    

9.  NICE  TA  -­‐  Renal  cancer  -­‐  improved  survival  

10.  Intra  opera.ve  fluid  management  -­‐  pa)ent  safety  and  recovery  

11. Gesta.onal  diabetes  Management  –  pa)ent  experience  and  reduced  clinic  )me  

CIA  Oversight  Group  Role   Name   Title  

Chair   Anne  Eden   CEO  –  Buckinghamshire  Health    

Senior  Responsible  Owner  (SRO)  Best  Care   Chandi  Ratnatunga   Consultant  Cardiothoracic  Surgeon  –  Oxford  University  Hospitals  

CIA  Programme  Director   Tracey  Marrioj   Director  of  Clinical  Innova.on  Adop.on  –  Oxford  AHSN  

Senior  Business  Lead   Paul  Durrands   Chief  Opera.ng  Officer  –  Oxford  AHSN  

Provider  Medical  Director   Brian  Reid   Mr  Brian  Reid  –  Medical  Director  –  Royal  Berkshire  Hospital    

Provider  Director  of  Nursing   Catherine  Stoddart   Director  of  Nursing  –  Oxford  University  Hospitals  

Provider  Director  of  Finance   Alex  Gild   Director  of  Finance  –  Berkshire  Healthcare    

Provider  Procurement  lead   Wayne  Preston   Director  of  Finance  and  Procurement  –  Buckinghamshire  Health    

Provider  Chief  Opera.ng  Officer   Lisa  Glynn   Chief  Opera.ng  Officer  –  Heatherwood  &  Wexham  Park  Hospitals  

Commissioner  Finance  lead   Janet  Meek   Director  of  Finance,  Berkshire  West  CCG  Federa.on  

Academic  Lead  Clinical  Nursing  Prac.ce   Susan  Procter   Clinical  Nursing  Lead,  Buckinghamshire  New  University  

Academic  Lead  Diagnos.cs  &  Primary  Care   Carl  Heneghan   Professor  and  Director  of  Centre  for  Evidence  Based  Medicine,  University  of  Oxford.  Also  Co-­‐Director  Diagnos.c  Evalua.on  Collabora.ve  

Academic  Lead  Innova.on  Adop.on   Clive  Savory   Open  University  –  Communica.ons  &  System  Department    

Academic  Lead  Pa.ent  Safety     Charles  Vincent   Professor  of  Psychology  –  Department  of  Experimental  Psychology  

Oxford  AHSN  Medicines  Op.misa.on  Network  Lead      

Bhulesh  Vadher   Chief  Pharmacist  –  Oxford  University  Hospitals  

Senior  Lecturer  Marke.ng  and  Course  –  Leader  PR  &  MarCom  

Bill  Nichols   Director  –  Centre  for  Health  Communica.ons  Research  Buckinghamshire  New  University  

CIA  Case  study  -­‐  Gesta)onal  Diabetes  The Health Need and Benefits •  Increasing numbers of women with 3rd

Trimester Gestational Diabetes requiring clinical monitoring

Benefits •  Assists with patient self management •  Remote clinical monitoring with alerts •  Regular opportunity to communicate with

patient •  Reduction in unnecessary clinic visits so

increased capacity •  Further research underway on impact on

difficult births and birth defects. Developed as a collaboration between OUH (Lucy McKillop) and Institute of Biomedical Engineering at the University of Oxford (Lionel Tarassenko)

Trusts 2014/15 2015/16Ox  Uni  Hosp !Royal  Berks  Hosp !Milton  Keynes !Frimley  Health UnderwayBucks  Healthcare PlannedGreat  Western PlannedBedford Planned

Roll  Out  Completed  and  Planned

Poten.al  savings  to  the  NHS  in  Oxford  AHSN  region  of  £700k  full  adop.on  of  technology  

Project  Objec)ves:  1.   Increase  the  relevant  adop)on  of  Intra  Opera)ve  Fluid  Management  Technology  across  

the  region  2.   Understand  the  barriers  to  adop)on  from  perspec)ve  of  NHS  Providers,  NHS  

Commissioners,  Industry  3.   Design  and  develop  a  useful  tool  that  providers  and  commissioners  can  use  for  business  

planning,  service  development  and  contract  management  4.   Provide  feedback  to  NHS  England  to  inform  na)onal  policy  

Es)mated  47,000  people  in  Oxford  AHSN  region  could  benefit  from  full  

implementa)on  of  IOFM  

technology  

Expected  Pa)ent  Outcomes:    

Providing  senior  doctors  and  nurses  informa)on  to  assist  clinical  prac)ce  and  departmental  management,  based  on  robust  evidence.  The  expected  pa)ent  outcomes  are:  •  Reduce  rate  of  re-­‐admission  and  re-­‐opera)on  •  Fewer  post  opera)ve  complica)ons  •  Reduce  emergency  admissions  into  intensive  care  amer  surgery  •  Low  risk  of  cardiac  complica)ons  minimally  or  non-­‐invasive  monitoring  •  Reduce  risk  of  catheter  (CVP,  arterial,  PAC)  related  infec)on  •  Reduce  length  of  hospital  stay,  pa)ents  are  ‘fit  for  discharge  sooner’      

Par)cipa)ng:      Royal  Berkshire  Hospital,  Frimley  Health  ,  Bucks  Healthcare,  Milton  

Keynes  Hospital,  Bedford  Hospital,  Oxford  

University  Hospitals,  Great  Western  Hospitals,  

Central  Manchester  Hospitals  

Poten.al  savings  to  the  NHS  in  Oxford  AHSN  £24.3M  full  adop.on  of  technology  

April  14  

• Project  Selected  and  supported  by  RIF  Fund  

May  

• Set  up  collabora.on  with  NHS  Benchmarking  Network  to  delivery  the  project  

June  

• Project  launch  across  the  Oxford  AHSN  region.    NHS  England  agree  to  par.cipate  in  project.  

Sept  

• Clinical  Regional  Workshop  hosted  to  design  benchmarking  dataset  

Oct  

• Suppliers  engaged  to  understand  barriers  to  adop.on  

Nov  -­‐Dec  

• IOFM  Benchmarking  Dataset  launched  with  qualita.ve  survey  

March  

• Presen.ng  ini.al  findings  at  the  Na.onal  Theatre  Benchmarking  Conference  in  London  

April  15  

• Na.onal  rollout  of  IOFM  project  as  part  of  the  Na.onal  Theatre  Benchmarking  Project  

Intra  Opera)ve  Fluid  Management    Clinical  Leader  –  Dr  Emmanuel  Umerah,  Frimley  Health    

Prof  Gary  A  Ford  CBE  is  Chief  ExecuAve  Officer  of  the  Oxford  AHSN.  Gary   has   led   the   adopAon  of  innovaAon   in   stroke   care   for   many   years.   He  remains   a   pracAsing   clinician   as   a   Consultant  Stroke   Physician   at   Oxford   University   Hospitals  NHS   Trust.   He   is   also   Director   of   the   NaAonal  InsAtute   for   Health   Research   (NIHR)   Stroke  Research  Network.  

•  Brings  together  leads  from  Universi.es  and  NHS  partners  

•  NHS  partners  to  each  develop  R&D  strategies    

•  Grow  commercial  research  base  and  income  across  the  NHS  Trusts  

•  Close  links  with  Clinical  Research  Network  (LCRN)  and  the  Collabora.on  for  Leadership  in  Applied  Health  Research  and  Care  (CLAHRC)  

•  Cross  working  with  the  Oxford  Academic  Health  Science  Centre  (AHSC)  –  one  of  6  leaders  in  research

Research & Development

Big  Data:  Delivering  the  Digital  Medicine  Revolu.on  

Building  Novel  NHS,  University  and  Industry  Rela.onships  

Modula.ng  Immune  

Response  for  Pa.ent  Benefit  

Managing  the  Epidemic  of  Chronic  Disease  

Emerging  Infec.ons  &  An.microbial  Resistance  

Cogni.ve  Health:  

Maintaining  Cogni.ve  Func.on  in  Health  and  Disease  

Oxford  Academic  Health  Science  

Centre    -­‐    world  leading  research  in  

healthcare  and  life  sciences  

R  &  D  Oversight  Group  University Research  lead/alternate Chairman,  Oxford  University  Hospitals Sir  Jonathan  Michael University  of  Oxford Professor  Alastair  Buchan University  of  Reading Dr  Ben  Whalley   Buckinghamshire  New  University Professor  Susan  Procter The  Open  University Dr  Nacho  Romero  /  Dr  Claire  Turner The  University  of  West  London Professor  Heather  Loveday/Dr  Jennie  Wilson Oxford  Brookes  University Professor  Linda  King  (Mary  Boulton/Helen  Dawes)  University  of  Buckingham Professor  Mike  Cawthorne University  of  Bedfordshire Professor  Mike  Fisher Cranfield  University TBC Oxford  University  Hospitals Prof  Keith  Channon Oxford  Health Prof  John  Geddes Berkshire  Healthcare Dr  Jus.n  Wilson Heatherwood  and  Wexham  Park Dr  Rob  Loveland Royal  Berkshire Dr  Atul  Kapila South  Central  Ambulance  Service Mr  Will  Hancock/John  Black Central  and  North  West  London Dr  Alex  Lewis Milton  Keynes Mr  Mar.n  Wetherill Great  Western Dr  David  Collins Buckinghamshire  Healthcare Dr  Helen  Eagleton Bedford  Hospital Dr  Coleje  Marshall Southern  Health Dr  Helen  McCormack Health  Educa)on  Thames  Valley/Oxford  University  Clinical  Academic  Graduate  School

Professor  Chris  Pugh

South  Midland  and  Thames  Valley  Clinical  Research  Network Dr  Belinda  Lennox/Dr  Andrew  Protheroe Collabora)on  for  Leadership  in  Applied  Health  Research Professor  Richard  Hobbs/Dr  Belinda  Lennox

Wealth Creation

Dr   Nick   Sco3-­‐Ram   MBE,   Director   of   Commercial   Development,   has   over   25  years   experience   in   commercial   and   business   development   in   the   life   sciences  sector.  Nick  was  awarded  the  MBE  for  services  to  biotechnology  in  2001.  

The  Wealth   Crea.on   Programme  will   help   the   region   become   the  favoured   loca.on   for   life   science   investment,   life   science   business  crea.on  and  growth,  helping  the  NHS  –  through  the  Oxford  AHSN’s  Clinical   Innova.on  Adop.on  programme  and  Clinical  Networks  –  to  accelerate   the   adop.on   of   proven   innova.ons   which   will   bring  significant  benefit  to  pa.ents.  

                         The  Oxford  AHSN  wealth  crea.on  strategy  is                             for,   and   on   behalf   of,   our   member                              organisa.ons  –  the  NHS,  Local  Enterprise                            Partnerships  (LEPs),  Universi.es  and  industry                            –  and  the  popula.on  who  all  share  an  interest                            in  economic  growth  across  the  region.  

Oxford  AHSN  Wealth  Crea)on  

Types of Medical Innovation Any new product or service that delivers benefit to patients

•  Pharmaceuticals – New drugs or new uses for established drugs •  Vaccines •  ATMP (Advanced Therapy Medicinal Products) – Gene or cell therapies •  Tissue engineered products and regenerative medicine •  Surgical innovations •  Medical diagnostics and devices •  Information Technology, medical informatics, mHealth and eHealth •  Clinical decision making and support including IT tools to support compliance with best practice •  Healthcare delivery, management and administration •  Health promotion & disease prevention and patient driven wellness (public health)

Outbound Innovation Helping to ensure that great ideas from the NHS, universities and industry are converted into products and services

that create value for patients within and beyond our region

Inbound Innovation Informing the NHS about high value

innovations and enabling staff to make full use of them to improve outcomes

and experiences of patients

Wealth  crea)on  –  key  priori)es  •  Suppor)ng  companies  along  the  adop)on  pathway  

•  Clear  innova.on  pathways  from  origina.on  to  adop.on  highligh.ng  health  benefits  and  alignment  with  NHS  needs  

•  Benefits  to  large  and  small  businesses  

•  Suppor)ng  investment  into  the  region  •  Regional  investment  fund  •  Grant  support  –  SBRI,  Horizon  2020,  Innovate  UK  

•  Building  a  culture  of  innova)on  in  the  NHS  •  Entrepreneurs  boot  camp  •  Challenge  2023  

•  Building  long-­‐term  partnerships  with  businesses  &  other  organisa)ons  •  SMEs  &  large  companies  

Over 40 projects in progress

Suppor)ng  companies  along  the  adop)on  pathway  •  14  projects  with  companies  

•  Large  companies  •  Implementa.on  study  for  BNP  in  ambulatory  clinic  

•  Pathway  analysis  of  GBS  test  in  neonatal  clinics  

•  SMEs  •  £1  million  SBRI  award  in  POC  fluoropolymer  

capillary  film  plavorm  for  acute  coronary  syndrome  

•  Pilot  study  in  local  Trusts  for  IU  technology  audit  

•  SBRI  award  winning  plavorm  for  vital  signs  monitoring  in  pa.ents  

•  TTOs  •  Review  of  diagnos.cs  porvolio  for  clinical/NHS  

opportuni.es  

Building  investment  opportuni)es  across  the  region  •  15  projects  across  the  region  

•  Regional  Investment  Fund  •  GE  Healthcare  Finnamore    

•  The  Alumni  Summit  

•  Oxford  Smart  City  

•  Buckinghamshire  Life  Sciences  Business  Plan  

•  Structural  Genomics  Consor)um  •  Spin-­‐out  opportuni.es  –  inflamma.on      

Oxford AHSN | October 2014 Copyright © 1992-2014 GE Healthcare Finnamore

21

Section 3: Structure of the innovation and investment system

Innovation Investment

Fund (IIF)

Fund Manager

Innovation Investment Company

(IIC)

NHS England

Corporate(Sponsorship(

Oxford(AHSN(

Sponsorship/(Funding(

LP(Investor(

LP(AHSN(

Due(Diligence(And(Negotiation(

Venture(Board(Representation(

Investment(Committee(

Investor(Relations(

��������(Funds(

Opportunity(Screening(

Post(investment(Venture(Management(

Support(

PreFNICE(Assessment(Trial(Design(Support(

NHS(Procurement(&(Deployment(Planning(

Opportunity(Origination(

NHS(Asset(and(Capability(Matching((

Oxford AHSN

Innovation and Commercialisation Funding

Corporate Sponsor: � Board(membership(� Technical(advisory(� Pipeline(review(

Wealth  crea)on  –  Apps  and  e-­‐health  lab  •  Commissioned  App  Development  Roadmap  •  Oxford  e-­‐health  Lab  –  mul.-­‐partner  coordina.ng  

hub  for  e-­‐health  ac.vity  and  accelera.on  of  innova.on  and  implementa.on  

•  Local  App  examples:  •  AED  Locator  (find  a  defibrillator)  •  Foodswitch  –  calorie  and  salt  control  •  Monster  Manor  –  blood  sugar  control  for  children  with  

Type  1  Diabetes  

   

Projects  with  deliverables  by  March  2015  •  Capillary  Film  Technology  

•  Helped  company  develop  programme  and  secure  £1  million  SBRI  award  

•  Intelligent  Ultrasound  •  Pilot  study  for  quality  assessment  of  IU  

images  

•  Innova)on  Adop)on  Workshop  •  Pilot  workshop  for  industry  

•  Structural  Genomics  Consor)um    •  Business  plan  for  spin  out  in    

•  New  pre-­‐compe))ve  pathways  for  drug  discovery  

•  Open  access  IP  workshop  

•  Precision  Medicine  Catapult  •  AHSN  lead  on  proposals  for  loca.ng  in  

Oxford  region  

•  Forma)on  of  Oxford  AHSN  Diagnos)cs  Advisory  Council  

•  Focus  for  industry  interac.ons  with  NHS  –  Dx  companies  in  region  comprise  over  80%  global  market  share  

•  Entrepreneurs  Boot  Camp  •  Course  for  clinicians  and  healthcare  workers  

•  Sustainability  and  carbon  reduc)on  benchmarking  programme  

•  Provide  baseline  for  feasibility  studies  for  6  centres  to  be  taken  forward    

•  BIVDA  Point  of  Care  Working  Group  •  Hosted  mee.ng  on  commissioning,  

Abingdon  EMU  &  OUH  clinical  diagnos.cs    

Wealth  Crea)on  Oversight  Group  

Wealth  Crea.on  Oversight  Group  

Berkshire  Working  Group  for  Wealth  

Crea.on  

Buckinghamshire  Working  Group  for  Wealth  Crea.on  

Oxfordshire  Working  Group  for  Wealth  Crea.on  

Chairman Dr Nick Edwards – MedInnovate

Professor Chas Bountra – SGC John Collins – CIMIT Martin Hunt – i4i

Martino Picardo – SBC Bruce Potter – Blake Morgan Nigel Tipple – Oxfordshire LEP

Oxford  AHSN  –  3  themes  •  Informa.cs  •  Pa.ent  and  Public  Involvement,  Engagement  and  Experience  •  Pa.ent  Safety  

Informatics Mike  Denis,  Director  of   Informa.on  Strategy  and  Governance,  has  a  dual   role  across   the  Oxford  AHSN  and  Oxford  AHSC  and  provides   strategic   leadership   in   linking   core   business   goals  through   informa.cs   and   technology   innova.on,   whilst  providing  cri.cal   contribu.on  to   the  Oxford  AHSN  and  Oxford  AHSC  partners’  strategies    Informa.cs  is  a  cross-­‐cuxng  theme,  linking  core  business  goals  through   technology   innova.on,   both  within   the  Oxford   AHSN  and  with  partner  organisa.ons    Informa.cs   supports   data   analysis   requirements   and   develop  appropriate  Informa.on  Governance  arrangements  to  facilitate  data   sharing   and   exchange.   We   help   to   facilitate   pa.ent  recruitment   to   research   studies   and   clinical   trials   and   extend  programme   research   databases   across   organisa.ons   in  primary,  community  and  acute  services  

Mike   Den is ,   D i rector   o f  InformaAon   Strategy,   has   over  26  years  experience  working   in  NHS   health   informaAcs.   He  previously  held  a  similar  role  at  t h e   S o u t h   L o n d o n   a n d  Maudsley   NHS   FoundaAon  Trust.  

Informa)cs  •  A  cross  cuxng  theme  of  the  AHSN  •  Exploi.ng  the  value  of  data  for  service  improvement  and  

research  •  A  hybrid  model  for  Informa.cs  

Delivery  -­‐  January  2015  In  collabora.on  with:  

Informa)cs  Oversight  Group  Aiendees   Organisa)on  

Stuart  Bell,  Chairman   Chief  Execu.ve,  Oxford  Health  NHS  FT  

Chris  Bunch   Consultant  Physician  and  Caldicoj  Guardian,  Oxford  University  Hospitals  

Michael  Seres   Pa.ent  representa.ve  

Gary  Ford   Chief  Execu.ve,  Oxford  AHSN  

Paul  Durrands   Chief  Opera.ng  Officer,  Oxford  AHSN  

Caroline  Hargrove   McClaren  

Paul  King   Microsok  

Simon  O’Shaughnessy   Novo  Nordisk  

Paul  Lindley-­‐Scoj   Open  University  

Scoj  Pejy   Vodafone  

Patient and Public Involvement, Engagement and Experience (PPIEE)

Dr   Sian   Rees   is   the   lead   for   PaAent   and  Public   Involvement,   Engagement   and  Experience,  working  with  colleagues  in  Trusts  across   the   Oxford   AHSN,   and   the   NHS  England   Area   Team,   Health   EducaAon  Thames  Valley  and  the  CLAHRC.  In  parAcular,  she  will   support   this   area  of  acAvity   in   each  of  the  developing  clinical  networks.  

The  Oxford  AHSN  is  working  to  embed  partnership  with  pa.ents  and  the  public  across  its  work  programmes.  Each  of  the  clinical  networks  is  developing  plans  for  PPIEE.  The  PPIEE  Theme  is  a  joint  produc.on  with  the  Thames  Valley  Local  Area  team  and  Strategic  Clinical  Networks  

What  do  we  mean  by  involvement?  How   pa.ents   and   the   public   will   be   involved   in   the   structures   and  processes   of   the   work   i.e.   though   mechanisms   such   as   governance,  priority  sexng,  teaching  and  educa.on,   iden.fica.on  of   the  need  for  innova.on,  assessment  of  technologies.  What  do  we  mean  by  engagement?  How  pa.ents  and  their  carers  will  be  supported  to  be  ac.ve  par.cipants  in  their  own  care  through  approaches    such    as  personalised  care  planning  and  shared  decision-­‐making.  What  do  we  mean  by  experience?  How  the  subjec.ve  experience  of  pa.ents  is  captured    and  u.lised  for  quality  improvement.  

Patient Safety

Professor   Charles   Vincent  leads   the   PaDent   Safety  CollaboraDve,   launched   in  October  2014.    Charles  trained  as   a   clinical   psychologist   and  has  worked   in   the  field  of   the  causes   of   harm   to   paDents  and   the   consequences   for  paDents   and   staff   for   many  years.  

The  Pa.ent  Safety  Collabora.ve  (PSC)  was  launched  in  October  2014  –  part  of  a  network  of  15  covering  England.  It  will  focus  ini.ally  on  a  small  number  of  clinical  programmes  but  also  act  as  an  umbrella  and  coordina.ng  centre  for  the  many  important  pa.ent  safety  ini.a.ves  –  both  prac.ce  and  research  –  within  Berkshire,  Buckinghamshire,  Oxfordshire  and  Bedford.  The  principal  aims  of  the  PSC  are  to:  •  Develop  safety  from  its  present  narrow  focus  on  hospital  medicine  to  

embrace  the  en.re  pa.ent  pathway  •  Develop  and  sustain  clinical  safety  improvement  programmes  within  the  

Oxford  AHSN  •  Develop  ini.a.ves  to  build  safer  clinical  systems  across  the  Oxford  AHSN    •  Collaborate  and  support  sister  safety  programmes  both  na.onally  and  

interna.onally.  Early  priori.es  include  the  ac.ve  engagement  of  pa.ents  and  carers;  the  development  of  a  safety  informa.on  system,  the  establishment  and  support  of  programmes  on  acute  kidney  injury,  medica)on  safety,  pressure  ulcers  and  safety  in  mental  health  and  developing  capacity  and  capability  in  leadership  for  safety  improvement.  •  PSC  has  appointed  Jill  Bailey  as  Head  of  Pa.ent  Safety      

Pa)ent  Safety  Academy  •  The  work  of  the  Pa.ent  Safety  Academy,  led  by  Co-­‐Directors,  Professor  Peter  McCulloch  and  Dr  Helen  Higham,  focuses  on:  •  Human  factors  training  •  Training  for  Surgical  teams    •  Development  of  Programmes  in  Mental  Health  &  Primary  Care  

•  Training  for  Trust  Management  and  Boards      

Pa)ent  Safety  Oversight  Group  •  Plans  are  being  developed  for  the  Oversight  Group  for  pa.ent  safety  –  this  will  include  stakeholders  from  across  the  Oxford  AHSN  

Contact  details:  Megan  Turmezei  Director  of  Corporate  Affairs  Oxford  AHSN  The  Magdalen  Centre  Robert  Robinson  Avenue  OXFORD  SCIENCE  PARK    OX4  4GA  Megan.turmezei@oxfordahsn.org    T:  01865  784958  M:  07837  401519  www.Oxfordahsn.org  

 

Newsleier:  http://www.oxfordahsn.org/news-and-events/network-newsletters/

Annual report: http://www.oxfordahsn.org/wp-content/uploads/2014/06/Oxford_AHSN_Annual_Report_2014.pdf