0801connective.twinning.ppt

7/29/2019 0801Connective.twinning.ppt

1/61


2/61


3/61

Learning Objectives

To define the microstructure of connectivetissue proper

To define the microstructure of connectivetissue with special properties

To define the microstructure of supporting

connective tissue


4/61

Three fundamental components :

- cells

- protein fibers : Collagens, elastic- ground substance


5/61

Loose Connective Tissue

1. Elastic fibers

2. Collagenous fiber

3. Adipose

cells

4. Fixed macrophages(histiocytes)

5. Eosinophils

6. Lymphocytes

7. Mast cells

8. Fibroblasts

9. Collagenous fibers

10. Elastic fibers

11. Fixedmacrophages

12. Capillary containingerythrocytes

13. Cytoplasmic processes

14. Nucleus

15. Nucleolus

16. Nucleus

17. Vacuoles with

neutral red

18. Nucleus

19. Mast cell granules

I. Fibroblast II. Fixed macrophage III. Mast cell


6/61

1. Collagenousfibers

2. Fibroblastnucleus

3. Fibroblastnuclei

4. Fibroblast :cytoplasm andnucleus

5. Neutrophil

6. Lymphocyte

7. Adipose

cells

8. Nuclei ofadiposecells

9. Collagenous

fibers

10. Capillaries

11. Neutrophil

12. Lymphocytes

Loose connective tissue

Connective Tissue


7/61

4. Nuclei oftendon cells(surface view)

4. Nuclei oftendon cells

(slide view)

1. Tendon cells

2. Collagenousfibers

3. Bundle oftendon fibers

Dense regularConnective

Tissue

Dense regular connective tissue


8/61

7. Skeletalmuscle fibers(t.s)

8. Interfascicularconnectivetissue

9. Tendon cells

10.Collagenousfibers

1. Bundles oftendon fibers

2. Tendon cells(nuclei)

3. Connective

tissue betweenbundles

4. Interfascicularconnective tissue

5. Bloodvessels

6. Lamellar(Paciniancorpuscle)

Connective Tissue

Dense regular connective tissue


9/61

Dense irregular connective tissue

The component of this tissue are identical to those in dense

regular connective tissue

6. PerivascularundifferentiatedMesenchymal cell

2. Collagenousfibers (l.s)

3. Neutrophils

4. Capillaries

5. Fibroblasts

1. Bundles oftendon fibers

7. Endothelial cell8. Venule

9. Lymphocytes

10. Elastic fibers

11. Fibroblasts

Dense irregular arranged connective tissue


10/61

Connective Tissues with Special

Properties

Reticular Connective Tissue :


11/61

Elastic Tissue


12/61

Mucous Connective Tissue

This tissue has few cells and fibers distributedrandomly in the abundant ground substance

(Whartons jelly)


13/61

Adipose Tissues

The two types of adipose tissues

Unilocular adipose tissue (common,

yellow) Multilocular adipose tissue (brown)


14/61

Development of fat cells. Undifferentiated Mesenchymal cells aretransformed into lipoblasts that accumulate fat and thus give rise to mature

fat cells. When a large amount of lipid is mobilized by the body, mature

unilocular fat cells return to the lipoblast stage. Undifferentiated

mesenchymal cells also give rise to a variety of other cell types, including

fibroblasts. The mature fat cell is actually larger than shown here in relation

to the other cell types in this illustration.


15/61

also termed as White/yellow adipose tissue single fat droplet a signet-ringappearance

Unilocular Adipose Tissue


16/61

Feature :

- Brown fat

- multiple small lipid droplets in its adipocytes.

Brown adipocytes are smaller than white

adipocytes, a spherical and central nucleus,

numerous mitochondria

Distribution :

Newborns

Multilocular Adipose Tissue


17/61

Brown Adipose Tissue


18/61

Distribution of adipose tissue. In human newborn, multilocular adipose

tissue constitutes 2 5 % of the body weight and is distributed as

shown. The areas indicate multilocular adipose tissue ; shahed areas, a

mixture of multilocular and unilocular adipose tissue.


19/61


20/61

Erythrocytes


21/61

Erythrocytes


22/61

Erythrocytes


23/61

Neutrophils


24/61

Neutrophils


25/61

Neutrophils


26/61

Neutrophils


27/61

Eosinophils


28/61

Basophils


29/61

Lymphocytes


30/61

Lymphocytes


31/61

Platelets


32/61

Platelets


33/61

Hematopoiesis


34/61

Mature cell types in circulating blood


35/61


36/61

Hyaline cartilage


37/61

Elastic Cartilage


38/61

Fibro Cartilage


39/61

Perichondrium


40/61


41/61

Composed of :

Bone Matrix

Cells : Osteocytes

Osteoblasts

Osteoclasts

Osteoprogenitor


42/61

Bone matrix (cont.)

INORGANICMATTER

Calcium Phosphate Bicarbonate

Citrate

Magnesium

Potassium Sodium

ORGANIC MATTER

Collagen Fibers

Amorphous Groundsubstance :

Chondroitin 4-sulfate

Chondroitin 6-sulfate

Keratan Sulfate


43/61

Cells

Osteoblast

Osteoclast

Osteocyte

Mesenchyme

Bone Matrix

Newly formed matrix


44/61

Endochondral Ossification

Resting zone

Proliferative zone

Hypertrophic cartilage

zone Calcified zone

Ossification zone


45/61

Long bone


46/61

Thick ground section of tibia illustrating the

cortical compact bone and the lattice of

trabeculae of cancellous bone

Compact Bone


47/61

Compact Bone


48/61

Interstitial

lamellae

Inner

Circumferentiallamellae

Haversian system

(osteon)

Outercircumferential

lamellae

Volkmanns canal

PeriosteumEndosteum Haversian canal

Compact Bone


49/61

Compact Bone


50/61

Haversian system (a part)

Compact Bone


51/61

Compact Bone

Compact Bone


52/61

Compact Bone


53/61

Muscular Insertion Into Bone

Active Periosteum


54/61

Active Periosteum

Active Periosteum


55/61

Active Periosteum



56/61


Epiphysis


57/61

Epiphysis

E i h i l G th Pl t


58/61

Epiphysial Growth Plate

E i h i l G th Pl t


59/61

Epiphysial Growth Plate

Tendon


60/61

Tendon


61/61

THANK YOU

0801connective.twinning.ppt

Documents