1-22 © th. cherbuliez, m.d... la i bee apimondia 09 montpellier, france

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1-22 © Th. Cherbuliez, M.D. © Th. Cherbuliez, M.D. . . LA I Bee APIMONDIA 09 APIMONDIA 09 Montpellier, Montpellier, France France

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LA I Bee

APIMONDIA 09 APIMONDIA 09 Montpellier, Montpellier,

FranceFrance

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Highlights of Highlights of Apimondia 2009Apimondia 2009

Papers offered

2009 December 062009 December 06

Th. Cherbuliez, MDTh. Cherbuliez, MD

ApitherapyApitherapy

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Categories

Papers/Posters Papers/Posters offeredoffered

Apitherapy Commission: Apitherapy Commission: 46 oral communications; 38 46 oral communications; 38 presentedpresented

Total for Apimondia: Total for Apimondia: ≈ 700 oral and posters≈ 700 oral and posters

Apitherapy Commission: Apitherapy Commission: 48 Posters48 Posters

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Apitherapy basics

10 Papers presented 10 Papers presented here here

CategoriesCategoriesReconciliation between Empirism and the Traditional Reconciliation between Empirism and the Traditional Scientific model; between two models of thinking Scientific model; between two models of thinking about “scientific” about “scientific” New findings: LAB, Propolis for Plasmodium, RJ & New findings: LAB, Propolis for Plasmodium, RJ & Propolis for type 2 diabetes, new wound dressingPropolis for type 2 diabetes, new wound dressing

Developments: Cancer, Alcoholism, Anaphylaxis and Developments: Cancer, Alcoholism, Anaphylaxis and PsoriasisPsoriasis

General developments: Propolis in China.General developments: Propolis in China.

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Linking

Basic clinical concepts in Basic clinical concepts in Green Medicine Green Medicine

Author: Roch Domerego, from BelgiumAuthor: Roch Domerego, from BelgiumVariabilityVariability

Based on 3 dimensions: 1) Multi Based on 3 dimensions: 1) Multi molecularmolecular

2) 2) Energetic Energetic

SynergySynergy

Multi-factorialMulti-factorial

3) Therapeutic 3) Therapeutic AllianceAlliance

Relation psyche-pathology-therapeutic Relation psyche-pathology-therapeutic forcesforcesRespect for all Respect for all componentscomponentsInteraction person-Interaction person-environmentenvironment

ListeningListening

Mutual adaptability-Mutual adaptability-harmony.harmony.

State-treatment State-treatment consciousnessconsciousness

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Photo

Linking Empirism of Linking Empirism of Apitherapy Apitherapy with modern with modern

Biomolecular Medecine Biomolecular Medecine Author: Eberhard Bengsch, from GermanyAuthor: Eberhard Bengsch, from Germany

Biomolecular medicine has developed much knowledge about origin, evolution and metabolic details of many diseases, biomolecular medicine explains but does not heal. Apitherapy heals but does not explain

The major pathologies of mankind remain unsolved by conventional medicine

Some 800 conditions belonging to the groups of Tumors, Cardio-vascular and Neuro-vegetative diseases, Autoimmune and Psychiatric disorders can be touched by Apitherapy products, by mechanisms poorly elucidated.

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LA Bacilus

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Antiplasmodium

Lactic Acid Bacteria in Lactic Acid Bacteria in the Beethe Bee

Authors: Tobias Olofsson & Alejandra Vasquez, from Authors: Tobias Olofsson & Alejandra Vasquez, from SwedenSwedenThey have identified a large and unique lactic acid They have identified a large and unique lactic acid bacterial flora composed of thirteen novel bacterial bacterial flora composed of thirteen novel bacterial species originating in the honey stomach. They are species originating in the honey stomach. They are potent inhibitors of human pathogens and food spoiling potent inhibitors of human pathogens and food spoiling organisms. organisms. (The bees inoculate the pollen with the bacteria as (The bees inoculate the pollen with the bacteria as they harvest it. In vitro, LAB inhibit the growth of they harvest it. In vitro, LAB inhibit the growth of bacteria in the human intestinal flora such as bacteria in the human intestinal flora such as salmonella and proteus vulgaris.) salmonella and proteus vulgaris.) These novel LAB most probably play a key role These novel LAB most probably play a key role regarding benefits when consuming bee products as regarding benefits when consuming bee products as honey, bee pollen and bee bread. honey, bee pollen and bee bread.

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RJ & Propolis for Insulin resistant diabetes

Propolis as anti-plasmodium Propolis as anti-plasmodium medicine medicine

Author: James Author: James Hutagalung, from Indonesia

Plasmodium-agent of malaria; resistance to Plasmodium-agent of malaria; resistance to antibiotics observed from1950 onantibiotics observed from1950 on

Flavonoids in Propolis, a complex of tree sap, Flavonoids in Propolis, a complex of tree sap, beeswax, sugars, can destroy the parasite in its beeswax, sugars, can destroy the parasite in its early developmental stage.early developmental stage.

In early stages of testing. In early stages of testing.

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Wound gafting

Royal Jelly and Royal Jelly and Propolis Propolis

for insulin resistance in type 2 for insulin resistance in type 2 diabetics diabetics Author: Hiromu Kawazaki, from JapanAuthor: Hiromu Kawazaki, from Japan

Studies on insulin resistance (hyperinsulinemia) in fructose-drinking rats

RJ (100 and 300 mg/kg/day, p.o.) or PPL (Brazilian propolis extract; 100 and 300 mg/kg/day, p.o.) for 8 weeks

Results: some decrease of systolic blood pressure and significant decrease of insulin serum level

Conclusion: RJ and PPL could be an effective functional food to prevent insulin resistance associated with the development of hypertension.

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Clinic of Cancer

Amnion Grafts for Amnion Grafts for Wound Wound using Honeyusing Honey

Author: Nagi Marsit, from LibyaAuthor: Nagi Marsit, from Libya

Ideal functions: Ideal functions: available, inexpensive, not available, inexpensive, not inflammatory to the wound, not antigenic, prevents inflammatory to the wound, not antigenic, prevents bacterial access to the wound, decreases evaporation bacterial access to the wound, decreases evaporation of body fluids and loss of electrolytes, good of body fluids and loss of electrolytes, good adherence to the wound, fosters granulation and rapid adherence to the wound, fosters granulation and rapid healing.healing.This is realized with the production of honey This is realized with the production of honey impregnated human amniotic membranes sterilized by impregnated human amniotic membranes sterilized by gamma rays from cobalt-60 sources. It keeps at room gamma rays from cobalt-60 sources. It keeps at room temperature without further irradiation for more temperature without further irradiation for more than four yearsthan four years.

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Table

Clinical experience with Clinical experience with Propolis Propolis for Cancer patients for Cancer patients

Author: Author: Osamu Mizukami, from Japan

Used propolis from Brazil in more than 500 advanced cancer patients over15 years. For most, quality of life improved They show slow growth to no change to disappearance of tumors

Most patients have other treatment modalities concurrently

Ethical and legal objection to having propolis as only treatment.

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Normalization of alcohol

Clinical experience with Clinical experience with Propolis Propolis for Cancer patients for Cancer patients

Propolis has

1. Direct anti-cancer effect: re-establishes apoptosis

2. Immune-enhancing effect

3. Anti-oxidant effect

4. Anti-angiogenic effect and anti cell-proliferation effect

5. Anti-inflammatory effect  

6. Anti-viral and anti-bacterial effects

7. Tissue-regenerating effect

8. Chemo-protective and synergetic effects

9. Radio-protective and synergetic effects

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Allergy w. Bee products

Normalization of Normalization of alcohol alcohol with Apitoxinwith Apitoxin

Author: Igor Krivopalov-Moscvin, from RussiaAuthor: Igor Krivopalov-Moscvin, from Russia

This is a program to get people with alcohol abuse or alcoholism, not to refrain from alcohol completely but to rehabilitate destroyed functions

Apitoxins (bee venom extract) remove the primary and secondary longings for alcohol, and normalize activity of detoxification enzymes

Results after 6 months (%) , after one year (%), after three years (%)

Alcohol abuse : 84.9 77.969.9

Alcoholism: 79.9 69.8 55.1.

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ttt of Psoriasis

Treatment of allergy to Treatment of allergy to bee products bee products with Apitherapywith Apitherapy

Author: Stefan Stangaciu, from RomaniaAuthor: Stefan Stangaciu, from Romania

The classical, allopathic, treatment of allergies The classical, allopathic, treatment of allergies implies the use of antihistaminic, corticosteroids and implies the use of antihistaminic, corticosteroids and if necessary, adrenalin if necessary, adrenalin The bioflavonoids (quercetine, chrysine, luteonin, The bioflavonoids (quercetine, chrysine, luteonin, etc.), present in propolis, bee pollen/bee bread, honey, etc.), present in propolis, bee pollen/bee bread, honey, beeswax, play a very important and useful role in the beeswax, play a very important and useful role in the prevention and treatment of allergic reactionsprevention and treatment of allergic reactionsWith a correct diet (rich in bioflavonoids), a good life With a correct diet (rich in bioflavonoids), a good life style (with enough sleep), a healthy vertebral column, style (with enough sleep), a healthy vertebral column, the regular practice of acupressure, honey massage, the regular practice of acupressure, honey massage, Shiatsu, etc, the development of the allergic reactions Shiatsu, etc, the development of the allergic reactions may be prevented or treated. may be prevented or treated.

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ttt of mucositis

Treatment of PsoriasisTreatment of Psoriasisbyby api-reflexotherapy and bee api-reflexotherapy and bee

products products Author: Author: N.Z.Khismatullina, from Russia

Goal of the study: extension of the period between acute attacks

Use of Bee venom, bee bread, pollen load, royal jelly, propolis, beeswax and apizan (extracted from chitin of bees) complex treatment of bee stinging, some api-products and peloids, some kind of balneological treatments, music- and psychotherapy After a second course of treatment 83% of patients were free of attacks. They had only common plaques. No other medication was used

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Nougat & bees

Scientific Research in Scientific Research in China China and Application of and Application of

PropolisPropolisAuthor: Lihong Chen. from ChinaAuthor: Lihong Chen. from China

Major increase of research on the functions of propolis, such as anti-bacterial, anti-inflammatory, anti-oxidation, anti-tumor and cell toxin, softening blood vessels, improving blood microcirculation, enhancing immunity, anaesthetization and promoting tissue regeneration The past decade has witnessed a tremendous boom in the use of propolis in health care products and folk medicine for treating diabetes, cardiovascular diseases, neurodegenerative diseases, and some cancers in China

The new Chinese Pharmacopoeia has included propolis in its descriptions of Apitherapy medical applications.

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Nougat stand with beesNougat stand with bees

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ENDEND

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China

Propolis and honey syrup as Propolis and honey syrup as prophylaxis prophylaxis of of oro-pharyngeal oro-pharyngeal mucositis in irradiated patients mucositis in irradiated patients

Author: Barbara Boyd, from Italy (prepared but not Author: Barbara Boyd, from Italy (prepared but not presented)presented)

Three grades of mucositis; Grade 3 often leads to interruption of the cancer treatment

Measure: take Honey-propolis syrup 5 ml 4 times a day

Results: No grade 3, milder grade 2, no treatment Results: No grade 3, milder grade 2, no treatment interruptioninterruption

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Wound w. Amnion graft

Propolis formulation to Propolis formulation to treat burnstreat burns

Author: Andrea Beretta-Silva, from ItalyAuthor: Andrea Beretta-Silva, from Italy

A formulation providing sustained delivery of a standardized propolis extract, a product that maintains its liquid state in low temperatures and provides in situ gelling property

The proposed pharmaceutical form intends to enhance patient’s comfort and acceptance, to obtain a histological well-organized skin tissue and to reduce wound healing time.

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LA I Bee

Probiotic effect of Lactic Probiotic effect of Lactic Acid Bacteria Acid Bacteria from fresh bee from fresh bee

pollen pollen Author: Patrick Author: Patrick Percie du Sert, from France

Bees collecting pollen leave the hive with nectar in their honey stomachs that contains Lactic Acid Bacteria (LAB). On their return, the pellets of pollen contain the same number of LAB as the nectar that was in their honey stomachs when they set out. The bees inoculate the pollen with the bacteria as they harvest it. LAB inhibit the growth in vitro of potentially pathogenic bacteria in the human intestinal flora such as salmonella and proteus vulgaris. LAB fresh or frozen pollen has probiotic effects which suggest possible benefits for human health and well-being.