2.2 histo-male genital
DESCRIPTION
hmgTRANSCRIPT
1. Internal : a. Testisb. Epididymisc. Deferens ductsd. Seminal glandse. Ejaculatory ductsf. Prostate glandg. Bulbourethral
glands 2. External :
a. Scrotum b. Penis
The Male Genital System
STRUCTURES OF THE MALE GENITAL SYSTEM
INTERSTITIAL CELLS
SEMINIFEROUS TUBULE SEMINAL
VESICLE
PROSTATE
RETE TESTIS PENIS
TUBULUS RECTUS EFFERENT
DUCT
EPIDIDYMIS
DEFERENS DUCT
BULBOURETHRAL GLAND
urethra
TESTIS DUCTS ACCESSORY GLANDS
PENIS
Seminiferous tubule 1000X
lumen with sperm
spermatids
spermatocytes
spermatogonia
sustentacular cell
Interstitial (Leydig) cells
• Loose connective tissue
• Crystals of Reinke
in the cytoplasm
• Secretes testosterone
• Controlled by LH from
pituitary
Sustentacular (Sertoli) cells• Nurse cells.• Extend from basal lamina to lumen.• Connected to each other by tight
junctions Blood-testis barrier.• Nourish spermatogenic cells.• Transport spermatogenic cells.• Phagocytize excess cytoplasm.• Secrete ABP, inhibin, transferrin and
antimullerian hormone (during embryogenesis).
BLOOD-TESTIS BARRIER
SERTOLI-CELL TIGHT JUNCTIONS
BARRIER is carefully controlled to allow the passsage of 10
spermatocytes from basal to adluminal compartments
Adluminal Compartment
Basal Compartment
SPERMATOZOON
HEAD
TAIL (flagellum)
NECK
middle piece
Acrosome for digesting zona pellucida
Membrane for recognizing & attaching to Z p
start of Axoneme-microtubular core of tail
Mitochondria as a spiral sheath
coarse Fibrous sheath
principal piece
end piece
highly condensed Nucleus
GENITAL DUCTSGENITAL DUCTSINTRATESTICULAR :INTRATESTICULAR : Tubuli rectiTubuli recti Rete testisRete testis
EXTRATESTICULAR :EXTRATESTICULAR : Eferentes ductsEferentes ducts Epididymis ductsEpididymis ducts Deferens ductsDeferens ducts Ejaculatorius ductsEjaculatorius ducts
DUCTS
DEFERENS DUCTUS
SEMINAL VESICLE
URINARY BLADDER
PROSTATEBULBOURETHRAL GLAND
GLANS
Corpus cavernosum
Corpus spongiosum
URETHRA
SEMINIFEROUS TUBULE
TUBULUS RECTUS
EFFERENT DUCTUS
Ejaculatory duct
RETE TESTIS
PENIS
EPIDIDYMIS
DEFERENS DUCT
ADVENTITIA connecting to other structures of spermatic cord
pseudostratified EPITHELIUM like epididymis’
Thick 3-layered MUSCULARIS int. longitudinal middle circular
out. longitudinal
Small star-shaped lumen
Accessory Genital GlandsAccessory Genital Glands
- - Seminal VesiclesSeminal Vesicles
- Prostate Gland- Prostate Gland
- Bulbourethral Glands - Bulbourethral Glands
(Cowper’s glands)(Cowper’s glands)
PROSTATE GLAND
Main ALVEOLI
URETHRA
EJACULATORY DUCTS
DUCT - one of many
STROMA (collagen & smooth muscle), making the prostate a self-squeezing gland
CAPSULE
CONCRETION (round, layered)
PENIS in CROSS-section
Tunica albuginea Superficial dorsal vein
Buck’s fascia
SkinCorpus cavernosum
Urethra
Corpus spongiosum urethrae
Helicine arteries
Veins
Autonomic & sensory nerves