1 trancatheter aortic valve implantation (tavi) georgios i. papaioannou, md, mph, facc, fscai...

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1 Trancatheter Aortic Valve Implantation (TAVI) Georgios I. Papaioannou, MD, MPH, FACC, FSCAI Director, Interventional Cardiologist Athens Medical Center Cardiac Catheterization Laboratory 4/3/2015 www.epemvatikikardiol gia.gr

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Page 1: 1 Trancatheter Aortic Valve Implantation (TAVI) Georgios I. Papaioannou, MD, MPH, FACC, FSCAI Director, Interventional Cardiologist Athens Medical Center

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Trancatheter Aortic Valve Implantation

(TAVI)

Georgios I. Papaioannou, MD, MPH, FACC, FSCAI

Director, Interventional Cardiologist

Athens Medical Center

Cardiac Catheterization Laboratory

4/3/2015

www.epemvatikikardiolgia.gr

Page 2: 1 Trancatheter Aortic Valve Implantation (TAVI) Georgios I. Papaioannou, MD, MPH, FACC, FSCAI Director, Interventional Cardiologist Athens Medical Center

Aortic Valve Anatomy

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Page 3: 1 Trancatheter Aortic Valve Implantation (TAVI) Georgios I. Papaioannou, MD, MPH, FACC, FSCAI Director, Interventional Cardiologist Athens Medical Center

Aortic Root Anatomy

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Page 4: 1 Trancatheter Aortic Valve Implantation (TAVI) Georgios I. Papaioannou, MD, MPH, FACC, FSCAI Director, Interventional Cardiologist Athens Medical Center

Causes of Aortic Stenosis

• Age related-Annular Calcification• History of Rheumatic Fever• Congenital Anomalies (Bicuspid Valve)• History of Chest Radiation• Autoimmune Diseases• Congenital Hypercholesterolemia• End-stage Renal Disease

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Page 5: 1 Trancatheter Aortic Valve Implantation (TAVI) Georgios I. Papaioannou, MD, MPH, FACC, FSCAI Director, Interventional Cardiologist Athens Medical Center

Incidence of Aortic and Mitral Valve Disease

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Page 6: 1 Trancatheter Aortic Valve Implantation (TAVI) Georgios I. Papaioannou, MD, MPH, FACC, FSCAI Director, Interventional Cardiologist Athens Medical Center

Natural History and Symptoms of Aortic Stenosis

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Page 7: 1 Trancatheter Aortic Valve Implantation (TAVI) Georgios I. Papaioannou, MD, MPH, FACC, FSCAI Director, Interventional Cardiologist Athens Medical Center

Aortic Stenosis Treatment Algorithm

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Page 8: 1 Trancatheter Aortic Valve Implantation (TAVI) Georgios I. Papaioannou, MD, MPH, FACC, FSCAI Director, Interventional Cardiologist Athens Medical Center

Choice of Surgival or Transcatheter Treatment of AS

Recommendations Class LOE

Surgical AVR in low or intermediate risk patients

I A

TAVI or high-risk Surgery should be performed under Heart Team Guidance

I C

TAVI for extremely high-risk patients + post TAVI predicted survival > 12 months

I B

TAVI alternative to SAVR for high-risk patients IIa B

BAV as a bridge to TAVI or SAVR IIb C

TAVI not recommended in patients with comorbidities which preclude benefit

III B

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Page 9: 1 Trancatheter Aortic Valve Implantation (TAVI) Georgios I. Papaioannou, MD, MPH, FACC, FSCAI Director, Interventional Cardiologist Athens Medical Center

PARTNER 1A-2 year Results

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Page 10: 1 Trancatheter Aortic Valve Implantation (TAVI) Georgios I. Papaioannou, MD, MPH, FACC, FSCAI Director, Interventional Cardiologist Athens Medical Center

PARTNER 1B-Extremely High Risk Pts

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Page 11: 1 Trancatheter Aortic Valve Implantation (TAVI) Georgios I. Papaioannou, MD, MPH, FACC, FSCAI Director, Interventional Cardiologist Athens Medical Center

US CoreValve Trial

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Page 12: 1 Trancatheter Aortic Valve Implantation (TAVI) Georgios I. Papaioannou, MD, MPH, FACC, FSCAI Director, Interventional Cardiologist Athens Medical Center

US CoreValve Trial

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Page 13: 1 Trancatheter Aortic Valve Implantation (TAVI) Georgios I. Papaioannou, MD, MPH, FACC, FSCAI Director, Interventional Cardiologist Athens Medical Center

US CoreValve Trial-Complications

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Page 14: 1 Trancatheter Aortic Valve Implantation (TAVI) Georgios I. Papaioannou, MD, MPH, FACC, FSCAI Director, Interventional Cardiologist Athens Medical Center

TAVI Candidates

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Page 15: 1 Trancatheter Aortic Valve Implantation (TAVI) Georgios I. Papaioannou, MD, MPH, FACC, FSCAI Director, Interventional Cardiologist Athens Medical Center

Worldwide TAVI Candidates

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Page 16: 1 Trancatheter Aortic Valve Implantation (TAVI) Georgios I. Papaioannou, MD, MPH, FACC, FSCAI Director, Interventional Cardiologist Athens Medical Center

Wordwide TAVI Incidence Candidates

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Page 17: 1 Trancatheter Aortic Valve Implantation (TAVI) Georgios I. Papaioannou, MD, MPH, FACC, FSCAI Director, Interventional Cardiologist Athens Medical Center

Edwards-Sapien XT Valve

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Page 18: 1 Trancatheter Aortic Valve Implantation (TAVI) Georgios I. Papaioannou, MD, MPH, FACC, FSCAI Director, Interventional Cardiologist Athens Medical Center

CoreValve

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Page 19: 1 Trancatheter Aortic Valve Implantation (TAVI) Georgios I. Papaioannou, MD, MPH, FACC, FSCAI Director, Interventional Cardiologist Athens Medical Center

Valves Under Evaluation

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Page 20: 1 Trancatheter Aortic Valve Implantation (TAVI) Georgios I. Papaioannou, MD, MPH, FACC, FSCAI Director, Interventional Cardiologist Athens Medical Center

Valve Delivery Systems

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Page 21: 1 Trancatheter Aortic Valve Implantation (TAVI) Georgios I. Papaioannou, MD, MPH, FACC, FSCAI Director, Interventional Cardiologist Athens Medical Center

Preclose technique

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Page 22: 1 Trancatheter Aortic Valve Implantation (TAVI) Georgios I. Papaioannou, MD, MPH, FACC, FSCAI Director, Interventional Cardiologist Athens Medical Center

TAVI Route

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Page 23: 1 Trancatheter Aortic Valve Implantation (TAVI) Georgios I. Papaioannou, MD, MPH, FACC, FSCAI Director, Interventional Cardiologist Athens Medical Center

TAVI Screening

• Euroscore > 20%• STS Score > 10%• Echocardiogram• Coronary Angiography• CT Angiography (Aorta & Peripherals)

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Page 24: 1 Trancatheter Aortic Valve Implantation (TAVI) Georgios I. Papaioannou, MD, MPH, FACC, FSCAI Director, Interventional Cardiologist Athens Medical Center

CT Angiography (LVOT-Annulus-SOV-Aorta)

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Page 25: 1 Trancatheter Aortic Valve Implantation (TAVI) Georgios I. Papaioannou, MD, MPH, FACC, FSCAI Director, Interventional Cardiologist Athens Medical Center

CT Angiography (Peripherals)

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Page 26: 1 Trancatheter Aortic Valve Implantation (TAVI) Georgios I. Papaioannou, MD, MPH, FACC, FSCAI Director, Interventional Cardiologist Athens Medical Center

Screening Report

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Page 27: 1 Trancatheter Aortic Valve Implantation (TAVI) Georgios I. Papaioannou, MD, MPH, FACC, FSCAI Director, Interventional Cardiologist Athens Medical Center

Fluroscopic Image of Valve Release (CoreValve)

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Page 28: 1 Trancatheter Aortic Valve Implantation (TAVI) Georgios I. Papaioannou, MD, MPH, FACC, FSCAI Director, Interventional Cardiologist Athens Medical Center

Fluroscopic Image of Valve Release(Edwards-Sapien)

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Page 29: 1 Trancatheter Aortic Valve Implantation (TAVI) Georgios I. Papaioannou, MD, MPH, FACC, FSCAI Director, Interventional Cardiologist Athens Medical Center

Femoral Arterial Puncture (1)

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Page 30: 1 Trancatheter Aortic Valve Implantation (TAVI) Georgios I. Papaioannou, MD, MPH, FACC, FSCAI Director, Interventional Cardiologist Athens Medical Center

Femoral Arterial Puncture (2)

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Page 31: 1 Trancatheter Aortic Valve Implantation (TAVI) Georgios I. Papaioannou, MD, MPH, FACC, FSCAI Director, Interventional Cardiologist Athens Medical Center

Sheath Insertion (14-22 F)

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Page 32: 1 Trancatheter Aortic Valve Implantation (TAVI) Georgios I. Papaioannou, MD, MPH, FACC, FSCAI Director, Interventional Cardiologist Athens Medical Center

Baseline Aortography

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Page 33: 1 Trancatheter Aortic Valve Implantation (TAVI) Georgios I. Papaioannou, MD, MPH, FACC, FSCAI Director, Interventional Cardiologist Athens Medical Center

Aortic Valvuloplasty

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Page 34: 1 Trancatheter Aortic Valve Implantation (TAVI) Georgios I. Papaioannou, MD, MPH, FACC, FSCAI Director, Interventional Cardiologist Athens Medical Center

Valve Delivery System

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Page 35: 1 Trancatheter Aortic Valve Implantation (TAVI) Georgios I. Papaioannou, MD, MPH, FACC, FSCAI Director, Interventional Cardiologist Athens Medical Center

Initial Valve Release (CoreValve)

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Page 36: 1 Trancatheter Aortic Valve Implantation (TAVI) Georgios I. Papaioannou, MD, MPH, FACC, FSCAI Director, Interventional Cardiologist Athens Medical Center

Final Valve Release (CoreValve)

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Page 37: 1 Trancatheter Aortic Valve Implantation (TAVI) Georgios I. Papaioannou, MD, MPH, FACC, FSCAI Director, Interventional Cardiologist Athens Medical Center

Femoral Angiography after closure

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Page 38: 1 Trancatheter Aortic Valve Implantation (TAVI) Georgios I. Papaioannou, MD, MPH, FACC, FSCAI Director, Interventional Cardiologist Athens Medical Center

TAVI Vascular Arterial Complications

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Page 39: 1 Trancatheter Aortic Valve Implantation (TAVI) Georgios I. Papaioannou, MD, MPH, FACC, FSCAI Director, Interventional Cardiologist Athens Medical Center

TAVI Transapical Complications

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Page 40: 1 Trancatheter Aortic Valve Implantation (TAVI) Georgios I. Papaioannou, MD, MPH, FACC, FSCAI Director, Interventional Cardiologist Athens Medical Center

TAVI Mitral Valve Injury

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Page 41: 1 Trancatheter Aortic Valve Implantation (TAVI) Georgios I. Papaioannou, MD, MPH, FACC, FSCAI Director, Interventional Cardiologist Athens Medical Center

TAVI Paravalvular Regurgitation

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Page 42: 1 Trancatheter Aortic Valve Implantation (TAVI) Georgios I. Papaioannou, MD, MPH, FACC, FSCAI Director, Interventional Cardiologist Athens Medical Center

TAVI Annulus Rupture

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Page 43: 1 Trancatheter Aortic Valve Implantation (TAVI) Georgios I. Papaioannou, MD, MPH, FACC, FSCAI Director, Interventional Cardiologist Athens Medical Center

TAVI Coronary Obstruction

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Page 44: 1 Trancatheter Aortic Valve Implantation (TAVI) Georgios I. Papaioannou, MD, MPH, FACC, FSCAI Director, Interventional Cardiologist Athens Medical Center

Θερμές Ευχαριστίες (2015)

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Κατερίνα-Βασίλης Αριέττα

Φίλιππος