1.1 introduction to cells ib biology hl 1 mrs. peters fall 2014
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1.1 Introduction to Cells1.1 Introduction to Cells
IB Biology HL 1IB Biology HL 1
Mrs. PetersMrs. Peters
Fall 2014Fall 2014
What is a Cell?What is a Cell?
CellCell: the basic structural : the basic structural and functional unit of all and functional unit of all organismsorganisms
CellsCells Discovered by Robert Discovered by Robert
Hooke in the late 1600Hooke in the late 1600’’ss Examined a piece of cork Examined a piece of cork
with a home-made with a home-made microscopemicroscope
Saw numerous box-shaped Saw numerous box-shaped structuresstructures
Named them Named them ““cellscells”” after the after the rooms or cells that Monks rooms or cells that Monks lived inlived in
www.history-of-the-microscope.org, ucmp.berkeley.edu
U1. Cell TheoryU1. Cell Theory
The Cell TheoryThe Cell Theory: : When Schleiden and When Schleiden and Schwann proposed the cell theory in 1838, Schwann proposed the cell theory in 1838, cell biology research was forever changed. cell biology research was forever changed. Schleiden was a botanist (studied plants)Schleiden was a botanist (studied plants) Schwann was a zoologist (studied animals)Schwann was a zoologist (studied animals) Shared notes and came up with the theory Shared notes and came up with the theory
together.together. The cell theory also provides us with an The cell theory also provides us with an
operational definition of "life."operational definition of "life."
U1. Cell TheoryU1. Cell Theory
The cell theory states that: The cell theory states that: All life forms are made from one or more All life forms are made from one or more
cells. cells. Cells only arise from pre-existing cells. Cells only arise from pre-existing cells. The cell is the smallest form of life.The cell is the smallest form of life.
Evidence for Cell TheoryEvidence for Cell Theory
All life forms are made from one or All life forms are made from one or more cells.more cells.
Evidence:Evidence: since Robert Hooke, tissue since Robert Hooke, tissue samples for many different organisms samples for many different organisms have been examined using light and have been examined using light and electron microscopes and have been electron microscopes and have been found to consist of cells.found to consist of cells.
Evidence for Cell TheoryEvidence for Cell TheoryCells only arise from pre-existing cells.Cells only arise from pre-existing cells.
Evidence:Evidence: Louis Pasteur’s experiments in the Louis Pasteur’s experiments in the 1800’s1800’s
Education-portal.com
Evidence for Cell TheoryEvidence for Cell Theory
The cell is the smallest form of life.The cell is the smallest form of life.
Evidence: Evidence: experiments can be done in experiments can be done in which cells are burst open and the which cells are burst open and the subunits (organelles) are separated subunits (organelles) are separated using a centrifuge, the subunits of cells using a centrifuge, the subunits of cells do not survive long by themselves.do not survive long by themselves.
A1. Atypical to Cell TheoryA1. Atypical to Cell Theory
Striated muscles: Striated muscles: skeletal muscles which skeletal muscles which are made up of muscle fibers that are are made up of muscle fibers that are longer than a “normal” cell and contain longer than a “normal” cell and contain several hundred nucleiseveral hundred nuclei
www.physioweb.org
A1. Atypical to Cell TheoryA1. Atypical to Cell Theory
Mammalian red blood cells (erythrocytes)Mammalian red blood cells (erythrocytes) Mature blood cells do not contain a nucleusMature blood cells do not contain a nucleus
Macroevolution.net
A1. Atypical to Cell TheoryA1. Atypical to Cell Theory
Giant algae: Giant algae: single cells that are single cells that are undifferentiated which are attached to undifferentiated which are attached to chains of identical cells or surrounded by chains of identical cells or surrounded by an outer layer that allows them to form an outer layer that allows them to form large structureslarge structures
Oceana.org
A1. Atypical to Cell TheoryA1. Atypical to Cell Theory
Aseptate fungal Aseptate fungal hyphae: hyphae: long threads long threads on fungi which have on fungi which have many nuclei but are many nuclei but are not divided into not divided into separate cells by cell separate cells by cell wallswalls
Peer.tamu.edu, psmicrographs.co.uk
U2. Living ThingsU2. Living Things Living organisms can be Living organisms can be multicellularmulticellular (many (many
cells) or cells) or unicellularunicellular (one cell) (one cell)
All living things need the following functions All living things need the following functions to survive:to survive: Metabolism, growth, response to environment, Metabolism, growth, response to environment,
homeostasis, nutrition, excretion, and homeostasis, nutrition, excretion, and reproductionreproduction
U2. Living ThingsU2. Living Things Which of the following do you think is Which of the following do you think is
considered non-living based on cell theory considered non-living based on cell theory and the needs of living things? Why?and the needs of living things? Why?
A. bacteriaA. bacteria B. planktonB. plankton C. virusesC. viruses
U2. Living ThingsU2. Living Things
Answer:Answer: Viruses because they are not made up of Viruses because they are not made up of
cellscells They reproduce by inserting their DNA into They reproduce by inserting their DNA into
the DNA of another organism.the DNA of another organism. Cells become little virus producing factories.Cells become little virus producing factories.
Aids Viruswww.healthoma.com
Influenza Viruswww.dreamstime.com
U2. Functions of Living ThingsU2. Functions of Living Things
Metabolism: Metabolism: the break down of organic the break down of organic material to make chemicals needed to material to make chemicals needed to sustain lifesustain life
Growth: Growth: ability to grow and develop in ability to grow and develop in different stages (ex: infant to child to adult)different stages (ex: infant to child to adult)
Response to environment: Response to environment: ability to ability to detect change in surroundings and detect change in surroundings and respond accordingly to surviverespond accordingly to survive
U2. Functions of Living ThingsU2. Functions of Living Things
Homeostasis: Homeostasis: the ability to control its the ability to control its internal environment (this is why you internal environment (this is why you sweat or shiver)sweat or shiver)
Nutrition: Nutrition: must be able to obtain food must be able to obtain food either by producing its own or consuming either by producing its own or consuming other thingsother things
U2. Functions of Living ThingsU2. Functions of Living Things
Excretion:Excretion: the ability to dispose of waste the ability to dispose of waste created from metabolismcreated from metabolism
Reproduction: Reproduction: survival depends on survival depends on creating offspring either sexually or creating offspring either sexually or asexuallyasexually
TOK DiscussionTOK Discussion
There is a difference between the living There is a difference between the living and non-living environment.and non-living environment.
How are we able to know the difference?How are we able to know the difference?
U3. Surface Area to Volume RatioU3. Surface Area to Volume Ratio Cells are very small, the size of the Cells are very small, the size of the
organism does not change the size of cellsorganism does not change the size of cells Elephant cells are the same size as mouse Elephant cells are the same size as mouse
cellscells
U3. Surface Area to Volume RatioU3. Surface Area to Volume Ratio
The The volumevolume of a cell determines the of a cell determines the level level of metabolic activityof metabolic activity that takes place in it that takes place in it
The The surface area surface area of a cell determines the of a cell determines the rate of exchange of materials rate of exchange of materials with the with the outside environmentoutside environment
U3. Surface Area to Volume RatioU3. Surface Area to Volume Ratio As volume increases, so does surface As volume increases, so does surface
area, but not proportionatelyarea, but not proportionately
If a cell is cube shaped, letIf a cell is cube shaped, let’’s see what s see what happens as the cube changes sizehappens as the cube changes size SA = surface areaSA = surface area Vol = volumeVol = volume
U3. Surface Area to Volume RatioU3. Surface Area to Volume Ratio
Side (mm) SA (mm2) Vol (mm3) Ratio SA to Vol
1 6 1 6:1
2 24 8 3:1
3 54 27 2:1
The overall ratio gets smaller as cells increase in size.
Surface Area to Volume RatioSurface Area to Volume Ratio
As a cell grows larger, it has less surface As a cell grows larger, it has less surface area to obtain materials and the rate of area to obtain materials and the rate of exchange becomes limiting; the cell canexchange becomes limiting; the cell can’’t t keep up with its requirementskeep up with its requirements
Surface Area to Volume RatioSurface Area to Volume Ratio
Cells with thin projections or folds (microvilli) Cells with thin projections or folds (microvilli) on their surface, increase surface area on their surface, increase surface area without increasing volumewithout increasing volume
Larger organisms donLarger organisms don’’t have larger cells, t have larger cells, they have more cellsthey have more cells
Surface Area to Volume RatioSurface Area to Volume Ratio
Cell size is limited by surface area to Cell size is limited by surface area to volume ratiovolume ratio The smaller the cell, the higher the surface The smaller the cell, the higher the surface
area to volume ratioarea to volume ratio High surface area to volume ratio facilitates High surface area to volume ratio facilitates
the exchange of materials between the cell the exchange of materials between the cell and its environment more quicklyand its environment more quickly
Cell SizeCell Size Most cells are too small to see Most cells are too small to see
with the naked eye; light and with the naked eye; light and electron microscopes are electron microscopes are needed to see themneeded to see them
Virtual Field Trip Time!Virtual Field Trip Time! Write down relative size Write down relative size
comparisons for atoms, comparisons for atoms, molecules, bacteria, organelles, molecules, bacteria, organelles, eukaryotes (must use correct eukaryotes (must use correct units)units)
Membrane thickness is ~7nmMembrane thickness is ~7nm
Relative Size ReviewRelative Size ReviewInvisible: Invisible: • 0.04 nm Atom0.04 nm Atom• 0.05-1 nm small molecules0.05-1 nm small molecules• 1.2-2 nm large molecules1.2-2 nm large molecules
Visible with electron microscope:Visible with electron microscope:• 7nm Cell Membrane Thickness7nm Cell Membrane Thickness• 50-90 nm Viruses50-90 nm Viruses
Relative Size ReviewRelative Size Review
Visible with light microscope:Visible with light microscope:• 0.5-1 µm Bacteria0.5-1 µm Bacteria• 20 nm-1 µm Organelles20 nm-1 µm Organelles• 20 µm Animal cell20 µm Animal cell• 40 µm Plant cell40 µm Plant cell
U4. Emergent PropertiesU4. Emergent Properties
Emergent properties/characteristics are Emergent properties/characteristics are Properties that arise from the interaction of Properties that arise from the interaction of component partscomponent parts
Different cell types interact with each other Different cell types interact with each other to allow more complex functions to take to allow more complex functions to take placeplace
Ex: nerve cells interact with muscle cells to Ex: nerve cells interact with muscle cells to stimulate movementstimulate movement
tissuestissues
Main Types of CellsMain Types of Cells
Two main types of cells determined by Two main types of cells determined by structurestructure Prokaryotes Prokaryotes
• Greek meaning Greek meaning ““before the nucleusbefore the nucleus”” EukaryotesEukaryotes
• Cells that have a nucleusCells that have a nucleus
ProkaryotesProkaryotes General Characteristics:General Characteristics:
UnicellularUnicellular No membrane bound No membrane bound
organellesorganelles No true nucleusNo true nucleus
Types:Types: BacteriaBacteria
• Spirals, rods, spheresSpirals, rods, spheres
EukaryotesEukaryotes General Characteristics:General Characteristics:
Unicellular or multicellularUnicellular or multicellular Membrane bound Membrane bound
Organelles Organelles True NucleusTrue Nucleus
Types:Types: PlantPlant AnimalAnimal Fungi (donFungi (don’’t need to t need to
worry about this one!)worry about this one!)
Microscopes Part 2Microscopes Part 2
Draw the following from Prepared Slides:Draw the following from Prepared Slides: Paramecium Paramecium Three types of bacteriaThree types of bacteria Frog BloodFrog Blood SpirogyraSpirogyra
Start a new paper for this set of drawings, Start a new paper for this set of drawings, remember:remember:• Use pencil or colored pencilsUse pencil or colored pencils• Fill the boxFill the box• Label the box (what and magnification)Label the box (what and magnification)
Surface Area to Volume RatioSurface Area to Volume Ratio
Time to create!Time to create! Obtain a piece of clay and directionsObtain a piece of clay and directions Make each shape and record the surface area Make each shape and record the surface area
and volume ratiosand volume ratios Compare surface area and volume for each Compare surface area and volume for each
shapeshape