1 p romoting the creation, relocation and development of biotech companies
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PROMOTING THE PROMOTING THE CREATION, RELOCATION CREATION, RELOCATION AND DEVELOPMENT OF AND DEVELOPMENT OF BIOTECH COMPANIESBIOTECH COMPANIES
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Genopole®: From a Bio-Park to a Bio-Cluster ...Genopole®: From a Bio-Park to a Bio-Cluster ...
Companies
Hospital University
Research
A continuum dedicated to BiotechnologyA continuum dedicated to Biotechnology
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Genopole® : a Biopark fully integrated in the Genopole® : a Biopark fully integrated in the Medicen Paris Region Bio-clusterMedicen Paris Region Bio-cluster
Non-Profitable Non-Profitable
OrganisationOrganisation Incorporated in 1998Incorporated in 1998 Creation & Development of a Bio-Park : Companies & Creation & Development of a Bio-Park : Companies &
Research LabsResearch Labs
30 Km30 Km
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Genopole®: Genopole®: Building the most favorable Building the most favorable environment to develop Biotech companies… environment to develop Biotech companies…
International International
NetworkNetwork
Shared Shared
Technical platformsTechnical platforms
Incubation and Incubation and
development development
ProgramsPrograms
VersatileVersatile
Real Estate Real Estate
Offers and ServicesOffers and Services
Clinical Clinical
NetworkNetwork
International International
Scientific Scientific
environmentenvironment
Biotech Biotech CompaniesCompanies
Pre seed FundPre seed Fund
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20 research labs, incl. 3 national-scale 20 research labs, incl. 3 national-scale
centrescentres More than 900 scientistsMore than 900 scientists From major National Research AgenciesFrom major National Research Agencies
o ……
Genopole®: A stimulating Collaborative Scientific Genopole®: A stimulating Collaborative Scientific & Education Environment& Education Environment
ResearchResearch
Evry University and 3 engineer schoolsEvry University and 3 engineer schools more than 12,000 students (34 % in more than 12,000 students (34 % in wet sciences wet sciences and and
engineering)engineering) and 400 professors and 400 professors
Ambitious Integrative ProgramsAmbitious Integrative Programs iStem : Institute for Stem Cells (2005) iStem : Institute for Stem Cells (2005) iSSB : Institute for Systems and Synthetic Biology iSSB : Institute for Systems and Synthetic Biology
(2009) (2009) Institute for Biomaterials (2010)Institute for Biomaterials (2010)
A new hospital is build on Genopole® A new hospital is build on Genopole®
campuscampus
Genopole®: Genopole®: a new hospital and a center for a new hospital and a center for clinical and translational researchclinical and translational research
Latest & Largest General Hospital build in Latest & Largest General Hospital build in
FranceFrance1,000 beds1,000 bedsOpening May 2011Opening May 2011Genopole Genopole coordinates the construction of coordinates the construction of
a a center for clinical and translational researchcenter for clinical and translational research
Clinical
Clinical
3,000 m²3,000 m²New ApproachesNew ApproachesOpening late 2011Opening late 2011
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Our facilities include space Our facilities include space from from “plug ‘n play” offices for “plug ‘n play” offices for
entrepreneurs to customised tenant lab & office spacesentrepreneurs to customised tenant lab & office spaces
for 50 to 300 m² wet lab & office suitesfor 50 to 300 m² wet lab & office suites Fully equipped with benches, sinks, deionised water, Fully equipped with benches, sinks, deionised water,
autoclave, freezers, rt-PCR, …autoclave, freezers, rt-PCR, …
Genopole®: Genopole®: more than 83 000 m² dedicated to the more than 83 000 m² dedicated to the development of life science companiesdevelopment of life science companies
Incubator with shared laboratory Incubator with shared laboratory
equipmentequipment
Offices fully furnished, Offices fully furnished, Meeting rooms, ... Meeting rooms, ...
Real EstateReal Estate
Business Center (20-50 m²):Business Center (20-50 m²):
customized spaces / specific demand and lay customized spaces / specific demand and lay
outout for 300 to 2 000 m² and more wet lab, L2 & office for 300 to 2 000 m² and more wet lab, L2 & office
suitessuites
Genopole®: Genopole®: State of the art shared technical State of the art shared technical platforms and equipmentplatforms and equipment
Infrastructures
Infrastructures
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15 Platforms/Equipments end 200915 Platforms/Equipments end 2009
Management : 13 public labs, 1Management : 13 public labs, 1 private and 1 Genopoleprivate and 1 Genopole
Genopole investments Genopole investments ~ 20 M€~ 20 M€
Headcount : 68 personsHeadcount : 68 persons
Cumulated surface ~ 4200 mCumulated surface ~ 4200 m22
5 obtained national quality label5 obtained national quality label
2 ISO 9001 v 2000 certification & 2 2 ISO 9001 v 2000 certification & 2 planned in 2009-2010planned in 2009-2010
more than 300 scientific publicationsmore than 300 scientific publications
8 patents/licences8 patents/licences
Sharing expertise, skills and resourcesSharing expertise, skills and resources
Genopole®: Genopole®: State of the art shared technical State of the art shared technical platforms and equipmentplatforms and equipment
Infrastructures
Infrastructures
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CERFE and CERFAP(Animal facilities)CERFE and CERFAP(Animal facilities) Cell and Small Animal IrradiatorCell and Small Animal Irradiator Imaging and cytometry platformImaging and cytometry platform Bioinformatic annotationBioinformatic annotation DNA chips productionDNA chips production Mass spectrometryMass spectrometry platformplatform Evr@PlatformEvr@Platform (augmented reality and virtual environment)(augmented reality and virtual environment) Plant DNA Microarray platform Plant DNA Microarray platform Biophotonics PlatformBiophotonics Platform Structural Biology Platform (NMR, AFM)Structural Biology Platform (NMR, AFM) Transmission electron microscopyTransmission electron microscopy DNA and cells BankDNA and cells Bank HTS PlatformHTS Platform Cell sorting stationCell sorting station Incubator shared equipementsIncubator shared equipements
15 Platforms15 Platforms
Genopole®: Genopole®: GMP production centers for drugs of GMP production centers for drugs of the futurethe future
Infrastructures
Infrastructures
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The Present & the FutureThe Present & the Future
A A GMP GMP compliantcompliant biomanufacturingbiomanufacturing center for center for proteinsproteins from mammalian cells (biotherapy, from mammalian cells (biotherapy, monoclonal antibodies)monoclonal antibodies)
A A GMPGMP compliant compliant viral vector viral vector bioproduction bioproduction center (Genethon)center (Genethon)
A production centre of A production centre of enzymesenzymes and and biocatalysisbiocatalysis for industrial use. for industrial use.
A A GMP biomanufacturing GMP biomanufacturing centre using centre using alternative techniques : alternative techniques : bacteriabacteria, , yeastyeast, , plantsplants……
An An GMPGMP oligonucleotidesoligonucleotides production center in production center in partnershippartnership
A Laboratory to develop and optimise the best A Laboratory to develop and optimise the best expression systemsexpression systems
A centre for A centre for filling, packaging and delivering filling, packaging and delivering products under products under GMPGMP compliant compliant
Genopole®: Genopole®: a team dedicated to foster creation a team dedicated to foster creation and development of biotech companiesand development of biotech companies
IncubationIncubationFinance
Science(s)
IP
Team
Clinic&Reg Scale up
6420
Finance
Science(s)Market Compet Bus Dev
IP
Team
Clinic&Reg Scale up
6420
Market Compet. Bus Dev
A Team of 6 multidisciplinary A Team of 6 multidisciplinary
Project ManagersProject Managers
Combining solid complementary Combining solid complementary
backgrounds in pre-incubation, backgrounds in pre-incubation,
IP, finance, valuations, biz. dev., IP, finance, valuations, biz. dev.,
fund raising, licensing, …fund raising, licensing, …
Genopole®: Genopole®: a team dedicated to foster creation a team dedicated to foster creation and development of biotech companies…and development of biotech companies…
IncubationIncubation
Legal support for Legal support for
corporate developmentcorporate development
Incorporation PhaseIncorporation Phase Development PhaseDevelopment Phase
Raise Private MoneyRaise Private Money Network of BAs and VCsNetwork of BAs and VCs
Business DevelopmentBusiness Development Direct Access to all French Tech Transfer Offices Direct Access to all French Tech Transfer Offices
(CNRS, Inserm, CEA, AP-HP, …)(CNRS, Inserm, CEA, AP-HP, …) Network of business opportunitiesNetwork of business opportunities Network of international expertsNetwork of international experts
Raise Public MoneyRaise Public Money Direct relations with Direct relations with
OSEO, CFI, ANR, Medicen, OSEO, CFI, ANR, Medicen,
……
Access to the Best R&D tax Credit in Access to the Best R&D tax Credit in
EuropeEurope Cover 50% of all R&D costs in the 1Cover 50% of all R&D costs in the 1stst year year 40% the 240% the 2ndnd year and 30% in subsequent year and 30% in subsequent
years up to €100 million and 5% aboveyears up to €100 million and 5% above
Drug DevelopmentDrug Development Network of preclinical & clinical Network of preclinical & clinical
expertsexperts Access to French and European Access to French and European
authorities: authorities: AFSSAPS or EMEAAFSSAPS or EMEA
Genopole provides a whole list of services Genopole provides a whole list of services
dedicated to young biotech companiesdedicated to young biotech companies
Genopole®: Genopole®: a list of services to foster the a list of services to foster the development of Biotech companiesdevelopment of Biotech companies
Senior administrative officers, Accounting, quality Senior administrative officers, Accounting, quality
assurance, onsite IT network support, human resources assurance, onsite IT network support, human resources
management, … management, … Genopole Genopole coordinates coordinates an European Grant an European Grant
Service dedicated to SMEs ...Service dedicated to SMEs ... Brings support to preparation and application phases but Brings support to preparation and application phases but
also in the management of funded projectalso in the management of funded projectBureau
Euro
pe
Genop
ole
®
IncubationIncubation
Genopole organises access to :Genopole organises access to : Electronic libraries including scientific and competitive Electronic libraries including scientific and competitive
databasesdatabases Annual Calls for Equipments and Post-DocsAnnual Calls for Equipments and Post-Docs
G1J - Genopole pre-seed Life Sciences Capital FundG1J - Genopole pre-seed Life Sciences Capital Fund
Genopole®: with G1J IdF Genopole®: with G1J IdF access to a pre-seed access to a pre-seed FundFund
Initial Capital: 2.1 M€ - 16 private investorsInitial Capital: 2.1 M€ - 16 private investors
Investment/project: 50 000 – 100 000 €Investment/project: 50 000 – 100 000 €
« From 1st day to 1st round of financing »« From 1st day to 1st round of financing »
Allows access to the Oseo grant system and to National, Regional & EU grantsAllows access to the Oseo grant system and to National, Regional & EU grants
Equity raise: 6 M€ Equity raise: 6 M€ brings G1J to the Proof of Concept Fund level brings G1J to the Proof of Concept Fund level Investment/project:Investment/project: 300 000 – 500 000 € 300 000 – 500 000 €
IncubationIncubation
G1J - Genopole Regional Life Sciences Capital FundG1J - Genopole Regional Life Sciences Capital Fund
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Genopole®: Genopole®: More than 80 currently incorporated More than 80 currently incorporated companies and active projects …companies and active projects …
LTK LTK PharmaPharma
NanoBNanoBHH
GlobalBio GlobalBio EnergyEnergy
Texcell Texcell
GENOPOLEGENOPOLE®® ENTREPRISES ENTREPRISES in 2008in 2008
69 biotech companies69 biotech companies
1023 FTE1023 FTE
207.81 M€ fund raised 207.81 M€ fund raised
144.11 M€ sales / 30 companies144.11 M€ sales / 30 companies
670 granted/penting patents670 granted/penting patents
28 products from IND to Phase III & 28 products from IND to Phase III & marketmarket
Genopole manages an international networkGenopole manages an international network
Genopole®: an international network oriented to biotech companies
with international Cies, pharma with international Cies, pharma
laboratories, foreign bioincubators and laboratories, foreign bioincubators and
international venture capital institutions,international venture capital institutions,Genopole is member of several European Genopole is member of several European
consortium with European bioparks consortium with European bioparks
InternationalInternational
BioLink (FP5) BioLink (FP5) Oxford, Munich, Cagliari, Jerusalem, Oxford, Munich, Cagliari, Jerusalem,
CardiffCardiff
Natibs (FP6) Natibs (FP6) Berlin, Barcelona, Karolinska, Tallinn, Tel Aviv, Berlin, Barcelona, Karolinska, Tallinn, Tel Aviv,
InnoInno
CEBR (FP6) CEBR (FP6) Cambridge, Oxford, Berlin, Munich, Heidelberg, Barcelona, Uppsala, Cambridge, Oxford, Berlin, Munich, Heidelberg, Barcelona, Uppsala,
Tallinn, LyonTallinn, Lyon
Bio-CT (FP7) Bio-CT (FP7) Torino, Cambridge (CEBR), Barcelona, Berlin, Debrecen & InnoTorino, Cambridge (CEBR), Barcelona, Berlin, Debrecen & Inno
Genopole® Campus 1 Today & tomorrow Genopole® Campus 1 Today & tomorrow
Pépinière
CCIE
Genopole
Entreprises
Centre de Bioproduction
Projet Gamma : production GM P de lots cliniques de vecteurs viraux de Généthon 2011
Centre Hospitalier Sud-Francilien
2011
Projet Crèche2011
Restaurant inter-entreprises et Résidence hôtelière 2011
Genavenir : Pôle d’entreprises et de laboratoires
Genavenir :Hôtels
d’entreprises
Centre de Recherche Clinique et Translationnelle
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2020 research labsresearch labs - 900 jobs - - 900 jobs - 70 biotech companies 70 biotech companies – 1 000 jobs-– 1 000 jobs- A comprehensive A comprehensive 83 000 m² 83 000 m² real estate real estate
offeroffer A team A team dedicated to developmentdedicated to development Services and a Europe Grant serviceServices and a Europe Grant service 1717 platforms and equipmentsplatforms and equipments Corbeil Evry Corbeil Evry HospitalHospital & Clinical & Clinical
and and Translational Research CenterTranslational Research Center GMP GMP Biomanufacturing Biomanufacturing Center opening Center opening
soon and 4 others biomanufacturing soon and 4 others biomanufacturing project runningproject running
Our achievements ...Our achievements ...
For more Informations …For more Informations …
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http://www.genopole.fr
Emmanuel DIAZEconomic Development DirectorPlace de l’Agora BP 6291002 EVRY Cedex Tel + 33 (0)1 69 91 59 38
Caroline MercierHead of networks and investmentsEssonne Development Agency6 cours Monseigneur Roméro91025 Evry Cedex Fixe : + 33 (0)1 69 91 42 56mail : [email protected]
Delphine BeauLife Sciences Director Paris Region Economic Development Agency www.paris-region.comTel :(+33 (0)1 58 18 69 62 Mob.:+33 (0)6 03 85 66 32
Eric LameignèreGenopole Entreprises
Director5, rue Henri DesbruèresF-91057 Evry Cedex
Tel.: +33 (0)160 878 306 Tel :(+33 (0)1 58 18 69 62 Mob.:+33 (0)6 03 85 66 [email protected]