1. members of the research group and collaborators20191303103225/Årsrapport 2018... · forekomst...

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Annual report 2018 Women’s Health & Perinatology Research Group (Forskningsguppe Kvinnehelse og perinatologi),

Department of Clinical Medicine, Faculty of Health Sciences,

UiT-The Arctic University of Norway, Tromsø

1. Introduction Women’s Health and Perinatology Research Group has been working actively in research and education since

its establishment in 2009 with the aim of enhancing health and wellbeing of women and babies. We focus on

clinical, basic and translational researches as well as epidemiological studies related to obstetrics, maternal-

fetal medicine, perinatal medicine, female incontinence and reproductive medicine.

2. Members of the research group and collaborators Permanent staffs

Purusotam Basnet, Professor (20%), Research Group Leader (Current)

Ganesh Acharya, Professor (20%), Research Group Leader (2009-2016)

Pål Øian, Professor (20%), Research Group leader (2016-2018) (retire in 2018)

Åse Vårtun, Technical Staff, Senioringeniør (100%)

Other staffs

Francesco D’Antonio, Associate Professor (100%)

Åshild Bjørnerem Associate Professor (70%) and consultant at UNN (30%)

Ingard Nilsen, Assistant Professor (20%)

Anne Beate Vereide, Associate Professor (20%). Anne Beate Vereide is employed at the Department

of Clinical Medicine, Obstetrics and Gynecology, but is associated with Gynecological Oncology

Research group at the Department of Medical Biology

Øystein Pedersen, Clinical Lecturer (50%) from 31. 08. 2018 and (20%) until 31.08.2018

Anne Hansson, Clinical Lecturer (10%)

Amarnath Bhide, Associate Professor (10%)

PhD candidates

1. Christian Widnes (no funding in 2018, employed at UNN)

2. Elisabeth Ludvigsen (50% external funding, Helse-Nord)

3. Madhu Wagle (no funding in 2018)

4. Qiongjie Zhou (50% external funding, Fudan University, Shanghai, China)

5. Tonje Lippert (no funding in 2018)

6. Siv Boon Mundal (100% supported by NTNU, Trondheim)

7. Priya Bhide (50% external funding by Hommerton Hospital, London, UK)

8. Ane Sigrid Nygaard (100% external funding, Fysiofondet/HelseNord, maternity leave until April 2018)

9. Dariya Popova (100% external funding, UiT strategic grant 2016)

10. Marit Osima (100% internal funding – EpiNor Research School)

11. Rita Kral (100% external funding from Helse Nord Dec 2016)

12. Camilla Andreasen (100% external funding HELSEFORSK)

13. Tove Tveitan Borgen (100% external funding HELSEFORSK)

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14. Hanne Frøyshov (no funding in 2018, employed at Helse-Nord)

Postdoc. candidate

1. May Wenche Jøraholmen (100% external funding, Helse Nord)

Local collaboration

Natasa Skalko-Basnet: Drug Transport and Delivery Research Group, IFA, UiT

Anne Husebekk, Bjørn Skogen and Heidi Tiller: Immunology Research Group, IMB, UiT

Kirsti Ytrehus: Cardiovascular Research Group, IMB, UiT

Tore Sørlie: Psychiatry Research Group, IKM, UiT

Henrik Schirmer: Department of Heart Medicine, UNN

Trond Flægstad, Per Ivar Kaaresen and Claus Klingenberg: Pediatric Research Group, UiT

Tom Wilsgaard: ISM, UiT

Gunnar Leivseth: IKM, UiT

Ellisiv Mathiesen and Stein Harald Johnsen: Brain and Circulation Research Group, UiT

Balpreet Ahluwalia: Department of Physics, UiT

Lotta Halvorsen: UNN

Hilde Nerum: UNN

Ragnar Martin Joakimsen: Department of Medicine, UNN

Elin Richardsen: Department of Pathology, UNN

Ann Kristin Hansen, Gunnar Knutsen, and Jan Elvenes: Department of Orthopaedic Surgery, UNN

Marit Waaseth: Department of Pharmacy, UiT

Anne Elise Eggen: Department of Community Medicine, UiT

Lars Marius Ytrebø: OPIN klinikken, UNN og UiT

National collaboration

Vasilis Sitras: OUS, Oslo

Kari Flo: AHUS, Oslo

Rolf Gunnar Jørstad: Norsk pasientskadeerstatning (The Norwegian System of Compensation to

Patients)

Lars T Johansen: Statens helsetilsyn (The Norwegian Board of Health Supervision)

Signe Egenberg: Stavanger Universitetssykehus

Ann-Charlotte Iversen: Institutt for kreftforskning og molekylær medisin, Det medisinske fakultet,

Norges teknisk naturvitenskapelige universitet (NTNU) Trondheim

Mona Stedenfeldt: St. Olavs Hospital and Nasjonalt Kompetansesenter for inkontinens og

bekkenbunnsykdom (Norwegian National Advisory Unit on Incontinence and Pelvic Floor Health)

Ellen Blix: Oslo Met

Stine Bernitz: Oslo Met

Torbjørn Eggebø: NTNU og Nasjonalt senter for fostermedisin, St. Olavs Hospital.

Tone Kristin: Omsland UiO

Erik Fink Eriksen, Frede Frihagen, Lars Nordsletten og Lene B Solberg: UiO and OUS

Torbjørn Wisløff: UiO and FHI

Wender Figved: Bærum Hospital

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Tove Tveitan Borgen: Drammen Hospital

Jan-Erik Gjertsen og Ellen Apalset: UiB og Haukeland Hospital

Trude Basso: NTNU og St. Olavs Hospital

Gunnhild Hagen: FHI

International collaboration

Juha Räsänen: Oregon Health and Science University, Portland, USA and University of Helsinki, Finland

Tiina Erkinaro: Oulu University Hospital, Oulu, Finland

Roy Homburg: London, UK

Anthony Odibo: Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology,

Morsani College of Medicine, University of South Florida, Tampa, FL, USA.

Agata Wloch: Medical University of Silesia, Katowice, Poland

Magnus Westgren and Sven-Erik Sonesson: Karolinska Institutet, Stockholm, Sweden

Jim Zhang: Xinhua Hospital, Shanghai Jiatong University School of Medicine, Shanghai, China

Xiaotian Li: Fudan University, Shanghai, China

Jouko Pirhonen, Finland

Mike Robson: National Maternity Hospital, Dublin, Ireland

Minh Bui, John L Hopper, and Susan P Walker, University of Melbourne, Australia

Stephen Hodges: Royal Veterinary College, London, UK

Basky Thilaganathan: Fetal Medicine Unit, Division of Developmental Sciences, St. George’s University

of London, London

Aris Khalil: Fetal Medicine Unit, Division of Developmental Sciences, St. George’s University of London,

London

Asma Papagheorghiou: Fetal Medicine Unit, Division of Developmental Sciences, St. George’s University

of London, London

C. Garel: Hôpital d'Enfants Armand-Trousseau - Service de Radiologie, Paris, France, 75571

ML. Moutard: Service de Neuropédiatrie, Hôpital Trousseau, Hôpitaux Universitaires de l'Est Parisien,

Université Pierre et Marie Curie, Paris, France

G. Pilu: Department of Obstetrics and Gynecology, Sant'Orsola-Malpighi Hospital, University of Bologna,

Bologna, Italy

G. Rizzo: Department of Obstetrics and Gynecology, Università di Roma, Tor Vergata, Roma, Italy

T. Lerman-Sagie: Fetal Neurology Clinic and Paediatric Neurology Unit, Wolfson Medical Center, Holon,

Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel

G. Malinger: Fetal Neurology Clinic and Paediatric Neurology Unit, Wolfson Medical Center, Holon,

Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel

L. Manzoli: Department of Medicine and Aging Sciences, University of Chieti-Pescara, Italy; EMISAC, CeSI

Biotech, Chieti, Italy

P. Lim: Department of Radiology, Abington Hospital, Abington, PA, USA

K. Hack: Department of Gynaecology and Obstetrics, Diakonessenhuis, Utrecht, Netherlands

Dilip Mehata: Indian Institute of Technology, New Dehli, India

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3. Research

Research focus

Fetal physiology and perinatal medicine

Basic and translational research in perinatology using animal models

Pregnancy and maternal mental health

Reproductive and perinatal epidemiology

Preeclampsia and its long-term consequences

Placental biology including genomics and proteomics

Reproductive endocrionology, preimplantation biology and clinical assisted reproduction technology

Female incontinence and pelvic physiology

Gestational diabetes

Bone fragility

Secondary fracture prevention

International projects

Project leader Collaborator Research title Funded by

Juha Räsänen

University of Oulu,

Oulu, Finland

Ganesh

Acharya

Experimental studies on fetal

cardio-vascular function in a

sheep model

University Hospital of Oulu,

Finland and Helse-Nord

Norway

Balpreet Ahluwalia,

Department of

Physics, UiT

Purusotam

Basnet

Subcellular anatomy of live cells

using Nanoscopy in collabotation

with the team of prof Dilip

Mehata, IIT, New Dehli, India

NFR, Norway

Post-doctoral research project

Postdoc researchers Collaborator Research title

Stine Bernitz Pål Øian Labour progression study (LaPS)

May Wenche

Jøraholmen

Purusotam Basnet,

Ganesh Acharya

Targeted therapy of genital chlamydia infections:

acting locally, efficiently and patient-friendly

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PhD degree award

PhD degree projects (Currently ongoing)

PhD researcher Main supervisor and co-

supervisors

Thesis title Funding

Mona Nystad

(Defended on

01.03.2018 at

UiT)

Ganesh Acharya (principal

supervisor); Vasilis Sitras

(co-supervisor, Oslo

University Hospital)

Role of Laeverin in the pathophysiology

of preeclampsia.

Helse Nord

Marit Osima

(Defended on

28.03.2018 at

UiT)

Åshild Bjørnerem (principal

supervisor), Erik Fink Eriksen

(co-supervisor, UiO)

Cortical porosity, medullary adiposity,

type 2 diabetes mellitus, serum vitamin

D, parathyroid hormone, and

nonvertebral fracture.

UiT Intern

Finansiering

EpiNor

Rita Kral

(Defended on

20.03.2018 at

UiT)


supervisor), Elin Richardsen

(co-supervisor, UiT)

Cortical bone and fracture risk: The

Tromsø Study

UNN

Helse Nord

Lotta Herling

(Defended in

06.04.2018 at

Karolinska

Institutet)


supervisor), Magnus

Westgren Peter Lindgren,

and Sven-Erik Sonesson (co-

supervisors, KI)

Functional studies of human fetal heart

with tissue Doppler imaging

Karolinska

Institutet

and

HeleseNord

PhD researcher Main supervisors and co-

supervisors

Project title Funding

Christian

Widnes


supervisor); Kari Flo and

Anne Husebekk (co-

supervisor), IMB

Maternal endothelial function and

feto-maternal hemodynamics in

normal and complicated pregnancies:

An observational study

UNN

Madhu Wagle Ganesh Acharya (principal

supervisor); Purusotam

Basnet (co-supervisor)

Self reported oral health awareness

and attitude towards dental care and

risk of dental caries among pregnant

woman in Norway

None

Qiongjie Zhou Ganesh Acharya (Principal

supervisor); Xiaotian Li ( co-

supervisor)

Epidemilogical map of TORCH

infections in the preconception period

among women of reproductive age in

rural China: A population-based nation

wide study

Fudan

University

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Camilla

Andreasen


supervisor), Tone K

Omsland, Cecilie Dahl,

Torbjørn Wisløff (co-

supervisors, UiO)

NoFRACT-

Norwegian Capture the Fracture

Initiative

HELSE-

FORSK NFR-

utlysning

Tove Tveitan

Borgen

Åshild Bjørnerem (Project

leader and co-supervisor),

Erik Fink Eriksen (principal

supervisor, UiO)

NoFRACT-

Norwegian Capture the Fracture

Initiative

HELSE-

FORSK NFR-

utlysning

Hanne

Frøydhov

Åshild Bjørnerem (co-

supervisor) Torgeir Engstad

(principal supervisor), Dag S

Halvorsen (co-supervisor)

Hjerneslag, risikofaktorer og prognose.

Helse Nord og Helse Midt.

Helse Nord

Tonje Lippert Pål Øian (principal

supervisor)

Birth outcome according to risk status

at admission in birth and changes in risk

status during labour

Sykehuset

Asker og

Bærum

Ane S. Nygaard Pål Øian (principal

supervisor); Gro K Haugstad

and Mona Stedenfeldt (co-

supervisors)

Group based somatocognitive

physiotherapy for women with chronic

pelvic pain. A randomized controlled

trial.

Fysiofondet

Helse Nord

Elisabeth

Ludvigsen

Finn-Egil Skjeldestad

(principal supervisor)

Fødselsrelatert urininkontinens og

prolaps (FRURIPRO)

Helse-Nord

Siv Boon

Mundal

Ann-Charlotte Iversen

(principal supervisor),

NTNU, Ganesh Acharya (co-

supervisor)

Oxidative stress in placental decudia

among preeclamtic women

NTNU

Dariya Popova Purusotam Basnet (principal

supervisor) and Ganesh

Acharya (co-supervisor)

Subcellular anatomy of preimplantion

human embryo using Nanoscopy

Tecnology.

(a strategic grant approved by UiT and

started from 2016)

UiT

Rebecka Dalbye Ellen Blix (principal

supervisor) Pål Øian (co-

supervisor)

Labor progression study (LaPS). A

cluster randomized study in 14

obstetric departments

Sykehuset

Østfold

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Master level research projects

Elise Sletten

(50%)

Anne Ørbo (principal

supervisor); Anne Beate

Vereide (co-supervisor)

Significance of progestogen therapy in

endometrial proliferative conditions

UiT

Priya Bhide Ganesh Acharya (principal

supervisor); Roy Homburg

(co-supervisor)

Role of ovarian reserve markers in

fertility management

UiT

Master student Supervisors Research title

Nikita Baiju

(Completed 2018)

Rigmor Berg (main

supervisor)

Ganesh Acharya (co-

supervisor)

Self-assessment of the outcome of first

timester medical abortion compared

to Clinical followup: A systematic

review

Master of

Public Health,

ISM

Stefan Thomassen

(Completed 2018)

Purusotam Basnet (main

supervisor)

Effect of liposomal resveratrol on

sperm cell motility

MED-3950

Master,

5.-årsoppgave.

Martine U. Glasø (Completed 2018)

Åshild Bjørnerem (main supervisor), Camilla Andreasen (co-supervisor)

Forekomst av komplikasjoner hos gravide med og uten diabetes

MED-3950 Master, UiT 5.-årsoppgave.

Veronica G. Rognli

(Completed 2018)

Åshild Bjørnerem (main

supervisor), Camilla

Andreasen (co-supervisor)

Behandling og oppfølging av brudd-

pasienter med beinskjørhet ved UNN

MED-3950

Master,

5.-årsoppgave.

Arja E. Arnesen (Ongoing)

Åshild Bjørnerem (main supervisor), Camilla Andreasen (co-supervisor)

Forekomst av diabetes blant gravide og svangerskapsutfall

MED-3950 Master, UiT

Mari Hansen

(Ongoing)

Øystein Pedersen Behandling av ekstrauterint

svangerskap ved UNN, 2006-2016

MED-3950

Master, UiT

5.-årsoppgave.

Kristine Knutsen

(Ongoing)

Mona Nystad (main

supervisor) and Purusotam

Basnet (co-supervisor)

Nanoscopic study on preclamptic and

norpreclamptic placenta

Mater of IMB

Shaeen Khan

(Ongoing)

Purusotam Basnet (main

supervisor) and Åse Vartun

(co-supervisor)

Effect of alcohol on sperm cell motility

and viability

MED-3950

Master,

5.-årsoppgave.

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Ongoing project description

Ganesh Acharya

His research activity mainly focuses on the investigation of fetal and maternal cardiovascular changes in

physiological and pathological pregnancies. The focus is on the translational aspect utilizing experimental

animal models as well as clinical material and epidemiological data in our research. Some of the ongoing

projects are outlined below.

Experimental studies on maternal and fetal cardio-vascular function using animal models

This is an ongoing collaboration with Prof Juha Räsänen (University of Helsinki, Finland), Oregon Health

Sciences University, Portland, USA and University of Oulu, Finland for more than 16 years. Currently we

are conducting experiments on fetal sheep to study fetal cardiovascular function and myocardial

remodelling under different loading conditions using conventional echocardiography, myocardial tissue

Doppler imaging, ultrasonic flow probes and pressure volume conductance catheters in vivo. We are also

investigating the feasibility of applying new echocardiographic techniques such as colour tissue velocity

imaging in diagnosing fetal hypoxemia/acidemia. We are testing the possibility of using certain

pharmaceutical preparations to increase fetal left ventricular preload by improving fetal pulmonary blood

flow, which may be useful in preventing/ameliorating cerebral hypoxemia in intrauterine growth

restricted fetuses.

Genetic and molecular markers of feto-maternal diseases

We are attempting to identify, characterize and clinically validate novel markers of preeclampsia and

placental and decudial dysfunctions.

Noninvasive assessment of cardiac function and systemic blood flow in human fetuses: An observational

study

This project is conducted in collaboration with Karolinska Institutet, Karolinska University Hospital and

Royal Technical Institute, Stockholm. In this project we plan to establish longitudinal reference ranges for

the parameters of heart function measured using tissue velocity imaging (this part of the study is

performed in Tromsø), apply this technique to identify fetuses at risk of complication due to hypoxemia

(IUGR, postdate pregnancy) and volume-overload (anemia due to red cell alloimmunization, twin-twin

transfusion syndrome), and develop an automated and easy way of measuring relevant parameters of

cardia function.

Maternal-fetal hemodynamics, endothelial function and placental blood flow

This is an ongoing large study evaluating maternal hemodynamics and endothelial function together with

several biomarkers to identify women at risk of pregnancy complications. Placental and fetal blood flow is

also simultaneously investigated. We are also studing sex diffrences in fetal and placental blood flow using

data collected in this study and previous studies. We have a biobank of blood samples and placental

samples collected from approximately 700 participants.

Long-term health and wellbeing of women with a previous history of pre-eclampsia

In this project we utilize the data from a large longitudinal population based-survey of Tromsø municipality

which has been ongoing for >40 years. Our main focus has been cardiovascular health of women with

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previous history of preeclampsia. The project is conducted in collaboration between our research group

and the Institute of Community Medicine, University of Tromsø.

Longitudinal changes in oral microbial milieu in normal pregnancy and pregnancy outcomes

Oral health in pregnancy is a neglected area of research. In this study in collaboration with the Institute of

Odontology in Tromsø we are investigating the longitudinal changes in oral microbial milljo during

pregnancy and their relation with pregnancy outcomes.

New nano-drug delivery systems for the treatment of vaginal infections

In collaboration with the “Drug-Delivery” Research group at the Department of Pharmacy, we are

developing new liposome-based nanodrug formulations for local delivery of intimicrobials and

antiinfammatory agents to the genital tract. One PhD thesis has been completed recently and one

postdoctorial project has been just started. The postdoctorial candidate will spend one year at Karolinska

Institutet.

Impact of free preconception care in rural China

In collaboration with Fudan University, Shangahi, China, we are utilizing a very large national dataset

collected during the implimentaion of National Free Preconception Health Care Project in China in selected

rural counties and some municipalities covering all 31 provinces in the country to study preconception risk

factors, vaccination status prevalence of TORCH infections and impact of free preconception care on

pregnancy outcomes. One PhD student financed by Fudan University is registered at UiT.

Pål Øian

In addition to ongoing Ph.D projects:

Obsteric anal sphincter tears

A project with national data from Finland and Norway. The project group: Jouko Pirhonen, Mika Gissler,

Mona Stedenfeldt and Pål Øian.

Maternal death in Norway

This is a national project on maternal death from the last 20 years and up-dated every year, also in

collaboration with other Scandinavian countries. Project leader Siri Vangen, The National Hospital,

Rikshospitalet, Oslo. Collaborator Pål Øian and The Norwegian Audit Group on maternal Death.

Claims in Obsterics and Gynecology – Norwegian Board of Health Supervision (Statens helsetilsyn)

Project leader Pål Øian collaborating with Lars T. Johansen, Geir Sverre Braut and Mike Robson.

Labor progression study (LaPS study)

This is a cluster-randomized study in 14 Norwegian hospitals testing out two different partograms. In

Norway and most other countries the Friedman’s partogram for labor progression has been used.

Contemporary research by Zhang shows that the dilatation of the cervix can be substantially different,

especially in the early stage of labor and a new partigram is developed. The type of partogram used is

important for the diagnosis of labor dystocia.

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In this study more than 70000 women are included and the inclusion process stopped 31 January 2017.

The primary outcome is cesarean section. Secondary outcomes are indications for cesarean section, the

rate of oxytocin augmentation, total duration of augmentation, duration of labor (first and second stage),

rate of dystocia, operative vaginal deliveries, bleeding > 500ml, Apgar score ≤7 at 5 minutes, metabolic

acidosis, transfer to NICU and women’s experience with birth care. Data are now being analyzed. Project

group: Stine Bernitz, Ellen Blix, Rebecka Dahlbye, Jim Zhang, Torbjørn Eggebø and Pål Øian

Home birth in Norway, Sweden, Denmark and Iceland

Project leader Ellen Blix collaborating with Pål Øian, Helena Lindgren, Olof Asta Olafsdottir, Hanne K

Hegaard and Merete Kumle.

Normal birth in an epidemiological and clinical perspective

Project leader Ellen Blix. Collaboration with Pål Øian

Mental health and labor

These projects are follow-up studies based on the PhD projects of Hilde Nerum and Lotta Halvorsen.

Project group: Hilde Nerum, Lotta Halvorsen, Tore Sørlie, Bjørn Straume, Pål Øian og professor Ingegerd

Hildingsson, Mitt-Sverige Universitet.

Purusotam Basnet

Semen quality and oxidative stress

Semen quality has been found to be deteriorating trend at large. One of the causes has been pointed to

the oxidative stress. A PhD project is developed to study semen quality among the healthy population and

men needed infertlty treatment in the Northern Norway and their root cause of deterioration together

with oxidative stress. Project leader Purusotam Basnet is working with collaborators, Ganesh Acharya and

Natasa Skalko Basnet.

Spermatozoa motility and viability

Different supplements in the media to increase in vitro motility and viability of sperm cells have been

screened. Project leader Purusotam Basnet is working with collaborator Natasa Skalko Basnet.

Oxidative stress in human embryo preimplantation stage

A preliminary method for the measurement of oxidative stress by using the tools and technology of

Nanoscopy in the pre-implanted human embryo is under development.

Subcellular anatomy of preimplanted human embryo using nanoscopy

This is a part of the project funded by UiT Strategic Grant for the establishment of Centre for Advanced

Nanoscopy to Decode Sub-cellular Biological Systems. This work package is approved by UiT for the PhD

research with Principal supervisor Purusotam Basnet and co-supervisors Ganesh Acharya, and Balpreet

Ahluwalia.

Norway-India Project

This is an international project between Norwegian partners (Department of Physics University of Tromsø,

University of Tromsø, University Hospital of North Norway, Tromsø) together with Indian partners (Indian

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Institute of Technology, New Dehli, India and other institutions). The grant is supported by Norwegian

Research Council. Main objectives of the study are to develop nonlabeling methods to study subcellular

structures using nanoscopy technique.

Åshild Bjørnerem

Research focus

Bone fragility - pathophysiology, diagnosis and prevention

Diabetes and pregnancy

Current research projects

Lactation, Menopause and Bone Health

The research on Lactation, Menopause and Bone Fragility based on data collected during her post-doctoral

in Melbourne, Australia is ongoing, with focus on 3D architecture of bone - to increase our understanding

of the pathophysiology behind bone fragility.

Pathophysiology and Diagnosis – Bone structure study

An extention of the Melbourne work after returning to Tromsø is a unique opportunity to test hypothesis

on diagnostic tools for assessment of fracture risk by using a relatively new software developed in

Melbourne for analysis of CT images, based on fracture cases and controls in the population-based Tromsø

study. This research focuses on pathophysiology of bone fragility, and diagnostic tool to better identify

those who are in need of treatment.

Secondary prevention of Fracture

NoFRACT – Norwegian Capture the Fracture Initiative is a huge national study involving secondary fracture

prevention. All women and men with fractures at seven Norwegian hospitals are identified, offered

examination and treatment for osteoporosis. The effect of introducing this intervention on re-fractures

rates and mortatlity will be measured using national registers during 2008-2020.

Diabetes and Pregnancy

A quality assurance study include women with and without diabetes during gestation in Northern Norway,

for assessment of complications of diabetes, and factors associated with complications.

Francesco D’Antonio

Prenatal diagnosis of abnormally invasive placenta (AIP) by ultrasound and MRI.

I am one of the lead investigators of a multicenter prospective study involving 20 centers in Italy aiming

at ascertaining the degree of association of different ultrasound and magnetic resonance imaging signs in

detecting the presence of AIP from the first trimester onwards. The data collection started last September.

Estimated completion date has been set in December 2017

Placental insufficiency and intra-uterine growth restriction.

I am part of the Truffle-2 Study, a multicenter prospective study involving several centers in Europe aiming

at ascertaining the role of fetal Doppler in identifying fetuses affected by late onset intra-uterine growth

restriction at higher risk of perinatal compromise.

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Multiple pregnancies

I am the lead investigator of the STORK group, a research collaborative including 9 hospitals in the South-

west region of Thames. Several studies have already been published in the last two years as part of my

PhD thesis. The data analysis is continuing; the main topic of the future publications will be perinatal

outcome of twin pregnancies after one twin death, perinatal morbidity in twin pregnancies affected by

birthweight discordance and perinatal outcome in high order multiple gestations.

Pre- and post-natal fetal Doppler

I am the lead investigator of a large prospective study carried out in Italy on the correlation between pre

and post-natal Doppler in uncomplicated preganncies and in those affected by intra-uterine growth

restriction.

Other members of the research group are involved in these prosjects (not presented above):

Utvikling av ny målemetode og behandlingsmetode hos kvinner med urininkontinens

Project leader Gunnar Leivseth collaborating with Ingard Nilsen.

Platelets and placenta – the new hotspot in fetal-matenal crosstalk

Project leader Heidi Tiller. Collaboration with Mona Nystad and Ganesh Acharya.

Maternal hemodynamics, endothelial function and placental blood flow.

Co-worker: Kari Flo (see also same projects under G. Acharya).

Placenta tissue imaging in Super Resolution by Nanoscopy

Collabotation with Balpreet Singh Ahluwalia, Luis Villagas Hernandez, Cristina Ionica Øie, Mona Nystad

and Purusotom Basnet.

Publications

1. Andreasen C, Solberg LB, Basso T, Borgen TT, Dahl C, Wisløff T, Hagen G, Apalset EM, Gjertsen JE, Figved

W, Hübschle HM, Stutzer JM, Elvenes J, Joakimsen RM, Syversen U, Eriksen EF, Nordsletten L, Frihagen F,

Omsland TK, Bjørnerem Å. Effect of a Fracture Liaison Service on the Rate of Subsequent Fracture Among

Patients With a Fragility Fracture in the Norwegian Capture the Fracture Initiative (NoFRACT) - A Trial

Protocol. JAMA Network Open. 2018. In press.

2. Bhide, Amar; Shah, Prakesh S.; Acharya, Ganesh. A simplified guide to randomized controlled trials. Acta

Obstetricia et Gynecologica Scandinavica 2018; 97.(4) s. 380-387.

3. Bhide, Amarnath; Acharya, Ganesh. Sex differences in fetal heart rate and variability assessed by antenatal

computerized cardiotocography. Acta Obstetricia et Gynecologica Scandinavica 2018.

4. Bjørnerem, Åshild; Wang, Xiaofang; Bui, Minh; Ghasem-Zadeh, Ali; Hopper, John L; Zebaze, Roger;

Seeman, Ego. Menopause-Related Appendicular Bone Loss is Mainly Cortical and Results in Increased

Cortical Porosity. Journal of Bone and Mineral Research 2018; 33.(4) s. 598-605.

5. Buca, Danielo Italo Pio; Khalil, Asma; Rizzo, Giuseppe; Familiari, Alessandra; Di Giovanni, Silvia; Liberati,

Marco; Murgano, Daniela; Ricciardulli, Alessandra; Fanfani, Francesco; Scambia, Giovanni; D'Antonio,

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Francesco. Outcome of prenatally diagnosed fetal heterotaxy: systematic review and meta-analysis.

Ultrasound in Obstetrics and Gynecology 2018; 51.(3) s. 323-330.

6. Buca, Danilo Italo Pio; Liberati, Marco; Calì, Giuseppe; Forlani, Francesco; Caisutti, Claudia; Flacco, Maria

Elena; Manzoli, Lamberto; Familiari, Alessandra; Scambia, Giovanni; D'Antonio, Francesco. Influence of

prenatal diagnosis of abnormally invasive placenta on maternal outcome: systematic review and meta-

analysis. Ultrasound in Obstetrics and Gynecology 2018; 52.(3) s. 304-309.

7. Caissutti, Claudia; Familiari, Alessandra; Khalil, Asma; Flacco, Maria E.; Manzoli, Lamberto; Scambia,

Giovanni; Cagnacci, Angelo; D'Antonio, Francesco. Small fetal thymus and adverse obstetrical outcome: a

systematic review and a meta-analysis. Acta Obstetricia et Gynecologica Scandinavica 2018; 97.(2) s. 111-

121.

8. Calì, Giuseppe; Forlani, Francesco; Foti, Francesca; Minneci, Gabriella; Manzoli, Lamberto; Flacco, Maria

Elena; Buca, Danielo Italo Pio; Liberati, Marco; Scambia, Giovanni; D'Antonio, Francesco. Diagnostic

accuracy of first-trimester ultrasound in detecting abnormally invasive placenta in high-risk women with

placenta previa. Ultrasound in Obstetrics and Gynecology 2018; 52.(2) s. 258-264.

9. Calì, Giuseppe; Forlani, Francesco; Minneci, Gabriella; Foti, Francesca; Di Liberto, S; Familiari, Alessandra;

Scambia, G.; D'Antonio, Francesco. First-trimester prediction of surgical outcome in abnormally invasive

placenta using the cross-over sign. Ultrasound in Obstetrics and Gynecology 2018; 51.(2) s. 184-188.

10. Calì, Giuseppe; Forlani, Francesco; Timor-Trisch, Ilan; Palacios-Jaraquemada, José; Foti, Francesca;

Minneci, Gabriella; Flacco, Maria E.; Manzoli, Lamberto; Familiari, Alessandra; Pagani, Giorgio; Scambia,

Giovanni; D'Antonio, Francesco. Diagnostic accuracy of ultrasound in detecting the depth of invasion in

women at risk of abnormally invasive placenta: A prospective longitudinal study. Acta Obstetricia et

Gynecologica Scandinavica 2018; 97.(10) s. 1219-1227.

11. Calì, Giuseppe; Timor-Trisch, Ilan E.; Palacios-Jaraquemada, Josè; Monteaugudo, Ana; Forlani, Francesco;

Minneci, Gabriella; Foti, Francesca; Buca, Danilo; Familiari, Alessandra; Scambia, Giovanni; Liberati,

Marco; D'Antonio, Francesco. Changes in ultrasonography indicators of abnormally invasive placenta

during pregnancy. International Journal of Gynecology & Obstetrics 2018; 140.(3) s. 319-325.

12. Calì, Giuseppe; Timor-Tritsch, Ilan E.; Palacios-Jaraquemada, José Miguel; Monteaugudo, Ana; Buca,

Danielo Italo Pio; Forlani, Francesco; Familiari, Alessandra; Scambia, Giovanni; Acharya, Ganesh;

D'Antonio, Francesco. Outcome of Cesarean scar pregnancy managed expectantly: systematic review and

meta-analysis. Ultrasound in Obstetrics and Gynecology 2018; 51.(2) s. 169-175.

13. Ciardulli, Andrea; D'Antonio, Francesco; Magro-Malosso, Elena R.; Manzoli, Lamberto; Anisman, Paul;

Saccone, Gabriele; Berghella, Vincenzo. Maternal steroid therapy for fetuses with second-degree immune-

mediated congenital atrioventricular block: a systematic review and meta-analysis. Acta Obstetricia et


14. D'Antonio, Francesco; Odibo, Anthony O.; Prefumo, Federico; Khalil, Asma; Buca, Danielo Italo Pio; Flacco,

Maria Elena; Liberati, Marco; Manzoli, Lamberto; Acharya, Ganesh. Weight discordance and perinatal

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mortality in twin pregnancy: systematic review and meta-analysis. Ultrasound in Obstetrics and

Gynecology 2018; 52.(1) s. 11-23.

15. D'Antonio, Francesco; Palacios-Jaraquemada, José; Timor-Trisch, Ilan; Calì, Giuseppe. Placenta accreta

spectrum disorders: Prenatal diagnosis still lacks clinical correlation. Acta Obstetricia et Gynecologica

Scandinavica 2018; 97.(7) s. 773-775.

16. D'Antonio, Francesco; Timor-Tritsch, Ilan E.; Palacios-Jaraquemada, José; Monteagudo, A; Buca, D; Forlani,

Francesco; Minneci, Gabriella; Foti, Francesca; Manzoli, Lamberto; Liberati, Marco; Acharya, Ganesh; Calì,

Giuseppe. First-trimester detection of abnormally invasive placenta in high-risk women: systematic review

and meta-analysis. Ultrasound in Obstetrics and Gynecology 2018; 51.(2) s. 176-183.

17. Dubey, Vishesh; Ahmad, Azeem; Singh, Rajwinder; Wolfson, Deanna; Basnet, Purusotam; Acharya,

Ganesh; Mehta, Dalip Singh; Ahluwalia, Balpreet Singh. Multi-modal chip-based fluorescence and

quantitative phase microscopy for studying inflammation in macrophages. Optics Express 2018; 26.(16) s.

19864-19876.

18. Familiari, Alessandra; Liberati, Marco; Lim, Philip; Pagani, Giorgio; Calì, Giuseppe; Buca, Danielo Italo Pio;

Manzoli, Lamberto; Flacco, Maria Elena; Scambia, Giovanni; D'Antonio, Francesco. Diagnostic accuracy of

magnetic resonance imaging in detecting the severity of abnormal invasive placenta: a systematic review

and meta-analysis. Acta Obstetricia et Gynecologica Scandinavica 2018; 97.(5) s. 507-520.

19. Grip, Jostein; Engstad, Rolf Einar; Skjæveland, Ingrid; Skalko-Basnet, Natasa; Isaksson, Johan; Basnet,

Purusotam; Holsæter, Ann Mari. Beta-glucan-loaded nanofiber dressing improves wound healing in

diabetic mice. European Journal of Pharmaceutical Sciences 2018; 121. s. 269-280.

20. Herling, L; Johnson, J; Ferm-Widlund, Kjerstin; Bergholm, Fredrik; Lindgren, P; Sonesson, Sven-Erik;

Acharya, Ganesh; Westgren, Magnus. Automated analysis of fetal cardiac function using color tissue

Doppler imaging. Ultrasound in Obstetrics and Gynecology 2018.

21. Johansen, Lars Thomas; Braut, Geir Sverre; Andresen, Jan Fredrik; Øian, Pål. An evaluation by the

Norwegian Health Care Supervision Authorities of events involving death or injuries in maternity care. Acta


22. Kral, Rita; Osima, Marit; Vestgaard, Roald; Richardsen, Elin; Bjørnerem, Åshild. Women with fracture,

unidentified by FRAX, but identified by cortical porosity, have a set of characteristics that contribute to

their increased fracture risk beyond high FRAX score and high cortical porosity. Bone 2018; 116. s. 259-

265.

23. Liang, Huan; Vårtun, Åse; Acharya, Ganesh. Agreement between preload reserve measured by impedance

cardiography and echocardiography during pregnancy. Archives of Gynecology and Obstetrics 2018;

298.(1) s. 59-66.

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24. Lucaroni, Francesca; Morciano, Laura; Rizzo, Giuseppe; D'Antonio, Francesco; Buonuomo, Ersilia; Palombi,

Leonardo; Arduini, Domenico. Biomarkers for predicting spontaneous preterm birth: an umbrella

systematic review. Journal of Maternal-Fetal & Neonatal Medicine 2018; 31.(6) s. 726-734.

25. Ma, Min; Zhou, Qiongjie; Xiong, Yu; Li, Bin; Li, Xiao-Tian. Preeclampsia is associated with hypermethylation

of IGF-1 promoter mediated by DNMT1. American journal of translational research 2018; 10.(1) s. 16-39.

26. Nilsen, Ingard; Rebolledo, Guillermo; Acharya, Ganesh; Leivseth, Gunnar. Mechanical oscillations

superimposed on the pelvic floor muscles during Kegel exercises reduce urine leakage in women suffering

from stress urinary incontinence: A prospective cohort study with a 2-year follow up. Acta Obstetricia et


27. Nyfløt, Lill Trine; Ellingsen, Liv; Yli, Branislava Markovic; Øian, Pål; Vangen, Siri. Maternal deaths from

hypertensive disorders: lessons learnt. Acta Obstetricia et Gynecologica Scandinavica 2018; 97.(8) s. 976-

987.

28. Nystad, Mona; Sitras, Vasilis; Nordbakken, Cecilie Valborg; Pedersen, Mona Irene; Acharya, Ganesh.

Laeverin Protein Expression in Normal and Preeclamptic Placentas using Tissue Microarray Analysis. Acta


29. Opstas, Ida S., Daria A. Popova, Ganesh Acharya, Purusotam Basnet, Balpreet S. Ahluwalia (2018) Live-cell

imaging of human spermatozoa using structured illumination microscopy. Biomedical Optic Express, 9

(12), 5939-5945.

30. Osima M, Borgen TT, Lukic M, Grimnes G, Joakimsen RM, Eriksen EF, Bjørnerem Å. Serum parathyroid

hormone is associated with increased cortical porosity of the inner transitional zone at the proximal femur

in postmenopausal women: the Tromsø Study. Osteoporos Int. 2018;29(2):421-431.

31. Pagani, Giorgio; Calì, Giuseppe; Acharya, Ganesh; Trisch, Ilan-Timor; Palacios-Jaraquemada, José Miguel;

Familiari, Alessandra; Buca, Danielo Italo Pio; Manzoli, Lamberto; Flacco, Maria Elena; Fanfani, Francesco;

Liberati, Marco; Scambia, Giovanni; D'Antonio, Francesco. Diagnostic accuracy of ultrasound in detecting

the severity of abnormally invasive placentation: a systematic review and meta-analysis. Acta Obstetricia

et Gynecologica Scandinavica 2018; 97.(1) s. 25-37

32. Skåren, Lise Hansen; Wang, Xiaofang; Bjørnerem, Åshild. Bone trait ranking in the population is not

established during antenatal growth but is robustly established in the first postnatal year. PLoS ONE 2018;

13.(9) s. 1-14

33. Sletten, Elise Thoresen; Arnes, Marit; Vereide, Anne Beate; Ørbo, Anne. Low-dose LNG-IUS as therapy for

endometrial hyperplasia. A prospective cohort pilot study. Anticancer Research 2018 ;Volum 38.(5) s.

2883-2889.

34. Ternullo, Selenia; Basnet, Purusotam; Holsæter, Ann Mari; Flaten, Gøril Eide; de Weerd, Louis; Skalko-

Basnet, Natasa. Deformable liposomes for skin therapy with human epidermal growth factor: The effect

of liposomal surface charge. European Journal of Pharmaceutical Sciences 2018; 125. s. 163-171.

https://www.ncbi.nlm.nih.gov/pubmed/29134242



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35. Wagle, Madhu; D'Antonio, Francesco; Reierth, Eirik; Basnet, Purusotam; Trovik, Tordis A; Orsini, Giovanna;

Manzoli, Lamberto; Acharya, Ganesh. Dental caries and preterm birth: a systematic review and meta-

analysis. BMJ Open 2018; 8:018556.(3) s. 1-7.

36. Widnes, Christian; Flo, Kari; Wilsgaard, Tom; Kiserud, Torvid; Acharya, Ganesh. Sex differences in umbilical

artery Doppler indices: A longitudinal study. Biology of Sex Differences 2018; 9:16. s. 1-12.

37. Zhou, Qiongjie; Wang, Qiaomei; Shen, Haiping; Zhang, Yiping; Zhang, Shikun; Li, Xiaotian; Acharya, Ganesh.

Seroepidemiological map of Toxoplasma gondii infection and associated risk factors in preconception

period in China: A nationwide cross-sectional study. Journal of obstetrics and gynaecology research 2018;

44.(6) s. 1134-1139.

38. Øian, Pål; Askeland, Olaug Margrete; Engelund, Inger Elise; Roland, Brit; Ebbing, Marta. Fødestuefødsler i

Norge 2008-10-en populasjonsbasert studie. Tidsskrift for Den norske legeforening 2018; 138.(10)s.

39. Øian P, Askeland OM, Ebbing M. Tidsskr Nor legeforen 2018 Sep 3; 138(13). Doi: 10.4045/tidsskr.18.0626.

40. Øian P. Routines for intrapartum fetal monitoring are important, but why and, more importantly, how are they used? Acta Obstet Gynecol Scand 2018 Dec 30. Doi: 10.1111/aogs.13530.

41. Bernitz S, Dalbye R, Zhang J, Eggebø TM, Frøslie KF, Olsen IC, Blix E, Øian P. The frequency of intrapartum caesarean section use with the WHO partograph versus Zhang’s guideline in the Labour Progression Study (LaPS): a multicenter cluster-randomised trial. Lancet 2018 Dec 20. Pii18)31991-3. Doi: 10.1016/S0140-6736(18)31991-3.

Published abstracts (Conference)

1. Ternullo, Selenia; Gagnat, Eivind; Schulte-Werning, Laura; Julin, Kjersti; Johannessen, Mona; Basnet,

Purusotam; Skalko-Basnet, Natasa. Curcumin-loaded liposomes-in-hydrogel for improved wound therapy:

when traditional medicine meets advanced drug delivery systems. Skin Forum 2018 Annual Meeting;

2018-06-20 - 2018-06-21.

2. Opstad, Ida Sundvor; Popova, Daria Aleksandrovna; Acharya, Ganesh; Basnet, Purusotam; Ahluwalia,

Balpreet Singh. Live-cell multi-colour 3D SIM of human spermatozoa. Focus on microscopy; 2018-03-25 -

2018-03-28.

3. Opstad, Ida Sundvor; Agarwal, Krishna; Popova, Daria Aleksandrovna; Acharya, Ganesh; Basnet,

Purusotam; Ahluwalia, Balpreet Singh. Live-cell optical nanoscopy of human spermatozoa. Norwegian

Electro-Optics Meeting; 2018-04-02 - 2018-04-04.

4. Nygaard, Ane Sigrid; Stedenfeldt, Mona; Øian, Pål; Haugstad, Gro Killi. Kvinner med langvarig

underlivssmerter. En tverrsnittstudie.. Norsk Smerteforenings årlige konferanse 2018; 2018-01-04 - 2018-

01-06.

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5. Adde, Lars; Ihlen, Espen Alexander F.; Fjørtoft, Toril Larsson; Labori, Cathrine; Loennecken, Marianne;

Møinicken, Unn inger; Rahmati, Hodjatolah; Sandstrøm, Per Gunnar; Silberg, Inger Elisabeth; Songstad,

Nils Thomas; Tiarks, Angelique; Vaagen, Randi; Øberg, Gunn Kristin; Støen, Ragnhild. Computer-based

detection of cerebral palsy (CP) in infants before 5 months’ corrected age. Pediatric Academic Societies

Meeting; 2018-05-05 - 2018-05-08.

6. Purusotam Basnet, Rajwinder Singh, Deanna L. Wolfson, Vishesh Dubey, Azeem Ahmad, Ganesh Acharya,

D. S. Mehta, Balpreet S. Ahluwalia (2018) Trophoblast and macrophage change their sub-cellular structures in

response to externally induced inflammation as shown by structured illumination microscopy and quantitative phase

microscopy. International Federation of Placenta Association (IFPA), September 21-24, Tokyo, Japan

(Placenta, 69, E28, Poster presentation).

7. Siv B. Mundal, G. B. Silva, L. M. Gierman, J. J. Rakner, Purusotam Basnet, M. Elschot, S. Bakke, L. C. V.

Thomsen, Ganesh Acharya, L. Bjørge, Ann Charlotte Iversen (2018) The role of decidual Nrf2-expression in

preeclampsia and fetal growth restriction. NFOG, Odense, Dennmark (Poster presentation).

8. Daria Popova, Vishesh Dubey, Ganesh Acharya, Dalip Singh Mehta, Balpreet S. Ahluwalia, Purusotam

Basnet (2018) Effect of oxidative stress on sperm cells investigated by label-free Quantitative Phase

Microscopy, NFOG, Odense, Dennmark (Poster presentation).

9. Ida S. Opstad, Daria A. Popova, Ganesh Acharya, Purusotam Basnet, Balpreet S. Ahluwalia (2018) Live-cell

multi-colour 3D SIM of human spermatozoa. (Oral presentation).

10. May Wenche Jøraholmen, Kristine Gravningen, Moona Johannessen, Purusotam Basnet, Ganesh Acharya,

Natasa Škalko-Basnet (2018) Liposomes-in-hydrogel for the local treatment of Chlamydia: Controlled

delivery of natural substances. 14th International Symposium on Human Chlamydial Infection (ISHCI), 1-6

July, Zeist, The Netherlands www.ishci2018.nl (Poster presentation).

11. Andreasen C, Osima M, Rognli V, Grundel DE, Elvenes J, Knutsen, G, Meknas K, Joakimsen RM, Borgen TT,

Solberg LB, Frihagen FJ, Nordsletten L, Eriksen EF, Basso T, Dahl C, Omsland TK, Bjørnerem Å.

Tromsoporosis - Adherence to a Secondary Fracture Prevention Program in Tromsø, Norway. ESCEO

Meeting, Krakow, Polan. Poster. April 19-22, 2018.

12. Andreasen C, Osima M, Rognli V, Grundel DE, Elvenes J, Knutsen, G, Meknas K, Joakimsen RM, Borgen TT, Solberg LB, Frihagen FJ, Nordsletten L, Eriksen EF, Basso T, Dahl C, Omsland TK, Bjørnerem Å. Tromsoporosis - Adherence to a Secondary Fracture Prevention Program in Tromsø, Norway. ECST. Valencia, Spain. Poster. May 25-29, 2018.

13. Andreasen C, Osima M, Rognli V, Grundel DE, Elvenes J, Knutsen, G, Meknas K, Joakimsen RM, Borgen TT, Solberg LB, Frihagen FJ, Nordsletten L, Eriksen EF, Basso T, Dahl C, Omsland TK, Bjørnerem Å. Tromsoporosis - Adherence to a Secondary Fracture Prevention Program in Tromsø, Norway. FFN. Oral. Dublin, Irland, July 5-7, 2018.

14. Andreasen C, Sikaris K, Rosen CJ, Bjørnerem Å. A Greater Proportion of the Variance in Body Fat and Bone Mineral Content is accounted for by Serum Estradiol than Follicle Stimulating Hormone (FSH), and

http://www.ishci2018.nl/

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Estradiol not FSH Contributed to the Variance in Cortical and Trabecular Microarchitecture. ASBMR Meeting, Montreal, USA. Sept 28-1 Oct 2018. Poster.

15. Andreasen C, Bjørnerem Å. Does Cortical Porosity Predict Incident Fractures in Postmenopausal Women? ASBMR Meeting, Montreal, USA. Sept 28-1 Oct 2018. Oral.

16. Leeves LT, Andreasen C, Marrable S, Glasø MU, Gaup AK, Rostad MK, Haugland NAM, Olsen IP, Bjørnerem Å. Prevalens av diabetes blant gravide har økt – mens prevalens av preeklampsi blant dem har falt: en kasus-kontroll studie i Troms og Nordland i 2004-2015. NGF Årsmøte. Oslo. 24.-26. oktober 2018. Framlegg.

4. Education

Teaching in obstetrics and gynecology (women’s health) is demanding especially since bed-side teaching must

be given in a one-to-one basis (in the obstetric out-patient clinic, the gynecological out-patient clinic, the labor

ward, gynecological and gyn-oncology units, and in the operation theater) rather than to groups of students.

Teaching for 4th year medical students in obstetrics and gynecology has been offered as the international

semester with 30-40 internatioanal students in English medium. There were 36 students participating this year

including for lectures, clinical training and practice.

Medical students (MED-3501: 5th year) have clinical practice at Department of Obstetrics and Gynecology,

UNN. Every student was given clinical practices and training in obstetrics and gynecology for 2 weeks.

Since autumn 2017, we increased the number of Seminars for the 6th year medical students. We introduced

“Test-Exams” for each of 6th year students in a one to one patient setting, followed by exam questions in

groups. This module has been very popular among the students.

The research group staffs are also involved as supervisors and mentors for master students and in the exam

committees.

5. Other activities Presentations in congresses/conferences/meetings

Invited speaker:

Ganesh Acharya:

1. Application of high resolution live cell imaging in placental research. IFPA Congress, Tokyo, Japan.

September 2018. Chair of the workshop on Placental Imaging.

2. Perinatal Mental Health: An Obstetrician´s Perspective. Key note Lecture. Global Mental Health

Conference, Oslo, Norway, 28 November 2018.

Purusotam Basnet

1. Invited Key note Speaker: Subcellular anatomy of human embryo using optical nanoscopy. ICentral

deoartment of Chemistry, Tribhuvan University, Kathmandu, Nepal, Feb 22, 2018.

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Communication to general public

1. Bjørnerem Å. Osteoporose - hva er egentlig dette og hvorfor er det viktig? Norsk

Osteoporoseforbund. Åpent møte med temaet Osteoporose – beinskjørhet; Tromsø 10. Sept 2018.

2. Andreasen C. Medisinering og behandling av osteoporose. Norsk Osteoporoseforbund. Åpent møte

med temaet Osteoporose – beinskjørhet; Tromsø 10. Sept 2018.

Referees

Kari Flo. British Journal of Obstetrics and Gynaecology (BJOG).

Ganesh Acharya, Purusotam Basnet, Åshild Bjørnerem, Francesco D’Antonio and Pål Øian: Several

international journals.

Opponents for PhD/Sensor

Ganesh Acharya: First opponent PhD thesis. Marianne Munk Sinding. Placental function estimated by

T2*-weighted magnetic resonance imaging. Alborg University, Denmark

Pål Øian. Betygskommitten. Midtveisevaluering Ph.D thesis: Pregnacies complicated by obesitas –

focus on large-for-gestational age and stillborn fetuses., Hanna Åmark, Karolinska Institutet,

Stockholm, Nov 11, 2018

Åshild Bjørnerem. Leader of the Assessment Committee of PhD thesis – Anton Kovalenko:

“Epidemiology and new opportunities of investigating risk factors for congenital malformations in

Northwest Russia: a registry-based linkage study.” Tromsø, November 12, 2018

Mona Nystad: Sensor of written examination on the subject of Molecular genetics at UiT

PhD Defence leader

Purosotam Basnet. Leader of PhD defence for Mona Nystad. Department of clinical Medicine, UiT,

Tromsø 01.04.2018

Purusoitam Basnet: Leader of PhD defence for Gro-Hilde Ulriksen in the Department of Clinical

Medicines, Faculties of Health Sciences, University of Tromsø-The Arctic University of Norway

Teaching in courses other than obstetrics and gynecology for medical students

Purusotam Basnet: Nonomedicine course (FAR-3043) intelligent Therapeutics (4 hours)

Purusotam Basnet: Legeforening organized infertilet course (1 hour)

Mona Nystad: Conducted teaching on Molecular cellebiology and genetics for IMB students (24 hours), Dentistry student (6 hours), Seminar (7 hours).

Representation to University bodies

Øystein Pedersen og Åshild Bjørnerem: Mentor i det langsgående prosjektet PROFKOM.

Åshild Bjørnerem: Delemneleder for Obsterikk og gynekologi Med-3601, delemne 6.7.

Åshild Bjørnerem: Delemneleder for Obsterikk og gynekologi Med-2520, internasjonalt semester.

Åshild Bjørnerem: medlem eksamenskommisjon Med-2520, internasjonalt semester.

Åse Vårtun: Medlem i styringsgruppa TRAVERS.

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Representation outside of University bodies

Ganesh Acharya: Board member Nordic Federation of Obstetrics and Gynecology (NFOG).

Ganesh Acharya: Chief editor Acta Obstetetricia et Gynecologica Scandinavica.

Ganesh Acharya: Medlem i Nasjonal referansegruppe for avansert fostermedisin.

Ganesh Acharya: Medlem fra USAM til Faggruppen for obstetrikk og gynekologi under det nasjonale

publiseringsutvalget i medisin.

Francesco D’Antonio: Assistant chief editor Acta Obstetetricia et Gynecologica Scandinavica.

Pål Øian: Hovedredaktør for Veileder i fødselshjelp. Den norske Legeforening/Norsk Gynekologisk

Forening.

Pål Øian: Medlem i Norsk Gynekologisk forenings NPE utvalg

Pål Øian: Medlem i NGF gruppe for maternelle dødsfall i Norge

Purusotam Basnet: 1) Associate editor of The Journal of Reproductive Biotechnology and fertility and

2) Special issue editor of International Journal of Moeculer Sciences.

Ingard Nilsen: Medlem i Styringsgruppen for rekruttering og stabilisering av gynekologer i Helse Nord.

1. members of the research group and collaborators20191303103225/Årsrapport 2018... · forekomst...

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