2018.11 aer lyon intubation v6...bhattacharjee, s., s. maitra, and d.k. baidya, a comparison between...
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Intubation trachéaleDr Jean Baptiste Lascarrou
Médecine Intensive RéanimationCHU Nantes
@JBLascarrou
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Conflits d’intérêt:
• French Ministry of Health:• HYPERION Trial: TTM at 33° or 37° after non-shockable cardiac arrest
• LAERDAL Fondation:• HYPERION Trial: TTM at 33° or 37° after non-shockable cardiac arrest
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Intubation en soins critiques / réanimation
Patient
Device
Operator
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Intubation trachéale
• Préparation• Aspiration, drogues, respirateur, sédation, curares• Optimisation hémodynamique• Checklist: Jaber ICM 2010……. mais Janz Chest 2017
• Préoxygénation
• exPosition• Pas de Sellick: Birenbaum JAMA Surgery 2018
• auscultation Pulmonaire
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Pré-oxygénation
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Characteristics
BVM
N=157
NIV
N=71
HFNO
N=20
NRB
N=71
P value
SAPS II, mean±SD 60±22 58±22 51±20 58±21 0.38
Body mass index, kg·m-2, mean±SD 26 ±7 28 ±9 26 ±5 25 ±5 0.16
Main reason for ETI, n (%)
- Neurological
- Respiratory
- Hemodynamic
- Other
49 (31%)
42 (27%)
48 (31%)
18 (12%)
6 (9%)
50 (70%)
13 (18%)
2 (3%)
2 (10%)
16 (80%)
2 (10%)
0 (0%)
24 (34%)
10 (14%)
29 (41%)
8 (11%)
0.001
PaO2/FiO2 at ETI, mean±SD 156±178 101±64 107±52 169±157 0.01
Characteristics
Univariate analysis Multivariate analysis
Coefficient [95%CI] P value Coefficient [95%CI] P value
Age -0.04 [-0.13-0.04] 0.29
Female gender 0 [-2.67;2.67] 1.00
SAPSII -0.09 [-0.15;-0.03] 0.005 -0.06 [-0.11;-0.005] 0.03
SOFA score -0.3 [-0.66;0.06] 0.1
Baseline SpO2 0.9 [0.71;1.09] <0.001 0.91 [0.71;1.10] <0.001
Duration of preoxygenation, min
<5
≥5 and <9
≥9
1
-2 [-5.07;1.07]
-1 [-3.88;1.88]
0.43
Duration of ETIa 0 [-0.53;0.53] 1
Number of laryngoscopies
1
2
3 or more
1
-5 [-8.45;-1.55]
1 [-4.44;6.44]
0.01
1
-4.79 [-7.86;-1.73]
1.21 [-3.64;6.06]
0.01
Main reason for intubation
Neurological
Respiratory
Cardiovascular
Other
1
-7 [-10.41;-3.59]
-4 [-7.59;-0.41]
-1 [-6.13;4.13]
0.001
Use of a tracheal tube introducer 1 [-2.99;4.99] 0.62
Successful first-pass ETI by a non-
expert
2 [-0.74;4.74] 0.15
Preoxygenation device
BVM
NIV
HFNO
NRB
1
-4 [-7.31;-0.69]
-3 [-8.4;2.4]
0 [-3.29;3.29]
0.08
1
-2.48 [-5.28;-0.32]
-2.66 [-7.18;1.85]
-1.23 [-4.01;1.54]
0.29
Bailly. Under review.
Régression médiane SpO2 minimale
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aOR [IC95%] P value
Baseline SpO2 0.72 [0.65-0.80] <0.001
Preoxygenation device
Bag valve mask
Non-invasive ventilation
High-flow nasal oxygen
Non-rebreathing mask
1
0.10 [0.01-0.80]
5.75 [1.15-28.76]
1.10 [0.25-4.92]
0.02
Bailly. R2.
Patient ayant un épisode SpO2<90% durant la procédure
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Exposition
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Et si c’est déjà prévu…
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INTUBATION NASALE
Bloc opératoire
INTUBATION ORALE
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Intubation « difficile » inattendue
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Quels outils ?
Stylet
Bougie
VidéolaryngoscopeScalpel/CRICO/FONA
Masque laryngé
Laryngoscopie 1 Laryngoscopie 2 Laryngoscopie n
BURP
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No difference
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POGO Score
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POGO Score
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POGO Score
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Arulkumaran, N., et al., Videolaryngoscopy versus direct laryngoscopy for emergency orotracheal intubation outside the operating room: a systematic review and meta-analysis. Br J Anaesth, 2018. 120(4): p. 712-724.
Jiang, J., et al., Video laryngoscopy does not improve the intubation outcomes in emergency and critical patients – a systematic review and meta-analysis of randomized controlled trials. Critical Care, 2017. 21(1): p. 288.
Bhattacharjee, S., S. Maitra, and D.K. Baidya, A comparison between video laryngoscopy and direct laryngoscopy for endotracheal intubation in the emergency department: A meta-analysis of randomized controlled trials. J Clin Anesth, 2018. 47: p. 21-26.
Gao, Y.X., et al., Video versus direct laryngoscopy on successful first-pass endotracheal intubation in ICU patients. World J Emerg Med, 2018. 9(2): p. 99-104.
Huang, H.B., et al., Video Laryngoscopy for Endotracheal Intubation of Critically Ill Adults: A Systemic Review and Meta-Analysis. Chest, 2017. 152(3): p. 510-517.
Savino, P.B., et al., Direct Versus Video Laryngoscopy for Prehospital Intubation: A Systematic Review and Meta-analysis.Acad Emerg Med, 2017. 24(8): p. 1018-1026.
Zhao, B.C., T.Y. Huang, and K.X. Liu, Video laryngoscopy for ICU intubation: a meta-analysis of randomised trials. Intensive Care Med, 2017. 43(6): p. 947-948.
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Des nouveautés tous les jours…
Macintosh Like
- McGrath Mac
Difficult intubation
- Glidescope
With channel blade
- Airtaq- KingVision- AWS 200C-MAC
APA
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Quelques minutes plus tard…
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Before intubation
During intubation
After intubation
PetCO2 confirmation
Vt set at 6 mL/kg IBW
Chest radiography
Screening for difficult intubation: MACOCHA score
Sniffing or ramping position
Fluid loading, early norepinephrine infusion
Material (suction, PetCO2, difficult-intubation trolley)
Preoxygenation
- Hypoxemia: NIV
- No hypoxemia: HFNC, NRM, BVM
Induction
- Ketamine, Etomidate
- Succinylcholine, Rocuronium
Direct laryngoscopy (metal blade)
Face mask
ventilation
easy
Face mask
ventilation
difficult
Bougie + VideolaryngoscopeSupraglottic
device
(fiberoptic
Intubation)
CICO
Awake VL
Awake fiberoptic endoscopy
AND SpO2≥92%OR SpO2<92%
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« Take Away Message »
• Prendre quelques minutes (secondes) pour évaluer la situation
• Optimiser la pré-oxygénation et la première laryngoscopie
• Avoir des outils (mais pas trop) en cas d’intubation difficile• Mandrin long > stylet• Masque facial• Vidéolaryngoscope • Masque laryngé• « FONA » kit
Questions, remarques à: @JBLascarrou
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Questions, remarques à: @JBLascarrou ou [email protected]
Max 20 patients / 8 semaines / note information
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3472 patients
0.55 inhalation