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Caroline Martin 127 Shirley Ave. Williamsburg, VA 23185 Phone: (703) 772-3052 E-Mail: [email protected] 1 Education B.S. (expected 2017) Biology GPA: 3.81 College of William & Mary (W&M), Williamsburg, VA. Technical Skills Neuroscience and Molecular Genetics Rapid Prototyping Electrophysiology: single-cell patch clamp recording, Patchmaster software, and LabChart software Next generation sequencing: familiarity with SMART-Seq v4 Ultra Low Input RNA Kit Recombinant DNA methods: plasmid purification, mammalian cell transfection, PCR, and restriction enzyme digestion Mammalian tissue culture Neuroanatomy: Immunohistochemistry on mammalian neuronal and astrocytic tissues and hydrogel-based tissue clearing Confocal microscopy: Nikon A1R laser-scanning confocal microscope and ImageJ software Transgenic animal husbandry: two years experience working with cre-lox recombinase- based animal models Computer aided design (CAD) software: AutoDesk Inventor, Fusion Makerbot 3D printing Computer numeric control (CNC) routing Arduino programming Other Science writing: lead science writer for W&M newspaper, The Flat Hat Science instruction: math and science tutor at Tribe Tutorzone, 2014-present Microsoft Office suite: Excel, Powerpoint, and Word Adobe Creative suite: Illustrator, Photoshop Research Training and Experience 2016 Undergraduate Trainee, 01-05/2016. Advisor: Matthew Kelley, Ph.D. – National Institute on Deafness and other Communication Disorders (NIDCD), National Institutes of Health (NIH). Studied cochlear development and gained experience with molecular genetics techniques. 2015 Undergraduate Researcher, 01/2015-present. Advisor: Christopher A. Del Negro, Ph.D. – Integrated Science Center, College of William & Mary. Investigated interneurons whose precursors express the homeobox transcription factor Dbx1, which putatively drive inspiratory breathing movements. 2013 Undergraduate Researcher, 08/2013-12/2014. Advisor: Mark Forsyth, Ph.D. – Integrated Science Center, College of William & Mary. Investigated molecular signaling pathways in the cancer- and ulcer-causing bacteria H. pylori. Submitted Abstract 2016 A. Kottick, C.A. Martin, and C.A. Del Negro. Labeling Dbx1 neurons and glia in the preBötzinger Complex based on the timing and dose of tamoxifen administration in inducible Dbx1 Cre-driver transgenic mice. eNeuro (eN-NWR-0305-16). Submitted on 10/23/2016.

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Page 1: 170101_CV

Caroline Martin 127 Shirley Ave.� Williamsburg, VA 23185

Phone: (703) 772-3052 � E-Mail: [email protected]

1

Education

B.S. (expected 2017) Biology

GPA: 3.81

College of William & Mary (W&M), Williamsburg, VA.

Technical Skills Neuroscience and Molecular Genetics Rapid Prototyping

• Electrophysiology: single-cell patch clamprecording, Patchmaster software, and LabChartsoftware

• Next generation sequencing: familiarity withSMART-Seq v4 Ultra Low Input RNA Kit

• Recombinant DNA methods: plasmidpurification, mammalian cell transfection, PCR,and restriction enzyme digestion

• Mammalian tissue culture

• Neuroanatomy: Immunohistochemistry onmammalian neuronal and astrocytic tissues andhydrogel-based tissue clearing

• Confocal microscopy: Nikon A1R laser-scanningconfocal microscope and ImageJ software

• Transgenic animal husbandry: two yearsexperience working with cre-lox recombinase-based animal models

• Computer aided design (CAD)software: AutoDesk Inventor,Fusion

• Makerbot 3D printing

• Computer numeric control (CNC)routing

• Arduino programming

Other

• Science writing: lead sciencewriter for W&M newspaper, TheFlat Hat

• Science instruction: math andscience tutor at Tribe Tutorzone,2014-present

• Microsoft Office suite: Excel,Powerpoint, and Word

• Adobe Creative suite: Illustrator,Photoshop

Research Training and Experience 2016 Undergraduate Trainee, 01-05/2016. Advisor: Matthew Kelley, Ph.D. – National Institute on Deafness

and other Communication Disorders (NIDCD), National Institutes of Health (NIH). Studied cochlear development and gained experience with molecular genetics techniques.

2015 Undergraduate Researcher, 01/2015-present. Advisor: Christopher A. Del Negro, Ph.D. – IntegratedScience Center, College of William & Mary. Investigated interneurons whose precursors express the homeobox transcription factor Dbx1, which putatively drive inspiratory breathing movements.

2013 Undergraduate Researcher, 08/2013-12/2014. Advisor: Mark Forsyth, Ph.D. – Integrated ScienceCenter, College of William & Mary. Investigated molecular signaling pathways in the cancer- and ulcer-causing bacteria H. pylori.

Submitted Abstract

2016 A. Kottick, C.A. Martin, and C.A. Del Negro. Labeling Dbx1 neurons and glia in the preBötzingerComplex based on the timing and dose of tamoxifen administration in inducible Dbx1 Cre-driver transgenic mice. eNeuro (eN-NWR-0305-16). Submitted on 10/23/2016.

Page 2: 170101_CV

Caroline Martin 127 Shirley Ave.� Williamsburg, VA 23185

Phone: (703) 772-3052 � E-Mail: [email protected]

2

Intramural Presentations

2016 C.A. Martin, A. Kottick, and C.A. Del Negro. Labeling Dbx1 neurons and glia in the preBötzinger Complex based on the timing and dose of tamoxifen administration in inducible Dbx1 Cre-driver transgenic mice. Poster presentation. W&M Summer Research Symposium, College of William & Mary, Williamsburg, VA, Oct. 2, 2016.

2016 C.A. Martin, J. Mays, M. Kelly, K. Ellis, and M. Kelley. Characterizing the genetic basis for a medial/lateral border in the mammalian cochlea. Poster presentation. NIDCD Retreat 2016, Washington, D.C April 29, 2016.

Extramural Presentations

2016 C.A. Martin, A. Kottick, and C.A. Del Negro. Labeling Dbx1 neurons and glia in the preBötzinger Complex based on the timing and dose of tamoxifen administration in inducible Dbx1 Cre-driver transgenic mice. Poster presentation (215.08 / F34). Society for Neuroscience presentation 215.08 / F34, San Diego, CA, November 13, 2016.

2016 C.A. Martin, A. Kottick, C.A. Del Negro. Labeling Dbx1 neurons and glia in the preBötzinger Complex based on the timing and dose of tamoxifen administration in inducible Dbx1 Cre-driver transgenic mice. Poster presentation (FENS-2867). Federation of European Neuroscience Societies (FENS) Forum 2016, Copenhagen, Denmark, July 3, 2016.

2016 M. Kelly (presenter), J. Burns, K. Ellis, J. Mays, C.A. Martin, R. Morell, M. Kelley. Investigating the development of cochlear lateral supporting cell subtypes by single cell mRNA-seq. Poster presentation (PS 797). Association for Research in Otolaryngology MidWinter Meeting 2016, San Diego, CA February 20-24, 2016.

Work Experience

2016

Coordinator, 04/2016 – present. Small Hall Makerspace, College of William & Mary. Maintains and supervises the rapid prototyping equipment housed in this facility. Promotes campus awareness of this resource. Conducts near-daily tours and tutorials, as well as larger outreach events. Serves on the Makerspace User Board and peer-reviews grant proposals submitted by students.

2014 Tutor, 06/2014 – present. Tribe TutorZone, College of William & Mary. Tutored students in biology, calculus, and chemistry.

2012 Explainer, 02/2012 – 04/2016. National Air and Space Museum, 600 Independence Ave SW, Washington, DC 20560. Carried out educational programs for young visitors at the museum. Conducted hands-on demonstrations, presentations in the observatory, and entry-level science experiments. Contributed to the program's online help center, “Ask an Explainer.”

Honors and Awards

04/2016 William & Mary Honors Research Fellowship ($6,000)

08/2013-present Dean’s List

02/2016 Roy R. Charles Center Student Research Grant ($3,000)

12/2015 Vice Provost Grant ($500)

03/2015 Tri Delta Academic Scholarship ($1,000)