1 nanoram keegan a. mchose regional sales manager handheld raman spectrometer |

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NanoRam

Keegan A. McHoseRegional Sales Manager

Handheld Raman Spectrometer

www.bwtek.com | www.nanoram.com

http://www.bwtek.com/

http://www.nanoram.com/

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We are Your Spectroscopy PartnerGlobal leader with > 10,000 Portable and handheld Raman systems

B&W Tek, China Ming Shen Commercial Plaza 400 CaoBao Rd., Suite 2206, Shanghai - 200233, China Phone: +86 021-64515208

B&W Tek, Japan 2-3-2 7F, Kamiochiai, Chuo-ku, Saitama-city, Saitama - 338-0001, Japan Phone: +81(0)48 851 3150

B&W Tek, Corporate Headquarters 19 Shea Way Newark, DE 19713, USA Phone: +1-302-368-7824 Web: www.bwtek.com

B&W Tek, Europe Seelandstraße 14-16, 23569 Lübeck, Germany Phone: +49(0)45130803854




Raman Spectroscopy

3www.bwtek.com | www.nanoram.com

1 photon : 1,000,000

Raleigh

Unchanged Elastic

Scattering

RamanInelastic Scattering

Laser785 nm Excitation




Mid-IR NIR reflectance Raman

Mechanism: absorption by fundamental molecular vibrational modes

Molecular Specificity: high

Signal Strength: strong

Energy: 600-4000 cm-1

Sampling: direct material contact required, glass and water appear opaque; can rarely see through container materials

Hardware: probes extremely expensive, and short in length, size and weight

Mechanism: absorption by harmonics of fundamental vibrational modes of X-H bonds (e.g., N-H, O-H)

Molecular Specificity: low

Signal Strength: weak

Energy: 4000-12,500 cm-1

Sampling: non-contact, but close proximity to material required (<5 mm)

Hardware: longer probes possible (meters); quartz optics; dispersive, interferometry common

Mechanism: inelastic scattering by vibrational, rotational, low frequency molecular modes.

Molecular Specificity: high

Signal Strength: weak

Energy: 176-3200 cm-1

Sampling: container interference is mitigated by accessories

Hardware: CCD detection; quartz optics; long probes common (kilometers in some cases)



Technical Specifications


NanoRamBWS455

Detector TE Cooled linear CCD Array

Excitation 785nm ± 0.5nm, Stability <0.5cm-1, Linewidth <2.0cm-1

mW tunable from 0 mW to 300 mWLaser Power Control 0 to 100% in 10% increments

Range / Resolution

176cm-1 to 2900cm-1~ 9.0 cm-1 @ 785nm

Display High Visibility OLED touch screen, 3.7" size

Barcode Reader 1D and 2D barcodes

Data Formats .txt, .csv, .spc

DC Power 12V DC at 6.6 Amps

Battery Rechargeable Li-ion Battery, > 5 hours operation

PC Software NanoRam IDComputer Interface USB 2.0, Wifi



NanoRam

Raman Technology Optimal excitation

wavelength of 785nm to reduce fluorescence

Complies with USP<1120> and EP Ch.2.2.48 guidelines for Raman spectroscopy

Accepted cGMP analytical testing method to replace wet chemistry: ICH Q2 R1




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NanoRam

Innovations State of the art laser and

cooled sensor technology increases sensitivity

Open software design for third party software applications

Transfer libraries from instrument to instrument easily




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NanoRam

Lean Material Lifecycle

Incoming non-destructive testing of Raw Materials

Reducing Waste in the Dispensing Suite

Plastic Packaging Identification

At line identification of intermediates

Final product identification Substandard, Adulterants, and Counterfeit Deterrent




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No sample preparation required Scan through:

Polyethylene Bags Borosilicate Glass

Vials Disposable Pipette

Touch Screen allows for quick documentation of sample information

NanoRam

Ease of Use




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Performance Qualification using polystyrene takes less than one minute

Wireless reporting for reduced documentation lead time

Remote Administration to reduce unit down time

Clear Pass/ Fail results Attachments provide laser

safety with built in interlock

NanoRam

Ease of Use




NanoRam

Good Documentation Practices

Fully Traceable results with: Time/ Date Stamps User System Presets Etc.

Personalize to your company reporting preference with NID

Reported to a secure database that can be linked to your LIMs


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NanoRam

Technical Support IQOQPQ Services

Execution Validation Documentation SOP Templates

Admin Developer General User Training

On-site method development, training and other support services available

Customer support 24/7 Phone Line


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NanoRam

Regulatory Compliance Supports CFR21 Part 11 Electronic

Records and Signature Protocols Supports CFR21 Part 1040.10

Performance Standards for Light Emitting Products

Complies with USP<1120> and EP Ch.2.2.48 guidelines for Raman spectroscopy

ASTM E1840 Raman Shift Standards for spectrometer calibrations


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NanoRam

Warranty Programs

One year factory warranty comes standard

Extended warranty programs of 2 or 3 years can be additionally purchased

All warranties can be combined with calibration service


1 nanoram keegan a. mchose regional sales manager handheld raman spectrometer |

Documents

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