1 implementation science 1001 - university of newcastle · implementation science 1001 a/prof jed...
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![Page 1: 1 Implementation Science 1001 - University of Newcastle · Implementation Science 1001 A/Prof Jed Duff RN PhD FACORN University of Newcastle, School Of Nursing And Midwifery . Implementation](https://reader033.vdocuments.us/reader033/viewer/2022060918/60aad6369095e107d5365222/html5/thumbnails/1.jpg)
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1
Implementation Science 1001
A/Prof Jed Duff RN PhD FACORN
University of Newcastle, School Of Nursing And Midwifery
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Implementation research
The scientific study of methods to
promote the systematic uptake of
research findings into routine
practice to improve the quality
and effectiveness of health
services and patient care
Evidence implementation
The dynamic and iterative process
that includes the synthesis,
dissemination, exchange and
application of knowledge to
improve health and health
services
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Implementation Science
• A different type of research
• More relevant to stakeholders
• Emergent field
– Approaches still being
developed, tested
• Interface between research
and application
• Contextual
• Complex
• Multi-component programs /
policies
• Non-linear
• Transdisciplinary
• Multi-level and multi-method
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Evidence practice gap
• 30 - 40% of patients dont get treatments of proven
effectiveness
• 20 - 25% of patients get care that is not needed or potentially
harmful
• 57% of Australians are not receiving evidence-based care
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Ultimate Impact of a Magic Diet Pill
50% of Clinics Use Adoption 50%
50% of Clinicians Prescribe Adoption 25%
50% of Patients Accept Medication Reach 12.5%
50% Follow Regimen Correctly Implementation 6.2%
50% Continue TakingAfter 6 Months Maintenance 1.6%
Dissemination Step Concept % Impacted
50% of Those Taking Correctly Benefit Effectiveness 3.2%
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ComponentEvidence implementation
vsImplementation research
AimBrings about improvement
Studies improvement methods
Intervention Applies interventions Studies interventions
Design Iterative pragmatic design (more) Classical design
Protocol Flexible adaptive protocol (more) Rigid protocol
Results Context specific (more) Generalisable
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ProcessProduct Context EvaluationOutcome
Key Components of Implementation
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• Research
• Guidelines
• Evidence
• Knowledge
• Knowledge tools
• EB Products
• EB Strategies
ProcessProduct Context EvaluationOutcome
Key Components of Implementation
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• Implementation
interventions
• Change strategy
• Facilitation
• Theories
• Models
• Frameworks
ProcessProduct Context EvaluationOutcome
Key Components of Implementation
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ProcessProduct Context EvaluationOutcome
• Inner and outer
setting
• Culture
• Resources
• Leadership
• Regulation
• Accreditation
Key Components of Implementation
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ProcessProduct Context EvaluationOutcome
• Theories
• Models
• Frameworks
• Methods
• Designs
Key Components of Implementation
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ProcessProduct Context EvaluationOutcome
• System,
process,
outcome
• Individual,
organisational,
community
Key Components of Implementation
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ProcessProduct Context EvaluationOutcome
Key Components of Implementation
Theory, model, framework
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IMPLEMENTATION RESEARCH
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Broad Categories of Questions
• Process of delivery (How do we make it work?)
• Salience (Does it matter?)
• Safety (Will it do more harm than good?)
• Acceptability (Will people be willing to use it?)
• Cost-effectiveness (Is it worth buying?)
• Appropriateness (Is this the right intervention?)
• Reach (How many people exposed?)
• Intensity/dose (What is the expected/ needed strength of the intervention?)
• Satisfaction (Are stakeholders satisfied? To what degree?)
• Sustainability (Can it be continued over time?)
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NSW Health Translational Framework
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Implementation Research Framework (USA)
Replication
Adaptation
Sustainment / Scaling Up
Implementation
Effectiveness Studies
EfficacyStudies
Pre-intervention
Implementation
Research
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Implementation Outcomes
Outcome Potential measure
Impact Audit, administrative data
Acceptability Interview/ focus group, survey, take-up/ refusal
Adoption Administrative data, interview/ focus group,
observation, self-report, survey
Appropriateness Interview/ focus group, survey
Feasibility Administrative data, survey, interview
Fidelity Self-report, checklists, observation
Implementation cost Administrative data
Reach Administrative data, audit
Sustainability Audit, interviews, survey, checklists.
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Clinical effectiveness vs.
Implementation trial
Study Feature Clinical ResearchImplementation
Research
Study focus Clinical interventionImplementation
intervention/ strategy
Primary outcome Health outcomes
Processes of care,
fidelity, adoption,
reach…
Unit of randomization Patient Site, ward, clinician
Process evaluation Sometimes Always
Mixed method Sometimes Often
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Implementation Trials
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Hybrid Clinical Effectiveness/
Implementation Designs (USA)
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Example: Hybrid Type III
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Qualitative Methods in Implementation
Research
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Qualitative and Mixed Methods
• Ethnography
• Realist Evaluation
• Case Study
• Qualitative Comparative
Analysis
• Network Analysis
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Theories, Models and Frameworks
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Process Theory: Knowledge to Action
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Determinant Framework: Consolidated
Framework for Implementation Research
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Classic Theories: Theory of Diffusion
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Implementation Theories: Behaviour
Change Wheel
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Evaluation Frameworks: RE-AIM
Dimension Question
ReachHow many and what proportion of the target
population is participating in the intervention?
Effectiveness What are the effects of the intervention in eligible
patients?
AdoptionWhat is the percentage of providers participating in
the program?
Implementation Was the intervention implemented as intended?
Maintenance Is the intervention maintained after the study period?
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Change Strategies
• Audit & feedback; educational meetings and materials; opinion leaders; reminders
Individual
• Systems reengineering; redefining professional roles
Organisational
• Policy directives; outcomes based funding Regulatory
• Decision aids; patient held guidelinesPatient directed
• Disease prevention media campaignsMass media
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Align Strategies to Barriers
Barrier Consider
Anxiety about new task Simulation
Perception/ reality mismatch Audit and feedback
Relevance Flexible standardisation
Beliefs and attitudes Local consensus meetings
Logistics and timing Process redesign
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Align Strategies to Stage of Change
Awareness • Group presentation
Agreement • Consensus meeting
Adoption • Audit & feedback
Adherence • Reminders
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Address identified barrier
Evidence strength and
quality
Relative advantage
Adaptability
Trialability and measurability
Complexity Design quality Cost
Building a Change Strategy
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EVIDENCE IMPLEMENTATION
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Knowledge-to-Action
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Knowledge Creation
• Knowledge
generation
• Knowledge
synthesis
• Knowledge tools
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Knowledge Application
• Identify need
• Adapt to context
• Assess barriers
• Select
interventions
• Monitor use
• Sustain use
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Identify Knowledge Practice Gaps
• Clinical databases
• Chart audits
• Direct
observations
• Questionnaires
• Incidents
• Feedback
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Adapt Knowledge to Local Context
• Workforce
• Skill mix
• Resources
• Models of care
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Assess Barriers to Knowledge Use
• Observation
• Discussion
• Surveys
• Literature
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Common Barriers
Behaviour
Capability
- Skills
- Knowledge
Opportunity
- Time
- Resources Motivation
- Internal
- External
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Selecting Interventions
• Theoretically informed
• Mapped to barriers
• Aligned to stage of change
• Feasible, acceptable, measurable
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Implementing Interventions
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Pilot then Spread Change
All
Patients
All perioperative
POPULATION DEFINED
BY PROJECT AIM
TEST
POPULATION
TEST
POPULATION
TEST
POPULATION
Spread
Spread
Spread
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Monitor Knowledge Use
• Systems
• Processes
• Outcomes
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Sustaining Knowledge Use
• Standardisation
• Documentation
• Measurement and
review
• Training and
education
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Resources
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Resources
• Consolidated Framework for Implementation Research
(http://www.cfirguide.org/)
• NSW Health Translational Research Framework
(http://www.health.nsw.gov.au/ohmr/Pages/trgs.aspx)
• A guide to using the Theoretical Domains Framework of behaviour
change to investigate implementation problems
(https://implementationscience.biomedcentral.com/articles/10.1186/s1
3012-017-0605-9)
• Knowledge Translation (https://ktcanada.org)
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