23rd European Conference on

Biomaterials 2010

(ESB 2010)

Tampere, Finland

11-15 September 2010

ISBN: 978-1-61782-086-1

TABLE OF CONTENTS

High Resolution MRI to Localize Non-Labeled Cells on 3D Scaffolds I

A. Abarrategi, D. Castejon, M. Fernandez-Valle, A. Civantos, C. Moreno-Vicente, V. Ramos, J. Sanz-Casado, F.

Martinez-Vazquez, P. Miranda, J. Lopez-Lacomba

Biological Performance ofReactive Calcium Phosphate Filler - Containing Fast Photo-curing, Surface

- Degrading, Polymeric Bone Adhesives 2

E. Abou Neel, P. Revell, V. Salih, A. Young

Improved Cell Response to High Calcium Phosphate Glasses Co-doped with Titanium Dioxide 3

E. Abou Neel, W. Chrzanowski, G. Georgiou, M. Dalby, J, Knowies

Aligned Collagen Matrices Direct Neuronal Growth and Protect Against Inhibitory MyelinComponents 4

M. Abu-Rub, A, Knight, D. Zeugolis, S. McMahon, A. Windebank, A. Pandit

Composite "Injectable Needles" for the Administration ofHepatitis B Vaccine 5

N. Acosta, R. Carrodeguas, S. Padilla, R. Alloza, A. Garcia de Castro

Thermoluminescence As an Experimental Tool Towards the Characterization of Bioactive Materials:

The Case of 58S Bioactive Glass 6

D. Afouxenidis, G. Polymeris, O. Goudouri, E. Kontonasaki, X. Chatzistavrou, N. Tsirliganis, K. Paraskevopoulos,G. Kitis

pH- Responsive Multilayer Thin Films as an Effective Tool to Control Cellular Behaviour 7

N. Aggarwal, T. Groth

A Calcium Phosphate Bioactive Glass Composite Promotes Angiogenesis Through Biochemical and

Mechanical Cues in BM-derived Endothelial Progenitors 8

A. Aguirre, A. Gonzalez, L. Marquez, M. Navarro, 0. Castano, J. Planell, E. EngelRelease ofRifampicin from Composites of Lactide Based Copolymers and TCP 9

N. Ahola, M- Veiranto, M. Kellomaki

Direct Detection ofModel Target MicroRNA Using a DMAEMA-EGDMA Dendritic Polymer DNA

Probe Complex for Clinical Applications ] 0

A. Aied, B. Glynn, O. Carroll, W. Wang

A Novel Calcium Phosphate-Calcium Silicate Composite 12

M. Alkhraisat, J. Aparicio, A. Ewald, C. Rueda, L. Blanco, U. Gbureck, E. Cabarcos

Silicon Release and Osteoblast Response to a Novel Calcium Phosphate-calcium Silicate Composite 13

M. Alkhraisat, J. Aparicio, A. Ewald, C. Rueda, L. Blanco, U. Gbureck, E. Cabarcos

In Vivo Testing ofa Biodegradable Woven Fabric Made of 1-98 Bioactive Glass Fibers and PLGA80 in

a Rabbit Model of Bone Graft Fixation 14

J, Aim, J. Frantzen, N. Moritz, P. Lankinen, M. Tukiainen, M. Kellomaki, H. Aro

Neurite Outgrowth on PCL/Gelatin Electrospun Scaffolds 15

M. Alvarez-Perez, V. Guarino, V. Cirilh, L. Ambrosio

Surface Grafting ofa Thermoplastic Polyurethane with Methacrylic Acid by Previous Plasma Surface

activation and by Ultraviolet Irradiation to Reduce Cell Adhesion 16

P. Alves, S. Pinto, J-P. Kaiser, A. Bruinink, H. deSousa, M. Gil

Hydroxyapatite Foams Prepared by Gel Casting Method 17

A. Aminian, Z, Tahmasebi-Birgani, A. Farzadi, M. Solati-Hashjin

Development ofa Novel Light-Emitting Photosensitive Technique for the Isolation and Purification of

Viable Cell Populations 18

K. Andrews, J. Hunt

Synthesis of Composite Elastic Hydrogels Using Dense Gas C02 19

N. Annabi, S. Mithieux, A. Falhi, C. Ji, A. Weiss, S. Dehghani

Developments in Tissue Engineering 20

T. Annala

Development ofChitosan/y-Polyglutamic Acid Polyelectrolyte Complexes for Tissue Regeneration 21

J. Antunes, A. Pereira, F. Ferreira da Silva, R, Goncalves, M. Barbosa

Evaluation of Thin Carbon Fiber Web as a Scaffold for Bone Regeneration 22

K. Aoki, K. Hara, Y. Usui, M. Shimizu, N. Ogiwara, N. Ishigaki, K, Nakamura, H. Kato

A Potential Switch to Modulate Drug Release from Cement Systems: The Case of Vancomycin 23

J. Aparicio, M. Alkhraisat, C. Rueda, L. Blanco, U. Gbureck, E. Cabarcos

Fixation ofAnkle Syndesmosis by Antibiotic Releasing Bioabsorbable Screw: A Randomized RSA

Trial 24

H. Aro, T, Makinen, T. Immonen, S. Timlin, N. Moritz, M. Veiranto, P. Tormala

Funtionalized Ti02 Nanoparticles: A New Approach to Prepare Nanostructured Materials 25

E, Arturoni, D. Pasqui, A. Atrei, G. Giani, R. Barbucci

Enhancement of Calcium Nodule Production by Osteoblasts 26

H. Aydin, B. Hu, A. El Haj, Y. Yang

3D Shape Analysis of Filler Particles in the Self-reinforced Polylactide Composites 27

D. Aydogan, M. Hannula, T. Niemela, M. Kellomaki, J. Hyttinen

Mechanical Characterization of a Porous pH-stabilized Composite Material Consisting of Poly(D,L-lactide), Calcium Carbonate, and Gentamicin 28

S. Backhaus, T. Annen, M. Epple

Biotinylated Nanocomposite Microspheres: A Novel Cell Delivery Vehicle for Bone Tissue

Engineering Applications 29

S. Bagheri-Khoulenjani, H. Mirzadeh, M. Khosroshahi, M. ShokrgozarBiodegradable Polymer-based Scaffolds for Meniscus Tissue Engineering Constructs 31

G. Bahcecioglu, A. Ndreu, N. Hasirci, V. Hasirci

Molecularly Imprinted Scaffolds For Tissue Growth Technology 32

N. Barbani, E. Rosellini, C. Cristallini, G. Ciardelli, M. Gagliardi, P. Giusti

Experimental Study of Wear between Bone and Various Prosthetic Materials 33

A. Barbas, A. Bonnet, P. Lipinski, S. Philippon

Collagen- Poly (vinyl-co-acrolein) Hydrogel: Study of Cytotoxicity of Bovine Pericardium 34J. Barros, F. Filippin-Monteiro, A. Carnpa, R. Pitombo, B. Polokiewicz

Monitoring the Foreign Body Reaction using GFP-Macrophages and a Multispectral Acquisition and

Analysis System 35

/. Bartsch, F. Wine

The Investigations of Carbon Coatings Intended for Tools Used in Bone Surgery 36

M. Basiaga, Z. Puszenda

45S5 Bioglass® - Derived Shell Scaffolds for Bone Tissue Regeneration and Repair 37D. Bellucci, V. Cannillo, A. Sola

Grafting of Bioactive Polymer on Alloy Titanium Implant for the Prevention of Bacterial Infections 38

/. Aissa, G. Helary, V. MigonneyIn Vitro-investigations ofCell Behavior Inside a 3D-modcl System 40

C. Bergemann, F. Kunz, E-D. Klmkenberg, P. Elter, U. Beck, R. Bader, B. Nebe

Non-Thermal Rapid Manufacturing of Bone Substitutes Using Biodegradable Cements 41

C. Bergmann, T. Welting, J, Arts, L. Van Rhijn, N. Guldemond, B. VanDe Vorst, R. Telle, M, Lindner, K. Koczur,

H. Fischer

3D Investigation ofBone Formation Around Biofunctionalised Titanium Implants in an OsteoporoticRat Model 42

R. Bernhardt, S. Rehberg, O. Zierau, S. Rammelt, F. Beckmann, G. Volmer, D. Scharnweber

Treatment of MC3T3 Prc-Osteoblasts With Anatasc Titanium Dioxide Nanoparticles Induces The

Secretion ofThe Bone-Resorption Factor IL6 43M. Bernier, K. El Kirat, M. Vayssade

Bioactive Materials and Interfaces for Improved Medical Implants 44

S. Best

Physical and Electrochemical Characterization of Regular Microstructured Titanium Surfaces and

Their Influence on Cell Morphology 45

K. Biala, R. Lange, S. Stahlke, J. Nebe, U. Beck

Assessment ofBone Ingrowth Potential of E-beam Produced Surface Topographies with a Biomimetic

Coating 46

J. Biemond, G. Hannink, N. Verdonschot, P. Buma

Comparison of BMP-2 and -4: Immobilisation and Release from Different Mineralized and Non-

mincralizcd Coatings 47

S. Bierbaum, S. Roessler, H. Worch, D. Scharnweber

Nanoporous Silicon Materials In Drug Delivery Applications 48

L. Bimbo, M. Sarparanta, J. Salonen, J. Riikonen, E. Makila, A. Airaksinen, V-P. Lento, JouniHirvonen, H. Santos

Focal Adhesion and Stretching Mechanical Stress: Translocation of Cytoskeletal and SignalingMolecules 49

F. Boccafoschi, C. Mosca, M. Bosetti, B. Burlando, M. Cannas

Innovations in Medical Image Processing for the Design of Custom Implants and Surgical Guides 50

E. Boelen, D, Willems

Aqueous Impregnation ofPorous (J-Tricalcium Phosphate Scaffolds 51

M. Bohner, C. Stahli, M. Bashoor-Zadeh, N. Doebelin, G. Baroud

Oral Large Bone Defects - The Suitability of a New Biomaterial Combination 52E. Bono, C. Mauth, A. Molenberg, H. Farine, M. Dard, V. Grqf-Hausner

FEM Experimental Study on Dental Resins for Complete Dentures 53C. Bortun, A. Cernescu, B. Ghiban, N. Four, N. Ghiban

Relative Humidity and Electrospinning: Control the First to Succeed in the Second 54D. Bolequim, J. Borges, C. Henriques, J. Silva

Development of a Multifunctional Biomaterial: Bone Graft and Drug Delivery Matrix 55F. Braga, C. Meira, G. Prado, A. Thomazini, A. Da Silva

Use of M1G3® Bioceramic Mattress Liner to Patients with Post-Poliomyelitis Syndrome (PPS) andCold Intolerance 56

F. Braga, T. Silva, A. Oliveira

Sulphonate Based Hydrogel for Nucleus Pulposus Repair 57J. Bramhill, B. Tighe, D. Campbel, F. Lydon, J. Urban, S. Roberts, S. Sivan

The Effect of Microstructured Surfaces on Endothelial Cell Response to Laminar Shear Stress 58A. Brown, B. Meenan, G. Burke

Hollow Collagen Nanospheres as a Resevoir System: pDNA and Polyplex Encapsulation and Release 59S. Browne, G. Fonlana, A. Mathew, A. Pandit

Influence of Differently Nanostructured Diamond Surfaces on Formation ofAdhesion Apparatus of

Osteoblastic Cells (SAOS-2) 60

A, Broz, 0. Babchenko, A. Kromka, M. Kalbacova

Bioenginecred Bone Grafts 6]

B. Buranawal, S. Deb, J. Suwanprateeb, R. Palmer, L. Di Silvio

New Sol-gel Coatings for Dental Applications 62L. Buruaga, G. Goikoetxeaundia, M. Juan, M. Hernandez, M. Gurruchaga, I. Goni, J. Suay

Surface Modification of Polyurethane with Hydrogel Coatings 63

B. Butruk, M. Trzaskowski, T, Ciach

Controlled Degradation of Bioresorbable Polymers via E-Beam Radiation 64

M. Cairns, A. Sykes, G, Dickson, J. Orr, D. Farrar, A. Dumbo, F. Buchanan

The Release ofHeparan Sulfate/FGF-2 Complex by a Polyelectrolyte Scaffold induces Modulation of

hMSC Proliferation and Differentiation 65

A. Calarco, O. Petillo, M. D 'Apolito, S. Margarucci, A. Torpedine, G. Peluso

Development ofBone Substitutes Based on Brushite Cements 66

G. Cama, F. Barbcris, M. Capurro, L, Di Silvio, S. Deb

Glycopolymers and Glyconanoparticles 67

N. Cameron

Spatial Analysis ofthe Degree and Distribution ofBone Mineralization in Relation to Anabolic and

Anti-resorptive Agents Used for Osteoporosis Treatment 68

G. Campbell, R, Bernhardt, D. Scharnweber, S. Boyd

Development ofbioactive glass coatings by High Velocity Suspension Flame Spraying (HVSFS) 69

V. Cannillo, G, Bolelli, R. Gadow, A. Killinger, L. Lusvarghi, A. Sola, N. Stiegler

Structural Characterization of Adaptable Keratin Biomaterials Designed for Biomedical Uses 70

J, Cardamone

A Prevascularized PLLA Scaffold for the Regeneration of Complex Tissues 71

F. Pavia, V. La Carrubba, G. Ghersi, V, Brucato

In Vitro Osteogenesis on a Highly Bioactive Glass Ceramic (Biosilicate®): Effects of Surface

Conditioning and ofIts Ionic Dissolution Products 72

L. De Castro-Raucci, L. Teixeira, R. Fernandes, F. De Oliveira, O. Peitl-Filho, E. Zanotto, A. Nanci, A. Rosa, P.

De Oliveira

Silk Fibroin Elcctrospun Tubular Matrices as Innovative Small Caliber Vascular Grafts 73

V. Catto, B. Bonandrini, A. Alessandrino, G. Freddi, S. Fare, A. Remuzzi, M. Tanzi

Size-dependent Efficiency of Gold Nanoparticles As Non-viral Vectors for Gene Delivery 74

V. Cebrian, M. Arruebo, F. Martin-Saavedra, C. Vague, J.Santamaria, N. Vilaboa

Engineered Skeletal Muscle using Pam Scaffold 75

D. Cei, E. Loro, A. Malena, C. De Maria, L. Vergani, G. Vozzi

Yeast Chitin-Glucan Complex 76

B. Chagas, F. Freitas, A. Ferreira, L. Mafrai, J. Cortez, M. Reis, R. Oliveira

Synthesis of Segmented Polyurethanes with either Glutathione or Cysteine as Chain Extenders 78

L. Chan-Chan, A. Perales-Alcacio, R. Vargas Coronado, J. Cervantes-Uc, J. Cauich-Rodriguez

Autologous Extracellular Matrix Scaffolds Prepared by a Template Method 79

G. Chen, H. Lu, T. Hoshiba, N. Kawazoe, T. Tateishi

Human Protein Adsorption and Leukocyte Adhesion to PP & PET Meshes with Gas Plasma

Treatment 80

R, Chen, N. Bryan, O. Lefranc, V. Bayon, J. Hunt

Rheological Properties of Magnetically Aligned Collagen Fibril Hydrogels 81

S. Chen, T. Ikoma, N. Hanagata

Blood Coagulation on Titanium Surface with Different Ti02 Crystal Structures 82

Z. Chen, Y. Chen, H. Huang

Homogeneity ofNanohydroxyapatite - Poly{lactide-co-glycolide) Composite Biomaterials 83

J. Chlopek, A. Morawska-Chochol, E. Menaszek, K. Gryn

Gradient Biomaterials for Bone Surgery 84

J. Chlopek, K. Migacz, M. Bujniak

Modelling Yttrium Aluminosilicate Glass for Radiotherapy 85

J. Christie, A. Tilocca

Titanium Doped Phosphate Glass - Effective Bioactive Filler for Polymers 86

W. Chrzanowski, E. Abou Neel, K-Y. Lee, A. Bismarck, M. Dalby, J. Knowles

Plasma Cleaning - An Effective Method to Improve Human Cell Response to Nickel Titanium Alloy? 87

W. Chrzanowski, V. Salih, J, Szade, E. Abou Neel, A. Hart, M. Dalby, J. Knowles

PLLA Fibre Reinforced Composites for Load Bearing Implants Applications 88

W, Chrzanowski, Z. Mustafa, K. Tanner

In Vitro Evaluation of a Novel Porous Scaffold Based on a Natural Sponge Template for Bone Tissue

Engineering 89

S. Clarke, E. Cunningham, S. Choi, M. McKechnie, G. Burke, N. Dunne, G. Walker, F. Buchanan

Assembly of Type IV Collagen and Laminin on Substrates with Controlled - OH density 90

N. Coelho, C. Gonzalez-Garcia, M. Sanchez, G. Altankov

Stemming Vision Using Stem Cells - Seeing is Believing 91

P. Coffey

Design and Fabrication of Hierarchical Macro-mesoporous SiO2-P205 Scaffolds for Bone Tissue

Engineering 92

M. Colilla, 1. Izquierdo-Barba, A. Garcia, C. Lopez De Laorden, M. Vallet-Regi

Injectable Type II Collagen/Hyaluronan Hydrogel as a Adipose Derived Stem Cells Reservoir Systemfor Nucleus Pulposus Regeneration 93

E. Collin, S. Grad, M. Abu-Rub, D. Zeugolis, J. Guicheux, P. Weiss, M. Alini, A. Pandit

Three-dimensional Processing of Calcium Phosphate by Laser Cladding 94

R. Comesana, F. Lusquinos, J. Del Val, A. Riveiro, F. Quintero, M. Boutinguiza, J. Pou

Nanostructured Hybrid Bioactive Glass/ PLA Fibers for Angiogenesis and Bone Regeneration 95B. Contreras, O. Castano, E. Engel, M. Mateos-Timoneda, J. Planell

Bioactive Titania Based Composites for Antibacterial Applications 96

D. Cortes-Hernandez, W, Ortega-Lara, D, Renteria-Zamarron, L. Bretado-Aragon, J. Escobedo-Bocardo, J,

Almanza-Robies

The Development of Small Area Chemically Defined Nano-Arrays for High Throughput Screening:Defining Fundamental Parameters That Can Control Mesenchymal Stem Cell Differentiation at the

Nano-Scale 97

J. Curran, A. Hernandez-Santana, D. Graham, N. Amro, R. Sanedrin, B. Fedderson, M. Nelson, H. Jamil, J. Hunt

Protein, Cell and Bacterial Fouling Resistance on Hyaluronic Acid Modified Polymer Surfaces 98

R. D 'Sa, P. Dickinson, J. Raj, B. Meenan

A Three Dimensional In Vitro Model for the Assessment of Neurite Growth 99

W. Daly, M. Abu-Rub, D, Zeugolis, C. O'Connell, L. Yao, A. Pandit

Elastin like Polypeptide Based Hollow Spheres for Gene Delivery 100

B. Dash, S. Mahor, M. Monaghan, O. Carroll, K. Woodhouse, A. Pandit

Collagen-Hyaluronic Acid Scaffolds for Mammary Gland Tissue Engineering 101

N. Davidenko, J. Campbell, C. Watson, R. Cameron

Role of Intracellular Forces on Topographically-induced Nuclear Deformation in Cancerous Cells 102

P. Davidson, O, Fromigue, J-N. Freund, P. Marie, V. Hasirci, G. Reiter, K. Anselme

The Nanostructure of Human Teeth: A Scanning Small-Angle X-ray Scattering Study 103

H. Deyhle, O. Bunk, B. Muller

An Approach to Design 3D Rapid Prototyped Poly(E-caprolactone)/Iron Oxide NanocompositeScaffolds for Tissue Engineering 104

R. De Santis, A. Gloria, T. Rvsso, U. D'Amora, S. Zeppetelli, C. Dionigi, A. Dediu, L. Ambrosio

Design of Surfaces with Mechanical Nano-Heterogeneities for a Better Control of Cell-Material

Interactions 105

S. Degand, F. Jiang, C. Dupont-Gillain

Bioimplant Surface Nanoscaled Functionalization on Electrical Potential Deposition to Attach

Osteoblasts and Generate Bone Tissue 106

Y. Dekhtyar, I. Khlusov, N. Polyaka, R. Sammons, F. Tyulkin

Activation ofPolyurethane Scaffolds by Surface Treatment with Diamines and Heparin 107

E. De Mulder, D. Lowik, M. Kaens, D. Janssen, G. Hannink, N. Verdonschot, P. Buma

Shape Memory Polymer Foams for Biomedical Applications: The Role of Transformation Processes 108

L. De Nardo, S. Bertoldi, M. Tanzi, H. Haugen, S. Fare

A Modular Bioreactor for Mechanical Conditioning of Tissue Engineered Constructs: An Applicationon Endothelial Cells 109

S. Dermenoudis, Y. Missirlis

Different Surface Modification Techniques Have the Ability to Improve the Performance of

Biodegradable Scaffolds Produced by Rapid Prototyping 110

T. Desmet, E. Berneel, H. Declercq, D. Van Loo, R. Cornelissen, E. Schacht, P. Dubruel

Fatigue ofSelective Laser Melted Titanium Ill

M. De Wild, R. Schumacher, M. Szymanski, M. Wulhrich, A. Walter, S. Fabbri, M Jeker, E. Schkommodau

A Novel XRD Sample Preparation Technique Simulating Physiological Conditions 112

N. Doebelin, M. Bohner

Antimicrobial Effective and Degradable Urinary Bladder Implant 113

M. Doser, S. Oberhoffner, E. Held, M. Milwich, H. Planck

Casein-loaded Hydrogels as Biomaterials for Controlled Biomimetic Mineralisation in Hard Tissue

Regeneration 114

D, Dragusin, A. Lungu, C. Tucureanu, A. Salageanu, D. Vasilescu, H. Iovu, I. Standi

In Vitro Dissolution Behaviour of Calcium Phosphate Coatings on Ti6AI4V Substrate Elaborated byPulsed Electrodeposition Current 115

R. Drevet, F. Velard, J. Faure, S. Potiron, D. Laurent-Maqu'm, H. Benhayoune

Applications ofPicosecond Ultrasonics to Probe Cell Compressibility and Adhesion in a Single Cell 116

M. Ducousso, C. Chollet, T. Dehoux, C. Rossignol, B. Audoin, C. Chanseau, O. Zouani, M-C. Durrieu

Structural and Mechanical Properties ofSilk Fibroin Scaffolds 117

L. Durselen, A. Seitz, L. Kreja, N. Skaer, K. Gellynck, O. Kessler, A. Ignatius

Peptide Bearing Degradable Polymer Platform for the Fabrication of Injectable Cell Carriers 118

C. Duxbury, S. Delamarre, A. Dias

Biomedical Applications of Resorbable Polymers - An Industrial Perspective 119

M. Eenink, M. Van Alst, M-A. Kruft, R. Van Tuil

Heparin Immobilization onto Plasma Modified Polyethylene Terephthalate to Improve Blood

Compatibility 120

S. Eftekhari

Characterization ofIsolated Populations of Human Dental Pulp Cells 122

O. Egbuniwe, L. DiSilvio, A. Grant, T, Renton

Preparation and Antibacterial Activity ofantibiotic Grafted Thermo-responsivc HyaluronanHydrogel for Infection Prophylaxis 123

D. Eglin, M. Alini, R, Richards, T. Moriarty

Synthesis, Characterization and Bioactivity Evaluation of Bioactive Glass Nanoparticles 124

A. El-Kady, M. Farag

Small Caliber Vessels from Very Fine P(L/D)LA 96/4 Fibers 125

V. Ella, A. Rajala, M. Kellomaki

Gelatin Immobilization onto Chitosan-Alginate Substrate as a Natural Double-Layer CompositeScaffold 126

P. Manesh, R. Haghjoo, A. Karkhaneh, M. Joupari

Processing Effects on Mechanical Properties of a Novel Resorbable Biomaterial 127

A, Elleray, J. Wilson, G, Webster, D. Langton, L. Mulvaney-Johnson, A. Kelly, D. Farrar, B. Wilson, M. Jarman-

Smith

Poly(E-caprolactone) Based Resin for Use in Stereolithography 128

L. Elomaa, H. Korhonen, R. Hakala, D. Grijpma, J. SeppalaNovel Antibiotic-Eluting Wound Dressings: In-vitro and In-vivo Study and Engineering Aspects in the

Dressing's Design 129

J. Eisner, A, Shejy-Peleg, I. Berdicevsky, M. Zilberman

The Influence ofTopography on the Initial Cell Adhesion Studied by Single Cell Force Spectroscopy 130

P. Elter, T. Weihe, R. Lange, J. Gimsa, U. Beck

Novel Polysaccharide-derived Hydrogel Prevents Perineural Adhesions in a Rat Sciatic Nerve

Adhesion Model 131

N. Endo, M. Yamamoto, M. ho, H. Kaneko, H. Hirata

Investigation of the Hydroxyapatite Obtained as Hydrolysis Product of a-Tricalcium Phosphate by

Transmission Electron Microscopy 132

M. Espanol, J. Portillo, J, Manero, M. Ginebra

Bone Reconstruction in Irradiated Areas: Comparison between Mesenchymal Stem Cells and Total

Bone Marrow in Association with Calcium Phosphate Scaffold 133

F. Espitalier, C. Vinatier, E. Lerouxel, N. Durand, J. Guicheux, P. Pilet, F. Moreau, G. Daculsi, P. Weiss, 0.

Malard

Antimicrobial Activity ofSilver Doped Brushite Cement 134

A. Ewald, D. Host, S. Patel, L. Graver, J. Barralet, U. Gbureck

Dissolution Behavior of Bioactive Glass Fibers Containing Sodium and Potassium 135

S. Fagerlund, L. liupa, J. Tuominen, T. Lehtonen, M. Hupa

Improvement of Glucose Biosensor Response by Electrolytic Deposition of Gold Coating 136

Z Fahimi, M. Rabiee, M. Arjmand, M, Shayan

Porosity and Computational Flow Analysis for Collagen-membrane and Cross-linked Gelatin

Scaffolds Using a High Contrast MicroCT with Submicron Resolution 137

G. D'Urso Labate, F. Pennella, F. Consolo, P. Gentile, U, Morbiducci, S. Lau

Characterization of Pectin-coated Polyetbylenimine Polyplexes As Effective Gene Delivery Systems 138

A. Fattahi, D. Pezzoli, J. Varshosaz, M. Golozar, H. Mohammad-Sadeghi, P. Petrini, M. Tanzi, G. Candiani

UV Evaluation of Polyplex/pectin Micro- and Nano-particles for Gene Therapy 139

A. Fattahi, P. Petrini, F. Munarin, M. Golozar, J. Varshosaz, M. Fathi, M. Tanzi

Evaluation ofMesenchymal Stem Cell Phenotype Following Culture on Novel PLGA Particulate

Scaffolds with Four Different Surface Chemistries 140

S, Fawcett, J. Curran, N. Rhodes, L. Hamilton, M. Alexander, K. Shakesheff, J. Hunt

Controlled PLGA degradation within Calcium Phosphate Cement for Bone Tissue Engineering 141

R. Felix Lanao, M. Lopez Heredia, S. Leeuwenburgh, J. Wolke, J. Jansen

Synthesis of Biodegradable Nanoparticlcs Designed for Ophthalmic Drugs Release 142

P. Ferreira, F, Rouxinol, M. Gil, J. Coelho

Titanium Alloy with Small Boron Addition - Mechanical Properties and Osteoblast Reaction 143

F. Feyerabend, O. Ferri, E. Rzeszutek, A. Schreyer, R. Willumeit, T. Ebel

Improved Bone Implants by Plasma Amino Functionalized Titanium Surfaces 144

B. Finke, H. Rebl, B. Nebe, C. Zietz, R. Bader, U. Walschus, M. Schlosser, K. Schroder

Improved Mechanical Properties and Bioactivity of Scaffolds for Tissue Engineering 145

A. Finne-Wistrand, K. Mustafa, A-C. Albertsson

Improved In Vitro Testing of Degradable Magnesium 146

J. Fischer, D. Proefi-ock, N. Hon, R. Willumeit, K. Kainer, A. Schreyer, F. Feyerabend

Amino Functionalisation of Biopolymers using Atmospheric Pressure Plasma Modification 147

C. Flynn, R. D'Sa, C. Byrne, B. Meenan

Alginate Hydrogels Functionalized With a Protease-Sensitive Motif as Dynamic Microenvironments

for 3D Cultured Stem Cells 148

K. Fonseca, S. Bidarra, M. Oliveira, P. Granja, C. Barrias

A Novel Surface Modification Enabling Local Administration of Strontium from Implants 149

J. Forsgren, H. Engqvist

Development of Load Bearing Fiber Reinforced Composites for Medical Devices 150

M. Foulc, K. SiposNovel Fucose-Containing Bacterial Exopolysaccharide 151

F. Freitas, V. Alvesi, C. Torres, M. Cruz, R. Marques, R. Oliveira, M. Reis

Optimization ofFiber Diameter in Electrospun Fibermat for Three Dimensional Tissue EngineeringScaffold 152

K. Fvjikura, A. Obata, T. Kasuga

Increase of the Working Time of PMMA-based Bioactive Bone Cements by Using SPD-PMMAPowder 153

C. Fukuda, K. Goto, M. Jmamura, T. Nakamura

Modelling Drug Delivery from Stents Through a Finite Element Analysis 154M. Gagliardi, D. Silvestri, C. Cristallini

Synthesis and Characterization ofa Novel pH-sensitive Nanocarrier for Targeted Drug Delivery 155

M. Gagliardi, D. Silvestri, C. Cristallini, N. Barbani

Influence of Sintering Temperature, Sintering Type and Ca/P Ratio on Injectability of CaP-BasedPastes 156

L. Galea, M. Habib, G. Baroud, M. Bohner

Staphylococcal Adhesion to the Surface of Ti6A14V after Silicon-implantation 157

A. Gallardo-Moreno, M. Gonzalez-Martin, M. Pacha-Olivenza, J. Gonzalez-Carrasco

Hybrid Natural Injectable Scaffolds for Cartilage Regeneration 158

T. Martinez, D. Cruz, J, Ribelles, G. Ferrer

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Design ofNanofibrous Platforms for Bone Regeneration by Tuning Morphological and Chemical

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Bio-Analogues for Controlled Angiogenesis in Tissue Regeneration 181

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Porous Freeze-dried Scaffolds for Tissue Engineering 183

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Drug Release from Photocrosslinked Poly(ester anhydrides) 186

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Development of Methods for Testing the Toxicological Profile of Nanoparticles Used in the

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Manual Segmentation of Lymphoma forMRI Texture Analysis 190

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Bioactive Glass Granules - A Suitable Bone Substitute Material in the Operative Treatment of

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Porous Hollow Poly(3-hydroxybutyrate) Fibres as Absorbable Nerve Guide Conduits 200

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Surface Modification of Macroporous Methacrylate Hydrogels for Incorporation of Bioactive

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Galactose-Fu nationalized Substrates for Selective Cultivation of Primary Human Keratinocytes 202

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Injection Moulding and First Clinical Test of a New Resorbable Medical Device - LigaTie® 205O. Hoglund, K. Olsson, R. Hagman, N, Borg, A-S. Lagerstedt

A Simple and Efficient In Vitro 3-d Tumor Model on a Porous Scaffold 206

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Preparation of Microcapsules Based on Natural Polymers Using a Double Emulsion Technique 207M. Holban, C. Peptu, A, Jatariu, D. Jurea, M. Popa, V. Sunel

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Clinical Applications on MRI Texture Analysis 209

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Drug Release Behaviors ofPorous Hydroxyapatite Spheres accordance with Structural Difference 210

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In Vitro and In Vivo Performance of A Novel Dual Drug-Eluting Stent (DDES) 211Y. Huang, S. Venkatraman, F. Boey, E. Lahti, P. Umashankar, M. Mohanty, S. Arumugam, L. Khanolkar, S.

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Biodegradability vs. Bioactivity ofGlasses 213L. Hupa, S. Fagerlund, D. Zhang, M. Hupa

Biocomposites in Sports Medicine: A Novel Bioabsorbable Composite Material 214

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Controlled Surface Adsorption of fd Filamentous Phage by Tuning of the pH and the

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3D Imaging of Biomaterials - from Tissue to Material Structures and Functions 216

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Testing of Collagen-Mimetic Dried Hydrogels with Different Gelators for Culturing of Human

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Comparison of Additives to Modify Setting Time of Tricalcium Phosphate Cements 218

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Antifhrombogenic Materials Constructed by Block-type Phospholipid Polymer and SegmentedPolyurethane for Small-diameter Vascular Prosthesis 220

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Zinc Phosphate Coating on Titanium and Its Cell Response 221

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New Nanoparticles Based On Natural And Synthetic Polymers Prepared By An Interfacial

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Protein Anchoring in Silicon Doped Hydroxyapatite 3D-scaffolds Via Biotinylation.... 223

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Synthesis ofZwitterionic Surfaces Based in Bifunctional Silica Ordered Mesoporous Materials 224/. hquierdo-Barba, M. Colilla, S. Sanchez-Salcedo, J. Hueso, M. Val!et-Regi

The Effect of Physical Aging on the Creep Behavior of Acrylic Bone Cements 225

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Calcite-based Material for Tissue Engineering - Optimization of Composition and Technology 227

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Characterization of PEEK Biomaterials and Crystallinity Effects with a Small Punch Testing Method 228

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Genetically Engineered Spider Silk for Disulfide-Mediated Multimerisation and Covalent Coupling 230

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Two Steps Crosslinked Hydrogels Based on Natural and Synthetic Polymers - Preparation andCharacterization 232

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3-D Synthetic Hydrogel Matrices for Neural Tissue Culture 238

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Preparation and Investigation of a Novel Bioglass/forsterite Composite 241R. Mehrizi, A. Yyazdanpanah, R. Ravarian, F, Moztarzadeh

Biological Repair ofthe Intervertebral Disc: Not Yet Ready for Weight Bearing 242

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Surface Scientific Analysis and Surface Modification Methods for Biomaterials Research 243

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Measuring Contractile Cell Forces on Rigid Substrates 263

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In Vivo Application of Modified Bacterial Cellulose Tubes in Regeneration ofDamaged PeripheralNerves 265

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Preparation and Characterization ofCollagen Coated Liposomal Nanospheres for Targeted and

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Advanced Absorbable Polymer and Composite Applications: An Overview to the Sports MedicineMarkets 278

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Texture Analysis for Magnetic Resonance Images of the Brain 279

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Characterization ofthe real surface increasing ofstructured implant materials by Electrochemical

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High Resolution CT Imaging of Bioscaffolds, Calcified and Soft Tissue Beyond the Submicron

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Designing a New Scaffold for Anterior Cruciate Ligament Tissue Engineering 287

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Synergistic Effects in Suppressing Cancer Cell Survival and Proliferation by Co-Delivery ofTRAIL

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Micropattern-Tuning ofPolymeric Membranes Using Room-Temperature Ionic Liquids 292

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A Neuronal Potential of Mesenchymal Stem Cells Within Three-dimensional Gel Matrix 293

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Micropatterning ofPoly(ethyIene terephthalate) with Peptides to Enhance Angiogenesis 295

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Non-invasive Magnetically Triggered Drug Delivery In Vitro 296

F. Leng, S. Webb, J. GoughBifunctional Avidin with Covalently Binding Ligand 297

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A Novel, Feeder Free, Autologous System for Maintenance of Human Embryonic Stem Cell

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Characterization and Optimization ofChitosan Crosslinked Electrospun Nanofibers 303

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The Local Model - A Method to Evaluate the Ability of Surface Topographies to Induce Retention

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Structure and Morphology of Self-assembling Bioactive Polymers in Nanoparticles and Films. A

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Functionalisation ofMesoporous Bioglasses for Long-term Anti-osteoporotic Drug Delivery 308

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Detection of Protein Adsorption on Biomaterial Surfaces by Streaming Potential Measurement 309

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Comparison of Oxidative and Mechanical Properties in 1st- and 2nd-Generation Annealed

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Clinical and Material Performance of Conventional, EtO-Sterilizcd Tibial Components 311

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A Comparison of Sterilization and Packaging Methods for UHMWPE in Total Disc Replacement 312

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Macrophage Adhesion to CH3-, OH- and EG4-terminated Self-Assembled Monolayers: Influence of

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Monitoring the Effect of Silicate Substitution on Protein Adsorption to Hydroxyapatite under

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Monitoring the Effect of Silicate Substitution on Protein Adsorption/Desorption to Hydroxyapatite 315

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Influence of Surface Preparation of Titanium Alloys to Biocompatibility Behavior 316

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Novel, High Strength Methacrylate Composites Containing Calcium Phosphates and Adhesion

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High Strength Calcium Phosphate-Polymer Nanocomposites with Vancomycine - Processing and

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Bioresorbable Polymer Scaffolds by Micromolding in Capillaries 319

M. Malin, H. Korhonen, V. Jokinen, S. Aura, M. Leinikka, S. Franssila, J. Seppala

Polyurethane Based Membranes for Nystatin Delivery: Formulation and In Vitro Assessments 320M. Mandru, M. Popa, L, Gradinaru, M. Ignat, L. Verestiuc, C. Ciobanu

Stabilization ofGold Nanoparticles in Organic Solvents for Use in Drug Delivery Applications 321

J. Manson, D. Kumar, D. Dixon

Antibiotic Releasing from Mesoporous Ceramics: Local Delivery in Bone Infections 322

M, Manzano, D. Molina-Manso, N. Alonso-Rodriguez, J. Eslebcm, J. Doadrio, E. Gomez-Barrena, M. Vallet-

Regi

Evaluation of Fibroblasts Adhesion on Biofuncionalized Ti Surfaces with Type I Collagen 323

N. Marin, E. Salvagni, C. Aparicio, E. Engel, M. Ginebra

Mineral Characteristics in Intertubular Dentine 324

A. Marten, P. Zaslansky, 0. Paris, P. Fratzl

Thermoreversible Injectable Hydrogels from Multifunctional Bioactive Elastin-like Recombinamers 325

L. Martin, A. Girotti, M. Alonso, I. Lopez, J. Rodriguez-Cabello

Characterization of Biphasic Calcium Phosphate Doped with Zirconia 326

S. Masudi, M. Yussoff, Z. Rajion, A.Hussein, D. Mohamad

Preparation and Mechanical Properties of Titania Film on Metal Titanium by Electron CyclotronResonance Plasma Oxidation 327

H. Masumoto, M. Fujikawa, Y. Orii, Y. Honda, O. Suzuki, K. Sasaki

Multi-walled Carbon Nanotubes Reinforced P205-Glass/HA Bioceramic Matrices for Bone Grafts 328

D. Mata, M. Amaral, F. Oliveira, M. Paiva, J. Santos, M. Lopes, R. Silva

Effects ofthe Structure of Biofunctionalized Poly(Iactic acid) on Fibroblast Adhesion 329M. Mateos-Timoneda, 0. Castano, E. Engel, J. Planell

A Linear-Dendritic Hybrid Poly (2-(dimethylamino) ethyl methacrylate) as a Highly Effective Gene

Delivery Vector 330A. Mathew, W. Wang, A. Pandit

Comparison ofthe Mechanical Characteristics of Different Plates and Screws after Sagittal SplitOsteotomy by using Finite Element Method 331

T. Matsumoto, T. Motohashi, M. Nakajima, K. Okuda, K. Kakudo

Improving Designs of Self-assembling Beta-sheet Peptide Hydrogels for New Biomaterials 332

5. Maude, A. AggeliProduction of Submicron Chitosan beads as Target-Specific Carriers ofBioactive Molecules and

Contrast Agents 333

L. Mbundi, S. MeiUe, G. Olivier, M. Santin

Response of Human Mesenchymal Stem Cells to Sputter Deposited Calcium Phosphate Thin Films 334

M. McCqfferty, G. Burke, A. Boyd, B. Meenan

Raman Spectroscopic Monitoring of Osteogenic Differentiation of Human Mesenchymal Stem Cells 335L. McManus, A. Boyd, M. McCafferty, G. Burke, B. Meenan

Variation of Surface Functional Groups of Oxide Nanoparticles and Their Impact on Protein

Interactions 336

F. Meder, T. Daberkow, L, Treccani, K. Rezwan

Chlorhexidine Release Promotion from Dental Composites Via Reactive Calcium Phosphate Addition 337

I. Mehdawi, A. Young

The In Vitro Study ofPoly (E-caprolactone) / Poly (glycolic acid) Nanofibrous Scaffold for Soft Tissue

Engineering 338

R. Aghdam, S. Najarian, S.rEmami, S. Shakhesi, H. Tevaearai, M-N. Giraud

Phosphoserine-Tethered Semi-Dendrimer Films Induce Osteoblast Proliferation and Differentiation

on Titanium-Based Substrates 339

5. Meikle, G. Bianchi, M. Santin

Injectable Apatite / Blood Composite: Development and Characterization 340

C. Mellier, B. Fellah, P. Janvier, I. Khairoun, B. Bujoli, T. Balaguer, N. Rochet, J. Bouler

Multifunctional Polymer/Bioactive Glass Scaffolds for Bone Tissue Engineering 341D. Meng, L. Francis, I. Roy, A. Boccaccini

Novel Magnesium Phosphate Cements with high Early High Strength and Antibacterial Properties 342

G. Mestres, M. Ginebra

Low Molecular Weight Hydrogelators in 2D- and 3D-cell-culturing 343

G. Metselaar, J. Smisterova, E. Bulten, A. Lesire, M. VanDer Sluis, M. DeJong

Properties ofTi02/HAp Composite Material for Bone Surgery 344

5. Michalowski, Z. Jaegermann, A. Chroscicka

Structural, Biological and Mechanical Properties of Highly Dense Collagen Gel Tube for UrinaryTract Tissue Engineering 345

L. Micol, E. Engelhardt, M. Ananta, V. Mudera, J. Hubbell, R. Brown, P. Frey

Platelet-Rich Plasma (PRP) and Hydrostatic Pressure Influence Cell Differentiation in Nucleus

Pulposus-Tissue Engineering 346

A. Mietsch, A. Ignatius, H. Schrezenmeier, U. Mauer, B. Friemert, H-J. Wilke, C. Neidlinger-Wilke

Mechanical Testing of Olecranon Fracture Fixation Model with Metallic or Bioabsorbable Fixation

Methods 347

J. Mikkonen, T. Srinck, K. Paakinaho, H. Heino, I. Sinisaari

Characterisation of Optimised Positively Charged Self-assembling Peptide Gels and Evaluation of

Their Cell Biocompatibility 349

D. Miles, S, Maude, S. Felton, R. Wilcox, E. Ingham, A. Aggeli

Repair ofa Pigeon Long Bone Cortical Defect Filled with Collagen and Autograft Bone 350

N. Mino-Farina, F. Muoz-Guzon, M. Lopez Pena, A, Gonzalez-Cantalapiedra, F. San Roman-Ascaso, J.

Rodriguez-QuirosEvaluation ofCompressive Stiffness of Enzyme-treated Cartilage Using Electric Impedance Method 351

M. Miyashila, Y, Morita

Fabrication of Hybrids from Apatite and Collagen Immobilized with Polyglutamic Acid 352

T. Miyazaki, A. Hirakawa, Y, Morita, E. Jshida, C. Ohtsuki

Experimental Study on the Biological Interface of a Deproteinized Bovine Bone Grafting Material 353

Z. Mladenovic, A. Shchukarev, A. Sahlin-Platt, B. Andersson, A. Johansson, E, Bjorn, M. Andersson, M. Ransjo

Bioactive Root Canal Filling Materials 354

D. Mohn, M. Zehnder, C. Bnthin, T. Imfeld, W. Stark

Scaffold Mediated Delivery of MicroRNA Immuno-polyplexes 355

M. Monaghan, A. Matthew, U. Greiser, W. Wang, A. Pandit

Local Application ofRosuvastatin Increase BMP-2 Expression in Experimental Critical Size Bone

Defects 356

M. Monjo, M. Ruberl, J. Wohlfahrt, H. Ronold, J. Ellingsen, S. Lyngstadaas

Photocrosslinked poly(ester anhydride) for Controlled Delivery of Peptide YY3.36 357

J. Monkare, R. Hakala, M. Kilpelainen, K. Herzig, H. Korhonen, J. Seppala, K. Jarvinen

Injectable Soy Bean-Hydroxyapatite Cements and Foams for Bone Regeneration 358

E. Montufar, T. Traykova, E. Schacht, L. Ambrosio, M. Santin, J. Planell, M. Ginebra

Study ofGlass Transition Temperature of Two Light-cured Orthodontic Composites 359

J. Moraes, M. Sostena, E. Kamimura, C. Grandini

Effect of Pulse Electric Field Stimulation on the Activity of Chondrocytes 360

Y. Morita, S. Nakasuji, E. Nakamachi

Radio-Opaque Bioactive Glass Markers for Radiostereometric Analysis (RSA) 361

A'. Moritz, R. Madanat, E, Vedel, E. Svedstrom, U. Aro

Controlled Release ofSubstances Bound to Fibrin-anchors 362

T. Morton, K. Schobitz, M. Van Griensven, H. Redl

Electrochemically Deposited Metal Doped Calcium Hydroxide Coatings 363

C. Moseke, M. Hipp, U. Gbureck

Electrochemical Investigations for the Assessment of Biomateriai Surfaces Using the Mini-Cell

System 364

W-D. Mueller, H. Hornberger, L. Nascimento, M. Moisel

Bioadhesion on Surfaces in the Oral Cavity - A Combined Surface Analytical Approach 365

C. Mutter, J. Wald, J. Kirch, A. Luders, M. Wahi, W. Hoth-Hannig, M. Hannig, M. Kopnarski, C. Ziegler

Resorbable Polymers for Wound Closure Applications 366

E. Mutter, S. Oberhoffner, H. Hierlemann, M. Doser, H. Planck

Pectin Microspheres Promote Preosteoblast 3-DimensionaI Growth 367

F. Munarin, M, Grellier, S. Guerreiro, P. Petrini, M. Tanzi, M. Barbosa, P. Granfa

Nanofiber Membranes as Drug Carriers 368

M. Munzarova, M. Juklickova, J. Sire, R. Hobzova, S. Kubinova, V. Nolan

Effect of Granule Size of Synthetic Octacalcium Phosphate on Bone Regeneration and Its Solubility 369

Y. Murakami, Y. Honda, T. Anada, S- Morimoto, H, Shimauchi, 0. Suzuki

Fatigue Characterisation ofTricalcium Phosphate Reinforced Polylactic Acid (PLA) Fibre Composite 370

Z. Mustafa, K. Tanner

Nanotextured Electrodes by Ultra Short Pulsed Laser Deposition 371S. Myllymaa, V. Myllymaki, R. Lappalainen

Preparation ofHydrophobized Thermo-responsive Copolymer Brush Surfaces For Thermally-Modulated Chromatography Matrices 372

K, Nagase, M. Kumazaki, J. Kobayashi, A. Kikuchi, Y. Akiyama, H. Kanazawa, M. Annaka, T. Okano

Characteristics of Human Osteoclasts Cultured on Different Bioceramics 373

M. Nakamura, T. Hentunen, J. Salonen, Y. Sekijima, A. Nagai, K. Yamashita

Resident Cardiac Stem Cells on PAM Scaffold for Heart Tissue Engineering Application 374

M. Nardi, C. De Maria, G. Forte, P, DiNardo, A. Ahluwalia, G, Vozzi

Neural Cell Grafts for Transplantation Therapies 375

S. Narkilahti

Intraocular Dorzolamide Controlled Release: In Vitro and In Vivo Studies 376M. Natu, M. Gaspar, C. Ribeiro, H. De Sousa, M. Gil

Mechanical Characterisation of Collagen-based Scaffolds for Meniscus Tissue Engineering 378

A. Ndreu, G. Bahcecioglu, N. Hasirci, V. Hasirci

Surface Treatment Improving Primary Human Renal Proximal Tubule Cell Performance on

Polymeric Membranes for Applications in Bioartificiat Kidneys 379

M. Ni, M. Bin Ibrahim, J. Teo, F. Tasnim, E. Chow, D. Zink, J. YingDistribution ofthe Bioceramic Particles in the Self-Reinforced Polylactide Composites: A Micro-CT

Study 380

T. Niemela, B, Aydogan, M. Hannula, J. Hyttinen, M. Kellomaki

Dexamethasone-releasing Biodegradable Vascular Stents - In Vitro and in Vivo Results 381

R. Nieminen, A. Kotsar, J. Uurto, M. Hamalainen, J. Mikkonen, H. Juuti, J. Leppiniemi, V. Hanninen, T. lsotalo,

M. Talja, J. Salenius, M. Kellomaki, T. Tammela, E. Moilanen

Oxygen Effect on the Mechanical Properties and Biocompatibility ofTi-15Mo and Ti-20Mo Alloys 382

R. Nogueira, J. Martins Jr., R. Araujo, T, Donato, C. Grandini

Effects ofPhase Constitution of Zr-based Alloys on Their Magnetic Susceptibility to Prevent Artifacts

in MRI 383JV. Nomura, S. Suyalatu, R. Kondo, K. Oya, Y. Tsutsumi, H. Doi, T. Hanawa

Novel and Versatile Surface Modification Technique ofPLA for Biomedical Applications 3 84B. Nottelet, S. El-Habnouni, V. Darcos, J-P. Lavigne, X. Garric, J. Coudane

Enhanced Surface Bioactivity of Nanostructured CP-Ti Substrates Processed by Sever Plastic

Deformation 385

M. Novin, S. FaghihiEvaluation of Primary Human Endothelial Cells Cultured on Newly Developed 3D-printable PolymerSurfaces 386

E. Novosel, IV. Meyer, M. Wegener, H. Kruger, K. Borchers, P. Kluger, H. Walles, T. Hirtk

Preparation ofPoly(lactic acid)-based Fibrous Membranes Releasing Silicon Species byElectrospinning 387

A. Obata, T. Kasuga, J. Jones

Strontium-substituted Bioactive Glasses: Materials Characterisation, In Vitro Performance and

Preliminary Large Animal Data 388

M. O 'Donnell, P. Candarlioglu, E. Gentleman, C. Miller, A. Goodship, M. Stevens

The Effect of Metal Chloride Solutions on Coloration and Biaxial Flexural Strength of Yttria

Stabilized Zirconia 389

G. Oh, Y. Seo, K. Lee, D. Lee, H. Kim, M. Vang, J. Koh, H. Lim, S. Park

A Comparative Study ofMarine and Bovine Collagen Within an Injectable Calcium PhosphateCement 390

R. O 'Hara, F. Buchanan, J. Orr, N. Dunne

Expansion of Human Mesenchymal Stem Cells In Vitro - A Microarray Based Gene Expression Study 391

P. O'Hare, G. Burke, M. McCafferty, B. Meenan

Formation ofHydroxyapatite through Double-Step Hydrothermal Processing of Beta-Tricatcium

Phosphate and Dicalcium Phosphate Dihydrate 392

C. Ohtsuki, T. Watanabe, T. Goto, I. Kim

Design of Polylactide-Based Biodegradable Materials Exhibiting Protease-Triggered Hydrolysis UsingSupramolecular Polyrotaxane Structure 393

Y. Ohya, S. Takamido, K. Nagahama, T. Ouchi, R. Katoono, N. Yui

Discrete Modeling of Cell Motion Within a Porous Scaffold Under Perfusion 394

A. Olivares, D. Lacroix

An Osteoblast Induction on RGD and /or BMPs Mimetic Peptide-grafted Polyethylene TerephthalateSurfaces 395

O. El FaroukZouani, C. Chollet, B. Guillotin, M-C. Durrieu

Radioactive Tagging ofCarbon Nanotubes Used In Augmented Bone Cement 397

R. Ormsby, T. McNalfy, C. Mitchell, N. Dunne, D. Martin, P. Halley, L. Gahan, A. Musumeci, S. Smith

The Role of Nanopillars on Adhesion and Orientation of Saos-2 and Bone Marrow Stem Cells 398

H. Ozcelik, J. Ziegler, A. Schleunitz, M. Bednarzik, C. Padeste, V. Hasirci

Mechanically Active Bioabsorbable Shape-Memory Polymers and Composites - Degradation andPerformance 399

K. Paakinaho, H. Heino, M. Kellomaki

Patterning of Cochlear Implant Surfaces 400

G. Paasche, E. Fadeeva, R. Oberbandscheid, J. Koch, B. Volckaerts, T. Lenarz, B. Chichkov, T. Stover

Atomistic Modeling of Amorphous Region of Cellulose Nanofibrils 401

S. Paavilainen, L. Martikainen, T. Rog, J. Jarvinen, J. McWhirter, 1. Vattulainen

SilOss G®: New Monetite/Silica Gel/Bioactive Glass Bone Regeneration Material 402

S. Padilla, R. Garcia-Carrodeguas, N. Acosta, R. Alloza, A. Garcia-de Castro

Gene Expression ofIntegrins a5, ay, a3, Pi and P3 by Osteoblasts Adhered on Plane and Fibronectin-

coated CP. Ti. Effect of Physical, Chemical and Topographical Surface Properties 403

M. Pegueroles, C. Aparicio, A. Aguirre, E. Engel, J. Planell, F. Gil

A Pilot Study of Fiber Reinforced PLA/p-TCP Composite Cages in Sheep Spinal Fusion Model 404

A. Palli, J. Franlzen, H. Heino, S. Miettinen, H, Aro, S. Haimi

Combining TOF-SIMS, SEM, FIB and TEM for Evaluation of Bone Anchored Implants 405

A. Palmquist, L. Emamielsson, P. Sjovall

PoIy(L-lactide-co-glycolide) Scaffolds for the Treatment of Osteochondral Defects: ExperimentalStudy on Rabbits 406

E. Pamu/a, E. Menaszek, P. Dobrzynski, M. Orzelski, P. Silmanowicz

Finite Element Analysis of Teeth Restored with Reinforced Composite Posts 407

T. Papadopoulos, D. Mouzakis, A. Sarafianou, G. Papanicolaou

Experimental Development of Dental Implants Using the Metal Injection Moulding Technology 408

T. PapadopoulosFabrication of Three-dimensional Porous Polycaprolactone Using Rapid Prototyping for Bone Tissue

Engineering 409

S. Park, S. Lee, W. Kim

Immobilization of Specific Receptors for Helicobacter Pylori Using Model Surfaces 410

P. Parreira, A. Magalhaes, C. Reis, D. Leckband, M. Martins

A New Generation of Polysaccharide Hydrogels (Inter Penetrating Hydrogels) with Mechanical and

Biological Properties Different from Native Ones 411

D. Pasqui, M. De Cagna, L. Golini, E. Spera, R. Barbucci

Fibronectin Distribution and Adsorption Onto Surface-modified Single Ti02 (110) Crystals. A Model

Surface to Study the Bio/Non-Bio Interface 412

M. Pegueroles, I. Palacio, O. Castano, E. Engel, C. Aparicio, M. Gonzalez-Barrio, A. Mascaraque, O. Rodriguezde la Fuente, J. Rojo, J. Planell

Characterisation of Nano-structured Ti02 Powder Obtained by Electrolysis 413

E. Pelaez-Abellan, W-D. Mueller, A. Ruiz-Barreto, D. Fernandez-Conde, M. Valdes-Pedroso

A Novel Hydrogel-Based System As A Flexible Tool For Spinal Cord Injury Repair Strategies 414

G. Perale, P. Veglianese, F. Rossi, M. Peviani, D. Llupi, T. Casalini, E. Micotti, G. Forloni, M. Masi

Development of a Controlled Delivery System for an Anti-cancer Drug Nelfinavir 415

E. Perets, A, Rudich, J. Kost

Collagen-Calcium Phosphate Cement Scaffolds for Nonviral Gene Delivery 416

R. Perez, M. Ginebra, M. Spector

Polyacrylate Nanoparticles with Multiple Gdlll Centers as High Relaxivity Contrast Agents for MRI 417

/. Perez-Baena, I. Loinaz, D. Padro, I. Garcia, H. Grande, I. Odriozola

VEGF-Blocking Peptides for Controlled Angiogenesis in Tissue Regeneration and Biomaterials-Based

Anti-Cancer Therapy 418

V. Perugini, A. Guildford, S. Meikle, M. Santin

Improving the Handling ofBone Fillers based on Calcium Phosphates 419

M. Peroglio, L. Gremillard, D. Eglin, S. Verrier, C. Gauthier, L. Chazeau, M. Alini, J. Chevalier

Tailoring Thermoresponsive Hyaluronan-based Hydrogels for Nucleus Pulposus Repair 420

M. Peroglio, D. Mortisen, M, Alini, D. Eglin

Pre-mixed Calcium Silicate Cement for Endodontic Applications 421

C. Persson, H. Engqvist

VEGF-Blocking Peptides for Controlled Angiogenesis in Tissue Regeneration and Biomaterials-Based

Anti-Cancer Therapy 422

V. Perugini, A. Guildford, S. Meikle, M. Santin

Effects of Calcium Silicate-Calcium Phosphate-Coating on Proliferation and Differentiation of

Human Mesenchymal Stem Cells in vitro 423

K. Peters, C. Prinz, S. Adam, A. Salomon, J. Weber, J. Rychly, H-G. Neumann

Influence of Degradation Medium on Ti02-polyester Nanocomposites 424

A. Piegat, H. Jawad, M. El Fray, A. Boccaccini

Poly(Dimethyl Siloxane) Surface Modification by Low Pressure Plasma to Improve Its

Characteristics Towards Biomedical Applications 425

S. Pinto, P. Alves, C. Matos, A. Santos, L. Rodrigues, J. Teixeira, M, Gil

Anti-inflammatory Drug Loaded Electrospun Poly(Trimethylenc Carbonate-co-E-caprolactone)Fibers for Nerve Regeneration 426

L. Pires, V, Guarino, C. Barrias, L. Ambrosio, A. Pego

Functionalized Polypropylene Net for Incisional Hernia Repair 427

M. Plencner, E. Prosecka, M, Rampichova, B. East, L. Vyslouzilova, R. Jakubova, D. Lukas, E. Amler

Mechanically Switchahle Antibacterial Coatings For Soft Biomaterials 428

L. Ploux, A. Airoudj, E.KulagAntibacterial Properties of A New Antibiotic-Loaded Microporous Bioceramic 429

L. Ploux, M. Mateescu, L. Guichaoua, K. Anselme, E. Champion, D. Chulia, M. Viana, R. Chotard-Ghodsnia

Prosthetic Wear Measurement in Total Knee Arthroplasty Using Phase Shifting Profilometry 430

M. Pochmon, T. Rossler, J. Gallo, M. Hrabovsky

Hematopoietic Stem Cell Fate Controlled by Extracellular Matrix Microcavities 431

T. Pompe, E. Muller, I. Kurth, K. Franks, C. Waskow, M. Bornhauser, C. Werner

PoIy(Trimethylene Carbonate) Scaffolds for Vascular Tissue Engineering 432

A. Poot, Y. Song, J. Wennink, M. Kamphuis, I. Vermes, J. Feijen, D. Grijpma

Long-term Performance of High-Density PoIy(ethyIene glycol) Grafted -to- Po!y(DOPAmine) Layers 433

O. Pop-Georgievski, S. Popeika, V. Proks, J. Jaros, A. Hampl, F. Rypacek

Natural Polymer-Based Hydrogel Prepared by Graft Co-polymerization of Collagen 434

S, Potorac, M. Popa, L. Verestiuc, E. Tanase

Laser Processing and Synthesis of Biomaterials 435

J. Pou, F. Lusquinos, F. Quintero, R. Comescma, A. Riveiro, M. Boutinguiza

Oxygen Plasma Treatment ofPEEK to Improve Human Primary Osteoblast Cytocompatibility 436

A. Poulsson, R. Richards

Homogenous Morphology Control ofCarbonate-Substituted Hydroxyapatite Block Prepared byDouble-Step Hydrothermal Method 437

S. Parthiban, C. Ohtuski

"Click & Seed" Approach to the Biomimetic Modification of Polymers 438

V. Proks, J. Jaros, 0. Pop-Georgievski, S. Popeika, J. Kucka, A. Hampl, P. Dvorak, F. RypacekEnriched Composite Scaffolds used as a Drug Delivery System for Osteochondral Regeneration InVivo 439

E. Prosecka, E. Filova, M. Rampichova, A. Mickova, M. Plencner, L. Martinova, A. Lytvynets, J. Uhlik, J. Motlik,E. Amler

Survival and Function of Dermal Fibroblasts Seeded in Novel PLLA-Collagcn Constructs for the

Reconstruction ofAbdominal Wall Tissue In Vivo 440

F. Pu, N. Rhodes, Y. Bayon, J. Hunt

PEG based Polymers for the Development of Synthetic Tissue Matrices 441

D. Pufky-Heinrich, A. Southan, M. Dealing, V. Schonhaar, A. Schumacher, S. Thude, M. Kaufmann, H. Walles, T.

Hirth, G. Tovar

Concept of Injectable Calcium Ceramic Polymer Composite 442

M Puska, J. Korventausta, H. Sihvonen, G. Orlygsson, P. Vallittu, A. Aho

Highly Porous Nano-Structured Films Loaded with Bioactive Agents for Biomedical Applications:Structure - Release Profile Effects 443

A. Rachelson, A. Kraitzer, M. Zilberman

Effect of Initiators and Polymerization Times on Copolymer ofStyrene_methyl Methacrylate to Make

Thin Carbon Paste for Electrochemical Biosensors 444

M. Rahimnejad, M. Rabiee, Z. Fahimi, S. Rezvaninejad

Synthesis ofStyrene_Methyl Metacrylate Copolymer for the Fabrication of Carbon Paste Electrodes

in Biosensor Application 445

M. Rahimnejad, M, Rabiee, Z. Fahimi, S. RezvaninejadEffects ofSurface Energy on Adhesion and Proliferation of MG 63 Osteoblast like Cells 446

J. Raj, R. D'Sa, P. Dickinson, A. Brown, B, Meenan

Preparation and Characterization ofPolypyrrole Coated Polylactide Non-wovens 447

A. Rajala, L. Jaatinen, M. Hiltunen, J. Pelto, V. Ella, J. Hyttinen, M. Kellomaki

Fabrication and Characterization of Bioactive PLA Fibers for Bone Tissue Engineering 448

/. Rajzer, M, Rom, J. Fabia, E. Sarna, J. Janicki

Nano Hydroxyapatie Polylactic Acid Electrospun Scaffolds for Bone Tissue Engineering 449

/. Rajzer, W. Chrzanowski, W. Binias, E. Sarna, J. Janicki

Bioresorbable Calcium-Deficient Hydroxyapatite-Polylactide Nanocomposites with ChemicallyModified Organic-Inorganic Interfaces 450

A. Rakovsky, E. Gutmanas, I. Gotman

Spark Plasma Sintering ofIonomer Glasses: Effect ofSr Substitution for Ca on the Microstructure

and Properties 451

P. Ramakrishnan, N, Saha, B. Basu, A. Stamboulis

A Simple Drug-anchoring Nanofiber Scaffold for Chondrocyte Seeding and Proliferation 452

M. Rampichova, L. Martinova, E. Kostakova, E. Filova, A. Mickova, J. Michalek, M. Pradny, A. Necas, D. Lukas,E. Amler

Novel Injectable-Biodegradable Hydrogel System for the Treatment ofPeriodontitis and

Perimplantitis 453

F. Rasoul, D. Wang, D. Hill, H. Peng, A. Symons, S. Varanasi, A. Whittaker

Sol-gel Method As Promising Route to Develop Bioactive Scaffolds for Bone Tissue Engineering 454

M. Raucci, V, Guarino, V. D'Anto, L. Ambrosio

A New Injectable Bone Substitute Combining Calcium Phosphate/Phosphoserine Terminated Semi-

Dendrimers Based Gels for Bone Tissue Engineering 455

M. Raucci, S. Zeppetelli, S. Meikle, L. Ambrosio, M. Santin

Nano- and Micro-Structured Hybrid Platforms for Stimulation and Guidance ofSkeletal Muscle

Cells 456

J. Rami, M. Kita, A. Quigley, E. Kennedy, S. Moulton, R. Kapsa, G. Clark, G. Wallace

Cell Architecture on Plasmafunctionalizcd, Structured Metal Surfaces 457

H. Rebl, B. Finke, C. Matschegewski, S. Staehlke, R. Lange, D. Kern, U. Beck, K. Schroeder, J. Nebe

Injectable Hydrogels Containing Marine Polysaccharides For Bone and Cartilage Tissue Engineering 458

E. Rederstorff C. Vinatier, P. Pilel, S. Sourice, S. Colliec-Jouault, J. Guichewc, P. Weiss, S. Laib

Matrix Remodelling on Mixed Self-assembled Monolayers 459

P. Rico, V. Llopis, D. Moratal, M. Salmeron-Sanchez

Interaction of Human Blood Plasma with PEG Surfaces; Identification ofPlasma Protein Deposits 460

T. Riedel, C. Rodriguez-Emmenegger, E. Brynda, Z. Relcheltova, P. Majek, J. Dyr

Fibrous Scaffolds for Cardiovascular Tissue Engineering Made from Solution-Spun P(L/DL)LA 70/30 461

M. Rissanen, A. Puolakka, C. Mariani, T. Deichmann, D. Schmidt, P. Nousiainen

Surface Modification ofPEEK to Improve Osseointegration - The Effect on Bacterial Adhesion 462

E. Rochford, T, Moriarty, R. Richards, A. Poulsson

Novel Synthesis ofNon-Fouling Core-Shell Polymeric Nanocapsules and Nanospheres for Biomedical

Application via Controlled Aqueous Atom Transfer Radical Polymerization 463

C. Rodriguez-Emmenegger, E. Jager, A. Jager, E. Brynda, P. Stepanek, A. Alles, T. Riedel

Fibrinogen and Growth Factors Binding on Calcium Phosphates and Hybrids Materials 464

L. Rodriguez-Lorenzo, B. Moraleda, T. Moreno-Volkmer, R. Jimenez-Gallegos, J. San Roman

Bioactive Scaffolds for Ligament Tissue Engineering 465

G. Rohman, D. Velasquez, S. Huot, V. Migonney

From Rational Design to the Identification ofPromising Polymeric Biomaterials ThroughCombinatorial and High-Throughput Approaches 467

R. Rojas, J. Kohn

A Library of Tunable Hyaluronan-based Dual-functionalized Hydrogels for Various Tissue

Engineering Applications 468

R. Rojas, D. Ossipov, J. Hilborn

Bone Response to Ti Implants with Surfaces Modified by Anodic Spark Deposition 469

A. Rosa, A. Sverzut, G. Albuquerque, C. Delia Valle, R. Chiesa, P. De Oliveira, M. Beloti

Biomimetic Three-Layer Polymeric Systems for Heart Valve Tissue Engineering 470

E. Rosellini, C. Cristallini, N. Barbani, G. Guerra, P. Giusti

Bioartificial Materials for Tissue Engineering: Comparison with Natural Tissues 471

E. Rosellini, N. Barbani, C. Cristallini, G. Guerra

Mesoporous Hybrid Silica Particles as Nanodevices for Cell-Specific Drug Delivery and TargetingApplications 472

J. Rosenholm, E. Peuhu, C. Sahlgren, M. Linden

Computerized Volumetry Predicts Tissue Properties in non-Hodgkin's Lymphoma 473

M. Rossi, H. Pertovaara, P. Dastidar, R. Jarvenpaa, T. Luukkaala, T. Koobi, T. Heinonen, S. Soimakallio, H.

Eskola, P-L. Kellokumpu-Lehtinen

MRI Vs. CT in Tumour Volume Assessment in non-Hodgkin's Lymphoma During Chemotherapy 474

M. Rossi, P. Dastidar, H. Pertovaara, R, Jarvenpaa, P-L, Kellokumpu-Lehtinen, T. Koobi, T. Heinonen, S.

Soimakallio, I-I, Eskola

Problems of Evaluation of THA and TKA Wear Determination by Means of Optical 3D Method 475T. Rossler, M. Pochmon, J. Gallo, M. Hrabovsky

In Vitro Response of MC3T3-E1 Osteoblast-like cells to Synthetic Proline-rich Peptides 476M Rubert, J. Ramis, S, Lyngstadaas, M. Monjo

Reversible DNA/Magnetic Nanoparticle Gates for Stimuli-Responsive Drug Release 477

E. Ruiz-Hernandez, A, Baeza, M, Vallet-Regi

Characterization of PEG-like Films Obtained in Plasma Condition 478

G. Rusu, D. Spridon, I. Topala, N. Dumiirascu

In Vitro Enhancement of SAOS-2 Cell Calcified Matrix Deposition onto r.f. Magnetron SputteredBioglass-coated Titanium Scaffolds 479

E. Saino, M. Scavone, N. Bloise, P. Mustarelli, L. Visai

Assessment ofBioactivity ofTitanium Oxide-coated Polyethylene Terephthalate 480

T. Saito, M. Takemolo, S. Fujibayashi, M. Neo, T. Kokubo, D. Honjyo, T. Hiraide, T. Nakamura

Design of Novel PCL Scaffolds For Bone Regeneration Applications Via Low Temperature scCC*2Foaming 481

A. Salerno, P. Netti

Synthesis and Characterization of Ce203, Ga203 and ZnO Containing Mesoporous Bioactive Glasses 482

A. Salinas, S. Shruti, G. Malavasi, L. Menabue, M. Menziani, M. Vallet-RegiThe Effect of Calcium Source Quality on the Physiochemical Properties of HydroxyapatiteBioceramics 483

K. Salma, L. Berzina-Cimdina, N. Mironova-Ulmane, N. Borodajenko, V. Zalite, L. Pluduma

Human Mesenchymal Stem Cells Studies on Titanium Surfaces Biofunctionalised with a Genetically-Engineered Protein-Based Polymer ....484

E. Salvagni, M. Navarro, C. Aparicio, E. Engel, C. Rodriguez-Cabello, J. Planell

Bioactivation of Ferrite Chitosan-coated Particles for Hyperthermia Treatment 485

C. Sanchez-Torres, D. Cortes-Hernandez, J. Escobedo-Bocardo, J. Almanza-Robles

Issues in Bone Tissue Engineering: Moving from the Laboratory Towards Clinical Reality 486G. Sandor

Comparison of Different Lactide Based 2D Biomaterial Membranes for Urothelial Tissue EngineeringApplications 487

R. Sartoneva, S. Haimi, A-M. Haaparanta, M. Kellomaki, S. Miettinen, R. Suuronen, T. Lahdes-Vasama

Peptide-functionalised Polyurethanes for Soft Tissue Engineering Application 488

S. Sartori, A. Caporale, A. Silvestri, P. Sera/ini, F. Boccafoschi, G. Ciardelli

Effect ofNoise on Texture Analysis of MR Images 489

5. Savio, L. Harrison, T. Luukkaala, P. Dastidar, S. Soimakallio, H. Eskola

Development of Photopolymerizable Hydrogels for 3D Bioscaffolds by Rapid Prototyping 490

J. Schelfhout, S. Van Vlierberghe, E. Schacht, R. Cornelissen, E. Berneel, P. Dubruel

Alginate-Scaffolds for Cochlear Implant Optimisation 491V. Scheper, F. Ehrhart, H. Zimmermann, T. Lenarz

New Biodegradable Fe-based Alloys for Temporary Cardiovascular Stent Applications 492

M. Schinhammer, A. Hanzi, J. Loffler, P. Uggowitzer

Nano- and Micro-Mechanical Characterization of Hard and Soft Biomaterials: Bone and CartilageStudies 493

P. Coelho, C. Pacione, M. Wimmer, L. Rush, A. Simpson, R. Nay, J. Schirer, S. VengasandraThe Antibody Response Against Synthetic Polymer-based Biomaterials 494

At Schlosser, A. Hoene, L. Wilhelm, M. Patrzyk, U. Walschus, R. Hennrich, R. ZippelBiocompatibility Testing of a Wear-resistant Cobalt Chromium Alloy 495

H. Schneider, K. Schrock, J. Lutz, S. Mandl, M. Schulz-Siegmund, M. KampradElectrospun Fibrin for Peripheral Nerve Regeneration 496

C. Schuh, A. Banerjee, C. Grasl, M. Van Griensven, H. Redl, D. Ruraler, H. Schima, T. Morton

Correlation Between Cell Growth and Fiber Structure - PVDF-fibers for Textile Implants 497

P. Schuster, S. Houis, T. Gries

In Vitro Toxicological Evaluation ofChitosan-based Nanogel Delivery Systems 498

C. Schutz, L. Juillerat-Jeanneret, B. Halamoda-Kenzaoui, C. Wandrey

Surface Modification to Optimize Nanogel-based Antigen Delivery 499

C. Schutz, L. Harwood, P. Kauper, K. McCullough, C. Wandrey

Adhesion and Viability ofOral Bacteria on Charged Self-Assembled Monolayers 500

H. Schweikl, A. Eidt, K-A. Hiller, G. Schmalz, V. Katzur, R. Midler, M. Eichler, F. Rupp, J. Geis-Gerstorfer, S.

Ruhl

Laser Induced Gradients for Surface Functionalization of Polymers 501

N, Seller, E. Bremus-Kobberling, S. Engelhardt, D. Riester, A. Gillner

Fabrication of the New Zirconia Block and Evaluation of the Fit ofPorcelain Veneered Crown 502

r. Seo, G. Oh, K. Lee, K. Lee, H. Kim, H. Yang, J. Kah, H. Lim, S. Park

Chemically Modified Polylactones for Controlled Drug Delivery Applications and for RapidPrototyping of Bioactive Scaffolds 503

J. Seppala, R. Hakala, H. Korhonen, M. Malin, J. Rich

Fabrication ofNovel PLA/PEG/CaP Glass Biodegradable Scaffolds by Rapid Prototyping 504

T. Serra, M. Navarro, J. Planell

Effectiveness ofDifferent Silanes to Immobilize Short Biofunctional Peptides on Titanium Surfaces 505

P. Sevilla, M. Pegueroles, M. Godoy, D. Rodriguez, E. Salvagni, C. Aparicio, F. Gil

Encapsuled Luminescent Water Soluble ZnS Semiconductor Nanocrystals Within Sol-gel Silica for

Bioanalysis Applications 506

M. Shayan, M. Rabiee, F. Moztarzadeh, Z. Fahimi

Micromechanical Characterisation ofFailure in Acrylic Bone Cement Due to Barium SulphateAgglomeration 507

N. Shearwood-Porter, M. Browne, I. Sinclair

Graft Copolymer of Hidroxypropyl-starch and Methacrylic Acid Like Scaffolds for Biomaterial Uses 508

/. Silva, M. Curruchaga, I. Goni

Electrospun Nanofibers as Scaffolds: Morphology and Drug Delivery 509

J. Sire, M. Munzarova, M. Lhotka, P. Kozlik, R. Hobzova, J. Michalek

Bioactive Titania-hydroxyapatite Functionally Graded Coatings: Production, Post-processing and

Characterization 510

A. Sola, D. Bellucci, V. Cannillo, A. Callini

Preliminary In-Vitro Biocompatibility Studies on a Novel Resorbable Biomaterial 511

P. Souter, J. Wilson, D. Langton, G. Webster, B. Wilson, M. Jarman-Smith, D. Farrar

Biomorphic Bone Scaffolds Made of Biomimctic Hydroxyapatite Obtained by Transformation of

Rattan Wood 512

S. Sprio, A. Rufflni, A. Tampieri

Heparin Intercalation as a Competitive Cross-linker in Collagen-based Cell Culture Scaffolds 513

D. Stamov, T. Ngyuen, H. Evans, T. Pfohl, C. Werner, T. Pompe

Influence of the UHMWPE crystallinity on OI and TVI Determination According to ASTM F2102-06

and F2381-04 514

N. Stark, W. Schneider, B. Alcock, R. Klabunde

Bioactive PMMA Bone Cements with Improved Adhesion to Bone Tissue 516

A. Stepuk, O. Schneider, D. Mohn, W. Stark

Porous Polypeptide-based Hydrogels Modified with Cell-adhesion Moieties 517

H. Studenovska, P. Vodicka, V. Proks, J. Juhasova, J. Motlik, F. RypacekEffect of P-Tricalcium Phosphate Addition on the In Vitro Degradation ofReinforced Poly(L-lacticAcid) 518

D. Suarez-Sandoval, R. Wach, A. Olejnik, A, Adamus, K. Ruffieux, J. Rosiak

Non-Viral Gene Therapy and Retinal Pigment Epithelium Tissue Engineering for the Treatment of

Age-Related Macular Degeneration 519

A. Sitbrlzi, S. Van Vlierberghe, G. Subra, M. Amblard, J. Martinez, E. Schacht, P. Dubruel, M. Yliperttula, A.Urtti

Optimization of Moisture Absorption in a Aramid/PolydimethylsiloxaneComposite for OrthopaedicUsage 520

T. Suchy, M. Sochor, Z. Sucharda, R. Sedlacek, K. Balik

Silicon-containing Calcium Phosphate Coatings Deposited by Rf-magnetron Sputtering: In Vitro

Study in a Non-cellular Simulated Body Fluid 521

M. Surmeneva, R. Surmenev, V. Pichugin, S, Chernousava, M. Epple

Osseointegration of Titanium Screws with Antimicrobial Noble Metal Coating 522

S. Svensson, F. Suska, L. Emanuelsson, A. Palmquist, B. Norlindh, H. Karlholm, G. Rydja, M. Ohrlander, J.

Lausmaa, P. Thomsen

The Chemical Modification ofPoly(a -Amino Acid)s Fibrous Scaffolds for Applications in Tissue

Engineering 523

J. Svobodova, V. Proks, J. Kucka, F. Rypacek

Novel Human Albumin Based Biomaterial for Vascular Grafts Sealing 524

A. Szulc, T. Ciach

Unusual HUVEC Adhesion and Anti-thrombogenic Behavior ofCitric Acid-crosslinked Alkali-

treated Gelatin 525

T. Taguchi, M. Inoue, Y. Katada, A. Fujiu, J. Manabe, R. Nagai

Polyelcctrolyte Fibrous Scaffold to Deliver Differentiated hMSCs to the Liver 526

B. Tai, C. Du, S. Gao, A. Wan, J. Ying

Quantification of the Relationship Between Cell Shape and Intercellular Adhesion of Chondrocyteson a Fibroin Substrate 527

Y. Takeda, A. Otaka, Y. Tamada, N. Tomita

Preparation and Characterisation of Targeted Chitosan-Plasmid DNA Nanoparticles 528

E. Talvitie, K. Paavilainen, J. Leppiniemi, A. Mikhailov, V. Hytonen, M. Kellomaki

Accelerated Ageing of Pigmented Silicone Elastomer Nanocomposites, Suitable for Biomedical

Applications 529

P. Tarantili, S. Vasilakos

Preparation, Characterization and Hydrolytic Degradation Studies of Organoclay/poly(Lactic Acid)Nanocomposites for Biomedical Applications 530

P. Tarantili, C. Stathokostopoulou

Human Osteoclast Formation and Activity in the Presence ofPhospfaonate Group-FunctionalisedPolystyrene Nanoparticles 531

A. Tautzenberger, L. Kreja, S. Lorenz, A. Zeller, P. Walther, K. Land/ester, H, Schrezenmeier, V. Mailander, A.

Ignatius

Effect of ta-C Coated and Microstructured Surfaces for Cell Culture Applications 532

A-C. Teichmann, M. P/eiffer, K. Gunther, A. Hubner, S. Feik, S. Welbmantel, P. Radehaus, H. Mittweida

Cathodic Electrospinning ofChitosan 533

D. Terada, C, Yoshikawa, K. Zhang, A. Tiwari, S. Hattori, T. Honda, T. Ikoma, H. KobayashiAerosol Deposition of a -TCP powder 534

K. Teraoka, S. Hirose, S. Murakami, K. Kaio, J. Akedo

Strategies to Increase Initial Corrosion Resistance and Modify Osteoblast Response to Resorbable

Magnesium Alloys 535

R. Thornton, J. GoughFluoride Surface Modification of Ceramic Ti02 and Its Effect on Ostcblastic Cells In Vitro 536

H. Tiainen, M. Monjo, H. Haugen, J. Knychala, 0. Nilsen, S. Lyngstadaas, J. Ellingsen

Surface Signatures of Bioactivity: Multiscale Computer Models of Bioglasses 537

A. Tilocca, A. Cormack

Effects of Vibration Loading on Human Adipose Stem Cell Viability, Proliferation and OsteogenicDifferentiation 538

L. Tirkkonen, S. Haimi, H. Halonen, J. Hyttinen, S. Miettinen, R. Suuronen

Evaluation of Calcium Phosphate and Calcium Sulfate and Bioglass as Carriers for Protein Extract in

Bone Substitutes 539

H. Tolli, K. Sandstrom, P. Jalovaara, T. Jamsa

Reindeer Bone Extract Can Heal the Critical-Size Rat Femur Defect 540

H. Tolli, S. Kujala, T. Jamsa, P. Jalovaara

Cell Adherence on Transparent PVA-H Coated with Extracellular Matrix 541

N. Tomita, H. Kosukegawa, M. Ohta

Biomimetic Scaffolds For Peripheral Nerve Regeneration 542

C. Tonda-Turo, V. Chiono, C, Audisio, E. Cipriani, P. Gentile, S. Geuna, M. Zanetti, I. Perroteau, G. Ciardelli

Resorbable Polymers in Orthopaedics: Past, Present and Future 543P. Tormala, H. Heino

Vitronectin Behaviour on Substrates with Tailored Hydroxyl Content 544

G. Toromanov, C. Gonzalez-Garcia, J. Hernandez, M, Sanchez, G. Jltankov

Characterisation of Zirconia Bars and Implications for Improved Mechanical Resistance in Dental

Applications 545

T. Traykova, C. Mochales, A. Maerten, P. Zaslansky, C. Fleck, W-D. Mueller

Effects of Cathodic Partial Reaction ofTi6A14V Corrosion on Endothelial Cells 546

R. Tsaryk, K, Peters, M. Kalbacova, S. Rossler, U. Hempel, D. Scharnweber, R. Unger, C. Kirkpatrick

Silk/Polyacrylamide Networks for Bone Reconstruction 547

M. Tudor a, C. Zaharia, A. Diacon, C. Cincu, N. Preda, 1. Enculescu

Collagen/PEG-based Matrix for Alzheimer's and Parkinson's Disease Applications 548

M. Tunesi, S. BatelK, T. Russo, A. Gloria, D, Albani, G. Forlorn, L. Ambrosio, A, Cigada, C. Giordano

Novel Resorbable Load-Bearing Composites for Medical Devices 549

J. Tuominen, T. Lehtonen

Multiphoton Microfabrication ofThree Different Photosensitive Biomaterials: Comparison of

Processability and Cytotoxicity 550

S. Turunen, J. Suomalainen, M. Kellomaki

Biomaterials in Retinal Drug Delivery: Nanoparticles and Cell Encapsulation 551

A. Urtti

Animal Study on Bone Tissue Reaction and Metal Ion Release in TNTZ Low Rigidity Titanium Alloy

Learning from failed Femoral Head Replacement in Sheep 552

K. Ushida, T. Hattori, K. Morikawa, T. Akahori, M. Niinomi

Development ofMultiwalled Carbon Nanotube Composite Ceramic Biomaterial 553

Y. Usui, K. Aoki, M. Shimizu, N. Ishigaki, K. Nakamura, N. Ogihara, H. Kato, S. Taruta, M. Endo, N. Saito

Inflammatory Effects of Carbon-fiber Reinforced Peek Particles In Vivo 554

S. Utzschneider, F. Beaker, M. Dedic, B. Sievers, T. Grupp, A. Paulus, V. Jansson

Novel Bioactive yPGA Sol-Gel Hybrid Scaffold for Tissue Regeneration 555

E. Valliant, G. Poologasundarampitlai, J. Jones

Resorbable Coronary Stents: The Ultimate Balance Between Biomechanics, Biocompatibility and

Bioresorption 556

M. Van DerLeest

Study ofthe Osteogenic Differentiation Potential of Bone Marrow Stromal Cells 557

5. Van VJierberghe, L. Fassina, E. Saino, L. Visai, E. Schacht, P. Dubruel

Finetuning of Gelatin Scaffold Architectures using Two-Photon Polymerization 558

S. Van Vlierberghe, A. Ovsianikov, S. Schlie, G. Drager, L. Moller, B. Chichkov, E. Schacht, P. Dubruel

Computational Fluid Dynamics Simulations of Pulsatile Blood Flow in Human Aortic Arch

Reconstructed from Computed Tomographic Images: Study of Flow Profiles and Wall Shear Stress 559

P, Vasava, Z. Mansuri, P. Jalali, M. Dabagh

Preparation and Characterization of Porous Microspheres based on a Naturally Occurring Polymerfor Minimally- Invasive Bone Regenerative Therapies 560

D. Vasconcelos, I. Amaral, C. Barrios, M. Barbosa, C. Ribeiro

Acrylic Ion Exchange Resin/polysaccharide Microparticles As Drug Carriers 561

S. Vasiliu, S. Racovila, I. Bunia, M. Popa, M. Mandru

Development of Bioabsorbable Ciprofloxacin-Releasing Bone Fixation Screws 562

M. Veiranlo, T, Makinen, J, Tiainen, N. Ashammakhi, H. Aro, P. Tormala

HA-mediated activation of Human Polymorphonuclear Neutrophils involves IL-8 pathway activation 563

F. Velard, J. Braux, C. Guillaume, S. Bouthors, E. Jallot, J. Nedelec, D. Laurent-Maquin, A. Belaaoua], P.

Laquerriere

Injectable Microsphere Depots for Controlled Release of Pharmaceuticals 564

G. Veldhuis

A Biodegradable Occcluder for PFO/ASD 565

S. Venkatraman, W. Wu, Y-D. Tang, J. Yip, F. Boey, V. Khoo, D, Duonghong

Development of New, Biodegradable Synthetic Polymers As Non-viral Gene Delivery Systems for the

Treatment of ARMD 567

V, Vermeersch, V. Toncheva, S. Van Vlierberghe, L. Tibaldi, A. Jolioi, P. Dubruel, E. Schacht

MCM-41 Mesoporous Silica for Controlled Delivery of Cisplatin 568

M. Guiza, M. Delgado, C. Arean

Space Directed Vlastopulo Coils for Increasing and Decreasing the Growth ofCells in Biology and

Medicine 569

V. Vlastopulo, V. Nikolaev

The Constructions of Implant Joints on Basis of Elastic Hydrodynamic Theory of Lubricant 570

V. Vlastopulo, V. Nikolaev

Incorporation ofa-TCP Into Porous Scaffolds Obtained Through a Cryopolymerization Technique 571

T. Volkmer, V. Sotisa, L. Rodriguez-Lorenzo, R. Carrodeguas, L. Dos Santos, J. San Roman

Guidance Channels for Reconstruction of Peripheral Nerves -In Vitro and In Vivo Trials 573

R. Wach, A. Adamus, K. Kowalska, A. Olejnik, J. Jozwiakowska, Z. Pasieka, J. Rosiak

Biodegradation and Sterilization Properties of Supramolecular UPy-materials 574

R. Wach, A. Adamus, P, Dankers, A. Olejnik, J. Jozwiakowska, A. Bosman, H. Yuan, J. Rosiak

Physicochemical Properties Forming of Wire Made of AISI3161 for Urology 575

W. Walke, J, Przondziono, J. Szade, A. Winiarski

Examination of the Inflammatory Response Following Implantation of Titanium Plates Coated with

the Phospholipid 2-01eoyl-l-palmitoyl-sn-glycero-3-phosphoethanolamin (POPE) in Rats 576

U. Walschus, A, Kochanowski, A. Hoene, R. Willumeit, F. Feyerabend, L. Wilhelm, M. Schlosser

Biological Characterisation of Clinically Approved Calcium Phosphate Bone Substitutes in

Comparison to a Novel Marine-based Bone Filler for Hard Tissue Repair 577

P. Walsh, G. Walker, S. Clarke, J. Nelson, C. Maggs, F. Buchanan

Biosynthesis of Hydroxyapatite on Grit Blasted Pure Titanium Discs 578

A. Wang, R. Sammons, I. Jones, J. Met, Y. Tse

The Influence of Alkali Treatment on a Biosynthesised Hydroxyapatite Coating on Titanium 579

A. Wang, I, Jones, R. Sammons, J. Mei, Y. Tse

Conductive Polymers as Coating Materials for Neural Prosthesis 580

L, Wang, H. Wang, J. Wang

Variation ofBiological Functions ofHepatocytes Between Biodegradable and NonbiodegradableDevices..... 581

X. Wang

A Human Triple Cell Type Co-culture Model to Analyse Bone Related Cell-Cell Interactions and

Biocompatibility 582

F. Wein, C. Brose, J-P. Kaiser, A. Bruinink

Two-Photon Lithography in Tissue Engineering 583

T. Weib, R. Schade, A. Berg, M. Schnabelrauch, K. Liefeith

Modulating Physical Properties of Biohybrid Hydrogels with Constant Biomolecular Composition 584

P. Welzel, S. Prokoph, A. Zieris, K. Levental, W. Panyanuwai, M. Grimmer, U. Freudenberg, C. Werner

In Vitro Biocompatibility Analysis ofRecombinant Spider Silk Scaffolds 585

M. Widhe, A. Rising, H. Bysell, C. Hillerdal, I. Schenning, M. Malmsten, J. Johansson, M. Hedhammar

Influence ofHydroxylapatite Ceramics with Modified Surface Structures on the In Vitro Generation

ofOsteochondral Implants 586

K, Wiegandt, C. Goepfert, D. Fritsch, T. Richler, R. Poertner, R. Janssen

Association of Systemic Cytokine Levels with the Local Inflammatory Response After Implantation ofPlasma-modified Titanium Plates in Rats 587

L. Wilhelm, U. Walschus, A. Hoene, S. Lucke, B. Finke, K. Schroder, A. Ohl, M. Schlosser

Magnesium Corrosion Under Near Physiological Conditions 588

R. Willumeit, F. Feyerabend, J. Fischer, A. Schreyer, H. Drucker, B. Mihailova, H. Wendel, N. Hort, K. Kainer

PGLA Scaffolds Coated with Collagen and Glycosaminoglycans: Impact on Proliferation and

Osteogenic Differentiation ofHuman Mesenchymal Stem Cells 589

/. Wojak, E. Pamula, R, Hess, P. Dobrzynski, M. Schnabelrauch, D. Scharnweber, V. Hintze

Cell Adhesion to Charged Hydroxyapatite Surfaces 590

C. Wolf-Brandsletler, M. Gregor, S. Tofail, S. Clyens, N. Theilgaard, S. Lang, D. Scharnweber

Silk Modified Nano-mesopore Bioglass Scaffolds for Bone Tissue Engineering 591

C. Wu, Y. Xiao, M. Gelinsky

Development of an Injectable Portland Cement for Orthopaedic Application 592

G. Wynn-Jones, R. Shelton, M. HofmannEffect of Cell Seeding Density on Cell-Biomaterials Interaction 593

Y. Xia, M. Prawirasatya, A, Heng, F. Boey, S. Venkatraman

Fabrication ofEncapsulated Magnetite Microparticles with Hydroxyapatite 594

T. Yabutsuka, T. Nomura, Y. Shimada, T. Yao

Preparation of Bioactive Gum Metal by Surface Treatments 595

S. Yamaguchi, T, Kizuki, H. Takadama, T. Matsushita, T. Nakamura, T. Kokubo

Enhancement of In Vitro and In Vivo Osteogenesis on Titanium Surface with Nano/submicro/micro-

scale Structure 596

W. Yang, M. Lin, J. Chen, H. Huang

Controlling Dispersion ofAxonal Regeneration Using a Multichannel Collagen Nerve Conduit 597

L. Yao, G. Ruiter, H. Wang, A. Knight, R. Spinner, M. Yaszemski, A. Windebank, A. Pandit

Controlled Release of BMP-2 and BMP-7 from Bioplotted Scaffolds Enhances Bone Regeneration In

Vivo 598

P. Yilgor, G. Yilmaz, M. Onal, S. Keskil, B. Kinikoglu, R. Sousa, R. Reis, N. Hasirci, V. Hasirci

3 D Growth of hESC-derived Neuronal Cells in Synthetic Hydrogel 599

L. Yla-Outinen, M. Varjola, H. Skottman, R. Suuronen, S. Narkilahti

Formation ofOrganically Modified Octacalcium Phosphate in a Hydrogel 600

T. Yokoi, H. Kato, M. Kamitakahara, M. Kawashita, C. Ohtsuki

Poly (Diol-co-Tricarballylate):A Novel Photocrosslinked Biodegradable Elastomer for Controlled

Drug Delivery and Tissue Engineering 601

H. Younes, M. Shaker

Bone Forming Ability ofFibroblast Growth Factor Combined Collagen Nanocomposite Membrane

for Periodontal Use 602

H. Yu, H. Lee, J. Park, M. Kim, U. Shin, J. Jang, H. Kim

Optimising Bone Tissue Engineering by Manipulation of Anabolic and Catabolic Responses 603

N. Yu, A. Schindeler, L. Peacock, K. Mikulec, A. Ruys, D. Little

Nano/Microfibrous Scaffolds For Tissue Engineering 604

D. Yucel, H. Kenar, H. Ozcelik, V, Hasirci

Deep Case Hardening ofTitanium Biomaterials by Thermal Oxidation and Vacuum Diffusion 605

S. Zabler, C. Randow, C. Fleck

Development ofthe Porous Bioccramics via Highly Viscous Mass Foaming 606

V. Zalite, J. Locs, I. Freimanis, L. Berzina-Cimdina

Dibenzylidene Sorbitol Derivatives in Polymerization ofMethacrylic Monomers for Dental Use 607

T. Zecheru, A. Lungu, N. Sulca, R. Stan, H. Iovu

Multioxide Bioactive Glass Nanofibers by Electrospinning 608

D. Zhang, H. Guan, A, Harlin, M Hupa, L. Hupa

Computational Simulated Permeability of Titanium Scaffolds for Implant Applications 609

Z. Zhang, D. Jones, P. Lee, J. Jones, C. Sutcliffe, E. Jones

Cryogel/Carbon Composite as an Extracorporeal Haemoperfusion Adsorbent 610

Y. Zheng, C. Howell, S. Sandeman, G. Phillips

Structuring ofFiber-Based Active Implants for Various Applications 611

M. Zilberman

Augmentation of PMMA Denture Base Materials with Multi-Walled Carbon Nanotubes 612

Z. Zoui, C. Mitchell. R. Ormsby, N. Dunne

Novel Elastic Mechanically Strong Nano-Composite Ceramic Scaffold For Orthopaedic Applications 613

S. Roohani-Esfahani, Z, Lu, H. Zreiqat

Core-Shell Microspheres for Delivery of an Aqueous Biologic 614

J, Zupancich, S. Delamarre, A. Dias

Author Index