2014 annual report - advancing immunotherapy research

2014 Annual Report

BREAKINGTHROUGH

01 From CRI’s Leadership

02 Breaking Through

04 Postdoctoral Program

06 Clinic and Laboratory Integration Program

08 Clinical Accelerator

10 Thought Leadership

12 Patient Education

14 Public Awareness

16 Awards and Honors

18 Fiscal Year 2014 Grants and Awards

29 Donors and Supporters

45 Financials

47 Stewards of the Organization

55 Giving to the Cancer Research Institute

OUR MISSION:SAVE MORE LIVES WITH CANCER IMMUNOTHERAPYEstablished in 1953, the Cancer Research Institute (CRI) is the world’s only nonprofit organization dedicated exclusively to saving cancer patients’ lives by fueling the development of smarter, more effective treatments that mobilize our immune defenses against all forms of cancer. CRI supports the most innovative research of young scientists, invests in clinical studies of encouraging new treatments, and unites the efforts of the field’s leaders worldwide. With this work, CRI is turning our own immune system into a powerful weapon against cancer.

Kunle Odunsi, M.D., Ph.D., at Roswell Park Cancer Institute Member, CRI Scientific Advisory Council

This past year was one of many breakthroughs for the Cancer Research Institute (CRI). Science magazine

named cancer immunotherapy the “Breakthrough of the Year,” catapulting the work that CRI does into the spotlight. It was also the year that several immunotherapies pioneered by CRI scientists received “Breakthrough Therapy” status from the FDA, paving the way for important new drug approvals. In September of 2014, U.S. regulators approved Merck’s drug Keytruda® (pembrolizumab) for the treatment of melanoma, making it the first PD-1 checkpoint inhibitor to receive FDA approval and the third immunotherapy to be approved in just the past four years.

Institutionally, CRI had a breakthrough year, as well. We devoted $22 million to our programs—more than we

ever have at one time before. We launched a new patient website, TheAnswerToCancer.org, designed to educate patients and caregivers about cancer immunotherapy. We celebrated our second annual Cancer Immunotherapy Month, mobilizing individuals and companies across the world to participate in our education and awareness activities. And our Clinical Accelerator program is spearheading several important clinical trials that are bringing lifesaving immunotherapies to patients faster.

None of this would be possible without the generous support of our donors, who sustain our work and make tangible our vision of a world free from the fear of cancer. On behalf of our staff, our scientists, and our patients, thank you for all that you do to help CRI pursue its mission to conquer cancer within our lifetimes.

FROM CRI’S

LEADERSHIP

James P. Allison, Ph.D.Director, Scientific Advisory Council

Jill O’Donnell-Tormey, Ph.D.CEO and Director of Scientific Affairs

John B. FitzgibbonsCo-Chairman of the Board

Paul C. ShiverickCo-Chairman of the Board

CANCER RESEARCH INSTITUTE 2014 ANNUAL REPORT 1

Cancer immunotherapy offers the greatest hope of transforming cancer treatment in our lifetimes.Jill O’Donnell-Tormey, Ph.D., CEO and Director of Scientific Affairs

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For this year’s annual report, we chose the theme “Breaking Through,” in recognition

of the tremendous progress being made in the field of cancer immunotherapy. We at the Cancer Research Institute (CRI) know that the current state of optimism about immune-based treatments for cancer would not have been possible without the decades of research that came before. We also know that future advances will depend upon continued financial support of the entire research spectrum, from basic science, to translational research, to clinical trials. With its more than 60 years of funding research to understand the immune system and how it can be harnessed to conquer cancer, CRI is leading the way and ushering in a new era when patients, with all types of cancer, can be treated and one day cured with immunotherapy.

Dendritic cells (green) use their spiny tendrils to present antigens to T cells (red). Photo courtesy of Olivier Schwartz, Ph.D., Pasteur Institute

BREAKINGTHROUGH

The CRI-IRVINGTON POSTDOCTORAL FELLOWSHIP PROGRAM, established in 1971, is CRI’s longest-running continuous program. Fellowships provide up to $164,500 over three years to support young immunologists and cancer immunologists studying at top universities around the world.

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Immune EvasionAs cancer begins to develop, our immune system tries to eliminate it. However, immune cells are often unable to prevent cancer development because their activity is inhibited in several ways, including by checkpoints that “put the brakes” on the immune response, and by regulatory cells that tell the immune system to “stand down.” Cancer cells then escape detection and destruction by the immune system and grow into tumors. CRI postdoctoral fellows are exploring how immune evasion occurs and how it can be overcome, with the hope of improving the effectiveness of immunotherapies.

CRI postdocs pursue tomorrow’s breakthroughs today

BASICS AT THE

BENCH

In medicine, the most important breakthroughs usually come from research aimed at understanding fundamental

biological mechanisms. CRI is currently supporting the basic laboratory research of 90 postdoctoral fellows, with the understanding that tomorrow’s cures will be built on the solid foundation of today’s basic discoveries.

26 new grants

$4.3 million awarded

For a complete list of all 90 postdoctoral fellows, go to page 19.

01 Noah W. Palm, Ph.D., and Nicola Gagliani, Ph.D.02 Matthew Gubin, Ph.D.03 Stefani Spranger, Ph.D.04 Chunyu Jin, Ph.D.

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Optimizing TherapeuticsNumerous CRI postdoctoral fellows are conducting research into improving the effectiveness of existing immunotherapies and understanding the mechanisms by which they work. From uncovering new cancer antigens that can be used in therapeutic vaccines, to developing new targets for genetically engineered T cells, to understanding how checkpoint inhibitor antibodies work to stimulate the immune response, CRI postdoctoral fellows are bringing basic research to bear on topics of great clinical importance.

Inflammation, Microbes, and Cancer Chronic inflammation is believed to promote the development of several types of cancer, including colorectal, liver, bladder, and lung cancers. CRI postdoctoral fellows are pursuing research aimed at understanding the link between inflammation and cancer progression, including the role that bacteria and viruses may play in this process. By finding ways to combat chronic inflammation, scientists may one day be able to control the development of inflammation-induced cancer, or prevent it altogether.

Watch the VideoGut Responses: Inflammation, Microbes, and Cancerwww.bit.ly/gut-responses

The Cancer Research Institute has been very wise in putting the majority of its money into people who will develop new ideas.James Watson, Ph.D., co-discoverer of the structure of DNA and CRI grantee

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The CLINIC AND LABORATORY INTEGRATION PROGRAM (CLIP) supports scientists who are exploring clinically relevant questions aimed at improving the effectiveness of cancer immunotherapies. CLIP grants provide up to $200,000 over two years.

Where other funding agencies fear to tread, CLIP creates a bridge

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12 new grants

$2.4 million awarded

“ I definitely believe that the work I’m doing is going to benefit cancer patients. Ryan M. Teague, Ph.D., CLIP Investigator

Some of the most exciting questions in tumor immunology today are ones being pursued at the

interface between basic and clinical research. Yet few funding agencies focus on this translational research. CRI’s Clinic and Laboratory Integration Program (CLIP) was launched in 2011 to serve this unmet need. Current CLIP scientists are pursuing novel therapeutic strategies informed by the cutting edge of both laboratory and clinical research. Their projects are bringing innovative therapies for patients closer to reality.

BEDSIDE

For a complete list of all 24 CLIP investigators, go to page 24.

Pulling the Rug Out from Under TumorsEllen Puré, Ph.D.Genentech InvestigatorUniversity of PennsylvaniaSchool of Veterinary MedicinePhiladelphia, PA

Most conventional cancer therapies directly target cancer cells. In recent years, researchers have learned that the cells surrounding a tumor are just as important. Ellen Puré, Ph.D., is using genetically engineered immune cells to kill the cancer-supporting “stromal” cells surrounding tumors. Called chimeric antigen receptor (CAR) T cells, these engineered cells contain a protein receptor that turns T cells into cancer fighters. Dr. Puré has shown that these CAR T cells can inhibit the growth of lung tumors in mice. They are now exploring whether this immunotherapy can enhance the effectiveness of conventional therapies like chemotherapy and radiation.

Beta-Blocker Therapy for Breast CancerMing Li, Ph.D.Memorial Sloan Kettering Cancer CenterNew York, NY

Suppression of the immune system by cancer cells is believed to play an important role in cancer progression. Ming Li, Ph.D., is studying the immunosuppressive pathway that is activated in tumor-associated immune cells in breast cancer models. This pathway is also the target of beta blockers, which are used to treat high blood pressure and which have been associated with increased survival among breast cancer patients. Dr. Li is investigating whether beta blockers target T cells to control breast tumor development, and is also working to understand how this pathway regulates T cell responses to tumors, which may reveal novel targets for the immunotherapy of breast cancer.

When Cancer Starves the Immune SystemJeffrey Rathmell, Ph.D.Wade F.B. Thompson InvestigatorDuke University Medical CenterDurham, NC

Researchers have known for a long time that cancer cells compete with normal cells for energy and nutrients. Jeffrey Rathmell, Ph.D., is working to understand how this competition suppresses the immune system’s ability to fight cancer. In a model of kidney cancer, he has found that cancer cells starve immune cells of important nutrients such as glucose and amino acids, leaving them unable to marshal an effective immune response and altering their function. His work also suggests that therapies designed to block immune checkpoints, such as anti-PD-1 antibodies, may act in part by shifting this metabolic competition back in favor of immune cells.


From brilliant scientists to innovative drugs, CRI’s Clinical Accelerator brings the right ingredients together

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The CLINICAL ACCELERATOR is a venture philanthropy program designed to speed the development of cancer immunotherapies by facilitating research collaboration between biopharma companies and academic cancer researchers. The program aims to identify and kick-start the development of new combination treatments using the most promising drugs.

30+ drugs accessed

$12 million awarded

Key to the success of the program is an innovative, collaborative model: CRI partners with leading biopharma companies to gain access to their drugs; CRI then provides nonprofit investment capital to help fund clinical trials of drug combinations that scientists in our clinical network think are most promising, while our partner, Ludwig Cancer Research, provides clinical trial management support. Industry benefits by getting more shots on goal, CRI scientists benefit by gaining research knowledge to inform future trials, and patients benefit by getting access to better immunotherapies sooner.

Scientists increasingly recognize that the cancer treatments of tomorrow will be made up of combinations of different

drugs that work in complementary fashion. At the same time, it has become clear that existing models of drug development are not well suited to testing these combinations in a smart and coordinated fashion. Through its novel Clinical Accelerator program, CRI is enabling the strategic partnerships and drug combinations needed to generate the next cancer breakthroughs.

For a complete list of all CRI-funded clinical trials, go to page 25.

To date, CRI has announced collaborations with seven biopharma companies, including MedImmune/AstraZeneca, Immune Design, CureVac, and VentiRx. CRI investigators now have access to a “menu” of roughly 30 drugs from more than 15 companies, including formal and informal partnerships.

The Clinical Accelerator is currently supporting over 20 clinical trials, including four that have already opened, six that are in planning stages, and another 12 for which it has supplied drugs. All of these studies test novel combinations of immunotherapies for patients with a variety of different cancers, including melanoma, cervical, colorectal, head and neck, kidney, and lung cancers. Immunotherapies being studied include several checkpoint inhibitors (anti-PD-L1, anti-CTLA-4) and immune modulators (anti-GITR, TLR3 agonist), as well as vaccines targeting cancer-specific antigens. Just this past year, CRI committed funding to two new clinical trials—one for patients with advanced brain cancer, and another for patients with advanced ovarian cancer. These groundbreaking clinical trials are critical to designing better immunotherapies for patients, and Clinical Accelerator is making them happen faster.

“The Clinical Accelerator provides significant and immediate benefits to patients, researchers, and industry. It’s is a win-win-win situation.Adam Kolom, Managing Director

Saving more livesUnlike conventional therapies like chemotherapy and radiation, which typically only temporarily extend patient lives, immunotherapies are providing some patients with durable remissions. Combining immunotherapies has the potential to save more lives.

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For more than 20 years, CRI has been convening scientists to discuss immunotherapy

MEETING OF

THE MINDS

Established in 1993, CRI’s annual scientific symposium focuses on progress in cancer immunology and immunotherapy. The theme of this past year’s meeting was “Dynamics of Host-Tumor Interaction,” and brought more than 325 scientists from around the world to New York City for three days last October.

Among the many topics explored were the role of chronic inflammation in promoting cancer, the function of the tumor stroma in promoting immune evasion, and the role of bacteria in shaping responses to cancer treatment.

The symposium began with the inaugural William B. Coley lecture, delivered by Michael Karin, Ph.D., winner of the 2013 William B. Coley Award. In his lecture, Dr. Karin discussed the role of inflammation and how it can both promote and

combat cancer. The meeting also included a poster session with presentations by 110 graduate students, postdoctoral fellows, and other investigators, five of whom were invited to deliver a lecture during the general session.

Since 2002, the Cancer Immunotherapy Consortium (CIC) has been working to make immunotherapy the standard-of-care in oncology. In 2013, the CIC was reconceived as a “think tank” devoted to tackling the most urgent matters in bringing new immune-based treatment to the clinic and through regulatory approval. Each year, one topic will be addressed and a white paper produced. The topic chosen for 2014 was the development of surrogate endpoints for cancer immunotherapy.

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The ANNUAL INTERNATIONAL CANCER IMMUNOTHERAPY SYMPOSIUM is an annual scientific meeting devoted to exploring the latest research in cancer immunology and immunotherapy, and is attended by both basic scientists and clinicians.

The CANCER IMMUNOTHERAPY CONSORTIUM (CIC) convenes the major stakeholders from academia, industry, regulatory bodies, and patient groups who share a common interest in promoting immunotherapy research and development.

Getting scientists together in one place to meet and discuss new ideas has always been a valuable part of

the scientific enterprise—one no less important today in our world of hyper-communication.

Watch the VideoPutting out the Fire: Reducing Cancer-Causing Inflammation, with Dr. Michael Karin www.bit.ly/cancer-inflammation

“[The CRI symposium is] the milestone around which we in the field of tumor immunology and immunotherapy now mark our progress. Steven A. Rosenberg, M.D., Ph.D., National Cancer Institute

01 Milton W., leukemia survivor 02 KayEllen G., ovarian cancer survivor, and daughter, Nicole

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THEANSWERTOCANCER.ORG

NEW WEBSITEThe first-of-its-kind cancer immunotherapy resource for patients and caregivers

As major advances in cancer immunotherapy begin to alter the landscape of cancer treatment,

patients facing a cancer diagnosis need to be aware of immunotherapy as a potential treatment option. On June 1, 2014, CRI launched a new website designed specifically for cancer patients and caregivers interested in learning about cancer immunotherapy.

TheAnswerToCancer.org seeks to engage, educate, and empower patients and their loved ones to learn more about cancer immunotherapy as a treatment option across numerous tumor types. The website provides an accessible overview of the science behind cancer immunotherapy, detailed information about cancer immunotherapy clinical trials, and voices from the cancer immunotherapy community.

TheAnswerToCancer.org is supported through a charitable donation from Bristol-Myers Squibb.

Visit www.theanswertocancer.org to learn more.

When I was dealing with prostate cancer and realized there were treatments designed to help boost the immune system so that it could detect the disease, I was taken by that whole concept.Joe B., Prostate Cancer Survivor

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Some highlights of the month-long campaign include:

• “30 Days, 30 Stories” of patients sharing their experiences with lifesaving immunotherapy.

• More than half a million people turned to social media on June 6 for #WhiteOutCancer Day.

• A Twitter Chat co-sponsored by CRI, TIME magazine, Mayo Clinic, and the American Association for Cancer Research (AACR) reached 16.5 million people.

• A series of free weekly educational webinars helped people learn about melanoma, lung cancer, prostate cancer, bladder cancer, kidney cancer, and ovarian cancer and about how groundbreaking research in immunotherapy is transforming their treatment. Past webinars can be viewed at www.bit.ly/CRIwebinars.

• Sponsors and supporters for the month included members of the biotech and biopharmaceutical industry, 1-800-flowers.com, AACR, Stand Up To Cancer, and many others. See a complete list of sponsors and supporters at www.bit.ly/2014CIMsupporters.

GETTING THE

WORD OUT

This past June, CRI celebrated its second annual Cancer Immunotherapy Month™ to raise awareness of

immunotherapy and its potential to transform cancer treatment in our lifetimes. It exceeded expectations, raising more than $230,000 for cancer research.

Cancer Research Institute celebrates second annual Cancer Immunotherapy Month™

01 Sandra Coudert Graham’s twins 02 NASDAQ Closing Bell Ceremony03 Billi Bob, a feline supporter04 Carley and Laura Rutledge05 Peregrine Pharmaceuticals

06 Roswell Park Cancer Institute07 Trilogy Lacrosse08 CRI staff with PBS NewsHour correspondent Paul Solman

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“ It is my firm belief...that the end of cancer is actually closer at hand than anyone outside of this room even realizes.Sean Parker, Serial Tech Entrepreneur and Philanthropist

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SEach year, CRI honors those individuals who have made important contributions to the field of cancer immunotherapy

RECOGNIZING EXCELLENCE

WILLIAM B. COLEY AWARD FOR DISTINGUISHED RESEARCH IN BASIC AND TUMOR IMMUNOLOGY

Michael B. Karin, Ph.D. Professor of Pharmacology and Pathology University of California, San Diego

FREDERICK W. ALT AWARD FOR NEW DISCOVERIES IN IMMUNOLOGY

Jill O’Donnell-Tormey, Ph.D. CEO and Director of Scientific Affairs Cancer Research Institute

AACR-CRI LLOYD J. OLD AWARD IN CANCER IMMUNOLOGY

Robert D. Schreiber, Ph.D. Alumni Endowed Professor of Pathology and Immunology Washington University School of Medicine

OLIVER R. GRACE AWARD FOR DISTINGUISHED SERVICE IN ADVANCING CANCER RESEARCH

Bahija Jallal, Ph.D. Executive Vice President, AstraZeneca Head, MedImmune

Sean Parker Serial Tech Entrepreneur and Philanthropist

01 Honorees, presenters, and co-chairmen 02 Glenn Dranoff, M.D., and Michael B. Karin, Ph.D. 03 Carl H. June, M.D., with leukemia survivor Emily Whitehead and her parents, Kari and Tom

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Watch the award videos atwww.bit.ly/2014CRIawards

In fiscal year 2014 (July 1, 2013, to June 30, 2014), CRI awarded more than $19 million for cancer immunology research and cancer immunotherapy clinical development.*Denotes grants newly awarded in fiscal year 2014. All others are active grants awarded in previous years.

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SStudent Training and Research in Tumor Immunology (STaRT) ProgramTwo-year awards that attract bright young minds to rewarding careers as cancer immunologists by funding graduate studies in tumor immunology at top universities.

Thomas Chia Ting FungPerelman School of Medicine at the University of Pennsylvania, Philadelphia, PARole of innate lymphoid cell-controlled intestinal barrier function in hepatocellular carcinoma

Alexandria HuynhMassachusetts General Hospital, Boston, MAThe role of PTEN in regulatory T cell stability and immune surveillance

Jenny KaroMemorial Sloan Kettering Cancer Center, New York, NYElucidating the regulatory role of CTLA-4 on natural killer cell responses

Albert LoPerelman School of Medicine at the University of Pennsylvania, Philadelphia, PARegulation of inflammatory and immune response to pancreatic cancer by FAP+ stromal cells

Thornton William ThompsonUniversity of California, Berkeley, Berkeley, CAThe role of oncogene-induced senescence in promoting anti-tumor immune responses

Predoctoral Emphasis Pathways in Tumor ImmunologyFour-year awards to universities to support establishment and maintenance of tumor immunology training courses for graduate students.

Harvard Medical School, Boston, MADirectors: Glenn Dranoff, M.D., and Michael Carroll, Ph.D.

Johns Hopkins University School of Medicine, Baltimore, MDDirector: Charles G. Drake, M.D., Ph.D.

QIMR Berghofer Medical Research Institute, Queensland, AustraliaDirector: Mark J. Smyth, Ph.D.

University of Colorado, Denver, CODirectors: John Kappler, Ph.D., and Philippa Marrack, Ph.D.

University of Washington School of Medicine, Seattle, WADirector: Philip D. Greenberg, M.D.

Washington University School of Medicine, St. Louis, MODirector: Robert D. Schreiber, Ph.D.

Weill Cornell Medical College, New York, NYDirectors: Alexander Y. Rudensky, Ph.D., and Carl F. Nathan, M.D.

Immunology/Tumor Immunology Training Course

Lomonosov Moscow State University, Moscow, RussiaCourse Coordinator: Sergei A. Nedospasov, Ph.D., D.Sc.*The Lloyd J. Old Advanced Training Program in Immunology and Oncoimmunology

CRI-Irvington Postdoctoral Fellowship ProgramThree-year awards that further the career development and advanced laboratory research of promising postdoctoral fellows working under the mentorship of world-class immunologists and tumor immunologists.

Antibody Structure and Diversity

Jiazhi Hu, Ph.D.*Boston Children’s Hospital, Boston, MAMechanisms that target AID for antibody gene diversification and for oncogenic chromosomal translocationsRobertson Foundation Fellow

Feilong Meng, Ph.D.Boston Children’s Hospital, Boston, MARole of co-factors in targeting activation-induced cytidine deaminase activity during class switch recombination and somatic hypermutation

Qi Qiao, Ph.D.Boston Children’s Hospital, Boston, MAMechanistic elucidation of activation-induced deaminase (AID) in immunity and cancer

Beth M. Stadtmueller, Ph.D.California Institute of Technology, Pasadena, CAThe structural and molecular basis of polymeric IgA function in mucosal immunity and associated cancers

Leng Siew Yeap, Ph.D.Boston Children’s Hospital, Boston, MAMechanisms by which DNA sequence influence AID targeting in antibody diversity and B lymphocyte cancer

Tangsheng Yi, Ph.D.University of California, San Francisco, San Francisco, CARole of EBI2 and its oxysterol ligands in adaptive immunity

Hye Suk Yoon, Ph.D.Boston Children’s Hospital, Boston, MAElucidation of V(D)J recombination control elements in the IgH locus

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CRI Scientific Advisory Council member Lisa M. Coussens, Ph.D., with postdoctoral fellow at Oregon Health & Science University

Roy Louis Maute, Ph.D., CRI postdoctoral fellow at Stanford University School of Medicine


Mo Xu, Ph.D.NYU Langone Medical Center, New York, NYIntestinal microbiota-induced Th17 responses in systemic inflammatory diseaseMargaret Dammann Eisner Fellow

Zhenyu Zhong, Ph.D.*University of California, San Diego, La Jolla, CAIdentification of key immune homeostatic regulators that control obesity-induced liver inflammation and disease

Joshua W. Ziel, Ph.D.NYU Langone Medical Center, New York, NYCommensal control of intestinal Th17: Treg balance during homeostasis and carcinogenesis

Novel Therapeutics

Evelyn Dixit, Ph.D.*Boston Children’s Hospital, Boston, MASpatiotemporal regulation of RIG-I paves the way for novel cancer immunotherapies

Haidong Tang, Ph.D.*University of Chicago, Chicago, ILTumor-specific LIGHT targeting for cancer immunotherapy

Li Tang, Ph.D.Massachusetts Institute of Technology, Cambridge, MAT lymphocyte engineering with interleukin 2-silica nanocapsules for targeted cancer therapy

John T. Wilson, Ph.D.University of Washington School of Medicine, Seattle, WAA new class of multifunctional smart polymers for cancer vaccine delivery

Jason Hudak, Ph.D.*Harvard Medical School, Boston, MAUnderstanding microbial sensing in colorectal cancer using bioorthogonal chemistry

Chunyu Jin, Ph.D.University of California, San Diego, La Jolla, CAGenomic approaches to roles of GPS2 in innate immunology dependent events in prostate cancer

Kiwook Kim, Ph.D.Yale School of Medicine, New Haven, CT GBP5-NOD2 interactions in gastrointestinal host defense, colitis, and colon cancer

Noah Wolcott Palm, Ph.D.Yale School of Medicine, New Haven, CT Role of helminth infections and the commensal microbiota in intestinal inflammation

April Price, Ph.D.University of California, Berkeley, Berkeley, CAExpression and function of Toll-like receptors in intestinal epithelial cells

Rajesh R. Rao, Ph.D.Dana-Farber Cancer Institute, Boston, MANovel exercise-induced myokines as modulators of inflammation and defense against chronic diseases

Nathan R. West, Ph.D.University of Oxford, Oxford, United KingdomAnalysis of novel susceptibility genes in chronic intestinal inflammation and colon cancer

Justin J. Taylor, Ph.D.University of Minnesota, Minneapolis, MNDirect tracking of vaccine-specific B cells from naïve precursors

Inflammation, Microbes, Cancer

Michael C. Abt, Ph.D.*Memorial Sloan Kettering Cancer Center, New York, NYInnate immune regulation of C. difficile-driven inflammation

Maureen Ann Cox, Ph.D.University Health Network, Toronto, CanadaInvestigation of the role of HMGB1 in asbestos-driven inflammation and mesothelioma development

Liron David, Ph.D.Boston Children’s Hospital, Boston, MAMolecular elucidation of the CBM complex in NFκB activation by antigen receptors

Timothy Eitas, Ph.D.University of North Carolina at Chapel Hill, Chapel Hill, NCRegulation of colitis-associated cancer by NLRX1

Nicola Gagliani, Ph.D.Yale School of Medicine, New Haven, CT Targeting Th17 cell plasticity to control colorectal cancer developmentDr. Keith Landesman Memorial Fellow

Wendy Jia Men Huang, Ph.D.NYU Langone Medical Center, New York, NYMolecular mechanisms underlying SFB-Th17 induction and intestinal tumor pathogenesisMargaret Dammann Eisner Fellow

James A. Harker, Ph.D.University of California, San Diego, La Jolla, CAThe role of gp130 associated cytokines in chronic viral infection

Alice O. Kamphorst, Ph.D.Emory University, Atlanta, GARole of dendritic cells in T cell dysfunction during chronic viral infections

Mickael Mathieu Menager, Ph.D.NYU Langone Medical Center, New York, NYMolecular mechanisms of dendritic cell-mediated transfer of HIV-1 to CD4+ T lymphocytes

James B. Munro, Ph.D.Yale School of Medicine, New Haven, CT Single-molecule imaging of immune evasion by HIV Env

Blaise Ndjamen, Ph.D.California Institute of Technology, Pasadena, CAA model system to investigate antibody bipolar bridging mediated by gE-gI, a Herpes virus Fc receptor

Lisa C. Osborne, Ph.D.Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PARegulation of protective immunity following enteric viral infectionEdmond J. Safra Fellow

Read Pukkila-Worley, M.D.Massachusetts General Hospital, Boston, MAA novel live-animal system for the characterization of anti-fungal innate immunity

Nicole L. Sullivan, Ph.D.Emory University, Atlanta, GADevelopment of human CD4+ T cell memory against viruses

Hyang-Mi Lee, Ph.D.*University of California, San Diego, La Jolla, CATargeting regulatory T cell-mediated regulation of IFNγ-driven anti-tumor immunity

Roy Louis Maute, Ph.D.*Stanford University School of Medicine, Stanford, CACharacterization of the MHC/LILRB signaling axis as an immunotherapeutic target in cancer

Ying Zheng, Ph.D.Johns Hopkins University School of Medicine, Baltimore, MDThe role of HIF-1 in adaptive T cell responses to cancerDonald J. Gogel Fellow

Infectious Disease and Autoimmunity

Tessa Bergsbaken, Ph.D.University of Washington School of Medicine, Seattle, WAA T cell intrinsic role for Caspase-1 in the immune response

Jonathan M. Clingan, Ph.D.*University of Washington School of Medicine, Seattle, WAIntegration of transcriptional and translational control of the anti-viral response

Pu Gao, Ph.D.*Memorial Sloan Kettering Cancer Center, New York, NYStructural and functional studies of cytosolic DNA sensing pathwayRobertson Foundation Fellow

Elizabeth Gray, Ph.D.University of Washington School of Medicine, Seattle, WAFunctional analysis of the interferon stimulatory DNA pathway

Paola A. Betancur, Ph.D.Stanford University School of Medicine, Stanford, CAIn search of the gene regulatory circuitry responsible for the transcriptional upregulation of CD47, the “don’t eat me” signal in cancer cells

Juan R. Cubillos-Ruiz, Ph.D.Weill Cornell Medical College, New York, NYXBP1 as a key regulator of dendritic cell pro-tumoral activity

Yongqiang Feng, Ph.D.Memorial Sloan Kettering Cancer Center, New York, NYRole of conserved non-coding elements of Foxp3 in regulatory T cell development and functionBristol-Myers Squibb Fellow

Ross B. Fulton, Ph.D.University of Minnesota, Minneapolis, MNNaïve CD8+ T cells differ in their ability to respond to tumor-associated antigen

Georg A.J. Gasteiger, M.D.Memorial Sloan Kettering Cancer Center, New York, NYRegulation of cytotoxic killer cells by Foxp3+ regulatory T cells

Yenkel Grinberg-Bleyer, Ph.D.Columbia University Medical Center, New York, NYTesting the role of NFκB in tumor immunity through its effect on regulatory T cells

Sudha Kumari, Ph.D.NYU Langone Medical Center, New York, NYCharacterization of a novel molecular compartment modulating regulatory T cell function

Gene Expression and Development

Bradley Wayne Blaser, M.D., Ph.D.*Boston Children’s Hospital, Boston, MAImmunologic regulation of hematopoietic stem cell engraftment

Jing-Ping Hsin, Ph.D.*Memorial Sloan Kettering Cancer Center, New York, NYThe effects of cellular context on miR-155 mediated regulation of gene expressionYoung Philanthropists Council Fellow

Shengdong Ke, Ph.D.The Rockefeller University, New York, NYRNA epigenetic HITS-CLIP: A new approach to understanding leukemia/lymphoma

You Jeong Lee, M.D., Ph.D.University of Minnesota, Minneapolis, MNIL-4 produced by iNKT cells directs the development of memory CD8+ T cells

Chan-Wang J. Lio, Ph.D.La Jolla Institute for Allergy and Immunology, La Jolla, CARole of long non-coding RNAs in the development of T cell leukemia

Sara Trifari, Ph.D.La Jolla Institute for Allergy and Immunology, La Jolla, CAIdentification and functional characterization of novel epigenetic and transcriptional regulators of CD8+ T cell differentiation

Ageliki Tsagaratou, Ph.D.La Jolla Institute for Allergy and Immunology, La Jolla, CADissecting the role of 5 hydroxymethylcytosine in T cell development, homeostasis, and function

Yina Zhu, Ph.D.University of California, San Diego, La Jolla, CAMechanisms that underpin the sequestration of the tumor suppressor ebf1 at the nuclear lamina

Immune Evasion

Michele Ardolino, Ph.D.University of California, Berkeley, Berkeley, CAMHC-deficient tumors inactivate infiltrating NK cells: A new target for cancer immunotherapy

CRI postdoctoral fellow Juan R. Cubillos-Ruiz, Ph.D., with Stanley Adoro, Ph.D., at Weill Cornell Medical College


Brian R. Graziano, Ph.D.*University of California, San Francisco, San Francisco, CAUsing optogenetics to probe the in vivo biochemistry of cell movement

Jesse Green, Ph.D.Memorial Sloan Kettering Cancer Center, New York, NYInteractions of regulatory T cells with the tumor endothelium and effects on the tumor microenvironmentSamuel and Ruth Engelberg Fellow

Corrie Ann Painter, Ph.D.University of Massachusetts Medical School, Worcester, MAInvestigating the adaptive immune response to melanoma in the zebrafish Danio rerio

Edward W. Roberts, Ph.D.*University of California, San Francisco, San Francisco, CALifespan, fate, and function of immune cells educated in primary tumors

Stefani Spranger, Ph.D.*University of Chicago, Chicago, ILThe role of tumor-intrinsic oncogene alterations in immune evasion of melanoma

Investigator AwardsFour-year bridging grants to assistant professors undertaking their first independent investigations in basic and tumor immunology, designed to provide flexibility and stability while they establish their laboratories.

Wendy S. Garrett, M.D., Ph.D.Harvard School of Public Health, Boston, MAThe role of inflammatory monocytes and the gut microbiota in colorectal cancer

Dimitrios Iliopoulos, Ph.D.UCLA Medical Center, Los Angeles, CAIdentification of novel molecular circuits that link inflammation to cancer

Estela P. Jacinto, Ph.D.UMDNJ-RWJ Medical School, Piscataway, NJmTOR targets in T lymphocyte development

Jennifer M. Lund-Friesen, Ph.D.Fred Hutchinson Cancer Research Center, Seattle, WARegulatory T cell modulation of immunity to mucosal viral infections

Qi Wang, Ph.D.University of California, Berkeley, Berkeley, CAMolecular mechanisms of T cell activation by the tyrosine kinase Lck and ZAP-70

Tumor Microenvironment

Alexandra Boussommier, Ph.D.*Massachusetts Institute of Technology, Cambridge, MACharacterizing the role of macrophages in breast cancer cell extravasation and recolonization in organ-specific 3D microfluidic models

Hsin Chen, Ph.D.*University of California, San Francisco, San Francisco, CAMechanisms controlling lymphocyte retention in and egress from tissue

Viviana Cremasco, Ph.D.Dana-Farber Cancer Institute, Boston, MATargeted disruption of tumor matrix architecture to restore cancer immunosurveillance

Optimizing Therapies

Margaret Callahan, M.D., Ph.D.Memorial Sloan Kettering Cancer Center, New York, NYImmunologic effects of BRAF inhibitors: Towards the rational development of multi-modality therapy for advanced melanomaLloyd J. Old Memorial Fellow

Carmen Gerlach, Ph.D.*Harvard Medical School, Boston, MADifferentiation, function, and dynamic behavior of transitional memory cells (TTM): A novel subset of CD8+ memory T cells

Matthew M. Gubin, Ph.D.*Washington University School of Medicine, St. Louis, MOUsing genomics to identify targets of checkpoint blockade cancer treatment and to identify optimal target antigens for vaccination

Jin-Hwan Han, Ph.D.Emory University, Atlanta, GAEnhanced anti-tumor immunity by regulation of IgG sialylation

David L. Lampi Hermanson, Ph.D.*University of Minnesota, Minneapolis, MNChimeric antigen receptor directed NK cellular immunotherapy

Lingfeng Liu, Ph.D.University of California, San Francisco, San Francisco, CAOptimizing T cells for cancer therapy: A synthetic biology approach

Yvonne K. Mburu, Ph.D.Institut Curie, Paris, FranceMucosal-associated invariant T (MAIT) cells in anti-tumor therapyLloyd J. Old Memorial Fellow

Kristen E. Pauken, Ph.D.*Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PAAnti-PD-1 immunotherapy: Mechanisms and impact on sustainability of CD8+ T cell responsesRobertson Foundation Fellow

Helene M. Salmon, Ph.D.*Icahn School of Medicine at Mount Sinai, New York, NYContribution of the cutaneous myeloid network to melanoma response to therapyRobertson Foundation Fellow

Xiaolei Su, Ph.D.University of California, San Francisco, San Francisco, CAMechanisms underlying the dynamic organization of T cell microclustersEugene V. Weissman Fellow

Adam Williamson, Ph.D.*University of California, San Francisco, San Francisco, CAActivation of corpse engulfment to alleviate tumor-induced neurotoxicity

Signaling and Cell Communication

John S. Burg, Ph.D.Stanford University School of Medicine, Stanford, CAStructural studies of Wnt receptor activation

Anne Marie Christine Chauveau, Ph.DMemorial Sloan Kettering Cancer Center, New York, NYRole of DGKα in cytoskeleton remodeling and T cell effector functions

Adam H. Courtney, Ph.D.*University of California, San Francisco, San Francisco, CAElucidation of Lck feedback mechanismsRobertson Foundation Fellow

Maria P. Frushicheva, Ph.D.*Massachusetts Institute of Technology, Cambridge, MAZAP-70 and Syk regulation in B cell chronic lymphocytic leukemia

Jeffrey E. Grotzke, Ph.D.Yale School of Medicine, New Haven, CT Membrane receptors and associated signaling pathways in cross presentation

Bengt Martin Gustavsson, Ph.D.*University of California, San Diego, La Jolla, CAStructural basis of CXCR7 ligand binding and signalingRobertson Foundation Fellow

Vincent Christopher Luca, Ph.D.Stanford University School of Medicine, Stanford, CADeconstructing the structural mechanisms of cytokine-mediated JAK activation

Boryana N. Manz, Ph.D.University of California, San Francisco, San Francisco, CANegative regulation of SFK and Ras by Dok1

Giulia Pasqual, Ph.D.Whitehead Institute for Biomedical Research, Cambridge, MAIn vivo tracking of B cell-T cell interactions in the germinal center

Debrup Sengupta, Ph.D.Yale School of Medicine, New Haven, CT Membrane trafficking events regulating cross presentation

Vanja Sisirak, Ph.D.Columbia University Medical Center, New York, NYNovel regulator of DNA recognition by dendritic cells

Sergio A. Quezada, Ph.D.University College London Cancer Institute, London, United KingdomMechanisms underpinning the function of regulatory and effector tumor-reactive CD4+ T cells during tumorigenesis and cancer immunotherapy

Peter A. Savage, Ph.D.University of Chicago, Chicago, ILEndogenous CD4+ regulatory T cell and CD8+ T cell responses in a mouse model of autochthonous prostate cancer

Joseph C. Sun, Ph.D.Memorial Sloan Kettering Cancer Center, New York, NYNatural killer cell responses against cancer and infectious disease

Ryan M. Teague, Ph.D.Saint Louis University School of Medicine, St. Louis, MOOvercoming obstacles for improved adoptive T cell immunotherapy

Liang Zhou, M.D., Ph.D.Northwestern University, Evanston, ILMolecular mechanisms of action of Ahr in T cell differentiation and function

Sergio A. Quezada, Ph.D., CRI investigator at the University College London Cancer Institute

CRI postdoctoral fellows Georg A.J. Gasteiger, M.D., and Jesse Green, Ph.D., wiith CLIP investigator Alexander Y. Rudensky, Ph.D., at Memorial Sloan Kettering Cancer Center

Ellen Puré, Ph.D.University of Pennsylvania School of Veterinary Medicine, Philadelphia, PAAdoptive T cell therapy targeted to tumor stroma to treat lung cancerGenentech Investigator

Jeffrey C. Rathmell, Ph.D.Duke University Medical Center, Durham, NCMetabolic immunosuppression of T cells in clear cell renal cell carcinoma and anti-PD-1 therapyWade F.B. Thompson Investigator

Jeffrey V. Ravetch, M.D., Ph.D.The Rockefeller University, New York, NYEnhancing the immunotherapeutic activity of anti-CD40 antibodies

Alexander Y. Rudensky, Ph.D.*Memorial Sloan Kettering Cancer Center, New York, NYImmunoregulatory correlates of a phase I/II study of mogamulizumab in subjects with advanced and/or metastatic solid tumorsGenentech Investigator

Bruno Sainz Jr., Ph.D.*Universidad Autónoma de Madrid, Madrid, SpainRole of the innate immune system in promoting cancer stem cells

Robert D. Schreiber, Ph.D.Washington University School of Medicine, St. Louis, MOA genomics-based approach to facilitate checkpoint blockade cancer immunotherapy

Mark J. Smyth, Ph.D.*QIMR Berghofer Medical Research Institute, Queensland, AustraliaThe preclinical validation of CD96 as a checkpoint target for cancer immunotherapy

Ryan M. Teague, Ph.D.*Saint Louis University School of Medicine, St. Louis, MODefining the mechanisms of human T cell rescue by checkpoint blockade immunotherapy Coordinated Cancer InitiativesFunding for research in specified cancer areas deemed able to provide clinically relevant insights and discoveries with the potential to accelerate development of cancer immunotherapies.

Maha Ayyoub, Ph.D., and Danila Valmori, Ph.D. Centre de Lutte Contre Le Cancer Nantes-Atlantique, Nantes, FranceVaccination strategies for the treatment of epithelial ovarian cancer; Placenta-cancer antigens as potential targets for immunotherapy of epithelial ovarian cancer

Hearn Jay Cho, M.D., Ph.D.Icahn School of Medicine at Mount Sinai, New York, NYVaccine immunotherapy program in multiple myeloma

Pramod K. Srivastava, M.D., Ph.D.University of Connecticut School of Medicine, Farmington, CTGenomics-driven identification of true tumor-specific antigens and their use in immunotherapy of spontaneous prostate cancers

Clinical Accelerator TrialsThe Clinical Accelerator brings together the best capabilities of the world’s leading academic researchers, drug companies, and a unique nonprofit venture fund to kick-start the development of powerful new treatments for cancer patients. To view a list of all current sites and lead investigators, go to page 50.

Funded Studies

A first-in-human single ascending dose study of TRX518 in subjects with unresectable stage III or stage IV malignant melanoma or other solid tumor malignancies• Henry Koon, M.D., University

Hospitals, Cleveland, OH• Dale Shepard, M.D., Ph.D.,

Cleveland Clinic, Cleveland, OH• Jedd D. Wolchok, M.D., Ph.D., and

Margaret Callahan, M.D., Ph.D., Memorial Sloan Kettering Cancer Center, New York, NY

A phase I study of NY-ESO-1 vaccine in combination with ipilimumab in patients with unresectable or metastatic melanoma, for whom treatment with ipilimumab is indicated• Jonathan S. Cebon, Ph.D., FRACP,

Austin Health/Ludwig Cancer Research, Melbourne, Australia

• Craig E. Devoe, M.D., North Shore LIJ, North Shore University Hospital, Manhasset, NY

• Philip Friedlander, M.D., Icahn School of Medicine at Mount Sinai, New York, NY

• Michael A. Postow, M.D., Memorial Sloan Kettering Cancer Center, New York, NY

• Craig L. Slingluff Jr., M.D., University of Virginia Cancer Center, Charlottesville, VA

• Hussein Tawbi, M.D., Ph.D., University of Pittsburgh Cancer Institute, Pittsburgh, PA

A phase I study to evaluate the safety and tolerability of anti-PD-L1, MEDI4736, in combination with tremelimumab in subjects with advanced solid tumors• Kunle Odunsi, M.D., Ph.D., Anna-

Maria Kellen Clinical Investigator, Roswell Park Cancer Institute, Buffalo, NY

• Patrick Ott, M.D., Ph.D., Dana-Farber Cancer Institute, Boston, MA

• Jedd D. Wolchok, M.D., Ph.D., and Margaret Callahan, M.D., Ph.D., Memorial Sloan Kettering Cancer Center, New York, NY

Rakesh K. Jain, Ph.D.*Massachusetts General Hospital, Boston, MAImproving immunotherapy for metastatic breast cancer via normalization of the tumor microenvironment

Susan M. Kaech, Ph.D.*Yale School of Medicine, New Haven, CTEnhancing immunotherapy-based cancer treatments through CD40-dependent immunomodulation of the tumor microenvironmentWade F.B. Thompson Investigator

W. Martin Kast, Ph.D.University of Southern California, Los Angeles, CAAnti-CTLA-4 immune modulation following chemoradiation in cervical cancer patients

Paul Klenerman, M.D., Ph.D.*University of Oxford, Oxford, United KingdomLicensing human MAIT cells to kill hepatocellular carcinomas

Ming O. Li, Ph.D.Memorial Sloan Kettering Cancer Center, New York, NYThe Adrb-cAMP-ICER pathway in control of mammary tumor immune evasion

Roger S. Lo, M.D., Ph.D.*UCLA Medical Center, Los Angeles, CADeterminants of responses to anti-PD-1/PD-L1 therapy and its combination with BRAF/MEK co-targeting in melanomaWade F.B. Thompson Investigator

Hiroyoshi Nishikawa, M.D., Ph.D.Osaka University, Osaka, JapanNovel cancer immunotherapy targeting regulatory T cells by anti-CCR4 monoclonal antibodies

Jonathan S. Cebon, Ph.D., FRACPAustin Health/Ludwig Cancer Research, Melbourne, AustraliaEvaluation of ROPN and SPANX as targets for antigen-specific immunotherapyWade F.B. Thompson Investigator

Dean W. Felsher, M.D., Ph.D.*Stanford University School of Medicine, Stanford, CAOncogene addiction and immune activation

Ian Hector Frazer, M.D., FRCPAUniversity of Queensland, Queensland, AustraliaOptimizing immunotherapy for squamous cancer

Thomas F. Gajewski, M.D., Ph.D.University of Chicago, Chicago, ILIdentification of tumor-intrinsic signaling pathways that inhibit host immune responses as potential therapeutic targets to expand the applicability of immunotherapyOliver R. Grace Investigator

Michael Goldberg, Ph.D.*Dana-Farber Cancer Institute, Boston, MAUse of CRISPR/Cas9 platform to improve function of cytotoxic T lymphocytes against melanoma

Clinic and Laboratory Integration Program (CLIP)Two-year grants that provide catalytic support for translational laboratory studies designed to answer new scientific questions that arise in the clinic, with special focus on improving immunotherapy for cancer patients.

Gosse J. Adema, Ph.D.Radboud University Medical Centre, Nijmegen, The NetherlandsExploiting in situ tumor destruction techniques for the in vivo modulation of anti-tumor immunity

Matteo Bellone, M.D.*Fondazione Centro San Raffaele, Milan, ItalyCombining adoptive T cell therapy to tumor vessel targeting and checkpoint blockade for cancer therapy

Nina Bhardwaj, M.D., Ph.D.Icahn School of Medicine at Mount Sinai, New York, NYMMP-2 promotes melanoma progression through Toll-like receptor mediated mechanismsWade F.B. Thompson Investigator

Bruce R. Blazar, Ph.D.*University of Minnesota, Minneapolis, MNLymphoid organ repair after cancer therapy for improving anti-tumor immune responses

A phase II study to evaluate the clinical efficacy and safety of standards of care in combination with checkpoint blockade in patients with glioblastoma*• David Reardon, M.D., Dana-Farber

Cancer Institute, Boston, MA

Phase I/II study of chemo-immunotherapy with Toll-like receptor 8 agonist VTX-2337 and checkpoint blockade in subjects with recurrent, platinum-resistant ovarian cancer for whom pegylated liposomal doxorubicin (PLD) is indicated*• George Coukos, M.D., Ph.D.,

University Hospital of Lausanne, Lausanne, Switzerland

Nina Bhardwaj, M.D, Ph.D., CLIP investigator, with postdoctoral fellows at the Icahn School of Medicine at Mount Sinai

Antoni Ribas, M.D, Ph.D., CVC Trials Network member, with investigator at UCLA Medical Center


Trials Supported with Reagents

A multi-peptide vaccine plus Toll-like receptor agonists in melanoma patients, with evaluation of the injection site microenvironment for resected stage IIB-IV*• Craig L. Slingluff Jr., M.D.,

University of Virginia Cancer Center, Charlottesville, VA

A phase I open label, multicenter, multi-ascending dose trial evaluating the safety, tolerability, and immunogenicity of intramuscular recombinant NY-ESO-1 protein with GLA-SE adjuvant in patients with unresectable or metastatic cancer expressing NY-ESO-1 cancer• Immune Design, Seattle, WA

A phase I study of cancer vaccine CHP-NY-ESO-1 in combination with Poly-ICLC in patients with esophageal cancer or malignant melanoma expressing NY-ESO-1• Hiroshi Shiku, M.D., and Shinichi

Kageyama, M.D., Mie University School of Medicine, Mie, Japan

A phase I study of concomitant WT1 analog peptide and NY-ESO-1*• David O’Malley, M.D., The Ohio

State University Wexner Medical Center, Columbus, OH

• Paul Sabbatini, M.D., Memorial Sloan Kettering Cancer Center, New York, NY

A phase I study of vaccination with NY-ESO-1 protein mixed with Poly-ICLC, OK-432 (Picibanil®), and ISA-51 (Montanide®) in patients with advanced cancers expressing NY-ESO-1 antigen• Yuichiro Doki, Ph.D., and Hisashi

Wada, M.D., Ph.D., Osaka University, Osaka, Japan

A phase IA/IB study of vaccination with NY-ESO-1 protein, Poly-ICLC, and mogamulizumab in patients with adult T cell leukemia/lymphoma expressing NY-ESO-1 antigen• Yuzuru Kanakura, Ph.D., and

Hiroyoshi Nishikawa, M.D., Ph.D., Osaka University, Osaka, Japan

A pilot study of a novel multimodality immuno-chemotherapy platform for patients with advanced cutaneous T cell lymphoma• Catherine M. Diefenbach, M.D.,

NYU Langone Medical Center, New York, NY

A pilot study of the immunogenicity of a 9-peptide breast cancer vaccine plus Poly-ICLC in stage IB-IIIA breast cancer• Patrick M. Dillon, M.D., University

of Virginia Cancer Center, Charlottesville, VA

Evaluation of safety and immunogenicity of a multi-phosphapeptide vaccine plus Poly-ICLC in participants with melanoma • Victor H. Engelhard, Ph.D., and

Craig L. Slingluff Jr., M.D., University of Virginia Cancer Center, Charlottesville, VA

Phase I study of NY-ESO-1 protein + Poly-ICLC +/- Montanide® ISA-51 VG vaccine in patients with advanced malignant melanoma• Nina Bhardwaj, M.D., Ph.D., Icahn

School of Medicine at Mount Sinai, New York, NY

Phase I/II trial of a long peptide vaccine (LPV8) + TLR agonists for resected stage IIB-IV (Mel60)*• Craig L. Slingluff Jr., M.D.,

University of Virginia Cancer Center, Charlottesville, VA

Safety and immunogenicity of vaccination with XAGE1b long peptides combined with Poly-ICLC in patients with stage III/IV pulmonary adenocarcinoma• Christian Taube, M.D., and

Maarten L. Zandvliet, Ph.D., Leiden University Medical Center, Leiden, The Netherlands

Correlative and Laboratory Studies

Development of cancer immunotherapy targeting regulatory T cells• Hiroyoshi Nishikawa, M.D., Ph.D.,

Osaka University, Osaka, Japan

Early-phase NY-ESO-1 clinical trials in patients with epithelial ovarian, fallopian tube, or primary peritoneal carcinoma and monitoring of tumor-specific immune responses• Maha Ayyoub, Ph.D., and Danila

Valmori, Ph.D., Centre de Lutte Contre Le Cancer Nantes-Atlantique, Nantes, France

Immunological monitoring for the CVC trials• Sacha Gnjatic, Ph.D., Icahn School

of Medicine at Mount Sinai, New York, NY

NY-ESO-1 and mixed bacterial vaccine clinical trials and immune monitoring• Elke Jäger, M.D., Krankenhaus

Nordwest, Frankfurt, Germany

Phase II study of CTLA-4 blockade and low dose cyclophosphamide in patients with advanced malignant melanoma after failure of at least one prior therapy• Nina Bhardwaj, M.D., Ph.D., Icahn

School of Medicine at Mount Sinai, New York, NY

• Anna C. Pavlick, D.O., NYU Langone Medical Center, New York, NY

Preclinical toxicity studies to enable the clinical development of the XAGE1b peptide vaccine• Cornelis J.M. Melief, M.D., Ph.D.,

Leiden University Medical Center, Leiden, The Netherlands

Vaccination of melanoma patients (stage II-IV) with ImmuFact IMP321, tumor antigenic peptides, and Montanide• Daniel E. Speiser, M.D., University

Hospital of Lausanne, Lausanne, Switzerland

Reagent Manufacture

Production of NY-ESO-1 overlapping peptides for use in a variety of trials• PolyPeptide Laboratories San

Diego, San Diego, CA

Poly-ICLC stability testing• Oncovir, Inc., Washington, DC

Leveraged GrantsSpecial partnerships to explore novel preclinical and clinical studies in high-priority research areas.

Cancer Immunology Translational Research Dream TeamJames P. Allison, Ph.D., The University of Texas MD Anderson Cancer Center, Houston, TX, and Antoni Ribas, M.D., Ph.D., UCLA Medical Center, Los Angeles, CAImmunologic checkpoint blockade and adoptive T cell transfer in cancer therapyIn partnership with the Entertainment Industry Foundation/Stand Up To Cancer

Carl H. June, M.D., and Gregory L. Beatty, M.D., Ph.D.Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA Mesothelin-specific chimeric antigen receptor (CAR) T cell therapy for pancreatic cancerIn partnership with the Lustgarten Foundation

Designated GrantsGrants to support research projects and public education and awareness initiatives for which, in most cases, donors have specifically raised funds.

George Klein, M.D., D.Sc.*Karolinska Institute, Stockholm, SwedenStudies on Epstein-Barr virus, oncogenes and tumor suppressor genes, tumor immunology, and inhibition of tumor cell growth by stroma cellsIn partnership with the Concern Foundation

Malcolm A.S. Moore, D.Phil.*Memorial Sloan Kettering Cancer Center, New York, NY The study of hematopoietic stem cells and progenitor populations in normal and cancer cellsGar Reichman Laboratory

ZERO-The End of Prostate Cancer, Washington, DC*Support for the Drive Against Prostate Cancer mobile screening vehicle

Annual AwardsIn addition to providing financial support to researchers and investigators, CRI also honors scientists and community leaders with achievement awards.

William B. Coley Award for Distinguished Research in Basic and Tumor ImmunologyAnnual prize given to one or more scientists whose discoveries in the fields of immunology or tumor immunology contribute to the advancement of immune system-based therapies for cancer.Michael B. Karin, Ph.D.*University of California, San Diego

Lloyd J. Old Award in Cancer ImmunologyAward recognizes an active scientist whose outstanding and innovative research in cancer immunology has had a far-reaching impact on the cancer field.Robert D. Schreiber, Ph.D.*Washington University School of MedicineIn partnership with the American Association for Cancer Research

Frederick W. Alt Award for New Discoveries in ImmunologyPrize honoring a former postdoctoral fellow in recognition of outstanding success in academia or industry for research that may have a potentially major impact on immunology.Jill O’Donnell-Tormey, Ph.D.*Cancer Research Institute

Oliver R. Grace Award for Distinguished Service in Advancing Cancer ResearchAnnual prize that recognizes the contributions of dedicated laypersons whose leadership has had a significant impact on cancer research.Bahija Jallal, Ph.D.*AstraZeneca/MedImmuneSean Parker*Serial Tech Entrepreneur and Philanthropist


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None of the lifesaving research that CRI supports would be possible without the generous financial

contributions of our donors—individuals, foundations, and corporations. CRI honors those donors by being responsible and strategic about its resources, giving our supporters confidence that we will use their money wisely to achieve the greatest impact possible.

From the thousands of individuals who make one-time donations, to the many families who give yearly in memory of a loved one, to our trustees who give generously of both their time and money, no gift to CRI goes unappreciated. These contributions continue to make a difference in the life of the organization.

Among the many notable fundraising events of this past year were the 27th Annual Awards Dinner, which raised a record-breaking $1.5 million, and the 2014 Through the Kitchen benefit, which raised $1.2 million for CRI’s postdoctoral fellowship program. Together, unrestricted donor contributions to CRI totaled $24.5 million in the last year.

HONORING OUR

DONORSWhen I went through all the charities, I felt that CRI was doing what I wanted done, where the majority of the money was spent on research.Penny Bolton, Bras for a Cause

“

01 Lauren Veronis (right) and guests, Through the Kitchen02 Will and Wandy Hoh, Through the Kitchen03 Michael Kellen, Adam Kolom, and Charles J. Hecht04 CRI trustee and golf event chair Carlos Ferrer (center) and guests05 Joel Paula, Scott Snyder, and friend

06 Peter Coley, ING New York City Marathon07 Young Philanthropists Council Winter Soiree attendees08 Young Philanthropists Council Winter Soiree attendees09 Bras for a Cause community fundraisers


$1,000,000+Bristol-Myers Squibb Georgia and Don GogelAnna-Maria and Stephen Kellen FoundationMedImmune, Inc.Sean N. Parker FoundationRobertson FoundationVentiRx Pharmaceuticals, Inc.

$500K - $999KCure Brain Cancer FoundationMr. and Mrs. John EckersonJohn and Jean Eckerson Family FoundationMr. and Mrs. Sean P. FaheyShelter Hill FoundationBetsy and Paul Shiverick

$100K - $499KConcern FoundationEstate of Salvatore CorsaroMr. and Mrs. Maurice J. CunniffeLeslie and Bob DahlThe Robert I. Fendrich Family TrustGenentech, Inc.Mr. and Mrs. Oliver R. Grace Jr.F.M. Kirby Foundation, Inc.Estate of Francis R. LindenHarvey A. Linden Charitable Remainder TrustThe Ambrose Monell FoundationEstate of Carmen F. PattiMr. and Mrs. Brian RianoSean I. SaulerEstate of George C. Thomas Jr.The Wildflower Foundation

$50K - $99KMr. and Mrs. Edgar R. BernerEstate of Frederick J. BrandBristol-Myers Squibb Foundation, Inc.Jennifer L. Brorsen and Richard M. DeMartiniMr. and Mrs. Russell L. Carson

The John and Christine Fitzgibbons FoundationMr. and Mrs. Victor F. GanziOliver R. Grace Charitable FoundationMarion Esser Kaufmann FoundationMr. and Mrs. Alexander P. LynchThe Honorable Colleen McMahon and Frank V. SicaAndy and Tom MendellOrinoco FoundationMr. and Mrs. Andrew M. PaulThe Linda C. Pinkus FundDavid M. Polen Retirement Plan Proceeds TrustLief D. RosenblattJeanne and Herb SiegelJane and James SternSharzad and Michael TargoffDiane and Tom TuftUeberroth Family Foundation

$10K - $49KAgenusAllen & Company, Inc.California Fund of the Hugh J. Andersen FoundationDr. Eva Andersson-Dubin and Mr. Glenn DubinAstellas Pharma US, Inc.Rose M. Badgeley Residuary Charitable TrustEstate of Ella R. BanksThe Jeanne E. and Jacob A. Barkey Memorial FundJeri BerryhillThe Blavatnik Family FoundationBloombergThe Boisi Family FoundationBonbright Family Foundation TrustThe BurtonsChalkstream Capital Group, LPMr. and Mrs. Alex Clain-StefanelliClayton, Dubilier & Rice, LLCAnn and Geoffrey O. ColeyFrederic R. Coudert Foundation

Karen and Matthew CrewsDancing Tides Foundation Inc.Debevoise & Plimpton LLPDendreonMr. and Mrs. Glenn J. DeSimoneMr. and Mrs. Brennan DiazThea Duell and Peter CookPatrick J. DurkinAlbert Nathan Eisenberg Charitable Foundation TrustAlixandra G. EnglundEstron Chemical, Inc.Mr. and Mrs. Carlos A. FerrerFinneran Family FoundationMr. and Mrs. Norman FreedmanSamuel Freeman Charitable TrustRobert C. GalvinSophie GarafolaEstate of Carole GardnerMr. and Mrs. Peter A. GeorgescuGoldman, Sachs & Co.Herman B. Golub Charitable TrustJohn G. & Jean R. Gosnell Foundation, Inc.Mrs. Oliver R. GraceGreen Charitable Foundation, Inc.Joyce Green Family FoundationMary GursterHagedorn FundShirley & Burt Harris Family FoundationMargaret Hayman TrustMr. and Mrs. Philip HemplemanThe Hertz CorporationMarlene Hess and James ZirinGrace Humphrey Testamentary TrustThe Hurlbert Family FoundationHelen L. Kay Charitable TrustJames KellyMr. and Mrs. Kenneth G. LangoneJo Carole and Ronald S. LauderThe Florence & Edgar Leslie Charitable TrustMacHeist.comMeyer Marcus Revocable TrustEdward N. & Margaret G. Marsh Foundation

McCann Charitable FoundationMerckMorgan Stanley Smith Barney LLCMr. and Mrs. Jacques C. NordemanThe Kenneth T. and Eileen L. Norris FoundationPaul and Anna Oschwald TrustPerri Peltz and Eric RuttenbergPeregrine Pharmaceuticals, Inc.Polo Ralph Lauren FoundationRed Crane FoundationMary RicksJulian RobertsonMr. and Mrs. Steven RothThe Mortimer D. Sackler Foundation, Inc.Lily SafraAdolph and Ruth Schnurmacher FoundationEdith M. Schweckendieck TrustsPaul J. SekhriSillaJenThe Speedwell FoundationWalter & Louise Sutcliffe FoundationMr. and Mrs. Alfred TaubmanMr. and Mrs. Andrew K. TsaiEstate of Zelda M. UtheVarian Medical Systems FoundationLuc VautmansLauren and John VeronisVMware FoundationMr. and Mrs. Ronald G. WeinerEstate of Elizabeth A. WeiserWhiting FoundationSteve Wiggins

$5K - $9KAnonymous (4)AbbVie Inc.Affimed Therapeutics AGJames P. Allison, Ph.D.Amscan Inc.Mr. and Mrs. John BaderPhyllis & Stewart Bain Family FundRobert W. Baird & Co.

The Cancer Research Institute’s ability to advance important science and facilitate the development of immunotherapies is made possible through the generous support of our donors. Acknowledgements listed here reflect contributions made to CRI between July 1, 2013, and June 30, 2014.

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SC.R. Bard, Inc.Freda Wilkerson BassJoanne BenedictCurtis BerganBiovest InternationalMr. and Mrs. James C. BlairArnold Bortman Family FoundationMr. and Mrs. Daniel BrodskyMr. and Mrs. Charles BronfmanCelldex TherapeuticsMr. and Mrs. John ChadwickJoseph M. CohenCorning IncorporatedKimberly CoronadoCrane Foundation, Inc.Danem FoundationFootprints for PeaceConnie Frank FoundationFrontier CommunicationsRoger and Brenda Gibson Family FoundationMr. and Mrs. Jay GoldbergEstate of Victor E. HansenJ. Ira and Nicki Harris Family FoundationNoreen and Fred HassanGertrude L. Hirsch Charitable TrustRochelle and David A. Hirsch Foundation, Inc.Estate of Nurine HokeInnovate International Intelligence & Integration, LLCMr. and Mrs. George KaufmanDonald L. KingJoel KleinHeidi and Michael KlugerRachel Rutherford Englund KnappMr. and Mrs. David H. KochSteven KroftThe Ralph & Ricky Lauren Family Foundation, Inc.Lazard Freres & Co. LLCDalia and Larry LeedsMorris and Lillie Leibowitz Charitable TrustJeremy M. LevinThe Lind PartnersMr. and Mrs. John LykouretzosMr. and Mrs. D. Scott MackesyLeslie and Thomas MaherasMailers Haven LLCEvan McDonald-Stewart

McMullan Family FundMedical & Biological Laboratories Co., Ltd.National Association of Buffalo Soldiers and Troopers Motorcycle ClubSebastian V. NicastroParkell, Inc.PDT, Inc.Jane and Robert PerkinsonVickie and Rahn PitzerPortfolio Advisors, LLCVerne C. PowellMr. and Mrs. Paul E. RaetherJames A. RandelAdam J. Richter Charitable TrustThe Edward John and Patricia Rosenwald FoundationKevin W. SharerMichael Charles SharpEric P. Sheinberg FoundationMr. and Mrs. Ernest B. SmithSue Anne SmithSpredfastMr. and Mrs. Leonard N. SternThe Laurence Cecil and Fay Strout Revocable TrustMr. and Mrs. Miles M. StuchinTESARO, Inc.ThomasARTSThe Yaspan Unterberg FoundationVestar Capital PartnersMr. and Mrs. Jacob VosWeatherspoon Charitable Foundation

$1,000 - $4,999Anonymous (25)AeroDyn Wind TunnelBill AlbanoPatrick AllareJane B. AllenAllison, Inc.Alpha Delta KappaAmerican Express FoundationDonald W. AmmermanMr. and Mrs. Dale P. AndersonRobert G. AndrewsAngelo, Gordon & Co.Apple Inc.Argos Therapeutics, Inc.Sandra T. ArnettAtlas Energy Holdings Operating Co., LLC

27th Annual Awards Dinner, Cipriani 42nd Street

Ann M. BaileyBakercorpCharles BanksMary R. Baque TrustWilliam D. BarboMr. and Mrs. Padrick BarrettThe Barrington Foundation, Inc.Pamela S. Barry, Ph.D., and Thomas W. Schneider, Ph.D.Jane M. BartelsMr. and Mrs. Gerald BartolomucciBasintek, LLCMr. and Mrs. Charlie Baynes-ReidThe Sally Beatty and Robert Sawyer Charitable FoundationRobbie and Ted BeatyMr. and Mrs. Everett A. BellSusan W. BentonMr. and Mrs. Jonathon BerezinskiJeffrey BerkawThe Berkowitz Family FoundationBerkshire FundMr. and Mrs. Edward M. BermasMr. and Mrs. Philip BerneyMark BerryMr. and Mrs. Larry D. BillenBloom FarmsBMR Construction Management, Inc.Bogatin Family FoundationMr. and Mrs. Jeffrey D. BoltonMarisa BoltonMr. and Mrs. Oren BramsonCharlotte BrennerNancy Brinker Charitable FoundationAmy Bronstein

The Bryn Mawr Trust CompanyTory BurchMr. and Mrs. Tom BurmanRobert B. BurnettSuzanne E. BurnetteCharles C. ButtC4 SportsThe Campbell FamilyMr. and Mrs. Rohn CampbellMr. and Mrs. Arthur L. CarterPamela and John CasaudoumecqCastle Harlan, Inc.The Cayuga FoundationDr. Jacob M. ChackoLewis CheneyMr. and Mrs. Daniel K. ClarkSteve CohenSteven B. ColemanJack ComerMr. and Mrs. Richard CoreyCorporate Risk SolutionsMr. and Mrs. Ronald CoutureMr. and Mrs. James R. CoyleDuffy CredleSusan and William CrewsKirk CromerRobert CroninJohn CrookNancy and Keith CroxtonCureVac GmbHMr. and Mrs. John R. Curtis Jr.CVS CaremarkMr. and Mrs. Barrie M. DamsonJohn DanhaklDave’s Gourmet, Inc.

Fred DavisSavannah de SavaryDella Calce Private Foundation, Inc.Mr. and Mrs. Rutger deQuayHéléne Déramond and Ted Totman Mr. and Mrs. John H. DobbinsJohn Patrick DriscollDTIS LLCJames DunneNancy P. DurrKurt DustinAngela and Christian EhemannEisnerAmper LLPEric EllenbogenSteven K. EllisEmarzium LLCEnergyIQHelen B. Esokait TrustE. Joseph Evans Charitable TrustDr. and Mrs. Anthony B. EvninBenjamin FalchukMr. and Mrs. Thomas E. FalgoutThe Milton and Sylvia Feldman FoundationMr. and Mrs. Mitchell B. FeldmanLouise Egdorf FescineThe Fisher Family Charitable FundKristen Kelly FisherEric M. FlomJohn A. FloodJosh FordForesters Executive Leadership TeamMr. and Mrs. Thomas FrancoLucy FreundJacquelyn and Stuart FriedlandGalena BiopharmaNeil GallagherMr. and Mrs. Paul GalvinSarah Belk GambrellTimothy GarryLinda GaseLinda and Daniel GerdingMr. and Mrs. Daniel GerstMr. and Mrs. Jeffrey R. GibbonsCharles GibsonRichards GilbertGirlfriends Films, Inc.Mr. and Mrs. David GlendinningMr. and Mrs. Kenneth H. GlobusLaurie and Jeffrey GoldbergerEllen M. Golub Charitable FoundationGoogle, Inc.

Lee GordonAnthony GranadoWalter GrandfieldMr. and Mrs. Jeffrey Adam GreenJon Adam GreenGreen Mountain Coffee Roasters, Inc.Alexis Gregory FoundationMr. and Mrs. Peter GregoryMr. and Mrs. William M. GutowitzMr. and Mrs. Bruce J. HaberRussell HackmannIsabelle HamiltonMr. and Mrs. Lee HangerFleur and Leonard HarlanThe Harris Family Charitable FundKaren HarrisMr. and Mrs. Steven K. HarrisMr. and Mrs. William B. HarrisonDr. William A. HaseltineMarc HassanPaul HayauxHead Family TrustDonald B. Hebb Jr.HED, Inc.Renee HerzingBeth HickeyMr. and Mrs. James P. HigginsMark HimelsteinDeborah A. HodesMr. and Mrs. Paul HoehneMr. and Mrs. Burt HoffmanMr. and Mrs. William HohBruce R. HuebnerHZDG Development DepartmentCapt. Scott IngrahamKajeen G. IrwinDeborah and Arthur JacobsonMr. and Mrs. Robert J. Jacobson Jr.Mr. and Mrs. Jeff JaenickePurvi JanardhanRobert W. JenkinsAnne and Johnny JonesJudith JonesMatt JonesKane Environmental Engineering, Inc.Karuna FoundationKate’s CureLisa KellerMr. and Mrs. Michael J. Kenig Jr.Mr. and Mrs. Richard KernsMichael F. KleinMarilyn and Robert Klett

Marjorie A. KnievelRichard C. KowalskiWilliam KremerAmy and Ernie KremlingLee KuntzPerry A. KupietzMr. and Mrs. David P. KuselLa Miet ClubJohn and Sheila LakeMr. and Mrs. Benjamin V. LambertKonstantina LampioneDr. and Mrs. Richard LandesmanLandmark Credit UnionCarey F. LathropJeffrey T. LeedsMr. and Mrs. Richard S. LeFrakNina LesavoyAndrei LevinCharles and Margaret Levin Family FoundationMichael S. LewinCaroline LoebCarol and Gary LucidoMr. and Mrs. Pete and Jeanine LunardiMr. and Mrs. Donald LundholmMr. and Mrs. Michael D. MagidsonLaurence and Tony MagroChris & Melody Malachowsky Family FoundationMr. and Mrs. Jay MandelbaumMr. and Mrs. Michael MarantoJohn MarinoJeanne A. Markey and Gary L. AzorskyJane Martin and Stuart KatzMr. and Mrs. Redge A. MartinMartins Construction CorporationDr. Philip MastmanRobert MauerNancy L. MauroKammy J. MaxfeldtMr. and Mrs. David MaymanLynn G. McAteeKate A. McKayRobert M. McKeonMichael McNicholasNelson Mead FundRichard Meier FoundationMr. and Mrs. Dennis MejillonesMr. and Mrs. Martin MelsonThe Sue and Eugene Mercy Jr. Foundation Inc.Microsoft

Charles MillenderSteven MislockDr. Stephen MonroeMontgomery County 4-H Beef ClubDana MoranMarya M. MoskowitzJason MuchMr. and Mrs. Jeremy W. MullendoreMurfreesboro Medical Clinic, PANusrat NabiMiles NadalJenks Necker Charitable FundSergei A. Nedospasov, Ph.D., D.Sc.New York Life Insurance CompanyKevin K. NickelMr. and Mrs. Robert B. NolanStephanie and Peter Nolan FoundationNorth Carroll High SchoolNortheast Union Group Inc.Jeffrey NuechterleinMr. and Mrs. Jeffrey NusbaumWinifred K. NyceMr. and Mrs. Gregory A. OdleChristine OgataRoyce E. Oliver Jr.James A. OlsonOnce for All TrustMr. and Mrs. John OrlandoOttilie FundDarryl L. ParrishPartners Capital Investment Group, LLCMr. and Mrs. Kevin PaynePear Valley Vineyard, Inc.Mr. and Mrs. Jeffrey M. PeekMichael PenaDenise M. PetersonHolly Peterson FoundationRobert L. PetersonMr. and Mrs. Theodore PeytonKevin PfauMr. and Mrs. Regis PhilbinAngela PhillipsMr. and Mrs. Richard PleplerJennifer and Bruce PolnickyMr. and Mrs. Robert A. PosnerAndrea and Andrew PotashBeth A. PotterMr. and Mrs. Robertus PrajogiJulie and Paul PrestopnikQMT Associates, Inc.Qualcomm

Brenna Quinn and Sean O’HaraRenate and Walter RadosGrace RapinchukSanjay RattanFred ReedeHulda and Michael RefermatMr. and Mrs. Jonas J. RieterMr. and Mrs. David RiparbelliFrank E. RobertsDave Robertson Memorial FundMax J. RohaMr. and Mrs. Jeffrey RosenbluthRosetta Resources, Inc.Rosson Phillips GroupRotary Club of Queensburgh, Durban, South AfricaMr. and Mrs. Jonathan RothEdward RoweBarry D. RoyRobert RushtonThe Rust Family FoundationJohn SalisburySuzanne SalmMichael ScallanMrs. Susan P.N. Schaller and Mr. Richard G. Schaller William O. SchmaleDavid N. SchrierSchulman Family FoundationHenry C. Schulte and Virgina M. Schulte FoundationSeaman Family FoundationCharles D. SearsUsha SethMr. and Mrs. William B. ShawMr. and Mrs. John SheehanRocky R. ShererMr. and Mrs. Stephen C. SherrillShowin’ for a CureAaron ShumakerPeggy SiegalMr. and Mrs. Brian D. SilvermanSteven SimonLinda G. SingerLois V. SmigelBetty S. SmithCynthia SmithMr. and Mrs. Jeffrey Q. SmithMary F. Smith Family FoundationRuthanne SmithMaksim SmotritskiyLisa S. Snoddy

Solarbos Inc.Sotheby’sJessica SprietSt. Thomas Aquinas High School BaseballRobin StamerStamford HospitalBonnie M. and Robert J. StapletonThe Honorable and Mrs. Kenneth W. StarrState Metal Industries, Inc.Mary K. Steffens FoundationThe Sternlicht Family Foundation Inc.Patricia StohlerRaul J. SuarezEstate of Myrtle B. SummersTantalum Pellet Co. & EmployeesJean and Kenneth TelljohannTennis League Network, LLCGoogle Inc. Charitable Giving Fund of Tides FoundationJudith Tinsley Foundation, Inc.Mr. and Mrs. Andrew H. TischSupreya TosakulwongAlain TranchemontagneMr. and Mrs. John TrousdaleU.S. Family Foundation Inc.Utility Contracting Co.Mr. and Mrs. Jeffrey K. Valentine Sr.Shirley A. Van ClaySharon and Cole VarvelRan VautmansJan T. Vilcek, M.D., Ph.D.Dominique von SiversRobert B. WalkerMr. and Mrs. Webster U. Walker Jr.Barbara WaltersCarrie L. WalworthJeff WareThe WarehouseCarol and George WatralLynne and Peter WeilThe Weingarten Schnitzer FoundationHelen and Tom WellingJulia W. WhitakerGerald I. WhiteJim WiattRoger WilkieNeil WilsonMichael WoinskyThe Woodworth Family TrustDoug Wright

Cancer Research Institute event, Palm Beach, FL


Dorothy WrigleyStephen YegelwelYoYoJam Inc.Raymond YuMr. and Mrs. Will ZeckendorfRalph E. ZerweckMr. and Mrs. Jeffrey Zucker

$500 - $999Anonymous (19)1-800-flowers.com, Inc.Kedar AbhyankarAcadian Asset Management LLCKenneth AdamsAnne and Richard AdlerAdobe Systems IncorporatedAduro BioTech, Inc.Advanced Research Systems, Inc.Sameer AgrawalAirtime ParaglidingFrancis AlbertCorinne E. AlexanderAmy AlspachAmerican Express CompanyTom AmpeliotisAmplifi Commerce, LLCGarth AncierJoyce J. AndersenKristine E. AndersonTerrill A. AndrewsAnnapolis to Bermuda Race Organization & Bacon Sails CompanyArcus Technology, Inc.Erik ArnetzScott W. ArnoneJohn F. AronsonMr. and Mrs. James AseltaStefan AumackArmond AvanesMr. and Mrs. Joseph AzaraMarielle BalzMatthew BanalCurtis K. BarkerCody BarringtonThe Bartholow Marital TrustBrian L. BartlettMary L. BartlettMr. and Mrs. Neil BayerMelanie BeardenWilliam D. BeattieDaniel BeatyNorman Beazer

Mr. and Mrs. Gerald BeckerGentry BeckmannChristina and Todd BeringerTom BiancardiDomenick BiancoFrances and James BittnerThe Boeing CompanyLaura BollmanMr. and Mrs. Brian BoonePaul BorutaKellye BowersJohn N. BradyJoseph F. BradyMr. and Mrs. Kevin BrennanMr. and Mrs. Michael BrennanStuart BretschneiderWarren K. BrewerLaura BrownMr. and Mrs. Paul A. BrownJost BrunnerCarla J. BuckDr. Marcia B. BullBundle Of HoldingRichard BuschMary CallawayJeffrey CalvelloMr. and Mrs. Liborio CampoLarry CantorThe J. Gregory Carl Charitable FundBrian CarrFrank H. CarrRandal L. CarterSaundra and Jim Castleberry and Tiffany HowardMr. and Mrs. Chris CesarShari and Daniel CharousChevron HumankindMr. and Mrs. Clifton ChilcoatChippewa Lake Community ChurchDr. and Mrs. Joonun ChoiChronicle BooksRobert CipolettiCiscoMr. and Mrs. Art ClarkR. Michael ClarkLeslie ClevengerJimmy ClidarasCoatproJacki and Robert ColburnNeil ColeAndrea ColemanMr. and Mrs. Bradley L. Coley Jr.

Mr. and Mrs. Erik CounterMr. and Mrs. Kelly CourterMr. and Mrs. Albert CovelliLisa Roberts CowellMaury CralleClark CrawfordMichael CroslynDaniel B. CullenRandi and Roger CunninghamJennifer Curtis-MauryEvelyn J. CusackSharon DahlhausLinda DainesJoni DanielBruce S. DarringerAlberta DavisKaren A. DavisJohn DelaplaneNicole DeLeonDelta Kits, Inc.Mr. and Mrs. DiamondMr. and Mrs. Michael D. DillonMr. and Mrs. David A. DivineGabe DonohoeDaniel T. DubbeldMr. and Mrs. Lance DunnStacey DurandLinda EdelcupJoel T. EdmanMarielle EmitEpic WinesDr. John R. EthertonFaye M. EtterExpress Employment ProfessionalsF & K Designs LLCF and MWL Enterprises Inc.William B. FaganMary FarrellPat FeezorFern & Fox GoodsDebbie and Paul FeuerbornJulie FinleyFitzgerald-Gates Family TrustWaldo FreemanMr. and Mrs. Bob FritzPatty FrykbergFulton Bank of New JerseySteve GableRami GabrielGorang GandhiCatherine C. GardnerWayne Gehrt

Scott GehsmannBarbara B. GentryJeffrey L. GentryKenneth A. GillGirls Raised in the SouthJoan E. GodwinDeidra GoldMarisol Gonzalez De CosioMr. and Mrs. Adam GoodmanMr. and Mrs. Ronald B. GordonPaula Gorlitz and Steven ZuckermanR. Raymond GorospeAndrew GouldNatalie Grace and Jacques DejouxGravy’s Bar & GrillPaul E. Gray Jr.Anthony J. GrecoRichard GreenChristopher M. GrubertJohn C. GunninAmit K. GuptaMr. and Mrs. Paul HaackAdeline HaggertyMargaret H. HamachekJacquelyn A. Hank and Timothy J. MuldowneyHank Lane Music & ProductionsMr. and Mrs. Robert HanscomG. Felda and Dena HardymonMr. and Mrs. Leonard HarrisonVictor HatamiMr. and Mrs. Michael HausMr. and Mrs. Frank HeflinJanet and George HeilmeierPaul C. Helmick CorporationLinda J. HendersonMr. and Mrs. Michael J. HerbstMarcia K. HerreraRita HertensteinStephen E. HerzogThemis P. HiosAmanda and Jonathan HirshonMichelle L. HoeslyMr. and Mrs. John HoevenerRichard A. HoffmanMr. and Mrs. Justin C. HolderHoneywell InternationalPhilip HoodJohn R. Howard Jr.Lori L. HoytRuth E. HubbardLaurie Hughes

Todd HughesJune and Tim HuntRobert C. HunterIllinois Tool Works FoundationNaoko ImaiDr. and Mrs. Richard ImbruceIn His Image Day Spa, LLCBill IndelicatoInvestigative SciencesNassar JabourDr. and Mrs. Theodore J. JacobsThe Jaffe Family FoundationViju JamesGeorge J. JarvisBunny and Ryan JeffriesCory JensenArthur H. Jerbert Jr.JMC Capital PartnersJames R. JohnsonMr. and Mrs. Lewis O. JohnsonJohnson & JohnsonJolliff RanchCynthia Lynn JonesHemant JoshiJerry KanterMr. and Mrs. Howard KayeRussell KempfMr. and Mrs. Nick KeplerJoshua KesselmanLeroy KimBetsy and Rob KingJean King and Stuart Appelbaum Lenore KleinDavid J. KleindienstAlex KlineSamantha L. KnapikDavid KnievelMark N. KochMr. and Mrs. Jeffrey S. KochelMr. and Mrs. Monroe A. KohnTetsuaki KokuraMr. and Mrs. Robert KooimanMr. and Mrs. Werner H. KramarskyJeffrey KramerTessa KramerMr. and Mrs. Ron KripalaniSriram KrishnanDoris KrysMr. and Mrs. Wayne R. KubickMr. and Mrs. Kevin KuntzMark KwanJeffrey LaHoste

Mr. and Mrs. Robert C. LakeDarren LamElizabeth LancasterMr. and Mrs. Charles LangdonMark LarrimoreGloria L. LeBlancMr. and Mrs. Alan J. LebowMr. and Mrs. Gregory P. LeeThierry J. LefeverMr. and Mrs. Marvin E. LesserEthan M. LevineRichard LevineMr. and Mrs. Arthur Levitt Jr.Grant LewisLincoln Financial FoundationLion Biotechnologies, Inc.Brian ListerDarlene Helms LopezDr. Dorothy L. LordKatherine M. LorenzDaniel M. LossKurt LouisMargaret LovelessGina LuppinoJoel MacIntoshMr. and Mrs. Jonathan C. MaldonJerome P. MalinayMass RelevanceAnn F. MatherBinu K. MathewMatthew Family Charitable Foundation TrustJohn MauroFrancis McCallJudith McGrathSean A. McMainsDerek McTyierSanjay MelwaniMr. and Mrs. Manuel MendesMr. and Mrs. Blaine L. MercadoAndrew C. MerrillMHRC, LLCScott MichellAngela and Ryan MillerMr. and Mrs. Mark A. MitchellSharon MontagueAnne B. and Allen Moore IIIDr. and Mrs. Malcolm MooreMarcus MordachiniCharlotte Moss and Barry FriedbergMr. and Mrs. Michael E. MozinaDr. Alfred Muller

Brian MurphyMUTISuman MysoreLily and Rodney NahamaMr. and Mrs. Uday R. NaikNationwide Credit CorporationJamie NaylorBrian NeaceNektar TherapeuticsMr. and Mrs. David NiehausRobert NorthingtonNuveen Investments, Inc.Nikolas OkaThe Om Center for Yoga & MassageJacob OreskyAdam C. OrfgenOswego Panther Soccer ClubVernon PankoninTodd A. PapaAnn and James ParkerPartners HealthcareMike R. PaskovichPatricia PaulaMichael PerkinsPharmaceutical Research and Manufacturers of AmericaPine Hollows Charity Fund Inc.Olga and Pat PiroDeborah A. PlattMary Polak and Lloyd SweetEric PolhamusShirley PonsartRonnie N. and William A. PotterStephen C. PrachtJason PreslarMarvin PriceRyan ProsserAdam ProujanskyMr. and Mrs. Joseph P. QuinlanLeesa S. RailsbackBeatrice ReddKristin ReidMr. and Mrs. Nicholas ReynoldsVirginia RiceMr. and Mrs. Andrew RichardsCol. and Mrs. James L. RoachJason RobertsSarah M. Robson and Stephen HarrisonRollGivingJames RosenthalMatteo Rossi

Mr. and Mrs. John M. RoweMr. and Mrs. Mony RuevenRichard SacconeDr. Kirk SaddlerMr. and Mrs. Geronimo J. SanchezSanDisk CorporationMr. and Mrs. George SarnerMr. and Mrs. Raymond SchansmanPetra Schindler CarterMark SchlauShirley SchmelzerArlyn SchneiderKaren and Henry SchneiderJudith SchwartzMarilyn SchwartzJane ScriptunasAshish SehgalMr. and Mrs. Richard SeidensteinKathleen and William SeiderJoel P. SeldenMr. and Mrs. Walter D. SewardBruce ShafferJonah ShapiroRebecca Sharpe and Peter BruckMichael ShelbyMr. and Mrs. Robert SheldonMr. and Mrs. Paul M. ShererJeffrey R. ShermanMr. and Mrs. Leonard ShermanMichael B. ShieldsShomos Family Foundation

Susan Crow and Tony Bennett at Through the Kitchen

Mr. and Mrs. Richard T. ShortChad ShuskeyMr. and Mrs. David T. SiegelMr. and Mrs. John SiffertSiler & Ingber, LLPJames W. SilverDr. and Mrs. Paul M. SimicErin SimmonsSimple Pleasures Rubber Stamps & Such, Inc.Anthony SingerSiteSaver/Penda CorporationRorie and Edward SkeiScott SklarJohn R. SlosarDaniel A. SmithCarolyn and Don SmithEllen and James SmithShirley C. Smith Charitable FoundationMr. and Mrs. Jonathan SokoloffMichael SpitzerMr. and Mrs. Patrick St. RomainThe State Bank of TexasMr. and Mrs. Richard M. SteinbergDr. and Mrs. Rishon StemerMr. and Mrs. James StensonMr. and Mrs. Allan SternThe Sternbergh FoundationSterndrive Engineering, Inc.

Eric StiffMegan StraussMr. and Mrs. Jan SuwinskiShawn TabinTara Tal and Aylon BrandweinMark TallutoMr. and Mrs. Kok Chor TanRyan TaylorRobert TeigmanTodd TestermanMr. and Mrs. Ronald A. ThalmannJorgen ThelinMichael E. TiffanyTrail King Industries, Inc.Julie and James TrantMr. and Mrs. Jeff TravisanoTriad Racing Technologies, LLCTrim-Rite Foods / Rantoul FoodsJudy TullieMr. and Mrs. Allen TurkCecile M. TurnbullUBSSuzanne and Donald van der KolkVarcoMac Electrical Construction Co.Veranda BeachAdam VitarelloJohn VogelNicolas Von Der SchulenburgJason L. Walker

Allan WartonMr. and Mrs. Edward WaxDorothy J. WehlageLinda A. WellsKent WerthRobert P. West Living TrustWest Michigan Academy of Arts & AcademicsMr. and Mrs. Gordon J. WhiteStewart WilsonJytte Winslow-MandleEdith WolfeSandra Wolin-BromleyMr. and Mrs. Ronald G. WollDr. and Mrs. Jerry D. WrightMr. and Mrs. Thomas M. YaminVladislav YasevichJane and Ronald ZimmermanTricia ZimmermanJane Zimmy and Ronald M. NeumannHoward S. Zinn

$250 - $499Anonymous (9)Mr. and Mrs. Todd AbramChristian AdamsJudith F. AduddellJean E. AeschlimanAIMC, LLC

Airtime Cafe, LauterbrunnenRandi AitkenDr. and Mr. Susan B. AlbaughMr. and Mrs. Louis AlferoMr. and Mrs. Shane AllenderMr. and Mrs. Lawrence M. AllevaAllianceBernstein AMAT CommunityAmerican Saturated FeltShaza AndersenElizabeth AndersonMr. and Mrs. Mark E. AndersonLarry AndreassenJohn AnzaloneARCO/MurrayArm, Inc.Aalia ArshadTimothy ArthurArash AsadiBilly AshRita AshMr. and Mrs. Steven S. AusnitMr. and Mrs. James B. AveryAXIS Insurance - E&S PropertyJohn S. BachBrenda K. BaconStephanie A. BadanesDr. Susan E. Baer and Mr. Bruce ThornburgSandra BaileyLeila BalaliSusan M. BaldiniJulia BailinTodd BaldreeMr. and Mrs. Joseph BankFlorence BaradJosh BargMr. and Mrs. Jeffrey C. BarnhillBarrett Glick & AssociatesLois I. BarthelEllen BaumRichard BavierMr. and Mrs. Burton BeamMr. and Mrs. Kevin BeausoleilMr. and Mrs. James P. BeckerJohn C. BegleyJack BelchDeborah BelcherMike BellRenate BelvilleBenchmark Consulting Services, LLCMr. and Mrs. Donald E. Benkeser

Mr. and Mrs. Chuck BenwittThe Berkley Group, Inc.Charles J. BernardMr. and Mrs. Anthony BernardiMr. and Mrs. Barry S. BernsteinCheryl B. BestermanJonathan BeteThe BGEKristen BirdNicole BissonRonald BlazekAudrey BlockChantal BlockPatrick BlockKyle BohanMr. and Mrs. Andrew BoldtBonanza Beverage CompanyGreg BorleyMr. and Mrs. Michael J. BoydMr. and Mrs. Royce BradfordMatt BradyHarry N. BraggMichelle R. BrasseurAdam E. BrembergerScott BrennanMr. and Mrs. Jason R. BretzBeverly G. BrodioiMr. and Mrs. Michael C. BrooksKeith W. BrownKathleen E. Brown-HallDomenique and Jonathan BuckTerri L. BuckleyEstate of Anne Luise BuergerBuildASign.comPatricia BurkleyAlexander C. BurnsideLeslie ByelasThe C.A. Cushing Charitable Gift FundMr. and Mrs. Robert A. CalderClark CallanderMr. and Mrs. Jon S. CanaleJames CanavanDorothy CarderDr. and Mrs. John CarinoDelna CarruthersMr. and Mrs. Gregg CarvilleMr. and Mrs. Norman R. CashMatthew D. CasnerCasto Travel - San FranciscoCatholic Family Insurance ServicesTara C. CavanaghCertain Affinity

Annette L. ChaiAlfonso ChangOlivia ChauBeth Ann ChilesNeeraj ChouhanLyle M. ChristensenJames ChristopoulosMr. and Mrs. Marc CinqueCindy CinquinoRobert ClaytonMark R. ClaywellAdam ClemensLindsey and Evan CohenAntonio CokovskiDr. and Mrs. Bobby M. CollinsFrances S. CombeJudith ComroeCongregation Beth Torah Executive CommitteePeter H. ConnellyConveyor Sales CompanyJohn CoonlyCece CordRev. Sara Cory and Rt. Rev. Thomas Stephen L. CotterJane and Stephen CouttsKerrie I. CozicKathleen CraneDr. and Mrs. Neil CrellinMr. and Mrs. Robert CrisalliAndrea CroninBruce M. CrowellGail CruzGrace CruzKatherine L. CuccoDonald C. CurtinCVAR Drivers and FriendsMr. and Mrs. William M. CzarnowskiJerome A. DabrowskiJason J. DaCostaDalby, Wendland & Co., P.C.Louis D’AmbrosioMarla S. DanielsMr. and Mrs. Rodger D. DanielsAndrew C. DawsonRobin A. De RosaMr. Andrew A. DebenedictisMr. and Mrs. David S. DeckerJohn DeckertDecorative Rock Sales, LLCTony DeCrostaJoseph Del Vecchio

Mr. and Mrs. Doug DembowskiJames DennisGino A. DePalmaMr. and Mrs. Kevin DerschJon DeutschRichard DevineMr. and Mrs. David DiamondJenea DiamondFrank DiGiacomoBruce D. DixonDoctorDirectory.com, Inc.Elizabeth A. DolezalJohn DonahoeDonahue & HorrowMr. and Mrs. Mark DoneganMr. and Mrs. David L. DorenfeldMr. and Mrs. Jay L. DotyMr. and Mrs. Alexander H. DowMr. and Mrs. Arthur V. DoyleRuta G. DudenasMr. and Mrs. Michael J. DunnPaul DunnMargaret DurneyMr. and Mrs. Stuart DutterMr. and Mrs. Douglas DuttonKaren C. DyerEastern PerformancePeter EdgeMr. and Mrs. Thomas C. EdwardsChristina El MoussaElectro Rent CorporationMr. and Mrs. Alan G. EllisMr. and Mrs. W.J. EmersonEnvironmental Service Laboratories, Inc.Richard A. EnzEquifax FoundationESAC, Inc.Michael FaccioliDr. and Mrs. Angelo FalconeLillian FarrellAnthony D. FawverFaze 4 OrchestrasBruce FefferAlexis FeldmanDana FeldmanNancy FellerKate FermoileBeth FerrellMr. and Mrs. Richard R. FettermanJennifer FieldCarol J. Finney

Walter FischMr. and Mrs. David FischerShirley S. FisherMatthew FlagerFleet HillFletcher, Heald & Hildreth, P.L.C.Tyler FolckPatrick J. ForanGary H. FormanEdward FornataroAlan W. ForrestFranklin Display GroupChristie L. FraserFredericksburg Chapter #29 Order of Eastern StarMr. and Mrs. Howard S. FriedmanStephen GaddyMark GalloglyEsther GamezAlizeh GangjiThe Ron and Debbie Garrow Gift FundMr. and Mrs. N. Pierre GastonGastroenterology Consultants, P.C.Mr. and Mrs. Todd P. GeismannGeneral Reinsurance CorporationRebecca L. GentryRosemarie GenualdiMr. and Mrs. Scott M. GerardIlias GerontidisMr. and Mrs. Vishal GhiyaMr. and Mrs. Umberto F. GianolaMr. and Mrs. Charles GillisC.W. GillulyGirl Scout Troop 824Mr. and Mrs. John GiumarraMajor P. GladdenElliott GlassMichael GlicksteinGo Go Gatsby Designs LLCLaurence GoldfeinScott GoldmanMr. and Mrs. John K. GoodmanA. GordonPeter GoyneJohn GradyJohn GrayHelen A. GreenMark GreenbaumAlyssa GreenbergMr. and Mrs. Wallace D. Gregory Jr.George GrisetMr. and Mrs. Ron Grizzard

CRI trustee Bob Dahl (right) with winning foursome members at the 19th Annual Golf Challenge, Sebonack Golf Club


Susan M. GudmundsonGumahad Family Gift FundYujie GuoMr. and Mrs. Walter GuyMr. and Mrs. Matthew HaiesEugene HallVicki L. HallJanet L. HallaJeremy HalperinYasuhiko HamadaMr. and Mrs. John A. HamiltonBonnie HammerL. Karen HammerDavid HarrisonBrent A. HartGreg HartWillard L. Hawkins Jr.Martha M. HaywoodSteven J. HeckerDavid HellerMr. and Mrs. Lawrence HellerPaul T. HempelElizabeth HeroldMr. and Mrs. Allen HerskowitzMichael HessHFO Investment Real EstateJanet K. HiseTerri L. HodgeDr. Alexis G. HoenAndrew HoffmanLeca J. HolderBradley W. HoldridgeEdna Jo HoleHolland Meadows Golf CourseGrace D. HoltBen HolzemerSandra HorbachMr. and Mrs. Michael G. HornerSteve HostThe Wallace and Janice Houchin Family TrustDr. and Mrs. Alan HoughtonMr. and Mrs. Billy HowingtonSharon E. HoytMaojen HsuDr. Douglas E. HughesHull & Associates, Inc.Hon. and Mrs. Russell L. HumphreySarah HunterEric R. HwangIllinois Education Association Staff Organization

Stephen ImperatoEugene InterlandiTheodore A. IrraIzzo & Son Country Gardens LLCSherri JacksonSandra J. JacobsonRenee JaffessMartin JanisJanklow FoundationJLK Rosenberger, LLPCheryl JohnsonMr. and Mrs. Keith JohnsonValerie A. JohnstonHubert JolyJessica JonesJulie L. JonesPreston JonesStephen JonesVictor Jongeneel, Ph.D.Arleen S. KaganDr. Michael KahnJess J. KajiwaraKaplan Fox and Kilsheimer LLPPeter S. KaplanTimothy R. KarcherMr. and Mrs. Mark KavanaghPatrick P. KaylorKeenan, Hopkins, Suder and Stowell Contractors, Inc.Lynette KelleyKevin A. KendallPatrick KennedyTom KennedyPatricia K. KeyKeystone Clearwater SolutionsRobert KielyRichard KillKelleyKimmel & Kimmel, LLCTheresa KingJill R. KinneyAdrial KirchenCameron KlingerRoger M. KohlerTerri KoubaDiane G. KranzMr. and Mrs. Harold R. KrivinsArnold KuennDmitry V. Kuprash, Ph.D.Mr. and Mrs. Brad R. KussyBobby LabonteMr. and Mrs. Bob LaemleJason M. Lai

Mr. and Mrs. Lester LaiEdward C. LallyMatthew LaMannaThomas LampertJeremy M. LandmanPeter Lanelashavingsoap.comKatelyn LauMr. and Mrs. Frank LavoratoMr. and Mrs. Wilson S. LeachLisa A. LearmanChristopher LearnedMr. and Mrs. Thomas M. LebeauHoa T. Le-ResnickMichael D. LesherMichael S. LesserPaul LevesqueMr. and Mrs. Robert S. LevyMr. and Mrs. Mark H. LichtHilary LindahlMatthew LindblomPeter A. LindleyMr. and Mrs. Bruce LindquistRichard LipskyJacqueline LiuDr. Stephen LiuDominique Lock Wah HoonLoewy Law Firm P.C.Jessica LondonLone Star TransportationLong & Associates, AIA, Inc.Mark E. LongworthZen C. LuMr. and Mrs. Richard M. LucasMr. and Mrs. John S. LuckstoneRichard LujanGail LundTyler LundMichael LyntonLana LyonMr. and Mrs. Ronald LysloM.A. Primary & Urgent CareEdward MaJacqueline MacDonaldFaith B. MackayMr. and Mrs. David MadsonVivian Maese and William Bannon Anneliese MalewiczVictoria J. MalmgrenSrinivas MandadapuJames J. ManningMarlene S. Manning

Kallie MaranoNicholas MarchiAlim A. MarediaMichael F. MarekBrett MartinM. Jean MartinJames MarzolinoMark MasciaRenny A. MaslowJamie Mason and Paul StaggMr. and Mrs. Jari MattilaJeffrey S. MayMr. and Mrs. Danny McCallBritt and Sean McDonnellVictor McFaddenHugh McGaughyJane McLaganCiara McMahonRobert C. Meade Jr.Mr. and Mrs. Steven A. MeccaRajeshwari MedamAda MeloyMr. and Mrs. Douglas I. MelsonSamuel MeltonMr. and Mrs. Simon MencherMentor Graphics FoundationRenea MertensMETCOR Ltd.MeteorixArthur N. MichellMidfirst BankMidwest Industrial Metals Corp Inc.Military Sealift Command Combat Logistics ForceGary R. MillerMr. and Mrs. Glenn A. MillerVicky MinnetiMr. and Mrs. Harold S. MinoffElayne and Barry MischnaBismruta Misra and Bill DouglassKevin A. MistryMr. and Mrs. Larry MitchellPeter B. MitchellRita MochelRichard MoffieMr. and Mrs. Jeff MontagueAdelina M. MooreDeborah L. MooreJohn MorenoM. Carol MorganMr. and Mrs. Paul MorkenJo Morris

Andrew W. MorrisonDr. and Mrs. Michael MosesMount Hope Trucking CompanyNaomi MoyA.J. MuldoonLilac MullerPatrick J. MulrooneyMr. and Mrs. Jignesh NaikAnnette NasifElaine NeelyCraig E. NelsonMr. and Mrs. James G. NelsonKaren R. NelsonEllen G. NewmanLinda NewmanPatricia NewmanPhilip NimmoHoward NizewitzDeborah Norville and Karl G. WellnerJohn NowakGail Nyari-LazzaroDr. and Mrs. Craig OlinSandra OlsonOne to One MD, P.A.Jon OringerMaxwell D. OsborneMelissa OstroffNestor PachecoJustin A. PaganoPangRick H. ParaKate ParkerMr. and Mrs. James E. ParrishMark ParsonsMichael PashkowBrian A. PasquinelliMaria Rodriguez Pastor

Amrat N. PatelDhanashri PatilAndrew T. PatsinerDavid J. PaulPatrick PayneMr. and Mrs. Scott H. PeaseAndreas PecherNorma and Jerry PerlmanDr. and Mrs. Bruce PerryDerold F. PerryJarel PerulloAllison PetermanPfizer FoundationClaire M. PhillipsHeather M. PhillipsPinckney Community SchoolsPinnacle Property Solutions, LLCDr. and Mrs. David PitelDr. and Mrs. Robert L. PlanksyMr. and Mrs. Richard PleseMr. and Mrs. Robert PompeiDavid PortnoyLinda PortnoyAaron PoslunsDr. Matthew H. PowerRichard A. PowersJohn V. PridjianMr. and Mrs. Alfred J. PrinceThe Progressive Insurance FoundationPrudential FoundationTaylor PruisnerDemi PyshMr. and Mrs. Edward I. RabinEric S. RadfordEstate of Aspasia RadoumisPaul Rago and David SmallMr. and Mrs. Glenn Rankin

David M. RappaportKristen RathfelderJenny RavenscroftEdmund ReckRecover PaintingMary Y. RedmanMr. and Mrs. Daren V. ReidMr. and Mrs. Jared ReillyMary Ann ReinhardNancy RelefordMr. and Mrs. Edward R. RenickerResource One International, LLCDr. Debra ResslerKenneth J. RevisRex Energy Operating Corp.Dale C. ReznyIra Rhea, M.D.Christopher RichmondAnna RobertsJohn Roland RobertsDr. Andrew RobisonMr. and Mrs. Jeremy RochellJohn C. RockwellGeorge C. RoethAndrew RogersMr. and Mrs. David J. RossoDr. and Mrs. Guillermo J. RozasBernard M. RupeKevin RussellKristin RuthbergMichael SalsaLawrence E. Samelson, M.D.Stacy SanchezScott SandsJane SaperyChristina ScannapiecoHeather R. Schank

Melissa A. SchmittMr. and Mrs. Jon C. SchmitzMr. and Mrs. Theodore SchnitzerTim SchoeckRichard E. SchorseMr. and Mrs. Michael J. SchreinerBarbara SchuetteMr. and Mrs. Kenneth SchultzJohn F. ScolioUrsula SearcyMartin SechanTom SeclowGreg SedlockSegal ConsultingGeorge H. SellersSepta Human ResourcesZig SerafinRalph SerpicoCraig SeteraMr. and Mrs. Saleh ShahrabaniReva SharmaMary M. SheehyJosh SheetsPaul SheltonDr. and Mr. Robyn ShepardsonMr. and Mrs. Jesse ShereffHiroshi Shiku, M.D.Jeffrey ShoreThe Shumway FoundationMr. and Mrs. Joseph SidariDonald Siegelaub Revocable Trust AgreementLisa SiegmanBrendan J. SihksnelDean SimcoeMr. and Mrs. Gerald SimnacherMr. and Mrs. John D. Sipes

2013 Marine Corps Marathon Team CRI members gather for a shared dinner on the eve of the event

Hamza SiragDr. and Mrs. Ian K. SlepianChristine Balko SlywotzkySmall Planet FoodsRobert H. SmithJudilyn L. SomeraSugi H. SorensenMr. and Mrs. Marco L. SpadacentaJohn SpanoChristine SpeareSharon SpearsSpecialty Tile ProductsMr. and Mrs. Irwin SperberRamona SpiegelNorman SpielerMr. and Mrs. Joseph M. Spillane Jr.Vera K. SpragueJohn R. SquierSt. Catherine ParishMr. and Mrs. Murray E. StadtmauerLee I. StahlGeorge C. StamatelatosEric B. SteelMr. and Mrs. Aaron SteimleDr. and Mrs. Charles R. SteinbergMichael J. SteinerSherry S. SteinerHillary SternDaniel F. SterneSteven M. StitesMr. and Mrs. Jonathan StockdillJoseph E. Stockwell Jr.Ashley StokesCarol S. SullivanKathryn SullivanMr. and Mrs. Leo J. SweeneyDavid SwensenRobert J. TaetschMr. and Mrs. Aaron TagHaruyuki TakakiScott W. TalbertDiane Tannenwald and Jim GrishawTennyson Family FoundationRebecca L. TerleckiChristopher TerrasseAthalie A. TerryMr. and Mrs. Thomas TerwilligerEan Choo M. ThamMr. and Mrs. Ernest L. ThomasJames L. ThompsonSarah TippleMr. and Mrs. Anders Tjernlund

Sarah H. ToasLeslie Toepfer and Charles J. HechtRonald A. TornowToyota Financial ServicesToyota Motor SalesDr. and Mrs. Phillips B. TrautmanTravelers Community ConnectionsKenneth M. TravisThomas S. TrovatoKuang Liang TsaiJames B. TuckerMr. and Mrs. Jeffrey TuckerPeter J. TvarkunasTVHS, Audiology & Speech Pathology Svc.Judith A. UdellUnited Technologies Charity Trust Acct.University of Florida’s Honors Without BordersStanley UrasakiUtheverse, Inc.Mr. and Mrs. Robert H. VadenPatrick C. ValentiNancy Van TuyleLucas C. VanDeWieleMr. and Mrs. Daniel O. VanwormerMr. adn Mrs. Otto J. VitaleVor VudthithamrongVictoria WagnerYichun WaltzerRebecca P. WardMr. and Mrs. Jeffrey B. WarnerWarrant Officer Staff Course 14-F02Peter WatsonJustin WebbDennis WeissEmily WellikoffStephen A. WellmanMr. and Mrs. Geoff WhislerMichael W. WhiteCharles WiegoldDr. Carmen S. WilsonMr. and Mrs. Kevin WilsonMichelle WilsonWilson Construction Co.Lawson T. WinslowDr. Anne WolfeNancy J. WolffAvon WonderlyBarbara F. WoodJudith Wood

World United LLCJoyce WorthingtonKendall WrigleyJ. WuTsae WuMr. and Mrs. Michael C. WyumYufen YangYared Yawand-WossenJoel M. YesleyJanel A. YorkLiana E. YoungLesley K. YuOliver Z. YuMr. and Mrs. Sunny YumLeora Zach and Elias YoussefZachys Wine and Liquor Inc.Zadok JewelersDr. Virginia A. ZakianMr. and Mrs. Richard ZappalaMr. and Mrs. Nick J. Zarvos

Endurance EventsIn FY2014, Team CRI helped raise funds for CRI by participating in the following endurance events.

2013 Marine Corps MarathonDiane BakerRichard BavierMike BellSean BurnsAlexander CovenJodi Cull-HostErica CuriNeal DennisonErin DreuxToni ErwinGreg HartAlex KlineMelissa Knievel-NatansonDana LarsonBrian ListerJason NatansonJackie O’BrienGesine PradoBret SalmonsSarah Shriver

2013 ING NYC MarathonBlanca AveryJames M. CitrinPeter Coley

Brett Frykberg Naoko ImaiPeter Bradley MitchellJames NunanWilliam PachecoShruti RaoFred ReedeDanielle RuthbergKristin Ruthberg

2014 NYC HalfMichael BillottiTimothy CollinsTorz DallisonNicole DeLeonJenea DiamondAngelo GiordanoAndrew GouldForbes HuangJudith JonesJessica KalishMarilynn KaufmannJoshua KushnerAndy LangeLana LeeJohn LeeJennifer MarcusAmanda MathiesonElaine PetitRobert ReustleLilian ShepherdFrank SimoElizabeth StevensonLana Sze

2014 TD Five Boro Bike TourSusan BerkleyRenee BermanMichael GilroyPaul McDowallGregory RobinsonDaniel SchneiderLuc VautmansRan VautmansWalter WeilYared Yawand-Wossen

Community FundraisersTeam CRI allowed friends, families, and companies to raise funds together in their communities in fiscal year 2014.

ACIRAlcatraz Swim 2014Saad AliEvelyn AltonAmscan Inc.Asil Fights CancerGina BelkaKarl BelkaCaron Bevard and Giovanni JonesAndrew BloomPenny BoltonJanara BostickChris BowmanJessica BowmanSteve BradfordThe Allegra Levy Brooks Revocable TrustMichael BrownCarla BuckMr. Paul W. Camarda and FamilyCancer Wilderness WarriorsBrian CarruthersPooja ChandwaniKate Claas and Mark Goldman Julianne ColemanSteven ColemanChris ConradAnna CottonMarian and David CourtenayJohn CrookMariely CrowneCruising for a CureWhitney DardenEthan DavisTess DoyleLucas DurneyChad EbyExpress Employment ProfessionalsRobert FarrellAndrea FerdinandFootprints for PeaceLiz and Claire FriedmanAntonina FrolovFrontier CommunicationsFulton Bank of New JerseyManjit Gardner

Ryan GerberMark GodseyGravy’s Bar & GrillLydia GreerNikki GrimmDonald Guernsey Jr.Isaac GuerreroSarah GunterRobert G. GuthrieDavid HadderPayton HeimbachHolland Meadows Golf CourseEthan HolmesJeff HornIllinois Education Association Staff OrganizationIn His Image Day Spa, LLCInfinite ContinuesSimon IngoldIronman Foundation, Inc.Robert JenkinsJordan JonesKevin JosephsDasha KlyachkoCharles KukesKustoms for a CureRichard LandesmanPatricia LauryCassandra Lee MatosJeanine LizotteKatie LopezZach MartinezCarson McBainTammy McGowanMegan McLeesDavid MinLisa MiragliuoloMontgomery County 4-H Beef ClubNeal MuldoonErin NorrisHeather OkenkaJohn OkenkaCatherine OrrBarbara O’ShaughnessyMatt O’ShaughnessyMatthew OsieckiAnne PaceCandy PaceAlex ParodiJoel PaulaNichole PellettWilliam Penney

David Courtenay, with his wife, Marian, made an 800km trek throughout Spain, raising nearly $7,000 for the Cancer Research Institute

Portfolio AdvisorsDevin PriceRenee PriceTucker PriceRachael QuickR ZeltzerThe Right Hand of DoomSherriff RobertClaire RosensteinRubberVoltz Modded Minecraft ServerJoan RyanEmma SaundersTim SchoeckMara SedlinsSarah Helene SharpColin SheehanShowin’ for a CureSue Anne SmithWill SmithErika Spitzer and Zach FriedlandChristina SternAlex StolleCaroline StolleEdward StolleKevin StolleTricia StolleStudio Twelve Hair Designers LLCJeff TakeoverTeam BrownTravelers Bond & Financial ProductsBill TritschCarol TritschChristine TritschNikki TritschUtherverse, Inc.Andrea VorpahlHayden WendelEmily WigginsEwing WilliamsSarah WinklerDane WrayYoYoJam Inc.Zachys Wine and Liquor Inc.


Helen Coley Nauts SocietyThe Helen Coley Nauts Society recognizes donors who have included the Cancer Research Institute in their estate plans. Through deferred gifts, bequests, trusts, and other planned giving instruments, these thoughtful individuals safeguard the Institute’s financial future. The Society is named in honor of Helen Coley Nauts, CRI’s founder, whose passionate belief that the immune system could one day be harnessed to control cancer has helped make this powerful vision a reality today. To learn more about making a planned gift to CRI, please contact Emily Livingstone at [email protected], or call us at (212) 688-7515.

Anonymous (5)Estelle AbasPeter AdamsAbigail AldermanOlga AleskasMildred E. AlexanderFrederick E. AllardEdith M. AmateauPeggy AndersonFrances AntopolFreda S. ArmstrongGrace ArnoldGeneva A. ArthurRuth AscherVirginia and Rex AshdownLee AsherBelle AshermanAlice AuerbachNorman W. AustinJeanne AvegnoElse BaierOlga BakerMarion BalenElla R. BanksMary R. BaqueDorothy BarbeauJeanne E. and Jacob A. BarkeyMr. and Mrs. Kenneth BarmoreWilliam BarrFlorence and Ben BarrackRose BarrowIsabella Williams Bartholow and Bruce Burdette Bartholow

Etta BaumEvelyn BeekmanFrank L. BellGermaine BeneschWilliam A. BerkeyStuart BernardLucille BernotHerta J. BernsteinVincent L. BesseyGrace M. BishopJohn BittelGuy BjorkmanLeslie J. BlainAnna H. BlanksteinPaula J. BlatterRuth Evelyn BodbylEleanor BodnarRonald J. BogusNancy E. and Lawrence H. BonanderMary BorbeckRita BorensteinRobina C. BouchardAnna Isabel BoydHugh R. BoydBarbara Brown BoyerFrederick BrandJoy B. BreidlingLucille BrentsA. Arthur BressmanBrian M. BrewerVictor E. BrollAlbert N. BrooksMinnie E. BrownVirginia BrunerAlfred R. BrunnerEstate of Anne Luise BuergerLucille A. BulandMary C. BundyArthur BurkhardtLois M. Burns and Robert W. Burns Dale T. ButterwickJoy Biggs ButtleTracy CampbellAngelina CarboneAlfred CarlucciJulia CarlucciPandora Rudland CarrollDonald O. CarswellMelba CaseMary Elizabeth CattoDoris M. ClaninWilliam James Clapp

Rodney CobbWilliam H. CoffeeBernice CohnGwendolyn ColburnMr. and Mrs. Raymond ColeEdythe E. ColemanBradley L. Coley Jr.Louis ComedyPhyllis L. ConleyVivian E. Conner and Ross I. ConnerLottie M. and Charles H. CookSalvatore CorsaroAudrey CowanEleanor H. CromleyElmira CrosbyJulia B. and John R. CurtisVincent D’AmicoAnnabelle L. DanzigCarleen DavisAlice DawesAileen Adele De LongEustis DearbornEmma DetersBetty DisbrowAdelaide J. DodgeSandford DodyMary Ann DrausBlanche Elizabeth EckertsRita EggertDorothy M. EiserEarl R. ElliottPauline E. ElliottRuth EngelbergValera L. EnnisHelen EpsteinNathan EpsteinMax G. EriksenHelen B. EsokaitFlorence L. and Ned A. EtkinJuanita M. EvansMary S. FadeleyHelen Jean FalkHerbert Lynn FannBarbara FeldmanRobert I. FendrichCarlos A. FerrerAdelaide E. FerrisLouise Egdorf FescineElsie K. FilonchikMary H. and Frances E. FloodJosephine FontiFlorence A. Forni

Bernard W. ForrestCarole D. FranklinClay FrazierLucille O. FrenchAlice M. FriedAnne FruhnerLena Silverstein FuhrmanGay H. GahaganZoltan GaldiEugene G. GallantPeter GallantMollie E. GangSophie GarafolaSalvador GarciaCarole GardnerB.I. GarlinghouseE. Yvonne and William O. GeisertStella GentileMildred GentryPenelope M. GeorgiadisMercedes C. GerhardPatricia J. GetsfriedJanet M. GiffordRegina GilmourSteven GinsbergEdna E. GlaesselEleanor GoldbergPhilip GoldblattRaymond J. GordinierDoris GordonJean R. and John G. GosnellNorman GottliebDorothy M. GrahamE. Ruth GrantAnnette and Owen GrayBernice E. GrilleauxFloyd Dale GrishamZoe S. GroveRonald J. GuglielminoMarianne C. HafnerJeanine HairNelle B. HaireAdrian Leroy HallDiane HamMr. and Mrs. Virgil HambyFrances E. HannemanThe Hansen TrustLydia C. HansonLoretta D. HardyMark L. HaritonEvelyn H. HarrisLori Harris

Ottis C. HarrisHelaine T. HarrisonYetta HatchAnne M. HauserJames Leon HawkinsMargaret HaymanClarence E. HedbergDonald P. HeimVirginia HemmeRobert J. HendryFredrick Charles HenneSenora HenryMarion HewettKay HiltonMargot HoffmannNurine HokeDiane and Don HolmesEva M. HolmesNellie HuffGrace M. HumphreyMary L. HutchinsIdell E. and Fred W. IltnerMadeline InguagiatoRuby R. JankiewiczLynn and Eldon JasperWarren R. JecklinDoreen and Basil JoffeRuth Harvey JohnsonDoris KabatRosemary KaplanSally J. KaplanSara KatzBertha E. KaufmanSamuel KayBlanche C. KellyJean KempHugh W. KennedyMercedes E. KentElsie E. KielCorinne KiellTheresa A. KielyMary B. Kilroe and Edward L. Kilroe Barbara KincaideHilda KirsonShirlene KisakMarilyn and Robert KlettRuth and Hugo KlotzAnne KochTruby Joy KohlMr. and Mrs. Harry KompanekJuanita and Fred KoorsHarry A. Kraus

Mary T. KrausNaomi P. KruseMurray KupfermanHiroko KyubaRose LachowSidney G. LaDueAnna LagsteinC. Linda LambertJewell Marie LampkinMarguerite LandisLouise G. LaneCaryl Lou LangfordElizabeth S. LarkinAnneMarie LaValleFlorence and Edgar LesliePolly Annenberg LeveeJames F. LevensFrances LeventrittBetty Lou LevinEsther LevineBeatrice LevySimon LifshatzFrancis R. LindenHarvey A. LindenPatricia A. LindnerGeorge H. LindskogRoseline LissakJohanna LoebRuby Q. LokensgardPeter J. LommenBonnie LongAlbie A. Adams LovingMadeline LukowitzMr. and Mrs. William H. LyfordGertrude A. LynchHjordes Diane LyttleEleanor D. MacCrackenEmilie MachalinskiCatriona MacleodWilliam S. MaddenboroughDavid MadsenFerne MagialardoHenrietta MalbinHerbert J. MaletzIsabelle C. MaloneAnna MalowanyJohn Malowany TrustMeyer MarcusB.M. MarinkoGenevieve MartinLouemma MartinLowell A. Martin

Raleigh L. MartinBlanca Mattalia-WyrzykowskiMildred G. MatzMargaret MazzeyMichael I. McBrideHelen McCannCecil McClernonAnnette McDonaldJ. Donald McKinney Jr.Norma J. McPhersonJan MearsGrace Muriel MecchiNancy Jeanne MerkelSidney MeskinEthel L. MeyerEzilda MichelHelen T. MiddletonDorothy Mae MillerWilliam D. MillerMaxine and Charles MindlingAlex MitchellMr. and Mrs. Charles G. MooreJanet P. MorganMaza D. MorrisLouise and Peter MoseychukBryant A. MuenzenAlexander MunchweilerIrene R. and Martin F. MurphyJudith K. MurphyKathryn T. MurphyThomas P. MurrayNaomi MyersMayumi Nakagawa and John K. LaiRita NasserAlice A. NautsPatricia NavarroPaula M. NealBarbara Lynne NelsonRose E. NelsonJean Marie NewcomerFreda E. Newton and William E. Newton Herb H. NicholsBernard R. NiewoehnerGeneva W. NolenJacques C. NordemanMary M. NowakMary NunezDorothy B. NurickMargaret M. and Harry A. OakNora OdetsArvilla Ogden

Helen Coley Nauts, D.Sc. (Hon.), Founder, Cancer Research Institute CANCER RESEARCH INSTITUTE 2014 ANNUAL REPORT 43

2014

FINANCIAL HIGHLIGHTS

MESSAGE FROM THE CHIEF FINANCIAL OFFICER

In the link below, we provide detailed financial statements for the Cancer Research Institute (CRI) for fiscal year 2014 (July 1, 2013, to June 30, 2014). The graphics above illustrate a breakdown of revenue and expenses in both real dollars and percentage for the same period.

We at the Cancer Research Institute hold accountability, transparency, and efficiency as core values in our work. As a result, we devoted more than 88% of our operating expenses to programs. In fiscal year 2014, this meant that we invested more than $22 million in research and education programs. The 2014 financial highlights are above.

To CRI’s friends and supporters, we thank you for your contribution as we work to fund science that will have the most impact in bringing cancer immunotherapy to more patients. Together, we will conquer cancer.

View our audited financial statements at www.bit.ly/CRIfinancials.

Alfred R. MassidasChief Financial Officer

PUBLIC SUPPORT & REVENUE

$27.5MMOPERATING EXPENSES

$25.0MM

Administration$1.0MM, 4%

Marketing & Fundraising$2.0MM, 8%

*$19.2MM awarded minus $1.2MM in early terminations from grants made in prior years

Education$4.0MM, 16%

Research$18.0MM*, 72%

Special Events$3.0MM, 10%

Investments & Other$3.2MM, 12%

Contributions$19.1MM, 70%

Bequests & Memorials$2.2MM, 8%

Michele A. OgnibeneRoselyn R. OlkenAlice OrlichMary O’RourkeAnna and Paul OschwaldAlbert OttingerLilly E. PaceLily Pace and Floyd Pace Marjorie W. PackwoodErma N. PanfilioAndrew Reid PatonEleanor T. PattersonCarmen F. PattiFoster Clae PattonFrederick V. PayneNancy Elizabeth PeaseApril PeckDonald H. PeperAgnes PhelpsElizabeth F. PhillipsJohn PiercyHarriet-Anne PiersonRochelle PinzCynthia Joy PlattDorothy PlumbMabel PlunkettNick J. PokeaDavid M. PolenEsther PosinRichard PotruchDespina PoulosClifford PreskyJoyce A. PrimeDorothy S. PritchardAspasia RadoumisCarol Diane RankenJames B. RansohoffEsther ReedHarry Delos ReichHelen RelkinFloris J. RenkLaDonna ReynoldsJames F. RiceFlorence V. RichardsonAdam J. RichterVirginia L. RiddleRobert T. RidleyAdeline RingeisenDr. Fred RingelVeronica A. RoseSusan RosenbergMoises Rubiano

Dorothy and Ernest RueppelGloria RuminskyHedwig SalzerLydia B. ScannellMartha SchnellerVirginia SchuettpelzHelen R. SchuttRuth SchwartzmanRev. Harold Bend SedgwickDorothy K. SefcovicClara SenkNatalie ShebsDorothy M. SheeseMargaret SheetsDonald SherwoodRenee and Irwin ShishkoLaura M. SidenerLottie SiegelKatherine U. SilvaBelle V. SilversteinAugusta SimonRoma SinclairEstelle SingerJean V. SirlesAlice Jean SmithCatherine M. SmithClarence SmithMr. and Mrs. Ernest B. SmithHoward G. SmithKevin L. SmithPatricia SmithWillie Mae SmithRuth SneveVera Marie SniderEsther and Harold SohmerFred E. SpencerJacqueline SpencerWilliam SprengerRemy R. SprouseBrenda M. St. JamesGerald J. SteinbergLeopold SteindeckerAnna StephanRobert L. StevensMary Malcolm StilesFay Strout and Laurence Cecil Strout Frieda Coons StudleyDorothy H. SullivanMyrtle B. SummersAgnes Katscher SunleyJohn SuponMary and James Suthard

Mary Carol TalericoMaureen TannehillCarl E. ThomasGeorge C. Thomas Jr.Geraldine E. ThomasOverton Arnold ThompsonViola Mae ThompsonAnita and John R. TimmelCarola S. TrierJessie C. TrippJohn D. TurkelZelda M. UthePaul E. Van CleveWilliam R. VassJosephine S. VillemanMyrtle H. and Antone L. VinelliAnne D. VintonLinda VonoEsther and Stanley WadeEthel WagnerDavid WalkerRobert B. WalkerThomas WalshJulia WalzLea WardIrene M. WatkinsDorothy WaughIone A. and Albert L. WeickertRose C. WeiselElizabeth A. WeiserLeonard WeissRobert P. WestAnna M. WheelerAgnella L. WidmerGeneva K. WidmerMargaret WiegandtSaul J. WienerLoretta M. WigginsLorna Katherine WilkinsonHarriet B. and Francis I. WilksJosephine H. WilliamsOra Brown WindleMr. and Mrs. Norman J. WoodhamsFrederick W. WoodworthJohn A. WoottonJosephine WoottonNettie WrightEthel R. YoungMarion E. YoungbergGloria ZainoMarion Zell

Centennial CircleThe Centennial Circle celebrates donors who have made a lifelong commitment to supporting the Cancer Research Institute. Members of this loyal group have made 75 or more gifts to CRI during their lifetime.

Ellen BeloffMr. and Mrs. Ira M. BoskeyLauren B. BurnsHarriet E. CharlesMr. and Mrs. Irving CohenSelma DavidsonMr. and Mrs. Stephen C. ElkinRhoda FischmanAnne E. GentileMr. and Mrs. Gary R. GinsbergMr. and Mrs. Leonard GoldHelen A. GreenRenee A. HarrisHarvey A. HerbertMrs. Stephen M. KellenMr. and Mrs. Elliot LeitnerMr. and Mrs. Michael LevyCharles J. LurieMr. and Mrs. Charles Lyttle IIMr. and Mrs. Arthur NassoJacques C. NordemanEsther RavinMr. and Mrs. Jonas J. RieterMr. and Mrs. Milton S. RubinClifford M. RutterMr. and Mrs. Sydney ShumanMr. and Mrs. Marvin StillmanWilliam TracyMr. and Mrs. Everett L. WessnerAlan N. WhiteFlorence Wisler


CRI Scientific Advisory Council meeting, early 1970s (from left to right): Lloyd J. Old, M.D., Helen Coley Nauts, Edmund Klein, M.D., Robert A. Good, M.D., Ph.D., and Herbert F. Oettgen, M.D.

STEWARDS OF THEORGANIZATIONFor more than 60 years, scientific and philanthropic leaders have steered the Cancer Research Institute with their long-term, significant commitments to the Institute. They support CRI and its mission not only through academic and financial support, but also through astute governance and active participation in the organization’s initiatives.

Board of Trustees

Chairmen

John B. FitzgibbonsChairman and CEOBasin Holdings US LLCNew York, NY

Paul C. ShiverickPartnerSeminole Management Company, Inc.New York, NY

Vice Chairmen

Edgar R. BernerPartnerJohn Lang, Inc.New York, NY

Donald J. GogelChairman and CEOClayton, Dubilier & Rice, LLCNew York, NY

Jacques C. NordemanChairmanNordeman Grimm, Inc.New York, NY

Treasurer

Geoffrey O. ColeyInternational Business HeadMitsubishi UFJ Securities (USA), Inc.New York, NY

Secretary

Thomas G. MendellT.G. Mendell Corp.New York, NY

Members

Peter L. BloomAdvisory DirectorGeneral Atlantic LLCGreenwich, CT

Jennifer L. BrorsenBronxville, NY

James M. CitrinLeader, CEO PracticeSpencer StuartStamford, CT

Sandra Coudert GrahamOyster Bay, NY

Maurice J. CunniffeChairman and CEOVista Capital CorporationGreenwich, CT

W. Robert DahlPrincipalWRD CapitalDarien, CT

Glenn J. DeSimoneGreenwich, CT

Patrick J. DurkinManaging DirectorBarclays CapitalNew York, NY

John E. EckersonFounding Partner and Co-Chief Investment OfficerClaren Road Asset Management, LLCNew York, NY

Sean P. FaheyFounding Partner and Co-Chief Investment OfficerClaren Road Asset Management, LLCNew York, NY

Carlos A. FerrerFounder and Managing MemberFerrer Freeman & Company, LLCGreenwich, CT

Margot E. FreedmanLarchmont, NY

Mitchell H. Gold, M.D.Founder and Managing PartnerAlpine BioVenturesSeattle, WA

Oliver R. Grace Jr.PresidentAssociated Asset Management, Inc.Palm Beach, FL

Michael M. KellenCo-PresidentArnhold and S. Bleichroeder Holdings, Inc.New York, NY

Alexander P. LynchPartnerWhite Deer EnergyNew York, NY

Andrew M. PaulManaging General PartnerEnhanced Equity FundsNew York, NY

Brian RianoCo-Founder and CEOClaren Road Asset Management, LLCNew York, NY

Lief D. RosenblattPartnerENE Investco ManagementNew York, NY

Howard B. SchillerExecutive Vice President and CFOValeant Pharmaceuticals International, Inc.Bridgewater, NJ

Paul J. SekhriSenior Vice PresidentSanofiBridgewater, NJ / Paris, France

Frank V. SicaPartnerTailwind CapitalNew York, NY

James A. SternChairman and FounderThe Cypress GroupNew York, NY



Michael B. TargoffVice Chairman of the BoardLoral Space & CommunicationsNew York, NY

Andrew K. TsaiManaging PrincipalChalkstream Capital Group, L.P.New York, NY

Diane TuftNew York, NY

Heidi UeberrothDirectorPebble Beach CompanyNew York, NY

Lauren S. VeronisNew York, NY

Ronald G. WeinerPresidentPerelson Weiner LLPNew York, NY

James A. WiattCEOCIW ConsultingLos Angeles, CA

Trustees Emeriti

Carter F. BalesChairman and Managing DirectorNewWorld Capital Group, LLCNew York, NY

Howard P. BerkowitzNew York, NY

Donald G. CalderChairmanClear Harbor Asset ManagementNew York, NY

Stuart P. DavidsonManaging DirectorLabrador VenturesMenlo Park, CA

Bruce D. DixonRetired PartnerErnst & YoungGreenwich, CT

Mrs. Charles G. GambrellCharlotte, NC

William O. GrabeAdvisory DirectorGeneral Atlantic LLCNew York, NY

Mrs. Oliver R. GraceNew York, NY

Joyce GreenWesthampton Beach, NY

Ann W. JacksonNew York, NY

Arthur L. JacobsonIndian Wells, CA

Robert A. PosnerManaging DirectorCommonwealth Holding, LPBrookline, MA

Julian RobertsonChairmanTiger Management LLCNew York, NY

Winthrop H. Smith Jr.ChairmanSummit Ventures NE, LLCWarren, VT

Scientific Advisory Council

Director

James P. Allison, Ph.D. 2,3,5,6,7

The University of Texas MD Anderson Cancer Center, Houston, TX

Associate Directors

Glenn Dranoff, M.D. 3,4,6

Dana-Farber Cancer Institute, Boston, MA

Carl F. Nathan, M.D. 2,3,7

Weill Cornell Medical College,New York, NY

Ellen Puré, Ph.D. 7 University of Pennsylvania School of Veterinary Medicine, Philadelphia, PA

Robert D. Schreiber, Ph.D. 2,3,6,7

Washington University School of Medicine, St. Louis, MO

Jedd D. Wolchok, M.D., Ph.D. 4,5,6

Memorial Sloan Kettering Cancer Center and Ludwig Cancer Research,New York, NY

Members

Frederick W. Alt, Ph.D. 2,7

Howard Hughes Medical Institute, Boston Children’s Hospital, and Harvard Medical School, Boston, MA

Richard Axel, M.D. 1,2

Columbia University Medical Center,New York, NY

Nina Bhardwaj, M.D., Ph.D. 6,7 Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY

Harvey Cantor, M.D. 2

Dana-Farber Cancer Institute,Boston, MA

Jonathan S. Cebon, Ph.D., FRACP 4

Austin Health/Ludwig Cancer Research, Melbourne, Australia

Vincenzo Cerundolo, M.D., Ph.D. 3,6

MRC Human Immunology Unit, University of Oxford, Oxford, United Kingdom

Max D. Cooper, M.D. 2

Emory University School of Medicine,Atlanta, GA

Lisa M. Coussens, Ph.D.Oregon Health & Science University,Portland, OR

Peter Cresswell, Ph.D. 2,7

Yale University School of Medicine,New Haven, CT

Charles G. Drake, M.D., Ph.D. 5,6

Johns Hopkins University School of Medicine, The Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD

Michael L. Dustin, Ph.D. 7 NYU Langone Medical Center,New York, NY

Richard A. Flavell, Ph.D., FRS 2

Yale University School of Medicine,New Haven, CT

Thomas F. Gajewski, M.D., Ph.D. 6 University of Chicago,Chicago, IL

Laurie H. Glimcher, M.D. 2

Weill Cornell Medical College,New York, NY

Philip D. Greenberg, M.D. 3,7

University of Washington School of Medicine and Fred Hutchinson Cancer Research Center, Seattle, WA

Axel Hoos, M.D., Ph.D. 5

GlaxoSmithKline, Collegeville, PA

Patrick Hwu, M.D. 5

The University of Texas MD Anderson Cancer Center, Houston, TX

Elizabeth M. Jaffee, M.D. 4,5,6


Carl H. June, M.D. 4

Abramson Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA

Michael Kalos, Ph.D. 5

Eli Lilly & Company, New York, NY

Michael Karin, Ph.D. 2

University of California, San Diego,La Jolla, CA

John M. Kirkwood, M.D. 6

University of Pittsburgh Cancer Institute, Pittsburgh, PA

George Klein, M.D., D.Sc. 2,3

Karolinska Institute, Stockholm, Sweden

Alexander Knuth, M.D. 3,4,6

National Center for Cancer Care and Research, Hamad Medical Corporation, Doha, Qatar

Lewis L. Lanier, Ph.D. 2,7

University of California, San Francisco,San Francisco, CA

Hyam I. Levitsky, M.D. 5

Roche Glycart AG, Schlieren, Switzerland, and Johns Hopkins University School of Medicine,Baltimore, MD

Dan R. Littman, M.D., Ph.D. 2,7

NYU Langone Medical Center,New York, NY

Nils Lonberg, Ph.D. 5

Bristol-Myers Squibb, Milpitas, CA

Tak W. Mak, Ph.D., D.Sc., F.R.S.C. 2,7

The Campbell Family Institute for Breast Cancer Research at Princess Margaret Hospital, University Health Network, University of Toronto,Toronto, Canada

Philippa C. Marrack, Ph.D. 2

National Jewish Health and the University of Colorado, Denver, Denver, CO

Cornelis J.M. Melief, M.D., Ph.D. 3,6

Leiden University Medical Center,Leiden, The Netherlands

Ira Mellman, Ph.D. 2,5

Genentech, South San Francisco, CA

Malcolm A.S. Moore, D.Phil.Memorial Sloan Kettering Cancer Center, New York, NY

Lee Nadler, M.D.Dana-Farber Cancer Institute,Boston, MA

Kunle Odunsi, M.D., Ph.D. 4,5,6

Roswell Park Cancer Institute,Buffalo, NY

Drew M. Pardoll, M.D., Ph.D. 3,7


William E. Paul, M.D. 2

National Institute of Allergy and Infectious Diseases, NIH,Bethesda, MD

Klaus Rajewsky, M.D. 2,3

Max-Delbrück Center for Molecular Medicine, Berlin, Germany

Anjana Rao, Ph.D. 2,7

La Jolla Institute for Allergy and Immunology, Sanford Consortium for Regenerative Medicine, La Jolla, CA

Jeffrey V. Ravetch, M.D., Ph.D. 2

The Rockefeller University,New York, NY

Stanley R. Riddell, M.D. 6

Fred Hutchinson Cancer Research Center, Seattle, WA

Alexander Y. Rudensky, Ph.D. 2,7

Memorial Sloan Kettering Cancer Center, New York, NY

Bijan Safai, M.D., D.Sc.New York Medical College,Valhalla, NY

Shimon Sakaguchi, M.D., Ph.D. 2,3

Immunology Frontier Research Center, Osaka University, Osaka, Japan

Lawrence E. Samelson, M.D. 7 National Cancer Institute, NIH,Bethesda, MD

Hans Schreiber, M.D., D.MSc., Ph.D. 3,7

University of Chicago, Chicago, IL

Ton N. Schumacher, Ph.D.The Netherlands Cancer Institute, Amsterdam, and Leiden University, Leiden, The Netherlands

Craig L. Slingluff Jr., M.D. 4

University of Virginia School of Medicine, Charlottesville, VA

Mark J. Smyth, Ph.D.QIMR Berghofer Medical Research Institute, Queensland, Australia

Pramod K. Srivastava, M.D., Ph.D. 3,5,6

University of Connecticut Health Center, Farmington, CT

Susumu Tonegawa, Ph.D. 1,2

Massachusetts Institute of Technology, Cambridge, MA

Giorgio Trinchieri, M.D. 3,6,7

National Cancer Institute, NIH,Frederick, MD

Emil R. Unanue, M.D. 2

Washington University School of Medicine, St. Louis, MO

Ulrich H. von Andrian, M.D., Ph.D. 7 Harvard Medical School and Boston Children’s Hospital, Boston, MA, and The Ragon Institute of Massachusetts General Hospital, MIT, and Harvard University, Cambridge, MA

Robert H. Vonderheide, M.D., D.Phil. 6

Abramson Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA

Hao Wu, Ph.D. 7 Boston Children’s Hospital and Harvard Medical School, Boston, MA

Cassian Yee, M.D. 7 The University of Texas MD Anderson Cancer Center, Houston, TX

Rolf M. Zinkernagel, M.D., Ph.D. 1,2,3

University of Zürich, Zürich, Switzerland

1 Nobel Laureate2 Member, National Academy of Sciences3 Member, Academy of Cancer Immunology4 Clinical Accelerator Scientific Advisory Committee5 Cancer Immunotherapy Consortium Leadership Committee6 CLIP Review Committee7 Postdoctoral Fellowship Review Committee

CVC Trials Network

Director and Scientific Advisory Committee Chair

Jedd D. Wolchok, M.D., Ph.D.Memorial Sloan Kettering Cancer Center and Ludwig Cancer Research,New York, NY

Scientific Advisory Committee

Timothy A. Chan, M.D., Ph.D.Memorial Sloan Kettering Cancer Center, New York, NY

Jonathan S. Cebon, Ph.D., FRACPAustin Health/Ludwig Cancer Research, Melbourne, Australia

George Coukos, M.D., Ph.D.University Hospital of Lausanne,Lausanne, Switzerland

Glenn Dranoff, M.D.Dana-Farber Cancer Institute,Boston, MA

Lawrence Fong, M.D.University of California, San Francisco,San Francisco, CA

Elizabeth M. Jaffee, M.D.Johns Hopkins University School of Medicine, Baltimore, MD

Carl H. June, M.D.Abramson Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA

Alexander Knuth, M.D.National Center for Cancer Care and Research, Hamad Medical Corporation, Doha, Qatar

Kunle Odunsi, M.D., Ph.D.Roswell Park Cancer Institute,Buffalo, NY

Antoni Ribas, M.D., Ph.D.UCLA Medical Center, Los Angeles, CA

Michel Sadelain, M.D., Ph.D.Memorial Sloan Kettering Cancer Center, New York, NY

Neil H. Segal, M.D., Ph.D.Memorial Sloan Kettering Cancer Center, New York, NY

Andrew G. Sikora, M.D., Ph.D.Baylor College of Medicine,Houston, TX

Craig L. Slingluff Jr., M.D.University of Virginia Cancer Center,Charlottesville, VA

Finance, Intellectual Property, Clinical Trials Management, and Administration

Cancer Research InstituteLynne A. HarmerAdam KolomVanessa Lucey, Ph.D., MBAJill O’Donnell-Tormey, Ph.D.

Ludwig Cancer ResearchPär Olsson, Ph.D. Linda Pan, Pharm.D.Aileen Ryan Jonathan Skipper, Ph.D.Ralph Venhaus, M.D.

Global Clinician and Scientist Membership

United States• James P. Allison, Ph.D., The

University of Texas MD Anderson Cancer Center

• Nina Bhardwaj, M.D., Ph.D., Icahn School of Medicine at Mount Sinai

• Timothy A. Chan, M.D., Ph.D., Memorial Sloan Kettering Cancer Center

• Hearn Jay Cho, M.D., Ph.D., Icahn School of Medicine at Mount Sinai

• Glenn Dranoff, M.D., Dana-Farber Cancer Institute

• Gavin P. Dunn, M.D., Ph.D., Washington University

• Lawrence Fong, M.D., University of California, San Francisco

• Leena Gandhi, M.D., Ph.D., Dana-Farber Cancer Institute

• Sacha Gnjatic, Ph.D., Icahn School of Medicine at Mount Sinai

• Philip D. Greenberg, M.D., University of Washington, Fred Hutchinson Cancer Research Center

• F. Stephen Hodi Jr., M.D., Dana-Farber Cancer Institute, Harvard Medical School

• Elizabeth M. Jaffee, M.D., Johns Hopkins University School of Medicine

• Carl H. June, M.D., Perelman School of Medicine, University of Pennsylvania

• Achim Jungbluth, M.D., Memorial Sloan Kettering Cancer Center

• Thomas J. Kaley, M.D., Memorial Sloan Kettering Cancer Center

• John M. Kirkwood, M.D., University of Pittsburgh Cancer Institute

• Alexander M. Lesokhin, M.D., Memorial Sloan Kettering Cancer Center

• Kunle Odunsi, M.D., Ph.D., Roswell Park Cancer Institute

• Hideho Okada, M.D., Ph.D., University of California, San Francisco

• Drew M. Pardoll, M.D., Ph.D., Johns Hopkins University School of Medicine

• Marshall R. Posner, M.D., Icahn School of Medicine at Mount Sinai

• David Reardon, M.D., Dana-Farber Cancer Institute

• Antoni Ribas, M.D., Ph.D., UCLA Medical Center

• Michel Sadelain, M.D., Ph.D., Memorial Sloan Kettering Cancer Center

• Yvonne Saenger, M.D., Icahn School of Medicine at Mount Sinai

• Neil H. Segal, M.D., Ph.D., Memorial Sloan Kettering Cancer Center

• Padmanee Sharma, M.D., Ph.D., The University of Texas MD Anderson Cancer Center

• Andrew G. Sikora, M.D., Ph.D., Baylor College of Medicine

• Craig L. Slingluff Jr., M.D., University of Virginia Cancer Center

• Mario Sznol, M.D., Yale Cancer Center

• Suzanne L. Topalian, M.D., Johns Hopkins University School of Medicine

• Ralph R. Weichselbaum, M.D., University of Chicago

• Jedd D. Wolchok, M.D., Ph.D., Memorial Sloan Kettering Cancer Center, Ludwig Cancer Research

• Cassian Yee, M.D., The University of Texas MD Anderson Cancer Center

• Hassane M. Zarour, M.D., University of Pittsburgh Cancer Institute

Europe• Maha Ayyoub, Ph.D., Centre de

Lutte Contre Le Cancer Nantes-Atlantique, France

• Luigi Buonaguro, M.D., National Cancer Institute Pascale, Italy

• Vincenzo Cerundolo, M.D., Ph.D., University of Oxford, United Kingdom

• George Coukos, M.D., Ph.D., University Hospital of Lausanne, Switzerland

• Dirk Jäger, M.D., National Center for Tumor Diseases, University Clinic of Heidelberg, Germany

• Elke Jäger, M.D., Krankenhaus Nordwest, Germany

• Judith Kroep, M.D., Ph.D., Leiden University Medical Center, The Netherlands

• Simon A. Laban, M.D., University of Ulm, Germany

• Cornelis J.M. Melief, M.D., Ph.D., Leiden University Medical Center, The Netherlands

• Pedro J. Romero, M.D., University Hospital of Lausanne, Switzerland

• Daniel E. Speiser, M.D., University Hospital of Lausanne, Switzerland

• Danila Valmori, Ph.D., Centre de Lutte Contre Le Cancer Nantes-Atlantique, France

• Nicolas Van Baren, M.D., Ph.D., Ludwig Cancer Research, Belgium

• Maries van den Broek, Ph.D., University of Zürich, Switzerland

• Benoît J. Van den Eynde, M.D., Ph.D., Ludwig Cancer Research, Belgium

• Pierre van der Bruggen, Ph.D., Ludwig Cancer Research, Belgium

• Sjoerd Henricus van der Burg, Ph.D., Leiden University Medical Center, The Netherlands

• Alfred Zippelius, M.D., University of Basel, Switzerland

Asia• Shinichi Kageyama, M.D., Mie

University School of Medicine, Japan

• Alexander Knuth, M.D., National Center for Cancer Care and Research, Qatar

• Eiichi Nakayama, M.D., Ph.D., Kawasaki University of Medical Welfare, Japan

• Hiroyoshi Nishikawa, M.D., Ph.D., Osaka University, Japan

• Hiroshi Shiku, M.D., Mie University School of Medicine, Japan

• Hisashi Wada, M.D., Ph.D., Osaka University, Japan

Australia• Jonathan S. Cebon, Ph.D., FRACP,

Austin Health/Ludwig Cancer Research

• Mark J. Smyth, Ph.D., QIMR Berghofer Medical Research Institute

Cancer Immunotherapy Consortium

Co-Directors

James P. Allison, Ph.D.The University of Texas MD Anderson Cancer Center, Houston, TX

Axel Hoos, M.D., Ph.D.GlaxoSmithKline, Collegeville, PA

Leadership Committee Members

Charles G. Drake, M.D., Ph.D.Johns Hopkins University School of Medicine, Baltimore, MD

Patrick Hwu, M.D.The University of Texas MD Anderson Cancer Center, Houston, TX

Elizabeth M. Jaffee, M.D.Johns Hopkins University School of Medicine, Baltimore, MD

Michael Kalos, Ph.D.Eli Lilly & Company, New York, NY

Hyam I. Levitsky, M.D.Roche Glycart AG, Schlieren, Switzerland, and Johns Hopkins University School of Medicine,Baltimore, MD

Nils Lonberg, Ph.D.Bristol-Myers Squibb, Milpitas, CA

Ira Mellman, Ph.D.Genentech, South San Francisco, CA

Kunle Odunsi, M.D., Ph.D.Roswell Park Cancer Institute, Buffalo, NY

Pramod K. Srivastava, M.D., Ph.D. University of Connecticut School of Medicine, Farmington, CT

Jedd D. Wolchok, M.D., Ph.D. Memorial Sloan Kettering Cancer Center and Ludwig Cancer Research,New York, NY

Cancer Immunotherapy Consortium Co-Director Axel Hoos, M.D., Ph.D., of GlaxoSmithKline

Young Philanthropists Council

Chair

Samantha KnapikOn Deck Capital New York, NY

Vice Chair

Emily SlaterCantor Fitzgerald/BGC Partners New York, NY

Secretary

Priyanka SewhaniJP MorganNew York, NY

Treasurer

Eric AdamsJP Morgan New York, NY

Members

Megan Bannigan Debevoise & Plimpton New York, NY

Robin BeltraniGlobeTax Services, Inc. New York, NY

George BergamoCentauri Investment ManagementNew York, NY

Anne BracegirdleChristie’sNew York, NY

Christina BrownHealthFirstNew York, NY

Emily CraftThe Peter and Carmen Lucia Buck Foundation, Inc. New York, NY

CRI Staff

Senior Staff

Jill O’Donnell-Tormey, Ph.D.CEO and Director of Scientific Affairs

Brian M. BrewerDirector of Marketing and Communications

Lynne A. HarmerDirector of Grants Administration and Special Events

Alfred R. MassidasCFO and Director of Human Resources

Sharon SladeDirector of Strategic Initiatives

Staff

Hannah BelisleDevelopment Associate

Emily HelckOnline Community Manager

Rupinder KaurDatabase Administrator

Erin KimEvents Coordinator

Michelle LiewDigital Media Manager

Emily LivingstoneDevelopment Associate

Vanessa Lucey, Ph.D., MBASenior Research Analyst

Alexandra MulveyAssociate Director of Communications

Shasell NegronOffice Manager / Workplace Giving Campaign Manager

Kasturi “Devi” SharmaDonations Processing Manager

Marla SincavageManager, Corporate and Foundation Giving

Matthew TontonozScience Writer

Denise UptonGrants Administrator

Jasmine WrightAssistant to the CEO

Qing Hua ZhangAssistant Controller

Consultant

Adam KolomManaging Director, Clinical Accelerator

Coley to CureRead more about CRI’s pioneering role in developing cancer immunotherapy over the past six decades at www.bit.ly/CRIretrospective.


Kate CuccoNew York State AssemblyNew York, NY

Alexis HoveyRalph Lauren New York, NY

Marissa KaplanConMed Corporation New York, NY

Sean KielyThe New York Retail ReportNew York, NY

Mark KochAT&T Global Broadcast ServicesNew York, NY

Sharon MinickSiriusXM Radio Hoboken, NJ

Nicole NegrinRalph Lauren Corporation New York, NY

Kristen RathfelderOch Ziff Capital Management New York, NY

Josephine VellaUnited States Attorney’s Office, EDNYBrooklyn, NY

Kendall WrigleyVitech Systems Group New York, NY

Young Philanthropists Council members Alexis Feldman, Emily Slater, Samantha Knapik, Kate Cucco, and Sean Kiely

GIVING TO THE

The Cancer Research Institute (CRI) has a long tradition of responsible stewardship of donor funds. We receive the highest marks from charity watchdog groups, including an “A” grade from the American Institute of Philanthropy and a four-star rating from Charity Navigator. CRI also meets all 20 standards of the Better Business Bureau Wise Giving Alliance. Donors to CRI can be confident that their donation, in any amount, will do the most good possible. To help you make the most fitting and fulfilling contribution to CRI, please contact our Development Office at (212) 688-7515 or send an email to [email protected].

OUTRIGHT GIFTS

Cash Donations by check or credit card may be sent directly to CRI or processed through our secure website at www.bit.ly/CRIdonate.

Property other than cash Donating securities, automobiles, and similar properties can often be a tax-efficient method for making a meaningful gift to CRI.

Workplace giving programs Ask your human resources department if your company has a plan through which you can contribute to CRI.

Matching gifts Contact your human resources department to inquire if your employer matches contributions or browse our online matching gift database to see if your company is listed at www.bit.ly/CRImatch.

PLANNED GIFTS

Planned gifts include bequests made through a living trust or inclusion of the Cancer Research Institute in your will as a beneficiary of cash, securities, or personal property. Your bequest should include the Institute’s federal tax ID number (13-1837442) and a statement such as the following:

“I bequeath to the Cancer Research Institute, a not-for-profit corporation of the State of New York, having its principal office at One Exchange Plaza, 55 Broadway, Suite 1802, New York, New York 10006, the sum of $_____ for its general operating purposes.”

You should, of course, always consult your attorney and tax advisor for the formal writing of your will and to discuss the tax implications of any form of planned giving.

COMMUNITY FUNDRAISING

Want to hold a bake sale to raise money for cancer research? How about a fashion show, dinner, or a music concert? Maybe you’re getting married and would prefer guests give to charity. We offer support for these and other fundraising ideas. Visit our website at www.bit.ly/CRIfundraise to learn more about how you can organize your own special event.

FOR CORPORATE FRIENDS

No one organization, company, or group can solve the cancer problem alone. It takes collaboration to change the course of cancer. CRI welcomes opportunities to work together with others to develop research, educational, and awareness-building programs designed to advance cancer immunotherapy. Contact Sharon Slade at [email protected] or (212) 688-7515 x230 to learn more.

CANCER RESEARCH INSTITUTE


Since 1953, the Cancer Research Institute has invested $282 million to fund nearly 3,000 scientists all over the world.

Sarah Trifari, Ph.D., CRI postdoctoral fellow at La Jolla Institute for Allergy and Immunology

NATIONAL HEADQUARTERS

One Exchange Plaza55 Broadway, Suite 1802 New York, NY 10006Tel. (212) 688-7515Toll-Free (800) 99-CANCERFax (212) 832-9376Email [email protected]

VOLUNTEER OFFICES

344 Hauser Boulevard, Unit 422Los Angeles, CA 90036Tel. (323) 935-2520

101 University Avenue, 4th FloorPalo Alto, CA 94301Tel. (650) 365-6441

80 Field Point RoadGreenwich, CT 06830Tel. (203) 622-0522

184 Fisher AvenueBrookline, MA 02445Tel. (617) 566-0100

6000 Uptown Boulevard, Suite 309Albuquerque, NM 87110Tel. (505) 234-6255

2802 Flintrock Trace, Suite 220Austin, TX 78738Tel. (512) 610-5530

122 River Run RoadLancaster, VA 22503Tel. (703) 759-0835

www.cancerresearch.org

2014 annual report - advancing immunotherapy research

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