1 diabetes in hospital prepared by [lynne gilks] [cnc diabetes education] [tamworth diabetes centre]...
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Diabetes In HospitalPrepared by [Lynne Gilks][CNC Diabetes Education]
[Tamworth Diabetes Centre]
[Nov 2010]
Diabetes & hospitalisation
Issues to consider:
Type of Diabetes
Glycaemic control during hospitalisation
Managing fasting in the diabetic patient
Use of sliding scale insulin
Lack of basal insulin
Discharge planning
Follow up
Diabetes & hospitalisation
Important to determine and document whether:
Type 1 diabetes
Type 2 diabetes
Type 2 insulin requiring
Diabetes & hospitalisation
Admission necessary the day before surgery for thorough assessment if :
Type 1 DM
Type 2 DM insulin requiring
DM that is poorly controlled
Major surgical procedures
Patient is likely to be NBM for a prolonged period pre or post operatively
Diabetes & hospitalisation
Optimal BGL prior to, during and after surgery will assist with wound healing, reduce the risk of post-operative complications (including infection) and shorten hospital time
Stress of anaesthetic and surgery tends to cause BGL to rise
An increase in diabetes treatment may be required for an extended period
Patient should be informed that medication/insulin doses should return to pre-operative doses as they recover and become more active
Monitor BLG 4 times per day or more frequently if appropriate
Diabetes & hospitalisation
Blood glucose levels as close to normal as possible improves in-hospital morbidity & mortality rates. Demonstrated strong association between hospital hyperglycaemia and adverse clinical outcomes.
Aim for blood glucose levels 5 to 10 mmol/l
Never stop insulin in a Type 1 diabetic
Avoid routine use of sliding scale insulin as this destabilises diabetes in most patients.
Sliding scale insulin should only be used in limited circumstances
Diabetes & hospitalisation
Insulin regimes should target prospective (anticipated BGL) rather than reactive retrospectively to previous BGL
It is better to adjust overall regime to prevent further rises in BGL
If at any stage diabetes management targets are not being met, contact medical team for review of patient
Diabetes & hospitalisation
Oral Hypoglycaemic agents (OHA) which are started or increased during hospitalisation generally do not work quickly enough to control hyperglycaemia
Inpatients who have adequate diabetes control and have no contraindications (patient being acutely ill or renal impairment) OHAs can be continued
An insulin/glucose infusion would be used if the patient requires insulin and is fasted for a prolonged period of time (more than 6 hrs) or patient is very unstable
Diabetes & hospitalisation
The frequency of BG monitoring needs to be assessed regularly
Notify Medical Officer if BGL is > 15 mmol/l on 2 consecutive readings or any BGL > 20 mmol/l
Check urine ketones in Type 1 patients if BGL is > 15 mmol/l or if the patient is very ill.
If ketones are present especially if large urinary ketones or blood ketones are >1.6 or ketoacidosis is suspected contact Medical Officer
Diabetes & hospitalisation
Surgery:
Anaesthetic consult.
Advice regarding insulin regimes can be obtained by contacting Endocrinologist or Physician if necessary
Metformin should be ceased 48 hrs prior to surgery
Sulphonylureas need to be withheld on the day of surgery
Daonil, because of it’s long action, may need to be withheld the night before surgery
Management determined by BGL and whether the person is eating or not
Diabetes & hospitalisation
All people with DM should have their BGL checked within 1 hr prior to going to theatre
Notify Anaesthetist if:
BGL is < 5 mmol/l
BGL is > 10 mmol/l
BGL should be done during surgery and immediately post-operatively
People with Type 1 DM are particularly at risk from ketosis. Notify Anaesthetist or Medical Officer if ketones are present in urine or blood
Diabetes & hospitalisation
Before giving insulin to a person who is fasting ensure there is an IV glucose infusion in place, that is running
Ensure optimal hydration & electrolyte balance (dehydration increases BGL)
Operate early in the day (in Type 1 DM prolonged fasting predisposes to DKA)
In patients with gastro paresis allow longer period of fasting before surgery
All patients with Type 1 DM should be receiving some insulin at all times even when NBM
Most people with Type 2 DM will usually need insulin for major surgical procedures
Diabetes & hospitalisation
Type of IV fluid given will depend on whether the person is receiving insulin, fasting or not and their BGL
Glucose infusion must be used if the patient has received insulin prior to or during surgery
Monitor BGL at least every 2 hrs- hrly if IV glucose/insulin infusion in situ
Diabetes & hospitalisation
Check BGL on arrival at recovery
Then every 4 to 6 hrs
If on IV insulin/glucose infusion then hrly
Once stable and eating -before meals
All people with Type 1 DM require checks for ketones:
At least 8 hrly
If BGL > 15 mmol/l
If vomiting or generally unwell
Diabetes & hospitalisation
Discharge planning should start at admission
Recommence anticipated discharge regime for at least 24 hrs prior to discharge
Patient should be advised of regime on discharge
Radiological Procedures
Book earliest possible appointment time to minimise problems for people with DM
Radiology Dept should be notified the patient has DM and their current treatment regime
Medication/ Insulin orders may be modified according the patient’s type of DM, medication/ insulin and time of procedure
Any dose reduction needs to be discussed with MO and the person with DM
Radiological procedures
Well controlled Type 2 DM on diet only or OHA
Omit morning dose of OHA if fasting is necessary
Metformin should be stopped 48 hrs prior to a procedure
Assess serum creatinine levels before restarting Metformin
Type 1 & 2 receiving insulin:
Individual advice based on insulin regime
Radiological procedures
BG monitoring equipment should be available
BG should be check before, during and after the procedure especially in patient feels unwell or hypoglycaemic
All patients with diabetes should bring with them:
some quick acting CHO in case of hypoglycaemic episode
Radiology Dept should have available:
Hypoglycaemia guideline, BG meter and hypo kit
Radiological procedures
Special precautions may be necessary for people having any radio contrast study which includes angiography, CT scan with enhancement, intravenous pyelography. Those most at risk:
Impaired renal function-GFR< 30ml per min
Dehydration or effective reduction in blood volume-eg CCF, Hypotension, septic shock or intensive diuretic therapy
Other nephrotoxic drugs or medications that may contribute to decreasing GFR-eg gentamicin, diuretics, ACE inhibitors, Angiotensin II receptor antagonists, NSAID, cyclo-oxygenase 2 inhibitors, cyclosporin, vancomycin, tacrolimus, amphotericin.
Radiological procedures
The following precautions may need to be considered by MO:
Stopping certain medications several days before the procedure-eg diuretics, NSAID
Hydration before, during and after the procedure
Radiological procedures
After the procedure:
Once eating and drinking recommence medication except for Metformin-check serum creatinine/GFR prior to restarting this
It may be necessary to reduce insulin dose if food intake is reduced. Discuss medication adjustment with MO or Diabetes Educator
Type 1 diabetes & insulin need
Type 1 Diabetics:
At diagnosis 80 to 90% of their beta cells have been destroyed by an autoimmune process
They become insulin deficient
Insulin deficiency results in:
-hyperglycaemic
-Osmotic diuresis leading to dehydration
-ketosis
-metabolic acidosis
-electrolyte loss
Insulin deficiency
Rapid acting
– Immediate onset, very short duration
– Novorapid, Humalog & Apidra
Short acting
-rapid onset and short duration
-Actrapid & Humulin R
Basal/bolus insulin
References
Guideline for the management of Diabetes during surgery, Diabetes Centre POW hospital
Hospitalisation, section 4 Diabetes Manual 7th edition A guide to Diabetes Management 2009
National Associations of Diabetes Centre Course for Nurses & Allied Health Professional
Significance of Hyperglycaemia for Hospitalised patients, N.Wah Cheung. Westmead Hospital