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TRANSCRIPT
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IV
2011
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: . , - . , -
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ISBN 978-99929-64-53-7
DDC641.5517M-695
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, , , , , , , . 5 IV 2010 , , , , , .
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.......................................................................................................................................... 3 .......................................................................................................................................... 4 ..................................................................................................... 5 .............................................................................................................................................. 8 ............................................................................................................. 10 ....................................................................................................................... 11 ............................................................................................................................ 14 ........................................................................................................ 18 ......................................................................................................... 19 .................................................................................................. 21.
1.1. , ................................231.2. , .................................24
1.2.1. () ..................................................................................241.2.2. , ...............................................................................251.2.3. ..............................................................................................261.2.4. ............................................................................................. 261.2.5. ..................... 26
1.3. ..............................................27.
2.1. ....................................................282.2. ..................................................................................................282.3. ...................................................................................................282.4. .............................................................................................292.5. ..................................................................................292.6. .......................................................................................29
. 3.1. .....................................................................................................303.2. ..........................................................303.3. , .........................................31
3.3.1. ........................................................................................313.3.2. .............................................................................323.3.3. ..........................................................33
3.4. , .......................................................343.5. .........................................................................343.6. ................................................................................ 34
3.6.1. .............................................................................343.6.2. ...................................................................................353.6.3. ...............................................................................................373.6.4. .....................................................................373.6.5. .............................................................................373.6.6. ................................37
. 4.1. ...............................38
4.1.1. .........................................................................................38 4.1.2. ........................................................................39
4.1.2.1. ............................................................................................... 404.1.2.2. ................................................................................... 414.1.2.3. ................................................ 424.1.2.4. ......................................... 444.1.2.5. ........................................ 45
4.1.3. ............................................................484.1.3.1. ....................................................................................... 484.1.3.2. ....................................................................................... 50
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4.1.3.3. ................................................................ 514.1.3.4. - ........................................ 514.1.3.5. ................................................................... 53
4.1.4. , .......................564.1.4.1. ....................................... 564.1.4.2. ................................................................................ 584.1.4.3. ..................................................................... 59
4.1.5. ..........................................................624.1.5.1. ................................................................................ 624.1.5.2. ............................................................................. 64
4.1.6. , ..................................................664.1.7. .........................................................................68
4.1.7.1. ...................................................................... 684.1.7.2. ..................................................................... 70
4.1.8. ...................764.2. 7-11 ............................................80
4.2.1. ..........................................................................................804.2.2. ......................................................................................804.2.3. 7-11 ...........................................844.2.4. , ................................................864.2.5. ...........................................................................................894.2.6. .............................................................................90
4.3. .................................944.3.1. , .......................................................944.3.2. ........................................................................954.3.3. .....................................................................................................974.3.4. , ...................1004.3.5. .................................................................................................1024.3.6. ............................................................................................1034.3.7. ........................................1054.3.8. ....................................................110
4.4 ..........................1194.4.1. , .....................................................1194.4.2. ..................................................................................1214.4.3. ........................................................................123
4.4.3.1. ..................................................................................... 1234.4.3.2. ..................................................................................... 125
4.4.4. ...........................................................................................1274.4.5. , ...............................1284.4.6. ............................................................................................1314.4.7. ...................................1324.4.8. ...........................135
4.5. .....................................................1474.5.1. , .....................................................1474.5.2. () .........................................................................1494.5.3 ............................................................................................1514.5.4 ......................................................151
4.6 .......................................................1624.6.1 .............................................................1624.6.2 ...........................................................165
. .............................................................................................................169. .......................................................................................................................172 ..............................................................................................................................173
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34
510- . : 490-510. : 20-250. Hospitex Diagnostics 0.17/ .
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-
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( 12).
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0-59 706
2-59 633
6-59 433
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20
40
60
80
100
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0-59 (98.4%, 95% 97.0-99.2), 1 99.3% (95% 97.1-99.8) . 693 13 680 .
5.7% (95% 4.0-8.2) .
6.57.6
5.3 5.2 4.6
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(n=139)
(n=144)
(n=113) (n=154)
(n=130)(n=130)
15. , 0-59 , ( 15).
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0
1
2
3
4
5
6
7
8
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12-23 (n=175)
24-35 (n=140)
36-47 (n=112)
48-59 (n=87)
, 16. ,
( 16). 5.2% (95% 3.1-8.5), 6.3% (95% 4.0-9.8) . .
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-
45
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(31.1%)- , , 42 (23.3%) , .
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55%
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%
17.
2 , . ( )- . , , .
- . 5 10 . 10 . 10 . .
-
46
- 15.6 . . , 33.1 . - 43 . , , 20 . .
- - , . , 2 5 . - .
, . , . , . IV (6.7%, 95%CI 4.8-9.1) - 2005 (9.6%, 95% )- .
- 2006 Z . : (), - , . 6-59 .
1.73.7
0.6 1.3
12.6 12.5
6.7 5.7
2624.6
19.6
13.3
0
5
10
15
20
25
30
1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011
Wasting Underweight Stunting
18. - ,
- . 1999 - 2004 ( 18). . , III - /- (1995 )- 2006 - , . - 38- . 2004 6-59 , 0-59 . IV 0-5 ( 20).
-
47
20. - ,
(Z
-
48
4.1.3.
4.1.3.1.
2-59 663 . 19- .
6
0
5
10
15
20
25
30
5 6 7 8 9 10 11 12 13 14
()
, /
19. 2-59 6, /-
2-59 28.5% (95% 24.2-33.2) /P=0.001/. 0.4% (95% 0.1-1.3) , 11.3% (95% 8.2-15.4) , 16.7% (95% 13.3-20.9) ( 20).
20. 2-59 ,
. , , ( 21).
- ,0.4%
- ,11.3%
-,
16.7%
-71.5%
6
-
49
21. 2-59 , ,
95% 95% 95% 95%
139 0.7 0.1-5.2 15.1 9.1-23.9 19.4 13.6-27.0 35.3 25.8-46.0
143 0.7 0.1-5.1 11.9 6.9-19.7 18.2 11.8-27.0 30.8 21.8-41.5
113 0.9 0.1-6.1 9.7 4.8-18.7 15 9.7-22.6 25.7 18.1-35.0
151 0,0 - 11.3 7.6-16.4 13.9 9.0-20.9 25.2 17.9-34.2
117 0,0 - 10.3 4.6-21.2 16.2 9.7-25.9 26.5 18.7-36.2
298 0.2 0.0-1.3 11.2 6.7-17.9 15.6 10.8-21.8 26.9 21.0-33.7
365 0.7 0.2-2.9 11.6 8.1-16.3 18.4 14.0-23.6 30.7 24.9-37.1
( 21).
, (2=79.4,
-
50
. 2-23 24-59 . , ( 22).
4.1.3.2.
6-59 524 . 89 (15.7%) 2 (0.3%) . 91 433 .
22. 6-59
21.4% (95% 24.8-31.9) ( 22)
24.4 21.0 21.226.9
19.6
05
10152025303540
(n=86)
(n=81)
(n=66)
(n=108)
(n=92)
23. 6-59 ,
( 23).
, , ( 23).
23. 6-59 , ,
(
-
51
, . 24-59 . ( 23).
4.1.3.3.
, 433 , , ( ) ( 24).
24. 6-59
(5.0%) . . 20.9%, 21.6% .
7.6% (95% 3.3-16.3), 7.0% (95% 2.6-17.4), 4.6% (95% 1.8-11.6), 3.7% (95% 1.2-10.5), 4.3% (95% 1.8-10.2) . 6-59 5.4% (95% 1.2-10.5), 4.4% (95% 2.3-8.6) .
6.3% 24-59 (4.2%) 1.6 (RR=1.6 /1.6-6.2/, 2=5.8, =0.01). 18-23 8.3%, 24-29 7.5%, 12-17 6.3% (2=139.9, < 0.001).
6.8% (3.2%) 1.9 .
4.1.3.4. -
7-45 25 (3.3%, 95% 2.0-5.4) 12 2 2.8%, 2-4 4.2% (2=5.7, =0.05). 51.2% , 37.2% 11.5%- . 69.9%- .
6-59 6 ( 24).
+, +, 5.0%
-, +, 16.4%
-, -, 59.5%
+, - , 19.1%
-
52
24. - , ,
- >=60 95% 95%
6-23
46 32 69.6 47.5-85.3 5 10.9 4.7-23.2
56 36 64.3 47.8-77.9 8 14.3 6.6-28.2
54 22 40.7 26.3-56.9 6 11.1 5.6-20.9
64 24 37.5 21.9-56.2 5 7.8 3.5-16.5
50 23 46.0 31.2-61.6 7 14.0 6.6-27.4
270 137 51.0 42.9-59.1 31 12.6 8.5-18.324-59
86 30 34.9 24.6-46.8 1 1.2 0.2-7.9
75 25 33.3 23.1-45.4 4 5.3 1.6-16.5
49 11 22.4 10.6-41.4 3 6.1 1.9-18.2
74 23 31.1 18.4-47.4 5 6.8 3.0-14.6
71 14 19.7 11.2-32.3 1 1.4 0.2-9.0
355 103 26.5 21.1-32.8 14 3.3 1.8-6.1
, 6-23 . 2008 190, 2009 321 6-23 . 6-23 51.0% 6 . 60 .
, . 60 . ( 24). 24-59 6 . 53.3% (95% 45.0-61.4)- , 39.3% (95% 31.2-48.0)- 2.7% (95% 0.7-9.8)- , 2.6% (95% 1.1-6.3)- , 1.7% (95% 0.5-5.6)- . 93.5% (95% 86.6-96.9)- 6.1% (95% 2.8-13.1)- .
- 58.5% (95% 49.1-67.3) / , 41.2% (95% 31.3-52.0) / , 1.4% (95% 0.4-4.9) , 1.0% (95% 0.3-3.0) / , 2.5% (95% 0.9-6.7) , 5.9% (95% 3.3-10.2) .
6 60 , - .
76.6% .
-
53
4.1.3.5.
, , , . 14.8% (95% 12.0-18.2)- 1-2 (2.1%, 95% 0.7-5.7) , ( 25).
25.
(n=703) Hb -
95% 95%
104 14.8 12.0-18.2 102 17 24.2 15.2-36.3 590 83.1 78.8-86.7 551 170 29.0 24.4-34.0 9 2.1 0.7-5.7 8 3 40.2 13.9-73.6 78 10.4 7.8- 13.7 77 13 28.5 16.7-44.2
28 4.2 2.7- 6.4 27 4 18.7 6.6-43.1
10 1.9 0.8- 4.2 9 1 7.7 1.1-39.2
8 1.3 0.6- 2.8 8 3 33.3 11.8-65.1
. , 28.5-33.3% . 40%- . .
13.3% (95% 8.1-21.3), 16.6% (95% 13.3-20.5)- ( 26).
26.
-
, 95%
-
19011.1
(6.1-19.2)2.9
(0.9-8.7)0.5
(0.1-3.6)1.7
(0.5-5.1)84.0
(74.1-90.5)2.7
(0.5-12.6)
47111.0
(8.2-14.7)1.9
(3.1-7.8)2.4
(1.0-5.8)1.3
(0.5-3.2)81.8
(77.2-85.7)1.6
(0.6-4.1)
.
8.0% (95% 5.4-11.6) , 1.8% (95% 0.9-3.3) . 61 94.9% (95% 85.8-98.3)- / .
23.4%, 28.8% . 7.1% (95% 3.3-14.4), 9.2% (95% 6.0-13.9) .
-
54
:
- 2-59 28.5% . , III (21.4%) (RR=1.3; 95% 1.1-1.6) .
6-59 , - 2001 . 6-59 22.8% (95% 18.6 27.6) . III . 6-23 IV 35.4% (33.4%) , .
48.5
31.6
21.422.828.5
41 34
22.321.4
0
10
20
30
40
50
60
1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011
2010
25. 6-59
II (1999 ) III (2004 ) IV 2004 ( 25).
(98.6%) . . . , , .
2 , 24-59 . , , , , 2-5 . . , . 6 , , , , - , . , 6-11 44.4%, 12-17 46.9% (
-
55
) . , . 6-23 . , .
25- II (1999 ) III (22.3%, 2004 ) , IV (21.4%)- 2004 .
, 5 . , III 44.4%, 18.0% (RR=2.4; 95% 1.7-3.5). , 5 44% . , 2001 (63%) (19%)- . IV . 1999 . , , .
, 6-23 - . - 5 3 , 6-23 60 2 . . 6-23 . - . - . - , , - , .
2004 . 6 , . , . - , , , . -, - , . , .
-
56
: 1. 28.5% -
- . 2. 2-5,
6-11, 12-17 ( ) .
3. (21.4%) .4. ,
, , , .
4.1.4. ,
4.1.4.1.
31% , , 19.5%- , 9.4%- , 2.8%- , 0.8%- , 9.4% , 18.3%- 7.4% , 11.8% , 9.5%- , 3% , 5.4% , 0.2% , 15.7% , 9.6% , 25.6%- , 0.9%- 6.6%- (: 2).
(95% 7.4-11.8), (95% 14.1-23.3), (95% 8.7-16.0), (95% 12.7-19.2), (95% 6.7-13.6), (95% 21.2-29.7) 5 , , , (: 2).
:
, , (49.2%, 95% 40.3-58.2 40.5%, 95% 31.7-50.0) , (36.6%, 95% 28.5-45.5 26.3%, 95% 19.2-34.8), (5.9%, 95% 2.7-12.4 4.5%, 95% 2.0-9.7) 0-11 12-23 ,
(31.6%, 95% 24.2-40.1) 0-11 , (16.1%, 95% 9.0-27.2 10.2%, 95% 5.7-17.6),
(25.3%, 95% 17.5-34.9 20.1%, 95% 13.6-28.6), (11.7%, 95% 7.5-17.7 9.8%, 95% 5.3-17.2) 12-23 24-35 ,
(6.9%, 95% 3.7-12.5), (10.0%, 95% 5.6-17.0) (25.5%, 95% 18.6-33.9) 12-23 ,
(23.0%, 95% 14.9-33.8) 24-35 , (14.1%, 95% 8.7-22.1 15.8%, 95% 9.7-24.6),
(17.0%, 95% 10.3-26.6 14.1%, 95% 7.7-24.5), (34.4%, 95% 25.6-44.4 39.7%, 95% 27.6-53.2), (1.5%, 95% 0.5-4.2 1.6%, 95% 0.2-10.6) 24-35 36-47 ,
(0.5%, 95% 0.1-3.8) 36-47 .
12-23 19.1% (95% 12.0-29.0), 24-35 5.1% (95% 2.3-11.0)- (: 3).
55.0% (95% 49.5-60.5) .
-
57
59.1 54.169.2
46.7 50.4
0
10
20
30
40
50
60
70
80
90
(n=149)
(n=148)
(n=117)
(n=158)
(n=133)
26. ,
0-59 , . , ( 26).
27. ,
95%
325 171 51.7 43.6-59.7
380 219 59.8 53.3-66.0
( 27).
( 27).
46.664.7 55.4 56.6 46.9
0
20
40
60
80
0-11 (n=168)
12-23 (n=182)
24-35 (n=145)
36-47 (n=116)
48-59 (n=94)
,
27. ,
12-23 , .
60.8% (95% 53.2-67.8), 49.2% (95% 42.7-55.7) (p
-
58
4.1.4.2.
6-59 524 25 (25[]) , .
21.8% (95% 16.4-28.4) , 20.6% (95% 16.8-25.0) .
28. , ,
(25[OH]
-
59
4.1.4.3.
2009 10 , 7-10 .
179 27.4% (95% 55.4-72.9) 7-10 , 457 (70%) , 17 (2.6%) .
30. ,
95% (50000 ) 112 60.9 49.6-71.2 (50000 ) 1 0.5 0.1-3.4 () 43 24.5 15.9-35.7 8 4.8 1.7-13.1 *
8 4.4 1.8-10.1
*
3 1.3 0.3-5.9
4 3.7 1.4-9.4
66.6% (95% 54.5-76.8) (50000)- ( 30).
29.2
1715.5
3.4
11.4
1.7
8.5
2.8 2.4
8.1
0
5
10
15
20
25
30
1 2 3 4 5 6 7 8 9 x*
*- 28. ,
61.7% 1-3 1 ( 28).
-
60
31.
2009 10- 2010 8-
, * **-
1 50000 34 28.4 166.6 8.3-16.7
2 100000 19 18.6 333.3 16.7-33.3
3 150000 14 14.1 500 25-50
4 200000 5 3.7 666.6 33.3-66.7
5 250000 15 11.1 833.3 41.7-83.3
6 300000 2 1.9 1000 150-100
7 350000 9 8.4 1166.6 58.3-116.6
8 400000 3 3.1 1333.3 66.7-133.3
10 500000 3 2.6 1666.6 83.3-166.6
8 8.8%
*- 10 300 ** - 1000-2000 - .
. , 1- 16.7%, 1- 8.3%- . 7 (350000 ) 8.1% ( 31).
( 32).
32. ,
,
,
,
, *
**-
8 4.4 200000 1000 201000 670 33.5-67
3 1.3 200000
500-7500 200500 207500
668-69066.8-69.033.4-34.5
*- 10 300 ** - 1000-2000 - .
10 .
23.5 29.935.6
13.927.1
0
10
20
30
40
50
29. (2009 10 ),
-
61
, . ( 29).
23.1% (95% 17.1-30.5), 18.8% (95% 11.1-30.2) .
. 5 . , , 2004 III , , , , , .
, , , , , 12 , , , , , , , , , 12-35 x III .
. , .
- 2000-2003 , 37.1%, 30.5%, 41% , 49.1% , . , , , /., 2005/.
. , , .
. 5 x III . 5 , . . . , , .
2- 2 . 5 .
-
62
. III 2 . , . , 10 , 166 , 1- 16.7%, 1- 8.3%- . 50 000 7 350 000 8.4% . , . III . 2 .
3 III . , .
:1. .2.
.
3. 21.8% , 20.6% .
4. 48-59 .
5. , .
6. .
4.1.5.
4.1.5.1.
6-59 524 ()- . 89 (15.7%), 2 (0.3%), 91 433 ()- .
30. 6-59 ,
=0.35-0.69
/ , 30.8%
=
-
63
32.4% (95% 26.6-38.7) , ( 30).
( 31).
40.725.9
16.7
37.1 37
0
10
20
30
40
50
60
31. ,
, , , .
33. ,
(
-
64
34. ,
(
-
65
0-5 . . 6-11 . 30 54-59 ( 34).
87.0
63.3
82.6
94.0 96.798.7 98.7
89.994.7
90.6
13.0
34.8
17.46.0 1.5 1.3 1.3 10.1 9.41.9 1.8
5.3
0
10
20
30
40
50
60
70
80
90
100
0-5 6-11 12-17 18-23 24-29 30-35 36-41 42-47 48-53 54-59,
87.0
63.3
82.6
94.0 96.798.7 98.7
89.9
94.790.6
35. ,
0-5 8 100000 , 200000 . 6-11 53 34.8% 100000 63.3% 2 200000 ( 35). , 63.8% , 35%- .
- (2006)- 3 33.0% ( - 0.7/- )- . 100000 -, 200000- 2000 /74 7- 6-11 (100000 ) 1 , 12-59 (200000 ) 2 5 11- .
50000- 2000 . 2006 3.7%- 0.9%- .
:
1. 5 32.2% .
2. .
3. , , , .
7 , ,
-
66
4.1.6. ,
( 35).
35.
95%
85.2 68.6-93.8
-
67
. 59- :
, , ,
, , ,
, , , , , , ,
, ,
, , .
(60.6%), (7.8%) . 8.2% .
36.8% . 20.4% .
(33.8% 52.6% , )- . 31.9%, 34.8% . 32.4% , 47.8% .
. , , , , , , . .
1. .2.
.3. .
-
68
4.1.7.
4.1.7.1.
( 1 ) 0-23 350 85.5% (95% 80.5-89.4) 1 ( 36).
36. ,
95% 63 59 93.7 84.2-97.6
72 64 88.9 77.8-94.8
69 56 81.2 72.1-87.8
84 69 82.1 72.0-89.2
62 52 83.9 72.1-91.3
1 , ( 13). 1 , ( 84.9% (95% 74.2-91.7); 86.0% (95% 81.0-89.8)) . (0-11 86.0% (95% 77.6-91.6); 12-23 85.1% (95% 79.3-89.5)) .
0-23 98.2% (95% 96.3-99.1) . 0-23 98.4% (95% 88.6-99.8), 98.6% (95% 90.5-99.8), 94.2% (95% 86.6-97.6), 97.6% (95% 91.3-99.4) 0-23 .
0-23 78.6% (95% 73.1-83.3) . .
37. 0 23 ,
95% 59 93.7 84.5-97.6
59 80.8 69.0-88.9
52 75.7 64.9-83.5
65 77.4 66.3-85.6
46 74.2 62.2-83.4
0-23 ( 37). 0-23 80.2% (95% 73.3-85.6), 77.5% (95% 69.2-84.1) .
0-5 98.0% (95% 91.2-99.6), 6-11 89.1% (95% 74.5-95.8), 12-17 73.1% (95% 62.2-81.7), 18-23 57.8% (95% 47.2-67.6) 12-23 .
-
69
6-23 . 6-23 73.1% (95% 66.5-78.9) .
91.3 76.8 68.5 71.9 68
0
20
40
60
80
100
36. 6-23 ,
6-23 ( 36).
6-23 71.5% (95% 61.6-79.7), 75.5% (95% 67.3-82.2) .
: 0-5 71.3% (95% 55.8-81.2) .
76.5 64.793.6
55.1 66.7
0
20
40
60
80
100
37. ,
37- 0-5 ( 10). 0-5 69.1% (95% 50.6-83.0), 74.2% (95% 57.7-85.9) .
, 0-1 98% (95% 87.2-99.7), 2-3 85.8% (95% 67.8-94.6), 4-5 46.7% (95% 29.2-65.1) . .
: 12-15 74.0% (95% 60.4-84.1) .
100.081.8
65.091.7
68.8
0
20
40
60
80
100
38. ,
-
70
38- , , , . 70.2% (95% 52.1-83.6), 81.1% (95% 59.8-99.5) . . : 20-23 54.6% (95% 39.6-68.8) .
77.863.6 53.8
23.150.0
0
20
40
60
80
39. ,
(95% 44.2-93.9) (95% 27.9-88.8) 60 , ( 39). 52.0% (95% 31.0-72.3), 57.3% (95% 36.9-75.5) .
, - 24 . 24-59 23.6% (95% 18.6-29.5) . , 24-35 34.8% (95% 25.3-45.7), 36-47 21.7% (95% 14.1-32.1), 48-59 8.5% (95% 4.4-15.8) .
: (median) :
0-59 14.1 0-35 12.8 .
4.1.4.1.
0-5 : 0-5 28.7% (95% 18.8-41.2)- , ( , ), . 0-5 25.6% (95% 16.0-38.2) , , .
, , ( , ), 0-5 . :
, 2.0% (95% 0.4-8.3)- , 6.6% (95% 2.9-14.5)- , , 11.6% (95% 5.4-23.3)- , 15.3% (8.6-25.7)- , ,
, 6.9% (95% 2.4-18.1)- , 7.8% (95% 3.4-16.7)- , 7.5% (95% 2.9-18.1)- , 1.4% (95% 0.2-10.1)- / , 2.7% (95% 0.3-17.8)- , 1.4% (95% 0.2-10.1)- 1.6% (95% 0.4-6.5)- (), 1.4% (95% 0.2-10.1)- .
6-23 : 6-23 80.8%
-
71
(95% 73.6-86.3) - .
67.492.9 92.2
41.3
82.0
0
20
40
60
80
100
40. 6-23 ,
6-23 , , , , . 6-23 , , (
-
72
39. , 6-23 ,
,
95%
112 80.4 60.1-91.8
115 78.6 63.5-88.6
83 79.6 66.0-88.7
99 68.7 53.3-80.9
86 72.0 60.3-81.4
(72%), (68.7%) , 3.6-6.9%- ( 39). 6-23 68.3% (95% 59.6-75.9), 86.4% (95% 79.5-91.2) , , . , 6-11 68.2% (95% 55.4-78.8), 12-17 80.4% (95% 71.1-87.2), 18-23 76.5% (95% 66.4-84.3) , . , .
48.7% (95% 37.9-59.5) , , , .
6-23 92.2% (95% 86.9-95.4) (p
-
73
41. 6-23 ,
,
95% 31 21.7 9.7-41.8
21 12.5 5.2-27.0
33 35.2 21.5-51.9
24 10.9 5.2-21.6
81 54.0 37.7-69.5
6-23 . . , , , ( 41).
6-23 44.5% (95% 33.6-56.0), 16.5% (95% 9.5-27.1) . , . 6-11 25.4% (95% 16.1-37.5), 12-17 32.3% (95% 21.9-44.9), 18-23 42.1% (95% 29.7-55.6) , .
51.9% (95% 41.6-62.1) , .
6-23 47.1% (95% 40.7-53.6) , , , , , , , . , 6-23 ( 42).
42. , 6-23 ,
,
95%
18 13.0 6.9-23.3
50 53.6 39.8-66.8
66 70.4 57.3-80.8
54 31.2 21.2-43.5
72 46.0 33.6-58.9
, , . 6-23 48.8% (95% 39.7-57.9), 44.6% (95% 35.6-53.9) , .
6-11 31.7% (95% 22.3-43.0), 12-17 53.1% (95% 42.2-63.7), 18-23 54.4% (95% 42.6-65.6) , .
4 6-23 : 6-23 52.1% (95% 45.3-58.8) 4 .
-
74
43. 4 6-23 ,
4
95%
46 12 26.1 14.8-41.8
56 28 50.0 35.3-64.7
52 33 63.5 49.3-75.6
64 15 23.4 15.2-34.4
50 32 64.0 50.5-75.6
4 6-23 . 4 6-23 , , ( 43).
4 6-11 32.4% (95% 21.4-45.9), 12-17 62.9% (95% 53.3-71.6), 18-23 57.3% (95% 45.6-68.3) .
37.4% (95% 30.3-45.1), 48.7% (95% 37.9-59.5), 51.6% (95% 43.2-59.9) - 4 .
6-23 :
44.
6-23
95% 61 25.1 17.9 - 33.9
14 4.8 2.6 - 8.7
144 51.2 43.7 - 58.6
138 54.7 48.0 - 61.3
/ 19 9.0 5.1 - 15.5
/ 27 10.7 7.1 - 15.7
206 78.5 72.8 - 83.3
14 5.8 3.1 - 10.7
2 0.8 0.1 - 5.7
: 4 0.9 0.3 - 2.6
6-23 78.5%- . , , ( 44).
: 6-23 70.0% (95% 63.2-76.1) .
-
75
82.6 71.455.6 56.2
76.0
0
20
40
60
80
100
41. 6-23 ,
6-23 , , , . 6-23 ( 41).
6-23 76.4% (95% 66.1-84.4), 60.4% (95% 52.9-67.5) .
53.8% (95% 44.4-63.0), 33.3% (95% 25.2-42.6), 34.5% (95% 23.8-47.0) .
- 2007 - , - . , , . . , . , 2005 , , - 2010 . II (30 93.4%) III (1 83.5%)- . - 2005 .
2005 ( -83.2%, -64.5%)- .
- 2005 73.8%, 54.7%, 90.0% 93.7%, 76.5%, 100% - , , .
. , , 2010 ( - 26.3%, -41.7%)- .
-
76
, , .
, , , , , .
1. 85.5 1
.2. 71.3 ,
74.0%, 54.6 . 3. 6 28.7%
.4. 6-23 ,
. 5. - 3-4
. . 6. ,
, .
4.1.8
701 84.8% , 8.0% , 3.6% .
: 43.3% , ( 45).
45. , ,
95% 71 47.7 35.1-60.5
86 58.5 46.8-69.3
32 27.1 17.4-39.6
36 23.2 15.9-32.7
58 43.9 35.1-53.2
.
, 82.4% (95% 74.2-88.4), 65.1% (95% 57.2-72.3) ( 6 , )- (p
-
77
, , 69.2% (95% 44.6-86.2) 44.0% (95% 24.4-65.7) .
. (46.7%, 95% 41.1-52.1) , .
, , ( 46).
46. , ,
95% 68 45.6 33.3-58.5
90 61.2 50.7-70.8
47 39.8 30.2-50.3
29 18.7 12.9-26.4
63 47.7 36.3-59.4
7.3% 1-2 , 42.7% 3 , 21.8% 4 , 10.8% 5 ( 42).
42.
, , 43.0% (95% 34.8-51.5), 30.5% (95% 24.7-36.9) 3-5 (p
-
78
, : 47.8% (95% 41.1-54.6) , 38.7% (95% 33.0-44.7) , 22.4% (95% 17.2-28.6) , 2.2% (95% 1.1-4.4) . 10.8% , 7.4% . , , .
12.9% (95% 9.9-16.7) , 3.9% (95% 2.0-7.6) , 6.0% (95% 3.8-9.2) . 18.1% (95% 13.8-23.6) , 5.5% (95% 3.4-8.5) , 7.4% (95% 4.9-11.0) . (p
-
79
50 , , .
, , , 2 , , . : , , , , , , , . : 4 , 11.8% , 1.3% , 5.3% 19.1% , 1.8% , 5.8% .
, 45.3% - , , -2010 (44.3%) .
(2002) , , -2010 , , , , .
, , , , , , , .
1. , 46.7 .
2. , , 2 . 2 .
3. , , .
-
80
4.2 7 11
4.2.1
() , , , , , . , , 711 .
711 , 21 78 , 8 125 1207 . 53.7% (95% 50.2-57.1) , 46.3% (95% 42.9-49.8) ( 48).
48. 7 11 , ,
,
7 8 9 10 11
oo oo oo oo oo oo
137 55.3 147 52.5 152 53.8 163 53.9 40 49.7 641 53.5
114 44.7 124 47.5 130 46.2 150 46.1 48 503 566 46.5
11 (7.9%, 95% 5.8-10.6), 21.9% - 25.8% .
, (: 4, 43).
0%
20%
40%
60%
80%
100%7 8 9 10 11
43. 7 11 ,
711 , , . , , , . 1120 , .
4.2.2
711 1206 , , , . 27.7 (95% 27.1-28.2) 129.2 (95% 128.4-130.0) ( 49).
-
81
49. 7 11 , ,
() ()
95% 95%
226 25.6 24.7-26.5 226 126.4 124.8-127.9 241 27.1 26.1-28.0 240 128.9 127.2-130.4 239 27.3 26.4-28.1 239 129.3 128.0-130.6 255 26.0 25.3-26.6 254 127.5 126.1-128.7 245 29.1 27.9-30.3 244 130.5 128.9-132.1
711 , .
16.4 (95% 16.1-16.6) . 711 (: 5, 44).
15.9 16.2 16.2 15.9
16.9
14.5
15
15.5
16
16.5
17
17.5
18
44. 7 11 ,
16.6 (95% 16.2-16.9), 16.0 (95% 15.8-16.2) .
. , , - 711 ( 45).
( )
0
5
10
15
20
25
-4.9
9 to
-4.5
-4.4
9 to
-4.0
-3.9
9 to
-3.5
-3.4
9 to
-3.0
-2.9
9 to
-2.5
-2.4
9 to
-2.0
-1.9
9 to
-1.5
-1.4
9 to
-1.0
-0.9
9 to
-0.5
-0.4
9 to
0.0
0.01
to 0
.5
0.51
to 1
.0
1.01
to 1
.5
1.51
to 2
.0
2.01
to 2
.5
2.51
to 3
.0
3.01
to 3
.5
3.51
to 4
.0
4.01
to 4
.5
4.51
to 5
.0
IV
-
45. 711
-
82
, , . 92.4% (95% 89.5-94.6) , 2.5% (95% 1.5-4.0) 0.8% (95% 0.4-1.6) , 3.7% (95% 2.3-5.9) , 0.6% (95% 0.2-1.6) . 711 , ( 50).
50. 7 11 ,
95% 95% 95% 95%
226 3,5 1,8-7,0 1,8 0,7-4,4 1,8 0,7-4,4 0,4 0,1-3,2 240 0,8 0,2-3,4 0,4 0,1-2,9 0,8 0,2-3,2 0,8 0,1-5,8 239 2,5 0,8-7,3 0,4 0,1-3,0 2,1 0,9-4,6 0 - 254 3,1 1,6-6,3 1,6 0,5-5,0 1,6 0,6-3,9 0 - 244 2,9 1,2-6,6 0,8 0,2-3,2 7,0 3,9-12,1 0,8 0,2-3,1
, , ( 46).
90.6
94.5
2.8
2.1
4.8
2.4
1.1
50% 60% 70% 80% 90% 100%
46. 7 11 ,
, . (5.2%, 95% 3.1-8.5) (1.1%, 95% 0.5-2.3) 4.7 (p=0.004) ( 51).
51. 7 11 ,
95% 95% 95% 95%
624 2.7 1.5-5.1 0.9 0.4-2.1 5.2 3.1-8.5 0.8 0.3-2.4 579 2.0 1.1-3.6 0.8 0.3-1.9 1.1 0.5-2.3 0.2 0.0-1.1
. 711 88.4% (95% 85.8-90.5) , 9.3% (95% 7.4-11.5) , 2.4% (95% 1.6-3.6) .
( 47).
4.8 1.1
2.4
-
83
0
5
10
15
20
-5.9
9 to
-5.5
-5.4
9 to
-5.0
-4.9
9 to
-4.5
-4.4
9 to
-4.0
-3.9
9 to
-3.5
-3.4
9 to
-3.0
-2.9
9 to
-2.5
-2.4
9 to
-2.0
-1.9
9 to
-1.5
-1.4
9 to
-1.0
-0.9
9 to
-0.5
-0.4
9 to
0.0
0.01
to 0
.5
0.51
to 1
.0
1.01
to 1
.5
1.51
to 2
.0
2.01
to 2
.5
2.51
to 3
.0
3.01
to 3
.5
3.51
to 4
.0
4.01
to 4
.5
IV -
47. 711
711 , / Z 2 1 . , . 711 14.6% (95% 10.9-19.7) , 7.1% (95% 3.6-13.5) , ( 52).
52. 711 ,
95% 95%
226 14.6 10.7-19.7 7.1 3.6-13.5
240 7.9 5.2-12.0 1.3 0.4-3.7
239 10.9 6.7-17.1 0.8 0.1-5.8
254 12.6 8.7-18.0 3.1 1.6-6.1
244 7.0 3.9-12.0 2.0 3.9-12.0
1203 9.3 7.4-11.5 2.4 1.6-3.6
. , 9% (95% 6.7-12.1) , 2.1% (95% 1.1-3.7) , 9.5% (95% 6.6-13.5) , 2.7% (95% 1.6-4.7) ( 53).
53. 7 11 ,
95% 95%
558 9.0 6.7-12.1 2.1 1.1-3.7 484 9.5 6.6-13.5 2.7 1.6-4.7
, 15.2% (95% 11.7-19.5), 9.6% (95% 7.0-13.1) (p=0.02). 1.6 ( 48).
-
84
7.71.9
9.612.1
3.2
15.2
0
3
6
9
12
15
18
48. 7 11 ,
, ( 54).
54. 7 11 ,
95% 95%
7 252 6.9 4.0-11.5 0.7 0.2-2.58 271 8.9 5.5-14.1 0.7 0.2-2.59 282 10.8 6.8-16.5 3.2 1.5-6.510 311 9.3 6.3-13.5 3.9 2.1-7.211 87 12.4 5.5-25.5 4.0 1.5-10.4
, 11 12.4% (95% 5.5-25.5) 4.0% (95% 1.5-10.4) 7 6.9% (95%4.0-11.5) , 0.7% (95% 0.2-2.5) .
4.2.3 7-11
711 11.8% (95% 9.2-15.0) , 88.2% (95% 84.9-90.8) . ( 55).
55. 7 11 ,
95% 95%
15 6,6 3.6-12.0 211 93,4 88.0-96.4
50 20,7 15.6-27.0 191 79,3 73.0-84.4
20 8,4 5.5-12.5 219 91,6 87.5-94.5
14 5,5 2.7-10.6 241 94,5 89.2-96.9
28 11,4 6.5-19.3 217 88,6 80.7-93.5
, (: 6, 49).
-
85
0
10
20
30
8
7
7
8
7.713.4
9
1
10
4.320.8
11
49. 7 11 ,
( 56).
56. 7 11 ,
95% 95% 95%
641 9.9 7.3-13.3 90.1 86.7-92.7 0 -
566 13.9 10.4-18.4 86.0 81.5-89.6 0.1 0.0-0.5
(12.4%, 95% 7.7-19.3), (11.3%, 95% 9.0-14.0) . 711 60.0% (95% 47.6-71.2) , 3.2% (95% 1.1-9.6) , 5.9% (95% 2.6-12.8) 0.8% (95% 0.1-5.1) , 30.1% (95% 21.0-41.1) ( 50).
50. 7 11
. , 28.6% (95% 12.4-53.1) 82% (95% 65.2-91.7) (: 7, 51).
53.3
82
40 28.6
75
0
20
40
60
80
100
51. 7 11 ,
3.2%
5.9%0.8%
30.1% 660.0%
-
86
68.9% (95% 53.4-81.1) 71.8% (95% 57.5-82.7) . 711 , (65.9%, 95% 52.2-77.4), (73.2%, 95% 59.8-83.4) .
4.2.4 ,
711 48.6% (95% 43.9-53.4) , 46% (95% 40.5-51.7) 5.3% (95% 3.4-8.4) . ( 57).
57. 7 11 ,
95% 95% 95%
226 55.8 46.0-65.1 38.9 29.5-49.3 5.3 2.9-9.4
241 74.7 67.2-81.0 22.0 15.8-29.8 3.3 1.5-7.0
239 39.7 33.5-46.3 53.6 44.9-62.0 6.7 3.2-13.5
256 30.5 21.5-41.1 59.8 46.7-71.6 9.8 5.8-16.1
245 40.4 30.7-51.0 54.7 42.4-66.4 4.9 1.6-13.9
( 52).
32.6 33.348.7
64.583.7
0
20
40
60
80
100
7 8 9 10 11
52. 7 11 ,
, 78 32.6% (95% 24.1-42.4) 33.3% (95% 26.8-40.4) 1011 64.5% (95% 56.6-71.7) 83.7% (95% 71.2-91.4) .
, ( 58).
58. 7-11 ,
95% 95% 95%
641 45.3 39.1-51.6 48.4 41.3-55.6 6.3 4.0-9.7 566 52.5 47.5-57.5 43.2 37.7-49.0 4.3 2.2-8.1
-
87
, (46.5%, 95% 39.6-53.5), (52.5%, 95% 46.2-58.8) .
. 24.5% (95% 18.5-31.6) , 33.5% (95% 28.2-39.3) , 3.7% (95% 2.2-6.3) , 36.8% (95% 30.4-43.7) ( 53).
53. 7 11
, , ( 59).
59. 7 11 ,
95% 95% 95% 95% 95%
226 24.6 15.1-37.5 6.3 2.5-15.0 2.4 0.8-6.9 22.2 13.7-34.0 44.4 28.4-61.7 241 22.2 15.8-30.3 1.7 0.5-5.0 1.1 0.3-4.2 57.3 47.3-63.5 17.8 11.3-26.8 239 24.2 14.1-38.3 6.3 2.3-16.2 0 - 15.8 8.4-21.5 53.7 39.3-67.5 256 7.7 3.0-18.5 0 - 0 - 20.5 11.3-34.3 71.8 57.8-82.5 245 29.3 15.9-47.5 4.0 1.4-11.2 0 - 27.3 17.1-40.5 39.4 25.4-55.4
, 71.8% (95% 57.8-82.5) , 711 17.8% (95%11.3-26.8) . , 7.7% (95%3.0-18.5) .
711 3 1 34.3% (95% 28.9-40.2) , , 0.7% (95% 0.3-1.7) ( 54).
)
24.5%
3.7%0.7%
33.5%0.9%
36.8%
-
88
24.2 18.2 27.4 26.5491.1 0.5
0.839.1 42.7 32.5 35.619.8
36.8 39.1 38.3 37.4 30.3
0%
20%
40%
60%
80%
100%
7 8 9 10 11 54. 711 ,
11 (49%, 95% 32.3-66.0) (=0.04).
30.5% (95% 21.3-41.6), 24.4% (95% 18.4-31.7) . , . 711 14.3% (95% 11.2-18.0) , , 75.1% (95% 70.6-79.1) ( 60). 60. 711 ,
,
95% 95% 95%
126 11.9 7.0-19.5 69.0 51.5-82.4 19.0 7.3-41.4 180 20.6 13.7-29.6 65.0 59.2-70.3 14.4 9.6-21.2 95 12.6 8.3-18.8 85.3 78.4-90.2 2.1 0.3-14.0 78 19.2 10.6-32.3 62.8 45.6-77.3 17.9 10.2-29.6 99 9.1 5.2-15.5 84.8 76.0-90.8 6.1 2.9-12.4
, 20.6% (95% 13.7-29.6) .
7 , (2.3%, 95% 0.5-9.1) (p=0.05) (: 8, 55).
2.318.4 16.8 17.7 9.9
86.174.6 71.2 70.5 81.7
11.7 7 12 11.8 8.4
0%
20%
40%
60%
80%
100%
7 8 9 10 11
55. 711 ,
-
89
, 12.9% (95% 9.0-18.2), 16.4% (95% 11.9-22.2) .
4.2.5
1207 , .
711 7.3% (95% 5.8-9.2) . I 7.1% (95% 7.7-20.7), II 0.3% (95% 7.7-20.7) ( 61).
61. 711 ,
I II
95% 95% 95%
226 9.3 6.2-13.7 0 - 9.3 6.2-13.7
241 12.0 7.9-17.9 0 - 12.0 7.9-17.9
239 5.4 3.5-8.5 0.4 0.1-3.0 5.9 3.6-9.3
256 7.0 5.3-9.3 0.4 0.1-2.8 7.4 5.7-9.6
245 4.5 2.4-8.4 0.4 0.1-2.8 4.9 2.8-8.6
(12.0%, 95% 7.9-17.9) , (4.5%, 95% 2.4-8.4) .
( 56).
79.1
4.68.7 7
02468
10
7 8 9 10 11
56. ,
711 , ( 62).
62. 711 , ,
I II
95% 95% 95%
641 6.5 4.4-9.4 0 - 6.5 4.4-9.4
566 7.7 5.7-10.5 0.6 0.2-2.1 8.3 6.2-11.0
625 6.9 4.9-9.8 0.3 0.1-1.6 7.3 5.2-10.0
582 7.3 5.4-9.8 0.2 0.0-1.5 7.5 5.5-10.1
-
90
II 0.6% (95% 0.2-2.1) .
4.2.6
1120 , , , .
711 171.2/ - (100.0-199.9/) . 57- .
0
10
20
30
40
50
,
57. , /
57- 711 100/ . . , 187.1/ (95% 172.5-203.3), 155.0 / (95% 144.4-168.6) .
100 / ( 63).
63. 711 ,
, /
(
-
91
100 / . , 18.2% (95% 14.2-23.0), 30.6% (95% 24.9-37.0) .
711 1207 , , . 711 11.7% . 711 , .
() III 2007 711 , . 711 27.4 , 129.0 . 27.7, 129.2 . 2007 .
19921995, 1999, 2004, 2007 . 19962010 3 . .
711 , , . , 711 11.8 , 48.6 . 2007 ( 58).
26.7
78.2
11.8
48.6
0
20
40
60
802007
2010
58. , 7 11 ,
711 7.3 . 2004 III 6.5 , 19921995 4 ( 59).
-
92
29.2
21.4
13.8 12.8
7.4
0
5
10
15
20
25
30
35
1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011
7.3
59. 7-11 ,
. . 100 / . 171.2 / III , 2007 ( 60).
96.8
151.8171.2
0
50
100
150
200
2003 2004 2005 2006 2007 2008 2009 2010 2011
,/
60. 7-11 (/),
. .
2004 2007 . , , ( 64).
-
93
64. ,
, , %
(0-99,9 /)
(100-299,9 /)
(300/)
, , III , 2004
59652.9 41.0 6.2
, 2007
83230.4 60.3 9.3
IV , 2010
112022.9 55.0 22.1
100 / . , .
. . . 8 . , . . , - . 9.
1. 711 92.4 , 3.3 , 4.3 .
2. 711 10 1 , , 1.6 .
3. 711 11.8 , 48.6 , 2007 14.9 29.6 .
4. 711 7.3 1995 4 .
5. 711 171.2 / .
8 Braverman L. E et al., Iodine and the thyroid 33 years of study, Thyroid, 1994, 4:351-356.9 Dai G., Levy O., Carraco N., Cloning and characterization of the thyroid iodide transporter. Nature, 1996, 379: 458-460
-
94
4.3.
4.3.1. ,
17-46 975 . 189, 194, 198, 200 .
61. ,
20-29 ( 61).
1.6
5.2
8.2
4.5
3.5
65.6
65.5
64.9
64.2
68
29.1
26.7
26.4
28.8
26
3.7
2.6
0.5
2.5
2.5
0 10 20 30 40 50 60 70 80 90 100
15-19 20-29 30-39 40-49
62. , ,
40-49 , 15-19 , 15-19 , 40-49 . 20-29, 30-39 ( 62).
65. ,
13 1.0 150 13.9
27 2.2 - 24 3.2
60 5.0 88 10.1
160 13.5 95 11.5
385 40.4 / 117 13.4
/ 29 2.4 35 4.8
301 35.5 192 15.6
272 27.4
2 0.2
15-19 ,4.5%
20-29 ,66.3%
30-39 ,26.8% 40-49 ,
2.3%
-
95
78.3% , 8.2% , , ( 65).
66.
59 5.7
724 72.6
29 2.9
2 0.1
2 0.2
159 18.5
, . 5.7% ( 66).
2.37 (95% 2.26-2.49) ( 67).
67. ,
,
( )
324 33.1 0-12 112 12.5
2-4 572 58.8 13-22 301 32.0
5 78 8.1 23 562 55.5
, ( 68).
68.
975
971
973
927
532
4.3.2.
, , , , , , . .
973 ( 63).
-
96
0
2
4
6
8
10
12
14
16
11 12 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40
()
( )
63.
27.1 (95% 26.8-27.3) . 24-28 56.3%, 34-40 2.4% .
22 - ( ) 2.1% (95% 1.3-3.5) (p
-
97
69. ,
95%
259 10 3.4 1.7-6.7 714 14 1.8 1.0-3.3
1.9 , .
4.3.3.
971 . 15 (1.9%) 1 20 .
0
5
10
15
20
25
30
35
6 7 8 9 10 11 12 13 14 15
()
( / )
65. 10, /
( 65).
26.5% (95% 23.2-30.1) .
66. ,
0.1% (95% 0.1-0.8) , 8.5% (95% 6.7-10.8) , 17.9% (95% 15.2-20.9) ( 66).
- ,0.1%
- ,8.5%
- ,17.9%
- ,73.5%
10
-
98
37.6% ( 70).
70. , ,
,
95%
189 54 28.6 22.8-35.1 - 12.2 16.4 194 73 37.6 29.3-46.7 0.5 14.4 22.7 194 32 16.5 11.6-23.0 - 3.6 12.9 198 39 19.8 13.1-28.7 - 8.1 11.7 200 51 25.9 20.1-32.7 - 6.6 19.3
498 114 24.0 19.9-28.7 - 6.4 17.6 473 135 31.0 26.0-36.5 0.3 12.3 18.4
. (X 90).
. (0.3%, 95% 0.0-2.1) . (12.3%, 95% 4.4-9.3)- (6.4%, 95% 9.3-16.2) . (X 70).
, ( 71)
71. ,
-
,
95% 15-19 45 10 26,4 14.5-43.1 0 9.2 17.1
20-29 638 166 26.6 22.6-30.9 0 8.2 18.4
30-39 266 64 25.5 20.1-31.8 0.4 8.5 16.6
40-49 22 9 39.5 19.7-63.5 0 18.5 21.0
40-49 . 30-39 .
, ( 72)
-
99
72. , ,
-
,
95%
323 74 25.4 20.0-31.7 - 7.1 18.42-4 570 156 27.9 23.9-32.2 0.2 8.8 18.95 77 19 21.9 12.3-35.9 - 13.3 8.6
( )0-12 111 7 4.6 1.8-11.3 - 0.9 3.713-22 299 69 24.3 18.2-31.5 - 4.8 19.523 560 172 32.6 28.2-37.3 0.2 12.2 20.2
. 12 (p
-
100
4.3.4. , : 63 (6.9%, 95% 5.0-9.5) 1-10 . 28.8% (95% 25.1-32.8) 11-59, 11.4% (95% 8.9-14.4) 60-89, 6.4% (95% 4.9-8.3) 90-200 , 46.6% (95% 42.5-50.8) 11-200 .
( 67).
47.1 44.3 47.9
60.1
44.5
0
10
20
30
40
50
60
70
67. ,
45.8% (95% 40.1-51.6), 48.2% (95% 42.6-53.7) . ( 74).
74. ,
,
, 11-59 60-89 90-200
95% 95% 95% 95%
, 0-12 112 6.8 2.5-17.3 0.7 0.1-5.2 0 - 7.5 0.3-17.7
13-22 301 25.0 20.0-30.9 5.9 3.4-9.9 2.0 0.9-4.6 32.9 26.9-39.5
23 561 36.0 30.4-42.0 17.0 13.1-21.8 10.5 8.1-13.4 63.5 57.7-68.9 ,
< 260 27.6 21.8-34.2 12.0 8.1-17.3 5.3 3.0-9.2 44.8 37.2-52.6
715 29.2 24.8-33.9 11.2 8.2-15.1 6.8 5.1-9.0 47.2 42.3-52.0
(p
-
101
- : 14 (1.0%, 95% 0.6-1.8) 1-10 . 8.2% (95% 6.2-10.7) 11-59, 2.6% (95% 1.7-4.0) 60-89, 1.1% (95% 0.5-2.4) 90-190 , 11.9% (95% 10.1-16.4) 11-190 .
- (p
-
102
15.5% (95% 8.9-25.4), 7.1% (95% 2.3-19.6), 1.0% (95% 0.2-4.0) .
42.1% (95% 37.6-46.7) , , 21.0% (95% 17.2-25.3) , . 38.6% (95% 34.4-42.8) , 24.1% (95% 19.9-28.9) . , . 2.4% , . , 25.0% (95% 20.2-30.6), 27.7% (95% 23.7-32.0) .4.3.5.
(median) 150-499 / 11. 69- .
0%
1%
2%
3%
4%
5%
0 20 40 60 80 100 120 140 160 180 200 220 240 260 280 300 320 340 360 380 400 420 440 460 480 500 520 550 580 600+
,
69. , /
151.5 / (150/) . ( 70).
128.9 135.5186.7
139.7182.9
0.0
50.0
100.0
150.0
200.0
250.0
,
/
70. (/),
70- , , . . ( 155.3/, 149.3/) .
11 WHO, UNICEF, ICCIDD, Assessment of iodine deficiency disorders and monitoring their elimination, Third edition, Page 33.
-
103
46.8% (95% 42.5-51.2) 150 /- , . (: 10).
4.3.6.
. 532 , , . , .
72.3% (95% 68.7-75.7) . , ( 76).
76. ,
95% 95% 95%
189 97.9 94.7-99.2 2.1 0.8-5.3 0 - 194 83.5 78.4-87.6 16.5 12.4-21.6 0 - 194 62.9 50.1-74.1 37.1 25.9-49.9 0 - 198 17.2 11.2-25.5 82.8 74.5-88.8 0 - 200 73.5 67.0-79.1 26.0 20.2-32.8 0.5 0.1-3.5
. , 74.3% (95% 68.4-79.5), 70.6% (95% 66.1-74.7) . 70 ( 71).
72.7 73.2 70.1 70.9
0
20
40
60
80
100
15-19 20-29 30-39 40-49
71. ,
500 . . 8.5 (95% 7.9-8.9) . (12.0, 95% 10.3-13.6) (: 11, 72).
-
104
( )
12.09.1 7.3 8.9 7.5
0.0
3.0
6.0
9.0
12.0
15.0
,
72. (),
, , 16.0 (95% 14.0-17.9) . (: 11, 73).
14.8 16 16.110.8
17.3
0
4
8
12
16
20
24
,
73. (),
86- 10.8 (95% 9.0-12.5) . , .
, ( 77).
77. (), ,
() 95%
275 15.7 12.9-18.4
257 16.4 13.9-18.8
15 29 384 16.5 14.5-18.5
30 49 148 14.6 10.4-18.7
15.7 (95% 12.9-18.4), 16.4 (95% 13.9-18.8) .
-
105
4.3.7.
: , , , . 59.5% (95% 54.7-64.1) , 39.5% (95% 34.9-44.4) , 1% (95% 0.4-2.5) ( 78).
78. ,
95% 95% 95%
189 47.1 38.3-56.0 51.9 43.2-60.4 1.1 0.1-7.3 194 58.2 46.0-69.5 40.7 29.8-52.7 1.0 0.3-4.0 194 53.1 45.6-60.5 45.9 38.6-53.3 1.0 0.3-4.0 198 53.5 45.6-61.3 46.0 38.1-54.1 0.5 0.1-3.6 200 68.0 58.9-75.9 31.0 22.8-40.5 1.0 0.1-6.9
, .
(: 12, 74).
44.957.6 66.3 63.6
0
20
40
60
80
100
15-19 20-29 30-39 40-49
74. ,
, 1519 44.9% (95% 28.3-62.8), 20 29 57.6% (95% 52.1-63.0), 3049 60 .
16.7 (=0.005) ( 79).
79. ,
95% 95% 95%
501 65.5 59.2-71.4 33.8 27.8-40.4 0.6 0.1-4.5 474 48.8 42.1-55.6 49.6 43.0-56.2 1.6 0.7-3.5
11.6% (95% 8.1-16.3) , 76.7% (95% 71.8-81.0) , 2.2% (95% 1.1-4.3) 9.1% (95% 6.6-12.4) ( 75).
-
106
75.
( 80).
80. ,
95% 95% 95% 95%
189 22.5 13.1-35.8 58.4 45.0-70.7 2.2 0.2-7.4 16.9 8.7-30.2
194 7.1 3.3-14.5 86.7 80.0-91.4 2.7 0.9-7.4 3.5 1.4-8.9
194 9.7 5.4-16.8 77.7 68.4-84.8 1.0 0.1-6.6 11.7 6.1-21.0
198 12.3 5.9-23.7 63.2 51.5-73.6 0 - 24.5 16.0-35.6
200 11.8 6.0-21.9 77.9 68.4-85.2 3.6 1.1-7.6 6.6 3.3-13.0
(86.7%, 95% 80.0-91.4) . 24.5% (95% 16.0-35.6) .
4049 90% (95% 70.2-97.2) . (: 13, 76).
47.3
79.6 72.990
0
20
40
60
80
100
15-19 20-29 30-39 40-49
76. ,
, , 77.8% (95% 71.3-83.1), 74.2% (95% 66.4-80.7) ( 81).
( )
11.6%
76.7%
2.2%0.5%
9.1%
-
107
81. ,
95% 95% 95% 95%
315 11.2 6.9-17.7 77.8 71.3-83.1 2.4 1.0-5.3 8.1 5.3-12.4
232 12.3 7.7-19.2 74.2 66.4-80.7 1.8 0.6-5.0 11.3 7.1-17.5
: 92% (95% 89.6-93.9) , 7.1% (95% 5.3-9.5) , 0.9% (95% 0.4-1.8) . , ( 82).
82. ,
95% 95% 95%
189 89.4 82.8-93.7 8.5 4.5-15.5 2.1 0.7-6.6
194 87.6 80.2-92.6 11.9 7.1-19.2 0.5 0.1-3.7
194 93.3 87.8-96.4 5.7 2.8-11.1 1.0 0.3-4.0
198 89.4 81.9-94.0 9.1 5.1-15.6 1.5 0.5-4.5
200 95.0 90.6-97.4 4.5 2.2-9.0 0.5 0.1-3.5
75.1% (95% 70.9-78.8) , 4.7% (95% 3.2-6.9) , 10.8% (95% 8.2-14.3) , 8.4% (95% 0.1-0.9) ( 77).
77.
(82.6%, 95% 74.5-88.5) (60.4%, 95% 49.9-70.0) (66.1%, 95% 59.0-72.6) ( 83).
83. ,
95% 95% 95% 95% 95%
169 60.4 49.9-70.0 3.0 1.3-6.5 1.8 0.4-7.4 17.2 10.6-26.6 17.8 12.3-24.9
170 71.2 62.3-78.7 6.5 3.4-11.9 1.2 0.3-4.6 15.9 10.6-21.6 5.3 2.6-10.5
181 75.7 65.8-83.5 7.2 4.3-11.7 0.6 0.1-3.9 6.7 2.9-12.4 9.9 6.0-16.1
177 66.1 59.0-72.6 2.3 0.7-7.1 0.6 0.1-4.0 13.6 9.3-19.3 17.5 11.9-25.1
190 82.6 74.5-88.5 3.7 1.4-9.3 0.5 0.1-3.7 8.4 4.1-16.6 4.7 2.7-8.1
75.1%
4.7%0.8%
10.8%
0.2% 8.4%
-
108
( 78).
66.3 74.3 78.4 75.7
0
20
40
60
80
100
15-19 20-29 30-39 40-49
78. ,
78- 20 4 3 . (12.1%, 95% 9.0-16.1) (6.4%, 95% 4.6-8.8) 1.9 ( 84).
84. ,
95% 95% 95% 95% 95%
468 80.1 74.7-84.6 4.2 2.3-7.5 0.3 0.0-2.4 8.8 5.5-13.8 6.4 4.6-8.8
419 65.6 59.0-71.7 5.6 3.6-8.5 1.7 0.7-3.9 14.7 11.0-19.4 12.1 9.0-16.1
(80.1%, 95% 74.7-84.6) (65.6%, 95% 59.0-71.7) 103- (p=0.005).
88.1% (95% 85.0-90.6) ( 79).
79.
(63.5%, 95% 51.7-73.8) ( 85).
88.1
0.9
9.9
1.1
-
109
85. ,
95% 95% 95% 95%
189 63.5 51.7-73.8 4.8 2.3-9.5 30.2 21.4-40.7 1.6 0.5-4.7 194 91.8 86.2-95.2 0 - 7.2 3.9-13.0 1.0 0.3-4.0 194 84.5 75.7-90.6 1.5 0.5-4.5 13.4 8.4-20.6 0.5 0.1-3.6 198 94.9 90.5-97.4 0.5 0.1-3.6 2.0 0.8-5.1 2.5 0.9-6.7 200 94.0 87.7-97.2 5.0 2.2-10.8 0 - 1.0 0.3-3.9
(30.2%, 95% 21.4-40.7) . . (p=0.003) ( 86).
86. ,
95% 95% 95% 95%
501 91.5 87.3-94.4 0.5 0.2-1.2 7.2 4.6-10.9 0.9 0.3-2.6
474 82.1 76.6-86.5 1.7 0.8-3.5 14.7 10.9-19.6 1.5 0.7-3.0
, 9.4 105- . .
82.3% (95% 73.4-88.7) , 10.8% (95% 5.8-19.3) , 5.4% (95% 2.2-12.9) ( 80).
80.
87.4% (95% 83.5-90.5) , 11.6% (95% 8.6-15.5) , 0.6% (95% 0.2-1.4) ( 87).
( ) (
5.4%0.6%
10.8%
0.9%
82.3%
-
110
87. ,
95% 95% 95% 95% 95%
189 77.0 66.5-85.0 18.2 11.0-28.5 3.7 1.3-10.4 0.5 0.1-3.8 0.5 0.1-3.8
194 91.2 82.5-95.8 8.8 4.2-17.4 0 - 0 - 0 -
194 87.6 72.6-95.0 11.9 4.6-27.3 0.5 0.1-3.6 0 - 0 -
198 91.4 83.3-95.8 8.1 4.2-15.1 0 - 0.5 0.1-3.6 0 -
200 87.8 81.0-92.4 11.7 7.2-18.4 0 - 0 - 0.5 0.1-3.6
1 . 503 (95% 477.0-528.9) ( 81).
700.5539
402.8522.1 463.8
0
200
400
600
800
,
81. (),
81- . .
4.3.8.
, , . 58.5% (95% 54.4-62.4) . 40.2% (95% 35.5-45.1) ( 88).
88. ,
95% 95%
189 119 63.0 54.6-70.6 90 47.6 38.6-56.8 194 112 57.7 50.4-64.8 77 39.7 31.5-48.5
194 120 61.9 51.7-71.1 84 43.3 35.3-51.7 198 105 53.0 47.0-59.0 58 29.3 23.0-36.5 200 114 57.0 49.2-64.5 78 39.0 29.6-49.3
. , ( 82).
-
111
24.539.1 46.6
28.5
0102030405060
15-19 20-29 30-39 40-49
82. ,
34.9% (95% 31.0-39.0) , . 28.3% (95% 22.5-34.9), 40.2% (95% 32.3-48.6) . , 34.6% (95% 29.5-39.9), 35.5% (95% 29.6-41.8) .
(n=387) . , , , , , , , ( 89).
89.
95%
3 0.7 0.2-3.1
108 28.2 22.3-35.0
76 20.5 14.6-27.9
, 111 30.7 24.7-37.5
99 26.8 20.5-34.2
84 23.7 17.4-31.3
55 15.9 11.0-22.3
( , ) 3 1.2 0.4-3.9
83- .
16.7 31.2 35.7 31 26.90
20
40
60
83. ,
-
112
(50%, 95% 34.2-65.8) (: 14, 84).
11.1 11.7 50 3.4 16.70
10203040506070
84. ,
, 48.8% (95% 34.1-63.8), 33.3% (95% 22.4-46.3) . , (: 14, 85).
18.9 20.8 48.8 19 33.30
10203040506070
85. ,
,
60.7% (95% 45.3-74.2) (: 14, 86).
10 15.6 60.7 13.8 24.40
20
40
60
80
86. ,
, , 8.6% - 26.9% . 32% (95% 27.6-36.8)
-
113
, 6.3% (95% 4.6-8.7) ( 90).
90. ,
95% 95%
189 32 16.9 10.8-25.5 9 4.8 2.5-8.9 194 65 33.5 25.4-42.7 10 5.2 2.7-9.7 194 72 37.1 30.0-44.8 8 4.1 2.3-7.3 198 55 27.8 21.3-35.3 12 6.1 3.7-9.8 200 69 34.5 25.6-44.6 17 8.5 5.1-14.0
, . , . , .
. 7.1% (95% 5.2-9.6) ( 87).
5.3 13.4 7.7 7.1 40
5
10
15
20
87. ,