2/5/15Objective: How does DNA replication occur?

Do Now:http://www.youtube.com/watch?v=qy8dk5iS1f0

. Write the missing strand:ACTTGCTG

Template

DNA Replication• DNA replication: DNA makes a copy of itself

What does “to replicate” mean?If you start with one strand of DNA, how many strands will you end up with?

When• During what process does DNA replication

occur?

This occurs during cell division (mitosis)– Regeneration– Growth– Repair

DNA as a Template

Template Strand: Original strand of DNAComplementary Strand: New strand of DNA

ATTCGGTA

Template Strand

-T-A-A-G-C-C-A-T

Complimentary Strand

A closer look at DNA replication…

ATATCGCGCGCGCGCGCGCGTATA

A TA TC GC GC GC GC GC GC GC GT AT A

ATATCGCGCGCGCGCGCGCGTATA

ATATCGCGCGCGCGCGCGCGTATA

Recall…What are the 2

functions of enzymes?

DNA Helicase: An enzyme that “unwinds” or “unzips” the DNA strand

Recall…What are the 2

functions of enzymes?

DNA Polymerase: An enzyme that attaches the complimentary base pairs to the template strand

DNA Simulation

ATCTG

www.youtube.com/watch?v=rpwjZX_z5rg

http://www.youtube.com/watch?v=hfZ8o9D1tus

Turn and Talk

• With the person sitting next to you. In your notesheet under “How DNA replication occurs” write the steps of DNA replication, remembering what we did in the simulation to help you.

Summary

• Describe how DNA is replicated