Fast Forward2010 Annual Report

Welcome to The Children’s Hospital of Philadelphia 2010 – 11 Annual Report. If the printed edition of the Report looks

a bit different from those of years past,

there’s good reason: This year, for the first time, the Annual Report was

designed as an online publication. We’ve made just a limited run of

printed copies.

Fittingly, our theme this year is Fast Forward. It speaks of course to the

dynamic new electronic format, but much more importantly, to the

spirit of our work here at CHOP.

“The next breakthrough, the next cure cannot come quickly enough.”

Our all-consuming mission is to fast forward exceptional healthcare for

children — whether that’s rapidly translating scientific discovery into

promising new treatments (see “Open for Brilliance,” Page 20), providing

the most advanced, forward-looking therapies (“Years Ahead,” Page 2

and “Look at Us Now,” Page 6), creating innovative new programs that

anticipate and address significant pediatric health issues (“This Time,

Hope,” Page 14 and “All the Right Moves,” Page 44), or creating the

safest environment for our patients (“Practice Makes Perfect,” Page 36

and “Do No Harm,” Page 32). Because we work with children, we all

feel the urgency to make progress — the next breakthrough, the next

cure cannot come quickly enough.

I’d like to provide a special recognition to our donor community. Your

support is the engine that fuels our incredible staff ’s visionary ideas

and helps us fast-forward them into real-life solutions. We cannot say

it enough: thank you for your unwavering generosity and for traveling

with us on the journey to improve pediatric healthcare.

Now, I invite you to fast forward into the pages of our Annual Report.

I also hope you will go online to see the full content, including

additional photographs, video and audio features at www.chop.edu/ar.

And please, let me know what you think of the new format!

Steven M. Altschuler, M.D.

Chief Executive Officer

Table of Contents

Cancer Care 2 Years Ahead: An advanced form of radiation treatment gives Cancer Center patients hope for a better future.

Fetal Therapy 6Look at Us Now: The Center for Fetal Diagnosis and Treatment celebrates 15 years of better beginnings for thousands of children and their families.

Cardiac Care 14 This Time, Hope: A rare cardiac diagnosis that devastated a family decades ago has a much brighter outcome today.

Research 20 Open for Brilliance: The world’s best and brightest pediatric researchers have a stunning — and intelligent — new home.

Craniofacial Surgery 26 Portrait Perfect: A unique program uses portrait painting to help craniofacial patients see themselves in a new light.

Transition to Adult Care 28Independence Ahead: How Children’s Hospital prepares patients to take charge of their health as they move toward adulthood.

Patient Safety 32 Do No Harm: To keep the children in our care safe, every employee has a responsibility — and a voice.

Simulation Training 36Practice Makes Perfect: Preparing new and veteran clinicians for the unexpected, using some very special “patients.”

Nursing Advocacy 44All the Right Moves: Innovative fellowships help nurses grow professionally and give back to the local community.

Philanthropy 48 Good Times, Great Cause: Highlights of an event-packed year

People 58 18 Ways To Be Extraordinary

Dedication to Richard M. Armstrong Jr.

Numbers 66Financial SummaryBalance SheetHospital Statistics

About CHOP 70ManagementBoard of TrusteesExecutive Council of Volunteer OrganizationsEndowed ChairsCredits

Years Ahead

Look at Us Now

This Time, Hope

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6

14

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Ryan, 2, is thriving after receiving proton radiation therapy, an advanced treatment now available through CHOP’s Cancer Center.

Years AheadAdvanced radiation treatment gives Cancer Center patients hope for a better future

It all happened so unbelievably fast.

On the Friday before Memorial Day 2010, Trish Cartafalsa noticed that her 2-year-old son, Ryan, was having trouble with his balance. Less than a week later, he was having a brain tumor removed at The Children’s Hospital of Philadelphia.

Like many children with brain tumors, Ryan needed radiation treatment in addition to surgery. His oncologist, Jean B. Belasco, M.D., explained to Trish and her husband, Ben, that Ryan was a good candidate for proton therapy, an advanced form of radiation that had just become available through CHOP’s Cancer Center. u

Cancer Care

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CHOP proton patients receive their treatment at Penn Medicine’s Roberts Proton Therapy Center, the first proton facility in the mid-Atlantic region.

Cancer Care

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A 220-ton particle accelerator (cyclotron) delivers a high-energy beam of proton radiation to each of the Roberts Center’s treatment rooms, where it kills cancer cells with extraordinary precision.

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These scans show the difference between proton therapy (left) and conventional radiation (right), using color to indicate areas that will be affected by radiation. Proton therapy targets radiation at the tumor site (outlined in pink) with extreme precision while minimizing damage to surrounding areas, which results in fewer side effects.

Proton therapy is much more precise than conventional radiation, which can cause short-term side effects like nausea and fatigue as well as longer-term complications like learning difficulties and growth problems. All of these side effects can be especially pronounced in young brain tumor patients, whose cancers often require an extremely high dose of radiation — and whose age makes them more susceptible to radiation’s harmful effects.

In fact, for some survivors of childhood brain tumors who receive conventional radiation, “the intellectual impact can be dramatic, affecting

all aspects of day-to-day life,” says John M. Maris, M.D., chief of the Division of Oncology. With the advent of proton therapy, he adds, “we are very optimistic that major side effects will be substantially reduced and, in some cases, even eliminated.”

So far, Ryan’s 33 proton therapy treatments haven’t slowed him down one bit. “He did really well,” says Trish, who kept track of his side effects as part of a research study CHOP is leading. “I felt like every day I was circling, ‘He was normal.’” n

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In 1995, during a routine prenatal ultrasound, Felicia and Roberto Rodriguez received terrible news. The child Felicia was carrying had a huge growth in one lung — a rare, life-threatening condition. Their physician told them they had three options: Abort the pregnancy. Let the fetus die on its own. Or try to save the baby through fetal surgery, an innovative form of therapy available at The Children’s Hospital of Philadelphia.

Determined to do everything possible to save their unborn child, the Rodriguezes traveled from their West Palm Beach, Fla., home to CHOP’s newly opened Center for Fetal Diagnosis and Treatment, one of the few programs worldwide capable of treating birth defects in utero. After an extensive

Look at Us NowA remarkable program — and its first patient — turn 15

evaluation and counseling about the risks of fetal surgery, N. Scott Adzick, M.D., M.M.M., the center’s director and a pioneer in the field of fetal surgery, opened Felicia’s uterus, removed the lesion that occupied a large portion of the fetus’ left lung, then closed the womb to allow the pregnancy to continue to near-term gestation. It was the first-ever fetal surgery at CHOP — and a resounding success. Thirteen weeks later, Roberto Rodriguez Jr. was born with a healthy set of lungs and nothing more than a scar to show for his revolutionary surgery.

“I see that scar every day when I wake up, and I’m grateful,” says Roberto Jr., now a freshman in high school with dreams of becoming a professional baseball player. u

Fetal Therapy

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Lifesaving intervention — Roberto Rodriguez Jr.’s lung lesion surgery in 1995 was the first-ever fetal surgery at CHOP.

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Roberto Jr., 15, showing off his baseball trophies. He hopes to take his love of baseball to the big leagues.

Fetal Therapy

“Only 25 years ago, the concept of treating the fetus as a patient in its own right was considered a radical, futuristic idea — even in some very sophisticated scientific circles,” Adzick says. “Today, the landscape is dramatically different.”

2010 marked the center’s 15th anniversary. Like Roberto, it has grown in incredible ways, helping to establish fetal therapy as one of the most promising fields in medicine today, advancing groundbreaking treatments and offering a level of comprehensive care that simply doesn’t exist elsewhere for the full spectrum of birth defects.

The Rodriguezes were among the first of more than 11,000 families from all 50 states and more than 50 countries, facing the impact of a prenatally diagnosed birth defect, to look to the center as a beacon of hope and help. They have seen the program’s growth firsthand at the annual Fetal Family Reunion, where attendance has swelled from fewer than 10 families in 1997 to more than 700 people this past year.

“It’s phenomenal to see,” Felicia says. “Now you can barely fit everybody in one photo frame.” u

Growing Together

Felicia and Roberto Jr., seated far right, in the Center for Fetal Diagnosis and Treatment’s first family reunion group photo.

2010

1997

The Fetal Family Reunion in 2010 brought more than 700 people together for a fun, inspiring day.

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Fetal Therapy

In 2008, Roberto Jr. and his family participated in another major milestone at the center, cutting the “umbilical cord” ribbon at the grand opening of the Lynne and William Garbose Family Special Delivery Unit, the world’s first comprehensive birth facility for mothers carrying fetuses with known birth defects. Since then, more than 600 mothers have delivered in the unit.

“It’s an exhilarating feeling to know that you’ve been a part of something so great,” Felicia says. “Every day we’re reminded of the miracle we were given.” u

(At right) Felicia and Roberto Rodriguez Jr., center, helping to cut the “umbilical cord” ribbon, along with Lynne and Bill Garbose, far left, at the opening of the Garbose Family Special Delivery Unit, the world’s first labor/delivery unit exclusively for mothers of babies with birth defects.

A Special Place

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Roberto Jr., with parents Roberto Sr. and Felicia Rodriguez, at the opening of the Special Delivery Unit.

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Fetal Therapy — Spina Bifida

The Center for Fetal Diagnosis and Treatment was recently at the forefront of one of the most exciting developments in the history of treatment for birth defects. In 2010, a groundbreaking national study, published in the New England Journal of Medicine, proved that surgical repair before birth could prevent or lessen some of the most devastating effects of spina bifida, the most common central nervous system birth defect.

Fetal surgeons at the center developed the prenatal repair procedure for spina bifida and the center team has the greatest collective experience in the world in applying this complex and immensely promising therapy.

“For years, spina bifida has been a problem you deal with after birth. You get what you get, and you make the best of it,” says Lori J. Howell, R.N., M.S., the center’s executive director. “Now with fetal surgery, you’re able to look at it in a positive light. That is amazing, and it’s really due to our clinical team’s efforts.” n

Learn about fetal surgery for spina bifida at fetalsurgery.chop.edu/spinabifida.

UPDAT

E

2011BIRTH OF A BREAKTHROUGH

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In 2000, Sean Mulligan was diagnosed with spina bifida in utero, and became one of the first CHOP patients to undergo prenatal repair of the birth defect. Today, Sean is 10 — and look at him now!

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Cardiac Care

It felt as if lightning had struck twice. Jack Rychik, M.D., director of the Fetal Heart Program at The Children’s Hospital of Philadelphia, looked at the ultrasound image and gave expectant parents Tara and Adam devastating news: Their unborn baby’s heart had only three functioning chambers, instead of the normal four.

Tara immediately understood the gravity of the diagnosis. Twenty-eight years before, her little sister, Erin, had been born with the same extremely rare heart defect: double inlet left ventricle. Despite medicine’s best efforts at the time, she died at the age of 3.

Though she now feared for her own child, Tara soon realized how much had changed in the decades since her sister’s death. For one thing, her baby, still in the womb, was already a patient of the renowned Cardiac Center at Children’s Hospital.

This Time, HopeAfter receiving the same rare diagnosis that ended in tragedy decades before, a family finds hope in a new era of cardiac care

Beyond Survival Babies born with complex heart defects once faced dismal odds. Today, thanks to CHOP and other institutions that have pioneered advances in surgical repair, catheterization techniques and treatment strategies, most survive. In fact, more than half a million children with congenital heart disease in the United States are now growing toward adulthood.

But survival is only the first step. As these children age — the oldest are in their 20s and 30s — doctors have begun to realize that many are experiencing complications later in life, such as learning and developmental disabilities, growth delays, and lung and liver disease. The next great challenge for clinicians and researchers is to understand why these late effects occur and how they can be mitigated or even prevented. u

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Abby was a patient of the Cardiac Center at CHOP before she was born and will remain one for many years. Here the goal is to ensure that children with complex heart defects not only survive, but also thrive.

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AbigailTara gave birth to Abigail Brigid Heinze in Children’s Hospital’s Garbose Family Special Delivery Unit. In her first two years of life, this determined little girl has undergone two open-heart surgeries, and will soon have a third. She has been cared for by some of the world’s leading pediatric cardiac clinicians. But one of the most innovative aspects of her care is just beginning.

Abby is among the first patients to enroll in CHOP’s NeuroCardiac Care Program (NCCP), created to follow children with complex congenital heart defects from infancy onward.The program brings together specialists from multiple disciplines to screen for issues such as learning disabilities, motor-skill delays and other developmental problems that are more common among survivors.

Because some of the services it provides aren’t covered by insurance, the NCCP is one of the innovative programs at CHOP that relies partially on philanthropy. Not only will current patients reap the benefits of such focused attention, research conducted by the NeuroCardiac Research Group, led by J. William Gaynor, M.D., a cardiothoracic surgeon at CHOP, will provide invaluable new knowledge and help improve school performance and other long-term

neurodevelopmental outcomes for future patients. The NCCP is led by Gil Wernovsky, M.D., medical director, and Jean M. Carroll, R.N., M.S.N., program manager.

“When our patients experience problems, such as difficulty in school,” says Wernovsky, “those are our problems, too. We want to empower families to best manage their children’s care and ensure they thrive.”

Abby will also have the opportunity to be part of CHOP’s new Single Ventricle Survivorship Program, an interdisciplinary effort focused specifically on the unique medical needs of children whose hearts have just one ventricle. Led by Rychik, the program will enroll patients from across the nation. As with the NCCP, there will be a constant and reciprocal flow of knowledge from research lab to clinic — today’s patients both benefiting from and contributing to the development of ever-improving treatment strategies.

As Rychik observes: “In one generation, a baby succumbs. In the next, a baby survives, but with a new set of challenges, many of which are unexpected. While we are optimistic, the future is uncertain. Our efforts must continue to be focused on finding solutions to these new challenges, in order to help today’s survivors as well as generations yet to come.” u

Cardiac Care

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Abby with her cardiologist, Gil Wernovsky, M.D. Thirty years ago, as a pediatric resident in New York, Wernovsky helped care for Abby’s aunt Erin. Today, he and his team can offer Abby a much brighter outlook.

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Full CircleFor Abby’s family, her remarkable progress brings some resolution to the tragedy they faced many years ago. Her grandmother, Carol, still grieves the daughter she lost, but rejoices in hope for Abby’s long life.

“Watching Abby thrive is happiness,” she says. “It makes me so proud that we’ve come this far — to have been a part of it, to know that Erin’s life wasn’t in vain.” n

Cardiac Care

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Abby’s family (from left, parents Tara and Adam and grandmother Carol) take joy in every trip to the park — and every moment — with her. They rejoice in hope for her long life.

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At The Children’s Hospital of Philadelphia, there is no word like cure.

The Ruth and Tristram Colket, Jr. Translational Research Building, opened in the spring of 2010, is filling with elite research teams devoted to translating laboratory findings to treatments. The 11-story building was made possible by a gift from Ruth and Tristram Colket, Jr., longtime philanthropists devoted to the Hospital’s mission.

The building stands near the Main Hospital. Patients and families can take comfort knowing that a short distance away, brilliant minds are focused on the cures they need.

See what’s going on inside. u

Open for BrillianceNew building houses the world’s best and brightest researchers

Research

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The recently opened 450,000-square-foot Colket Building is not only the heart of CHOP’s research efforts, it is also the Hospital’s first “green” building.

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Directed by John M. Maris, M.D., the Center for Childhood Cancer Research brings together a multidisciplinary team of researchers focused on finding new treatments for all types of childhood cancer. In just the past few years, the team has made remarkable strides in defining the genetics of neuroblastoma; some of this work led very quickly to a clinical trial of a new, targeted treatment. Other current research focuses on immunotherapy, which uses the body’s own immune system to destroy cancer cells. u

Floors 3 & 4: Center for Childhood Cancer Research

A team fights deadly childhood cancers

Research

Investigators in CHOP’s Center for Childhood Cancer Research are advancing the search for a cure for patients like Charlie, 3, who was diagnosed with neuroblastoma in December 2009.

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Directed by Katherine A. High, M.D., the Center for Cellular and Molecular Therapeutics is working to discover new gene and cell therapies for hemophilia and other genetic disorders. The team, along with researchers from the University of Pennsylvania School of Medicine, has been recognized internationally for an ongoing study of gene therapy for a rare form of inherited blindness. All 12 of the children and adults who received the treatment showed improvement in sight. The improvement was particularly pronounced in the children: Some who were legally blind are now able to play sports, read without Braille and even ride bicycles. u

Floor 5: Center for Cellular and Molecular Therapeutics

A team works toward a cure for a rare form of blindness

Yannick Duwe, of Belgium, read with Braille before a revolutionary treatment at CHOP. Now he is able to ride a bike and throw a ball with his dad.

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When Douglas C. Wallace, Ph.D., and 18 of his colleagues moved into the Colket Translational Research Building this summer to establish the Center for Mitochondrial and Epigenomic Medicine (CMEM), they brought with them an entirely new way of looking at disease — one that bridges divides and transcends disciplines.

Wallace and his team believe that many diseases that affect babies share a common underlying cause with diseases associated with aging and the elderly. They see striking similarities between diseases that damage the eye and those that harm the heart, and between the causes of Alzheimer’s and autism, Down syndrome and dementia. “You might think those are totally different,” says Wallace. “We think they’re the same.”

It all comes down to an idea that Wallace has spent much of the last 40 years exploring: that an understanding of how the body makes and uses energy is the key to understanding many complex diseases.

Ninety percent of the body’s energy is produced by tiny structures in the cell called the mitochondria. Wallace, a pioneer in the field of human mitochondrial genetics, believes that mitochondrial dysfunction is the root cause of many diseases, from epilepsy to obesity. If the mitochondria don’t work correctly, your tissues with the highest energy demands — including your brain, heart,

Internationally renowned scientist brings his research program to CHOP

Floor 6: Center for Mitochondrial and Epigenomic Medicine

muscles, kidneys and endocrine system — are the first to be affected. With insufficient energy, they cannot do their work — a scenario Wallace compares to a metropolitan brownout.

Wallace applies the same logic to a host of conditions that are usually thought of as very different from one another. “The difference between the age-related disease of the old person and the acute disease of the baby in the neonatal intensive care unit is that the baby has a severe energy deficiency, whereas the old person has a milder, chronic problem that gets exacerbated by the age-related decline in energy production that lies at the root of the aging process,” he says. “The severity and the age of onset is a matter of degree.”

In their sixth-floor laboratory in the Colket Translational Research Building, Wallace and his team are already developing model systems and treatments through which they hope to develop procedures to repair mitochondrial problems — therapies that might be beneficial for multiple conditions. Working closely with the Hospital’s pediatricians, neurologists, gastroenterologists, gene therapists, physiologists and computer scientists, Wallace and his team have a singular mission: “Our goal is to revolutionize medicine and to provide a whole new approach to diagnosis and treatment,” he says. “I feel we’re close.” n

Research

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Douglas C. Wallace, Ph.D., director of the Center for Mitochondrial and Epigenomic Medicine, is the first CHOP investigator who is a member of the National Academy of Sciences. He is also an elected member of the Institute of Medicine.

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Craniofacial Surgery

Esteemed plastic surgeon Linton Whitaker, M.D., and renowned artist Nelson Shanks share more than just a friendship and a passion for art and medicine. They also share a belief in the power of those disciplines to heal the body and nourish the soul.

It is their vision — along with collaboration from Scott P. Bartlett, chief, Division of Plastic Surgery, and director, Craniofacial Program at CHOP; Canice E. Crerand, Ph.D., psychologist in CHOP’s Division of Plastic Surgery; and David B. Sarwer, Ph.D., associate professor of Psychology in the departments of Surgery and Psychiatry at University of Pennsylvania School of Medicine — that gave rise to Face to Face: The Craniofacial Program Portrait Project. The program documents the experiences of children and adolescents with craniofacial conditions using a novel intervention — sitting for a portrait.

Between 2008 and 2010, four artists from Studio Incamminati, Shanks’ realist art school in Philadelphia, painted portraits of eight children who have undergone facial reconstructive surgery at The Children’s Hospital of Philadelphia, in an effort to help these children — who often

Portrait PerfectFace to Face: The Craniofacial Program Portrait Project

Kyle, 17

Jessica, 16

experience poor self-esteem, social stigma and rejection — see themselves in a different light.

“The idea is for patients to see themselves the way an artist sees them — as somebody of interest and value — and to bring out qualities that aren’t necessarily obvious at first glance,” says Whitaker, founder of CHOP’s Craniofacial Program.

The first project of its kind in the United States, Face to Face grew out of the Craniofacial Program’s concerns for the psychosocial needs of its patients. Generous support from Craig Aronchick, M.D., a Philadelphia physician, inventor and philanthropist whose own life was affected by facial scars from a childhood car accident, provided initial funding to hire Crerand, a psychologist specializing in facial differences. Crerand coordinated the two-year project, which was made possible by a grant from the Edwin and Fannie Gray Hall Center for Human Appearance at the University of Pennsylvania.

Each portrait was painted over multiple sittings and took roughly six months to complete. They were unveiled publicly at an event in October in the Ruth and Tristram Colket, Jr. Translational Research Building and will be permanently displayed at CHOP. n

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Anthony, 10

Emily, 13Gracie, 11Avery, 9

Brendon, 20Destiny, 11

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Catherine Marchetta, like many patients at The Children’s Hospital of Philadelphia, loved the compassionate care she received at Children’s Hospital so much she didn’t want to leave — even after she became an adult.

But children, even those like Catherine who have chronic medical conditions, grow up and their bodies grow up, too. So, with rare exceptions, they should see physicians who are trained to care for adults. They need to take charge of their own health, assume the role of lead decision-maker and know how to advocate for themselves.

Catherine, now 22, began to learn about ulcerative colitis, an incurable but manageable inflammatory bowel disease, soon after her diagnosis. During the seven years she was cared for at CHOP, her doctors and nurses taught her about her medicines, included her in discussions on potential treatments and helped her live her life to the fullest — even with a chronic disease. “They supported me every step of the way,” says Catherine, “and taught me it is within my power to take control of my disease.” When it was time to step out into the world of adult medicine, she was prepared.

Independence DayCHOP teaches patients to take charge of their health

The transition program that helped Catherine is one of many throughout the Hospital; others include those for patients with cystic fibrosis and sickle cell disease. Additional formal programs are planned, including one to work with patients who have spina bifida.

To help patients along the path to transition, CHOP developed a broad program that builds upon the Hospital’s renowned comprehensive, family-centered care model. New materials educate parents about ways to encourage their children to take responsibility, year by year. Information geared to adolescents and teens explains what age-appropriate tasks they should be able to do on their own. Pediatric residents are trained to incorporate transition into their day-to-day practice. CHOP’s clinicians identify adult providers who understand their patients’ special needs, work to smoothly transfer medical records and sometimes accompany their patients on the first visit to the adult providers.

“My job isn’t completed until I’m comfortable my patients can thrive in the adult world of medicine,” says Nadja Peter, M.D., adolescent medicine specialist and a leader of CHOP’s transition initiative. “It’s not easy to say goodbye, but when they have the skills, they do well.” u

Transition to Adult Care

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Catherine with key members of her CHOP care team from the Center for Pediatric Inflammatory Bowel Disease: senior nurse practitioner Sue Peck, M.S.N., C.R.N.P., and Robert Baldassano, M.D., director of the center.

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My name is Catherine Marchetta, I’m 22 years old, and I’m from Princeton, N.J.

Growing up I was really healthy and athletic. But when I was 13, I became very, very sick and ultimately they diagnosed me with inflammatory bowel disease and, later, ulcerative colitis.

I heard there were just incredible doctors here at CHOP — particularly my doctor, Robert Baldassano — so I came over to Philadelphia. After my first appointment, I kept coming until they kicked me out.

When I came to CHOP, I was immediately impressed by the fact that my nurse practitioner and doctor really tried to educate me in many ways about my illness. They always spoke to me, telling me about different opportunities to learn more about my illness, how to manage it, how to take my medications, and to get support in other avenues, such as the nonprofit organization the Crohn’s and Colitis Foundation.

I also felt like they really gave me the opportunity to become an active partner and contributor to making decisions about my health at a young age.

What I really appreciated and think is so remarkable was that they always encouraged me to pursue my passions, on sports fields and singing and in all my different activities. With my disease, it does have

limitations; but they always really encouraged me to try everything out and then, if something didn’t go well, to make a decision and figure out what was the best balance.

They gave me so much freedom and encouragement and support when I was choosing to move four-and-a-half hours away to go to school up in Boston. But I never felt far from them.

I went to Wellesley College. Once I graduated from college, I knew I needed to transition to an adult doctor. So CHOP did a really fantastic job of giving me recommendations on adult GIs in the area. They gave me a few options and described the different doctors. When I did go to my first appointment with my adult GI, the transition nurse did accompany me, which was very sweet; she went the extra mile. It really helped me to adjust and feel more confident and comfortable meeting my new doctor.

Once I graduated from college, I decided that I would like to move to Italy. I am currently doing research with a gastroenterologist in Bologna.

One of the scariest things about having a diagnosis of a chronic illness is that it follows you for the rest of your life. Through the CHOP transition program, I’ve taken on new responsibilities with my health. Really, I’ve taken control, and I’ve become a more independent patient. n

Transition to Adult Care

With her ulcerative colitis under control, Catherine played on her high school softball and field hockey teams.

Catherine’s Story: In Her Own Words

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Catherine is in Bologna, Italy, conducting research on the effectiveness of treatment for Crohn’s disease and ulcerative colitis in that country.

Environmental Services and Linen Department Team Leader Leon Devine holds the correct patient gown for use in the MRI suite. Devine’s quick thinking helped keep patients in the Sedation Unit safe.

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Something was amiss.

On a quiet Sunday morning, Leon Devine, team leader in the Environmental Services and Linen Department, agreed to fill in for a co-worker who was running late. He headed to the 3 West Sedation Unit to restock sheets, towels and patient gowns. As Devine unloaded a fresh stack of infant gowns, he noticed something that gave him pause: The tiny garments had metal snaps as closures.

It occurred to Devine that on a unit populated with many children who undergo MRI studies, metal on a hospital gown could be dangerous.

Devine had no medical training. He had only worked at The Children’s Hospital of Philadelphia for a few months. But he was intelligent and observant. And thanks in part to his participation

Do No HarmIn CHOP’s culture of safety, every employee has a voice

in CHOP’s Safety Behaviors for Error Prevention training, he felt comfortable voicing his concerns to a nurse and to his supervisor.

“We’ve been trained to identify safety issues,” says Devine. “If you see immediate danger, correct it and communicate.”

He soon learned that his instinct was absolutely correct: Had a baby worn the gown into the MRI suite, the metal in proximity to the unit’s powerful magnet could have caused serious harm. The gowns had mistakenly been directed to the Sedation Unit, in place of ones with cloth ties.

Devine received Hospital-wide recognition for his action, including a special thank-you from President and Chief Operating Officer Madeline Bell.

I will not be ashamed to say “I know not,” nor will I fail to call in my colleagues when the skills of another are needed for a patient’s recovery. – From a version of the Hippocratic Oath sworn by physicians upon graduation from medical school

Patient Safety

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Madeline Bell is passionate about safety.

“I see it as foundational,” says CHOP’s president and chief operating officer. “Families are trusting us to keep their

children safe. It’s basic, but it’s complicated.”

Leading the Hospital’s drive to be America’s safest children’s hospital by 2015 is a challenge. “We get the sickest patients, and we’re humans, prone to error, caring for them.”

But Bell is now seeing the fruits of efforts she has helped put in place over the past two years: institutionwide training in Safety Behaviors for Error Prevention; investment in systems such as the electronic medical record; use of simulation to hone clinicians’ skills; daily safety phone huddles led by the executive team and safety “walk rounds” that keep CHOP leaders like Bell on the front lines.

“I like getting out of my office and hearing from people what works and what doesn’t,” Bell notes. “You can assume, but seeing it firsthand is very different.” u

Walking the Walk

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Like a leading hospital, an aircraft carrier is an extreme environment — an open deck in mid-ocean, where fighter jets take off and land with incredible precision. A place where human error can mean harm or death.

For Jan Boswinkel, M.D., physician leader of CHOP’s Safe Keeping initiative — the Hospital-wide effort dedicated to creating and sustaining a culture of safety — it was the perfect setting to learn about safety behaviors. “So many pieces have to go right,” he says of the ship’s carefully orchestrated operations.

In 2010, Boswinkel went to sea aboard the USS Enterprise, where he spent 24 hours in the ship’s command centers, bridge and flight deck as part of a program for physicians and other healthcare leaders.

Jan’s Excellent AdventureThere he observed a controlled environment with clearly defined roles, staff who paid close attention to details, highly engaged leadership and an emphasis on communication. A hierarchy existed, but people at all levels were encouraged to speak up — including the maintenance person who halted all jet takeoffs because he suspected a loose object had been left on the flight deck. “That’s the kind of culture we want in medicine,” Boswinkel notes. “When you see things that aren’t right you have to say something. If you don’t, you reinforce unsafe behaviors.”

Boswinkel, who is also medical director of the Sedation Service, happened to be on 3 West the morning Leon Devine discovered the potentially dangerous patient gowns. “It was great to see Leon asking those questions,” he says. “And it’s great to see leaders throughout CHOP encouraging and appreciating the effort.” n

Patient Safety

Jan Boswinkel, M.D., spent time in all areas of the carrier USS Enterprise, including the flight deck. He believes there is much CHOP can learn from other industries for which safety is critical.

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Safe takeoffs and landings of fighter jets within a highly contained space require teamwork and meticulous attention to detail.

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The tension is palpable. “He’s seizing,” shouts a nurse. “Call a code blue.” Room 916 South fills with doctors, nurses, respiratory therapists. “I’ll take the lead,” says a second-year critical care fellow. “Start compressions.” A nurse steps up. Press, press, press. “Feel for a pulse.” “Is he seizing again?”

It doesn’t matter that the patient is plastic. It blinks, it bleeds, it breathes, its heart beats. The code team responding is treating it like a real baby in distress. These clinicians are going through a dry run on a soon-to-be-opened patient floor at The Children’s Hospital of Philadelphia, making sure the newly assembled staff and the equipment are ready when real patients arrive.

Children’s Hospital is always ready. Because of its vast expertise, CHOP draws patients with the rarest conditions; it provides cutting-edge treatments; it uses state-of-the-art equipment. All levels of care providers — from the newest-minted clinicians to the world-renowned specialist — want to be at their most confident when they care for their patients.

Practice Makes Perfect CHOP’s simulation training prepares clinicians for the unexpected

Whether it’s rehearsing the safest way to change a long-term intravenous line, choreographing the delivery of a baby with an extremely rare birth defect or getting a head start on training at the Critical Care Fellow Boot Camp each summer, CHOP simulates scenarios clinicians will face so they can rehearse safely — first to competence, then to excellence.

In CHOP’s pioneering hub-and-spoke training model, some simulations take place in a traditional simulation center, a mock patient room with an adjacent classroom; others take place in the units or operating rooms where patient care happens. Some simulations use high-tech medical manikins; others use trained actors as patients or parents. Still others, like for interventional radiology and robotic surgery, use special virtual reality training equipment, similar to the way pilots use a flight simulator.

“These simulators are all just tools,” says Vinay M. Nadkarni, M.D., medical director of CHOP’s Center for Simulation, Advanced Education and Innovation. “It’s really about the education and practicing in realistic situations. It’s about being the very best we can be.” u

Simulation Training

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Doctors in training, experienced specialists and surgeons, and family members all benefit from learning and perfecting skills through simulated training. SimBaby™ helps it happen.

Pratichi Kothari Goenka, M.D. pediatric chief resident

SimBaby™

Vinay Nadkarni, M.D.medical director, Center for Simulation,

Advanced Education and Innovation Christina Mohammedmother of CHOP patient Omar Jr.

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The actions of the manikin in each exercise are monitored and changed by a simulation operator controlling a computer.

Simulation Training

They’ve Come a Long Way, BabyThese are not a child’s baby-dolls. With a total price tag of more than $1 million, the 18 medical manikins, additional body parts and related high-tech equipment used for simulation training at Children’s Hospital are well worth the investment for medical personnel and, ultimately, our patients.

Manikins are as tiny as a 1 pound, 1 ounce infant and as big as an older teen. Their realistic bodies hide sophisticated electronics that allow them to act and react as a real child or adolescent would. The accompanying computer gives practitioners the manikin’s vital signs in real time, showing if resuscitation efforts are improving the heart rate and oxygen levels.

Manikins can be preprogrammed to act as if they’re having a seizure, a cardiac arrest, a blocked airway, an allergic reaction or a multitude of other problems. Switch out an arm and a nurse can administer an IV (a pouch inside accumulates the fluid). Attach a different leg and a physician can stabilize and cast a broken bone or suture a deep cut. To simulate rashes or other skin conditions, a manikin may wear makeup.

The Center for Simulation, Advanced Education and Innovation uses manikins in more than 800 simulations each year — all preparing CHOP clinicians to provide the safest, most efficient, state-of-the-art care to children. u

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Different sizes, ages and capabilities of the medical manikins and their parts allow clinicians to practice treating a wide variety of conditions and emergencies.

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Attending physicians, nurses, radiology techs, trauma surgeons and respiratory therapists converge to “save” SimMan®.

Simulation Training

Ready for ChangeEven the best clinicians need practice, want practice. As procedures grow more complex and equipment becomes more sophisticated, physicians and other practitioners at Children’s Hospital constantly strive to improve their skills so they stay on top. That takes practice, evaluation and feedback, and then more practice.

“Whenever you bring in new techniques, new technology or new equipment, you don’t want to practice on patients, but in simulation,” says Nadkarni. “You test the environment to find potential or real errors that could happen. Then you fix any problems before they ever happen with real patients.”

For surgeons, CHOP created a new program called STACK — Surgical Training Advancement Competency and Knowledge — to practice minimally invasive surgery, in which surgeons manipulate instruments remotely, using tiny lights and cameras in the patient’s body to guide them. “We will have the same equipment in STACK as in the OR: same screens, same cameras, same everything,” says Thane Blinman, M.D., director of Minimally Invasive Surgery. “You deliberately practice until it becomes second nature. Our mission is for surgeons to know what every single piece of equipment does and how to use it — like a marine who can fieldstrip his rifle in his sleep.” u

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The patient is turned over, exposing the bleeding gunshot wound in his back.

Simulation Training

Christina Mohammed and Omar Hardy could not take their baby, Omar Jr., home from Children’s Hospital without the skills to care for him and the confidence that they could use them.

“After he had a plug in his airway and we saw all the nurses and doctors rush in, we knew how serious this is,” says Omar. “Everything they were doing to him, we needed to be able to do at home. It scared me.”

Omar Jr., 10 months, was diagnosed with spinal muscular atrophy type 1 at 6 months and spent three months at CHOP last year after he had a crisis near his home in the Poconos. The diagnosis means his muscles are weak, so his breathing is aided by a bi-level positive airway pressure ventilator, known as BiPAP, and his caregivers need to periodically suction his airway to clear mucus.

“We were at his bedside all the time, so we already knew how to do the routine things: suctioning, putting him on BiPAP, giving him coughilator treatments,” Christina says. “But handling an emergency is different.”

Simulation was the confidence builder Christina and Omar needed to feel empowered to apply the individual skills they had learned in the heat of the moment of an unexpected

Confidence Is Power event. Omar Jr.’s doctor, Richard Lin, M.D., used a SimBaby medical manikin preprogrammed to go through a medical emergency. The parents needed to determine the problem and address it.

“At first it was surreal — sort of like playing house,” Omar says. “But then it got intense. We were sweating.”

Lin didn’t coach or interfere during the simulation, but reviewed what he observed they did right and wrong afterward. Christina says, “He studied our movements and communication and suggested ways to do things better.”

Parents of spinal muscular atrophy patients at CHOP go through simulation training for emergencies, such as a drop in the child’s oxygen level or an equipment failure, as many times as they need to feel comfortable they’ll be able to help their child through a crisis once they’re home.

“It’s one thing to ask a parent, ‘If this happens, what will you do?’” says Lin. “It’s another thing to have a crisis and the parent has to figure out what’s going on and decide what to do.”

The Hardy family is ready. “We may face serious situations and we don’t want to panic,” Omar says. “The simulations definitely raised our confidence.” n

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Christina and Omar are better prepared to care for Omar Jr. because of simulation training.

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Erin O’Donnell, R.N., B.S.N., a nurse in the Pediatric Intensive Care Unit at The Children’s Hospital of Philadelphia, understands seventh-grade girls. “Call it ‘exercise’ and you don’t get the greatest response. Call it ‘hip-hop’ and they love it,” she says.

That understanding led O’Donnell to teach hip-hop dance routines to girls at St. Francis de Sales School in West Philadelphia as her project for CHOP’s Community Nursing Advocacy Fellowship. And while she’s got the girls’ attention, she teaches quick health lessons at each of the weekly dance sessions.

The girls also laugh, tease, jump, sing, wiggle, pose and sweat.

“It’s a workout, but it’s fun,” says Jailyn between dances. “We get to dance and hang out with our friends, and Erin’s amazing. She tells us about our

All the Right Moves Fellowships enable nurses to teach kids in the community about health

bodies and how they work, so we can take better care of ourselves.”

O’Donnell can see that in addition to dance moves, the girls are making a move toward healthier lifestyles. “I definitely see them making healthier snack choices; water instead of soda, for example,” she says. “They ask a lot of questions and tell stories that relate to the day’s topic. But the dancing is definitely their favorite part.”

That’s OK. For O’Donnell, who’s been dancing since she was 3, it’s her favorite part, too.

“I applied for the fellowship because I wanted to volunteer in the community,” she says. “I knew St. Francis was a small school and could use some help. This is great for the girls, and it’s an opportunity for me to have fun and represent CHOP in a positive way.” u

Nursing Advocacy

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The girls at St. Francis de Sales School in West Philadelphia get a real lift out of the hip-hop dance classes led by a Community Nursing Advocacy Fellow from CHOP. Their health gets a lift, too.

Erin O’Donnell, R.N., B.S.N., blends her dance and health backgrounds to lead the group.

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Children’s Hospital sits in West Philadelphia — a community of incredible diversity and, in many ways, incredible needs.

The Community Nursing Advocacy Fellowship, the only fellowship of its kind in the nation, was created to help meet those needs and, at the same time, provide CHOP nurses with an outlet for their desire to step outside the Hospital buildings and serve in the community.

Many nurses care for the sickest children every day in their jobs. They appreciate working with healthy children and youth, and are energized by figuring out novel ways to help them stay healthy. Whether helping parents toddler-proof their homes or teaching second-graders about sugar-free drinks or enticing teenage girls to exercise, nurse fellows give of themselves and gain a better understanding of the community.

Generous donations from the 1675 Foundation and Carol Ware Charitable Lead Trust have allowed the program to grow from six fellows in 2004 to 10 spots now. The nurses initially spend their allotted 12 hours a month visiting nonprofits, shelters, schools and family court. Then they develop a project drawn from that experience.

Meeting People Where They Are“Until you spend time with families in a homeless shelter, you can’t really understand their challenges,” says Mary Polk-Pretsch, R.N., M.S.N., who works with acute patients at CHOP. “Mothers have nowhere to store milk or fresh food. So if they miss the set mealtime, their only alternative is fast food. Children don’t have a safe place to play outside, so they don’t get enough exercise.”

Her project got mothers and their children, who were residents of ECS St. Barnabas Mission, exercising together and learning about nutrition. “The kids had fun, and the moms learned they can be good role models for their children,” Polk-Pretsch says.

“I got a better perspective on how healthcare is tied to family dynamics and lifestyle,” says Derek Waters, R.N., B.S.N., a primary care nurse who combined math, science and fun activities to teach 7-year-olds about nutrition at Penn Alexander School.

Beth Henry, B.S.N., C.P.N., has spent 24 years as a CHOP nurse but says her knowledge grew exponentially during her fellowship. “Every experience was an adventure, and it taught me to think about families and their circumstances in a whole new way. It helped me be a better nurse.” n

The map at the right shows the locations of all Community Nursing Advocacy Fellowship projects. Some locations have had multiple projects.

Nursing Advocacy

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Philanthropy

In fiscal year 2010, 66,000 individuals contributed a total of $52 million to The Children’s Hospital of Philadelphia. Much of that support was generated through special events run by The Children’s Hospital of Philadelphia Foundation.

At the 2009 Carousel Ball, CHOP’s biennial black-tie gala, donors danced the night away in support of CHOP’s Diabetes Center and Healthy Weight Program. At the Daisy Day Luncheon in April, a fashion show by designer Oscar de la Renta brought the gift of childhood to many children around the world by supporting the Global Health Department. From the Blue Tag Gala benefiting the Sickle Cell Center to Evening of Hope’s concert by Mandy Patinkin to fight pediatric inflammatory bowel disease, our generous donors turned festive occasions into opportunities to better the health of children.

Good Times, Great CauseEvents bring the Gift of Childhood to our patients

Many annual events hit new records. The 2009 Four Seasons Parkway Run drew an unprecedented 7,100 participants and raised $580,000 for the Cancer Center at CHOP. The second annual ‘All In’ for Kids Poker Tournament, held at the Mandarin Oriental in New York, brought in more than $823,000 for the Division of Neurosurgery.

Community-organized events, whether they are golf tournaments, runs/walks, dance-a-thons, bake sales or lemonade stands, are also an important component to giving. These events — and the dedicated volunteers who run them — raise hundreds of thousands of dollars each year to help CHOP help children.

It is no exaggeration to say the generosity of our donors allows Children’s Hospital to remain the world’s best in pediatric patient care and research, a place that gives hope to hundreds, if not thousands, of families every single day. u

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Philanthropy – Events in Review

Children’s Circle of CareCHOP’s Children’s Circle of Care members attended the annual conference in Seattle where CHOP’s own Robert Baldassano, M.D., director of the Center for Pediatric Inflammatory Bowel Disease and holder of the Colman Family Endowed Chair in Pediatric Inflammatory Bowel Disease, was a featured speaker.

Gelatin OlympicsThe Kids-N-Hope Foundation’s crazy and wacky 16th Annual Gelatin Olympics raised more than $23,000 for the Children’s Seashore House at Children’s Hospital.

Hope Lives Here Campaign CelebrationCHOP celebrated the close of the Hope Lives Here campaign, which raised $476.5 million, with a special reception to honor the Hospital’s most dedicated supporters. More than 200 guests gathered at Karamoor, the magnificent estate owned by CHOP supporters Nicholas and Athena Karabots (above left, cutting the CHOP cake with Robin and Steven M. Altschuler, M.D., CHOP CEO).

Alex’s Lemonade StandThe CHOP community hosted 30 Alex’s Lemonade Stands, raising more than $50,000 for cancer research at Children’s Hospital. Audrey Evans, M.D., (above with Garrett M. Brodeur, M.D., Oncology, left, and John Maris, M.D., director, Center for Childhood Cancer Research, and chief, Division of Oncology), was honored with the Pitcher of Hope Award.

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Wade’s Walk to WorkWade Wilson, store manager of Rite Aid #4601 in Stratford, N.J., walked to work while also helping to raise money for Children’s Miracle Network at Children’s Hospital. Wade walked 23 miles from his home in Logan Township, N.J., to his store. With help from his associates, Wade raised more than $2,500 for CMN at CHOP!

98.1 WOGL RadiothonThe Eighth Annual 98.1 WOGL Loves Our Kids Radiothon took over the Colket Atrium of the Main Building for two days and raised $419,010. WOGL’s Ross Brittain and the Breakfast Club and families that came to the atrium had visits with Phillies pitcher Brad Lidge, Miss Pennsylvania, Miss New Jersey and Miss Delaware.

Biesecker Pediatric Liver CenterMya and Ava Longacre recently visited the Hospital to make a wonderful donation to the Biesecker Pediatric Liver Center. Mya and Ava are the granddaughters of Fred and Suzanne Biesecker, for whom the center is named. By holding yard sales, selling lemonade and old bikes, and asking friends to contribute, the girls were able to raise a total of $1,678!

Going ‘All In’ for KidsCelebrities, professional poker players, donors and CHOP trustees tried their luck at the second annual ‘All In’ for Kids Poker Tournament at the Mandarin Oriental Hotel in New York City. Honorary chairs and presenting sponsors Jim and Nancy Minnick (above, flanking top 10 finisher Nicole Rowe), along with 120 players, raised more than $823,000 for CHOP’s Division of Neurosurgery. M.J. Serota finished first followed by Andrew Pauxtis and event co-founder Dan Shak.

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Philanthropy – Events in Review

An Evening with Dick VermeilMembers of CHOP’s Legacy Advisors group enjoyed an evening with Dick Vermeil. The beloved former coach of the Philadelphia Eagles (above with George Reath, emeritus CHOP trustee and chair of the Lewis Society, and his wife, Ann Reath) spoke about his own experience at CHOP as a grateful grandparent.

Women’s Committee Holiday BoutiqueMore than 500 people kicked off the holiday season at the Merion Cricket Club by supporting the Women’s Committee’s 44th Annual Holiday Boutique. More than $270,000 was raised to support patient care, research and education.

Four Seasons Parkway Run/WalkA record-breaking 7,100 people gathered on Logan Circle for the Four Seasons Parkway Run/Walk. More than $580,000 was raised for CHOP’s Cancer Center.

Ride Ataxia PhiladelphiaMore than 350 participants took part in the first Friedreich’s Ataxia Research Alliance (FARA) Ride Ataxia – Philadelphia, going on 50-, 25- and 10-mile rides. An additional 100 children and family members enjoyed fall family fun activities. Pictured: Kyle Bryant, Ride Ataxia founder and director, alongside Ed Ramsey, FARA board member.

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Eighth Annual Buddy Walk® and Family Fun DayMore than 4,000 people came to Villanova University to walk, moon bounce, dance, sing and support CHOP’s Trisomy 21 (Down syndrome) Program at The Children’s Hospital of Philadelphia Eighth Annual Buddy Walk® and Family Fun Day. More than $225,000 was raised for patient care, research and education.

Walk for HopeThe first-ever Walk for Hope raised more than $35,000 for the Center for Pediatric Inflammatory Bowel Disease (IBD) at CHOP. More than 250 runners and walkers took to the 5K course at the event, organized by members of the Family Research Council, a volunteer group of IBD patient families and friends that supports research at CHOP.

Carousel Ball Raises $1.5 MillionThe Carousel Ball, Children’s Hospital’s signature, biennial black-tie dinner dance, was a glamorous affair. More than $1.5 million was raised for the Diabetes Center and the Healthy Weight Program at CHOP. From left, Steven M. Altschuler, M.D., CHOP CEO, and his wife, Robin, with event co-chairs Lynne and Bill Garbose.

Monte Carlo NightThe Philadelphia Marriott Business Council hosted its fourth annual Monte Carlo Night benefiting Children’s Miracle Network at CHOP, raising more than $65,000 for patient care programs at Children’s Hospital.

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Philanthropy – Events in Review

Dedication of the Ruth and Tristram Colket, Jr. Translational Research BuildingOn June 9, a new chapter in the history of The Children’s Hospital of Philadelphia began as the Ruth and Tristram Colket, Jr. Translational Research Building was officially dedicated. More than 250 people attended the banner cutting for the 11-story, 450,000-square-foot building. Ruth and Tristram Colket got help from their grandchildren cutting the ribbon.

Philadelphia International Auto Show Black Tie Tailgate Preview GalaMore than 3,000 people attended the Philadelphia International Auto Show Black Tie Tailgate Preview Gala. Co-chairs of the Preview Gala were CHOP CEO Steven M. Altschuler, M.D., and his wife, Robin, and Dom and Karen Conicelli. The Auto Dealers CARing for Kids Foundation, one of CHOP’s most dedicated and generous supporters, presented Altschuler (above, left) with the final check, which completed the Foundation’s pledge of $2 million to CHOP. Also shown are Scott Lustgarten, Dom Conicelli and Kevin Mazzucola.

Healthy Kids DayThe second annual Healthy Kids Day added a new feature to its lineup of educational and fun activities for kids. This year, more than 300 children in sixth to 12th grades participated in a fitness walk around The Mann Center for the Performing Arts the morning of Healthy Kids Day. The afternoon event offered families healthy food, tons of health-related information and plenty of fun activities for the kids. Hip Hop Harry and the Laurie Berkner Band performed.

Founders Society GatheringMembers of the Founders Society at Children’s Hospital gathered at the historic Merion Golf Club with host Clark Hooper Baruch, chair of the Founders Society and Hospital trustee. The reception honored those who have contributed more than $1,000 to the Hospital in recent fiscal years. Loyal 25-year donors Lisa (left) and Dick Carr are with Baruch.

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Chairman’s Circle DinnerThe inaugural Chairman’s Circle Dinner, hosted by chairman of CHOP’s Board of Trustees Stephen B. Burke, was held at the Four Seasons Hotel Philadelphia. The Chairman’s Circle honors the Hospital’s most generous donors, those who have given $1 million or more in cumulative gifts. Each member was recognized at the event and received a token of appreciation. Above, David Oberkircher and trustee George Lemmon Jr. chat with Burke.

Raphaely DedicationA plaque was unveiled in honor of Russell Raphaely, M.D., who was director of CHOP’s Pediatric Intensive Care Unit from 1972-1996. The honor was made possible by a gift from an anonymous donor. Guests attended a luncheon and heard moving remarks from a patient family whose daughter received exceptional care from Raphaely. Next to the plaque are, from left: Wilson J.C. Braun III, Marianne Raphaely, Mary C. Braun, Courtney Braun, Raphaely, Bernard S. Kaplan, M.B.B.Ch., chief, Division of Nephrology, Wilson J.C. Braun Jr. and CHOP CEO Steven M. Altschuler, M.D.

Make Some NoiseThe Cure Kids Cancer Foundation raised more than $100,000 for cancer research at a black-tie dinner with live and silent auctions. Malcolm Sutherland-Foggio (above with mom Julie Sutherland, John Maris, M.D., and oncologist Richard Womer, M.D.) returned to CHOP to present the event proceeds to the Cancer Center.

Childhood Friends Third Annual Wine TastingThe Childhood Friends Third Annual Wine Tasting was held at the new Daniel Stern restaurant R2L, where more than 100 guests enjoyed wines from three wineries. The event raised $28,000 for research, education and patient care programs at CHOP.

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Philanthropy – Events in Review

54th Annual Daisy Day® Luncheon and Fashion ShowThe 54th Annual Daisy Day Luncheon and Fashion Show, the largest daytime fundraising event in Philadelphia, featured designer Oscar de la Renta’s Fall 2010 collection and raised more than $1.1 million to benefit Global Health. From left: Rodney Finalle, M.D., director, Global Health; Steven M. Altschuler, M.D., CHOP CEO; Nancy A. Wolfson, event chair; David Pincus, Daisy Day 2010 Honorary Chair; and his wife, Geraldine Pincus.

Huddle Up for AutismMore than 4,000 people attended Huddle Up for Autism at Lincoln Financial Field. The day was presented by the Philadelphia Eagles and benefited the Center for Autism Research at Children’s Hospital. It raised nearly $80,000 for autism research. Attendees had the opportunity to meet Eagles players and get up close and personal with Swoop, the Eagles’ mascot.

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Individuals $27,017,099Foundations $6,694,161

Faculty Practices $7,765,600

Corporations $11,084,106

CHARITABLE GIVING BY SOURCE – FISCAL YEAR 2010Outright gifts and pledges

TOTAL $52,560,966

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An organization is only as good as its people — and fortunately for CHOP, our clinicians, researchers, administrators and other staff are among the very best in their fields. In 2010, many of our employees received national recognition for their accomplishments, and we welcomed a number of new leaders. Eighteen are highlighted here.

Get to know the CHOP innovators who are moving pediatric healthcare forward, one stunning achievement at a time. u

18 Ways To Be ExtraordinaryA year filled with awards, recognitions and appointments

People

Apkon joined CHOP as senior vice president, chief medical officer and patient safety officer. Previously, Apkon served in various leadership roles in the Yale New Haven Health System. He was vice president and executive director of the 155-bed Children’s Hospital division, and he also served as vice president for performance management.

Michael Apkon, M.D., Ph.D., M.B.A.Senior Vice President and Chief Medical Officer

Adamson, an internationally recognized leader in pediatric cancer drug development, was elected to serve as chair of the Children’s Oncology Group, a consortium of more than 200 leading children’s hospitals, universities and cancer centers worldwide. He will oversee an annual budget of $30 million, and more than 100 clinical trials involving thousands of children with cancer and 5,000 pediatric oncology experts.

Peter Adamson, M.D.Chief, Division of Clinical Pharmacology and Therapeutics

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Benton was named psychiatrist-in-chief and executive director of the Department of Child and Adolescent Psychiatry and Behavioral Science. She holds membership and leadership positions in several professional and scientific societies, including the American Academy of Child & Adolescent Psychiatry and the American Board of Psychiatry and Neurology.

Bell, who began her career as a nurse, this summer took on the responsibilities of president of Children’s Hospital in addition to being chief operating officer. In her expanded role, she will have greater accountability for day-to-day operations of the Hospital and Care Network, and for strategic and operating plans.

Tami Benton, M.D.Psychiatrist-in-Chief and Executive Director, Child and Adolescent Psychiatry and Behavioral Science

Madeline BellPresident and Chief Operating Officer

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Cohen was elected president of the board of trustees for the American Board of Pediatrics (ABP), the certifying organization for all pediatricians and pediatric subspecialists. The ABP establishes and implements requirements for certification and advances the science, education, study and practice of pediatrics. Although ABP certification is voluntary, nearly all qualified pediatricians seek this recognition.

Christian was named first medical director of the City of Philadelphia Department of Human Services, where she will oversee improving the health and well-being of thousands of children under the protective care of DHS.

Alan Cohen, M.D.Physician-in-Chief and Chair, Department of Pediatrics

Cindy Christian, M.D.Director, Safe Place: The Center for Child Protection and Health

Bessler, one of the world’s foremost experts on bone marrow failure, was recruited to Children’s Hospital to create and lead the Pediatric and Adult Comprehensive Bone Marrow Failure Center, a cradle-to-old-age, basic-science-to-clinical-care program for patients with these conditions and their families. This is one of the first such programs in the world.

Monica Bessler, M.D., Ph.D.Director, Pediatric and Adult Comprehensive Bone Marrow Failure Center

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Croner’s extensive experience in strategic planning and execution, aligning HR and business objectives, leadership development, performance management, and staff development made him the perfect choice to take on the role of senior vice president of Human Resources.

Furth came to Children’s Hospital from Johns Hopkins Children’s Center, where she treated patients and was director of pediatric nephrology. She serves as principal investigator of a nationwide, 10-year, multicenter clinical research study on chronic kidney disease in children.

Curran was elected to the prestigious Institute of Medicine, a nonprofit that recognizes individuals who have made significant contributions to the field of medicine and educates the government and the public about health and medical issues. Only 65 members are elected each year.

Robert CronerSenior Vice President, Human Resources

Susan Furth, M.D., Ph.D.Chief, Division of Nephrology

Tom Curran, Ph.D., FRSDeputy Scientific Director, The Children’s Hospital of Philadelphia Research Institute

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Haines, previously senior vice president for Strategy and Program Development, was named senior vice president for International Medicine. She leads CHOP’s international initiatives, including growing the volume of international patients at CHOP, developing professional education and clinical collaborations with healthcare systems around the world, and overseeing Global Health humanitarian programs in the Dominican Republic and Botswana.

Gorman joined CHOP as senior vice president and chief nursing officer in October 2009. Before joining CHOP, she was vice president of quality and clinical support services at Children’s National Medical Center in Washington, D.C.

Golden’s promotion from interim to pathologist-in-chief is only the most recent of his leadership positions at CHOP. A staff neuropathologist at CHOP since 1996, he was chief of the Center of Developmental Biology and former chair of the Institutional Animal Care and Use Committee. Golden currently holds three National Institutes of Health grants.

Cynthia HainesSenior Vice President, International Medicine

Kathleen Gorman, M.S.N., R.N.Senior Vice President and Chief Nursing Officer

Jeffrey Golden, M.D. Pathologist-in-Chief

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Hobbie was named a fellow of the American Academy of Nursing, an honor bestowed on nursing professionals who have made significant contributions to the field. She came to CHOP as a graduate student and was hired in 1983 to help establish the Cancer Survivorship Program, the first comprehensive program of its kind.

Hogarth was honored as the Nonprofit Marketer of the Year by the American Marketing Association and the American Marketing Association Foundation. Fifty-eight people were nominated for the award, which honors extraordinary leadership and achievement in the field of nonprofit marketing.

Hicks, a nationally renowned medical educator, was named director of CHOP’s Pediatric Residency Training Program, one of the largest such programs in the country with 144 residents. She most recently directed the pediatric residency program at the University of Texas Southwestern Medical Center, expanding the program by 25 percent in five years.

Wendy Hobbie, C.P.N.P., M.S.N., F.A.A.N.Coordinator, Cancer Survivorship Program

Stephanie Hogarth Chief Marketing Officer

Patricia Hicks, M.D.Director, Pediatric Residency Training Program

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Orange received the prestigious Judson Daland Prize for Outstanding Achievement in Clinical Investigation from the American Philosophical Society, an organization founded by Benjamin Franklin in 1743. The prize recognizes outstanding achievements in patient-focused research.

Jordan Orange, M.D., Ph.D.Attending Physician, Immunology Service

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Since 1974, Ludwig has taken leadership roles at CHOP in the Emergency Department, the Division of General Pediatrics, the Medical Education Program and, most recently, International Medicine. His leadership in the field of pediatrics nationwide was recognized with the 2010 Joseph W. St. Geme Jr. Leadership Award from the Federation of Pediatric Organizations.

Stephen Ludwig, M.D.Senior Adviser for Medical Education

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The 2010 Annual Report, Fast

Forward, is dedicated to the memory

of Richard M. Armstrong Jr.,

who served as chairman of The

Children’s Hospital of Philadelphia

Board of Trustees for nearly 20 years.

A leader, a visionary and a great

friend of the Hospital, Dick

consistently challenged us to

“fast forward” our efforts to

improve children’s lives.

Dedication

Richard M. Armstrong Jr. 1937 – 2010

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Numbers

Financial SummaryThe Children’s Hospital Foundation and Controlled Affiliates

For the fiscal years ended June 30

For the fiscal years ended June 30

Sources of Revenue FY 2010 FY 2009 FY 2008 Net Patient Service Revenue $1,476,436,000 $1,384,366,000 $1,287,016,000 Other Operating Revenue (1) 38,618,000 24,528,000 179,443,000 Contributions (2) 51,853,000 60,782,000 47,922,000 Research 203,667,000 178,642,000 188,204,000 Total Sources of Revenue $1,770,574,000 $1,648,318,000 $1,702,585,000

Uses of Revenue

Salaries, Wages and Employee Benefits $862,959,000 $803,644,000 $727,415,000 Supplies and Expenses 315,450,000 345,263,000 340,334,000 Depreciation 120,124,000 109,030,000 99,582,000 Interest 8,548,000 8,235,000 12,589,000 Research Expenses 257,893,000 248,638,000 232,418,000 Uncompensated Care 51,494,000 72,812,000 69,636,000 Provisions for Programmatic Investments 154,106,000 60,696,000 220,611,000

Total Uses of Revenue $1,770,574,000 $1,648,318,000 $1,702,585,000 (1) FY 2008 includes net proceeds from the sale of the RotaTeq® vaccine royalty rights in the amount of $156 million (2) Includes unrestricted, temporarily restricted and permanently restricted contributions

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Combined Balance Sheet The Children’s Hospital Foundation and Controlled Affiliates

FY 2010 FY 2009 FY 2008 Assets

Cash and Short-term Investments $159,612,000 $96,682,000 $73,003,000 Receivables 220,919,000 225,734,000 207,440,000 Other Current 88,539,000 159,214,000 195,917,000

Total Current Assets 469,070,000 481,630,000 476,360,000

Investments 1,265,278,000 1,091,365,000 1,540,019,000 Property, Plant and Equipment, Net 1,533,282,000 1,480,420,000 1,310,062,000 Other Assets 18,263,000 22,026,000 11,442,000

Total Assets $3,285,893,000 $3,075,441,000 $3,337,883,000

Liabilities and Net Assets

Current Portion of Long-term Debt $11,779,000 $11,252,000 $10,751,000 Accounts Payable and Accrued Expenses 263,491,000 297,449,000 348,380,000

Total Current Liabilities 275,270,000 308,701,000 359,131,000

Long-term Debt 594,931,000 606,710,000 617,963,000Other Liabilities 247,989,000 221,967,000 162,731,000 Unrestricted Net Assets 1,928,027,000 1,707,323,000 1,911,391,000 Temporarily Restricted Net Assets 109,830,000 94,459,000 125,638,000 Permanently Restricted Net Assets 129,846,000 136,281,000 161,029,000Total Net Assets 2,167,703,000 1,938,063,000 2,198,058,000

Total Liabilities and Net Assets $3,285,893,000 $3,075,441,000 $3,337,883,000

For the fiscal years ended June 30

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Numbers

Hospital and CHOP Care Network Statistics

Outpatient Visits 2010 2009 2008 Specialty Care 310,394 289,265 281,785 Kids First 617,455 605,241 599,712 Primary Care 115,464 107,689 99,845 Emergency 85,690 85,450 82,058 Day Medicine 20,554 21,910 22,001 Day Surgery 17,648 17,162 15,912 Total 1,167,205 1,126,717 1,101,313

HOSPITAL ADMISSIONS & PATIENT DAYS

Hospital Admissions

Patient Days

2010 2009 20080

134,363

26,714

130,088

25,699

139,424

28,106

NUMBER OF BEDS

2010

2009

2008

1000 200 300 400

459

443

421

NUMBER OF EMPLOYEES

2010

2009

2008

20000 4000 6000 8000 10000

9,934

9,116

9,762

150,000

120,000

90,000

60,000

30,000

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Admissions

ADMISSIONS FROM PENNSYLVANIAby Selected Counties

Berks 360Bucks 1,876 Chester 897 Delaware 2,714 Lackawanna 108Lancaster 210Lehigh 233 Montgomery 2,696 Northampton 193Philadelphia 9,802Other 624

Total: 19,713

ADMISSIONS FROM NEW JERSEYby County

Atlantic 556Bergen 57Burlington 1,338 Camden 1,536 Cape May 174Cumberland 312Essex 86Gloucester 842Hudson 49Hunterdon 76 Mercer 491 Middlesex 259 Monmouth 338Morris 42 Ocean 659Passaic 37 Salem 80Somerset 114Sussex 21Union 94Warren 51

Total: 7,212

RESEARCH STATISTICSFiscal Year 2010 All Sources of Funding

External Grants $161,639,180 Endowment 6,361,173*Hospital 41,743,170+ Other 16,658,134^

Total $226,401,657 * Endowed chairs only+ General research endowment and capital

^ Core facilities, royalty, rental and contributions

Breakdown of External Funding

Federal $115,101,703Federal-Stimulus 10,938,785 Industrial 10,544,101 State/Local 4,327,339 Foundation 11,830,300 Other 8,896,952

Total $161,639,180

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About CHOP

MANAGEMENTTHE CHILDREN’S HOSPITAL OF PHILADELPHIA

Chief Executive OfficerSteven M. Altschuler, M.D.

President and Chief Operating OfficerMadeline Bell

Executive Vice President and Chief Scientific OfficerPhilip R. Johnson Jr., M.D.

Executive Vice President and Chief Administrative OfficerMargaret M. Jones

Executive Vice President and General CounselJeffrey D. Kahn, Esq.

Executive Vice President and Chief Development OfficerStuart P. Sullivan

Executive Vice President and Chief Financial OfficerThomas J. Todorow

Senior Vice President and Chief Medical OfficerMichael Apkon, M.D., Ph.D.

Senior Vice President, Human ResourcesRobert Croner

Senior Vice President and Chief Nursing OfficerKathleen Chavanu Gorman, M.S.N., R.N.

Senior Vice President, Outpatient and Clinical ServicesThomas R. Dole

Senior Vice President, International MedicineCynthia Haines

Senior Vice President, Clinical Support ServicesCharles S. Hough

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Senior Vice President, CHOP Care NetworkAmy J. Lambert

Senior Vice President, Health Information Management and Family ServicesMichele Lloyd

Senior Vice President and Chief Investment OfficerNicholas P. Procyk

Senior Vice President and Chief Information OfficerBryan Wolf, M.D., Ph.D.

Vice President, Finance, and Corporate ControllerDavid F. Alexander

Vice President, Private Investments Andrew Deitch

Vice President, Patient Access and Revenue CycleMartha M. Parra

Vice President, Supply ChainJoni Rittler

Vice President, Research Administration and Finance Deputy Administrative DirectorMary A. Tomlinson

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About CHOP

TRUSTEESThe Joint Boards of Trustees for The Children’s Hospital of Philadelphia Foundation and The Children’s Hospital of Philadelphia

ChairmanStephen B. Burke

Vice ChairmenTristram C. Colket, Jr.R. Anderson Pew

President and Chief Executive OfficerSteven M. Altschuler, M.D.

SecretaryJeffrey E. Perelman

TreasurerJohn Milligan, C.P.A.

Assistant TreasurerThomas J. Todorow

General Counsel and Assistant SecretaryJeffrey D. Kahn, Esq. (Acting)

Assistant SecretaryMargaret M. Jones

Boards of TrusteesN. Scott Adzick, M.D., M.M.M.Steven M. Altschuler, M.D.Clark Hooper BaruchFred N. BieseckerAminta Hawkins Breaux, Ph.D.Troyen Brennan, M.D.Mortimer J. Buckley IIIStephen B. Burke Dominic J. CarusoAlan R. Cohen, M.D.Tristram C. Colket, Jr.Arthur Dantchik

For the 2010 fiscal year, July 1, 2009, through June 30, 2010

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Mark FishmanLynne L. Garbose, Esq.Anthony A. LatiniGeorge B. Lemmon Jr.James L. McCabeJohn Milligan, C.P.A.Asuka NakaharaJeffrey E. PerelmanR. Anderson Pew Gerald D. Quill Aileen Kennedy RobertsDavid B. RubensteinStuart T. Saunders Jr., Esq.Anne Faulkner SchoemakerSalem D. ShuchmanAudrey C. Talley, Esq.Binney WietlisbachNancy WolfsonDirk E. Ziff

Ex-Officio Jeffrey A. Fine, Psy.D.Jeffrey Golden, M.D. Kathleen Gorman, M.S.N., R.N.William J. Greeley, M.D. Diego Jaramillo, M.D., M.P.H. Mark Magnusson, M.D.

Emeritus Richard M. Armstrong Jr.*, Honorary ChairmanLeonard AbramsonJohn BiswangerWillard BoothbyRuth M. ColketArmin C. FrankPeter C. MorseGeorge Reath Jr.Richard D. Wood Jr.

*Deceased

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About CHOP

Executive Council of Volunteer OrganizationsAUXILIARY OF THE CHILDREN’S HOSPITAL OF PHILADELPHIAPresidentMarianne Raphaely

BIG HEARTS TO LITTLE HEARTSPresidentLynne Ramsay

BRYCE’S BRIDGE OF HOPECo-FoundersJudy and Jeff Hansen

CHILDHOOD FRIENDSPresidentKaty Friedland

CHILDREN’S SEASHORE HOUSE AUXILIARY OF ATLANTIC COUNTYPresidentSally Parsly

FRIEDREICH’S ATAXIARepresentativeHolly Hedrick, M.D.

FRIENDS OF TRISOMY 21RepresentativeGrace Wadell

IBD FAMILY RESEARCH COUNCILCurrent ECVO President Jeffrey FineRepresentativeNancy Fine

LYNN SALIGMAN LEAGUECo-PresidentsJoni BlumIlene Silverman

MIRIAM’S KIDS RESEARCH FOUNDATIONExecutive DirectorHelena Quigley

SICKLE CELL COMMUNITY ADVOCACY COMMITTEEImmediate Past ECVO President Darlene LoganRepresentativeSandra Becks

WOMEN’S COMMITTEEPresidentClaire Hardon

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About CHOP

ENDOWED CHAIR HOLDERSSince 1988, the endowed chair program at The Children’s Hospital of Philadelphia has been an essential part of our ability to attract and retain the most talented physicians and researchers. One of the highest scientific and academic honors, an endowed chair also represents one of the most meaningful and permanent forms of philanthropy.

ADOLESCENT MEDICINEOrton P. Jackson Endowed Chair in Adolescent MedicinePending appointment

ANESTHESIOLOGY AND CRITICAL CARE MEDICINEJames Battaglia Endowed Chair in Pediatric Pain ManagementGordon Barr, Ph.D.

The Children’s Hospital of Philadelphia Endowed Chair in Critical Care MedicineVinay M. Nadkarni, M.D.

John J. Downes, M.D., Endowed Chair in Pediatric Anesthesiology and Critical Care MedicineWilliam J. Greeley, M.D., M.B.A.

Russell C. Raphaely Endowed Chair in Critical Care MedicineRobert A. Berg, M.D.

Josephine J. Templeton Endowed Chair in Pediatric Anesthesiology Clinical EducationSusan C. Nicolson, M.D.

AUTISMRegional Autism Center Endowed ChairRobert T. Schultz, Ph.D.

CARDIOLOGYRobert and Dolores Harrington Endowed Chair in Pediatric CardiologyJack Rychik, M.D.

William J. Rashkind Endowed Chair in Pediatric CardiologyRobert J. Levy, M.D.

Evelyn Rome Tabas Endowed Chair in Pediatric CardiologyVictoria L. Vetter, M.D.

Jennifer Terker Endowed Chair in Pediatric CardiologyRobert E. Shaddy, M.D.

CARDIOTHORACIC SURGERYDaniel M. Tabas Endowed Chair in Pediatric Cardiothoracic SurgeryJ. William Gaynor, M.D.

Alice Langdon Warner Endowed Chair in Pediatric Cardiothoracic SurgeryThomas L. Spray, M.D.

CHILD AND ADOLESCENT PSYCHIATRYFrederick H. Allen Chair in Child PsychiatryTami D. Benton, M.D.

As of July 1, 2010

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CHILD DEVELOPMENT AND REHABILITATION MEDICINEHenry S. Cecil, M.D., Endowed Chair in Rehabilitative Medicine at Children’s Seashore HouseSusan E. Levy, M.D.

William T. Grant Endowed Chair in Child Development and RehabilitationMarc Yudkoff, M.D.

THE CHILDREN’S HOSPITAL OF PHILADELPHIA RESEARCH INSTITUTEEdmond F. Notebaert Endowed Chair in Pediatric ResearchPhilip R. Johnson Jr., M.D.

Mai and Harry F. West Endowed Chair in Pediatric ResearchThomas Curran, Ph.D.

EMERGENCY MEDICINENicholas Crognale Endowed Chair in Pediatric Emergency MedicineKathy N. Shaw, M.D.

ENDOCRINOLOGYLester Baker Endowed Chair in Pediatric DiabetesMichael A. Levine, M.D.

Daniel B. Burke Endowed Chair for Diabetes ResearchPending appointment

Thomas Moshang Endowed Chair in EndocrinologyPending appointment

GASTROENTEROLOGY AND NUTRITIONFred and Suzanne Biesecker Endowed Chair in Pediatric Liver DiseaseDavid A. Piccoli, M.D.

Colman Family Endowed Chair in Pediatric Inflammatory Bowel DiseaseRobert N. Baldassano, M.D.

Jean Cortner Endowed Chair in Pediatric GastroenterologyVirginia A. Stallings, M.D.

GENERAL PEDIATRICSThe Children’s Hospital of Philadelphia Endowed Chair in the Prevention of Child Abuse and NeglectCindy Christian, M.D.

David Cornfeld Endowed Chair in PediatricsRichard Rutstein, M.D.

Steven D. Handler Endowed Chair in Medical EthicsChris Feudtner, M.D., Ph.D., M.P.H.

John H. and Hortense Cassell Jensen Endowed Chair in Pediatric Development and TeachingStephen Ludwig, M.D.

Patrick S. Pasquariello Jr. Endowed Chair in General PediatricsLouis M. Bell, M.D.

Richard D. Wood Jr. and Jeanette A. Wood Endowed Chair in Pediatric Diagnostic Medicine Pending appointment

HEMATOLOGYBuck Family Endowed Chair in HematologyMonica Bessler, M.D., Ph.D.

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About CHOP

ENDOWED CHAIR HOLDERS

The Children’s Hospital of Philadelphia Endowed Chair in Pediatric HematologyMortimer Poncz, M.D.

Jane Fishman Grinberg Endowed Chair in Stem Cell ResearchMitchell J. Weiss, M.D.

Elias Schwartz, M.D., Endowed Chair in HematologyKim Smith-Whitley, M.D.

Frank E. Weise III Endowed Chair in Pediatric HematologyGerd Blobel, M.D., Ph.D.

HUMAN GENETICS AND MOLECULAR BIOLOGYLetitia B. and Alice Scott Endowed Chair in Human Genetics and Molecular BiologyElaine H. Zackai, M.D.

William Wikoff Smith Endowed Chair in Pediatric Genomic ResearchVivian Cheung, M.D.

Charles E.H. Upham Endowed Chair in Pediatric MedicineBeverly S. Emanuel, Ph.D.

IMMUNOLOGY AND INFECTIOUS DISEASESMaurice R. Hilleman Endowed Chair in VaccinologyPaul Offit, M.D.

Jeffrey Modell Endowed Chair in Pediatric Immunology ResearchJordan Orange, M.D., Ph.D.

Stanley Plotkin Endowed Chair in Pediatric Infectious DiseasesJeffrey M. Bergelson, M.D.

Frank R. Wallace Endowed Chair in Infectious DiseasesKathleen Sullivan, M.D., Ph.D.

INFORMATION TECHNOLOGYMildred L. Roeckle Endowed ChairBryan A. Wolf, M.D., Ph.D.

INTERNATIONAL ADOPTIONWawa Endowed Chair in International AdoptionSusan Friedman, M.D.

NEONATOLOGYGisela and Dennis Alter Endowed Chair in Pediatric NeonatologyHaralambos Ischiropoulos, Ph.D.

Werner and Gertrude Henle Endowed ChairPhyllis Dennery, M.D.

NEPHROLOGYLaffey-Connolly Endowed Chair in Pediatric NephrologySusan Furth, M.D.

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NEUROLOGYCatherine D. Brown Endowed Chair in Pediatric EpilepsyDennis Dlugos, M.D.

The Children’s Hospital of Philadelphia Endowed Chair in Pediatric NeurologyRobert R. Clancy, M.D.

Grace R. Loeb Endowed Chair in NeurosciencesGihan I. Tennekoon, M.D.

Hubert J.P. and Anne Faulkner Schoemaker Endowed Chair in Pediatric Neuro-OncologyPeter C. Phillips, M.D.

NURSINGRuth M. Colket Endowed Chair in Pediatric NursingBarbara Medoff-Cooper, Ph.D., R.N.

ONCOLOGYDavid Lawrence Altschuler Endowed Chair in Genomics and Computational BiologyPeter S. White, Ph.D.

Louis and Amelia Canuso Family Endowed Chair for Clinical Research in OncologyFrank M. Balis, M.D.

Giulio D’Angio Endowed Chair in Neuroblastoma ResearchJohn Maris, M.D.

Audrey E. Evans Endowed Chair in Pediatric OncologyGarrett M. Brodeur, M.D.

Joshua Kahan Endowed Chair in Pediatric LeukemiaPending appointment

Yetta Deitch Novotny Endowed Chair in Pediatric OncologyBeverly J. Lange, M.D.

Richard and Sheila Sanford Endowed Chair in Pediatric OncologyMichael D. Hogarty, M.D.

OPHTHALMOLOGYMabel E. Leslie Endowed Chair in Pediatric OphthalmologyMonte Mills, M.D.

ORTHOPAEDIC SURGERYRichard M. Armstrong Jr. Endowed Chair in Pediatric Orthopaedic SurgeryJohn P. Dormans, M.D.

Dr. Bong S. Lee Endowed Chair in Pediatric OrthopaedicsPending appointment

OTOLARYNGOLOGYThe Children’s Hospital of Philadelphia Endowed Chair in Pediatric OtolaryngologySteven D. Handler, M.D.

E. Mortimer Newlin Endowed Chair in Pediatric Otolaryngology and Human CommunicationRalph Wetmore, M.D.

William Potsic Endowed Chair in Pediatric Otolaryngology and Childhood CommunicationPending appointment

PATHOLOGYMichael and Charles Barnett Endowed Chair in Pediatric Mitochondrial Medicine and Metabolic DiseasesDouglas Wallace, Ph.D.

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About CHOP

ENDOWED CHAIR HOLDERSEvelyn Willing Bromley Endowed Chair in Clinical Laboratories and PathologyMichael J. Bennett, Ph.D.

Evelyn Willing Bromley Endowed Chair in Pathology and Clinical LaboratoriesJeffrey A. Golden, M.D.

Lucy Balian Rorke-Adams Endowed Chair in NeuropathologyPending appointment

Evelyn and George Willing Endowed Chair in Pathology ResearchJanis Burkhardt, Ph.D.

PEDIATRICSLeonard and Madlyn Abramson Endowed Chair in PediatricsAlan R. Cohen, M.D.

Mary D. Ames Endowed Chair in Child AdvocacyChristopher B. Forrest, M.D., Ph.D.

William H. Bennett Professor of Pediatrics at the University of Pennsylvania School of MedicineKatherine High, M.D.

PLASTIC AND RECONSTRUCTIVE SURGERYMary Downs Endowed Chair in Pediatric Craniofacial Treatment and ResearchRichard Kirschner, M.D.

Friends of Brian Endowed Chair in Pediatric Plastic and Reconstructive SurgeryPending appointment

Peter Randall Endowed Chair in Plastic and Reconstructive SurgeryScott P. Bartlett, M.D.

PULMONARY MEDICINERobert Gerard Morse Endowed Chair in Pediatric Pulmonary MedicineJulian Allen, M.D.

RADIOLOGYThe Children’s Hospital of Philadelphia Endowed Chair in Pediatric NeuroradiologyRobert Zimmerman, M.D.

The Children’s Hospital of Philadelphia Endowed Chair in Pediatric RadiologyJames S. Meyer, M.D.

Oberkircher Family Endowed Chair in Pediatric RadiologyTimothy Roberts, Ph.D.

William L. Van Alen Endowed Chair in Pediatric RadiologyDiego Jaramillo, M.D.

RHEUMATOLOGYJoseph Lee Hollander Endowed Chair in Pediatric RheumatologyTerri Finkel, M.D., Ph.D.

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SURGERYC. Everett Koop Endowed Chair in Pediatric SurgeryN. Scott Adzick, M.D., M.M.M.

Josephine J. and John M. Templeton Jr. Endowed Chair in Pediatric TraumaMichael L. Nance, M.D., F.A.A.P., F.A.C.S.

THORACIC AND FETAL SURGERYRuth M. and Tristram C. Colket, Jr. Endowed Chair in Pediatric SurgeryAlan W. Flake, M.D.

George Leib Harrison Endowed Chair in Fetal TherapyMark Paul Johnson, M.D.

UROLOGYLeonard and Madlyn Abramson Endowed Chair in Pediatric UrologyDouglas A. Canning, M.D.

John W. Duckett Jr. Endowed Chair in Pediatric UrologyPending appointment

Howard M. Snyder III Endowed Chair in Pediatric UrologyPending appointment

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About CHOP

CREDITSThe Annual Report is produced by the Marketing and Public Relations Department and the Web Center of The Children’s Hospital of Philadelphia

Stephanie HogarthChief Marketing Officerhogarths@email.chop.edu

Linda LightnerCreative Directorlightner@email.chop.edu

David McIntoshArt Directormcintoshd@email.chop.edu

Zan HaleManaging Editorhalez@email.chop.edu

Sara BartonSenior Writerbartonsa@email.chop.edu

Abny SanticolaSenior Writersanticolaa@email.chop.edu

Jessa StephensSenior Writerstephensj@email.chop.edu

Julie SloaneSenior Writer, Developmentsloanej@email.chop.edu

Natasha MurphySenior Account Managermurphyna@email.chop.edu

Sandra GravineseProduction Managergravinese@email.chop.edu

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Denise AmbronTraffic Managerambron@email.chop.edu

Dario MesciaArt Directormescia@email.chop.edu

Stephen CrawfordInteractive Designercrawfords@email.chop.edu

Corey EverettSenior Interactive Designereverett@email.chop.edu

Brian PomeroySenior Solutions Consultantpomeroy@email.chop.edu

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Paul Crane, Javier MitchellContributing Photography

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©2011 The Children’s Hospital of Philadelphia, All Rights Reserved.

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About The Children’s Hospital of PhiladelphiaAs the nation’s first hospital devoted exclusively to caring for children, The Children’s Hospital of Philadelphia has been the birthplace of many dramatic firsts in pediatric medicine since 1855. The Hospital has fostered medical discoveries and innovations that have improved pediatric healthcare and saved countless children’s lives.

Fast Forward reflects CHOP’s never-ending efforts to make the next great advances in pediatric healthcare as rapidly and safely as possible. With the help of our philanthropic partners, our exceptionally skilled, compassionate team continues to deliver on our promise of better health for today’s — and tomorrow’s — children.

Best in the United StatesThe Children’s Hospital of Philadelphia is ranked the best pediatric hospital in the United States by Parents magazine. Children’s Hospital is also one of only eight pediatric hospitals nationwide named to U.S.News & World Report’s prestigious 2010 – 11 Honor Roll.

Read this report online at www.chop.edu/ar