2004-2005 pharmacology review of everything (principles, cardiovascular and respiratory drugs have...
DESCRIPTION
Spironolactone Potassium sparing diuretic Antiandrogen Aldosterone receptor antagonist Androgen receptor antagonist Testosterone synthesis inhibitor Antihypertensive Heart failure treatmentTRANSCRIPT
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2004-2005Pharmacology Review
of Everything(Principles, Cardiovascular and Respiratory drugs have been
updated)
May 4, 202311:11 PM
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Spectinomycin
AntibioticBacteriostatic protein synthesis
inhibitor
30S ribosome
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Spironolactone
Potassium sparing diureticAntiandrogen
Aldosterone receptor antagonistAndrogen receptor antagonist
Testosterone synthesis inhibitorAntihypertensive
Heart failure treatment
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St. John’s Wort
Dietary supplement
Antidepressant
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Streptokinase
Thrombolytic
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Streptomycin
Aminoglycoside antibioticBactericidal protein synthesis
inhibitor
30S ribosomeFreezes initiation
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Succinylcholine
Paralytic
Depolarizing blockerParalyzes skeletal muscles
Bronchoconstrictor
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Sucralfate
Antiulcer
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Sufentanil
OpioidGeneral anaesthetic
Intravenous anaesthetic
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Sulfacetamide
Sulfonamide antibioticMicrobial nucleic acid
and protein synthesis inhibitor
Inhibits dihydropteroate synthetaseTopical
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Sulfadoxine
Sulfonamide antibioticMicrobial nucleic acid
and protein synthesis inhibitor
Dihydropteroate synthetase inhibitor
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Sulfamethoxazole
Sulfonamide antibioticMicrobial nucleic acid
and protein synthesis inhibitor
Inhibits dihydropteroate synthetase
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Sulfasalazine
Disease modifyinganti-rheumatic drug (DMARD)
Metabolized to sulfonamide+ salicylate (NSAID)
Treatment of IBD
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Sulfinpyrazone
Uricosuric
Anti-gout
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Sulfisoxazole
Sulfonamide antibioticNucleic acid and
protein synthesis inhibitor
Inhibits dihydropteroate synthetase
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Sulfonamides
AntibioticsNucleic acid and
protein synthesis inhibitors
Inhibit dihydropteroate synthetase
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Sulindac
NSAIDAnalgesic, Anti-inflammatory,
Antipyretic
Cyclooxygenase inhibitor
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Suramin
Tropical antiparasitic
Treatment of African Trypanosomiasis
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Tacrolimus
ImmunosuppressiveAntineoplastic
Binds FKBP (FK506 binding protein)
Inhibits calcineurin
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Tamoxifen
Antineoplastic Antiestrogen
Estrogen receptor anatagonist
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Tegaserod
IBS treatment
5HT4 receptor agonist
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Telmisartan
Antihypertensive
Angiotensin receptor blocker(ARB)
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Temazepam
Sedative/Hypnotic
Benzodiazepine Acts on GABAA receptor
complex
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Tenecteplase
Thrombolytic
Tissue plasminogen activator (tPA)
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Terazosin
Sympatholytic1 adrenergic antagonist
AntihypertensiveTreatment for benign prostatic
hypertrophy
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Terbinafine
Allylamine antifungal
Inhibits ergosterol synthesis by inhibiting squalene epoxidase
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Terbutaline
Sympathomimetic2 adrenergic agonist
Short acting bronchodilator Tocolytic
Uterine relaxant
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Testosterone
Androgen
Natural male gonadal steroid
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Testosterone cypionate
Androgen
Synthetic depot
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Testosterone enanthate
Androgen
Synthetic depot
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Testosterone propionate
Androgen
Synthetic depot
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Tetracaine
Local anaesthetic
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Tetracycline
AntibioticBacteriostatic protein synthesis
inhibitor Antiulcer
30S ribosomePrevents aminoacyl tRNA attachment
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Thalidomide
AntineoplasticLeprosy treatment
Anti-angiogenicAnti-TNF
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Theophylline
Bronchodilator
MethylxanthinePhosphodiesterase inhibitor
Used in asthma
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Thiabendazole
Antihelminthic
Treatment of intestinal roundworms
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6-Thioguanine
Antineoplastic
Antimetabolite (“pseudofeedback inhibition” of
HGPRT and PRP – purine synthesis)
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Thiopental
General Anaesthetic
Ultra-short-acting barbiturate
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Thioridazine
Antipsychotic
Phenothiazine
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Thiotepa
Antineoplastic
Alkylating agent
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Thiothixene
Antipsychotic
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Thrombopoietin
Cytokine
Platelet synthesis stimulator
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Thromboxane A2 (TXA2)
Autacoid
Promotes platelet aggregation Cyclooxygenase product of arachidonate metabolism
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Thyrotropin-releasing Hormone (TRH)
Hypothalamic hormone
Stimulates release of thyroid stimulating hormone (TSH) from
the anterior pituitary
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ThyrotropinThyroid-stimulating Hormone
(TSH)
Anterior pituitary hormone
Stimulates production of thyroxine (T4), triiodothyronine
(T3) and thyroglobulin
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Ticarcillin
Penicillin antibioticCell wall synthesis inhibitor
Anti-pseudomonal penicillinInhibits peptidoglycan cross-
linking
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Ticlopidine
Antiplatelet
ADP receptor antagonist
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Timolol
Sympatholytic adrenergic antagonist
AntihypertensiveGlaucoma treatment
Anti-anginalBronchoconstrictor
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Tissue plasminogen activators
Thrombolytics
alteplase, reteplase, tenecteplase
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Tobramycin
Aminoglycoside antibioticBactericidal protein synthesis
inhibitor
30S ribosomeFreezes initiation
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Tocainide
Class I antiarrhythmic
Na+ channel blocker(activated channels)
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Tolbutamide
Oral hypoglycemic
SulfonylureaInsulinotropic
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Tolterodine
Anticholinergic
Muscarinic receptor antagonistPrevents urination
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Toremifene
Estrogen antagonist
Selective estrogen receptor modulator (SERM)
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Tosemide
Loop diuretic
Na-K-2Cl symporter inhibitor
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Trandopril
Antihypertensive
Converting enzyme inhibitor
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Tranylcypromine
Antidepressant
Monoamine oxidase inhibitor (MAO-I)
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Trastuzumab
Antineoplastic
Anti-HER2 antibody
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Triamcinolone
AdrenocorticosteroidGlucocorticoid
Anti-inflammatory steroidInhaled
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Triamterene
Potassium sparing diuretic
Sodium channel inhibitorAntihypertensive
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Triazolam
Sedative/Hypnotic
Benzodiazepine Acts on GABAA receptor
complex
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Trifluoperazine
Antipsychotic
Phenothiazine
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Trifluridine
Antiherpes
Pyrimidine analogPhosphorylated to inhibitor of
viral DNA polymerase
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Trihexyphenidyl
Antiparkinson
Antimuscarinic
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Trimethaphan
SympatholyticAnticholinergic
Nicotinic antagonistAntihypertensive
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Trimethoprim
AntibioticProtein and nucleic acid
synthesis inhibitor
Inhibits bacterial dihydrofolate reductase
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Tripelennamine
Classical antihistamine
H1 antagonist
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Tubocurarine
Paralytic
Paralyzes skeletal muscles
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Tumor necrosis factor
CytokineAntineoplastic
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Tyramine
Indirect sympathomimetic
VasoconstrictorVasopressor
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Ultralente insulin
HormoneInsulin analogue
Long acting
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Urokinase
Thrombolytic
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Valacyclovir
Antiherpes
Purine analogPhosphorylated to inhibitor of
viral DNA polymerase
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Valsartan
Antihypertensive
Angiotensin receptor blocker(ARB)
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Valganciclovir
Antiherpes
Purine analogPhosphorylated to inhibitor of
viral DNA polymerase
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Valproic acid
Anticonvulsant
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Valsartan
Antihypertensive
Angiotensin receptor blocker(ARB)
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Vancomycin
AntibioticInhibits cell wall synthesis
Not a lactam
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Arginine vasopressin(Antidiuretic hormone;
ADH)
Hypothalamic (posterior pituitary) hormone
AntidiureticVasoconstrictor
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Vecuronium
Paralytic
Paralyze skeletal muscles
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Verapamil
Class IV antiarrhythmicAntihypertensive
L-type Ca2+ channel blocker Antianginal
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Vigabatrin
Anticonvulsant
Irreversible GABA aminotransferase inhibitor
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Vinblastine
Antineoplastic
Vinca alkaloidNatural product
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Vincristine
Antineoplastic
Vinca alkaloidNatural product
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Voriconazole
Triazole antifungal
Inhibits synthesis of ergosterol by inhibiting lanosterol 14
demethylase
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Warfarin
Anticoagulant
Vitamin K synthesis inhibitor
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Zafirlukast
Leukotriene inhibitor
LTR1 and LTD4 antagonistAsthma treatment
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Zalcitabine
Antiretroviral
Nucleoside reverse transcriptase inhibitor (NRTI)
Dideoxycytidine (ddC)
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Zanamivir
Antiviral
Inhibits neuraminidaseand decreases viral release
Treatment of Influenza A & B
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Zidovudine
Antiretroviral
Nucleoside reverse transcriptase inhibitor (NRTI)
Azidothymidine (AZT)
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Zileuton
Leukotriene inhibitor
5-lipoxygenase inhibitorUsed in asthma
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Zolpidem
Sedative/Hypnotic
Non-benzodiazepine