© 2004 nu skin ® system presentation nu skin ® tri-phasic white ™ the scientific method for...
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© 2004 Nu Skin®
SYSTEM PRESENTATION
Nu Skin® Tri-Phasic White™
The Scientific Method for Brilliant Skin
© 2004 Nu Skin®
SYSTEM PRESENTATION
Nu Skin® Tri-Phasic White™
The Scientific Method for Brilliant Skin
System Presentation ›
NU SKIN® TRI-PHASIC WHITE™ The scientific method for brilliant skin
© 2004 Nu Skin®
SYSTEM PRESENTATION
Nu Skin® Tri-Phasic White™
The Scientific Method for Brilliant Skin
The Beauty of Fair Skin
© 2004 Nu Skin®
SYSTEM PRESENTATION
Nu Skin® Tri-Phasic White™
The Scientific Method for Brilliant Skin
The Beauty of Fair, Even Skin
© 2004 Nu Skin®
SYSTEM PRESENTATION
Nu Skin® Tri-Phasic White™
The Scientific Method for Brilliant Skin
Leading Skin Care Researchers
© 2004 Nu Skin®
SYSTEM PRESENTATION
Nu Skin® Tri-Phasic White™
The Scientific Method for Brilliant Skin
Dr. Bryan Fuller
© 2004 Nu Skin®
SYSTEM PRESENTATION
Nu Skin® Tri-Phasic White™
The Scientific Method for Brilliant Skin
The Pigmentation Process
© 2004 Nu Skin®
SYSTEM PRESENTATION
Nu Skin® Tri-Phasic White™
The Scientific Method for Brilliant Skin
Where Does the Pigmentation Process Begin?
• Lower part of epidermis
© 2004 Nu Skin®
SYSTEM PRESENTATION
Nu Skin® Tri-Phasic White™
The Scientific Method for Brilliant Skin
Role of the Melanocyte
• Melanocytes are located just below a layer of surface skin cells called keratinocytes.
Melanin in production
Melanocytes
Layers of keratinocytes
Epidermis
Melanin visible at the surface of the skin.
© 2004 Nu Skin®
SYSTEM PRESENTATION
Nu Skin® Tri-Phasic White™
The Scientific Method for Brilliant Skin
Pigmentation Process: Three Phases
• Activation: melanin production is initiated.• Synthesis: melanin is actually produced
by melanocytes. • Expression: melanin is transported to
surface of the skin.
© 2004 Nu Skin®
SYSTEM PRESENTATION
Nu Skin® Tri-Phasic White™
The Scientific Method for Brilliant Skin
Activation Phase
© 2004 Nu Skin®
SYSTEM PRESENTATION
Nu Skin® Tri-Phasic White™
The Scientific Method for Brilliant Skin
Factors Causing Melanin Production
HormonesStress
UV Light
© 2004 Nu Skin®
SYSTEM PRESENTATION
Nu Skin® Tri-Phasic White™
The Scientific Method for Brilliant Skin
Synthesis Phase
© 2004 Nu Skin®
SYSTEM PRESENTATION
Nu Skin® Tri-Phasic White™
The Scientific Method for Brilliant Skin
Synthesis Phase
Following the activation phase, the melanocyte begins the synthesis of melanin. Three main chemical reactions exist within the synthesis phase.
Layers of keratinocytes
(skin cells)
Melanin is formed inside the melanocyte.
Epidermis
Melanocyte
© 2004 Nu Skin®
SYSTEM PRESENTATION
Nu Skin® Tri-Phasic White™
The Scientific Method for Brilliant Skin
Tyrosine to Dopa
Tyrosine Dopa
Tyrosinase
1. Tyrosinase, an enzyme essential to melanin synthesis, functions to convert tyrosine, an amino acid, to another amino acid called dopa.
© 2004 Nu Skin®
SYSTEM PRESENTATION
Nu Skin® Tri-Phasic White™
The Scientific Method for Brilliant Skin
Dopa to Dopaquinone
Tyrosine Dopa Dopaquinone
Tyrosinase
2. Tyrosinase then converts dopa into dopaquinone, a secondary chemical.
© 2004 Nu Skin®
SYSTEM PRESENTATION
Nu Skin® Tri-Phasic White™
The Scientific Method for Brilliant Skin
Dopaquinone to Phaeo or Eu Melanin
Tyrosine Dopa
Phaeo-melanin
Dopaquinone
Eu-melanin
3. Dopaquinone, in a final reaction, is converted into one of two types of melanin.
TyrosinaseTyrosinase
© 2004 Nu Skin®
SYSTEM PRESENTATION
Nu Skin® Tri-Phasic White™
The Scientific Method for Brilliant Skin
Phaeo and Eu Melanin
Phaeo-melanin
Dopaquinone
Eu-melanin
© 2004 Nu Skin®
SYSTEM PRESENTATION
Nu Skin® Tri-Phasic White™
The Scientific Method for Brilliant Skin
Synthesis of Melanin
Efficiently “packaged” within a melanosome, the melanin is now ready for delivery to the skin in the expression phase.
Melanin in production
Melanocytes
Layers of keratinocytes
Epidermis
Melanin visible at the surface of the skin.
© 2004 Nu Skin®
SYSTEM PRESENTATION
Nu Skin® Tri-Phasic White™
The Scientific Method for Brilliant Skin
Expression Phase
© 2004 Nu Skin®
SYSTEM PRESENTATION
Nu Skin® Tri-Phasic White™
The Scientific Method for Brilliant Skin
Expression Phase: The ProcessMelanin becomes visible at the
surface of the skin.
Melanin-filled melanosomes move up dendrite-like arms of the melanocyte and are deposited inside the keratinocytes.
Layers of keratinocytes (skin cells)
Melanocyte
Detailed illustration of melanocyte
© 2004 Nu Skin®
SYSTEM PRESENTATION
Nu Skin® Tri-Phasic White™
The Scientific Method for Brilliant Skin
Expression of Melanin on Skin’s Surface
Melanin in production
Melanocytes
Layers of keratinocytes
Epidermis
Melanin visible at the surface of the skin.
© 2004 Nu Skin®
SYSTEM PRESENTATION
Nu Skin® Tri-Phasic White™
The Scientific Method for Brilliant Skin
© 2004 Nu Skin®
SYSTEM PRESENTATION
Nu Skin® Tri-Phasic White™
The Scientific Method for Brilliant Skin
The Discoloration ProcessIn addition to the normal pigmentation process, where the hormone MSH initiates the activation of melanin synthesis, other factors can also cause melanin production.
Hormones(Pregnancy)
Stress
Irritants(Pollution)
UV Light(Sun)
© 2004 Nu Skin®
SYSTEM PRESENTATION
Nu Skin® Tri-Phasic White™
The Scientific Method for Brilliant Skin
Melanocytes and Hyperpigmentation
Layers of keratinocytes
(skin cells)
Melanocyte
© 2004 Nu Skin®
SYSTEM PRESENTATION
Nu Skin® Tri-Phasic White™
The Scientific Method for Brilliant Skin
Activation Synthesis Expression
© 2004 Nu Skin®
SYSTEM PRESENTATION
Nu Skin® Tri-Phasic White™
The Scientific Method for Brilliant Skin
Nu Skin® Tri-Phasic White™ System
Targets all three phases of the skin discoloration pathway:
Activation Synthesis Expression DISCOLORATION
Activation Synthesis Expression
© 2004 Nu Skin®
SYSTEM PRESENTATION
Nu Skin® Tri-Phasic White™
The Scientific Method for Brilliant Skin
Tri-Phasic White™ System
A comprehensive skin brightening system, Tri-Phasic White™ works to minimize the activation, synthesis, and expression of discoloration on the skin’s surface.
© 2004 Nu Skin®
SYSTEM PRESENTATION
Nu Skin® Tri-Phasic White™
The Scientific Method for Brilliant Skin
System Benefits
Reduces the appearance of:• Existing dark spots• Uneven skin tone• Discoloration
Helps prevent the formation of:• New dark spots • Discoloration
Helps maintain:• Even skin tones• Bright skin tones
System Benefits
© 2004 Nu Skin®
SYSTEM PRESENTATION
Nu Skin® Tri-Phasic White™
The Scientific Method for Brilliant Skin
Clinical Study • 12-week clinical study.• 29 Japanese women, with mild to moderate
discoloration on the face.• Nu Skin® Tri-Phasic White™ System applied to
face twice per day according to standard use instructions.
• Consistent and cumulative improvements over weeks four, eight, and 12.
• Measured: brightness, radiance, even color, roughness improvement, area, and overall improvement.
© 2004 Nu Skin®
SYSTEM PRESENTATION
Nu Skin® Tri-Phasic White™
The Scientific Method for Brilliant Skin
• 93% improved in brightness.• 97% improved in radiance.• 97% improved in even skin color.• 79% improved in smoothness.• 83% decreased in area of mottled appearance.• 100% improved in overall appearance.
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Nu Skin® Tri-Phasic White™ Performance by Clinical Grader
% o
f Sub
ject
s wi
th Im
prov
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t
A B C D E F
A. BrightnessB. RadianceC. Even color
D. SmoothnessE. Mottled areaF. Overall improvement
© 2004 Nu Skin®
SYSTEM PRESENTATION
Nu Skin® Tri-Phasic White™
The Scientific Method for Brilliant Skin
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Nu Skin® Tri-Phasic White™ Self-Assessment
% Im
prov
emen
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A B C D E F
Questions Asked Participants
% of Positive Responses at 12 weeks
A Leaves skin moisturized? 97%
B Leaves skin soft? 76%C Products worked
well together? 86%
D Whitening ability? 58%E Leaves skin
brighter? 76%
F Lightens spots? 52%
© 2004 Nu Skin®
SYSTEM PRESENTATION
Nu Skin® Tri-Phasic White™
The Scientific Method for Brilliant Skin
Tri-Phasic White™ System Products
• Cleanser
• Toner
• Radiance Mask*
• Essence
• Day Milk Lotion
• Night Cream
* Sold separately. Radiance Mask is a line extension product of the Tri-Phasic White™ System.
© 2004 Nu Skin®
SYSTEM PRESENTATION
Nu Skin® Tri-Phasic White™
The Scientific Method for Brilliant Skin
Nu Skin® Tri-Phasic White™ Cleanser
Key Benefit• Reduces expression of discoloration by
inhibiting pigment transfer.
Key Ingredient• Creatinine—helps inhibit the transfer of
pigment.
© 2004 Nu Skin®
SYSTEM PRESENTATION
Nu Skin® Tri-Phasic White™
The Scientific Method for Brilliant Skin
Nu Skin® Tri-Phasic White™ Toner
Key Benefits• Reduces expression of discoloration. • Minimizes activation of discoloration.
Key Ingredients• Fairtrex™—non-acid exfoliation complex.• Carnosine— blocks irritation receptors.
© 2004 Nu Skin®
SYSTEM PRESENTATION
Nu Skin® Tri-Phasic White™
The Scientific Method for Brilliant Skin
Nu Skin® Tri-Phasic White™ Radiance Mask*Key Benefits
• Helps inhibit activation and synthesis of discoloration.
• Illuminates skin tone, promoting a radiant complexion.
Key Ingredients• Portulaca oleracea extract—targets the
activation of discoloration. • Tetrahydro-diferuloylmethane—helps block
the synthesis of discoloration.
* Sold separately. Radiance Mask is a line extension product of the Tri-Phasic White™ System.
© 2004 Nu Skin®
SYSTEM PRESENTATION
Nu Skin® Tri-Phasic White™
The Scientific Method for Brilliant Skin
Nu Skin® Tri-Phasic White™ Essence
Key Benefit• Inhibits synthesis of discoloration.
Key Ingredient• Brightex™—proprietary whitening blend that
helps inhibit the formation of melanin.
© 2004 Nu Skin®
SYSTEM PRESENTATION
Nu Skin® Tri-Phasic White™
The Scientific Method for Brilliant Skin
Nu Skin® Tri-Phasic White™ Day Milk Lotion
Key Benefit• Minimizes activation of discoloration.
Key Ingredients• Hexapeptide-2—partially blocks hormone
receptor.• UVA/UVB sunscreen (SPF 15)—helps
absorb and reflect high energy sun rays.
© 2004 Nu Skin®
SYSTEM PRESENTATION
Nu Skin® Tri-Phasic White™
The Scientific Method for Brilliant Skin
Nu Skin® Tri-Phasic White™ Night Cream
Key Benefit:• Minimizes activation of discoloration.
Key Ingredient:• Diacetyl boldine—blocks stress receptors.
© 2004 Nu Skin®
SYSTEM PRESENTATION
Nu Skin® Tri-Phasic White™
The Scientific Method for Brilliant Skin
ACTIVATION
of Discoloration
SYNTHESIS
of Discoloration
EXPRESSION
of Discoloration
Tri-Phasic White™ Cleanser
Creatinine
Tri-Phasic White™ Toner
Carnosine Fairtrex™
Tri-Phasic White™ Radiance Mask
Portulaca oleracea extract Tetrahydro-diferuloylmethane
Tri-Phasic White™ Essence
Brightex™
Tri-Phasic White™ Day Milk Lotion
Hexapeptide-2
UVA and UVB sunscreens SPF 15
Tri-Phasic White™ Night Cream
Diacetyl boldine
© 2004 Nu Skin®
SYSTEM PRESENTATION
Nu Skin® Tri-Phasic White™
The Scientific Method for Brilliant Skin
Usage
Day Night
Tri-Phasic White™ Cleanser Tri-Phasic White™ Cleanser
Tri-Phasic White™ Toner Tri-Phasic White™ Toner
Tri-Phasic White™ Radiance Mask* Tri-Phasic White™ Radiance Mask*
Tri-Phasic White™ Essence Tri-Phasic White™ Essence
Tri-Phasic White™ Day Milk Lotion Tri-Phasic White™ Night Cream
* Sold separately.
© 2004 Nu Skin®
SYSTEM PRESENTATION
Nu Skin® Tri-Phasic White™
The Scientific Method for Brilliant Skin
Live Better, Longer